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2024

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Lanthorn, Vol. 58, No. 12, February 12, 2024, Grand Valley State University Feb 2024

Lanthorn, Vol. 58, No. 12, February 12, 2024, Grand Valley State University

Volume 58, August 7, 2023 - April 15, 2024

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present. Issue 12 is misnumbered as "Issue 11."


Faculty Senate Executive Committee Agenda February 20, 2024, Utah State University Feb 2024

Faculty Senate Executive Committee Agenda February 20, 2024, Utah State University

Faculty Senate & Faculty Senate Executive Committee

  • Call to Order
  • Approval of Minutes - January 22, 2024
  • University Business
  • Faculty Senate Business
  • Information
  • Education Policies Committee - December 7, 2023 | January 4, 2024
  • New Limited English Proficiency (LEP) Policy
  • Reports
  • Faculty Diversity, Development, & Equity Annual Report
  • Parking and Transportation Committee Annual Report
  • Sustainability Council Annual Report
  • Old Business
  • Update on IRB Ad Hoc Committee
  • Update on Faculty Code 405
  • New Business

  • Faculty Code 407 Redline - Clean | 408 Redline - Clean
  • Adjourn: 5:00 pm


Well-Being In Response To Gratitude Interventions: A Student Elicitation Approach, Erin A. Hopkins Feb 2024

Well-Being In Response To Gratitude Interventions: A Student Elicitation Approach, Erin A. Hopkins

Journal of Contemplative and Holistic Education

Various methods exist to invoke gratitude, such as gratitude lists, acts directed towards others, and gratitude contemplation (Rash, Matsuba, and Prkachin, 2011). This study, through student perception elicitation, examines a gratitude list intervention in a professional development undergraduate class which tests the gratitude and enhanced well-being connection theory.

Results suggest various reasons why students perceive a connection between gratitude lists and mental and physical well-being, although there was an overall belief among participants that gratitude lists help more with mental health than physical health. Also, the gratitude and enhanced well-being connection theory was not fully supported as overall respondent sentiment …


Applying Generative Artificial Intelligence (Ai) In Health Professions Education, Amy Bachyrycz, Seth Daly, Sharon Schaaf, Kendall Rogers, John Williams Feb 2024

Applying Generative Artificial Intelligence (Ai) In Health Professions Education, Amy Bachyrycz, Seth Daly, Sharon Schaaf, Kendall Rogers, John Williams

HSC Education Days

No abstract provided.


Hsc Connects Newsletter - February 9, 2024, Unm Hsc Communications Feb 2024

Hsc Connects Newsletter - February 9, 2024, Unm Hsc Communications

HSC Connects Newsletters

Weekly newsletter of the UNM Health Sciences Center.


A Pilot Study On Implementing An Interprofessional Education Model For Developing Rehabilitative Science Student Core Competencies, Maureen Ellen Johnson, Norman Cadiz Belleza, Mohan Ganesan Feb 2024

A Pilot Study On Implementing An Interprofessional Education Model For Developing Rehabilitative Science Student Core Competencies, Maureen Ellen Johnson, Norman Cadiz Belleza, Mohan Ganesan

Journal of Innovation in Health Sciences Education

Introduction: Inclusion of interprofessional education (IPE) in academia is required by education accreditation agencies for occupational therapy (OT) and physical therapy (PT) in the United States. Limited information is available on models of IPE to guide faculty. The purpose of this pilot study was to determine the feasibility of implementing a recently designed IPE model with OT and PT graduate students. This IPE model aligned Interprofessional Education Collaborative core competency domains with novel learning activities, such as an escape room, simulated medical chart, and two simulations.

Methods: Data were retrieved from 52 auto-enrolled students (n=14 OT) and (n=38 PT) …


Research, Planning, And Development Of A University Retirement Community (Urc): A Strategic Lodging Opportunity, Tevfik Demirciftci, Britt Mathwich, Fred Demicco Feb 2024

Research, Planning, And Development Of A University Retirement Community (Urc): A Strategic Lodging Opportunity, Tevfik Demirciftci, Britt Mathwich, Fred Demicco

ICHRIE Research Reports

University Retirement Communities (URCs) are a growing trend among universities and senior living. URCs are an intriguing concept that benefits retirees and universities as they bring alums back to campus for their residences. This study investigates the interest level and preferences of Colorado Mesa University's alums and retired professors for an on-campus URC. This research is the first phase of the planning process for developing and operating a successful URC.

