Digital Commons Network^™

Structures Of Channelrhodopsin Paralogs In Peptidiscs Explain Their Contrasting K+ And Na+ Selectivities, Shu Kikuta, Shin Nagayama, Sanae Hasegawa-Ishii

Faculty, Staff and Student Publications

The olfactory epithelium (OE) is directly exposed to environmental agents entering the nasal cavity, leaving OSNs prone to injury and degeneration. The causes of olfactory dysfunction are diverse and include head trauma, neurodegenerative diseases, and aging, but the main causes are chronic rhinosinusitis (CRS) and viral infections. In CRS and viral infections, reduced airflow due to local inflammation, inflammatory cytokine production, release of degranulated proteins from eosinophils, and cell injury lead to decreased olfactory function. It is well known that injury-induced loss of mature OSNs in the adult OE causes massive regeneration of new OSNs within a few months through …

Role Of A Pdlim5:Palmd Complex In Directing Dendrite Morphology, Yogesh Srivastava, Maxsam Donta, Lydia L Mireles, Adriana Paulucci-Holthauzen, M Neal Waxham, Pierre D Mccrea

Faculty, Staff and Student Publications

Neuronal connectivity is regulated during normal brain development with the arrangement of spines and synapses being dependent on the morphology of dendrites. Further, in multiple neurodevelopmental and aging disorders, disruptions of dendrite formation or shaping is associated with atypical neuronal connectivity. We showed previously that Pdlim5 binds delta-catenin and promotes dendrite branching. We report here that Pdlim5 interacts with PalmD, a protein previously suggested by others to interact with the cytoskeleton (e.g.,

Anticancer Effects Of Wild Baicalin On Hepatocellular Carcinoma: Downregulation Of Akr1b10 And Pi3k/Akt Signaling Pathways, Longjun Sun, Wenjuan Chen, Peixi Zhao, Bin Zhao, Guangyan Lei, Le Han, Yili Zhang

Faculty, Staff and Student Publications

ntroduction

Hepatocellular carcinoma (HCC) is a common and deadly malignancy. Traditional Chinese medicine, such as the compound Astragalus (wild Baicalin), has shown promise in improving outcomes for HCC patients. This study aimed to investigate the effects of wild Baicalin on the human hepatoma cell line HepG2 and elucidate the underlying mechanisms, particularly the role of the AKR1B10 and PI3K/AKT signaling pathways.

Methods

HepG2 cells were treated with varying concentrations of wild Baicalin. Cell proliferation, apoptosis, migration, invasion, and cell cycle were evaluated using CCK-8, flow cytometry, scratch, Transwell, and clonogenic assays, respectively. Transcriptome sequencing was performed to analyze gene expression …

Simultaneous Submission Of Seven Ctsa Proposals: Um1, K12, R25, T32-Predoctoral, T32-Postdoctoral, And Rc2: Strategies, Evaluation, And Lessons Learned, Carolina Lema, Kwai Wa Cheng, Delanderia M Anderson, Charles C Miller, Daniel D Karp, David D Mcpherson, Satya Sree N Kolar

Faculty, Staff and Student Publications

Translation is the process of turning observations in the research laboratory, clinic, and community into interventions that improve people's health. The Clinical and Translational Science Awards (CTSA) program is a National Center for Advancing Translational Sciences (NCATS) initiative to advance translational science and research. Currently, 64 "CTSA hubs" exist across the nation. Since 2006, the Houston-based Center for Clinical Translational Sciences (CCTS) has assembled a well-integrated, high-impact hub in Texas that includes six partner institutions within the state, encompassing ∼23,000 sq. miles and over 16 million residents. To achieve the NCATS goal of "more treatments for all people more quickly," …

“Just Holding That Space”: Using Culturally Relevant Pedagogy To Create Counterspaces For Black College Students In Aanapisi/Hsi Classrooms, Nicholas B. Lacy, Yea-Wen Chen, Damariyé L. Smith

