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2024

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Advantages And Disadvantages Of Technology In The Mathematics Classroom, Francena D. Gargaro Dec 2024

Advantages And Disadvantages Of Technology In The Mathematics Classroom, Francena D. Gargaro

Transformations

The integration of technology into teaching pedagogy, particularly in mathematics instruction, has been a subject of significant. This paper examines the impact of utilizing technology for mathematics education. It reviews multiple categories of technological tools available for classroom use, including hardware, software, and online resources, and discusses their potential benefits and drawbacks. Positive aspects of technology integration include personalized learning experiences, increased engagement and collaboration, and enhanced visualization and conceptual understanding. However, challenges such as dependency on technology, loss of conceptual understanding, distraction, and the widening achievement gap due to inequity are also addressed. The paper explores the role of …


Full Issue Dec 2024

Full Issue

Transformations

Full Issue


December 10, 2024 Ereporter, University Of Alabama At Birmingham Dec 2024

December 10, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


High Sacral Slope, Lumbar Lordosis, And Sacral Slope-To-Pelvic Incidence Ratio Are Associated With New Bone Formation In Ankylosing Spondylitis, Aysun Aksoy, Cemal Gündoğmuş, Mehmet Kesi̇mer, Kemal Nas, İkram Duman, Gazanfer Eki̇nci̇, Murat Bezer, Pami̇r Atagündüz Dec 2024

High Sacral Slope, Lumbar Lordosis, And Sacral Slope-To-Pelvic Incidence Ratio Are Associated With New Bone Formation In Ankylosing Spondylitis, Aysun Aksoy, Cemal Gündoğmuş, Mehmet Kesi̇mer, Kemal Nas, İkram Duman, Gazanfer Eki̇nci̇, Murat Bezer, Pami̇r Atagündüz

Turkish Journal of Medical Sciences

Background/aim: Syndesmophyte formation appears to be site specific in Ankylosing spondylitis(AS),and new bone formation seems to occur in regions of micro-trauma that are prone to tensile forces.Pelvic and spinal parameters are unique for individuals. Pelvic tilt and sacral slope are important anatomical features that compensate in harmony in keeping the sagittal balance. After puberty, the sacral slope shapes the lumbar lordosis, whereas the pelvic incidence is set to an individual constant. This study aims to analyze the properties of pelvic parameters in AS patients with and without syndesmophyte formation in the spine after 15years of disease duration.Materials and methods:Whole spine …


Comparison Of Rigid And Elastic Registration Methods In Software-Based Targeted Prostate Biopsy: A Multi-Center Cohort Study, Serhat Çeti̇n, Serdar Çeli̇k, Murat Koparal, Güven Aslan, Sertaç Yazici, Bahadir Şahi̇n, Si̇nan Sözen, Levent Türkeri̇ Dec 2024

Comparison Of Rigid And Elastic Registration Methods In Software-Based Targeted Prostate Biopsy: A Multi-Center Cohort Study, Serhat Çeti̇n, Serdar Çeli̇k, Murat Koparal, Güven Aslan, Sertaç Yazici, Bahadir Şahi̇n, Si̇nan Sözen, Levent Türkeri̇

Turkish Journal of Medical Sciences

Background/Aim: This study aims to compare the success rates of rigid registration (RR) and elastic registration (ER)systems in diagnosing all cancers and clinically significant prostate cancer (csPC) in software-based targeted prostate biopsies (TPBs) by performing matching analysis.Materials and Methods: The data of 2,061 patients from six centers where software-based TPB was performed were used. All cancer and csPC detection rates of the RR and ER systems were compared following Mahalanobis distance matching within the propensity score caliper method. Logistic regression analysis was applied to identify factors predicting clinically insignificant prostate cancer (ciPC) and csPC diagnoses. Additionally, the International Society of …


Diverse Possibilities Of Shakespeare: Teaching Twelfth Night Through A Queer Lens, Julia Ritzler Dec 2024

Diverse Possibilities Of Shakespeare: Teaching Twelfth Night Through A Queer Lens, Julia Ritzler

Honors Projects

This project seeks to understand the ways in which Queer Theory can be applied to secondary language arts education to enhance students' understanding of identity and gender in literature. For the purposes of this project, Shakespeare’s Twelfth Night is being used as a case study text. This project includes a thorough analysis of Twelfth Night through a queer lens, a literature review of Queer Theory and educational pedagogy, a block plan and related instructional and assessment materials, a rationale for the block plan, and project limitations and implications for future research. By analyzing scholarly texts and applying the theories within …


