Digital Commons Network^™

Applying Market Basket Analysis To Determine Complex Coassociations Among Food Allergens In Children With Food Protein-Induced Enterocolitis Syndrome (Fpies), Ankona Banerjee, Kenneth Nobleza, Cynthia Haddad, Joshua Eubanks, Ruchit Rana, Nicholas L Rider, Lisa Pompeii, Duc Nguyen, Sara Anvari

Faculty, Staff and Students Publications

BACKGROUND: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy, characterized by delayed onset of repetitive vomiting occurring 1 to 4 h following ingestion of a food allergen. Managing FPIES requires strict avoidance of the food trigger. The concern with FPIES is determining the risk of another FPIES food trigger reaction due to potential coassociations with other foods or food groups. An effective statistical approach for analyzing FPIES-related data is essential to identify common coallergens and their associations.

METHODS: This study employed Market Basket Analysis, a data-mining technique, to examine correlations and patterns among allergens in FPIES patients at …

Levofloxacin Prophylaxis For Pediatric Leukemia Patients: Monitoring Of Outcomes For Sustained Benefit And Consequences, Andrea L Davis, Alexandra M Stevens, Julienne Brackett, Lucila Marquez, Catherine E Foster, Adriana Sarmiento Clemente, Hannah E Sauer, Grant T Stimes, Judith R Campbell

Faculty, Staff and Students Publications

Levofloxacin prophylaxis reduces bloodstream infections in neutropenic patients with acute myeloid leukemia or relapsed acute lymphoblastic leukemia. A retrospective, longitudinal cohort study compares incidence of bacteremia, multidrug-resistant organisms (MDRO), and Clostridioides difficile (CDI) between time periods of levofloxacin prophylaxis implementation. Benefits were sustained without increasing MDRO or CDI.

Efficacy And Safety Of Lumasiran For Infants And Young Children With Primary Hyperoxaluria Type 1: 30-Month Analysis Of The Phase 3 Illuminate-B Trial, Yaacov Frishberg, Wesley Hayes, Hadas Shasha-Lavsky, David J Sas, Mini Michael, Anne-Laure Sellier-Leclerc, Julien Hogan, Richard Willey, John M Gansner, Daniella Magen

Faculty, Staff and Students Publications

BACKGROUND: Primary hyperoxaluria type 1 (PH1) is a genetic disorder resulting in overproduction of hepatic oxalate, potentially leading to recurrent kidney stones, nephrocalcinosis, chronic kidney disease, and kidney failure. Lumasiran, the first RNA interference therapeutic approved for infants and young children, is a liver-directed treatment that reduces hepatic oxalate production. Lumasiran demonstrated sustained efficacy with an acceptable safety profile over 12 months in infants and young children (age <6 >years) with PH1 in ILLUMINATE-B (clinicaltrials.gov: NCT03905694), an ongoing, Phase 3, multinational, open-label, single-arm study.

METHODS: Here, we report interim efficacy and safety findings from ILLUMINATE-B following 30 months of lumasiran treatment. …

Population-Based Screening Strategies For Biliary Atresia In The Newborn: A Systematic Review And Meta-Analysis, Srirupa Hari Gopal, Rema Zebda, Arvind Mohan, Kristin Borovsky, Yemisi Takwoingi, Katie Scandrett, Mohan Pammi

Faculty, Staff and Students Publications

BACKGROUND: Newborn screening for biliary atresia (BA) may facilitate earlier diagnosis and intervention for improved clinical outcomes.

METHODS: We systematically reviewed the accuracy of population-based screening strategies for BA in the newborn using PRISMA-DTA guidelines. We included cohort or cross-sectional studies. The screening (index) tests included stool color card (SCC) and direct/conjugated bilirubin (DB/CB) and the reference standard was intraoperative cholangiogram. Meta-analysis was performed using random-effects logistic regression models.

