Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (27180)
- Social and Behavioral Sciences (12272)
- Medical Specialties (9468)
- Life Sciences (8347)
- Education (8009)
-
- Medical Sciences (6567)
- Law (5172)
- Arts and Humanities (4732)
- Physical Sciences and Mathematics (4335)
- Public Health (4172)
- Psychology (3275)
- Engineering (2916)
- Oncology (2772)
- Diseases (2656)
- Biomedical Informatics (2632)
- Nursing (2503)
- Bioinformatics (2246)
- Higher Education (2226)
- Business (2171)
- Sociology (2099)
- Medical Education (1742)
- Medical Genetics (1631)
- Public Affairs, Public Policy and Public Administration (1584)
- Mental and Social Health (1566)
- Rehabilitation and Therapy (1461)
- Environmental Sciences (1333)
- Genetic Phenomena (1273)
- Health and Physical Education (1101)
- Pediatrics (1083)
- Computer Sciences (1070)
- Institution
-
- The Texas Medical Center Library (5980)
- University of South Florida (1866)
- Washington University School of Medicine (1707)
- Walden University (1580)
- University of Montana (1502)
-
- Sigma Theta Tau International Honor Society of Nursing (1285)
- Liberty University (1233)
- University of Kentucky (1216)
- Chulalongkorn University (1215)
- University of Texas Rio Grande Valley (1091)
- Thomas Jefferson University (987)
- University of Nebraska - Lincoln (985)
- University of Plymouth (838)
- University of South Carolina (784)
- Western Kentucky University (761)
- University of New Hampshire (738)
- Universitas Indonesia (733)
- Advocate Health - Midwest (715)
- Edith Cowan University (711)
- Utah State University (705)
- Nova Southeastern University (674)
- University of Arkansas, Fayetteville (668)
- American Dental Association (630)
- HCA Healthcare (607)
- Portland State University (573)
- LSU Health New Orleans (568)
- Brigham Young University (559)
- City University of New York (CUNY) (553)
- University of New Mexico (547)
- Louisiana State University (532)
- Keyword
-
- Humans (5637)
- Female (2809)
- Male (2457)
- Animals (1647)
- Adult (1490)
-
- ICTS (Institute of Clinical and Translational Sciences) (1421)
- Middle Aged (1398)
- Aged (1185)
- Mice (1128)
- COVID-19 (887)
- Child (740)
- Mental health (708)
- Education (674)
- Adolescent (663)
- United States (560)
- Retrospective Studies (490)
- Young Adult (454)
- Depression (425)
- Neoplasms (399)
- Treatment Outcome (398)
- Pregnancy (363)
- Biomarkers (357)
- Health (356)
- Anxiety (347)
- Infant (346)
- Risk Factors (342)
- Machine learning (340)
- Mutation (336)
- Tumor (328)
- Artificial intelligence (325)
- Publication
-
- Faculty, Staff and Student Publications (3558)
- Faculty, Staff and Students Publications (1902)
- Theses and Dissertations (1763)
- 2020-Current year OA Pubs (1690)
- Walden Dissertations and Doctoral Studies (1508)
-
- University of Montana Course Syllabi, 2021-2025 (1149)
- Doctoral Dissertations and Projects (937)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (813)
- The Auk (791)
- Dissertations (765)
- Electronic Theses and Dissertations (690)
- Research outputs 2022 to 2026 (660)
- Faculty Publications (630)
- Leadership Connection (551)
- International Journal of Exercise Science: Conference Proceedings (524)
- Faculty Scholarship (491)
- Historical Documents - Combined (417)
- Honors Theses (393)
- Theses (354)
- Silver Bow Creek/Butte Area Superfund Site (323)
- Articles (317)
- School of Medicine Faculty Publications (295)
- Research Symposium (277)
- Master's Theses (271)
- USF Tampa Graduate Theses and Dissertations (258)
- Patient Education Projects (255)
- 2024 Decisions (251)
- DRS Biennial Conference Series (249)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (236)
- International Journal of Physical Activity and Health (233)
- Publication Type
Articles 1921 - 1950 of 79573
Full-Text Articles in Entire DC Network
Change Of Carbohydrate Concentration In Reactors From Spring To Fall 2022 After Refrigeration, Amanda Ventura
Change Of Carbohydrate Concentration In Reactors From Spring To Fall 2022 After Refrigeration, Amanda Ventura
The Journal of Purdue Undergraduate Research
No abstract provided.