Exploring The Linkages Between Social Impact Grantmaking & Social Innovation: Insights For Grantmaking Practices, Jodi Lockhart Dec 2024

Exploring The Linkages Between Social Impact Grantmaking & Social Innovation: Insights For Grantmaking Practices, Jodi Lockhart

Masters Projects

The discussion and search for more advanced societal wellness and public health is centuries old, yet data suggests that public health and social care systems continue to struggle. In pursuit of mitigating this broad array of challenges, both government and private philanthropic funders have prolifically used grantmaking as a funding mechanism. Within this quest for positive social impact, many funders have expressed interest in the emerging field of social innovation. This study seeks to examine the use of social innovation in the strategic grantmaking practices of funders in Colorado, exploring how these organizations are integrating social innovation into their funding …


Evaluation Of The Update On Screening For Retinopathy Of Prematurity In A Tertiary Care Center In Türkiye With Retrospective Cohort, Emi̇ne Kaya Güner, Duygu İnci̇ Bozbiyik Dec 2024

Evaluation Of The Update On Screening For Retinopathy Of Prematurity In A Tertiary Care Center In Türkiye With Retrospective Cohort, Emi̇ne Kaya Güner, Duygu İnci̇ Bozbiyik

Turkish Journal of Medical Sciences

Background/aim: In Turkey, recommendations for screening for retinopathy of prematurity (ROP) have been updated in 2021. Herein, we aimed to present detailed data on the infants included in the screening according to the new criteria and evaluate whether these changes benefit in detecting severe ROP.Materials and Methods: Our hospital's medical records of babies screened for ROP between July 2019 - July 2021 and August 2021 - August 2023 were retrospectively examined. Gestational age (GA), birth weight (BW), gender of the babies, whether there was a multiple pregnancy, ROP examination results, the most advanced ROP level and time, and ROP treatment …


Evaluation Of The Efficacy Of Transfer Energy Capacitive And Resistive Therapy In Patients With Knee Osteoarthritis, Özge Tezen, Emi̇ne Esra Bi̇li̇r, Öznur Uzun, Duygu Yaniktaş, Başak Şentürk, Evren Yaşar Dec 2024

Evaluation Of The Efficacy Of Transfer Energy Capacitive And Resistive Therapy In Patients With Knee Osteoarthritis, Özge Tezen, Emi̇ne Esra Bi̇li̇r, Öznur Uzun, Duygu Yaniktaş, Başak Şentürk, Evren Yaşar

Turkish Journal of Medical Sciences

Background/aim: The aim of present study was to investigate the treatment efficacy of transfer energy capacitive and resistive (TECAR) therapy, a modern application that has been increasingly used in recent years, compared to conventional physical therapy (CPT) applications in the treatment of knee osteoarthritis, according to the evaluation of clinical findings of patients.Materials and methods: A total of 54 patients, aged between 40 and 75 years, were randomly divided into two groups. Both groups received CPT. Group 2 received TECAR therapy in addition to CPT, applied three times a week for two weeks, for a total of 6 sessions. All …


Civil Rights Clinic Files Brief In Solitary Confinement Lawsuit Against Mayor Eric Adams, Cardozo Civil Rights Clinic Dec 2024

Civil Rights Clinic Files Brief In Solitary Confinement Lawsuit Against Mayor Eric Adams, Cardozo Civil Rights Clinic

Cardozo News 2024

The New York City Council and Public Advocate Jumaane Williams filed a joint lawsuit to invalidate New York City Mayor Eric Adams’ emergency executive orders that suspend parts of Local Law 42, which bans solitary confinement in city jails. Cardozo School of Law’s Civil Rights Clinic represents the #HALTsolitary Campaign & Jails Action Coalition. Clinic students Elisa Davila ’26 and Ciara Lavin ’26, along with Clinic Director Professor Betsy Ginsberg, are filing an amicus brief on their behalf. The organizations joined public defenders’ offices and the New York Civil Liberties Union as amici to the case.


Trustee's Objection To Disclosure Statement Dec 2024

Trustee's Objection To Disclosure Statement

Catholic Dioceses in Bankruptcy

No abstract provided.