Keywords: University-Based Retirement Communities (UBRC), Continuing Care Retirement Communities, Senior Living Communities, Active Adult Communities


Licensed Nurse/Certified Nurse Aide Collaboration In The Nursing Home, Cynthia Beynon Feb 2024

Licensed Nurse/Certified Nurse Aide Collaboration In The Nursing Home, Cynthia Beynon

Dissertations

The purpose of this dissertation was to explore how collaboration is perceived and experienced by the licensed nurse (LN) and the certified nurse aide (CNA) in the nursing home (NH) setting. Understanding perspectives and patterns in the process of LN/CNA collaboration is critical in the quest to secure safe, quality care delivery for NH residents.


A Phenomenological Multi-Case Study Of Perceptions Of Older Adults’ Loneliness During Covid-19 Within Selected Online Churches, Bethney Wright Sikes Feb 2024

A Phenomenological Multi-Case Study Of Perceptions Of Older Adults’ Loneliness During Covid-19 Within Selected Online Churches, Bethney Wright Sikes

Doctoral Dissertations and Projects

The purpose of this phenomenological multi-case study was to understand the perceptions of older adults regarding their feelings of loneliness related to the lockdown during COVID-19 and to discover if online church platforms for the older adult Christian population at Crosspoint Church in Niceville, Florida, Cross Church in Northwest Arkansas, and Community Life Church in Gulf Breeze, Florida, minimized those feelings of loneliness which may have caused mental, physical, and emotional concerns. Isolation from the church body was generally defined as nonattendance via traditional means or online platforms. The theory guiding this study was Lev Vygotsky’s zone of proximal development. …


Like Riding A Bike: Roles Of Wisdom Of A Seasoned Marketing Academic When Developing Scholarly Research, Jack A. Lesser Feb 2024

Like Riding A Bike: Roles Of Wisdom Of A Seasoned Marketing Academic When Developing Scholarly Research, Jack A. Lesser

AMTP Proceedings 2024

The concept of wisdom is concerned with determining what is true, right, and lasting. Individuals learn to make more true, right, and lasting decisions by thinking about wisdom. A seasoned academic in marketing cares about what is true, right, and lasting. This individual generally wishes to develop a legacy around what is true, right, and lasting. Many seasoned academics are resuming their publication careers after having earlier, strong records. Psychologically, how should a seasoned marketing academic manage the later parts of her or his publishing career? What are some general considerations that follow from psychological theories of wisdom about how …


It Takes A Village To Raise A Grandchild: Developing Communities Of Support For Grand-Families On Pei, Canada, Christina Murray, Laura Bain, Nora Spinks, Donald Avery Feb 2024

It Takes A Village To Raise A Grandchild: Developing Communities Of Support For Grand-Families On Pei, Canada, Christina Murray, Laura Bain, Nora Spinks, Donald Avery

GrandFamilies: The Contemporary Journal of Research, Practice and Policy

In this practice brief, we outline our research focused on grandparents raising grandchildren in Prince Edward Island (PEI), Canada. Specifically, we highlight a series of collaborative community workshops implemented as part of our research project. Using a participatory action research approach, we worked with grandparents raising grandchildren to co-design and implement the workshops, which we titled It Takes a Village to Raise a Grandchild. These workshops brought together grandparents raising grandchildren and key community members, including clergy, educators, healthcare providers, politicians, social services, child services, and researchers. The goal of these workshops was to build awareness and increase understanding …


A Global Perspective On Intersecting Social And Systemic Barriers Experienced By Grandparent-Caregivers: A Qualitative Systematic Review, Schola N. Matovu, Deborah M. Whitley, Heather M. Young Feb 2024

A Global Perspective On Intersecting Social And Systemic Barriers Experienced By Grandparent-Caregivers: A Qualitative Systematic Review, Schola N. Matovu, Deborah M. Whitley, Heather M. Young

GrandFamilies: The Contemporary Journal of Research, Practice and Policy

Globally, many grandparents are taking on the caregiving role for their grandchildren without public or government interjection of support, particularly financial assistance for basic needs such as housing, health care and living expenses. This paper aimed to broaden understanding of social and systemic barriers experienced by grandparent-caregivers across the globe. Of the 2,828 relevant grandparent caregiving studies identified in the literature, 34 representing eight countries met our inclusion criteria to answer the research question and the focus of this paper: What are the social and systemic barriers experienced by grandparent-caregivers across the globe? We utilized Noblit’s and Hare’s (1988) meta-ethnography …