RESULTS: We included 15 studies (1,816,722 participants) that assessed 5 different population-based screening strategies. QUADAS-2 assessment revealed high risk of bias for patient selection in one study and uncertain risks for …

Researching Covid To Enhance Recovery (Recover) Pediatric Study Protocol: Rationale, Objectives And Design, Rachel S Gross, Tanayott Thaweethai, Erika B Rosenzweig, James Chan, Lori B Chibnik, Mine S Cicek, Amy J Elliott, Valerie J Flaherman, Andrea S Foulkes, Margot Gage Witvliet, Richard Gallagher, Maria Laura Gennaro, Terry L Jernigan, Elizabeth W Karlson, Stuart D Katz, Patricia A Kinser, Lawrence C Kleinman, Michelle F Lamendola-Essel, Joshua D Milner, Sindhu Mohandas, Praveen C Mudumbi, Jane W Newburger, Kyung E Rhee, Amy L Salisbury, Jessica N Snowden, Cheryl R Stein, Melissa S Stockwell, Kelan G Tantisira, Moriah E Thomason, Dongngan T Truong, David Warburton, John C Wood, Shifa Ahmed, Almary Akerlundh, Akram N Alshawabkeh, Brett R Anderson, Judy L Aschner, Andrew M Atz, Robin L Aupperle, Fiona C Baker, Venkataraman Balaraman, Dithi Banerjee, Deanna M Barch, Arielle Baskin-Sommers, Sultana Bhuiyan, Marie-Abele C Bind, Amanda L Bogie, Tamara Bradford, Natalie C Buchbinder, Elliott Bueler, Hülya Bükülmez, B J Casey, Linda Chang, Maryanne Chrisant, Duncan B Clark, Rebecca G Clifton, Katharine N Clouser, Lesley Cottrell, Kelly Cowan, Viren D'Sa, Mirella Dapretto, Soham Dasgupta, Walter Dehority, Audrey Dionne, Kirsten B Dummer, Matthew D Elias, Shari Esquenazi-Karonika, Danielle N Evans, E Vincent S Faustino, Alexander G Fiks, Daniel Forsha, John J Foxe, Naomi P Friedman, Greta Fry, Sunanda Gaur, Dylan G Gee, Kevin M Gray, Stephanie Handler, Ashraf S Harahsheh, Keren Hasbani, Andrew C Heath, Camden Hebson, Mary M Heitzeg, Christina M Hester, Sophia Hill, Laura Hobart-Porter, Travis K F Hong, Carol R Horowitz, Daniel S Hsia, Matthew Huentelman, Kathy D Hummel, Katherine Irby, Joanna Jacobus, Vanessa L Jacoby, Pei-Ni Jone, David C Kaelber, Tyler J Kasmarcak, Matthew J Kluko, Jessica S Kosut, Angela R Laird, Jeremy Landeo-Gutierrez, Sean M Lang, Christine L Larson, Peter Paul C Lim, Krista M Lisdahl, Brian W Mccrindle, Russell J Mcculloh, Kimberly Mchugh, Alan L Mendelsohn, Torri D Metz, Julie Miller, Elizabeth C Mitchell, Lerraughn M Morgan, Eva M Müller-Oehring, Erica R Nahin, Michael C Neale, Manette Ness-Cochinwala, Sheila M Nolan, Carlos R Oliveira, Onyekachukwu Osakwe, Matthew E Oster, R Mark Payne, Michael A Portman, Hengameh Raissy, Isabelle G Randall, Suchitra Rao, Harrison T Reeder, Johana M Rosas, Mark W Russell, Arash A Sabati, Yamuna Sanil, Alice I Sato, Michael S Schechter, Rangaraj Selvarangan, S Kristen Sexson Tejtel, Divya Shakti, Kavita Sharma, Lindsay M Squeglia, Shubika Srivastava, Michelle D Stevenson, Jacqueline Szmuszkovicz, Maria M Talavera-Barber, Ronald J Teufel, Deepika Thacker, Felicia Trachtenberg, Mmekom M Udosen, Megan R Warner, Sara E Watson, Alan Werzberger, Jordan C Weyer, Marion J Wood, H Shonna Yin, William T Zempsky, Emily Zimmerman, Benard P Dreyer, Recover-Pediatric Consortium

Faculty, Staff and Students Publications

IMPORTANCE: The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long COVID") in children and young adults remain unknown. Studies must address the urgent need to define PASC, its mechanisms, and potential treatment targets in children and young adults.

