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2024

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Mesoporous Silica Administration As A New Strategy In The Management Of Warfarin Toxicity: An In-Vitro And In-Vivo Study, Fatemeh Farjadian, Fatemeh Parsi, Reza Heidari, Khatereh Zarkesh, Hamid Reza Mohammadi, Soliman Mohammadi-Samani, Lobat Tayebi Jan 2024

Mesoporous Silica Administration As A New Strategy In The Management Of Warfarin Toxicity: An In-Vitro And In-Vivo Study, Fatemeh Farjadian, Fatemeh Parsi, Reza Heidari, Khatereh Zarkesh, Hamid Reza Mohammadi, Soliman Mohammadi-Samani, Lobat Tayebi

Electrical & Computer Engineering Faculty Publications

Purpose: Warfarin is one of the most widely used anticoagulants that functions by inhibiting vitamin K epoxide reductase. Warfarin overdose, whether intentional or unintentional, can cause life-threatening bleeding. Here, we present a novel warfarin adsorbent based on mesoporous silica that could serve as an antidote to warfarin toxicity.

Method: Amino-functionalized mesoporous silica (MS-NH₂) was synthesized based on the cocondensation method through a soft template technique followed by template removal. The prepared structure and functional group were studied by Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD). Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) checked the morphology. The …


An Overview Of The Relationships Between The Food Industry And Nanotechnology, Mehdi Koushki, Nasrin Amiri-Dashatan, Hossein Pourghadamyari, Hadi Khodabandehloo, Fatemeh Bagheri, Masoumeh Farahani, Lobat Tayebi Jan 2024

An Overview Of The Relationships Between The Food Industry And Nanotechnology, Mehdi Koushki, Nasrin Amiri-Dashatan, Hossein Pourghadamyari, Hadi Khodabandehloo, Fatemeh Bagheri, Masoumeh Farahani, Lobat Tayebi

Electrical & Computer Engineering Faculty Publications

Background and Objective: Due to the growth of the global population, food demands are increasing. Hence, the need to develop more efficient methods for producing better quality, safer, and more sustainable food seems essential. In the past decades, the use of nanoscale materials has increased greatly due to the unique chemical, physical, and biological characteristics of nanomaterials compared to bulk materials. This research presents nanotechnology role in improving sensorial properties (taste, appearance, and texture) and safety aspects as well as processing and packaging of foods. The use of nano-omics-based technologies and artificial intelligence-nanotechnology-based technologies in the food industry is also …


A Modified Nucleoside O6-Methyl-2'-Deoxyguanosine-5'-Triphosphate Exhibits Anti-Glioblastoma Activity In A Caspase-Independent Manner., Zi-Hui Wang, Jin Li, Qian Liu, Jian-Chang Qian, Qing-Qing Li, Qing-Yu Wang, Lv-Tao Zeng, Si-Jia Li, Xin Gao, Jia-Xin Pan, Xu-Fan Gao, Kun Wu, Guo-Xin Hu, Tomoo Iwakuma, Jian-Ping Cai Jan 2024

A Modified Nucleoside O6-Methyl-2'-Deoxyguanosine-5'-Triphosphate Exhibits Anti-Glioblastoma Activity In A Caspase-Independent Manner., Zi-Hui Wang, Jin Li, Qian Liu, Jian-Chang Qian, Qing-Qing Li, Qing-Yu Wang, Lv-Tao Zeng, Si-Jia Li, Xin Gao, Jia-Xin Pan, Xu-Fan Gao, Kun Wu, Guo-Xin Hu, Tomoo Iwakuma, Jian-Ping Cai

Manuscripts, Articles, Book Chapters and Other Papers

Resistance to temozolomide (TMZ), the frontline chemotherapeutic agent for glioblastoma (GBM), has emerged as a formidable obstacle, underscoring the imperative to identify alternative therapeutic strategies to improve patient outcomes. In this study, we comprehensively evaluated a novel agent, O6-methyl-2'-deoxyguanosine-5'-triphosphate (O6-methyl-dGTP) for its anti-GBM activity both in vitro and in vivo. Notably, O6-methyl-dGTP exhibited pronounced cytotoxicity against GBM cells, including those resistant to TMZ and overexpressing O6-methylguanine-DNA methyltransferase (MGMT). Mechanistic investigations revealed that O6-methyl-dGTP could be incorporated into genomic DNA, disrupting nucleotide pools balance, and inducing replication stress, resulting in S-phase arrest and DNA damage. The compound exerted its anti-tumor properties …


