Digital Commons Network^™

Effect Of Soybean And Seaweed-Based Diets On Growth Performance, Feed Utilization, And Gut Microbiota Of Tilapia: A Systematic Review And Meta-Analysis, Leonildo Dos Anjo Viagem, Jean Nepomuscene Hakizimana, Cyrus Rumisha, Brunno Da Silva Cerozi, Gerald Misinzo

All Rsif Scholars' Publications

Tilapia, a significant aquaculture species globally, relies heavily on feed for its production. While numerous studies have investigated the impact of soybean and seaweed-based diets on tilapia, a comprehensive understanding remains elusive. This review aimed at evaluating and synthesizing the existing literature on these diets’ effects, focusing on growth performance, feed utilization, and gut microbiota. A systematic search of databases was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and a total of 57 studies were included in the qualitative analysis and 24 in the meta-analysis. The results indicated that soybean-based diets, at a 59.4% inclusion …

Insights On The Microbiology Of Ethiopian Fermented Milk Products: A Review, Tiruha Habte Karssa

All Rsif Scholars' Publications

Fermented milk products play a vital role in the diets of Ethiopians. They are produced from either spontaneous fermentation or back-slopping methods at the household level, in which lactic acid bacteria (LAB) and yeasts predominate. As a result, the processing steps are not standardized and overall safety is still of public health relevance. Therefore, quality and safety improvement, standardization of traditional manufacturing practices, and commercialization of products to a wider market are important. Hence, this systematic review aimed to provide a comprehensive overview of the microbiology of traditional Ethiopian fermented milk products, including ergo (spontaneously fermented whole milk), dhanaan (fermented …

Gut Microbiome And Hepatic Transcriptomic Determinants Of Hcc Development In Mice With Metabolic Dysfunction-Associated Steatohepatitis, Lillian I Dolapchiev, Kristyn A Gonzales, Lorenzo R Cruz, Mihai Gagea, Heather L Stevenson, Suet-Ying Kwan, Laura Beretta

Faculty, Staff and Student Publications

Purpose: Hepatocellular carcinoma (HCC) related to metabolic dysfunction-associated steatotic liver disease (MASLD) is often diagnosed at a late stage, and its incidence is increasing. Predictive biomarkers are therefore needed to identify individuals at high risk of HCC. We aimed to characterize the gut microbiome and hepatic transcriptome associated with HCC development in female mice with hepatocyte-deletion of Pten (HepPten -). These mice present with large variations in HCC development, making them a powerful model for biomarker discovery.

Methods & results: Sequencing of stool 16S and hepatic RNA was performed on a first set of mice. Among all liver histology …

Usp22 Overexpression Fails To Augment Tumor Formation In Mmtv-Erbb2 Mice But Loss Of Function Impacts Mmtv Promoter Activity, Xianghong Kuang, Andrew Salinger, Fernando Benavides, William J Muller, Sharon Y R Dent, Evangelia Koutelou

Faculty, Staff and Student Publications

The Ubiquitin Specific Peptidase 22 (USP22), a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) histone modifying complex, is overexpressed in multiple human cancers, but how USP22 impacts tumorigenesis is not clear. We reported previously that Usp22 loss in mice impacts execution of several signaling pathways driven by growth factor receptors such as erythroblastic oncogene B b2 (ERBB2). To determine whether changes in USP22 expression affects ERBB2-driven tumorigenesis, we introduced conditional overexpression or deletion alleles of Usp22 into mice bearing the Mouse mammary tumor virus-Neu-Ires-Cre (MMTV-NIC) transgene, which drives both rat ERBB2/NEU expression and Cre recombinase activity from the MMTV promoter resulting …

Protection Against Fibrosis By A Bacterial Consortium In Metabolic Dysfunction-Associated Steatohepatitis And The Role Of Amino Acid Metabolism, Suet-Ying Kwan, Kristyn A Gonzales, Mohamed A Jamal, Heather L Stevenson, Lin Tan, Philip L Lorenzi, P Andrew Futreal, Ernest T Hawk, Joseph B Mccormick, Susan P Fisher-Hoch, Robert R Jenq, Laura Beretta

Faculty, Staff and Student Publications

The gut microbiota drives progression to liver fibrosis, the main determinant of mortality in metabolic dysfunction-associated steatohepatitis (MASH). In this study, we aimed to identify bacterial species associated with protection against liver fibrosis in a high-risk population, and test their potential to protect against liver fibrosis in vivo. Based on stool shotgun metagenomic sequencing of 340 subjects from a population cohort disproportionally affected by MASH, we identified bacterial species from the Bacteroidales and Clostridiales orders associated with reduced risk of liver fibrosis. A bacterial consortium was subsequently tested in a mouse model of MASH, which demonstrated protective effects against …