The Effect Of Applied Mental Health Courses On College Student Anxiety And Perfectionism, Nathan Thomas Rhees Dec 2024

The Effect Of Applied Mental Health Courses On College Student Anxiety And Perfectionism, Nathan Thomas Rhees

Theses and Dissertations

University students face a variety of mental health challenges, including increasingly high rates of anxiety. As demand for college counseling services among student populations rises, universities have an increasing need for effective and resource-efficient methods of intervention that support student mental health on their campuses. One area in need of research is that of using university classes themselves as a form of preventive intervention. If effective, this kind of preventive measure might be a particularly attractive method of reducing incidence of mental illness on campus and decreasing demand on university therapy resources. This study involves students at a private university …


Securing Legacy Multivalue Pick Systems Modernized By Restful Web Service Apis, Jacob S. Lee Dec 2024

Securing Legacy Multivalue Pick Systems Modernized By Restful Web Service Apis, Jacob S. Lee

Theses and Dissertations

With more applications accessible on the Web, organizations with mission-critical legacy systems have had to find a way to stay relevant and competitive by modernizing with RESTful APIs. REST architecture, serving as a guideline rather than a strict protocol, offers significant advantages in terms of scalability, flexibility, and independence; however, its widespread adoption has also led to notable security vulnerabilities and weaknesses. Additionally, there is not one all-encompassing security testing methodology to follow when testing RESTful APIs. For this reason, a new security testing methodology was developed for legacy MultiValue Pick systems that implement the REST API component, MVConnect. The …


Lifetime Stressor Exposure Is Related To Suicidality In Autistic Adults: A Multinational Study, Rachel L. Moseley, Darren Hedley, Julie M. Gamble-Turner, Mirko Uljarević, Simon M. Bury, Grant Shields, Julian N. Trollor, Mark A. Stokes, George M. Slavich Dec 2024

Lifetime Stressor Exposure Is Related To Suicidality In Autistic Adults: A Multinational Study, Rachel L. Moseley, Darren Hedley, Julie M. Gamble-Turner, Mirko Uljarević, Simon M. Bury, Grant Shields, Julian N. Trollor, Mark A. Stokes, George M. Slavich

Psychological Science Faculty Publications and Presentations

Despite very high rates of suicidal thoughts and behaviors (STB) in autistic adults, the key psychosocial drivers of this phenomenon remain unknown. To investigate, we examined how lifetime stressor exposure and severity, which have been found to predict STB in non-autistic populations, related to STB in a multinational dataset of 226 autistic adults from the United Kingdom and Australia (67% female; Mage = 41.8, SD = 13.6, range = 19–73 years old). Results revealed that autistic men and women differ with respect to the count, severity, and type of stressors they experienced over the life course. Whereas autistic men …


Aud175 Project 3: Acoustics, Sae University College Dec 2024

Aud175 Project 3: Acoustics, Sae University College

Exemplars

Acoustics Analysis:

1: RT60 Calculations: Use an RT60 calculator to predict the reverb time of a real room. Measure the actual time and compare the results.

2. Acoustic Treatment. Take RT60 measurements in a space before and after basic acoustic treatment and explain how the treatment is affecting the acoustics.

3. Room Modes Predict the positions of standing waves and room modes in a room and test your predictions with measurements.


Aud215 Project 1: 24t3 Example 1, Sae University College Dec 2024

Aud215 Project 1: 24t3 Example 1, Sae University College

Exemplars

Documentation for a Native Instruments Kontakt Instrument - with marketing material and summary of recording and coding process - with links to physical submission.


Ai-Driven Anomaly Detection In Cybersecurity, Mohamed Almansoori Dec 2024

Ai-Driven Anomaly Detection In Cybersecurity, Mohamed Almansoori

Theses

India has witnessed a huge level of digitization in the last two decades which has greatly impacted its economy and society. But the increasing use of technology has also intensified the number and level of threats to cyberspace in the country. Signature-based detection systems that have dominated the cybersecurity field for years have not been up to the challenge of modern attackers who use more complex and diverse attack methods. These challenges are well understood and this research focuses on improving the cybersecurity anomaly detection in India during the period between 2003 and 2022 using advanced AI and machine learning. …


Chest Disease Classification Using Transfer Learning, Adarsh Neema Dec 2024

Chest Disease Classification Using Transfer Learning, Adarsh Neema

Theses

In the domain of medical diagnostics, the precise classification of chest diseases has become very important, particularly during the occurrence of the COVID-19 pandemic. This project proposes an innovative approach to automate the classification process through the usage of deep learning technique, and more specifically making use of convolutional neural networks (CNNs) and transfer learning, with a prime focus on the RESNET50 architecture. The primary objective is to develop a model which is intelligent enough to detect various chest conditions, including COVID- 19, viral pneumonia, bacterial pneumonia, and normal cases. Utilizing the rigorously pre-trained knowledge encoded within RESNET50, trained on …