Relocation Incentives In Alaska; Or, The Call Of The Wild And Transfer Payments, Nathan Miller
Relocation Incentives In Alaska; Or, The Call Of The Wild And Transfer Payments, Nathan Miller
The Journal of Purdue Undergraduate Research
No abstract provided.
Orange Corn–Based Diet Improves Total Antioxidant Capacity In Layer Pullets Compared To Traditional Yellow Corn Diets, Serena Wesley
Orange Corn–Based Diet Improves Total Antioxidant Capacity In Layer Pullets Compared To Traditional Yellow Corn Diets, Serena Wesley
The Journal of Purdue Undergraduate Research
No abstract provided.
Where To Build Food Banks: A Machine Learning Approach, Gavin Ruan
Where To Build Food Banks: A Machine Learning Approach, Gavin Ruan
The Journal of Purdue Undergraduate Research
Over 44 million Americans currently suffer from food insecurity, of whom 13 million are children. Food insecurity has been shown to cause a wide range of both physical and developmental issues. Across the United States, thousands of food banks and pantries serve as vital sources of food and other forms of aid for food-insecure families. By optimizing food bank locations, food banks and their resources would become more accessible to families who desperately require it. The aim of this paper is to build a machine learning framework that is able to optimize food bank locations and to consider factors such …
Security At Too High An Environmental Cost?: The European Union's Energy Independence Strategy And Its Environmental Implications For Air Quality In Poland And Hungary, Stephanie P. Peterson
Security At Too High An Environmental Cost?: The European Union's Energy Independence Strategy And Its Environmental Implications For Air Quality In Poland And Hungary, Stephanie P. Peterson
The Journal of Purdue Undergraduate Research
After Russia’s invasion of Ukraine in 2022, the European Union worked to secure liquified natural gas (LNG) deals with third countries to abolish its dependence on Russian gas. In this article, I sought to determine the environmental implications of the European Union’s new LNG deals on the air quality in Hungary and Poland, two former communist states. Despite LNG being a cleaner fossil fuel, I hypothesized that it posed a threat to Hungary’s and Poland’s air quality as both countries endured rapid industrialization under Soviet control that forwent environmental protections. To prove this, I used qualitative data from before the …
Effect Of Developmental Manganese Exposure On The Locomotor Behavior Of Zebrafish Larvae, Breeann Mild
Effect Of Developmental Manganese Exposure On The Locomotor Behavior Of Zebrafish Larvae, Breeann Mild
The Journal of Purdue Undergraduate Research
Manganese, an essential trace mineral, plays crucial roles in various physiological processes within living organisms. However, excessive exposure to manganese can lead to toxicity, particularly impacting the central nervous system. This study aimed to assess the impact of manganese exposure on locomotor behavior during early development using zebrafish (Danio rerio) as a model organism. Zebrafish embryos at 1–2 hours post fertilization (hpf) were exposed to five different concentrations of manganese chloride (0, 0.01, 0.05, 0.1, or 0.5 mM) until 120 hpf. Locomotor behavior was assessed using the visual motor response assay, measuring parameters such as total distance moved, velocity, and …
Predictive Maintenance Analysis Of Turbofan Engine Sensor Data, Stanley A. Melkumian
Predictive Maintenance Analysis Of Turbofan Engine Sensor Data, Stanley A. Melkumian
The Journal of Purdue Undergraduate Research
Predictive maintenance in aviation and aerospace applications is among the most explored problems in machine learning (ML) and artificial intelligence (AI), and datasets such as NASA’s C-MAPPS turbofan engine degradation simulation data have proven invaluable, helping researchers explore numerous questions on engine performance, maintenance, and failure. The purpose of this study was to extend the current research on predicting the remaining useful life (RUL) of engines and their risk classification. Starting with simple yet under-investigated nonlinear survival and random forest models, the analysis implemented eXtreme Gradient Boosting (XGBoost) and long short-term memory (LSTM) from TensorFlow’s Keras library. For both regression …
The Influence Of Soil Properties And Land Management On Soil Porewater Chemistry, Bethany Kettleborough
The Influence Of Soil Properties And Land Management On Soil Porewater Chemistry, Bethany Kettleborough
The Journal of Purdue Undergraduate Research
Soil water dynamics influence vegetation health, soil geochemical reactions, and stream chemistry. Water dynamics can be controlled by soil type and land management. It is important to understand water movement due to its influence on soil weathering, microbial activity, and nutrient transport. Water movement can be investigated using water stable isotope variability as a tracer. The purpose of this ongoing study was to analyze stable isotopes and dissolved ions in prairie and agricultural land management sites in Nebraska and Illinois. Prairies typically contain deep-rooted grasses, while agricultural lands contain shallow-rooted row crops. Root depth is considered a major control on …
