Digital Commons Network^™

The Structure And Function Of A Coastal State Aquaculture Plan, C. R. Fong, C. M. Gonzales, M. Rennick, H. J. Lahr, L. D. Gardner, B. S. Halpern, H. E. Froehlich

Faculty Research, Scholarly, and Creative Activity

Aquaculture contributes approximately half of all global aquatic food production and will be critical in addressing future seafood demand, including the United States (U.S.). Many states, territories, and countries are developing and updating aquaculture specific policy in an effort to plan for, and better manage the expansion of aquaculture in their territorial waters. The U.S. has considerable potential to sustainably expand aquaculture production, which has been a focus in both federal and state policy. State aquaculture plans have been used for over 40 years to help plan and coordinate aquaculture development, with a growing emphasis on sustainability. Here, we located …

A Personal Journey Of Self-Reflection, Brooke Heil

Dissertations, Theses, and Projects

Abstract

In this analysis, I investigate the different layers that make up who I am, exploring my personal experiences, relationships, academic pursuits, career path, mental and physical health, cultural background, coping mechanisms, strengths, and aspirations. Coming from a family deeply impacted by alcoholism, mental health struggles, and loss, I navigate through life's challenges, drawing insights from various psychological theories to understand my own journey. Through self-reflection and insights from those around me, I explore themes of resilience, independence, and how my past shapes my present. This analysis was constructed with personal stories, reflections, and observations, providing a holistic view of …

Liv Selection In ‘Tweener’ Patients Treated With Magnetically Controlled Growing Rods Vs. Posterior Spinal Fusion, Brandon Yoshida, Claudia Leonardi, Jacquelyn Valenzuela-Moss, Lindsay M. Andras, Tyler A. Tetreault, John B. Emans, John T. Smith, Joshua M. Pahys, G. Ying Li, Michael J. Heffernan

School of Public Health Faculty Publications

Purpose: The purpose of this study was to compare the LIV selection in ‘tweener’ patients treated with MCGR or PSF. Methods: A multicenter pediatric spine database was queried for ambulatory patients ages 8–11 years treated by MCGR or PSF with at least 2-year follow-up. The relationship between the LIV and preoperative spinal height, curve magnitude, and implant type were assessed. The relationship between the touched vertebrae (TV), the last substantially touched vertebrae (LSTV), the stable vertebrae (SV), and the LIV were evaluated. Results: One hundred and fifty-nine patients met inclusion criteria. Preoperative curve magnitude was similar between groups (MCGR 68 …

Testing Vivo-Morpholino Mediated Gene Knockdown Of Stat6, Spi1b, And Hnf4Α In Adult Threespine Stickleback, Stella Dipippo

Honors Scholar Theses

The fibrotic immune response to the cestode parasite, Schistocephalus solidus, varies among threespine stickleback populations. Fibrosis suppresses parasite growth but has costly effects on the fish. Previous genomic studies in stickleback have suggested potential roles of Spi1b, STAT6, and HNF4α in modulating fibrosis severity, but there is presently no evidence for this in-vivo. We used antisense vivo-morpholino oligonucleotides (MOs) to attempt to knockdown the expression of each gene in the liver, spleen, and intestine of adult stickleback. Vivo-MOs have been proven effective in other species of teleost fish, as well as in mice and humans, but …

Assessing Leadership In Business: A Critical Investigation Of Jamie Dimon, Conner Delaubell

Honors Scholar Theses

This thesis explores the leadership characteristics of Jamie Dimon, the long-serving CEO of JPMorgan Chase. Dimon's exemplary leadership skills and effective leadership styles have helped the financial firm become the largest bank in the United States. Through a detailed analysis of his background, career milestones, management philosophy, and vision for the future, this paper highlights the positive effect Dimon has had in the modern banking landscape. Additionally, the paper includes areas of leadership improvement, including criticisms of the climate and culture he creates.

Development, Progression, And Mortality Of Suspected Interstitial Lung Disease In Copdgene, Jonathan A Rose, Ann-Marcia C Tukpah, Claire Cutting, Noriaki Wada, Mizuki Nishino, Matthew Moll, Sean Kalra, Bina Choi, David A Lynch, Benjamin A Raby, Ivan O Rosas, Raúl San José Estépar, George R Washko, Edwin K Silverman, Michael H Cho, Hiroto Hatabu, Rachel K Putman, Gary M Hunninghake

Faculty, Staff and Students Publications

Rationale: Some with interstitial lung abnormalities (ILA) are suspected to have interstitial lung disease (ILD), a subgroup with adverse outcomes. Rates of development and progression of suspected ILD and their effect on mortality are unknown. Objectives: To determine rates of development, progression, and mortality in those with suspected ILD and assess effects of individual ILD and progression criteria.