Usp22 Overexpression Fails To Augment Tumor Formation In Mmtv-Erbb2 Mice But Loss Of Function Impacts Mmtv Promoter Activity, Xianghong Kuang, Andrew Salinger, Fernando Benavides, William J Muller, Sharon Y R Dent, Evangelia Koutelou

Faculty, Staff and Student Publications

The Ubiquitin Specific Peptidase 22 (USP22), a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) histone modifying complex, is overexpressed in multiple human cancers, but how USP22 impacts tumorigenesis is not clear. We reported previously that Usp22 loss in mice impacts execution of several signaling pathways driven by growth factor receptors such as erythroblastic oncogene B b2 (ERBB2). To determine whether changes in USP22 expression affects ERBB2-driven tumorigenesis, we introduced conditional overexpression or deletion alleles of Usp22 into mice bearing the Mouse mammary tumor virus-Neu-Ires-Cre (MMTV-NIC) transgene, which drives both rat ERBB2/NEU expression and Cre recombinase activity from the MMTV promoter resulting …

Interleukin-1beta And Inflammasome Expression In Spinal Cord Following Chronic Constriction Injury In Male And Female Rats, Suzanne M Green-Fulgham, Jayson B Ball, Andrew J Kwilasz, Michael E Harland, Matthew G Frank, Joseph M Dragavon, Peter M Grace, Linda R Watkins

Faculty, Staff and Student Publications

Females represent a majority of chronic pain patients and show greater inflammatory immune responses in human chronic pain patient populations as well as in animal models of neuropathic pain. Recent discoveries in chronic pain research have revealed sex differences in inflammatory signaling, a key component of sensory pathology in chronic neuropathic pain, inviting more research into the nuances of these sex differences. Here we use the chronic constriction injury (CCI) model to explore similarities and differences in expression and production of Inflammatory cytokine IL-1beta in the lumbar spinal cord, as well as its role in chronic pain. We have discovered …

Identifying Genomic Data Sources From Biomedical Literature, Xu Zuo, Ashley Gilliam, Yan Hu, Kalpana Raja, Kirk Roberts, Hua Xu

Faculty, Staff and Student Publications

Genomic research is becoming increasingly data-intensive, yet the proper reference of data remains a persistent challenge. Despite various efforts to establish and standardize data citation practices, scientists frequently fall short of accurately referencing data in their papers. This deficiency complicates the attribution of contributions to data providers and impedes the reproducibility of findings in genomic research. This study addresses this gap by introducing a gold standard corpus designed to identify mentions of genomic data sources and associated attributes, thereby offering insights into data source availability and accessibility. Within this corpus, we categorize entities into six classes, encompassing three primary entities …

Dissecting The Shared Genetic Architecture Between Alzheimer’S Disease And Frailty: A Cross-Trait Meta-Analyses Of Genome-Wide Association Studies, Nitesh Enduru, Brisa S Fernandes, Zhongming Zhao

Faculty, Staff and Student Publications

Introduction: Frailty is the most common medical condition affecting the aging population, and its prevalence increases in the population aged 65 or more. Frailty is commonly diagnosed using the frailty index (FI) or frailty phenotype (FP) assessments. Observational studies have indicated the association of frailty with Alzheimer's disease (AD). However, the shared genetic and biological mechanism of these comorbidity has not been studied.

Methods: To assess the genetic relationship between AD and frailty, we examined it at single nucleotide polymorphism (SNP), gene, and pathway levels.

Results: Overall, 16 genome-wide significant loci (15 unique loci) (p meta-analysis < 5 × 10-8) and 22 genes (21 unique genes) were identified between AD and frailty using cross-trait meta-analysis. The 8 shared loci implicated 11 genes: CLRN1-AS1, CRHR1 …

Mining The Qhapaq Ñan With Micaela De Vivero: Decolonial Cords, Joy Sperling

Faculty Publications

No abstract provided.

Enhancing The Textbook’S Cultural Content Within The University Museum: Students’ Perceptions Of Two Activities, Nausica Marcos Miguel, Megan Hancock

Faculty Publications

No abstract provided.

Inquiry, Value, And Some Peculiarities Of The Pyrrhonist’S Psychology, Chelsea Bowden

Faculty Publications

No abstract provided.