Journal of Communication Pedagogy

Black college students continue to face the specter of anti-Blackness which creates additional barriers to success and flourishing in higher education. This study investigates how instructors in higher education can provide racial equity to Black students in AANAPISI/HSI classrooms through counterspaces. We use culturally relevant pedagogy to investigate the experiences of 21 Black college students at an AANAPISI/HSI to understand better how higher education instructors can utilize counterspaces, places where Black college students can challenge dominant discourses and create a collegial learning environment. We identified three counterspace themes: (1) Mitigate Eurocentric Pedagogy, (2) Employ Black and Critical Scholarship, and (3) …

You Don’T Have To Be Their Best Friend: Complicating The Instructor-Student Relationship Through A Mixed-Method Typology, Jessalyn I. Vallade, Kyle Rudick

Journal of Communication Pedagogy

The purpose of this study was to explore the nuances of instructor-student relationships with a nationally representative sample of students. Participants were randomly assigned to describe relationships with their best, worst, and/or last instructor and rate their satisfaction with each relationship, and the level of closeness with the instructor. Coding of student descriptions revealed 13 themes, organized into six pairs of constructive/destructive relationship anchors and one neutral category (Professional Relationship). Importantly, professional relationships were not as close as constructive relationships but were equally satisfying, indicating the closeness in instructor-student relationships has diminishing returns. Results are discussed in the context of …

Beyond Labor: The Lingering Impact Of Childbirth On Women’S Health, Alisha Riggins, Emmanuela Nwaonumah, Tobi Oloyede, Susmita Dey, Joanne Chopak-Foss, Logan Cowan

Eagles Talking About the Public’s Health

No abstract provided.

2024 Spring Commencement, Georgia Southern University

Commencement Programs

No abstract provided.

2024 Fall Commencement, Georgia Southern University

Commencement Programs

No abstract provided.

Eagle Accountant - 2024, Georgia Southern University

Eagle Accountant

• Accounting Advisory Council
• Accreditation & Rankings
• Cover Story - The Titan 
• Student Spotlight:  Across the Atlantic to Georgia Southern
• Student Spotlight: Solving the Puzzle: My Journey at Georgia Southern
• Fraud & Forensic Accounting 
• A Standout Life: Julian Deal 
• Faculty Highlights 
• Faculty Service Spotlight 
• Faculty Research Spotlight 
• Student Ordanizations & Activities 
• New MAcc Program Option 
• Faculty Awards, Service, & Publications  
• Alumni Notes & Obituaries 

Assessing The Happiness Of University Of The Philippines Los Baños Faculty: Insights Into Academic Well-Being, Joyce Dl. Grajo, Nancy A. Tandang, Roselle V. Collado, Reanne Len C. Arlan, Maurice C. Borromeo, Edrun R. Gayosa, John Lorenzo A. Yambot

Journal Article

Faculty happiness is a key factor influencing productivity, engagement, and institutional commitment. This study examined the level of happiness among faculty members at the University of the Philippines Los Baños using an adopted instrument designed to yield a happiness index score. The self-report survey assessed dimensions such as psychological well-being, time balance, workplace environment, and career growth opportunities. Descriptive and correlation analyses were conducted to explore associations between faculty happiness and various personal and work- related factors. Specifically, Spearman's rank-order and point-biserial correlation coefficients were used to correlate happiness score with ordinal and dichotomous factors, respectively. Findings indicate that faculty …

From Lived Experiences To Social Activism: Latino Fraternity Brothers Critical Service To The Latinx Community, Regina L. Suriel, James Martinez, Christian Bello Escobar, Jamie L. Workman

Journal of Higher Education & Student Affairs

Colleges and universities are seeing growth of Latinx students actively engaged in Greek life. In this study, six Latino participants share their testimonios as members of different Chapters of a Latinx Greek Letter Organization (LGLO) nestled within Predominantly White Institutions located in the state of Georgia, USA. Informed by LatCrit theory, this qualitative study uses member’s testimonios to shed light on their varied and sometimes politically charged and racist lived experiences. The researchers draw on these experiences to show how the LGLO supported these members’ character and leadership development and their desire and commitment to critical service and socially just …

Understanding The Role Of Cultural Competence In Peer Mentorship Programs For International Students: A Student Development Theory Perspective, Nikheal Patel, Daniel Calhoun, Steven Tolman