Upcycling Imperfect Broccoli And Carrots Into Healthy Snacks Using An Innovative 3d Food Printing Approach, Safoura Ahmadzadeh, Taylor Clary, Alex Rosales, Ali Ubeyitogullari Jan 2024

Upcycling Imperfect Broccoli And Carrots Into Healthy Snacks Using An Innovative 3d Food Printing Approach, Safoura Ahmadzadeh, Taylor Clary, Alex Rosales, Ali Ubeyitogullari

Food Science Faculty Publications and Presentations

Vegetables are healthy foods with nutritional benefits; however, nearly one-third of the world's vegetables are lost each year, and some of the losses happen due to the imperfect shape of the vegetables. In this study, imperfect vegetables (i.e., broccoli and carrots) were upcycled into freeze-dried powders to improve their shelf-life before they were formed into food inks for 3D printing. The rheology of the food inks, color analysis of the uncooked and cooked designs, and texture analysis of the cooked designs were determined. The inks with 50% and 75% vegetables provided the best printability and shape fidelity. 3D printing at …


Foreword: Artificially Intelligent Innovation And Justice, Carla L. Reyes Jan 2024

Foreword: Artificially Intelligent Innovation And Justice, Carla L. Reyes

SMU Science and Technology Law Review

No abstract provided.


If Held Holds: Held V. Montana And The Future Of Constitutional Environmental Litigation, Leonora Owsley Jan 2024

If Held Holds: Held V. Montana And The Future Of Constitutional Environmental Litigation, Leonora Owsley

SMU Science and Technology Law Review

The State of Montana is one of three states whose constitutions presently contain a “green amendment[.]” These amendments, enshrined in their respective Bills of Rights, protect a citizen’s fundamental right to a clean and healthy environment, ideally ensuring that the state’s government cannot infringe upon that right. However, following the green amendment’s adoption in 1972, Montana’s law still prioritized its extractive energy and hard rock mining industries over its citizens’ environmental rights. Now, that landscape is beginning to change. In 2011, Montana adopted an amended State Energy Policy Act, which expressly forbade its agencies from considering the effects of climate …


Advancing Environmental Engineering: The Role Of Artificial Intelligence In Sustainable Solutions - A Short Review, Amirreza Talaie, Hesam Kamyab, Ashkan Razmfarsa Jan 2024

Advancing Environmental Engineering: The Role Of Artificial Intelligence In Sustainable Solutions - A Short Review, Amirreza Talaie, Hesam Kamyab, Ashkan Razmfarsa

Management Faculty Publications

Artificial intelligence (AI) has emerged as a transformative force in environmental engineering, offering innovative solutions to complex environmental challenges. From air pollution monitoring and water resource management to waste management, climate change mitigation, and ecological preservation, AI is revolutionizing the way we address environmental issues. Machine learning, neural networks, and other AI technologies are enabling more accurate predictions, optimizing resource use, and improving conservation efforts. However, despite its many advantages, AI also faces challenges such as data availability, energy consumption, ethical concerns, and the need for transparency. This review explores the diverse applications of AI in environmental engineering, highlighting the …


Why Human Rights? A Philosophical Guide, Eric Blumenson Jan 2024

Why Human Rights? A Philosophical Guide, Eric Blumenson

Suffolk University Law School Faculty Works

Why Human Rights addresses universal human rights as moral mandates – rights to justice that all persons have by virtue of their humanity alone. These are not the legal rights of statutes and treaties, but moral rights of the kind Gandhi, King, and Mandela invoked to oppose unjust laws. All such rights presuppose three claims: (1) that some duties of justice apply universally, (2) that all human beings have equal moral significance, and (3) that states must protect or serve certain individual interests regardless of the societal impact of doing so Can these three premises be justified? Is the human …


Notes On Patagium Morphology In The Gliding Flat-Tailed House Gecko (Hemidactylus Platyurus), Amber M. Petty, Tony Gamble, Aaron H. Griffing Jan 2024

