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2023

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Exploring Background Noise With A Large-N Infrasound Array: Waterfalls, Thunderstorms, And Earthquakes, L. T. Scamfer, J. F. Anderson Dec 2023

Exploring Background Noise With A Large-N Infrasound Array: Waterfalls, Thunderstorms, And Earthquakes, L. T. Scamfer, J. F. Anderson

Geosciences Faculty Publications and Presentations

Ambient infrasound noise contains an abundance of information that is typically overlooked due to limitations of typical infrasound arrays. To evaluate the ability of large-N infrasound arrays to identify weak signals hidden in background noise, we examine data from a 22-element array in central Idaho, USA, spanning 58 days using a standard beamforming method. Our results include nearly continuous detections of diverse weak signals from infrasonic radiators, sometimes at surprising distances. We observe infrasound from both local (8 km) and distant (195 km) waterfalls. Thunderstorms and earthquakes are also notable sources, with distant thunderstorm infrasound observed from ∼800 to 900 …


Act-Enhanced Behavior Therapy For A Hispanic Adult With Trichotillomania: A Case Report, Marissa L. Donahue, Michael P. Twohig Dec 2023

Act-Enhanced Behavior Therapy For A Hispanic Adult With Trichotillomania: A Case Report, Marissa L. Donahue, Michael P. Twohig

Psychology Faculty Publications

Trichotillomania, also known as Hair-Pulling Disorder, is characterized by recurrent pulling out of one’s hair over brief episodes or sustained periods of time and results in hair loss. ACT-enhanced behavior therapy (A-EBT) has been shown to be an effective approach in the treatment of trichotillomania by promoting psychological flexibility around hair pulling urges and teaching stimulus control and habit reversal training. However, there is limited support of A-EBT for clients with an ethnic minority identity. This case report focuses on an adult, Hispanic female client, Luna (pseudonym), who received eight sessions of A-EBT for the treatment of trichotillomania. At post-treatment, …


Effect Of Influencers On The Intention To Taste Local Food And Beverages, Yeliz Demir, Serkan Bertan Dec 2023

Effect Of Influencers On The Intention To Taste Local Food And Beverages, Yeliz Demir, Serkan Bertan

Journal of Mediterranean Tourism Research

The study aims to determine the impact of influencers promoting local food and beverages on individuals’ intention to taste local food. In this study, Instagram accounts were selected as the social media platform. The research data were obtained from Turkish Instagram users over the age of 18 by using an online survey and purposive sampling method, and usable data were obtained from 81 people. Of the participants, 56.8% stated that they follow Instagram accounts related to gastronomy, and 43.2% stated that they do not follow these social media accounts but look at the photos and videos of gastronomy accounts when …


Triumph Through Tragedy, One Student At At Time, Chanel M. Schwenck Dec 2023

Triumph Through Tragedy, One Student At At Time, Chanel M. Schwenck

Kentucky Teacher Education Journal: The Journal of the Teacher Education Division of the Kentucky Council for Exceptional Children

The EF-4 tornado that struck Mayfield, Kentucky on the evening of December 10, 2021 caused tremendous destruction to the entire community of Mayfield. Two education professors at a neighboring university sought to help students in the Mayfield Independent School District and were able to do so via funding from a KEEP mini-grant. 81 of their college students were trained in Response to Intervention (RtI) practices and provided individual and small group instruction to students in Mayfield for 2 hours a week for 17 weeks during the 2022-2023 school year. Altogether, struggling students in Mayfield received 1,377 hours of RtI instruction …


Recipe 2, A Thai Herbal Remedy In Worayokasarn Scripture, For Reducing Obesity, Pannawat Chaiyawathanananthn Dec 2023

Recipe 2, A Thai Herbal Remedy In Worayokasarn Scripture, For Reducing Obesity, Pannawat Chaiyawathanananthn