OBSERVATIONS: We describe the protocol for the Pediatric Observational Cohort Study of the NIH's REsearching COVID to Enhance Recovery (RECOVER) Initiative. RECOVER-Pediatrics is an observational meta-cohort study of caregiver-child pairs (birth through 17 years) and young adults (18 through 25 years), recruited from more than 100 sites across the US. This report focuses on two of …

Functional Genomics And Small Molecules In Mitochondrial Neurodevelopmental Disorders, Daniel G Calame, Lisa T Emrick

Faculty, Staff and Students Publications

Mitochondria are critical for brain development and homeostasis. Therefore, pathogenic variation in the mitochondrial or nuclear genome which disrupts mitochondrial function frequently results in developmental disorders and neurodegeneration at the organismal level. Large-scale application of genome-wide technologies to individuals with mitochondrial diseases has dramatically accelerated identification of mitochondrial disease-gene associations in humans. Multi-omic and high-throughput studies involving transcriptomics, proteomics, metabolomics, and saturation genome editing are providing deeper insights into the functional consequence of mitochondrial genomic variation. Integration of deep phenotypic and genomic data through allelic series continues to uncover novel mitochondrial functions and permit mitochondrial gene function dissection on an …

Metabolic Bioactivation Of Antidepressants: Advance And Underlying Hepatotoxicity, Saleh M Khalil, Kevin R Mackenzie, Mirjana Maletic-Savatic, Feng Li

Faculty, Staff and Students Publications

Many drugs that serve as first-line medications for the treatment of depression are associated with severe side effects, including liver injury. Of the 34 antidepressants discussed in this review, four have been withdrawn from the market due to severe hepatotoxicity, and others carry boxed warnings for idiosyncratic liver toxicity. The clinical and economic implications of antidepressant-induced liver injury are substantial, but the underlying mechanisms remain elusive. Drug-induced liver injury may involve the host immune system, the parent drug, or its metabolites, and reactive drug metabolites are one of the most commonly referenced risk factors. Although the precise mechanism by which …

Mecp2-Related Disorders While Gene-Based Therapies Are On The Horizon, Katherine Allison, Mirjana Maletic-Savatic, Davut Pehlivan

Faculty, Staff and Students Publications

The emergence of new genetic tools has led to the discovery of the genetic bases of many intellectual and developmental disabilities. This creates exciting opportunities for research and treatment development, and a few genetic disorders (e.g., spinal muscular atrophy) have recently been treated with gene-based therapies. MECP2 is found on the X chromosome and regulates the transcription of thousands of genes. Loss of MECP2 gene product leads to Rett Syndrome, a disease found primarily in females, and is characterized by developmental regression, motor dysfunction, midline hand stereotypies, autonomic nervous system dysfunction, epilepsy, scoliosis, and autistic-like behavior. Duplication of MECP2 causes …

Etiology Of Hospital Mortality In Children Living In Low- And Middle-Income Countries: A Systematic Review And Meta-Analysis, Teresa B Kortz, Rishi P Mediratta, Audrey M Smith, Katie R Nielsen, Asya Agulnik, Stephanie Gordon Rivera, Hailey Reeves, Nicole F O'Brien, Jan Hau Lee, Qalab Abbas, Jonah E Attebery, Tigist Bacha, Emaan G Bhutta, Carter J Biewen, Jhon Camacho-Cruz, Alvaro Coronado Muñoz, Mary L Dealmeida, Larko Domeryo Owusu, Yudy Fonseca, Shubhada Hooli, Hunter Wynkoop, Mara Leimanis-Laurens, Deogratius Nicholaus Mally, Amanda M Mccarthy, Andrew Mutekanga, Carol Pineda, Kenneth E Remy, Sara C Sanders, Erica Tabor, Adriana Teixeira Rodrigues, Justin Qi Yuee Wang, Niranjan Kissoon, Yemisi Takwoingi, Matthew O Wiens, Adnan Bhutta

Faculty, Staff and Students Publications

In 2019, 80% of the 7.4 million global child deaths occurred in low- and middle-income countries (LMICs). Global and regional estimates of cause of hospital death and admission in LMIC children are needed to guide global and local priority setting and resource allocation but are currently lacking. The study objective was to estimate global and regional prevalence for common causes of pediatric hospital mortality and admission in LMICs. We performed a systematic review and meta-analysis to identify LMIC observational studies published January 1, 2005-February 26, 2021. Eligible studies included: a general pediatric admission population, a cause of admission or death, …

Protein Biomarkers Gdf15 And Fgf21 To Differentiate Mitochondrial Hepatopathies From Other Pediatric Liver Diseases, Johan L K Van Hove, Marisa W Friederich, Dana K Strode, Roxanne A Van Hove, Kristen R Miller, Rohit Sharma, Hardik Shah, Jane Estrella, Linda Gabel, Simon Horslen, Rohit Kohli, Mark A Lovell, Alexander G Miethke, Jean P Molleston, Rene Romero, James E Squires, Estella M Alonso, Stephen L Guthery, Binita M Kamath, Kathleen M Loomes, Philip Rosenthal, Krupa R Mysore, Laurel A Cavallo, Pamela L Valentino, John C Magee, Shikha S Sundaram, Ronald J Sokol, Childhood Liver Disease Research Network (Children)