Notes On Patagium Morphology In The Gliding Flat-Tailed House Gecko (Hemidactylus Platyurus), Amber M. Petty, Tony Gamble, Aaron H. Griffing

Biological Sciences Faculty Research and Publications

Several species of geckos have independently evolved patagia, membranous features that facilitate gliding. Detailed morphological investigations of gecko patagia have largely been limited to gliding members of the genus Gekko (formerly in the genus Ptychozoon). Herein we describe the morphology of gliding patagia of the Flat-tailed House Gecko (Hemidactylus platyurus), a species with an independent evolutionary origin of gliding patagia from Gekko and an important species for researching gliding biomechanics. We compared morphology of H. platyurus with a closely related non-gliding species, the Common House Gecko (Hemidactylus frenatus). Using external examination and histological techniques, we …


Bacillus Subtilis-Derived Peptides Disrupt Quorum Sensing And Biofilm Assembly In Multidrug-Resistant Staphylococcus Aureus, Kyle R. Leistikow, Daniel S. May, Won Se Suh, Gabriel Vargas Asensio, Adam J. Schaenzer, Cameron R. Currie, Krassimira R. Hristova Jan 2024

Bacillus Subtilis-Derived Peptides Disrupt Quorum Sensing And Biofilm Assembly In Multidrug-Resistant Staphylococcus Aureus, Kyle R. Leistikow, Daniel S. May, Won Se Suh, Gabriel Vargas Asensio, Adam J. Schaenzer, Cameron R. Currie, Krassimira R. Hristova

Biological Sciences Faculty Research and Publications

Multidrug-resistant Staphylococcus aureus is one of the most clinically important pathogens in the world, with infections leading to high rates of morbidity and mortality in both humans and animals. The ability of S. aureus to form biofilms protects cells from antibiotics and promotes the transfer of antibiotic resistance genes; therefore, new strategies aimed at inhibiting biofilm growth are urgently needed. Probiotic species, including Bacillus subtilis, are gaining interest as potential therapies against S. aureus for their ability to reduce S. aureus colonization and virulence. Here, we search for strains and microbially derived compounds with strong antibiofilm activity against multidrug-resistant S. …


Not Just Bony Fish: All Nonmammalian And Nonavian Animals Are Neglected In Both Welfare And General Research, Jennifer A. Mather Ph.D. Jan 2024

Not Just Bony Fish: All Nonmammalian And Nonavian Animals Are Neglected In Both Welfare And General Research, Jennifer A. Mather Ph.D.

Animal Sentience

The lack of research on fish welfare highlighted by Oldfield & Bonano (2024) is only part of a more general problem: a relative neglect of animals other than mammals and birds. The causes are our lack of knowledge, our negative view of what we consider to be “lower” animals and our underestimation of their intelligence and sensitivity. Our estimation will increase as our knowledge increases. As a broader view spreads to the public through the media, it should gradually increase the demand to expand both research and welfare, especially beyond mammals and birds.


Pati Hill Collection - Artist Books, Arcadia University Jan 2024

Pati Hill Collection - Artist Books, Arcadia University

Finding Aids

Finding aid for the Pati Hill - Artist Books Collection at the Arcadia University Archives.


Pati Hill Collection Unframed Artwork - General, Arcadia University Jan 2024

Pati Hill Collection Unframed Artwork - General, Arcadia University

Finding Aids

Finding aid for the Pati Hill Collection Unframed Artwork - General at the Arcadia University Archives.


Examining The Link Between Autistic Personality Traits And Processing Of Metonymy, Miranda Moe Jan 2024

Examining The Link Between Autistic Personality Traits And Processing Of Metonymy, Miranda Moe

Honors Theses

Previous research has investigated the real-time processing and offline interpretation of metonyms. This work has generally shown that readers experience longer processing times for metonyms versus control nouns because of the extra time needed to access the figurative sense of a metonym. Recent research has also demonstrated different processing patterns on nonliteral language for individuals with autism spectrum disorder compared to typically developing participants. The current study was designed to explore whether previous findings on the processing of metonymy are modulated by individual differences in autistic personality traits. Through an eye-tracking during reading experiment, participants read sentences in which factors …


Capital Punishment In Context: Kenneth Smith And The Eight Amendment, Elizabeth Stamper Jan 2024

Capital Punishment In Context: Kenneth Smith And The Eight Amendment, Elizabeth Stamper

Public Interest Law Reporter

No abstract provided.


