Digital Commons Network^™

Comparing Multivalent Cross-Linked Sodium Alginate/ Montmorillonite Beads Containing Curcumin Or Cayenne Pepper As Drug Carriers And Their Antimicrobial Resistance, Shionainn Traynor, Shubham Sharma

SURE Journal: Science Undergraduate Research Experience Journal

The aim of the following work was to investigate and compare curcumin and cayenne pepper in microbeads composed of sodium alginate (SA) crosslinked with montmorillonite (MMT) to act as drug carriers and their antimicrobial resistance. The microbeads were prepared through ion-exchange in multivalent solutions of CaCl₂, MgCl₂ and AlCl₃. The microbeads were characterized by Scanning Electron Microscopy (SEM), Energy Dispersive X-ray analysis (EDX) and the time required for intercalation of curcumin and cayenne pepper with MMT. Simulated intestinal fluid (pH 7.3) and gastric fluid (pH 1.2) at 37°C were used for comparison in swelling studies. …

Association Between Body Mass Index, Abdominal Obesity And Menopause-Related Symptoms In Postmenopausal Women, Brianna A. Rice, Patricia Heavey

SURE Journal: Science Undergraduate Research Experience Journal

Abstract: Existing research demonstrates a lack of data on the relationship between body mass index (BMI) and menopause-related symptoms in postmenopausal women, particularly in Ireland. This study aimed to determine whether there is an association between BMI, general abdominal obesity and menopause-related symptoms in postmenopausal women. This should help bridge the data gap regarding postmenopausal women living in Ireland and their symptoms. Introduction: Menopause is defined as the permanent cessation of a woman's menstrual cycle. This is caused by a reduction of the secretion of oestrogen and progesterone, leading to reduced ovarian function. These changes have been attributed …

Reframing The Management Of Irritable Bowel Syndrome: Investigating The Efficacy Of A Modified Low Fodmap Diet Approach On Symptom Response, Tara Howley, Lorraine Cooney, Suzanne L. Doyle

SURE Journal: Science Undergraduate Research Experience Journal

Background/ Objectives: Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction with a multi-faceted pathogenesis. A diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs), known as a low FODMAP diet (LFD), is an effective management option for many, however, it is complex, costly, and restrictive. A milder, modified low FODMAP diet (MLFD) is one suggested alternative, however, data on this approach is lacking. This study aimed to explore the efficacy of a MLFD versus a LFD on symptom improvement in IBS.

Subjects/ Methods: Routine clinical data collected on individuals with a Rome IV IBS diagnosis between August …

Tension Recordings From Primary Bronchi In Acta2-Gcamp8.1-Mvermilion Transgenic Mice, Qais Khalaf, Srijit Ghosh, Keith Thornbury

SURE Journal: Science Undergraduate Research Experience Journal

Contractions in smooth muscle cells are initiated by elevation of cytosolic Ca²⁺. It is of interest to measure Ca²⁺ signals in these cells. Transgenic Acta2-GCaMP8.1-mVermilion (GCaMP) mice express a genetically encoded intracellular fluorescent Ca²⁺ indicator in smooth muscle cells, have been developed to facilitate the study of Ca²⁺. However, there is a concern that the GCaMP Ca²⁺ indicator might buffer Ca²⁺ and interfere with the signals it is designed to measure. Therefore, the aim of this study was to compare tension responses in GCaMP and wild type (WT) mice to determine if …

Review: Cell Mechanisms In The Control Of Inflammatory Foundations Of Obesity And Secondary Metabolic Disorders, Kristin Goldstone, Keelin Irwin, Ava O' Meara-Cushen, Cathy Brougham

SURE Journal: Science Undergraduate Research Experience Journal

Review: Obesity is a global threat to human health that is precipitating epidemically, with almost 2 billion adults categorised as overweight or obese in 2016. Ireland has one of the highest reports of obesity in Europe with 60% of Irish adults reported as overweight or obese. Inflammation plays an integral role in disease pathogenesis and is a major hallmark of obesity and obesity-related secondary co-morbidities. Obesity-related inflammation can precipitate several diseases, such breast cancer, insulin resistance, type II diabetes and cardiovascular issues. As obesity puts human health at inherent risk, the regulation of obesity-related inflammation is therefore a necessary component …

Mathematical Modelling Of Disease Outbreak, Favour Christian, Matthew Molloy

SURE Journal: Science Undergraduate Research Experience Journal

Establishing a model framework for more research necessitates a thorough understanding of the causes, distribution, prevalence, and evolution of infectious illnesses. The main mathematical concept used in this modelling simulation is ordinary differential equations (ODEs). The purpose of this study was to investigate the significance of the many criteria linked to a zombie virus spread. The zombie framework provides an accessible and relatively simple representation of the nature of infectious disease spread, allowing for tractable assumptions and the development of more complex situations.