Complete Issue Vol. 7, Issue 2 Feb 2024

Complete Issue Vol. 7, Issue 2

GrandFamilies: The Contemporary Journal of Research, Practice and Policy

Complete Issue Vol 7(2)


Faculty Senate Agenda February 5, 2024, Utah State University Feb 2024

Faculty Senate Agenda February 5, 2024, Utah State University

Faculty Senate & Faculty Senate Executive Committee

  • 3:45 Call to Order
  • 3:50 University Business
  • 4:05 Faculty Senate Business
  • 4:10 Information
  • 4:25 Reports
  • 4:45 Old Business
  • 4:50 New Business
  • Adjourn: 5:00 pm


Nurse Practitioners In Critical Care Transport, David M. Kaniecki, Robert L. Grabowski, David Holloway Feb 2024

Nurse Practitioners In Critical Care Transport, David M. Kaniecki, Robert L. Grabowski, David Holloway

Faculty Scholarship

The inclusion of nurse practitioners (NPs) in critical care transport teams has the potential to enhance patient care and improve team operations. NPs can manage complex clinical situations during transport and excel in various roles such as leadership, education, mentoring, research, quality improvement, and clinical expertise. As we navigate the evolving landscape of critical care transport, it is crucial to explore the potential benefits offered by NPs. Their distinct skills and experiences effectively position them to improve patient outcomes, enhance team performance, and contribute to health care's financial sustainability. This article discusses the role of NPs in critical care transport, …


Reducing Loneliness And Improving Social Support Among Older Adults Through Different Modalities Of Personal Voice Assistants, Valerie Jones, Changmin Yan, Marcia Shade, Julie Blaskewicz Boron, Zhengxu Yan, Hyeon Jung Heselton, Kate Johnson, Victoria Dube Feb 2024

Reducing Loneliness And Improving Social Support Among Older Adults Through Different Modalities Of Personal Voice Assistants, Valerie Jones, Changmin Yan, Marcia Shade, Julie Blaskewicz Boron, Zhengxu Yan, Hyeon Jung Heselton, Kate Johnson, Victoria Dube

College of Journalism and Mass Communications: Faculty Publications

This study examines the potential of AI-powered personal voice assistants (PVAs) in reducing loneliness and increasing social support among older adults. With the aging population rapidly expanding, innovative solutions are essential. Prior research has indicated the effectiveness of various interactive communication technologies (ICTs) in mitigating loneliness, but studies focusing on PVAs, particularly considering their modality (audio vs. video), are limited. This research aims to fill this gap by evaluating how voice assistants, in both audio and video formats, influence perceived loneliness and social support. This study examined the impact of voice assistant technology (VAT) interventions, both audio-based (A-VAT) and video-based …


Visual Methods For Qualitative Research With Older Refugees: Reflection On Strengths And Drawbacks, Prince Chiagozie Ekoh, Christine A. Walsh Feb 2024

Visual Methods For Qualitative Research With Older Refugees: Reflection On Strengths And Drawbacks, Prince Chiagozie Ekoh, Christine A. Walsh

The Qualitative Report

Although older refugees have similar characteristics and vulnerabilities as other populations that have benefited from visual research methods, there is scarce evidence of these methods being used for qualitative social work studies with older refugees. In this article, we discuss the application of visual methods for social work research with older refugees for a better understanding of their experiences and challenges, highlighting how it can be evocative, improve discussions by reaching senses that ordinary interviews cannot grasp, avoid re-traumatisation during research, and build resilience and coping in older refugees. We propose that visual methods could address power dynamics that privilege …


Development Of Interprofessional Socialization In A Multifaceted Live Action Clinical Role-Play Simulation For Speech-Language Pathology And Social Work Students, Cody Marie Busch, Jennifer Anderson, Lynn Gilbertson, Sarah Hessenauer Feb 2024

Development Of Interprofessional Socialization In A Multifaceted Live Action Clinical Role-Play Simulation For Speech-Language Pathology And Social Work Students, Cody Marie Busch, Jennifer Anderson, Lynn Gilbertson, Sarah Hessenauer

Teaching and Learning in Communication Sciences & Disorders

Live action clinical role-plays are one of many types of simulated learning experiences that can be crafted for undergraduate and graduate students alike when learning to collaborate interprofessionally. This mixed methods exploratory research project partnered four academic instructors from the disciplines of speech-language pathology and social work, with several additional community members adding their expertise to enrich the experience of a live-action clinical role-play. Students (N = 32) participated in a two-part multifaceted interprofessional education (IPE) experience with the first part consisting of eight hours of online asynchronous training and the second part consisting of eight hours of a multifaceted …


