Digital Commons Network^™

Utility Of Immobilized Metal Salens As Electrocatalysts: Fuel Cells And Organic Electrosynthesis, Zachary A. Nguyen, Shelley D. Minteer

Chemistry Faculty Research & Creative Works

There have been significant advancements in the electrosynthesis of fuels and organic molecules, making it an increasingly sustainable and cost-effective alternative to traditional chemical redox reagents. Early versions of these systems faced challenges in chemo selectivity due to high applied overpotentials, which have been mitigated with the introduction of molecular electrocatalysts, like metal salens (MSalens). These MSalens reduce the required overpotentials, increase turnover numbers (TON), and have simple modularity within their ligand structure allowing for tunable selectivity. While these MSalen electrocatalysts are typically used homogeneously for engineering simplicity, downstream separations are often costly and time-consuming. Immobilization of MSalens addresses these …

Development Of A Ripk1 Degrader To Enhance Antitumor Immunity, Xin Yu, Dong Lu, Xiaoli Qi, Rishi Ram Paudel, Hanfeng Lin, Bryan L Holloman, Feng Jin, Longyong Xu, Lang Ding, Weiyi Peng, Meng C Wang, Xi Chen, Jin Wang

Faculty, Staff and Students Publications

The scaffolding function of receptor interacting protein kinase 1 (RIPK1) confers intrinsic and extrinsic resistance to immune checkpoint blockades (ICBs) and emerges as a promising target for improving cancer immunotherapies. To address the challenge posed by a poorly defined binding pocket within the intermediate domain of RIPK1, here we harness proteolysis targeting chimera (PROTAC) technology to develop a RIPK1 degrader, LD4172. LD4172 exhibits potent and selective RIPK1 degradation both in vitro and in vivo. Degradation of RIPK1 by LD4172 triggers immunogenic cell death, enhances tumor-infiltrating lymphocyte responses, and sensitizes tumors to anti-PD1 therapy in female C57BL/6J mice. This work reports …

Ndls Communicator: Week Of 12.16.24, Notre Dame Law School

NDLS Communicator

The Latest News

• ND Law Global Visiting Professors Bring International Expertise to the Classroom and Notre Dame Community
• Notre Dame Law School's Religious Liberty Clinic defends religious freedom through asylum
• Notre Dame Religious Liberty Clinic files amicus brief to support Indigenous efforts to protect sacred site in Texas
• Dean Cole offered a prayer for students as they began final exams.

Faculty News and Briefs

• On November 18, Jeff Pojanowski spoke at an event by the American Enterprise Institute and Catholic University on Professor Stephen Smith's book, Law's Quandary.
• Carter Snead's book, What it Means to be Human, was included in …

Re: Comment Letter For The Draft Final Butte Reduction Works (Brw) Smelter Area Mine Waste Remediation And Contaminated Groundwater Hydraulic Control Site Quality Assurance Project Plan (Qapp) For Microbial Analysis And Biotreatability Study (Dated October 10, 2024), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

A Contemporary Examination Of Racial Intraminority Relations: Attitudes, Motivations, And Barriers To Participation In Collective Action, Jaboa Shawntaé Lake

Dissertations and Theses

Social movements globally and within the U.S. are gaining widespread acknowledgment as many individuals become more aware of systems of disadvantage and oppression, gain a better understanding of their root causes, and engage in collective ways to approach social change. Social science research on engagement with collective action has started to go beyond looking only at majority-minority relations (such as between White and Black people) to examine solidarity and coalition building between minoritized groups. This dissertation expands the literature both on collective action and intraminority intergroup relations through three manuscripts. Chapter II explores various social attitudes (e.g., awareness of privilege …

Portraits Of Agency And Power: Exploring Andean Women In Guamán Poma's Chronicle, Ruby Sygar

University Honors Theses

This study explores the depictions of women in Felipe Guamán Poma de Ayala’s chronicle titled, El primer nueva crónica y buen gobierno. By concentrating on six distinct portraits within this manuscript, the findings intend to reveal the themes, differences, and symbolic meanings that characterize and differentiate these representations. The analysis delves into how these portrayals provide insights into the roles, status, and societal perceptions of women in Inca society during the colonial period. The situation of these depictions within the general context of gender and colonialism in Andean society aims to showcase how nobleman Guamán Poma’s work critiques and …