Asian Medical Journal and Alternative Medicine

Recipe 2 is a Thai herbal medical remedy for treating obesity in Worayokasarn scripture. The recipe consists of three plants i.e., Terminalia chebula Retz. (Sa-Mor-Thai) fruits, Cyperus rotundus L. (Hua-Haw-Mhoo) rhizomes, Tinospora crispa (L.) Miers ex Hook. f. & Thomson or Tinospora cordifolia (Thunb.) Miers (Bo-Ra-Pet) vines.1 The three herbal ingredients of the remedy showed anti-obese effects by reducing lipid accumulation and lipogenesis. The ethanolic extract of T. chebula fruit decreased lipogenesis in obese mice by reducing fatty acid synthase, increasing fatty acid oxidation through peroxisome proliferator-activated receptors α (PPARα) and carnitine palmitoyltransferase-1 (CPT-1).2 After 14 days of …


Nitrogen-Doped Graphite Felt On The Performance Of Aqueous Quinone-Based Redox Flow Batteries, Heng Zhang, Li-Xing Xia, Shan Jiang, Fu-Zhi Wang, Zhan-Ao Tan Dec 2023

Nitrogen-Doped Graphite Felt On The Performance Of Aqueous Quinone-Based Redox Flow Batteries, Heng Zhang, Li-Xing Xia, Shan Jiang, Fu-Zhi Wang, Zhan-Ao Tan

Journal of Electrochemistry

Modification of electrode is vitally important for achieving high energy efficiency in aqueous quinone-based redox flow batteries (AQRFBs). The modification of graphite felt (GF) was carried out by means of urea hydrothermal reaction, and simultaneously, the effects of hydrothermal reaction time on the functional groups and surface structure of nitrogen-doped graphite felt were studied. The surface morphology and defect, element content and surface chemical state of the modified electrode were characterized by scanning electron microscopy (SEM), Brunauer-Emmett-Teller (BET) test, Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS). The electrochemical performance of the modified electrodes was evaluated by cyclic voltammetry, electrochemical impedance …


Electrochemical Performance Of Porous Ceramic Supported Tubular Solid Oxide Electrolysis Cell, Heng-Ji Wang, Wen-Guo Chen, Zhou-Yi Quan, Kai Zhao, Yi-Fei Sun, Min Chen, Ogenko Volodymyr Dec 2023

Electrochemical Performance Of Porous Ceramic Supported Tubular Solid Oxide Electrolysis Cell, Heng-Ji Wang, Wen-Guo Chen, Zhou-Yi Quan, Kai Zhao, Yi-Fei Sun, Min Chen, Ogenko Volodymyr

Journal of Electrochemistry

Solid oxide electrolysis cell (SOEC) is an efficient and clean energy conversion technology that can utilize electricity obtained from renewable resources, such as solar, wind, and geothermal energy to electrolyze water and produce hydrogen. The conversion of abundant intermittent energy to hydrogen energy would facilitate the efficient utilization of energy resources. SOEC is an all-ceramic electrochemical cell that operates in the intermediate to high temperature range of 500–750 ℃. Compared with traditional low temperature electrolysis technology (e.g., alkaline or proton exchange membrane cells operating at ~100 ℃), the high-temperature SOEC can increase the electrolysis efficiency from 80% to ~100%, providing …


Intelligent Control Based On Bp Artificial Neural Network For Electrochemical Nitrate Removal, Xin-Wan Zhang, Guang-Yuan Meng, Li-Qiang Fang, Ding-Ming Chang, Tong Li, Jin-Wen Hu, Peng Chen, Yong-Di Liu, Le-Hua Zhang Dec 2023

Intelligent Control Based On Bp Artificial Neural Network For Electrochemical Nitrate Removal, Xin-Wan Zhang, Guang-Yuan Meng, Li-Qiang Fang, Ding-Ming Chang, Tong Li, Jin-Wen Hu, Peng Chen, Yong-Di Liu, Le-Hua Zhang