Faculty, Staff and Students Publications

BACKGROUND: Mitochondrial hepatopathies (MHs) are primary mitochondrial genetic disorders that can present as childhood liver disease. No recognized biomarkers discriminate MH from other childhood liver diseases. The protein biomarkers growth differentiation factor 15 (GDF15) and fibroblast growth factor 21 (FGF21) differentiate mitochondrial myopathies from other myopathies. We evaluated these biomarkers to determine if they discriminate MH from other liver diseases in children.

METHODS: Serum biomarkers were measured in 36 children with MH (17 had a genetic diagnosis); 38 each with biliary atresia, α1-antitrypsin deficiency, and Alagille syndrome; 20 with NASH; and 186 controls.

RESULTS: GDF15 levels compared to controls were …

Smooth Muscle Contractile Responses To Bile Acids In Mouse Ileum Require Tgr5 But Not Asbt, Diana S Chang, Krishnakant G Soni, Geoffrey A Preidis

Faculty, Staff and Students Publications

BACKGROUND: Many disorders of gut-brain interaction (DGBIs) are more prevalent in women than men and feature alterations in gastrointestinal motility and bile acid homeostasis. Mechanisms by which bile acids regulate gastrointestinal motility are poorly characterized. We recently validated an adapted tissue bath technique using everted mouse ileum, which revealed differential contractile responses to ursodeoxycholic acid (UDCA) and deoxycholic acid (DCA). Here, we aimed to determine whether these responses are dependent on host sex, the plasma membrane bile acid receptor TGR5, or the apical sodium-dependent bile acid transporter ASBT.

METHODS: Ileal segments from male and female mice were everted and suspended …

Special Session: Writing For The Ieee Teaching Excellence Hub, Steve Eugene Watkins

Electrical and Computer Engineering Faculty Research & Creative Works

Technical educators can benefit by sharing practices, techniques, experiences, and approaches that have been successful in their classrooms. The IEEE Teaching Excellence Hub (TEH) provides curated educational materials and resources for those teaching engineering, computing, and technology at the university level. This virtual venue for professional development is intended to complement resources found through educational journals and conferences. The online site contains practice-oriented articles, event links, and other collections that are contributed by the engineering education community. This special session will provide an overview of the TEH platform and will prepare attendees for contributing as reviewers and authors. The target …

Optimal Tilt-Wing Evtol Takeoff Trajectory Prediction Using Regression Generative Adversarial Networks, Shuan Tai Yeh, Xiaosong Du

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Electric vertical takeoff and landing (eVTOL) aircraft have attracted tremendous attention nowadays due to their flexible maneuverability, precise control, cost efficiency, and low noise. The optimal takeoff trajectory design is a key component of cost-effective and passenger-friendly eVTOL systems. However, conventional design optimization is typically computationally prohibitive due to the adoption of high-fidelity simulation models in an iterative manner. Machine learning (ML) allows rapid decision making; however, new ML surrogate modeling architectures and strategies are still desired to address large-scale problems. Therefore, we showcase a novel regression generative adversarial network (regGAN) surrogate for fast interactive optimal takeoff trajectory predictions of …

Effect Of Bioactive Borate Glass On Printability And Physical Properties Of Hydrogels, Fateme Fayyazbakhsh, Mehedi H. Tusar, Yue-Wern Huang, Ming C. Leu

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Hydrogels are a key component in bioinks and biomaterial inks for bioprinting due to their biocompatibility and printability at room temperature. The research described in the present paper contributes to the advancement of bioprinting by studying the effect of bioactive borate glass (BBG) incorporated into hydrogels on printability and physical properties. In this study, we fabricated 3D-printed hydrogel scaffolds using gelatin and alginate hydrogel mixture incorporated with various amounts of BBG, a bio ceramic rich in therapeutic ions including boron, calcium, copper, and zinc. We investigated the effect of incorporating BBG on the density, viscosity, physical interactions, chemical structure, and …

