Digital Commons Network^™

Genotype, Oxidase Status, And Preceding Infection Or Autoinflammation Do Not Affect Allogeneic Hct Outcomes For Cgd, Jennifer W Leiding, Danielle E Arnold, Suhag Parikh, Brent Logan, Rebecca A Marsh, Linda M Griffith, Ruizhe Wu, Sharon Kidd, Kanwaldeep Mallhi, Deepak Chellapandian, Stephanie J Si Lim, Eyal Grunebaum, E Liana Falcone, Luis Murguia-Favela, Debbi Grossman, Vinod K Prasad, Jennifer R Heimall, Fabien Touzot, Lauri M Burroughs, Jack Bleesing, Neena Kapoor, Jasmeen Dara, Olatundun Williams, Malika Kapadia, Benjamin R Oshrine, Jeffrey J Bednarski, Ahmad Rayes, Hey Chong, Geoffrey D E Cuvelier, Lisa R Forbes Satter, Caridad Martinez, Mark T Vander Lugt, Lolie C Yu, Shanmuganathan Chandrakasan, Avni Joshi, Susan E Prockop, Blachy J Dávila Saldaña, Victor Aquino, Larisa A Broglie, Christen L Ebens, Lisa M Madden, Kenneth Desantes, Jordan Milner, Hemalatha G Rangarajan, Ami J Shah, Alfred P Gillio, Alan P Knutsen, Holly K Miller, Theodore B Moore, Pamela Graham, Andrea Bauchat, Nancy J Bunin, Pierre Teira, Aleksandra Petrovic, Sharat Chandra, Hisham Abdel-Azim, Morna J Dorsey, Olga Birbrayer, Morton J Cowan, Christopher C Dvorak, Elie Haddad, Donald B Kohn, Luigi D Notarangelo, Sung-Yun Pai, Jennifer M Puck, Michael A Pulsipher, Troy R Torgerson, Harry L Malech, Elizabeth M Kang

Faculty, Staff and Students Publications

Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by life-threatening infections and inflammatory conditions. Hematopoietic cell transplantation (HCT) is the definitive treatment for CGD, but questions remain regarding patient selection and impact of active disease on transplant outcomes. We performed a multi-institutional retrospective and prospective study of 391 patients with CGD treated either conventionally (non-HCT) enrolled from 2004 to 2018 or with HCT from 1996 to 2018. Median follow-up after HCT was 3.7 years with a 3-year overall survival of 82% and event-free survival of 69%. In a multivariate analysis, a Lansky/Karnofsky score < 90 and use of HLA-mismatched donors negatively affected survival. Age, genotype, and oxidase status did not affect outcomes. Before HCT, patients had higher infection density, higher frequency of noninfectious lung and liver diseases, and more steroid use than conventionally treated patients; however, these issues did not adversely affect HCT survival. Presence of pre-HCT inflammatory conditions was associated with chronic graft-versus-host disease. Graft failure or receipt of a second HCT occurred in 17.6% of the patients and was associated with melphalan-based conditioning and/or early mixed chimerism. At 3 to 5 years after HCT, patients had improved growth and nutrition, resolved infections and inflammatory disease, and lower rates of antimicrobial prophylaxis or corticosteroid use compared with both their baseline and those of conventionally treated patients. HCT leads to durable resolution of CGD symptoms and lowers the burden of the disease. Patients with active infection or inflammation are candidates for transplants; HCT should be considered before the development of comorbidities that could affect performance status. This trial was registered at www.clinicaltrials.gov as #NCT02082353.

Skills To Support Mental Health In Uncertain Times, Part 3: Being Engaged, Heather H. Kelley, Rachel Byers, Ty Aller, Timothy Keady

All Current Publications

This fact sheet is the third in a series of three about skills to improve mental health. It addresses how being engaged involves aligning your actions with your values (what you care about). This can be done by setting goals and committing to following through with the goals.