Methods: Participants from COPDGene (Genetic Epidemiology of Chronic Obstructive Pulmonary Disease) with ILA characterization and FVC at enrollment and 5-year follow-up were included. ILD was defined as ILA and fibrosis and/or FVC < 80% predicted. Prevalent ILD was assessed at enrollment and incident ILD and progression were assessed at 5-year follow-up. Computed tomography (CT) progression was assessed visually and FVC decline as relative change. Multivariable Cox regression tested associations between mortality and prevalent ILD, incident ILD, and progression groups.

Measurements and Main Results: Of 9,588 participants at enrollment, 268 …

Mechanical Engineering Insights : Highlights From Final Year Projects 2024

Research Publications (2021 to 2025)

Mechanical Engineering Insights: Highlights from Final Year Project 2024” features a carefully curated collection of outstanding Final Year Projects from the graduating students from the Mechanical Engineering Department, Faculty of Engineering, Universiti Malaya. These projects showcase what the students can achieve after four years of hard work and learning. Each project reflects their creativity and technical skills, showing how they can solve real world problems with practical and sustainable solutions. This compilation is divided into three fundamental themes: Mechanical, Manufacturing, and Materials, representing the core domains of mechanical engineering. The Mechanical theme showcases our students' prowess in applying theoretical knowledge …

Going Generic: A Linguistics Approach To Genericide In Trademark Law, James A. Heilpern, William G. Eggington, Earl Kjar Brown, Zachary D. Smith

BYU Law Review

This Article examines the phenomenon of trademark genericide—the process by which once-protected brand names like “escalator” and “trampoline” lose their legal status by becoming synonymous with entire product categories. Traditional methods used by courts to assess genericide, such as consumer surveys and dictionary definitions, are often criticized for their subjectivity and lack of scientific rigor. In response, this Article introduces corpus linguistics as a more reliable, data-driven alternative for determining whether a trademark has become generic.

By analyzing real-world language usage through large corpora, corpus linguistics can track the public’s shifting perceptions of a trademark over time. Using case studies …

Corpus Linguistics And The Original Meaning Of The Sixth Amendment, Wesley White

BYU Law Review

The Sixth Amendment guarantees the right of an accused to have the assistance of counsel in a criminal prosecution. Put simply, under the U.S. Supreme Court’s current framework, an accused does not enjoy this right until the government has brought a formal charge. Thus, an accused who engages in plea bargaining before being formally charged is not guaranteed the Sixth Amendment right to counsel. Many critics of this framework focus on the purpose of the Sixth Amendment to argue that the right to counsel should be guaranteed in pre-charge plea bargaining. Others point to policy concerns.

This Note is among …

The American Cancer Society National Lung Cancer Roundtable Strategic Plan: Methods For Improving Turnaround Time Of Comprehensive Biomarker Testing In Non-Small Cell Lung Cancer, Sinchita Roy-Chowdhuri, Haresh Mani, Adam H Fox, Anne Tsao, Lynette M Sholl, Farhood Farjah, Bruce E Johnson, Raymond U Osarogiagbon, M Patricia Rivera, Gerard A Silvestri, Robert A Smith, Ignacio I Wistuba

Faculty, Staff and Student Publications

Comprehensive biomarker testing for patients with non-small cell lung cancer is critical for selecting appropriate targeted therapy or immunotherapy. Ensuring timely ordering, processing, and reporting is key to optimizing patient outcomes. However, various factors can prevent or delay patients from being offered the option of treatment selection based on comprehensive biomarker testing. These factors include problems with access to testing, tissue adequacy, turnaround time, and health insurance coverage and billing practices. Turnaround time depends on several logistical and tissue handling factors, which involve institutional policies, processes, resources, testing methodology, and testing algorithms that vary across different practices. In this article, …

In Silico-Predicted Cytokeratin Fragment 21-1 (Cyfra 21-1) Immunogenic Epitopes For The Early Detection Of Nasopharyngeal Carcinoma, Brian Umbu Rezi Depamede, Bachti Alisjahbana, Sulaiman Ngongu Depamede, Sanny Hafidhoh, Siti Nururrohmah, Ilham Ngongu Tryawan, Muhammad Yusuf