Precision Reclamation For Improving Mine-Land Reclamation Using Plant-Soil Chemical Analysis And Geospatial Technology, Haley Moon Dec 2024

Precision Reclamation For Improving Mine-Land Reclamation Using Plant-Soil Chemical Analysis And Geospatial Technology, Haley Moon

Theses and Dissertations

The objective of this research was to assess plant-soil relationships and evaluate the use of multispectral drone imagery in predicting revegetation potential and soil properties at mine-land waste rock dumps. Field sampling of soils and vegetation was conducted, followed by Bayesian statistical significance tests and linear discriminant analysis (LDA) to determine key soil variables influencing plant communities. Results indicated that pH and electrical conductivity (ECe) were significant factors in the LDA and identified several plant communities that were associated with similar soil types. In parallel, regression analyses were employed to correlate multispectral drone imagery with soil characteristics and plant cover. …


The Assessment Of Liquefaction Surface Ejecta Predictions On A New Large Dataset From The 2012 Emilia Romagna, Italy Earthquakes, Holten T. Flinders Dec 2024

The Assessment Of Liquefaction Surface Ejecta Predictions On A New Large Dataset From The 2012 Emilia Romagna, Italy Earthquakes, Holten T. Flinders

Theses and Dissertations

The presence of a non-liquefied crust overlying a liquefied layer has been found to have a significant effect on sand ejecta and surficial liquefaction damage, as observed by Ishihara (1985). Following the 2010-2011 Canterbury seismic sequence in New Zealand, almost no foundation deformation occurred in areas with liquefaction susceptible soils overlain by at least a 3 m-thick crust [3]. In contrast, the 2012 Emilia-Romagna earthquake in Italy provided surface evidence of liquefaction despite 6- to 10 m-thick crusts. Several researchers have proposed liquefaction prediction models [e.g. LPI [6], Ishihara Curves [8], LSN [9], LPIISH [10] and the methods proposed by …


The Long Shadow Of Infection: The Long-Term Implications Of Herpes Simplex Virus And M. Tuberculosis Infection, Lydia Howell Dec 2024

The Long Shadow Of Infection: The Long-Term Implications Of Herpes Simplex Virus And M. Tuberculosis Infection, Lydia Howell

Theses and Dissertations

Infectious diseases and autoimmune diseases, such as multiple sclerosis (MS) and type 1 diabetes (T1D), have traditionally been seen as distinct, with separate etiologies and courses of disease. Recent research has shown that infection and autoimmune disease are more closely woven together than previously thought; certain pathogens like Epstein-Barr virus and M. tuberculosis have been shown to cause long-term disruption to the immune system, for example (Bordignon et al 2011, #1) (Zhang et al 2023, #2) (Bjornevik et al 2023, #3). Conversely, a distinct pattern has emerged in developed countries where as rates of infection fall, rates of autoimmune disease …


The Relationships Between Binge-Watching Behavior, Content Familiarity, Depression, And Anxiety, Emma Miller Dec 2024

The Relationships Between Binge-Watching Behavior, Content Familiarity, Depression, And Anxiety, Emma Miller

Master's Theses & Other Graduate Student Works

This December 2024 Master of Science in Psychology thesis at Lipscomb University analyzes how binge-watching has become a dominant media consumption behavior, yet its psychological impacts remain understudied. This thesis examines the relationships between binge-watching behavior, content familiarity, depression, and anxiety, with a focus on whether familiarity moderates mental health outcomes. A sample of 94 participants completed surveys measuring binge-watching habits, content familiarity, and mental health indicators using the CES-D and SCAARED scales. Results from multiple regression analyses indicated that age, content familiarity, and viewing context significantly predicted depression, while only age predicted anxiety. Notably, participants who binge-watched familiar content …