Coded Bias In Applicant Tracking Systems, Prithvi Dhanabal, Emily Hao
Coded Bias In Applicant Tracking Systems, Prithvi Dhanabal, Emily Hao
The Journal of Purdue Undergraduate Research
This Tech Justice Lab project explored potential hiring discrimination against transgender and gender-nonconforming job applicants in the hiring process by evaluating the impact of including pronouns in résumés submitted to an applicant tracking system (ATS) platform. The research team began by collecting background information regarding existing discrimination against transgender job applicants and how ATS platforms can reflect and magnify existing biases in the hiring process. A “sock puppet” audit was then conducted by submitting fake user résumés to test the platform’s response. The chosen platform was Jobscan, an applicant-facing software claiming the ability to simulate a résumé review by major …
Preliminary Checklist Of Amphipod Crustaceans From Sapelo Island, Ga, Abigail Dugger*, Kristine N. White Ph.D.
Preliminary Checklist Of Amphipod Crustaceans From Sapelo Island, Ga, Abigail Dugger*, Kristine N. White Ph.D.
Georgia Journal of Science
Amphipods belonging to the subphylum Crustacea inhabit many aquatic habitats, and they can often inform scientists and researchers about various environmental conditions, acting as biological indicators, yet documentation of amphipod species is lacking in the state of Georgia. During this study amphipods were collected from around Sapelo Island, GA, imaged, and identified. A preliminary checklist and identification key to Sapelo Island amphipods is provided. This checklist and key will be useful for researchers and citizen scientists alike, for monitoring the health of the environment, surveying biodiversity, and for use in other applied studies.
Embodied Cognition And Teaching Stem: Tenets To Explain And Enhance A Middle School Science Project, Jonathan E. Roberts, Joshua L. Williams, Robert A. Hodgdon, Caroline Payne, Gabriela Ruiz Emmanuelli
Embodied Cognition And Teaching Stem: Tenets To Explain And Enhance A Middle School Science Project, Jonathan E. Roberts, Joshua L. Williams, Robert A. Hodgdon, Caroline Payne, Gabriela Ruiz Emmanuelli
Current Issues in Middle Level Education
STEM pedagogy is a popular area for research and discussion. The empirical literature on this topic supports a variety of approaches (e.g., inquiry-based) to help instructors spark student interest create an effective learning environment, and foster long-term retention and transfer of information related to STEM topics. One potential approach is to use tenets of embodied cognition, in which behavior and cognition emerge out of real-time sensorimotor behavior of the individual situated within a particular context, to implement strategies to enhance STEM pedagogy. We applied the six lessons of embodied cognition to understand the beneficial aspects of a middle-school project on …
"Wedded In The Association": Heteroglossic Form And Fragmentary Histiography In Nick Joaquin's Almanac For Manileños, Vincenz Serrano
"Wedded In The Association": Heteroglossic Form And Fragmentary Histiography In Nick Joaquin's Almanac For Manileños, Vincenz Serrano
Kritika Kultura
Almanac for Manileños (1979) by Nick Joaquin (1917-2004) is “a calendar, a weather chart, a sanctoral, a zodiac guide, and a mini encyclopedia on the world of the Manileño.” Undergirded by Mikhail Bakhtin’s concept of heteroglossia, Walter Benjamin’s montage method in writing history, and Reynaldo Ileto’s notion of non-linear emplotment, the essay engages with the Almanac’s calendars and essays and offers four claims. Firstly, although multiple genres embedded in the Almanac—which include, apart from the abovementioned, horoscopes, recipes and light verse—stratify the text, temporal associativeness offers a sense of cohesion. Secondly, the formal strategy of the calendars—typified by correspondence and …
In A Dance With Words: Dance Movement Psychotherapy And Ontological Inquiry, Diana Mota
In A Dance With Words: Dance Movement Psychotherapy And Ontological Inquiry, Diana Mota
Turning Toward Being: The Journal of Ontological Inquiry in Education
This article explores intersections between dance, psychotherapy, phenomenology, and ontology, addressing how both verbal and non-verbal language enact ways of being in the world. The main aim is to investigate potential contributions of ontological inquiry to the practice of dance psychotherapy, to thereby strengthen the therapeutic relationship. Drawing on her practical experience and theory building in dance and dance therapy, the author presents clinical vignettes from a session as a laboratory to elaborate an ontological-phenomenological model. She concludes by clearly advocating for further exploration of these intersections and argues these fields are mutually enriching and complementary.
