Digital Commons Network^™

Gene Content, Phage Cycle Regulation Model And Prophage Inactivation Disclosed By Prophage Genomics In The Helicobacter Pylori Genome Project, Filipa F Vale, Richard J Roberts, Ichizo Kobayashi, M Constanza Camargo, Charles S Rabkin, Hpgp Research Network

Faculty, Staff and Students Publications

Prophages can have major clinical implications through their ability to change pathogenic bacterial traits. There is limited understanding of the prophage role in ecological, evolutionary, adaptive processes and pathogenicity of Helicobacter pylori, a widespread bacterium causally associated with gastric cancer. Inferring the exact prophage genomic location and completeness requires complete genomes. The international Helicobacter pylori Genome Project (HpGP) dataset comprises 1011 H. pylori complete clinical genomes enriched with epigenetic data. We thoroughly evaluated the H. pylori prophage genomic content in the HpGP dataset. We investigated population evolutionary dynamics through phylogenetic and pangenome analyses. Additionally, we identified …

The Impact Of Obesity-Associated Glycine Deficiency On The Elimination Of Endogenous And Exogenous Metabolites Via The Glycine Conjugation Pathway, Hong Chang Tan, Jean W Hsu, E Shyong Tai, Shaji Chacko, Jean-Paul Kovalik, Farook Jahoor

Faculty, Staff and Students Publications

BACKGROUND: Glycine is an integral component of the human detoxification system as it reacts with potentially toxic exogenous and endogenously produced compounds and metabolites via the glycine conjugation pathway for urinary excretion. Because individuals with obesity have reduced glycine availability, this detoxification pathway may be compromised. However, it should be restored after bariatric surgery because of increased glycine production.

OBJECTIVE: To examine the impact of obesity-associated glycine deficiency on the glycine conjugation pathway. We hypothesize that the synthesis rates of acylglycines from endogenous and exogenous sources are significantly reduced in individuals with obesity but increase after bariatric surgery.

METHODS: We …

Balancing Honest Assessment And Compassion For Learners Experiencing Burnout: A Workshop And Feedback Tool For Clinical Teachers, Gal Barak, Dana Foradori, H Barrett Fromme, Linessa Zuniga, Andrea Dean

Faculty, Staff and Students Publications

INTRODUCTION: Burnout in medical trainees challenges their work effectiveness and impedes their ability to learn. Teachers in the clinical learning environment (CLE) are well situated to identify burnout and are often responsible for learner assessment.

METHODS: We developed a workshop to improve clinical teachers' identification and understanding of learner burnout while empowering them to provide constructive feedback and support. Building on best-practice feedback techniques and utilizing the Maslach Burnout Inventory (MBI) as a framework, we designed the GetINBurnOUT method to provide feedback and support for learners experiencing burnout. Applying Kern's six-step approach to curriculum development, we created and implemented a …

Spatial Transcriptomics Resolve An Emphysema-Specific Lymphoid Follicle B Cell Signature In Chronic Obstructive Pulmonary Disease, Joselyn Rojas-Quintero, Scott A Ochsner, Felicia New, Prajan Divakar, Chen Xi Yang, Tianshi David Wu, Jerid Robinson, Darshan Shimoga Chandrashekar, Nicholas E Banovich, Ivan O Rosas, Maor Sauler, Farrah Kheradmand, Amit Gaggar, Camilla Margaroli, Raul San Jose Estepar, Neil J Mckenna, Francesca Polverino

Faculty, Staff and Students Publications

Rationale

Within chronic obstructive pulmonary disease (COPD), emphysema is characterized by a significant yet partially understood B cell immune component.

Objectives

To characterize the transcriptomic signatures from lymphoid follicles (LFs) in ever-smokers without COPD and patients with COPD with varying degrees of emphysema.