The models are designed around a zombie outbreak in which the zombie virus is spread through a …

Investigation Into The Effect Of Aspartame On The Expression Of P53 And Bax In Mouse Stomach Tissue, Angelique Cheryl, Aoife Mac Cooey

SURE Journal: Science Undergraduate Research Experience Journal

Introduction: The recent reclassification of aspartame as a Group 2B hazard by the International Agency for Research on Cancer, along with studies suggesting links to cancer, has raised concerns and prompted further investigation. Evidence suggests that aspartame exposure may alter p53 and BAX gene expression, affecting apoptosis in cancer cells. This study aims to examine how aspartame exposure affects p53 and BAX gene expression in normal mouse stomach tissue, shedding light on cellular stress and apoptosis mechanisms.

Methods: Mice were sacrificed, and stomach tissue was excised and divided into control and treatment groups. RNA extraction was carried out in the …

Total Organic Carbon Analysis Of Residual Contaminants In Bioreactor Equipment: A Cleaning Verification Study Using Surface Swabbing, Ciara E. Fitzpatrick, James J. Roche

SURE Journal: Science Undergraduate Research Experience Journal

Contamination is a major issue in the biopharmaceutical industry. Bioreactors must be meticulously cleaned to remove residual impurities and avoid cross-contamination. Cleaning validation is necessary to ensure residual contaminants are reduced to the lowest acceptable limits. Bacterial cells represent the paramount challenge in manufacturing equipment cleaning because they are composed of insoluble organic contaminants. Total organic carbon (TOC) analysis is a fast, highly sensitive, and inexpensive analytical technique commonly used to evaluate the approximate level of organic contamination.

A study was conducted to assess the effectiveness of cleaning procedures in the removal of contaminants from bioreactor equipment by measuring the …

Editorial - Sure Journal Vol 6, Anne M. Friel, Eva Campion, Sinead Loughran

SURE Journal: Science Undergraduate Research Experience Journal

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Emotional Support Animals And University Housing: United States Of America V. University Of Nebraska At Kearney., Elisabeth Goss

MAGIS: Student Development Journal

As mental health issues such as anxiety and depression have become more prevalent on college campuses, requests for emotional support animals have also increased (Hoffman, 2015; Von Bergen, 2015). The case of United States v. University of Nebraska at Kearney has been recognized as establishing the foundational legal guidelines for how institutions should respond. This essay provides an overview of the case, discusses its implications for policy and practice, and examines its impact on students. For the purposes of this paper, emotional support animals are defined as any animal that provides “support, well-being, comfort, aid, or a calming influence through …

Magis Volume 10 Entire Volume, Editors Of Magis

MAGIS: Student Development Journal

No abstract provided.

Does The Frequency And Number Of Eswt Sessions In Patients With Heel Spurs Affect The Final Result Of The Therapy?, Anna Karafová, Daria Budnicka, Barbara Duda-Biernacka, Wioletta Mikuľáková, Marian Karafa

Baltic Journal of Health and Physical Activity

Introduction: In the literature, the effectiveness of the extracorporeal shock wave therapy (ESWT) in patients with heel spur was confirmed, but the therapy protocol has not been established when used as monotherapy. The aim of the study was to verify whether the frequency of ESWT and the number of sessions used as monotherapy in patients with heel spur have an impact on the final result of the therapy. Methods: 85 patients were divided into three subgroups. All patients were treated 5 times with different intervals between ESWT sessions, in the group I, ESWT was administered every day, in group II …

2024 Program, Georgia Southern University

Georgia Association for Positive Behavior Support Conference

No abstract provided.

Proof Of Causation In A Private Action For Acid Rain Damage, Patrick J. Scully

Maine Law Review

The acid rain problem has become one of the major environmental issues of our day. Each new report on the subject is more disturbing than the last, documenting serious and often irreversible effects of acid rain on lakes and streams, fish and other aquatic life, forests, soils, buildings, and even human health. Present federal legislation is inadequate to deal with acid rain effectively. Proposed legislation could help ameliorate the problem, but even if adopted the effects of such proposals will not be felt until early in the next century. Furthermore, the current administration, particularly the Environmental Protection Agency (EPA), has …

The Parent-Child Privilege And The Parent-Child Crime: Observations On State V. Delong And In Re Agosto, Ellen Kandoian