The Oak Springs Biker, Sarah Rogers Dec 2024

The Oak Springs Biker, Sarah Rogers

Master's Projects

More often than not in teen or young adult-oriented media, the characters and circumstances are ordinarily categorized into archetypes to replicate real-life conditions. Said archetypes in turn periodically portray fabricated or discrediting representations of certain individuals and characteristics, which is what prompted me to revert these representations (specifically those of adolescent characters and contexts) through an artistic, potent deliverable: a screenplay. My screenplay, The Oak Springs Biker, explores numerous adolescents' narratives within a reputable, correctional boarding school, and how these adolescents' lives intersect amid their personal growth and evolvement journeys. Procedurally, I examined six films and their respective screenplays, …


Assessment Of Bite Force And Masseter And Temporal Muscles Thickness In Adult Women Undergoing Buccal Fat Pad Removal Surgery–Bichectomy, Thamyres Branco, Marcelo Palinkas, Alice Helena De Lima Santos Cardoso, Nicole Barbosa Bettiol, Paulo Batista De Vasconcelos, Gabriella Simi Gariba Silva, Jéssica Brandani Chiaratto, Patricia Santos De Lima, Samuel Porfírio Xavier, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo Dec 2024

Assessment Of Bite Force And Masseter And Temporal Muscles Thickness In Adult Women Undergoing Buccal Fat Pad Removal Surgery–Bichectomy, Thamyres Branco, Marcelo Palinkas, Alice Helena De Lima Santos Cardoso, Nicole Barbosa Bettiol, Paulo Batista De Vasconcelos, Gabriella Simi Gariba Silva, Jéssica Brandani Chiaratto, Patricia Santos De Lima, Samuel Porfírio Xavier, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo

Journal of Dentistry Indonesia

Objective: Bichectomy, a surgical procedure that removes the buccal fat pad, can affect masticatory function, including bite force and muscle thickness, in adult women. This study aimed to assess the bite force as well as masseter and temporal muscle thicknesses before and 30 and 60 days after bichectomy in adult women. Methods: This longitudinal study included a sample of 20 adult women (mean age 31.1 ± 9.84 years), with normal occlusion and no history of temporomandibular disorder. The molar bite force was assessed using a dynamometer, while the masseter and temporal muscle thicknesses at rest and during dental …


The Accuracy Of Detection And Diagnosis Of Oral Lesions By Clinical Dental Students, Carinna Tirtania, Dewi Priandini, Najla Nadiah, Indrayadi Gunardi, Hrishikesh Sathyamoorthy Dec 2024

The Accuracy Of Detection And Diagnosis Of Oral Lesions By Clinical Dental Students, Carinna Tirtania, Dewi Priandini, Najla Nadiah, Indrayadi Gunardi, Hrishikesh Sathyamoorthy

Journal of Dentistry Indonesia

Objective: To determine the accuracy of diagnosing oral lesions through clinical photos taken by clinical dental students (CDS). Methods: The observational analytic study was conducted on 100 CDS to evaluate 140 clinical photos of oral lesions. The gold standard was evaluated by three oral medicine specialists. Data analysis will be performed using accuracy and kappa tests. Results: The accuracy rate of lesion detection in CDS is high (88.55%) with substantial agreement (κ = 0.66). However, the accuracy rate of diagnosis is low (38.21%) with no agreement (κ = -0.30). Participation in the clinical Oral Medicine module positively …


Histomorphometric Assessment Of Vibrational Forces On The Extended Midpalatal Suture, Aylin Pasaoglu Bozkurt, Özge Özdal Zincir, Asli Emincik Dec 2024

Histomorphometric Assessment Of Vibrational Forces On The Extended Midpalatal Suture, Aylin Pasaoglu Bozkurt, Özge Özdal Zincir, Asli Emincik

Journal of Dentistry Indonesia

Objective: This study determined the effects of vibrational forces on bone formation in the retention period of an expanded mid-palatal, histomorphometric suture in a rat model. Methods: Twenty-four 7–8- to 8-week-old male Wistar rats weighing 190.25 ± 15.35 g were separated into groups: only expansion (G1), expansion and 30 Hz vibration application (G2), and expansion and 111 Hz vibration application (G3). After 5 days of expansion, there were 12 days of retention. All animals were sacrificed, and their premaxilla were dissected. A histological examination evaluated the number of osteoblasts, osteoclasts, and capillaries, the amount of mineralized area, and …


Knowledge, Attitude, Oral Hygiene Practice And Self-Perception On Periodontal Health Among Older Adult Population In Malaysia, Annabel Shanta Edwin Thomas, Haslina Taib, Zurairah Berahim, Siti Lailatul Akmar Zainuddin, Munirah Mohd Adnan Dec 2024