Chimica et Natura Acta

Nasopharyngeal Carcinoma, an aggressive cancer in the head and neck region is mostly diagnosed at an advanced stage and thus has a poor prognosis. Cytokeratin Fragment 21-1 (CYFRA 21-1) is one of the oncomarkers discovered in saliva. For developing a diagnostic kit, CYFRA 21-1 antibodies and immunogens are needed. Natural CYFRA 21-1 immunogen is difficult to obtain, so it must be made in-silico using bioinformatics. We aim to predict CYFRA 21-1 immunogenic epitope to produce antibodies polyclonal against CYFRA 21-1, which can be used to develop NPC diagnostics. The immunogenic epitopes were predicted and chosen based on antigenicity, surface accessibility, …

Theory And Algorithms To Learn, Propagate, And Exploit Uncertainty For Stochastic Optimal Control Of Dynamical Systems, Vignesh Sivaramakrishnan

Electrical and Computer Engineering ETDs

Non-Gaussian uncertainty frequently arises in learning and control problems involving stochastic dynamical systems, particularly in autonomous vehicles, UAVs, satellites, and robotics. In this dissertation, we propose a new framework that leverages characteristic functions that provides a frequency-domain representation of random variables. The dissertation is structured into three key areas. First, we address model-based stochastic optimal control for linear systems with non-Gaussian noise, demonstrating that characteristic functions can be used to enforce chance constraints and control systems toward desired distributions. Second, we explore data-driven stochastic control, utilizing empirical characteristic functions to handle systems with unknown disturbances. In addition, we derive several …

Conceptualization, Measurement, And Contributors To Participation Among People Living With Parkinson’S Disease, Moon Young Kim

WUSM Theses and Dissertations – All Programs

Participation is a key outcome of rehabilitation and key to successful aging. Individuals with Parkinson’s disease (PD) often experience significant challenges in maintaining participation in meaningful activities and roles. This dissertation examines the influence of living with PD on participation by integrating findings from three studies: a systematic review, a cross-sectional study, and a longitudinal study.

The systematic review synthesized the existing quantitative research on participation in people with PD, revealing inconsistencies in the conceptualization of participation. While the evaluation tools aimed at assessing participation in PD showed acceptable coverage of domains of participation, the assessment of the aspects of …

Turn On The Lights! Building The Evidence Base To Inform Cancer Of Sexual And Gender Minority Groups, Shine Chang

Faculty, Staff and Student Publications

No abstract provided.

The American Cancer Society National Lung Cancer Roundtable Strategic Plan: Advancing Comprehensive Biomarker Testing In Non-Small Cell Lung Cancer, Adam H Fox, Raymond U Osarogiagbon, Farhood Farjah, James R Jett, Bruce E Johnson, M Patricia Rivera, Robert A Smith, Ignacio I Wistuba, Gerard A Silvestri

Faculty, Staff and Student Publications

Comprehensive biomarker testing is a crucial requirement for the optimal treatment of advanced-stage non-small cell lung cancer (NSCLC), with emerging relevance in the adjuvant treatment setting. To advance its goal of ensuring optimal therapy for persons diagnosed with lung cancer, the American Cancer Society National Lung Cancer Roundtable (ACS NLCRT) held The Summit on Optimizing Lung Cancer Biomarkers in Practice in September 2020 to align its partners toward the goal of ensuring comprehensive biomarker testing for all eligible patients with NSCLC. The ACS NLCRT's Strategic Plan for Advancing Comprehensive Biomarker Testing in NSCLC, a product of the summit, comprises actions …

The Microrna Mir-223 Constrains Colitis-Associated Tumorigenesis By Limiting Myeloid Cell Infiltration And Chemokine Expression, Ciara L Flynn, Gary E Markey, Viola Neudecker, Charlotte Farrelly, Glenn T Furuta, Holger K Eltzschig, Joanne C Masterson, Eóin N Mcnamee