Methods

Lung sections from 40 patients with COPD and ever-smokers were used for LF proteomic and transcriptomic spatial profiling. Formalin- and O.C.T.-fixed lung samples obtained from biopsies or lung explants were assessed for LF presence. Emphysema measurements were obtained from clinical chest computed tomographic scans. High-confidence transcriptional target intersection analyses were conducted to resolve emphysema-induced transcriptional networks. …

Effects And Plasma Proteomic Analysis Of Glp-1ra Versus Cpa/Ee, In Combination With Metformin, On Overweight Pcos Women: A Randomized Controlled Trial, Mingyu Liao, Xing Li, Hao Zhang, Ling Zhou, Liu Shi, Weixin Li, Rufei Shen, Guiliang Peng, Huan Zhao, Jiaqing Shao, Xiujie Wang, Zheng Sun, Hongting Zheng, Min Long

Faculty, Staff and Students Publications

PURPOSE: Polycystic ovary syndrome (PCOS) is characterized by reproductive dysfunctions and metabolic disorders. This study aims to compare the therapeutic effectiveness of glucagon-like peptide-1 receptor agonist (GLP-1RA) + Metformin (Met) versus cyproterone acetate/ethinylestradiol (CPA/EE) + Met in overweight PCOS women and identify potential proteomic biomarkers of disease risk in women with PCOS.

METHODS: In this prospective, open-label randomized controlled trial, we recruited 60 overweight PCOS women into two groups at a 1:1 ratio to receive CPA/EE (2 mg/day: 2 mg cyproterone acetate and 35-μg ethinylestradiol,) +Met (1500 mg/day) or GLP-1 RA (liraglutide, 1.2-1.8 mg/day) +Met (1500 mg/day) for 12 weeks. …

Liver Directed Adeno-Associated Viral Vectors To Treat Metabolic Disease, Marcel A Chuecos, William R Lagor

Faculty, Staff and Students Publications

The liver is the metabolic center of the body and an ideal target for gene therapy of inherited metabolic disorders (IMDs). Adeno-associated viral (AAV) vectors can deliver transgenes to the liver with high efficiency and specificity and a favorable safety profile. Recombinant AAV vectors contain only the transgene cassette, and their payload is converted to non-integrating circular double-stranded DNA episomes, which can provide stable expression from months to years. Insights from cellular studies and preclinical animal models have provided valuable information about AAV capsid serotypes with a high liver tropism. These vectors have been applied successfully in the clinic, particularly …

Co-Expression Of Prepulse Inhibition And Schizophrenia Genes In The Mouse And Human Brain, Lillian Garrett, Dietrich Trümbach, Donghyung Lee, Silvia Mandillo, Rodney Samaco, Ann M Flenniken, Michelle Stewart, Impc Consortium, Jacqueline K White, Colin Mckerlie, Lauryl M J Nutter, Igor Vukobradovic, Surabi Veeraragavan, Lisa Yuva, Jason D Heaney, Mary E Dickinson, Hamid Meziane, Yann Hérault, Sara Wells, K C Kent Lloyd, Lynette Bower, Louise Lanoue, Dave Clary, Annemarie Zimprich, Valerie Gailus-Durner, Helmut Fuchs, Steve D M Brown, Elissa J Chesler, Wolfgang Wurst, Martin Hrabě De Angelis, Sabine M Hölter

Faculty, Staff and Students Publications

Schizophrenia is a complex psychiatric disorder with genetic and phenotypic heterogeneity. Accumulating rare and genome-wide association study (GWAS) common risk variant information has yet to yield robust mechanistic insight. Leveraging large-scale gene deletion mouse phenomic data thus has potential to functionally interrogate and prioritize human disease genes. To this end, we applied a cross-species network-based approach to parse an extensive mouse gene set (188 genes) associated with disrupted prepulse inhibition (PPI), a Schizophrenia endophenotype. Integrating PPI genes with high-resolution mouse and human brain transcriptomic data, we identified functional and disease coherent co-expression modules through hierarchical clustering and weighted gene co-expression …

Scan-Less Microscopy Based On Acousto-Optic Encoded Illumination, Andrea Marchese, Pietro Ricci, Peter Saggau, Martí Duocastella

Faculty, Staff and Students Publications

Several optical microscopy methods are now available for characterizing scientific and industrial processes at sub-micron resolution. However, they are often ill-suited for imaging rapid events. Limited by the trade-off between camera frame-rate and sensitivity, or the need for mechanical scanning, current microscopes are optimized for imaging at hundreds of frames-per-second (fps), well-below what is needed in processes such as neuronal signaling or moving parts in manufacturing lines. Here, we present a scan-less technology that allows sub-micrometric imaging at thousands of fps. It is based on combining a single-pixel camera with parallelized encoded illumination. We use two acousto-optic deflectors (AODs) placed …