Journal of Electrochemistry

Achieving effective control of parameters in the process of nitrate wastewater treatment is critical to electrochemical water treatment. The powerful nonlinear mapping ability, self-adaptation and self-learning ability of neural network technology can optimize the electrochemical processing. However, there are few researches in this direction. Hence, based on the test data of the electrochemical reduction of nitrate, an electrochemical prediction model was established by using the BP neural network algorithm. Considering the correlation of various parameters in the electrochemical process, the reaction time, initial nitrate nitrogen concentration, pH and current density were determined as the input layer of the BP neural …


The Effect Of Destination Image Between Place Attachment And Cuisine Brand Value: Beyağaç Culture And Tarhana Festival, Tuğçe Koştur, Serkan Bertan Dec 2023

The Effect Of Destination Image Between Place Attachment And Cuisine Brand Value: Beyağaç Culture And Tarhana Festival, Tuğçe Koştur, Serkan Bertan

Journal of Mediterranean Tourism Research

While meeting the food and beverage needs of the visitors participating in the festival, highlighting the elements of local cuisine is an important tool in promoting the culinary culture. The aim of this research is to measure the mediating effect of destination image on cuisine brand value and place attachment. Data were collected from visitors who participated in the Beyağaç Culture and Tarhana Festival with a questionnaire. The obtained data were analyzed with partial least squares structural equation modeling. In this context, according to the results of the research, it has been determined that the destination image has a mediating …


Genital Tract Infections, The Vaginal Microbiome And Gestational Age At Birth Among Pregnant Women In South Africa: A Cohort Study Protocol, Ranjana M.S. Gigi, Mandisa M. Mdingi, Hyunsul Jung, Shantelle Claassen-Weitz, Lukas Bütikofer, Jeffrey D. Klausner, Christina A. Muzny, Christopher M. Taylor, Janneke H.H.M. Van De Wijgert, Remco P.H. Peters, Nicola Low Dec 2023

Genital Tract Infections, The Vaginal Microbiome And Gestational Age At Birth Among Pregnant Women In South Africa: A Cohort Study Protocol, Ranjana M.S. Gigi, Mandisa M. Mdingi, Hyunsul Jung, Shantelle Claassen-Weitz, Lukas Bütikofer, Jeffrey D. Klausner, Christina A. Muzny, Christopher M. Taylor, Janneke H.H.M. Van De Wijgert, Remco P.H. Peters, Nicola Low

School of Medicine Faculty Publications

Introduction Preterm birth complications are the most common cause of death in children under 5 years. The presence of multiple microorganisms and genital tract inflammation could be the common mechanism driving early onset of labour. South Africa has high levels of preterm birth, genital tract infections and HIV infection among pregnant women. We plan to investigate associations between the presence of multiple lower genital tract microorganisms in pregnancy and gestational age at birth. Methods and analysis This cohort study enrols around 600 pregnant women at one public healthcare facility in East London, South Africa. Eligible women are ≥18 years and …


Alumni Association Hires Fundraiser, Assistant Director, Staff Report Dec 2023

Alumni Association Hires Fundraiser, Assistant Director, Staff Report

University of Mississippi News

OXFORD, Miss. – Two Ole Miss Alumni Association staff members have accepted new roles within the organization.


Finding An Answer In Time: Assessing Change In Needs Scores On Time To Recidivism Among Justice-Involved Youth, Amber Krushas, Zachary Hamilton, Alex Kigerl, Xiaohan Mei Dec 2023

Finding An Answer In Time: Assessing Change In Needs Scores On Time To Recidivism Among Justice-Involved Youth, Amber Krushas, Zachary Hamilton, Alex Kigerl, Xiaohan Mei

Criminology and Criminal Justice Faculty Publications

Purpose

While risk instruments are consistently used to aid classification and supervision decisions, needs assessments guide intervention efforts for individuals under supervision. At the core of the Risk-Needs-Responsivity (RNR) model and the General Personality and Cognitive Social Learning (GPCSL) theory, dynamic needs scoring allows agencies to identify change in needs over time. Yet, few studies have assessed the potential impact of changes among needs items. To overcome this limitation, the current study assesses how needs score change may influence recidivism propensity among youth.