Social Engagement, Social Networks, And Well-Being Of Older Adults By Gender And Marital Status, Rachel Wen Yi Ngu, Yi Wen Tan, Yan Er Tan, Wei Tin Hiah Feb 2024

Social Engagement, Social Networks, And Well-Being Of Older Adults By Gender And Marital Status, Rachel Wen Yi Ngu, Yi Wen Tan, Yan Er Tan, Wei Tin Hiah

ROSA Research Briefs

In this research brief, we explore the differences in well-being, social engagement, and social networks amongst groups of married and unmarried male and female older adults and discuss potential policy implications. Our study found that single older adult men fared significantly worse than their married counterparts and single older adult women across different aspects of social well-being, such as social engagement and social support. While this emphasizes the need for increased community efforts to engage men, especially single men, in social activities, specific outreach efforts may be required to better understand their needs and how community programmes can address them.


Assessment Of Salivary Cadmium Levels And Breast Density In The Marin Women's Study, Michaela F. George, Shayne Paff, Jenyse Rojo, Mark Powell, Christopher Benz, Karl Pope, Karla Kerlikowske, John Shepard, Matthew Willis, Rochelle Ereman, Leeann Prebil Feb 2024

Assessment Of Salivary Cadmium Levels And Breast Density In The Marin Women's Study, Michaela F. George, Shayne Paff, Jenyse Rojo, Mark Powell, Christopher Benz, Karl Pope, Karla Kerlikowske, John Shepard, Matthew Willis, Rochelle Ereman, Leeann Prebil

Global Public Health | Faculty Scholarship

Background: We aimed to determine if salivary cadmium (Cd) levels had any association with breast density, hoping to establish a less invasive cost-effective method of stratifying Cd burden as an environmental breast cancer risk factor.

Methods: Salivary Cd levels were quantified from the Marin Women's Study, a Marin County, California population composite. Volumetric compositional breast density (BDsxa) data were measured by single x-ray absorptiometry techniques. Digital screening mammography was performed by the San Francisco Mammography Registry. Radiologists reviewed mammograms and assigned a Breast Imaging-Reporting and Data System score. Early morning salivary Cd samples were assayed. Association analyses were then …


Calorie Restriction Reduces Biomarkers Of Cellular Senescence In Humans, Zaira Aversa, Thomas A. White, Amanda A. Heeren, Cassondra A. Hulshizer, Dominik Saul, Xu Zhang, Anthony J.A. Molina, Leanne M. Redman, Corby K. Martin, Susan B. Racette, Kim M. Huffman, Manjushri Bhapkar, Sundeep Khosla, Sai Krupa Das, Roger A. Fielding, Elizabeth J. Atkinson, Nathan K. Lebrasseur Feb 2024

Calorie Restriction Reduces Biomarkers Of Cellular Senescence In Humans, Zaira Aversa, Thomas A. White, Amanda A. Heeren, Cassondra A. Hulshizer, Dominik Saul, Xu Zhang, Anthony J.A. Molina, Leanne M. Redman, Corby K. Martin, Susan B. Racette, Kim M. Huffman, Manjushri Bhapkar, Sundeep Khosla, Sai Krupa Das, Roger A. Fielding, Elizabeth J. Atkinson, Nathan K. Lebrasseur

Clinical Research Faculty Publications

Calorie restriction (CR) with adequate nutrient intake is a potential geroprotective intervention. To advance this concept in humans, we tested the hypothesis that moderate CR in healthy young-to-middle-aged individuals would reduce circulating biomarkers of cellular senescence, a fundamental mechanism of aging and aging-related conditions. Using plasma specimens from the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE™) phase 2 study, we found that CR significantly reduced the concentrations of several senescence biomarkers at 12 and 24 months compared to an ad libitum diet. Using machine learning, changes in biomarker concentrations emerged as important predictors of the change …


Prevalence And Factors Associated With Frailty Among Older Adults Living With Hiv Compared To Their Uninfected Peers From The Kenyan Coast, Patrick Nzivo Mwangala, Carophine Nasambu, Ryan G. Wagner, Charles R. Newton, Amina Abubakar Feb 2024

Prevalence And Factors Associated With Frailty Among Older Adults Living With Hiv Compared To Their Uninfected Peers From The Kenyan Coast, Patrick Nzivo Mwangala, Carophine Nasambu, Ryan G. Wagner, Charles R. Newton, Amina Abubakar

Institute for Human Development, East Africa

Objectives: a) To document the prevalence and correlates of frailty among older adults living with HIV (OALWH) and their uninfected peers, and b) Investigate HIV status as an independent predictor of frailty.