Knowledge, Attitude, Oral Hygiene Practice And Self-Perception On Periodontal Health Among Older Adult Population In Malaysia, Annabel Shanta Edwin Thomas, Haslina Taib, Zurairah Berahim, Siti Lailatul Akmar Zainuddin, Munirah Mohd Adnan

Journal of Dentistry Indonesia

Objective: This study aimed to assess the knowledge, attitude, oral hygiene practice, and self-perception of periodontal health among the older adult population in Malaysia and its association with demographic factors. Methods: An online questionnaire assessing their knowledge, attitude, oral hygiene practices, and self-perception of periodontal disease was distributed to adults aged 50 years and above. Results: 397 respondents participated. The mean knowledge score was 1.36 (SD 0.92), significantly associated with gender, ethnicity, education, and occupation. About 63% of respondents know that poor oral hygiene is related to general health and is significantly associated with ethnicity (p = …


Effectiveness Of Mucoadhesive Patch Clitoria Ternatea Extract In Wound Healing Process After Tooth Extraction In Sprague Dawley Rats, Rahma Ika Amalia, Wahyu Prastiya, Nur Meirawati, Helmi Hirawan, Dwi Nur Indah Sari Dec 2024

Effectiveness Of Mucoadhesive Patch Clitoria Ternatea Extract In Wound Healing Process After Tooth Extraction In Sprague Dawley Rats, Rahma Ika Amalia, Wahyu Prastiya, Nur Meirawati, Helmi Hirawan, Dwi Nur Indah Sari

Journal of Dentistry Indonesia

Objective: This study aims to evaluate the effectiveness of mucoadhesive patch clitoria ternatea extract for wound healing post-tooth extraction. Methods: The research was carried out experimentally in a laboratory. 30 Sprague Dawley rats were selected and randomly divided into mucoadhesive patch clitoria ternatea (MPCT) 5%, 10%, 15%, positive and negative control groups. The upper incisors of rats were extracted and treated once a day for 7 and 14 days. Wound healing was observed based on histological observation (fibroblasts, collagen density, and epithelial thickness). Data was analyzed statistically. Results: MPCT 15% applied for 14 days showed the highest …


Effective Strategies To Improve Job Satisfaction And Reduce Property Manager Turnover, Rita Khan Dec 2024

Effective Strategies To Improve Job Satisfaction And Reduce Property Manager Turnover, Rita Khan

Walden Dissertations and Doctoral Studies

High turnover rates among property managers disrupt service quality, increase operational costs, and diminish tenant satisfaction. Despite these negative impacts, there is limited research on effective retention strategies within the industry. Grounded in Herzberg’s two-factor theory, the purpose of this qualitative pragmatic inquiry was to explore strategies that property management leaders use to improve job satisfaction and reduce turnover. Six experienced property management leaders from the Midwestern United States who have successfully implemented retention strategies participated in this study. Data were collected through semistructured interviews and analyzed using Braun and Clark’s six-phase thematic analysis, revealing four key themes: work-life balance …


An Empirical Model Of Carbon-Ion Relative Biological Effectiveness Based On The Linear Correlation Between Radiosensitivity To Photons And Carbon Ions, David B Flint, Scott J Bright, Conor Mcfadden, Teruaki Konishi, David K J Martinus, Mandira Manandhar, Mariam Ben Kacem, Lawrence Bronk, Gabriel O Sawakuchi Dec 2024

An Empirical Model Of Carbon-Ion Relative Biological Effectiveness Based On The Linear Correlation Between Radiosensitivity To Photons And Carbon Ions, David B Flint, Scott J Bright, Conor Mcfadden, Teruaki Konishi, David K J Martinus, Mandira Manandhar, Mariam Ben Kacem, Lawrence Bronk, Gabriel O Sawakuchi

Faculty, Staff and Student Publications

Objective.To develop an empirical model to predict carbon ion (C-ion) relative biological effectiveness (RBE).Approach.We used published cell survival data comprising 360 cell line/energy combinations to characterize the linear energy transfer (LET) dependence of cell radiosensitivity parameters describing the dose required to achieve a given survival level, e.g. 5% (D5%), which are linearly correlated between photon and C-ion radiations. Based on the LET response of the metrics D5%and D37%, we constructed a model containing four free parameters that predicts cells' linear quadratic model (LQM) survival curve parameters for C-ions,αCandβC, from the reference LQM parameters …