Methods

Using multi-level frailty models, the current study examines how changes in youth needs assessment scores influence …


Pre-Service Teachers’ Experiences With Multi-Tiered Systems Of Support: Universal Screening & Intervention Planning, Alexandra J. Taylor, Tommy Wells, Amy Lein Dec 2023

Pre-Service Teachers’ Experiences With Multi-Tiered Systems Of Support: Universal Screening & Intervention Planning, Alexandra J. Taylor, Tommy Wells, Amy Lein

Kentucky Teacher Education Journal: The Journal of the Teacher Education Division of the Kentucky Council for Exceptional Children

Assessment plays a key role in the multi-tiered system of support (MTSS) model. Universal screening is an assessment component embedded into MTSS, specifically within the response to intervention framework. The process of administering, scoring, and analyzing data from a universal screener is an essential skill that pre-service teachers need to gain in their educator preparation programs. In this qualitative, case study approach, we examined the ways an experimental learning project in implementing universal screeners impact pre-service teachers’ beliefs and practices for Tier 1 of MTSS. The project was provided to pre-service teachers to give them familiarization with the implementation of …


6 Strategies To Increase Your Classroom And School’S Culture And Climate, Stacey Keown-Murray, Rob Carroll, Kristi Livingston Dec 2023

6 Strategies To Increase Your Classroom And School’S Culture And Climate, Stacey Keown-Murray, Rob Carroll, Kristi Livingston

Kentucky Teacher Education Journal: The Journal of the Teacher Education Division of the Kentucky Council for Exceptional Children

Creating a positive culture and climate in the classroom and school environment is crucial for fostering student engagement, well-being, and academic success. This article presents six effective strategies that educators can implement to enhance the culture and climate within their classrooms and schools. The strategies focus on promoting a sense of belonging, establishing clear expectations, fostering positive relationships, celebrating diversity, empowering student voice, and encouraging collaboration and teamwork. By implementing these strategies, educators can cultivate a supportive and inclusive environment that nurtures the holistic development of students and promotes a positive learning experience. The abstract provides a concise overview of …


Who's Publishing What: The Weight We Carry, Erma Bombeck Writers' Workshop Dec 2023

Who's Publishing What: The Weight We Carry, Erma Bombeck Writers' Workshop

Erma Bombeck Writers' Workshop Blog

Christina Consolino's newest novel, The Weight We Carry, "reminds us of the fine line between reliance and independence, tending and mothering, and love and obligation."


Melancholic Cries From Border: A Study Of Northern Khmers’ Songs About Mourning The Late King Rama Ix As Their Poetry Of Sorrow, Direk Hongthong Dec 2023

Melancholic Cries From Border: A Study Of Northern Khmers’ Songs About Mourning The Late King Rama Ix As Their Poetry Of Sorrow, Direk Hongthong

Journal of Letters

After King Rama IX passed away in 2016, many groups of Thai citizens, including Northern Khmers in the southern part of Northeastern Thailand, produced literary texts for mourning the late king. This research paper aimed at examining 29 pieces of Northern Khmers’ lyrics composed for mourning the late King Rama IX and posted on www.youtube.com from October 16th, 2016 to October 14th, 2017. This study, which applied Chatuporn Misakul’s research on Thai poetry of sorrow (2013) as guideline, revealed that the data, which were Northern Khmers’ new group of literary works, were presented in 5 main aspects: (1) mourning the …


Maternal Western Diet Programs Cardiometabolic Dysfunction And Hypothalamic Inflammation Via Epigenetic Mechanisms Predominantly In The Male Offspring, Mona Elgazzaz, Clara Berdasco, Jone Garai, Melody Baddoo, Shiping Lu, Hisham Daoud, Jovanny Zabaleta, Franck Mauvais-Jarvis, Eric Lazartigues Dec 2023

Maternal Western Diet Programs Cardiometabolic Dysfunction And Hypothalamic Inflammation Via Epigenetic Mechanisms Predominantly In The Male Offspring, Mona Elgazzaz, Clara Berdasco, Jone Garai, Melody Baddoo, Shiping Lu, Hisham Daoud, Jovanny Zabaleta, Franck Mauvais-Jarvis, Eric Lazartigues