Impact Of Aging On Pim And Dc Resistance Of Fabric-Over-Foam Metallic Contacts, Kalkidan W. Anjajo, Seunghun Ryu, Shengxuan Xia, Gracie Boyer, Yuchu He, Haicheng Zhou, Hanfeng Wang, Jonghyun Park, Chulsoon Hwang

Mechanical and Aerospace Engineering Faculty Research & Creative Works

In this paper the impact of aging on the level of passive intermodulation (PIM) and DC resistance of fabric-over-foam metallic contacts is presented. These contacts are widely used to maintain metallic connections between modules and chassis in electronic devices. The PIM caused by the loose metallic contact of these materials mainly affects a receiver's RF sensitivity in mobile devices. This aging test under elevated temperature and relative humidity conditions offers an experiment-based approach with respect to various metallic contact cases. Energy dispersive spectroscopy and scanning electron microscopy are used to characterize the change in material composition and the contact surface …

Phenolic Polymer Infiltration And Pyrolysis Process For Additively Manufactured Carbon/Peek Composites To Produce Carbon–Carbon Composites, S. Weiler, H. A. Haffner, K. Chandrashekhara, J. Watts, G. E. Hilmas, J. Bayldon, L. M. Rueschhoff

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Carbon–carbon composites are carbon fibers reinforced with carbon matrix and are classified as advanced materials well suited for high-temperature structural applications. Carbon–carbon composites are characterized by maintaining excellent mechanical properties and structural stability at high temperatures and have been used in aerospace application as nozzles, heatshields, and leading edge. However, conventional methods to manufacture carbon–carbon composites are costly and time-consuming. the aim of this work is to develop a method for creating additively manufactured (AM) carbon–carbon composites using a high-pressure re-infiltration process. in doing so, less infiltration cycles are required compared to a low-pressure re-infiltration, reducing the total manufacture time. …

Cascaded Weak Reflector Coaxial Cable Structure For Point And Distributed Large-Strain Sensing, Chen Zhu, Osamah Alsalman, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

In this paper, we present a truly distributed sensing modality based on a cascaded weak reflector coaxial cable structure (CWR-CCS) for large strain measurements. Compared to an optical fiber, a coaxial cable is much more robust and has a larger strain capability to survive harsh conditions, which may enable important applications in structural health monitoring. By drilling serial shallow holes into a commercial flexible coaxial cable perturbing the local impedance along its axial direction, CWRs along the coaxial cable are introduced due to impedance mismatch, forming the CWR-CCS. Gating a certain number of sequential reflectors in the time-domain reflection signal …

Segmented Fiber Optic Sensors Based On Hybrid Microwave-Photonic Interrogation, Wassana Naku, Osamah Alsalman, Jie Huang, Chen Zhu

Electrical and Computer Engineering Faculty Research & Creative Works

In this paper, we propose and demonstrate a novel concept of segmented fiber optic sensors by integrating the fiber Bragg grating (FBG) reflector modality and a hybrid interrogation technique enabled by microwave photonics. As a proof of concept, a radiofrequency Fabry-Perot interferometer (FPI) based on an optical fiber with two FBGs as the two reflectors of the Fabry-Perot (FP) cavity is constructed. By measuring the frequency response of the FPI device followed by a joint-time-frequency-domain analysis, the interferogram of the FPI in the microwave domain and the time-domain signal of the FBGs can be unambiguously reconstructed. Thus, the two elements …

A Novel Physics-Assisted Genetic Algorithm For Decoupling Capacitor Optimization, Li Jiang, Ling Zhang, Shurun Tan, Da Li, Chulsoon Hwang, Jun Fan, Er Ping Li

Electrical and Computer Engineering Faculty Research & Creative Works

This article proposes a new physics-assisted genetic algorithm (PAGA) for decoupling capacitor (decap) optimization in power distribution networks (PDNs), which is a highly efficient approach to minimizing the number of decaps within an enormous search space. In the proposed PAGA method, the priority of the decap ports is first determined based on their physical loop inductances. Then, an initial solution is quickly obtained by placing decaps sequentially on the port with the highest priority. Subsequently, a GA with prior physical knowledge is developed to find better decap solutions progressively. A port removal scheme that eliminates the low-priority ports and a …

A Segmentation Approach For Predicting Plane Wave Coupling To Pcb Structures, Shengxuan Xia, James Hunter, Aaron Harmon, Ahmed M. Hassan, Victor Khilkevich, Daryl G. Beetner