Faculty, Staff and Student Publications

Aberrant intestinal inflammation plays a critical role in the development of colitis-associated colorectal cancer (CAC), yet the mechanisms controlling tumor development by the myeloid immune compartment are not fully understood. Although altered microRNA expression is observed in CAC, it is also unclear how myeloid-specific microRNAs impact the inflammatory process that underpins the continuum from ulcerative colitis to tumorigenesis. In this study, we report that miR-223 acts to limit myeloid-driven inflammation in the azoxymethane (AOM)-dextran sodium sulfate (DSS) model of CAC in mice. In this model, miR-223-/y mice present with significantly larger tumors with an enhanced proliferative signature. Immunoprofiling showed that …

Farmers’ Decision Processes About Biocontrol Innovation Adoption: Dynamics Surrounding Push-Pull Technology In Western Kenya, Olufemi Samson Adesina, Stephen Whitfield, Susannah M. Sallu, Steven M. Sait, Jimmy Pittchar

All Peer-Reviewed Publications

Smallholder farmers in sub-Saharan Africa (SSA) face increasing challenges from pests and climate change, among other issues. In response to these challenges, international agricultural research for development (R4D) investment is often focused on developing and scaling up techniques and technologies that bolster resilience. However, such approaches are often technocentric and follow linear assumptions of innovation diffusion and adoption, which overlook the complex realities that influence smallholder farmers’ dynamic decisions and engagement with novel techniques. This study used qualitative ethnographic methods to explore the experiences, knowledge construction, motivations, and decision-making of farmers in Western Kenya regarding the extensively researched push-pull technology …

Leveling Up: Students' Perceptions Of Digital Game-Based Learning, Maryan Al-Houssein

Seton Hall University Dissertations and Theses (ETDs)

This case study investigated middle school students’ perceptions of digital game-based learning (DGBL) in the classroom, focusing on engagement, motivation, and academic achievement. Using Piaget’s (1962) Constructivist Learning Theory as a framework, the research examined the influence of interactive digital games on students’ educational experiences. A qualitative study was utilized, using Likert scale surveys and open-ended questions to gather rich, descriptive data from students across grades 6-8. The findings revealed three primary themes: (1) Engagement and Interest, with students reporting increased enjoyment and interactivity in learning; (2) Motivation and Focus, indicating that competitive elements and rewards in games encourage student …

Trastuzumab Deruxtecan With Nivolumab In Her2-Expressing Metastatic Breast Or Urothelial Cancer: Analysis Of The Phase Ib Ds8201-A-U105 Study., E Hamilton, Galsky Md, S Ochsenreither, Conte G Del, M Martín, De Miguel Mj, Yu Ey, Anja Williams, M Gion, Tan Ar, L Agrawal, A Rutten, Machiels Jp, S Hurvitz, Philip Debruyne

School of Nursing and Midwifery

Purpose:This multicenter phase Ib study investigated trastuzumab deruxtecan (T-DXd) plus nivolumab in patients with HER2-expressing metastatic breast cancer (mBC) and metastatic urothelial cancer (mUC).Patients and Methods:Part 1 determined the recommended dose for expansion of T-DXd plus nivolumab. Part 2 evaluated efficacy and safety; the primary endpoint was confirmed objective response rate by independent central review.Results:In part 1, seven patients with mBC were enrolled and received T-DXd 3.2 mg/kg (four patients) or 5.4 mg/kg (three patients) plus nivolumab. The recommended dose for expansion for T-DXd was 5.4 mg/kg plus nivolumab 360 mg intravenously every 3 weeks. In part 2, 32 patients …

Mrs. Lucille Stidem Hill

African American Funeral Programs

Mrs_Lucille_Stidem_Hill.pdf - Funeral program for Lucille Hill

Global Impact Of Aging On The Hemodynamic Response Function In The Gray Matter Of Human Cerebral Cortex, Nooshin J Fesharaki, Amanda Taylor, Keisjon Mosby, Ruosha Li, Jung Hwan Kim, David Ress

Faculty, Staff and Students Publications

In functional magnetic resonance imaging, the hemodynamic response function (HRF) is a stereotypical response to local changes in cerebral hemodynamics and oxygen metabolism due to briefly (< 4 s) evoked neural activity. Accordingly, the HRF is often used as an impulse response with the assumption of linearity in data analysis. In cognitive aging studies, it has been very common to interpret differences in brain activation as age-related changes in neural activity. Contrary to this assumption, however, evidence has accrued that normal aging may also significantly affect the vasculature, thereby affecting cerebral hemodynamics and metabolism, confounding interpretation of fMRI cognitive aging studies. In this study, use was made of a multisensory task to evoke the HRF in ~87% of cerebral cortex in cognitively intact adults with ages ranging from 22 to 75 years. This widespread activation enabled us to investigate age trends in the spatial distributions of HRF characteristics within the majority of cortical gray matter, which we termed as global age trends. The task evoked both positive and negative HRFs, which were characterized using model-free parameters in native-space coordinates. We found significant global age trends in the distributions of HRF parameters in terms of both amplitudes (e.g., peak amplitude and contrast-to-noise ratio) and temporal dynamics (e.g., full-width-at-half-maximum). Our findings offer insight into how age-dependent changes affect neurovascular coupling and show promise for use of HRF parameters as non-invasive indicators for age-related pathology.