The Boris Experience: Evaluating Omnichannel Returns And Repurchase Intention, Jianliang Hao, Robert G. Richey Jr., Tyler R. Morgan, Ian M. Slazinik

Faculty Publications

Researchers have examined the influence of the factors on reducing return rates in retailing over the years. However, the returns experience is often an overlooked way to drive customer engagement and repeat sales in the now ubiquitous omnichannel setting. The focus on returns prevention in existing research overshadows management’s need to understand better the comprehensive mechanics linking the customer in-store return experience with their repurchase actions. Recognizing the need to bridge different stages of the returns management process, this research aims to explore the facilitators and barriers of in-store return activities.

Improving Health And Well-Being Through Shared Family Meals, Halle Larson, Savannah Daines, Stacy Bevan, Palak Gupta, Mateja R. Savoie-Roskos

All Current Publications

Shared family meals provide numerous benefits for children, adolescents, and parents, including improved diet quality, healthier weight, better academic performance, stronger family bonds, and enhanced mental health. Regular family meals help children develop healthier eating habits, reduce risky behaviors, and foster communication skills. Despite challenges such as busy schedules and differing dietary preferences, families can overcome obstacles by starting small, keeping meals simple, involving everyone in meal prep, and minimizing distractions like screens. Creating a positive, flexible mealtime routine can help integrate these valuable moments into family life.

Orosipon Kan Bikolnon: Interrupting The Nation, Raniela Barbaza

Kritika Kultura

If narration points to notions of fixity in terms of the position of the narrator and the subsequent structuring of events, orosipon, a Bikolnon word for “story,” suggests a refusal to fixity both in terms of the location of the narrator and the structure itself of the story: the story never stops being formed as it passes through multiple speakers. Orosipon, coming from the root word osip which approximates the verb “tell,” points to more than one person involved in an act of telling, which makes the act of telling proper to no one in particular: indeed, it is improper …

Philippine Theater In Confinement: Breaking Out Of Martial Law, Bienvenido Lumbera

Kritika Kultura

The declaration of Martial Law during the Marcos administration brought about a period of censorship and a complete rejection of any form of protest against the established figures of authority. Activists then looked for other forms of communication through which they could channel their dissent and rally more people towards the cause. It was during this period that Philippine theater was taken out of the stage and into the streets, when the “art” of the “elite” was brought down to the masses. These efforts also shifted the language of Philippine theater from American English to Pilipino, marking the beginning of …

Socialist Shenanigans And Emerald Epiphanies: The Case Of Margaretta D'Arcy And John Arden, Tim Prentki

Kritika Kultura

This essay explores the two meanings of “radical” – the popular one of “sharp-edged’”or “extreme” and the original one of “rooted within the culture” – in relation to selected works of D’Arcy and Arden: The Non-Stop Connolly Show (1975), Vandaleur’s Folly (1978) and The Little Gray Home in the West (1978). Within the space of contradiction between these meanings, the paper considers such issues as the political function of the outsider, the rival claims of reform and revolution, relationships between text and means of production and between forms and audience ownership. The perennial question of the battle between republicanism and …

Short Notations And Reflections On Pantayong Pananaw, Aaron Rom O. Moralina

Kritika Kultura

This paper answers the question “What is Pantayong Pananaw?” through the subject of its study, its methods, its mode of communicating knowledge, and how it has served as a conscious effort of counteracting Western historiographic discourse. It also discusses the limitations and pitfalls of Pantayong Pananaw as well as its possible directions and trajectories.

Paraphrasing Europe: Translation In Contemporary Filipino History, Portia L. Reyes, Ramon Guillermo

Kritika Kultura

This paper studies three annotated translations into Filipino that have been inspired by the controversial historiographical movement called Pantayong Pananaw (from us-for us perspective), which argued for the use of the national language in academic study: San Agustin’s 1720 letter (by Dedina Lapar), Canseco’s 1897 account of Cavite during the Philippine Revolution (by Rhommel Hernandez), and Marx and Engel’s 1848 Communist Manifesto (by Zeus Salazar). In seeking to understand the translational practices that assist in the production and institutionalization of knowledge today, we ask: what transpires in the Filipinization of an account? In which way is translation significant to indigenization …

The World, The Text, And S. P. Lopez, Rafael A. Acuña

Kritika Kultura

The paper studies Salvador P. Lopez’s position as a secular critic by analyzing his milieu during the Commonwealth period, criticism of his collection Literature and Society, and the content of essays from the same collection in light of the debate between “art for art’s sake” and proletarian literature. The theoretical framework used is Edward Said’s secular criticism.