Pretreatment Characteristics Associated With Symptom Reduction During Group Cognitive Processing Therapy Versus Exposure Therapy For Ptsd: An Exploratory Study Of Veterans, Christopher Hunt, Brooks Casas, Pearl H Chiu, Lia J Smith, Laura Priorello, Kelly Lee, Matthew Estey, Mary R Newsome, M Wright Williams

Faculty, Staff and Students Publications

Exposure and cognitive-based therapies are both effective for PTSD, but knowledge of which intervention is best for which patient is lacking. This lack of knowledge is particularly noticeable for group treatments, as no study has examined whether responses to different group therapies are associated with different pretreatment characteristics. Here, we explored whether pretreatment levels of three types of psychological characteristics-PTSD symptom clusters, posttraumatic cognitions, and emotion regulation difficulties-were associated with symptom reduction during group-delivered cognitive versus exposure-based PTSD treatment. Participants were Veterans with PTSD drawn from two previous clinical trials: one of group CPT (GCPT;

Lack Of Association Of A1c With Postoperative Complications In Children With Type 1 Or Type 2 Diabetes, Grace Kim, Mckenna C Richards, Abigail B Smith, Kathleen M Strybos, Xiaofan Huang, Kristen Staggers, Stephen A Stayer, Rahul G Baijal

Faculty, Staff and Students Publications

Not meeting recommended A1C targets may be associated with postoperative complications in adults, but there are no studies reporting on the relationship between preoperative A1C and postoperative complications in children with type 1 or type 2 diabetes. The objective of this study was to determine whether elevated A1C levels were associated with an increased incidence of postoperative complications in children with diabetes presenting for elective noncardiac surgery or diagnostic procedures. It found no such association, suggesting no need to delay elective surgery in children with diabetes until A1C is optimized.

Neural Correlates Of Executive Functioning In Preschool Children, Michelle Lobermeier

Master's Theses and Doctoral Dissertations

Healthy development of executive functioning (EF) provides an important foundation for emotional and behavioral regulation as well as academic success. Preschool is a time of rapid EF development, making this a target age group for identifying and intervening on EF weaknesses. Since EF has been historically difficult to behaviorally measure in preschoolers, the current study explores neural correlates of EF as another method by which to understand its development. The goal of the present study is to explore associations between resting state electroencephalography (EEG) power (i.e., theta, alpha, beta) and EF ability in preschool and examine how early regulatory ability …

Role Of Apolipoprotein B In The Clinical Management Of Cardiovascular Risk In Adults: An Expert Clinical Consensus From The National Lipid Association, Daniel E Soffer, Nicholas A Marston, Kevin C Maki, Terry A Jacobson, Vera A Bittner, Jessica M Peña, George Thanassoulis, Seth S Martin, Carol F Kirkpatrick, Salim S Virani, Dave L Dixon, Christie M Ballantyne, Alan T Remaley

Faculty, Staff and Students Publications

This National Lipid Association (NLA) Expert Clinical Consensus provides an overview of the physiologic and clinical considerations regarding the role of apolipoprotein B (apoB) measurement to guide clinical care based on the available scientific evidence and expert opinion. ApoB represents the total concentration of atherogenic lipoprotein particles in the circulation and more accurately reflects the atherogenic burden of lipoproteins when compared to low-density lipoprotein cholesterol (LDL-C). ApoB is a validated clinical measurement that augments the information found in a standard lipoprotein lipid panel; therefore, there is clinical value in using apoB in conjunction with a standard lipoprotein lipid profile when …

Understanding Prescribing Practices And Patient Experiences With Renin Angiotensin System Inhibitors Use In Chronic Kidney Disease: A Qualitative Study, Jennifer Arney, L Parker Gregg, Sheena Wydermyer, Michael A Herrera, Peter A Richardson, Michael E Matheny, Julia M Akeroyd, Glenn T Gobbel, Adriana Hung, Salim S Virani, Sankar D Navaneethan

Faculty, Staff and Students Publications

Introduction: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) improve outcomes but are underutilized in patients with chronic kidney disease (CKD). Little is known about reasons for discontinuation and lack of reinitiating these medications. We aimed to explore clinicians' and patients' experiences and perceptions of ACEI/ARB use in CKD.