The State Of (Mis) Trust: Human-Centered Technology Development & Implementation In Intensive Mental Health Settings, Jessa Lin Westheimer, Ryan P Smith, Peter Iacobelli, Hyuntaek Oh, Lacey Tezino, Raheela Khan, Jared Broussard, Gordon Meltzer, Nadine Obeid, Stephanie Cunningham, Robert J Boland, Michelle A Patriquin

Staff and Researcher Publications

Innovative technology-based solutions in mental healthcare promise significant improvements in care quality and clinical outcomes. However, their successful implementation is profoundly influenced by the levels of trust patients hold toward their treatment providers, organizations, and the technology itself. This paper delves into the complexities of building and assessing patient trust within the intensive mental health care context, focusing on inpatient settings. We explore the multifaceted nature of trust, including interpersonal, institutional, and technological trust. We highlight the crucial role of therapeutic trust, which comprises both interpersonal trust between patients and providers, and institutional trust in treatment organizations. The manuscript identifies …

Modern Agricultural Servitude: The Modern Farm Worker Experience In The Salinas Valley, Jesus E. Tavarez

Chicana and Chicano Studies ETDs

The prevailing narrative in Chicanx studies focuses on the historical labor activism of the United Farm Workers (UFW) in the 1960s and ‘70s. I am particularly interested in examining the contemporary campesino experience in the Salinas Valley by discussing the history behind Mexican cheap labor, low wages, exploitive work conditions with inadequate healthcare, agrochemical exposure, and historical consciousness of farm workers. I will argue that farm workers are in dire need of a migratory reform as an approach to improve the working conditions of farm workers throughout California. This research aims to shed light on how the multi-billion-dollar agribusiness industry …

Maternal Adverse Childhood Experiences And Infant Visual-Limbic White Matter Development, Catherine H. Demers, Benjamin L. Hankin, Mercedes Hoeflich Haase, Erin Todd, M. Camille Hoffman, C. Neill Epperson, Martin A. Styner, Elysia Poggi Davis

Psychology: Faculty Scholarship

Background

Maternal adverse childhood experiences (ACEs) are robust predictors of mental health for both the exposed individual and the next generation; however, the pathway through which such intergenerational risk is conferred remains unknown. The current study evaluated the association between maternal ACEs and infant brain development, including an a priori focus on circuits implicated in emotional and sensory processing.

Methods

The sample included 101 mother-infant dyads from a longitudinal study. Maternal ACEs were assessed with the Adverse Childhood Questionnaire dichotomized into low (0 or 1) and high (≥2) groups. White matter microstructure, as indexed by fractional anisotropy (FA), was assessed …

The Role Of Nutrient Solutions On Phosphate-Solubilizing Bacteria Population, Phosphorus Availability, Phosphorus Uptake, Growth And Yield Of Red Chili (Capsicum Annuum L.), Betty Natalie Fitriatin, Raden Faqih Hilmiy Ghifari, Emma Trinurani Sofyan, Fitri Widiantini, Hanif Fakhrurroja, Tualar Simarmata

Jurnal Kultivasi

Red chili consumption in Indonesia has increased every year. However, with large chili production to meet large consumption, land conversion for various purposes has reduced the harvested area. The efforts to increase the harvested area of chili using Inceptisols soil by providing nutrient solutions to overcome the infertility of the soil using its nutrients. This experiment aims to determine the effect of nutrient solution application on the population of phosphate-solubilizing bacteria, phosphorus availability, phosphorus uptake, growth, and yield of Red Chili (Capsicum annuum L.) in Inceptisols. The experiment was conducted from August 2023 to February 2024 at Ciparanje Experimental Field, …