Maine Law Review

Should a child be compelled to testify against his parent under threat of criminal punishment? Ignoring for a moment the applicable legal doctrines, there are several reasons why one might answer no. First, if we value the idea of family loyalty, and believe that loyalty of a child to his parent is particularly important for traditional, moral, and practical reasons, then measures taken by a state to undermine such loyalty must be viewed critically. Second, children tend to accumulate tremendous amounts of information about their parents' activities and are party or witness to many communications made by their parents with …

Analysis Of The Longitudinal Effect Of Home Advantage In The Brazilian Football Championship – Série A, Werlayne Leite, Marcelo C. Zanetti

Baltic Journal of Health and Physical Activity

Athletes and teams typically obtain an advantage when competing at home, a phenomenon known as home advantage (HA). This study investigates the longitudinal effect of HA in the Brazilian Football Championship (Série A) over 21 seasons, analyzing 8,405 matches from 2003 to 2023. The results showed that the average HA was 35.1 ± 7.7%, while the competitive balance (CB) was 0.838 ± 0.145. A negative, non-significant correlation (r = -0.321, p = 0.157) was found between HA and CB, with CB explaining 10.3% of HA variation in the Brazilian league. HA de-creased over time, likely due to improved logistics, …

So You Want To Work With Students, Jeremy Stringer

MAGIS: Student Development Journal

Honoring Jeremy Stringer: Reflections on Caring

The Impact Of Advancement In Higher Education, Thaddeus J. Teo

MAGIS: Student Development Journal

American higher education funding is not just an issue hotly debated by policy makers on Capitol Hill; it is an issue that affects students and their families, and one that student affairs professionals should have on their radars as it continues to make national headlines. From my experience, the impact of a robust institutional advancement program can be often overlooked or misunderstood by educators, including some who work in student affairs. This paper was written with the goal of providing an introductory awareness of the current economic situation as well as a brief understanding of the impact that an effective …

Magis Volume 9 Entire Volume, Editors Of Magis

MAGIS: Student Development Journal

No abstract provided.

Back Matter

The Journal of Purdue Undergraduate Research

No abstract provided.

Interview: Kristine Marceau And Gina Canino-Quiñones, Nikhil S. Sadavarte

The Journal of Purdue Undergraduate Research

Dr. Kristine Marceau is an associate professor in Purdue University’s Department of Human Development and Family Science, and director of the Biobehavioral Development Lab. Her research involves asking questions about the role of biological processes in the development of behavior problems and substance use across people’s lives, with a particular focus on the experiences of children and families. Undergraduate student researcher Gina Canino-Quiñones, who has contributed to this award-supported research, is interviewed along with Marceau.

A Meteorological Investigation Of A Tornado- Producing, “Hybrid” Supercell-Multicell Storm Near Delphi, Indiana, On May 8, 2023, Evelyn Rose K. Girardi

The Journal of Purdue Undergraduate Research

No abstract provided.

Utilizing Wheat Bran–Derived Phenolics To Optimize The Human Gut Microbiome, Youssef Errihani

The Journal of Purdue Undergraduate Research

No abstract provided.

The Influence Of Emotions And Limited Working Memory On Gambling, Haley Crouch

The Journal of Purdue Undergraduate Research

No abstract provided.

Systematic Development And Optimization Of Helix Stabilized Stapled Peptides For Inhibitory Use Against The Viral Oncoprotein Hpv-E6, Elizabeth Andersen

The Journal of Purdue Undergraduate Research

No abstract provided.

Design And Evaluation Of A Novel Binder Protein For Sars-Cov-2 Using The Online Game Foldit, Searre H. Abebe

The Journal of Purdue Undergraduate Research

No abstract provided.

Toxic Waste Dumps And Intersectionality, Kaitlyn Vasilko

The Journal of Purdue Undergraduate Research

No abstract provided.

The Making Of The Black Games Archive (Bga): A Digital Archive Intertwining Black Culture And Play, Joanna Senff

The Journal of Purdue Undergraduate Research

No abstract provided.

Angelman And Fragile X Syndrome Early Sleeping Patterns, Maelyn Fulton

The Journal of Purdue Undergraduate Research

No abstract provided.

Enhancing Bedside Nursing Care: An Artificial Neural Network Approach To Predicting Cardiac Arrest In Hospitalized Adults, Katharine Czech, Alec Pannunzio, Maddie Anderson, Numair Khan, Jacob Lacanienta, Jonghyeok Lee, Aneesh Poddutur, Emily Rastovski, Kira Voelker, Julie Wasyliw, Sei Zou

The Journal of Purdue Undergraduate Research

No abstract provided.