Methods: A multi-profession sample of health care clinicians and patients with documented ACEI/ARB-associated side effects in the past 6 months. Participants were recruited from 2 Veterans Affairs healthcare systems in Texas and Tennessee. A total of 15 clinicians and 10 patients completed interviews. We used inductive and deductive qualitative data …

Ginkgo Biloba For Tardive Dyskinesia And Plasma Mnsod Activity: Association With Mnsod Ala-9val Variant: A Randomized, Double-Blind Trial, Dongmei Wang, Yang Tian, Jiajing Chen, Rongrong Zhu, Jiaxin Li, Huixia Zhou, Dachun Chen, Li Wang, Thomas R Kosten, Xiang-Yang Zhang

Faculty, Staff and Students Publications

Background: Excessive free radicals are implicated in the pathophysiology of tardive dyskinesia (TD), and Ginkgo biloba extract (EGb761) scavenges free radicals, thereby enhancing antioxidant enzymes such as mitochondrial manganese superoxide dismutase (MnSOD). This study examined whether EGb761 treatment would improve TD symptoms and increase MnSOD activity, particularly in TD patients with specific MnSOD Val-9Ala genotype.

Methods: An EGb761 (240 mg/day) 12-week double-blind clinical trial with 157 TD patients was randomized. The severity of TD was measured by the Abnormal Involuntary Movement Scale (AIMS) and plasma MnSOD activity was assayed before and after 12 weeks of treatment. Further, in an expanded …

Centering The Needs Of Language Learners Within Educators’ Professional Learning And Development: An Investigation Of Teachers’ Perceptions And Experiences In Meeting The Needs Of Language Learners, Kimberly Tsukiyama

Master's Theses and Doctoral Dissertations

This qualitative study explores K-12 classroom teachers' perceptions and experiences in meeting the needs of language learners, specifically English language learners (ELLs) and dual-language learners (DLLs). Addressing two main research questions, it investigated how teachers' preservice learning and development prepared them for instructing language learners and identified preparatory experiences and professional learning considered beneficial and critical to their development in this area. Through surveys, teacher interviews, and classroom observations, the study highlighted challenges faced by teachers in settings with diverse language populations, including native Japanese, Spanish, and Arabic speakers, as well as native English speakers learning a second language. It …

Loan Debt Burden, Student Experiences, And Livelihood: A Study Examining Relationships Between Students’ Education Costs, Financial Viability, And Life Impact, Christa A. Reid

Master's Theses and Doctoral Dissertations

This dissertation investigates the complex connections among loan debt burden, student experiences, and post-bachelor’s outcomes, situated within the framework of systemic disparities in educational funding and opportunities. It identifies declines in state funding across educational levels as a systemic and politicized issue, disproportionately affecting students in underserved and underresourced school districts. The study emphasizes the impact of systemic racism and policymaking in perpetuating poverty through higher education, emphasizing the need for equitable policy establishment. Economic downturns and reduced higher education funding necessitate the exploration of alternative revenue streams, such as endowed funds and fundraising efforts, to prevent increased tuition costs …

Looking For Love On A Chilly Night: The Colorado Brown Tarantula Mating Season, Dallas Haselhuhn

Master's Theses and Doctoral Dissertations

Aphonopelma hentzi is the most widespread and abundant tarantula species in the United States. While a distinct mating season is observed, it has not been well studied and the environmental drivers for the mating season are unknown. By conducting daily surveys on a peripheral population within Southeast Colorado, between August and November 2022, I found that after the first significant temperature drop, the number of mate-seeking males was significantly higher than prior to this temperature event. Mate-seeking males were significantly correlated with a drop in the water vapor pressure gradient, a rarely used biological metric for assessing potential water loss …

Identifying The Origins Of Business’ Data Breaches Utilizing Covert Timing Channels, Gayle L. Frisbie

Master's Theses and Doctoral Dissertations

Cybersecurity events and data breaches are on the rise and are very costly to businesses. Businesses rely on connectivity and information systems to conduct business, yet those same information systems can be breached and the organization's data exposed. Today, there is a heavy reliance of organizations upon network connections to connect the entire organization in order to conduct business efficiently and from multiple locations. Covert timing channels are a cybersecurity attack method in which malicious actors embed privileged information into normal network traffic without authorization. Malicious actors, by carefully manipulating timing patterns in covert timing channels, can create a hidden …

African American Adolescent Suicidality And Prevention From An Urban School Counselor Perspective, Shannon Franklin