Making A Personal Connection Brings Back The Magic, Don Sessions
Making A Personal Connection Brings Back The Magic, Don Sessions
Turning Toward Being: The Journal of Ontological Inquiry in Education
In this age of technology with its concerns for efficiency and resources the practice of medicine and the relationship between doctors and patients is under assault. Using the doctor-patient relationship as a model to address this concern the author claims that making a personal connection between doctors and patients at the level of their shared humanity produces synchronous beneficial results. Further, this personal connection can facilitate magic, an experience where a specialized type of language and listening allow for unpredictable and unexpected results.
Editorial Statement: Volume 2, Issues 1 And 2, Carolyne J. White
Editorial Statement: Volume 2, Issues 1 And 2, Carolyne J. White
Turning Toward Being: The Journal of Ontological Inquiry in Education
No abstract provided.
Come To The Lake: Harnessing Academic Resources And Empowering Students To Transform Clinical Landscapes., Natalie A. Perkins, Natalie Loera, Issa Flores, Rajvinder Bains, Divya Desai, Carlin Reaume
Come To The Lake: Harnessing Academic Resources And Empowering Students To Transform Clinical Landscapes., Natalie A. Perkins, Natalie Loera, Issa Flores, Rajvinder Bains, Divya Desai, Carlin Reaume
Pacific Journal of Health
In higher education, the relationship between students and academic resources plays a pivotal role in shaping both individual growth and the broader landscape of learning. This article explores how educators, particularly in occupational therapy, have designed rich academic environments—likened to lakes brimming with resources—that provide students with opportunities for deep engagement. However, to truly harness these resources, students must be empowered as active participants in shaping the academic and clinical landscapes. The article advocates for a reimagining of academia, where students contribute to the knowledge ecosystem through research, innovation, and experiential learning, ensuring that education becomes a dynamic, collaborative process. …
Secure Healthcare Systems And Big Data: A Bibliometrics Analysis, Rasha Talal Hameed, Saad Ahmed Dheyab, Saba Abdulbaqi Salman, Ahmed Hussein Ali, Omar Abdulwahabe Mohamad
Secure Healthcare Systems And Big Data: A Bibliometrics Analysis, Rasha Talal Hameed, Saad Ahmed Dheyab, Saba Abdulbaqi Salman, Ahmed Hussein Ali, Omar Abdulwahabe Mohamad
Iraqi Journal for Computer Science and Mathematics
This study conducts a bibliometrics analysis of research on secure healthcare systems and big data, aiming to identify trends, key contributors, and thematic areas within the field. By examining a comprehensive database of academic publications, we highlight the evolution of research from foundational concepts to contemporary innovations in data security and privacy management in healthcare. Key metrics such as publication volume, citation impact, and co-authorship networks are analyzed to uncover the most influential authors and institutions. Additionally, we explore the integration of big data analytics in enhancing healthcare delivery while addressing security challenges. The findings provide valuable insights for researchers …
Sneaking Into The Philippines, Along The Rivers Of Babylon: An Intervention Into The Language Question, E. San Juan Jr.
Sneaking Into The Philippines, Along The Rivers Of Babylon: An Intervention Into The Language Question, E. San Juan Jr.
Kritika Kultura
The following are remarks made on 12 March 2008 at the launching of Balikbayang Sinta: An E. San Juan Reader published by Ateneo de Manila UP. Here the author puts forward seven theses through which the contentious “language question” may be reexamined, especially as it touches on issues of national solidarity.