Jose Garcia Villa: Vicissitudes Of Necolonial Art-Fetsishism And The "Beautiful Soul" Of The Filipino Exile, E. San Juan Jr.

Kritika Kultura

The publication of Jose Garcia-Villa’s Doveglion: Collected Poems by Penguin Books in 2008 is remarkable not because it reveals a renewed interest in Villa’s work (as Luis Francia claims in the introduction of the book) but because it presents the nostalgic posthumous return of the repressed. Francia, a Villa critic, fails to situate the poet in the context of the Philippines’ neocolonial status. Francia’s mapping of Villa’s trajectory as a poet is teleological; it elides those historical contexts that allowed US imperialist power to dominate the Philippine political economy in certain periods. Timothy Yu, a Chinese-American Stanford scholar, contends that …

Resisting Boundaries: An Interview With Suchen Christine Lim, Lawrence L. Ypil

Kritika Kultura

No abstract provided.

Ilocano Immigrant' Renegotiation Of Space In Gumil Hawaii Fiction (Circa 80s), Ma. Socorro Q. Perez

Kritika Kultura

Migration, transportation, overseas labor, globalization, etc., have spawned complex and overdetermined consequences—among them the unprecedented migration of Filipinos, particularly Ilocanos, to Hawaii. The Philippines’ colonial history and neo-colonial realities often figure in the Filipinos’ construction of their identity in Hawaii, resulting in their essentialization as unskilled, uneducated, and unassimilable plantation laborers. The decline of the plantation era, however, led to the reconstitution of the Ilocano labor force into the “new plantations” of the tourism industry’s hotel and restaurant sectors. The new set-up is nonetheless rooted in what E. San Juan calls the “integration of Filipinos into US society on the …

Killing Time: The Condition Of Exile In The Fiction Of Jose Y. Dalisay, Jr., Cyan Abad-Jugo

Kritika Kultura

The exilic condition extends not only to the Filipino who has chosen to study or live abroad, or is forced to leave the Philippines, but also the Filipino who, though he resides and works in his own country, feels himself in a state of rootless suspension brought about by the circumstances of history and colonization. In this light, all Filipinos—belonging to one or the other geographic, economic, tribal or social group—could be considered exiles, and this could be reflected in our literature. Dolores Feria states: “our literature has always been a consequence of exile.” A Filipino writer’s works could be …

Ang Mga Pinagdaanang Buhay Ng Ibong Adarna: Narrativity And Ideology In The Adarna's Corrido And Filmic Versions, Francisco Benitez

Kritika Kultura

Through a consideration of narrativity, the paper explores different structures of recognition in the corrido and 1941 filmic versions of the Ibong Adarna. The paper compares the chapbook’s context and narrative techniques with that of the film’s capacity to address an audience and creating subject-forms. It explores the applicability of James Siegel’s concept of the lingua franca’s communicative power to the Philippine situation, and suggests that different textual technologies contain different though overlapping grammars that affect their ideological functions.

Poems, Mary Kennan Herbert

Kritika Kultura

No abstract provided.

Scenes Of Translation: Responses To Responses, Vicente L. Rafael

Kritika Kultura

In his “Response to Responses,” Vicente Rafael thanks and answers the questions raised during the forum. To Gary Devilles’s comment of his “remaining silent” in the way translation can be “radicalized into an ethical technology or a strategic pedagogy,” Rafael offers the trope of revenge—a desire for justice, which results from the Spanish misrecognition of Filipino attempts at translation—and the language of secrecy and solidarity of the 1896 Revolution—which results from the failure of Castilian to become lingua franca—as political technics in themselves. To Ramon Guillermo’s comment of the book’s impoverished, restrictive, and imprecise notions of translation, Rafael reiterates and …