School of Medicine Faculty Publications

Objective; Maternal exposure during pregnancy is a strong determinant of offspring health outcomes. Such exposure induces changes in the offspring epigenome resulting in gene expression and functional changes. In this study, we investigated the effect of maternal Western hypercaloric diet (HCD) programming during the perinatal period on neuronal plasticity and cardiometabolic health in adult offspring. Methods; C57BL/6J dams were fed HCD for 1 month prior to mating with regular diet (RD) sires and kept on the same diet throughout pregnancy and lactation. At weaning, offspring were maintained on either HCD or RD for 3 months resulting in 4 treatment groups …


School Environment As Barrier To Effective Academic Performance Among Students With Physical Disabilities In Ilorin Metropolis, Florence Bosede Famolu Dec 2023

School Environment As Barrier To Effective Academic Performance Among Students With Physical Disabilities In Ilorin Metropolis, Florence Bosede Famolu

Jurnal Kajian Bimbingan dan Konseling

Insufficient infrastructural facilities make it difficult for a large number of students with visual and mobility impairment to walk around the campus and attend lectures. Also, fewer than ideal library facilities decrease the amount of study resources that are available to these students. This study investigated the school environment as barrier to effective academic performance among students with physical disabilities in the Ilorin metropolis, Kwara State. The descriptive survey of a correlational type was implemented using purposive sampling for this study. A purposive sampling technique was used to select 98 students in the Ilorin metropolis with physical disabilities, and the …


Measuring The Difficulties Of Early Adulthood: The Development Of The Quarter Life Crisis Scale, Muslim Afandi, Nail Hidaya Afandi, Syed Agung Afandi, Rizki Erdayani Dec 2023

Measuring The Difficulties Of Early Adulthood: The Development Of The Quarter Life Crisis Scale, Muslim Afandi, Nail Hidaya Afandi, Syed Agung Afandi, Rizki Erdayani

Jurnal Kajian Bimbingan dan Konseling

This study was conducted to develop a quarter-life crisis scale that can be used to measure the quarter-life crisis of early adulthood in Indonesia. Although it has begun to become a concern for researchers in Indonesia, the development of the quarter-life crisis scale has never been created. Some researchers have adapted the constructs developed by foreign researchers, which are not necessarily suitable for applicated in Indonesia. The development of this scale goes through 5 stages: conceptualization of the test; test construction; test trial; item analysis; and test revision. The test trial was filled by 181 early adults in Indonesia from …


‘Gantt Chart’ For Scheduling A Scientific Project, Bukkambudhi V. Murlimanju, Krishnananda R.V. Prabhu Dec 2023

‘Gantt Chart’ For Scheduling A Scientific Project, Bukkambudhi V. Murlimanju, Krishnananda R.V. Prabhu

Manipal Journal of Medical Sciences

NA


Cavernous Haemangioma Of Middle Turbinate – A Case Report, Deviprasad Dosemane, Meera Niranjan Khadilkar, Cheryl S. Philipose, Vinuta Patil Dec 2023

Cavernous Haemangioma Of Middle Turbinate – A Case Report, Deviprasad Dosemane, Meera Niranjan Khadilkar, Cheryl S. Philipose, Vinuta Patil

Manipal Journal of Medical Sciences

Cavernous haemangiomas are benign slow growing vascular tumours. Those arising out of the nasal cavity have a prevalence of 20% of all benign nasal cavity tumours, of which only 1% are intraosseous. Our case is of a 60-year-old hypertensive female patient who presented with complaints of recurrent epistaxis, which was later found to be due the presence of a vascular tumor arising from the middle turbinate. Cavernous haemangioma of the middle turbinate is rare. Symptoms like nasal blockage, epistaxis, and headache warrant suspicion. MRI aids diagnosis, but histopathology confirms its benign nature.