Puerto Rican Welfare Queens And The Semiotics Ofrespectability: The Language Of Race, Class, Andgender, Mary Beaton

Faculty Publications

No abstract provided.

Resourceful Remedies: Herbal Medicines In Indigenous Villages Of Northern Thailand, Ava Peyton

The Synapse: Intercollegiate science magazine

No abstract provided.

In The Shadow Of The Moon: Reflections On The April 2024 Total Solar, Danielle Oliver

The Synapse: Intercollegiate science magazine

No abstract provided.

Issue 40

The Synapse: Intercollegiate science magazine

No abstract provided.

Utah Farmers Market Manager Handbook, Gwen Crist

Environment and Society Faculty Publications

Welcome to the Utah Farmers Market Manager Handbook, designed by the Utah Farmers Market Network for market managers like you! We’re thrilled to support you in your job as a market manager by providing this Handbook of information and tools you’ll need to start a market from scratch or to grow your market, along with helpful links and resources, tips, and best practices for running a successful market.

Complex Dynamics Of Coral Gene Expression Responses To Low Ph Across Species, Veronica Z. Radice, Ana Martinez, Adina Paytan, Donald C. Potts, Daniel J. Barshis

Biological Sciences Faculty Publications

Coral capacity to tolerate low pH affects coral community composition and, ultimately, reef ecosystem function. Low pH submarine discharges (‘Ojo’; Yucatán, México) represent a natural laboratory to study plasticity and acclimatization to low pH in relation to ocean acidification. A previous >2‐year coral transplant experiment to ambient and low pH common garden sites revealed differential survivorship across species and sites, providing a framework to compare mechanistic responses to differential pH exposures. Here, we examined gene expression responses of transplants of three species of reef‐building corals (Porites astreoides, Porites porites and Siderastrea siderea) and their algal endosymbiont communities …

Receptor-Targeted Next-Generation Probiotics Ameliorate Mammalian Colitis, Nicholas L. F. Gallina, Vignesh Nathan, Akshay Krishnakumar, Dongqi Liu, Rishi Drolia, Nicole Irrizary Tardi, Yang Fu, Manalee Samadar, Shivendra Tenguria, Alvin Cai, Ruth Eunice Centeno-Martinez, Timothy A. Johnson, Abigail Cox, Lavanya Reddivari, Bruce Applegate, Xingjian Bai, Luping Xu, Deepti Tanjore, Ramesh Vemulapalli, Rahim Rahimi, Arun K. Bhunia

Biological Sciences Faculty Publications

Introduction: a loss of intestinal barrier function, inflammation, and an elevated expression of epithelial heat shock protein 60 (Hsp60) are features of an inflamed bowel. Probiotics have been used to alleviate colitis-induced pathologies, but offer poor adhesion and adaptation to the diseased gut. We hypothesize that enhancing probiotic adhesion in the inflamed bowel may ameliorate such pathologies. Listeria adhesion protein (LAP; 94-kDa acetaldehyde alcohol dehydrogenase) aids Listeria attachment to the epithelial cells by interacting with the mammalian receptor Hsp60. Bioengineered Lactobacillus casei probiotics (BLPs) expressing LAP showed strong interaction with epithelial Hsp60, a high immunomodulatory response, and sustained epithelial barrier …

Unconscionability And Poverty, Mark G. Kelman

SMU Law Review Forum

Matthew Desmond made the claim in Evicted, his powerful work on housing insecurity, that those concerned with alleviating poverty should focus not merely on ensuring that poor people have higher disposable incomes, but on countering the exploitative price gouging that depresses the value of whatever income they have. This suggests the possibility that it might be a worthwhile anti-poverty strategy for courts to use the unconscionability doctrine to regulate exploitative contracts.

Three main issues follow from considering this possibility: (1) Do the poor actually pay more for goods of the same quality? (2) If they indeed pay more, do …

The Cost Of Clarity: Closing The Floodgates On Wotus Ambiguity And The Bleak Future Of Wetlands Protections, Casey E. Lindstrom

Case Western Reserve Law Review

No abstract provided.

Overcoming Unreasonably Burdensome Restrictions On The Use Of Farmland For Solar Generation, Matthew Eisenson

Case Western Reserve Law Review

No abstract provided.

Repatriating The Dead: The Necessity Of An Enslaved Peoples’ Grave Repatriation Act To Break One Of The Surviving Chains Of Slavery, Nathaniel Gray Sommers

Case Western Reserve Law Review

No abstract provided.

Science And The Pulpit: Clerical Perspectives On Science And Religion In The United States, Shiri Noy, Timothy L. O'Brien

Faculty Publications

No abstract provided.