Commentary On The Promise Of The Foreign, Remmon E. Barbaza

Kritika Kultura

Guided by key Heideggerian insights, this review focuses on two points: 1) the relationship between what is foreign and what is one’s own; 2) language and history. The promise of the foreign belongs to the allure of the unknown, and the impulse to know the unknown belongs to the “de-distancing” character of the human—the tendency of human beings to bring things to nearness, thereby negating the distance that stands between them and the things they encounter in the world. Rafael has shown that the Filipinos were driven by the desire to bring what is foreign (in their case, Spain) near …

Response To The Promise Of The Foreign, Roland Tolentino

Kritika Kultura

In his “Response to The Promise of the Foreign,” Roland Tolentino generates a battery of provocative questions that seeks to resituate Rafael’s trope of “the foreign,” particularly in the field of Philippine Studies. Here, Tolentino asks nine questions that open up “the foreign” into zones of contacts with other contexts: the foreign in relation to the linguistic context of the period; its relationship with the vernacular, particularly in the case of the recodification of the baybayin; its involvement with act of writing and rewriting; its viability as a social project and its political efficacy; the foreign and its relation to …

A Book Review Of The Promise Of The Foreign, Ramon Guillermo

Kritika Kultura

Primarily taking issue with Rafael’s definition of translation as “that double process of appropriating and replacing what is foreign while keeping its foreignness in view,” this review attempts to show the unusually restrictive nature of this definition and proposes a more empirical approach to the study of translation and lexicalization.

A Book Review Of Vicente L. Rafael's The Promise Of The Foreign, Gary C. Devilles

Kritika Kultura

The book The Promise of the Foreign is without doubt well-written and contributes to our understanding of the fundamental assumptions informing nationalist discourse, as well as the contradictions and complex realities at work in Philippine society. However, the book is arguably silent on how such translation can also be radicalized into an ethical technology or strategic pedagogy such that the foreign within various socio-political sites of analysis like the natives, masses, the Chinese are not just regarded as contaminations between the Philippines and the outside but rather as ambiguities that create the conditions of possibility of the nation-state and its …

Writing Fiction: Imagination, History, And Voice In Singapore Fiction, Suchen Christine Lim

Kritika Kultura

No abstract provided.

Caveats On The Problem Of Understanding Peirce's Semiotics And Pragmatism, E. San Juan Jr.

Kritika Kultura

“Caveats” is San Juan’s response to “Addendum” in which he praises Stecconi’s focus on Peirce’s theory of knowledge rather than merely on his linguistic paradigm. San Juan, however, disagrees with Stecconi for “conflating the various pragmatisms into one lump.” San Juan prefers to regard Peirce as “a moderate realist” and reiterates the potential relevance of Pierce’s semiotics to the global war on terrorism and the Sri Lankan civil war.

The Case Of The Disappearing Filipino American Houseboy: Speculation On Double Indemnity And The United States Imperialism, Victor Bascara

Kritika Kultura

The creations of a new cultural formation, US imperialism, development, and globalization are traced in this article by the use of James M. Cain’s 1936 pulp novella-turned-film Double Indemnity. Representations of the Fil-Am houseboy, his disappearance and re-appearance in the texts, provide an impetus for discovering the cultural transitions from the colonial to the postcolonial periods.

Signs, Meaning, Interpretation: C. S. Peirce's Critique Of Deconstruction And Post-Structuralism, E. San Juan Jr.

Kritika Kultura

From the perspective of Peircian semiotics, this paper presents a prolegomenon of “a science of pragmaticist aesthetics.” Following the fundamental epistemological categories of C. S. Pierce, San Juan reads Michael’s Ondaatje’s Anil’s Ghost as unraveling the anatomy of terror in Sri Lanka. Such a reading, for San Juan, “elicit signs of whether we, and others in the collaborative enterprise, embody,” quoting Pierce, “an intelligence capable of learning by experience.”

En-Gendering Desire In Aida Santos's Lesbian Poetry, Danicar Mariano

Kritika Kultura

Lesbian feminist literary criticism seeks to deconstruct the essential categories of male and female and their “natural” link to the production of desire, enabling an insightful criticism that formalism and feminism alone cannot fully venture in. Thus, this lesbian feminist literary reading of Aida Santos’s poetry critiques heteropatriarchy in language, desire and gender by questioning the binary assumption operative in them. A binary logic defines women and men by what each are not, highlighting one sex over the other, and presenting them as in need each other. This patriarchal assumption intersects with compulsory heterosexuality to marginalize lesbian existence in the …