Journal of Higher Education & Student Affairs

International students often face challenges while pursuing higher education in a foreign country. These challenges can negatively impact their sense of belonging and community, resulting in social disconnection. Examining the role of culturally competent peer mentoring programs for international students can foster a sense of belonging among international students. Peer mentorship may provide international students with a supportive environment and community, helping them navigate university life. In contrast, student development theory can inform the design of programs and services that support international students in their transition to American higher education. These strategies can create a more inclusive and welcoming environment …

From Private To Public: Lateral Transfer Student Experiences, Melissa P. Stough, Diane C. Elliott

Journal of Higher Education & Student Affairs

The phenomenon of student movement between higher education institutions has received considerable attention due to its widespread occurrence and impact on academic trajectories. While extensive research has focused on vertical transfer, such as transitions from community colleges to four-year institutions, less scrutiny has been directed towards lateral transfer, involving shifts between institutions at similar academic levels. This study aims to fill this gap by examining the factors influencing lateral transfer, specifically from private four-year colleges to public four-year institutions. The COVID-19 pandemic has heightened interest in this understudied area, with indications of increased lateral transfers in its aftermath. Leveraging data …

Predicting Retention, Progression, And Graduation Of First-Time Freshmen Students, Brynn L. Munro, Juliann Sergi Mcbrayer, Antonio P. Gutierrez De Blume, Pamela Wells

Journal of Higher Education & Student Affairs

Currently, roughly one third of college students fit the federal government’s definition of first-generation college student status, meaning that neither parent has earned a baccalaureate degree (RTI International, 2023). This study utilized archival data at an access institution in the southeastern United States in a causal comparative study using binary logistic regression analysis to determine if first-generation college student status, gender, socioeconomic status, and academic preparedness are predictors for six-year graduation rates. Findings from this quantitative study determined that gender, socioeconomic status, and academic preparedness were significant predictors for graduation within six years of matriculation at the institution. A future …

Up Los Baños Journal, Volume 22 - Regular Issue

U.P. Los Baños Journal

UP Los Baños Journal, Volume 22 - Regular Issue

Improving Field Education For Social Work In Vietnam: Intern Supervisors’ Perspectives Of The Current State And Potential Solutions, Megan Aikawa, Meekyung Han, Trang T. Nguyen, Linh Dinh, Minh Thanh Bui

Faculty Research, Scholarly, and Creative Activity

Research has identified challenges associated with the implementation of competency-based social work field education in Vietnam. However, there is limited information available from intern supervisors, who have unique perspectives at the crux of social work training and service delivery. An exploratory phenomenological qualitative approach was used to explore their experiences and perceptions through online interviews. Four categories were identified: diverse implementation of a common framework, rudimentary expectations and activities, challenges to implementation, and opportunities for improvement. These findings suggest that a multidimensional approach is needed, including improved collaborations between field agencies and universities to empower students, intern supervisors, and faculty.

Advance (Spring 2024), Georgia Southern Division Of Continuing And Professional Education

Division of Continuing & Professional Education

No abstract provided.

Western Pacific K-12 Educators’ Adoption Of Digital Game-Based Learning, Lorraine Raqueño Catienza

Theses and Dissertations

Western Pacific educational institutions are investing heavily in technology in classrooms to meet the needs of K-12 students. Measuring the effective use of digital technologies in the learning environment has become a routine part of monitoring and evaluating classroom instruction. One area of technology integration that has seen tremendous growth is digital game-based learning (DGBL). The researcher is interested in examining K-12 western Pacific teachers’ willingness to adopt DGBL through a modified Technology Acceptance Model. This study aims to examine the extent to which teachers’ perceived usefulness, perceived ease of use, and technology self-efficacy effects attitude toward adopting DGBL methods. …

Examining The Effects Of Video Self-Modeling With Goal Setting On Third-Grade Students' Oral Reading Fluency, Sara Sleiman Tellaoui

Electronic Theses & Dissertations (2024 - present)