What A Waste: The Prosecution Of Hazardous Substances Crimes During The Trump Administration, Joshua Ozymy, Ph.D., Melissa Jarrell Ozymy, Ph.D. Jan 2024

What A Waste: The Prosecution Of Hazardous Substances Crimes During The Trump Administration, Joshua Ozymy, Ph.D., Melissa Jarrell Ozymy, Ph.D.

Public Interest Law Reporter

The Trump Administration went to great lengths to roll back environmental regulatory and enforcement efforts. Yet, researchers know very little about the impact of the Administration on the criminal prosecution of hazardous substance crimes. This study utilizes content analysis of EPA criminal investigations leading to prosecution during the Trump Era to analyze charging and sentencing patterns and illustrate the greater themes that emerged during this period. Prosecutions are dominated by hazardous waste (48%), pesticide (41%), and lead-based paint (11%) crimes. Results show prosecutors were able to pursue crimes involving significant harm and culpable conduct, while securing over $90 million in …


Is Sustainable Finance The Solution To Funding The U.N. Sdgs? Exploring The Potential Of Sustainable Finance Strategies In Achieving Climate Action, Amanda Scheichet Jan 2024

Is Sustainable Finance The Solution To Funding The U.N. Sdgs? Exploring The Potential Of Sustainable Finance Strategies In Achieving Climate Action, Amanda Scheichet

Public Interest Law Reporter

No abstract provided.


Pathological Characterization Of Cryptosporidiosis In Naturally Infected Hybrid Converter Breeds Of Meleagris Gallopavo, Shady Shalaby, Walaa Awadin, Sanaa Salem, Ahmed El- Shaieb Jan 2024

Pathological Characterization Of Cryptosporidiosis In Naturally Infected Hybrid Converter Breeds Of Meleagris Gallopavo, Shady Shalaby, Walaa Awadin, Sanaa Salem, Ahmed El- Shaieb

Mansoura Veterinary Medical Journal

Background: Rearing of the hybrid converter breed of turkey (Meleagris gallopavo) is becoming more popular in Egyptian farms because of its high meat production; however, many pathogens affect this benefit.

Objectives: This study aimed to investigate the occurrence and pathological impact of cryptosporidiosis in hybrid converter breeds.

Methods: Regular visits to turkey farms of hybrid converter breeds in the delta region of Egypt were conducted during 2022 and 2023. Clinical examination of the diseased birds was performed and recorded. Following the clinical examination, the diseased turkeys were euthanized and necropsied. Freshly dead birds were then necropsied. The …


Effectiveness Of Cleanup And Dredging Operations On Some Heavy Metal Residues In Fish Flesh From Manzala Lake, Egypt, Heba Rahmo, Samir Abd-Elghany, Amira Ibrahim Zakaria Jan 2024

Effectiveness Of Cleanup And Dredging Operations On Some Heavy Metal Residues In Fish Flesh From Manzala Lake, Egypt, Heba Rahmo, Samir Abd-Elghany, Amira Ibrahim Zakaria

Mansoura Veterinary Medical Journal

OBJECTIVES: The current study aimed to evaluate the effectiveness of cleanup and dredging operations in Manzala Lake on the levels of mercury, arsenic, lead, and cadmium in fish muscles and compare them with the concentrations previously recorded in the same lake before treatment. METHODS: A total of 180 fish samples, including 60 each of Nile tilapia (Oreochromis niloticus), flathead grey mullet (Mugil cephalus), and African catfish (Clarias gariepinus), were analyzed using atomic absorption spectrophotometry. RESULTS: The mean concentrations (mg/kg) of Hg, As, Pb, and Cd in tilapia were 0.01 ± 0.03, 3.16 ± 0.35, 1.01 ± 0.16, and 0.12 ± …


The Targeted Application Of Colour Doppler Ultrasonography In Dairy Cows Management, Mohammed A Elmetwally, Heinrich Bollwein, Amira M Mostagir, Alaa Samy, Fatma Adlan, Sara Shalapy, Amal Helmy, Yasser Y. Lenis, Mariam M Rabie, Mohamed Gohar, Walid Tawfik, Heba A Sharawy Jan 2024