Efficacy Of Bacillus-Based Probiotic And Nspase Supplementation On Growth Performance And Gut Health Of Broilers Fed High Level Of Palm Kernel Meals Under High Stocking Density, Nurul Imawati

Chulalongkorn University Theses and Dissertations (Chula ETD)

Palm kernel meal (PKM) is a by-product of the oil palm industry with significant potential in poultry feed, although its high content of anti-nutritional factors limits its utilization. It is hypothesized that dietary supplementation with fiber-degrading enzymes and probiotics may enhance the use of PKM. This study investigated the effects of Bacillus-based probiotics (PRO) and non-starch polysaccharide enzymes (NSPase, mannanase, and xylanase) on broiler performance and gut health when fed a high level of PKM under high stocking density (HSD, Experiment 1) and normal stocking density (NSD, Experiment 2). In Experiment 1, 4,480 mixed-sex Ross308 broilers were allocated to eight …

มาตรการเพื่อส่งเสริมธุรกิจอาหารทางเลือกจากพืช, ณัฏฐา สงวนพงษ์

Chulalongkorn University Theses and Dissertations (Chula ETD)

เอกัตศึกษาฉบับนี้ มีวัตถุประสงค์เพื่อมีมาตรการ หรือแนวคิดริเริ่มเพื่อส่งเสริมธุรกิจอาหารทางเลือกจากพืชในประเทศไทยให้เติบโตมากขึ้น เพื่อสร้างประโยชน์ในระยะยาวให้กับเศรษฐกิจและสังคมไทยอย่างยั่งยืน ประโยชน์ของธุรกิจดังกล่าวส่งผลกระทบในด้านต่าง ๆ ดังนี้ (1) ประโยชน์ด้านสุขภาพ สามารถช่วยให้มีสุขภาพดีขึ้น รวมถึงลดความเสี่ยงต่อโรคต่าง ๆ (2) ประโยชน์ด้านสิ่งแวดล้อม การรับประทานอาหารทางเลือกจากพืชใช้ทรัพยากรต่าง ๆ เช่น ที่ดิน แหล่งน้ำ และพลังงาน น้อยกว่าอาหารที่มีส่วนผสมจากเนื้อสัตว์ จึงถือเป็นการประหยัดพลังงานและช่วยรักษาสิ่งแวดล้อมได้เป็นอย่างดี (3) ประโยชน์ด้านความมั่นคงทางอาหาร สามารถช่วยลดความเสี่ยงจากการขาดแคลนอาหาร เนื่องจากกระบวนการผลิตอาหารทางเลือกจากพืชใช้ทรัพยากรด้านต่าง ๆ น้อยกว่าผลิตภัณฑ์จากสัตว์ และ (4) ประโยชน์ด้านสวัสดิภาพสัตว์ การรับประทานอาหารทางเลือกจากพืชถือเป็นการคุ้มครองสัตว์ เพราะเป็นการลดการผลิตผลิตภัณฑ์จากเนื้อสัตว์ในฟาร์มเอกัตศึกษาฉบับนี้ มีการดำเนินการวิจัยด้วยวิธีการศึกษาเชิงเอกสาร (Documentary Research) โดยการศึกษาค้นคว้า รวบรวม วิเคราะห์ข้อมูล จากหนังสือ บทความ ตำรา วิทยานิพนธ์ เอกัตศึกษา เอกสารสิ่งพิมพ์ หลักภาษีอากร โดยมีการใช้ฐานข้อมูลออนไลน์ ที่มีบุคคลอื่นได้บันทึกหรือตีพิมพ์เผยแพร่ไว้เกี่ยวกับมาตรการเพื่อส่งเสริมธุรกิจอาหารทางเลือกจากพืช ทั้งในประเทศไทยและต่างประเทศ จากนั้นนำข้อมูลที่รวบรวมได้มาทำการศึกษา เรียบเรียง และวิเคราะห์อย่างเป็นระบบ เพื่อเสนอแนวทางการสร้างแรงจูงใจให้กับผู้ประกอบธุรกิจอาหารทางเลือกจากพืชจากการศึกษา พบว่า ในปัจจุบัน ไทยยังขาดมาตรการส่งเสริมธุรกิจอาหารทางเลือกจากพืชที่ชัดเจนและครอบคลุม เมื่อเทียบกับหลายประเทศที่ให้ความสำคัญกับเรื่องนี้ เช่น สหรัฐอเมริกา สหภาพยุโรป และสิงคโปร์ ทั้งนี้ เพื่อส่งเสริมธุรกิจอาหารทางเลือกจากพืชในไทยให้เติบโตอย่างยั่งยืน ควรมีการดำเนินการดังนี้ (1) จัดทำแผนยุทธศาสตร์ระดับชาติ และกฎหมายเฉพาะเพื่อส่งเสริมอาหารทางเลือกจากพืช: กำหนดเป้าหมายและแนวทางการดำเนินงานที่ชัดเจน (2) บูรณาการนโยบาย เชื่อมโยงนโยบายด้านอาหารกับนโยบายอื่น ๆ เช่น สุขภาพ สิ่งแวดล้อม และเศรษฐกิจ รวมถึงการสนับสนุนการวิจัยและพัฒนา เพื่อส่งเสริมการพัฒนานวัตกรรม ซึ่งจะเป็นองค์ประกอบสำคัญในการพัฒนาผลิตภัณฑ์ใหม่ ๆ และเทคโนโลยีที่เกี่ยวข้อง (3) ส่งเสริมด้านสิทธิประโยชน์ทางภาษีเพื่อส่งเสริมธุรกิจอาหารทางเลือกจากพืช ทั้งในส่วนที่ส่งผลกับอาหารทางเลือกจากพืชโดยตรง เช่น การพิจารณาปรับลดอัตราภาษีมูลค่าเพิ่มสำหรับอาหารทางเลือกจากพืช และส่วนที่เกี่ยวข้องกับการให้สิทธิประโยชน์ทางภาษีทางอ้อม เช่น การหักค่าใช้จ่ายที่ใช้สำหรับการวิจัย (4) สร้างความตระหนักรู้ และประชาสัมพันธ์ข้อมูลเกี่ยวกับประโยชน์ของอาหารจากพืช ทั้งต่อผู้บริโภคเอง และต่อสังคมในภาพรวม (5) สนับสนุนเกษตรกร และส่งเสริมการปลูกพืชที่ใช้เป็นวัตถุดิบในการผลิตอาหารจากพืชการดำเนินการเหล่านี้จะช่วยให้ไทยมีอุตสาหกรรมอาหารทางเลือกจากพืชที่แข็งแกร่ง สามารถแข่งขันในตลาดโลก และตอบสนองความต้องการของผู้บริโภคที่ใส่ใจสุขภาพและสิ่งแวดล้อมมากขึ้น นอกจากนี้ …