Congenital Cystic Adenomatoid Malformation Type-1 In Female Appropriate For Gestational Age Infant, Rishit Anand, Niharika Srivastava, Santosh Rai, Kochikar Anand Pai Dec 2023

Congenital Cystic Adenomatoid Malformation Type-1 In Female Appropriate For Gestational Age Infant, Rishit Anand, Niharika Srivastava, Santosh Rai, Kochikar Anand Pai

Manipal Journal of Medical Sciences

Congenital Cystic Adenomatoid Malformation Type-I corresponds to respiratory distress and is a congenital lung condition linked to aberrant lung development brought on by lung tissue overgrowth that creates cysts in the lung lobes.

A 36-year-old female patient with uterine gestation of 24 weeks reported with thin-walled cystic lesion in left thoracic cavity displacing the cardia to right side which could have likely been CCAM Type-1. At 20th day of the delivery, CECT Chest was performed which reported well-defined round thin-walled unilocular cystic lesion in the apico posterior segment of left upper lobe with air-fluid level and compensatory hypertrophy of left …


Information Behavior And Hiv/Aids/Sti Awareness Among Bangladeshi Female Sex Workers: Do Informational Programs Help?, Nafiz Z. Shuva, Radia Taisir, Parvez Sazzad Mallick Dec 2023

Information Behavior And Hiv/Aids/Sti Awareness Among Bangladeshi Female Sex Workers: Do Informational Programs Help?, Nafiz Z. Shuva, Radia Taisir, Parvez Sazzad Mallick

Publications and Research

Using de Certeau's concepts of “tactics” and “strategies,” this study explores the everyday information seeking behavior of female sex workers (FSWs) in Bangladesh. This study also examined the effectiveness of informational programs on HIV/AIDS and STI in empowering FSWs to negotiate condom use during sex. A mixed method research design was employed in this study, which included face-to-face surveys with 116 female sex workers (FSWs) and four focus group discussions (FGDs) with 23 street based FSWs. The study finds that Bangladeshi female sex workers use “tactics” in meeting their information needs. They reported rarely using formal information sources such as …


Optimal Design Of Heat Exchangers To Enhance Thermal Performance, Nanami Mezaki Dec 2023

Optimal Design Of Heat Exchangers To Enhance Thermal Performance, Nanami Mezaki

Mechanical Engineering and Materials Science Independent Study

Heat transfer is a key aspect of devices and industrial processes for maintaining their functionality and achieving better product quality. Heat exchangers of different types and sizes are used to transfer heat between a source and a working fluid to maintain the desirable working temperatures. Due to the space requirements of devices, there is a need for efficient heat exchangers with less size and less weight. Gyroid structure is a type of Triply Periodic Minimal Surface structures that define an internal volume that maximizes surface area and strength while minimizing mass. The hypothesis is that gyroid structures are useful …


Cover And Contents Dec 2023

Cover And Contents

Turkish Journal of Biology

No abstract provided.


Svm-Do: Identification Of Tumor-Discriminating Mrna Signatures Via Support Vectormachines Supported By Disease Ontology, Mustafa Erhan Özer, Pemra Özbek Sarica, Kazim Yalçin Arğa Dec 2023

Svm-Do: Identification Of Tumor-Discriminating Mrna Signatures Via Support Vectormachines Supported By Disease Ontology, Mustafa Erhan Özer, Pemra Özbek Sarica, Kazim Yalçin Arğa

Turkish Journal of Biology

Background/aim: The complicated nature of tumor formation makes it difficult to identify discriminatory genes. Recently, transcriptome-based supervised classification methods using support vector machines (SVMs) have become popular in this field. However, the inclusion of less significant variables in the construction of classification models can lead to misclassification. To improve model performance, feature selection methods such as enrichment analysis can be used to extract useful variable sets. The detection of genes that can discriminate between normal and tumor samples in the association of cancer and disease remains an area of limited information. We therefore aimed to discover novel and practical sets …