The Targeted Application Of Colour Doppler Ultrasonography In Dairy Cows Management, Mohammed A Elmetwally, Heinrich Bollwein, Amira M Mostagir, Alaa Samy, Fatma Adlan, Sara Shalapy, Amal Helmy, Yasser Y. Lenis, Mariam M Rabie, Mohamed Gohar, Walid Tawfik, Heba A Sharawy

Mansoura Veterinary Medical Journal

The management of reproduction in dairy herds has profited tremendously from technical improvements, greater usage of ovulation synchronization procedures, and fixed-time automated monitoring devices. The purpose of this review article is to highlight the importance of noninvasive color Doppler ultrasound imaging based on the target reproductive management of dairy cows. Noninvasive measurement of uterine and vaginal blood flow in dairy cows is variable during the estrous cycle, pregnancy, and puerperium. Transrectal uterine and vaginal arterial blood flow changes can be utilized to determine changes in female genital functions during the estrous cycle, pregnancy, and puerperium, according to the findings of …


Chicken Infectious Anemia Virus: A Causative Agent Of Immunosuppressive Diseases In Poultry Industry, Amal R. Abdel Aziz, Kh. M. Elbayoumi, Sanaa S. A. Awad, Abou El-Azm Jan 2024

Chicken Infectious Anemia Virus: A Causative Agent Of Immunosuppressive Diseases In Poultry Industry, Amal R. Abdel Aziz, Kh. M. Elbayoumi, Sanaa S. A. Awad, Abou El-Azm

Mansoura Veterinary Medical Journal

Due to the emerging status of chicken infectious anemia in Africa, especially Egypt, and its resemblance to infectious bursal disease, it was needed to look into this disease. This review article's goal is to draw attention to how the chicken anemia virus (CAV) affects the poultry industry and how vaccinations can help keep the disease under control. CAV is an immunosuppressive disease and therefore, causes great economic losses to the poultry industry. It is caused by the chicken infectious anemia virus (CIAV), a member of the genus Gyrovirus family Annelloviridae. Progenitor cells of the erythroid and myeloid series are the …


Characterization Of Multidrug-Resistant E. Coli O157 Isolated From Buffalo Meat Marketed In Dakahlia Province., Amira Mahmoud El- Sayeh Jan 2024

Characterization Of Multidrug-Resistant E. Coli O157 Isolated From Buffalo Meat Marketed In Dakahlia Province., Amira Mahmoud El- Sayeh

Mansoura Veterinary Medical Journal

Objective: To identify the frequency of STEC in the buffalo meat samples tested. Samples: 110 samples Methods: A total of 110 buffalo meat samples were purchased from retail stores in Mansoura, Egypt. Each individual sample was packaged into a sterile plastic bag, and transported in an insulated icebox to the laboratory as soon as possible. The microbiological examination was performed at the research laboratory of the Food Hygiene and Control Department, Faculty of Veterinary Medicine, Mansoura University. Results: The conventional technique for isolation of this pathogen based on the cultural methods In which E. coli was detected in 95.4% (105/110) …


Protective Effect Of Cichorium Intybus ( Dandelion) Against Thiamethoxam Induced Hepatotoxicity In Chicken, Aml M. Mohammed, Magdy S. Amer, Aza E. Hassan, Ahmed Ateya, Eman S. El-Ashry Jan 2024

Protective Effect Of Cichorium Intybus ( Dandelion) Against Thiamethoxam Induced Hepatotoxicity In Chicken, Aml M. Mohammed, Magdy S. Amer, Aza E. Hassan, Ahmed Ateya, Eman S. El-Ashry

Mansoura Veterinary Medical Journal

Background : Thiamethoxam (TMX) is a dangerous neonicotinoid pesticide that induces liver damage in chickens. In this study, the toxicity of TMX in chicken was examined along with the capacity of dandelion extract to alleviate TMX toxicity. Methods: A total of 48 one-day-old, clinically healthy, non-vaccinated chicks. Chicks were divided into four groups (12 chicks per group): control (saline), TMX, TMX + Dandelion (DAN), and DAN + TMX. The treatment groups were orally administered TMX at 500 mg/kg BW and dandelion extract at 400 mg/kg BW, and the experiment was extended over 60 days. Blood samples were collected at 60th …


The Fight Against Antimicrobial Resistance: Insights And Strategies, Foram Patel Jan 2024

The Fight Against Antimicrobial Resistance: Insights And Strategies, Foram Patel

Eagles Talking About the Public’s Health

No abstract provided.