A Practical Clinical Approach To Navigate Pulmonary Embolism Management: A Primer And Narrative Review Of The Evolving Landscape, Kevin Benavente, Bradley Fujiuchi, Hafeez Ul Hassan Virk, Pavan K Kavali, Walter Ageno, Geoffrey D Barnes, Marc Righini, Mahboob Alam, Rachel P Rosovsky, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Advances in imaging, pharmacological, and procedural technologies have rapidly expanded the care of pulmonary embolism. Earlier, more accurate identification and quantification has enhanced risk stratification across the spectrum of the disease process, with a number of clinical tools available to prognosticate outcomes and guide treatment. Direct oral anticoagulants have enabled a consistent and more convenient long-term therapeutic option, with a greater shift toward outpatient treatment for a select group of low-risk patients. The array of catheter-directed therapies now available has contributed to a more versatile and nuanced armamentarium of treatment options, including ultrasound-facilitated thrombolysis and mechanical thrombectomy. Research into supportive …

A Practical Clinical Approach To Navigate Pulmonary Embolism Management: A Primer And Narrative Review Of The Evolving Landscape, Kevin Benavente, Bradley Fujiuchi, Hafeez Ul Hassan Virk, Pavan K Kavali, Walter Ageno, Geoffrey D Barnes, Marc Righini, Mahboob Alam, Rachel P Rosovsky, Chayakrit Krittanawong

2020-Current year OA Pubs

Advances in imaging, pharmacological, and procedural technologies have rapidly expanded the care of pulmonary embolism. Earlier, more accurate identification and quantification has enhanced risk stratification across the spectrum of the disease process, with a number of clinical tools available to prognosticate outcomes and guide treatment. Direct oral anticoagulants have enabled a consistent and more convenient long-term therapeutic option, with a greater shift toward outpatient treatment for a select group of low-risk patients. The array of catheter-directed therapies now available has contributed to a more versatile and nuanced armamentarium of treatment options, including ultrasound-facilitated thrombolysis and mechanical thrombectomy. Research into supportive …

Impact Of Site-Specific Conjugation Strategies On The Pharmacokinetics Of Antibody Conjugated Radiotherapeutics, Ábel Nagy, David Ulmert, Wahed Zedan, Claire M Storey, Julie Park, Susanne Geres, Katharina Lückerath, Kjell Sjöström, Hadis Westin, Norbert Peekhaus, Daniel Lj Thorek, Amelie Eriksson Karlström, Mohamed Altai

2020-Current year OA Pubs

Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to monoclonal antibodies (mAbs) is typically achieved by applying non-site-specific labelling techniques. With the ambition of reducing variability, increasing labelling efficacy and stability, several site-specific conjugation strategies have been developed in recent years for toxin- and fluorophore-mAb conjugates. In this study, we studied two site-specific labelling strategies for the conjugation of the macrocyclic chelating agent, DOTA, to the anti-Leucine Rich Repeat Containing 15 (LRRC15) mAb DUNP19. Specifically, one approach utilized a DOTA-bearing peptide (FcIII) with a strong affinity for the fragment …

Top Ten Epilepsy Research Priorities: A Uk Priority Setting Partnership, Rohit Shankar

Peninsula Medical School

Purpose: Research into epilepsy has experienced decades of chronic underfunding compared to other neurological conditions despite its prevalence and seriousness. To evidence the need for greater investment, the Epilepsy Research Institute (formerly Epilepsy Research UK) funded, led and managed a James Lind Alliance (JLA) Priority Setting Partnership (PSP). This “industry standard” methodology brings together healthcare professionals, patients, carers and patient group representatives to identify and prioritise research uncertainties within a defined area of health or care.Methods: The UK Epilepsy PSP is a once-in-a-generation, national consensus that collated and ranked the research priorities of the UK epilepsy and associated condition community. …

Biomedical Potential Of Natural Products From Selected Tanzanian Flora: A Review, Stephen S. Nyandoro, Joan J.E. Munissi

Tanzania Journal of Science

Natural products have been used for treatment of various diseases for thousands of years and served as sources of drug lead compounds for the improvement of livelihood. This paper presents a review on the biomedical potentials of selected natural products isolated from eight plant species indigenous to Tanzania. The review covers research work published between 2010 and 2023, and identifies 33 natural products with different pharmacological properties from Tanzanian plants. These bioactive natural products are discussed with other similar compounds isolated elsewhere from the same or different plant species to get further insights on the potential application in modern medicine …