Electrical and Computer Engineering Faculty Research & Creative Works

Evaluating the far-field radio frequency (RF) susceptibility of electronic devices often depends on extensive testing or full wave simulations. These methods are effective when complete system information is available but require substantial time and resources to evaluate a large number of variations in system configurations, where trace routings, integrated circuit (IC) package styles, trace terminations, arrival angle, and polarization of incoming wave, etc., are varied from one configuration to another. The goal of the following article is to develop simulation techniques for studying the statistical characteristics of coupling to typical printed circuit board (PCB) structures. Simulation time can be reduced …

Controller Area Network With Flexible Data Rate (Can Fd) Eye Diagram Prediction, Junyong Park, Manho Lee, Shinyoung Park, Jonghoon Kim, Joungho Kim, Donghyun Kim

Electrical and Computer Engineering Faculty Research & Creative Works

A method for predicting the eye diagram for a controller area network with a flexible data rate (CAN FD) is proposed in this article. A CAN FD changes a data rate according to the status to overcome the limitation of latency. In other words, when data to be transmitted are accumulated, the CAN FD increases the data rate up to 5 Mb/s. The CAN FD has a bus topology consisting of multiple electronic control units, which results in a significant amount of signal reflection. Thus, the above causes the signal integrity analysis uncertain. To avoid this, this article proposes a …

Adaptive Resilient Control For A Class Of Nonlinear Distributed Parameter Systems With Actuator Faults, Hasan Ferdowsi, Jia Cai, Sarangapani Jagannathan

Electrical and Computer Engineering Faculty Research & Creative Works

This paper presents a new model-based fault resilient control scheme for a class of nonlinear distributed parameter systems (DPS) represented by parabolic partial differential equations (PDE) in the presence of actuator faults. A Luenberger-like observer on the basis of nonlinear PDE representation of DPS is developed with boundary measurements. A detection residual is generated by taking the difference between the measured output of the DPS and the estimated one given by the observer. Once a fault is detected, an unknown actuator fault parameter vector together with a known basis function is utilized to adaptively estimate the fault dynamics. A novel …

Meta-Icvi: Ensemble Validity Metrics For Concise Labeling Of Correct, Under- Or Over-Partitioning In Streaming Clustering, Niklas M. Melton, Sasha Petrenko, Donald C. Wunsch

Electrical and Computer Engineering Faculty Research & Creative Works

Understanding the performance and validity of clustering algorithms is both challenging and crucial, particularly when clustering must be done online. Until recently, most validation methods have relied on batch calculation and have required considerable human expertise in their interpretation. Improving real-time performance and interpretability of cluster validation, therefore, continues to be an important theme in unsupervised learning. Building upon previous work on incremental cluster validity indices (iCVIs), this paper introduces the Meta- iCVI as a tool for explainable and concise labeling of partition quality in online clustering. Leveraging a time-series classifier and data-fusion techniques, the Meta- iCVI combines the outputs …

Equivalent Source Investigation For Pcb Vibration Excited By A Multilayer Ceramic Capacitor, Yifan Ding, Ming Feng Xue, Jianmin Zhang, Xin Hua, Benjamin Leung, Eric A. Macintosh, Chulsoon Hwang

Electrical and Computer Engineering Faculty Research & Creative Works

Multilayer ceramic capacitors (MLCCs) are commonly used on printed circuit board (PCB) power distribution networks (PDN) for decoupling purposes. However, an MLCC can act as a source to excite PCB vibrations due to noise ripples on the power rail. In this letter, four types of equivalent source configurations are studied and compared to represent the excitation of an MLCC on a PCB driven by power rail noise. The corresponding source values are extracted at test-vehicle PCB resonance frequencies. The investigation of the four equivalent source types involves a comparison between simulated and measured PCB vibration velocity responses triggered by MLCC …

Fabrication And Analysis Of A Gas Sensor Utilizing A Fabry-Perot Interferometer With Varied Thicknesses Of Zif-8 Coating On End-Faced Single-Mode Optical Fiber, Nahideh Salehifar, Rex E. Gerald, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

This research investigates the potential of integrating optical fiber and sensitive thin film coating materials to develop diverse chemical sensing platforms. We utilized a layer-by-layer synthesis technique, along with specific pre- post treatment methods, to create highly effective nonporous metal-organic frameworks (MOFs), specifically ZIF-8, ranging from the nanometer scale to the micrometer scale (800 nm to 110 μm). Additionally, we successfully cultivated ZIF-8 on both sides of a single-mode fiber (SMF) with thicknesses of 25 μm and 50 μm. In a separate experiment, we successfully grew ZIF-8 on one side of an optical fiber, achieving a thickness of 10 μm. …