Video self-modeling (VSM) is an intervention based on Bandura’s (1999) theory of observational learning, which assumes that children learn a target behavior by observing a more competent model. VSM is assumed to provide an effective model from which children can learn given that the learner and model are the same person but differ only in their skills. More recently, studies have explored the effectiveness of VSM as an intervention for oral reading fluency (ORF) and showed promising results. Goal setting (GS) is another intervention that has been found to be effective in increasing students’ performance by motivating them to meet …

Exploring The Epitranscriptomic Response To Senolytics And Senomorphs In Cellular Models Of Aging, Emily Benson

Electronic Theses & Dissertations (2024 - present)

In senescence that occurs with aging, cells stop dividing and initiate a pro-inflammatory program called the senescence associated secretory phenotype (SASP). SASP can lead to cell damage and has been linked to age-related conditions such as cancer, diabetes, osteoporosis, cardiovascular disease, Alzheimer’s disease, and osteoarthritis. The epitranscriptome regulates translation through post-transcriptional RNA modifications and can control when and how much of protein synthesis occurs. Several tRNA modifications that include 5-methoxycarbonylmethyl (mcm⁵U), 5-methoxycarbonylmethyl-2-thiouridine (mcm⁵s²U), and mcm⁵Um (5-methoxycarbonylmethyl-2′-O-methyluridine) are linked to the translation of enzymes involved in the detoxification of reactive oxygen species (ROS), …

Studies In Three-Component Modification Of Lysine, Investigating Reversible Potential Of An Intricate Bicyclo [3.3.1] Nonane Scaffold, Ryan Bartlett

Electronic Theses & Dissertations (2024 - present)

Synthesis of small-molecule conjugates capable of selective attachment to a peptide/protein backbone paves way for new therapeutic applications of protein modification. Sufficient inhibition or installation of function requires extensive design so the compound may identify and attach to the intended site. The utility of such an approach has prompted a number of applicable strategies and has rendered the development of new modification scaffolds less necessary. On the other hand, covalent modification to the biologics with ability to remove the conjugate via stimulus is underdeveloped, amplifying a current need to investigate the reversible potential for conjugation and deconjugation techniques in regard …

Re-Globalizing Yorkville: The Languages On Shop Signs In A Non-Migrant Neighborhood, Lisabeth G. Dashman

Electronic Theses & Dissertations (2024 - present)

The term “linguistic landscape” is used to describe the usage and placement of language in public places of a specific geographic area, such as on buildings, street names, pedestrian notices, vehicular warnings, and advertising billboards. Studies of a space’s linguistic landscape typically involve an accounting and analysis of the visible signs and/or the presentation of bystanders’ or researchers’ thoughts and observations. This study instead probes the intentions of the sign creators: the owners of the façade sign and the business it advertises. The façade sign, often called the shop sign, is frequently the first image for a business that a …

The Importance Of Ice Microphysics In Storm Electrification, Yichen Cai

Electronic Theses & Dissertations (2024 - present)

Evanescent but powerful, lightning is the vast scale release of storm energy from accumulation of minuscule cloud particle interactions. Although lightning occurrence seems random, thunderstorms “electrify” themselves in methodical ways and show structured patterns. This study explores the role of ice microphysics in thunderstorm charging and discharge through numerical simulation.

A squall line has been simulated ideally and realistically with generally consistent conclusions. Drastically different amount of lightning was produced when using three different microphysical models: Depending on the choice of charging scheme, the National Severe Storm Laboratory (NSSL) two-moment model appropriately captures or overestimate the amount observed by the …

Protecting Foreign Victims Of Trafficking In Iceland: An Interpretive Analysis Of Policy Efforts, Hlin Saethorsdottir

Electronic Theses & Dissertations (2024 - present)

Social justice and human rights are fundamental principles of social work. Today’s globalized world requires social workers to expand their local perspectives and to be alert to the negative sides of globalization, such as trafficking in person (TIP), which affects all countries around the world. TIP is a severe form of exploitation and a grave human rights violation (Jones et al., 2007). Iceland has been categorized as a transit and destination country for foreign victims who are mainly trafficked for sexual and labor exploitation (U.S. Department of State, 2016b).