Master's Theses and Doctoral Dissertations

African American adolescent suicidality has become more prevalent, and urban school counselors are positioned uniquely to intervene. This research studied the overarching societal factors in the sociocultural, economic, and political spheres that influence increased suicidality behaviors in African American adolescents from the perspective of urban school counselors. The focus of this research was to hear the lived experiences of urban school counselors regarding the impact of racial discrimination on African American adolescent suicidality. The two theoretical frameworks that were used to support this study are the world-systems analysis theory and critical race theory. This study took a qualitative phenomenological approach …

Assessment Of The Ecological Integrity Of Two Wetland Sites Within Eastern Michigan University’S Fish Lake Environmental Education Center (Fleec), Brianna Rice

Master's Theses and Doctoral Dissertations

Wetland ecosystems function as reservoirs of biodiversity for both terrestrial and aquatic organisms, and are among the most vulnerable ecosystems to degradation. The ecological integrity of two wetlands at Eastern Michigan University’s Fish Lake Environmental Education Center, a bog and one vernal pool, was assessed. Plant species richness was used to conduct Floristic Quality Assessments (FQA) using the coefficient of conservatism and wetland indicator status for each species. The Michigan Rapid Assessment Method (MiRAM) was conducted as a more comprehensive assessment of each ecosystem. The bog had an FQA of 31.6 and a MiRAM: 81/100, representing high-quality wetland conditions. The …

In It And Of It: A Black Principal’S Self-Examination Of Anti-Blackness And Critical Leadership Praxis, Donya Odom

Master's Theses and Doctoral Dissertations

Narrative inquiry is my research method, and my goal is to validate the use of narratives, including my reflective memos, journal reflections, and interpretations of various artifacts that share my students' experiences. As a Black woman and an educator, I emphasize the importance of culturally responsive school leadership for K-12 principals, which includes fostering connections with and amplifying the voices of marginalized Black students to improve their academic engagement. My study also highlights my experiences' critical role in building positive relationships with the school community, particularly in enhancing Black students' climate and cultural experiences. With this study, I shed light …

Towards A Transparency-Based, Value-Sensitive Design Solution For Bias In Self-Driving Cars: An Ethical Violation Assessment And Risk Analysis Framework On Consumer-Held Values, Nada Ahmad Madkour

Master's Theses and Doctoral Dissertations

Background: The rapid growth of automated systems and artificial intelligence (AI), particularly, self-driving cars (SDCs), has attracted significant investments and can potentially contribute to humanity’s flourishing. However, before widespread adoption, it is important to address ethical violations such as bias in AI, highlighted by many real-world cases of bias in AI leading to unfair outcomes in tools like facial recognition, hiring software, and pedestrian detection. Bias in AI can lead to potentially fatal outcomes in SDCs, emphasizing the need for a thorough examination of bias in SDCs.

Purpose: To enhance AI ethics by providing tools to support transparency and value- …

Development Of An Executive Functioning Intervention To Improve Asthma Self-Management In Black Adolescents And Young Adults: Preliminary Feedback And Future Considerations, Kelsey L. Jong

Master's Theses and Doctoral Dissertations

n the United States, asthma is the most common chronic medical condition in youth, and it disproportionately affects Black adolescents. Numerous studies document poor asthma self-management for adolescents and young adults (AYAs), which compromises treatment effectiveness and drives up healthcare costs. However, it remains unclear how to increase health-promoting behaviors and reduce health disparities between Black AYAs and other races who experience better asthma-related outcomes. Interventions have been developed to improve adolescent self-management, yet few comprehensively address the psychological, cognitive, and contextual components that may interfere with an AYA's engagement in health behaviors, and few have developed interventions utilizing AYA …

Survivor Guilt And Posttraumatic Stress Among Young Adult Survivors Of Childhood Cancer, Alexandra Neenan

Master's Theses and Doctoral Dissertations

Childhood cancer survivors are at risk for a variety of adverse physical and mental health outcomes. Posttraumatic stress disorder (PTSD) occurs in a small, but notable, minority of childhood cancer survivors. Little is known about modifiable factors that may increase the risk of developing PTSD as a young adult survivor. One of the difficulties that has been minimally explored in this group is exposure to the deaths of other children with cancer, despite a 25% 15- year mortality rate among children who are diagnosed with cancer. The current study was among the first to explore potential impacts of this high …

“We Gon’ Be Alright”: How Resiliency & Africultural Coping Behaviors Factor Into African American College Students’ Intentions To Seek Mental Health Services, Taylor Garland

Master's Theses and Doctoral Dissertations

Background: African Americans, apprehension toward utilizing mental health services (MHS) has a long history in the United States. The low rates of utilizing MHS can result in detrimental health consequences, both mental and physical, despite there being a developing literature base on how evidence-based treatments are effective in therapy with African Americans.