Multimode Fiber-Based Interferometric Sensors With Microwave Photonics, Chen Zhu, Shuaifei Tian, Lingmei Ma, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

Interferometry is one of the most widely used investigative techniques in various fields. With the implementation of interferometry on optical fibers, fiber optic interferometers (FOIs) have gained tremendous growth and advancement in the past four decades and have been explored for measurements of a diverse array of physical, chemical, and biological parameters. FOIs are typically constructed using single-mode fibers (SMFs) and are interrogated in the optical domain using probing light with a tightly controlled state of polarization (SOP), to ensure high-quality interference signals that facilitate sensing applications. The stringent requirement on the single-mode operation, as well as SOP, has hindered …

Investigation Of Intermodal Four-Wave Mixing For Continuous-Wave Photon-Pair Generation, Seyedehnajmeh Montazeri, Md Abu Zobair, Mina Esmaeelpour

Electrical and Computer Engineering Faculty Research & Creative Works

We Experimentally Demonstrate the Various Intermodal and Intramodal Four-Wave Mixing Processes in a Few-Mode Fiber with Three Modes using Non-Degenerate Pumps. We Distinguish the Processes by Calculating their Phase Mismatch and Identify the Intermodal Spontaneous Four-Wave Mixing Process that Generates Entangled Photon Pairs in Various Modes. We Achieve This using Continuous-Wave Beams and the Seeding Technique Due to the Low Efficiency of the Spontaneous Four-Wave Mixing Effect in the Fiber. We Seeded the Stokes and Anti-Stokes Waves and Measured the Spectral Content of Each Mode While Moving the Seed Away from the Perfect Phase-Matched Condition in the Fiber under Test. …

Enhanced Sensitivity And Robustness In An Embeddable Strain Sensor Using Microwave Resonators, Yan Tang, Yizheng Chen, Qi Zhang, Biyao Shi, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

This Paper Introduces A Novel, Cost-Effective, And Durable Strain Sensor With Exceptional Sensitivity And Resolution, Utilizing An Open-Ended Hollow Coaxial Cable Resonator (OE-HCCR). The OE-HCCR Is Characterized By Two Reflective Elements: A Metal Post That Connects The Inner And Outer Conductors At The Signal's Entrance, And A Terminal Flange Near The Coaxial Line's End, Establishing A Variable Gap. The Sensor Employs A Paired Anchor Ring In Conjunction With The Terminal Flange To Transduce And Direct Strain. Variations In The Gap Alter The Resonant Frequency By Modulating The Phase Of The Reflection Coefficient At The Cable's Terminus. Initial Calibration Revealed A …

A Robust Demand Regulation Strategy For Ders In A Single-Controllable Active Distribution Network, Shah Fahad, Arman Goudarzi, Rui Bo, Muhammad Waseem, Rashid Al-Ammari, Atif Iqbal

Electrical and Computer Engineering Faculty Research & Creative Works

Over the past decade, pq regulation schemes for a single-controllable active distribution network (adn) using coordination among a network of virtual synchronous generators (vsgs) have been proposed. However, considering the variable nature of intermittent renewable energy sources (iress), coupling a cluster of iress with the point of common coupling (pcc) of adn could inflict transient issues for the power management of the whole adn. To counter these challenges, the proposed study has three main objectives: 1) to propose a modified mathematical model that represents the apparent resistance-reactance at the pcc of adn in relation to the pq coordination among the …

A Compact And High-Efficiency Antenna Design For Tire Pressure Monitoring System Applications, Lei Deng, Lidong Chi, Francesco De Paulis, Yihong Qi

Electrical and Computer Engineering Faculty Research & Creative Works

This article proposes a novel design for a compact antenna that exhibits high efficiency and low interference and is suitable for tire pressure monitoring systems (TPMSs) based on Bluetooth communication interface at 2.4 GHz. Tires constitute a dissipative environment, where the efficiency of the TPMS is affected by both antenna losses and losses from the tire parts, both conductive and dielectric. This article conducts an analysis and simulation of the electromagnetic (EM) environment of the tire and identifies the optimal polarization and placement position for the TPMS antenna to minimize resonance losses of EM waves within the tire, enhance lateral …