Does Patella Lowering As Part Of Multilevel Surgery Improve Knee Kinematics In Children With Cerebral Palsy And Crouch Gait? A Meta-Analysis Of Comparative Studies, María Galán-Olleros, Sergio Lerma-Lara, Beltran Torres-Izquierdo, Ana Ramírez-Barragán, Rosa M Egea-Gámez, Pooya Hosseinzadeh, Ignacio Martínez-Caballero

2020-Current year OA Pubs

PURPOSE: To evaluate differences in knee kinematic outcomes of patellar-lowering surgery, specifically patellar tendon advancement or patellar tendon shortening, compared with no-patellar-lowering surgery in multilevel surgery for children with cerebral palsy and crouch gait.

METHODS: Four databases were searched to retrieve studies published from inception until 2023. Three reviewers independently screened for studies with observational or randomized control designs, comparing two groups of patients with cerebral palsy and crouch gait who underwent multilevel surgery (with patellar-lowering surgery versus no-patellar-lowering surgery), where various gait analysis outcomes were reported (CRD42023450692). The risk of bias was assessed with the Risk Of Bias In …

A Personal Tribute To Professor Ashok Midha, Larry L. Howell

Faculty Publications

When I received the news that Professor Ashok Midha had passed away, I was grieved by the unexpected news. But I also felt another emotion: gratitude for having known him. I am grateful for him, for the opportunity I had to learn from him, and for the influence he has had on my life and career. I wanted to honor his memory in some way. This document is in response to that desire.

Some of my thoughts at his passing are summarized in the first chapter and the conclusion. The other writing is taken from a draft of my personal …

Assuring Netlist-To-Bitstream Equivalence Using Physical Netlist Generation And Structural Comparison, Reilly Mckendrick, Jeffrey Goeders, Keenan Faulkner

Faculty Publications

Hardware netlists are generally converted into a bitstream and loaded onto an FPGA board through vendor-provided tools. Due to the proprietary nature of these tools, it is up to the designer to trust the validity of the design’s conversion to bitstream. However, motivated attackers may alter the CAD tools’ integrity or manipulate the stored bitstream with the intent to disrupt the functionality of the design. This paper proposes a new method to prove functional equivalence between a synthesized netlist, and the produced FPGA bitstream. The novel approach is comprised of two phases: first, we show how we can utilize implementation …

First-Generation Cephalosporins For Treatment Of Acute Hematogenous Osteomyelitis In Children: A Study Of Efficacy And Adverse Effects, Lisa Hiskey, Hiba Saifuddin, Emily R. Levy, Roland Hentz, Nipunie S. Rajapakse, Laura M. Dinnes, Elizabeth H. Ristagno

School of Medicine Faculty Publications

BACKGROUND: Acute hematogenous osteomyelitis (AHO) is a relatively infrequent but significant infection in pediatric patients. As is the most common cause of AHO, intravenous and oral first-generation cephalosporins are common therapies. Cephalexin is a commonly prescribed oral therapy for pediatric AHO, although it requires frequent dosing that may affect adherence. Cefadroxil is a comparable oral first-generation cephalosporin with a more desirable dosing schedule. METHODS: We reviewed pediatric patients admitted to Mayo Clinic between March 2002 and September 2020 for management of AHO who received treatment with a first-generation cephalosporin. We reviewed timing of oral therapy transition, therapy-associated adverse effects, and …

"Suited To The Wants Of The Country": Historical Ceramics From The Fort Vancouver Sutler's Store, Vancouver, Washington, Kaitlyn Nicole Hosken

Dissertations and Theses

For much of the early 19th century, the British Hudson's Bay Company (HBC) dominated commercial activity throughout the Pacific Northwest. Following development of the Oregon Trail in the 1840s and 1850s, however, the HBC saw increasing social and economic competition from American settlers. This research examines nationalist attitudes evident during the transition to the American colonial era and effects on the consumption of commercial goods. Analyses compare archaeological ceramics from two retail sites located in what is now Vancouver, Washington: an 1850s American sutler's store and the HBC Sale Shop. Additional comparison is made with a contemporaneous U.S. Army Officers' …