Although much has been written on TIP, some scholars have pointed …

A Concept Of Producing Aluminum In-Situ On The Moon Through Molten Salt Electrolysis, Jacob N. Ortega, Jeffrey Smith, Fateme Rezaei, David Bayless, William Schonberg, Daniel Stutts, Daoru Han

Materials Science and Engineering Faculty Research & Creative Works

This paper presents a concept of producing aluminum in-situ on the lunar surface, namely, the Lunar In-Situ Aluminum Production through Molten Salt Electrolysis (LISAP-MSE) method developed at Missouri University of Science and Technology. This paper aims to demonstrate the use of electro-deoxidation to reduce aluminum oxide (i.e., alumina) into aluminum and oxygen gas via electrolysis in a molten salt bath for the production of aluminum on the Moon. It is shown that with a steady supply of hydrogen chloride, this in-situ resource utilization (ISRU) method could supply several necessary materials consumed in the electro-deoxidation process except hydrogen chloride to produce …

Descriptive Statistical Analysis Of Experimental Data For Wettability Alteration With Smart Water Flooding In Carbonate Reservoirs, Muhammad Ali Buriro, Mingzhen Wei, Baojun Bai, Ya Yao

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Smart water flooding is a promising eco-friendly method for enhancing oil recovery in carbonate reservoirs. the optimal salinity and ionic composition of the injected water play a critical role in the success of this method. This study advances the field by employing machine learning and data analytics to streamline the determination of these critical parameters, which are traditionally reliant on time-intensive laboratory work. the primary objectives are to utilize data analytics to examine how smart water flooding influences wettability modification, identify key parameter ranges that notably alter the contact angle, and formulate guidelines and screening criteria for successful lab design. …

Progress Of Lisap-Mse: A Concept Of Producing Aluminum In-Situ On The Moon Through Molten Salt Electrolysis, Jacob N. Ortega, David Bayless, Daniel Stutts, Daoru Han, Todd P. Sander, Jeffrey Smith, Fateme Rezaei, William Schonberg

Mechanical and Aerospace Engineering Faculty Research & Creative Works

This paper presents a concept of producing aluminum in-situ on the lunar surface, namely, the Lunar In-Situ Aluminum Production through Molten Salt Electrolysis (LISAP-MSE) method developed at Missouri University of Science and Technology. This paper aims to demonstrate the use of electro-deoxidation to reduce aluminum oxide (i.e., alumina) into aluminum and oxygen gas via electrolysis in a molten salt bath for the production of aluminum on the Moon. It is shown that with a steady supply of hydrogen chloride, this in-situ resource utilization (ISRU) method could supply several necessary materials consumed in the electro-deoxidation process except hydrogen chloride to produce …

Prediction Of Carbonation Capacity Of Scms Using Ensemble Learning Method, Kangyi Cai, Jian Liu, Edward Mwanza, Mahelet G. Fikru, Hongyan Ma, Donald C. Wunsch

Economics Faculty Research & Creative Works

The utilization of supplementary cementitious materials (SCMs) subjected to carbonation processing represents a viable strategy to mitigate anthropogenic CO₂ emissions associated with concrete production, potentially contributing to the achievement of carbon neutrality. However, existing studies have limitations in effectively predicting the varying carbonation capacities of different SCMs, a gap that this research aims to address. Recent research efforts focused on the carbonation of waste-material-sourced SCMs are reviewed, along with a comparative discussion on diverse carbonation methods. A detailed data set encapsulating the properties of SCMs, and carbonation configurations was compiled. At the same time, six ensemble learning models were …

Defects Detection Of Concrete Bridge Decks Using Uav-Based Infrared Thermography, H. B. Zhang, Z. Zhou, G. Chen

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Concrete bridges are vulnerable to both natural and man-made disasters, as well as aging and deterioration processes throughout their lifespan. Timely detection of defects in concrete structures is crucial for repair and decision-making purposes. However, traditional methods like visual inspection are time-consuming and expensive. Unmanned aerial vehicles (UAVs) equipped with infrared thermography (IRT) offer an efficient and cost-effective solution for detecting defects in concrete structures. This study presents passive and active IRT techniques for detecting common concrete defects, such as delamination and cracks. Principle and methods for quantifying these defects and evaluating the extent of damage are introduced. Experiments are …