Objective: There is expansive literature on several factors (e.g., stigma, cultural mistrust) that contribute to African Americans’ hesitancy concerning seeking MHS. The current study aimed to add to this literature base. Specifically, this study sought to acknowledge both African American college students’ choices to use alternative coping strategies …

Documenting Plant Biodiversity At The Emu-Owned Parsons Center For Arts And Sciences, Emily Edwards

Master's Theses and Doctoral Dissertations

We present the first vascular plant species checklist for the Eastern Michigan-University-owned property called the Parsons Center for Arts and Sciences. A voucher for each plant species has been deposited in the Eastern Michigan College herbarium and collection data is digitized in the Consortium of Midwest Herbaria. A minimum of three images per species are also available on iNaturalist . The Consortium and iNaturalist databases are publicly available and provide georeferenced locations for each plant. One hundred seventy-one plant species (in 137 genera and 61 families) were documented and identified, representing about 15% of plant species and 41% of families …

Evaluation Of Resurgence Following Differential Reinforcement Of Alternative Behavior With And Without Extinction In A Human-Operant Model, Skylar Dewitt

Master's Theses and Doctoral Dissertations

Differential reinforcement of alternative behavior (DRA) plus extinction for problem behavior is an evidence-based intervention for individuals diagnosed with autism. However, researchers have recently begun investigating DRA without extinction, given this treatment component may be unsafe or impractical to implement in practice. Although preliminary research has indicated DRA without extinction as an effective intervention alternative, little is known about the long-term implications of this intervention, especially as it relates to resurgence. This study investigated resurgence following DRA with and without extinction using a three-phase resurgence assessment in a human-operant arrangement across 60 college-aged participants. Several study iterations were required to …

Arousal Patterns, Fungal Loads, And Wing Damage In A Surviving Population Of Little Brown Bats (Myotis Lucifugus), Brooke A. Daly

Master's Theses and Doctoral Dissertations

Little brown bats (Myotis lucifugus) at Tippy Dam in Michigan have shown resilience to white-nose syndrome (WNS), which is caused by the fungus Pseudogymnoascus destructans. This study evaluated the impact of environment (temperature and moisture), pathogen virulence, and host susceptibility on survival. Host response was assessed using temperature-sensitive radio transmitters (n = 37) and ultraviolet photography (n = 57), while fungal load (n = 56) was evaluated through quantitative polymerase chain reaction (qPCR). High autumn temperatures (>10°C) favored growth of the fungus, while mid-hibernation temperature (3.2°C) was unfavorable. The mean torpor bout length (TBL) …

Automatic Modeling Of Cyber Intrusions Using The Diamond Model Utilizing Security Logs And Events, Mahmoud Al-Maani

Master's Theses and Doctoral Dissertations

Current intrusion analysis models suffer from unreliability and inaccuracy due to their reliance on outdated and inadequate data sources. Numerous models focus on a particular type of data, leading to potential modeling faults in intrusion analysis models' recommendations. The objective of this thesis is to build a modernized model by integrating the diamond model with security information and event management systems. This thesis presents a detailed cyber intrusion analysis model; in which Elasticsearch is being used to collect and analyze logs about cyber attacks and extract major indicators of compromise then finally map them to the diamond model. The results …

Behavioral Ecology Of The Colorado Brown Tarantula (Aphonopelma Hentzi): Activities Displayed Around The Burrow Through Juvenile Group Dispersal, Bradley Allendorfer

Master's Theses and Doctoral Dissertations

The life history strategy of the Colorado brown tarantula (Aphonopelma hentzi) typically includes males spatially scattering in search for a female mate in the fall, followed by female attendance of fertilized eggs the following summer. Here, I highlighted aspects associated with this female parental care. Specifically, I compared the activities of maternal (egg-attending) tarantulas to their non-maternal (not egg-attending) counterparts, as this may be a costly time for these egg-attending individuals. I concluded that maternal individuals tended to show reduced activity at the burrow entrance, however; these, results were significant in only one comparison. After weeks of this parental care, …