Deep Learning In Bioinformatics, Malik Yousef, Jens Allmer Dec 2023

Deep Learning In Bioinformatics, Malik Yousef, Jens Allmer

Turkish Journal of Biology

Deep learning is a powerful machine learning technique that can learn from large amounts of data using multiple layers of artificial neural networks. This paper reviews some applications of deep learning in bioinformatics, a field that deals with analyzing and interpreting biological data. We first introduce the basic concepts of deep learning and then survey the recent advances and challenges of applying deep learning to various bioinformatics problems, such as genome sequencing, gene expression analysis, protein structure prediction, drug discovery, and disease diagnosis. We also discuss future directions and opportunities for deep learning in bioinformatics. We aim to provide an …


Compcorona: A Web Application For Comparative Transcriptome Analyses Ofcoronaviruses Reveals Sars-Cov-2-Specific Host Response, Rana Sali̇hoğlu, Fati̇h Saraçoğlu, Mustafa Si̇bai̇, Tali̇p Zengi̇n, Başak Abak Masud, Onur Karasoy, Tuğba Önal Süzek Dec 2023

Compcorona: A Web Application For Comparative Transcriptome Analyses Ofcoronaviruses Reveals Sars-Cov-2-Specific Host Response, Rana Sali̇hoğlu, Fati̇h Saraçoğlu, Mustafa Si̇bai̇, Tali̇p Zengi̇n, Başak Abak Masud, Onur Karasoy, Tuğba Önal Süzek

Turkish Journal of Biology

Background/aim: Understanding the mechanism of host transcriptomic response to infection by the SARS-CoV-2 virus is crucial, especially for patients suffering from long-term effects of COVID-19, such as long COVID or pericarditis inflammation, potentially linked to side effects of the SARS-CoV-2 spike proteins. We conducted comprehensive transcriptome and enrichment analyses on lung and peripheral blood mononuclear cells (PBMCs) infected with SARS-CoV-2, as well as on SARS-CoV and MERS-CoV, to uncover shared pathways and elucidate their common disease progression and viral replication mechanisms. Materials and methods: We developed CompCorona, the first interactive online tool for visualizing gene response variance among the family …


Stemnesscore: An R Package To Estimate The Stemness Of Glioma Cancer Cells At Single-Cell Resolution, Necla Koçhan, Yavuz Oktay, Gökhan Karakülah Dec 2023

Stemnesscore: An R Package To Estimate The Stemness Of Glioma Cancer Cells At Single-Cell Resolution, Necla Koçhan, Yavuz Oktay, Gökhan Karakülah

Turkish Journal of Biology

Background/aim: Glioblastoma is the most heterogeneous and the most difficult-to-treat type of brain tumor and one of the deadliest among all cancers. The high plasticity of glioma cancer stem cells and the resistance they develop against multiple modalities of therapy, along with their high heterogeneity, are the main challenges faced during treatment of glioblastoma. Therefore, a better understanding of the stemness characteristics of glioblastoma cells is needed. With the development of various single-cell technologies and increasing applications of machine learning, indices based on transcriptomic and/or epigenomic data have been developed to quantitatively measure cellular states and stemness. In this study, …


Classification Of Colon Cancer Patients Into Consensus Molecular Subtypes Using Support Vector Machines, Necla Koçhan, Baris Emre Dayanc Dec 2023

Classification Of Colon Cancer Patients Into Consensus Molecular Subtypes Using Support Vector Machines, Necla Koçhan, Baris Emre Dayanc

Turkish Journal of Biology

Background/aim: The molecular heterogeneity of colon cancer has made classification of tumors a requirement for effective treatment. One of the approaches for molecular subtyping of colon cancer patients is the Consensus Molecular Subtypes (CMS) developed by the Colorectal Cancer Subtyping Consortium (CRCSC). CMS-specific RNA-Seq dependent classification approaches are recent with relatively low sensitivity and specificity. In this study, we aimed to classify patients into CMS groups using RNA-seq profiles. Materials and methods: We first identified subtype specific and survival associated genes using Fuzzy C-Means (FCM) algorithm and log-rank test. Then we classified patients using Support Vector Machines with Backward Elimination …