Curatorial Project For Art Exhibition: "Line", Yunjiao Ji

Chulalongkorn University Theses and Dissertations (Chula ETD)

The LINE exhibition is more than a display of artistic projects; it is a comprehensive exploration of rural development in China through artistic intervention, with an educational focus that transcends aesthetics. In recent years, art-driven rural development has gained attention in China, characterized by unique regional and cultural features. This research investigates its theoretical foundations and practical outcomes, aiming to enhance awareness and identify pathways adapted to rural communities, contemporary art, and societal needs. Rooted in Mao Zedong's "Art Serving the People" concept, the study emphasizes art’s connection to the lives of the masses, including rural communities. Case studies such …

Usft 2024-2025 Usf Libraries Annual Report, Usf Libraries

Library Annual Reports

No abstract provided.

Agent-Interacted Big Data-Driven Dynamic Cartoon Video Generator, Yasmin Makki Mohialden, Abbas Akram Khorsheed, Nadia Mahmood Hussien

Mesopotamian Journal of Big Data

This study presents a novel method for animating videos using three Kaggle cartoon faces data sets. Dynamic interactions between cartoon agents and random backgrounds, as well as Gaussian blur, rotation, and noise addition, make cartoon visuals look better. This approach also evaluates video quality and animation design by calculating the backdrop colour's average and standard deviation, ensuring visually appealing material. This technology uses massive datasets to generate attractive animated videos for entertainment, teaching, and marketing.

The Impact Of A Virtual Wilderness On Subjective Happiness: Enhancing Happiness Through Nature Imagery, Brittany Magid

Antioch University Dissertations & Theses

This dissertation explores the impact of virtual nature imagery on subjective happiness, investigating whether exposure to virtual nature environments can enhance self-reported happiness levels. While direct interaction with natural environments has been linked to increased happiness, this study seeks to evaluate the feasibility of virtual alternatives. Using a quantitative approach, three types of virtual experiences: nature, active control (office environment), and a control condition (gray panel) were compared to assess their influence on acute happiness. Participants (N = 409) were randomly assigned to one of these conditions and completed the Subjective Happiness Scale (SHS) after viewing a 15-second video. Demographic …