A Pairing-Free Provable Secure And Efficient Identity-Based Identification Scheme With Anonymity, J. J. Chin, R. Kannan, V. T. Goh, S. C. Yip

School of Engineering, Computing and Mathematics

In this paper, we propose a Blind Identity-Based Identification (Blind IBI) scheme based on the Guillou-Quisquater (GQ) scheme. Our proposed scheme combines the benefits of traditional Identity-Based Identification (IBI) schemes that can authenticate a user’s identity without rely ing on a trusted third party with the Blind Signature (BS) scheme that provides anonymity. As a result, the proposed scheme assures absolute user privacy during the authentication process. It does not rely on a third party, yet the verifier can still be assured of the user’s identity with out the user actually revealing it. In our work, we show that the …

Why Do People Hate Other Groups? The Role Of Perceived Threat As Mediator The Effect Of Group Identification Toward Group Based Hatred, Yuni Nurhamida, Hamdi Muluk, Mirra Noor Milla

Makara Human Behavior Studies in Asia

This study aimed to investigate the formation of group-based hatred in the context of latent conflict, as previous studies have predominantly explored the consequences of hatred in intractable conflicts. Group identification was hypothesized to lead to hatred of another group through perceived threat as a mediator, with the types of threat formulated from historical conflict narratives. The research context was the latent Muslim-PKI conflict in Indonesia. Realistic feelings of threat are formulated based on the narrative that the PKI (Indonesian Communist Party) is perceived to be resurging and trying to change the foundation of the state into communism. Symbolic threat …

Effect Of Different Levels Of Postbiotic And Phytobiotic Combination On Growth Performance, Economic Production, And Immune Response Of Broiler Chickens, Jamil Mobarak Mahmoud Doski, Karwan Yaseen Kareem

Polytechnic Journal

A total of two hundred and eighty eight day old unsexed chicks from a Ross 308 cross were randomly assigned to eight treatment and four replicates and each replicator had twelve birds. The experimental groups includes, N-control= negative control (basal diet), P-control = basal diet + 0.01% Doxin200 (positive control) (w/w), 0.1% Pos+Phy = basal diet + 0.05% thyme oil (v/w) + 0.05% postbiotic, 0.2% Pos+Phy = basal diet + 0.1% thyme oil (v/w) + 0.1% postbiotic, 0.3% Pos+Phy = basal diet + basal diet + 0.15% thyme oil (v/w) + 0.15% postbiotic, and 0.4% Pos+Phy = basal diet + …

Utilization Of Semiconductor Nanocrystals In Cancer Diagnose And Treatment, Yasir Q. Almajidi, Ahmed A. Albadri, Mazen M. Jwaid, Yaseen T. Khalaf

Maaen Journal for Medical Sciences

In contemporary times, nanotechnology has emerged as a notably sophisticated technological discipline. It possesses an interdisciplinary and multidisciplinary nature, spanning a wide array of domains including medical science, engineering, biology, physics, materials science, and chemistry. Utilization of nanotechnology offers a significant advantage by enabling precise manipulation and control of properties to effectively address specific challenges in various applications. In the fields of science and biomedicine, there has been extensive exploration into the use of functional nanomaterials, emerging as rapidly advancing and captivating areas of research. Diverse types of nanomaterials, including silicon nanowires, quantum dots, carbon nanotubes, and gold/silver nanoparticles, which …

Our Community Chimes In, Corinne Bishop

Journal of Graduate Librarianship

Welcome! The Journal of Graduate Librarianship’s Practitioner Panel allows us to hear directly from the graduate librarian community via social media, where we regularly post questions and invite your comments on practical issues relating to graduate librarianship. To join the conversation and share your comments about community topics, please follow us on Facebook, Instagram, Threads, or X (formerly Twitter)—or keep an eye on the JGL website, where we also post all Practitioner Panel questions.