The Condition Of Filipino Americanism: Global Americana As A Relation Of Death, Dylan Rodríguez
The Condition Of Filipino Americanism: Global Americana As A Relation Of Death, Dylan Rodríguez
Kritika Kultura
At the nexus of a prevailing Filipino-American discourse that celebrates the Filipino-American as a cooperative participant in the United States nation-building project sits an “unnamable violence” that masks the genocidal preconditions of “multiculturalist” white supremacy, to which this discourse unwittingly subscribes. The article explores the beginnings and development of this discourse, and the workings of American white supremacy in naturalizing relations of death between itself and its “others.” The article ends with a reflection on how “natural” disasters like Hurricane Katrina and the eruption of Mt. Pinatubo become means of legitimizing discourses that reinforce white invulnerability vis-à-vis disposability of non-white …
Sneaking Into The Philippines, Along The Rivers Of Babylon: An Intervention Into The Language Question, E. San Juan Jr.
Sneaking Into The Philippines, Along The Rivers Of Babylon: An Intervention Into The Language Question, E. San Juan Jr.
Kritika Kultura
The following are remarks made on 12 March 2008 at the launching of Balikbayang Sinta: An E. San Juan Reader published by Ateneo de Manila UP. Here the author puts forward seven theses through which the contentious “language question” may be reexamined, especially as it touches on issues of national solidarity.
The Condition Of Filipino Americanism: Global Americana As A Relation Of Death, Dylan Rodríguez
The Condition Of Filipino Americanism: Global Americana As A Relation Of Death, Dylan Rodríguez
Kritika Kultura
At the nexus of a prevailing Filipino-American discourse that celebrates the Filipino-American as a cooperative participant in the United States nation-building project sits an “unnamable violence” that masks the genocidal preconditions of “multiculturalist” white supremacy, to which this discourse unwittingly subscribes. The article explores the beginnings and development of this discourse, and the workings of American white supremacy in naturalizing relations of death between itself and its “others.” The article ends with a reflection on how “natural” disasters like Hurricane Katrina and the eruption of Mt. Pinatubo become means of legitimizing discourses that reinforce white invulnerability vis-à-vis disposability of non-white …
Virtual Reality Exposure Therapy For Social Anxiety In Adolescents, April Fohrman
Virtual Reality Exposure Therapy For Social Anxiety In Adolescents, April Fohrman
Counselor Education Capstones
Exposure therapy has been around for decades and is still proving to be a robust, evidence-based treatment modality for several psychological issues. Imaginal exposure (vividly imagining a feared object, situation, or activity) and in vivo (directly experiencing the real fear or situation) are the traditional modes of exposure intervention. Although these treatments have shown that they work, they can also be time-consuming, expensive, or even impossible to replicate. A newer exposure therapy combines traditional imaginal therapy with in vivo therapy, but virtually.
This combination creates a middle ground where exposures to situations or fears can be increased or decreased virtually …
Assessing Risks Of Atypical Sexually Violent Offenders, Lesli Mattheus
Assessing Risks Of Atypical Sexually Violent Offenders, Lesli Mattheus
Master of Arts in Human Services
Forensic behavioral health research over the past few decades has revealed the complexities of assessing sexually violent offenders (SVOs). Risk assessments play a critical role in determining penalties and treatment, evaluating recidivism risk, and guiding interventions. However, most research has focused on adult male offenders, leaving a significant gap in understanding less common offender types, such as women, juveniles, and pedophiles or child sexual abusers. Gender biases and underreporting limit the understanding of women offenders, while juveniles face challenges like substance use disorders and mental health issues. Structured clinical judgment is a key method for assessing SVO risk, but forensic …
A Latent Profile Analysis Of High-Risk Children's Problematic Sexual Behavior, Claudia Campbell
A Latent Profile Analysis Of High-Risk Children's Problematic Sexual Behavior, Claudia Campbell
Dissertations
As research and intervention regarding children’s problematic sexual behavior (PSB) have broadly defined PSB, including all forms of developmentally atypical sexual behavior and all potential etiological factors, limited work to date has identified subtypes or unique patterns of PSB. The aim of the current study was to examine the presence of unique patterns of PSB and etiological factors among high-risk children utilizing latent profile analysis (LPA) based on children’s self-focused PSB, interpersonal PSB (IPSB), maltreatment factors, co-occurring symptoms, adaptive functioning, and family functioning. The present study included 689 8-year-old children (50.1% male, 50.2% Black) with potential PSB and their caregivers …