Methods: This cross-sectional study was conducted between 2020 and 2021 at the Kenyan coast among 440 older adults aged ≥50 years (257 OALWH). Frailty was assessed using the Reported Edmonton Frail Scale. Logistic regression was used to examine the correlates of frailty.

Results: The prevalence of frailty was significantly higher among OALWH (24%) than their uninfected peers (13%). HIV seropositivity was not independently associated with frailty. Sleeping difficulties, …


Faculty Senate Chronicle February 1, 2024, Heather Loughney Feb 2024

Faculty Senate Chronicle February 1, 2024, Heather Loughney

The University of Akron Faculty Senate Chronicle

Minutes for the regular meeting of The University of Akron Faculty Senate on February 1, 2024


Comparing Survival Rates And Mortality In Operative Versus Nonoperative Treatment For Femoral Neck Fractures Among Alzheimer's Disease Patients: A Retrospective Cohort Study, Yijiong Yang, Stacy A Drake, Jing Wang, Gordon C Shen, Hongyu Miao, Robert O Morgan, Xianglin L Du, David R Lairson Feb 2024

Comparing Survival Rates And Mortality In Operative Versus Nonoperative Treatment For Femoral Neck Fractures Among Alzheimer's Disease Patients: A Retrospective Cohort Study, Yijiong Yang, Stacy A Drake, Jing Wang, Gordon C Shen, Hongyu Miao, Robert O Morgan, Xianglin L Du, David R Lairson

Faculty, Staff and Student Publications

INTRODUCTION: Addressing femoral neck fractures resulting from ground-level falls in older adults with Alzheimer's disease (AD) involves a personalized treatment plan. There is considerable ongoing debate concerning the relative advantages and disadvantages of surgical treatment (internal fixation or arthroplasty) vs nonoperative treatment for femoral neck fractures in older persons with AD.

METHODS: This retrospective cohort study compared the mortality, hazard ratio, and survival rate between operative and nonoperative treatments, controlling for patients' demographic information and baseline health status. The study population consisted of Optum beneficiaries diagnosed with AD who experienced an initial femoral neck fracture claim between January 1, 2012, …


The Primary Care Np's Guide To Prevention And Management Of Falls In Older Adults, Janice Mark Feb 2024

The Primary Care Np's Guide To Prevention And Management Of Falls In Older Adults, Janice Mark

Nursing and Health Professions Faculty Research and Publications

Falls are a growing health concern affecting older adults (defined as ages 65 years and older) that can lead to devastating consequences. NPs in primary care settings play an important role in the prevention and management of older adult falls. Methods and resources to screen for fall risk, assess risk factors, and manage falls in older adults are discussed.


Enhancing Sell-Type Home Reversion Products For Retirement Financing, Koon Shing Kwong, Jing Rong Goh, Ting Lin Collin Chua Feb 2024

Enhancing Sell-Type Home Reversion Products For Retirement Financing, Koon Shing Kwong, Jing Rong Goh, Ting Lin Collin Chua

Research Collection School Of Economics

Loan-type reverse mortgage plans and sell-type home reversion plans for retirement financing are two well-known equity release plans that entitle homeowners not only to release cash from their properties but also to allow them to age in place. Recently, a new hybrid equity release plan was proposed to incorporate the home reversion plan’s features with an option of staying in the property for a fixed period without being subject to survival. This additional option provides flexibility to homeowners to better meet their retirement financial and personal needs by reducing the financial uncertainty of home reversion products. In this article, we …


Psyx 536.01: Advanced Child And Adolescent Psychopathology, Gregory R. Machek Feb 2024

Psyx 536.01: Advanced Child And Adolescent Psychopathology, Gregory R. Machek

University of Montana Course Syllabi, 2021-2025

No abstract provided.