Impact Of Asl Exposure On Spoken Phonemic Discrimination In Adult Ci Users: A Functional Near-Infrared Spectroscopy Study Open Access, S. Nematova, Benjamin Zinszer, T. Morlet, G. Morini, L.-A. Petitto, K. K. Jasińska Jan 2024

Impact Of Asl Exposure On Spoken Phonemic Discrimination In Adult Ci Users: A Functional Near-Infrared Spectroscopy Study Open Access, S. Nematova, Benjamin Zinszer, T. Morlet, G. Morini, L.-A. Petitto, K. K. Jasińska

Psychology Faculty Works

We examined the impact of exposure to a signed language (American Sign Language, or ASL) at different ages on the neural systems that support spoken language phonemic discrimination in deaf individuals with cochlear implants (CIs). Deaf CI users (N = 18, age = 18–24 yrs) who were exposed to a signed language at different ages and hearing individuals (N = 18, age = 18–21 yrs) completed a phonemic discrimination task in a spoken native (English) and non-native (Hindi) language while undergoing functional near-infrared spectroscopy neuroimaging. Behaviorally, deaf CI users who received a CI early versus later in life …


Biblioguía Especial Día De La Animación 28 Octubre, Biblioteca Udit Jan 2024

Biblioguía Especial Día De La Animación 28 Octubre, Biblioteca Udit

Biblioguías

No abstract provided.


Time-Travel And Teleology: Morality, Society, And The Life Of Lucas Bishop, Justin Martin Jan 2024

Time-Travel And Teleology: Morality, Society, And The Life Of Lucas Bishop, Justin Martin

Psychology Faculty Scholarship

The paper focuses on a rarely analyzed superhero within the X-Men universe: the time-traveling mutant and law enforcement officer Lucas Bishop. Through highlighting core narrative themes consistent throughout his various depictions in comics and animation through the lens of a constructivist approach to sociomoral development (Social Cognitive Domain Theory; SCDT), the author contends that the character’s complexity and multifaceted nature potentially has implications for understanding superheroes like Bishop as subjects worthy of scholarly and pedagogical inquiry. The narrative themes examined in support of this argument pertain to (1) how different dystopian social orders or arrangements potentially inform his morally relevant …


Online Friendships And The Bird’S Nest Drawing In The Age Of The Internet, Ian Wong Jan 2024

Online Friendships And The Bird’S Nest Drawing In The Age Of The Internet, Ian Wong

Art Therapy | Master's Theses

This study was a qualitative exploration of friendships facilitated through the internet and online video games. The goal was to investigate how online friendships compare to in-person friendships in terms of quality. Three English-speaking participants who played an online video game and had an online friendship provided unique case studies describing the differences between an online and in-person friendship. The Bird Nest Drawing art assessment by Kaiser (1996; 2016) revealed themes of attachment security which helped explain the variations in the friendships. The findings of this study opened the topic of online friendships for further exploration in the field of …


Washington University Magazine, April 2024 Jan 2024

Washington University Magazine, April 2024

Washington University Magazine

No abstract provided.


Limiting Tourism To Sustainable Levels: Options For HawaiʻI, Barry D. Solomon Jan 2024

Limiting Tourism To Sustainable Levels: Options For HawaiʻI, Barry D. Solomon

Natural Resources Journal

Many popular tourist destinations across the world are experiencing overtourism, which can cause a variety of negative environmental and socio-cultural impacts. As a result, an increasing number of governments are searching for solutions to overtourism. In the United States, Hawaiʻi needs such solutions. Until recently, many legal scholars and other observers believed that restricting tourism may be unconstitutional. However, a careful examination of the United States Supreme Court’s decisions on the Dormant Commerce Clause and the interstate right to travel show that certain restrictions on tourism may be constitutionally permissible. Indeed, recent federal court rulings support state action designed to …