Faculty Senate Executive Committee Agenda December 16, 2024, Utah State University
Faculty Senate Executive Committee Agenda December 16, 2024, Utah State University
Faculty Senate & Faculty Senate Executive Committee
- Call to Order
- Approval of Minutes
- University Business
- Faculty Senate Business
- Information
- EPC Report
- Policy 301
- Policy 368
- Report
- Council on Teacher Education Annual Report
- Scholarship Annual Report
- Old Business
- New Business
- Adjourn: 4:30
The Doing, Being, Becoming, And Belonging Of Intergenerational Collective Occupations, Gladys Garcia, Jazminne Orozco-Arteaga
The Doing, Being, Becoming, And Belonging Of Intergenerational Collective Occupations, Gladys Garcia, Jazminne Orozco-Arteaga
Fall 2024 OTD Capstone Symposium
Background: Older adults have been globally recognized as a vulnerable population. Literature has indicated that intergenerational engagement can decrease social isolation for older adults, but there is a gap in understanding intergenerational co-occupational engagement and how these engagements can improve quality of life and fulfillment of self-identity. The purpose of this qualitative research study was to generate knowledge of how relationships and occupations performed with individuals from a younger generation impacted sense of well-being. Through the lens of Doing, Being, Becoming and Belonging (Wilcock, 2006), the study sought to increase understanding of this lived experience to promote intergenerational practice within …
Phytoplankton Monitoring In Gulf Of Maine As A Signal Of Climate Change Impacts, Nicholas Gosling
Phytoplankton Monitoring In Gulf Of Maine As A Signal Of Climate Change Impacts, Nicholas Gosling
UNH Today Archive
No abstract provided.
Philanthropy Under Uncertainty: Muslim Religious Giving During The Covid-19 Pandemic, Osman Umarji, Rafeel Wasif, Shariq Siddiqui, Zeeshan Noor
Philanthropy Under Uncertainty: Muslim Religious Giving During The Covid-19 Pandemic, Osman Umarji, Rafeel Wasif, Shariq Siddiqui, Zeeshan Noor
Public Administration Faculty Publications and Presentations
This study investigates the demographic, religious, and psychological correlates of charitable giving during times of uncertainty. We employ structural equation modeling to understand the mechanisms that underlie faith-based philanthropy amongst Muslims. For this purpose, we analyzed Muslim American philanthropy during the month of Ramadan in 2020, a month traditionally associated with increased religiosity and philanthropy. Utilizing a sample of 1,722 Muslims in the United States and Canada, uncertainty intolerance was associated with financial anxiety (B = .26), which in turn was related to donating less money (B = -.06). Financial anxiety was also associated with subjective financial well-being (B =.-.22), …
Defined-Benefit Pension Plan Funding: Does Managerial Ability Matter?, Surendranath Rakesh Jory, Thanh Ngo, Hongxia Wang
Defined-Benefit Pension Plan Funding: Does Managerial Ability Matter?, Surendranath Rakesh Jory, Thanh Ngo, Hongxia Wang
Finance and Economics
We examine the impact of managerial ability on defined-benefit pension plans in US firms and find that plan funding levels increase with their sponsors' managerial ability. The finding is robust to various model specifications and control for endogeneity. Further analyses show that high-ability managers make higher employer contributions and adopt more conservative and prudent plan assumptions and investment strategies, and that their pension management is value-enhancing. We conclude that more able managers are cognisant of obligations toward pension beneficiaries and fulfil such obligations with better-funded plans, which ultimately benefits shareholders.
This article was published Open Access through the CCU Libraries …
Enhanced Glucose Production In Norepinephrine And Palmitate Stimulated Hepatocytes Following Endurance Training, Ken D. Sumida, Vera M. Lordan, Casey M. Donovan
Enhanced Glucose Production In Norepinephrine And Palmitate Stimulated Hepatocytes Following Endurance Training, Ken D. Sumida, Vera M. Lordan, Casey M. Donovan
Health Sciences and Kinesiology Faculty Articles
Enhanced hepatic gluconeogenesis plays an important role in exercise glucose homeostasis when hepatic glycogen stores are depleted. Livers from trained animals demonstrate greater rates of gluconeogenesis in the presence of elevated substrate with and without hormonal stimulation. Training has been reported to have a particularly profound impact on norepinephrine-stimulated gluconeogenesis, but this was only demonstrated in the presence of other gluconeogenic hormones. Here we reexamine the impact of endurance training on norepinephrine-stimulated gluconeogenesis in the absence of any other hormones. Isolated hepatocytes from trained and untrained rats were incubated in 6 mM lactate with various concentrations of norepinephrine (0 nM–20 …