Risk Factors For Post-Discharge Adverse Outcomes Following Hospitalization Among Older Adults Diagnosed With Elder Mistreatment, Monique R Pappadis, Leila Wood, Allen Haas, Jordan Westra, Yong-Fang Kuo, Charles P Mouton Feb 2024

Risk Factors For Post-Discharge Adverse Outcomes Following Hospitalization Among Older Adults Diagnosed With Elder Mistreatment, Monique R Pappadis, Leila Wood, Allen Haas, Jordan Westra, Yong-Fang Kuo, Charles P Mouton

Faculty, Staff and Student Publications

Using 100% Medicare data files, this study explored whether primary elder mistreatment (EM) diagnosis, EM type, and facility type were associated with 3-year mortality and 1-year unplanned hospital readmission among older patients diagnosed with EM with hospital discharge from 10/01/2015 through 12/31/2018 (n = 11,023). We also examined outcome differences between older patients diagnosed with EM and matched non-EM patient controls. Neglect by others was the most common EM diagnosis. Three-year mortality was 56.7% and one-year readmission rate was 53.8%. Compared to matched non-EM patient controls, older EM patients were at an increased risk of mortality and readmission. Among …


Intracranial Volume Is Driven By Both Genetics And Early Life Exposures: The Sol-Inca-Mri Study, Tamar Sofer, Einat Granot-Hershkovitz, Wassim Tarraf, Paola Filigrana, Carmen R Isasi, Shakira F Suglia, Robert Kaplan, Kent Taylor, Martha L Daviglus, Fernando D Testai, Donglin Zeng, Jianwen Cai, Myriam Fornage, Hector M González, Charles Decarli Feb 2024

Intracranial Volume Is Driven By Both Genetics And Early Life Exposures: The Sol-Inca-Mri Study, Tamar Sofer, Einat Granot-Hershkovitz, Wassim Tarraf, Paola Filigrana, Carmen R Isasi, Shakira F Suglia, Robert Kaplan, Kent Taylor, Martha L Daviglus, Fernando D Testai, Donglin Zeng, Jianwen Cai, Myriam Fornage, Hector M González, Charles Decarli

Faculty, Staff and Student Publications

Intracranial volume (ICV) reflects maximal brain development and is associated with later-life cognitive abilities. We quantified ICV among first- and second-generation Hispanic and Latino adults from the Study of Latinos-Investigation of Cognitive Aging - MRI (SOL-INCA-MRI), estimated ICV heritability, and tested its associations with previously reported genetic variants, both individually and as a genetic risk score (GRS). We also estimated the association of ICV with early life environmental measures: nativity or age of immigration and parental education. The estimated heritability of ICV was 19% (95% CI, 0.1%-56%) in n=1781 unrelated SOL-INCA-MRI individuals. Four of 10 tested genetic variants were associated …


Biological Aging Markers In Blood And Brain Tissue Indicate Age Acceleration In Alcohol Use Disorder, Lea Zillich, Metin Cetin, Elisabeth M Hummel, Eric Poisel, Gabriel R Fries, Josef Frank, Fabian Streit, Jerome C Foo, Lea Sirignano, Marion M Friske, Bernd Lenz, Sabine Hoffmann, Kristina Adorjan, Falk Kiefer, Georgy Bakalkin, Anita C Hansson, Falk W Lohoff, Olli Kärkkäinen, Eloise Kok, Pekka J Karhunen, Greg T Sutherland, Consuelo Walss-Bass, Rainer Spanagel, Marcella Rietschel, Dirk A Moser, Stephanie H Witt Feb 2024

Biological Aging Markers In Blood And Brain Tissue Indicate Age Acceleration In Alcohol Use Disorder, Lea Zillich, Metin Cetin, Elisabeth M Hummel, Eric Poisel, Gabriel R Fries, Josef Frank, Fabian Streit, Jerome C Foo, Lea Sirignano, Marion M Friske, Bernd Lenz, Sabine Hoffmann, Kristina Adorjan, Falk Kiefer, Georgy Bakalkin, Anita C Hansson, Falk W Lohoff, Olli Kärkkäinen, Eloise Kok, Pekka J Karhunen, Greg T Sutherland, Consuelo Walss-Bass, Rainer Spanagel, Marcella Rietschel, Dirk A Moser, Stephanie H Witt

Faculty, Staff and Student Publications

Background: Alcohol use disorder (AUD) is associated with increased mortality and morbidity risk. A reason for this could be accelerated biological aging, which is strongly influenced by disease processes such as inflammation. As recent studies of AUD show changes in DNA methylation and gene expression in neuroinflammation-related pathways in the brain, biological aging represents a potentially important construct for understanding the adverse effects of substance use disorders. Epigenetic clocks have shown accelerated aging in blood samples from individuals with AUD. However, no systematic evaluation of biological age measures in AUD across different tissues and brain regions has been undertaken.

Methods: …