Hosting An International Graduate Student Orientation, Liza Weisbrod, Juliet T. Rumble, Adelia Grabowsky, Isabel Altamirano, Emily Sahib

Journal of Graduate Librarianship

In Fall 2022, Auburn University Libraries faculty and staff hosted an orientation event for newly arrived international graduate students. Highlights of the event included tours of major library service points, a shared meal, and a meet and greet for graduate students and subject librarians. A key takeaway for both groups was an increased awareness of the differences that exist between U.S. academic libraries and those in other countries. The authors discuss elements of the library orientation that worked well, and address lessons learned that will be used to improve future events.

Graduate Librarian At A Small University: What I’Ve Learned So Far, Christina R. Hillman

Journal of Graduate Librarianship

Learning to be a graduate librarian is an ongoing process. Read about one librarian’s journey from early to mid-career graduate librarian. Lessons learned include understanding technology challenges faced by graduate students, what embedded librarianship looks like at the graduate level, and even when to break patron privacy.

Serving Graduate Students At A Community College Library, Daniel K. Blewett

Journal of Graduate Librarianship

Even though a community college library rarely attempts to offer the same depth of support found at a university, it can still serve the needs of local graduate students in two ways: through the library’s core collection of print and electronic resources, and through its on-site services, spaces, and librarian expertise. Graduate students need to know that these resources are available to them. The knowledge and ability of the librarian is key to supporting this patron group. This article is informed by the author’s experiences at the College of DuPage, a large comprehensive community college in northeastern Illinois.

Leveraging Existing Services To Support Evidence Synthesis Researchers Outside Of The Health Sciences, Elizabeth Kline

Journal of Graduate Librarianship

The author presents a case study for the development of an evidence synthesis service serving researchers outside of the health sciences at a large academic library. The purpose of this project was to highlight the importance of integrating existing core services and workflows that create seamless delivery of evidence synthesis support and yield quality service. The paper provides decisions that university libraries must consider as they are planning the implementation of these services.

The research-intensive nature of evidence synthesis projects provides liaison librarians with a perfect entry to deliver high-quality and relevant services, especially to graduate students and researchers. Through …

A Two-Phase Study Examining Graduate Library Student Knowledge Gains And Perceptions Of Information Literacy Modules, Holly S. Hebert, Karen V. Nourse, Kevin S. Krahenbuhl

Journal of Graduate Librarianship

This paper reports the results of a two-phase study examining the effectiveness of a set of five online learning modules in increasing student understanding of information literacy topics. The modules were deployed within the foundational class of an online Master of Library Science program. Using Qualtrics-based surveys, Phase 1 assessed 15 students for their possible knowledge gains as well as their perceptions of their experiences with the instructional content. Through a combination of statistical and qualitative analysis, the researchers found modest knowledge gains as well as positive student perceptions of their instruction. Based upon the moderate success of Phase 1, …

More Obstacles For The Graduate Student Author: Open Access Etds Trigger Plagiarism Detectors, Dede Dawson, Kate Langrell

Journal of Graduate Librarianship

Supporting graduate students as authors is one of the many services we provide at the University Library, University of Saskatchewan (USask). Graduate students often submit articles to journals based on content from their electronic theses or dissertations (ETDs). Recently, we have noticed an increase in the number of such article submissions being flagged for possible rejection on “plagiarism” or “prior publication” grounds. We suspect this may be because plagiarism detection software is increasingly being integrated into publishers’ article submission systems. This software is triggered by the existence of the student’s open access (OA) ETD in our institutional repository. This happens …

Introducing The Journal Of Graduate Librarianship, Wendy Doucette, Jill Cirasella

Journal of Graduate Librarianship

Welcome to the inaugural issue of the Journal of Graduate Librarianship, the first professional journal dedicated solely to graduate librarianship! This issue is the culmination of a two-year effort where we discovered, often the hard way, what goes into starting an academic journal.

Culturally Conscious Calculations: The Crucial Need For Cultural Competence In Elementary Mathematics, Rania Saba

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

Inclusive Primary Education In Nigeria: A Case Study Of The Global Mandate On Inclusive Education, Olusola John Ogundola

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

“Lost In Transition: The Struggles Of First-Gen, Low-Income Students In Moving From Community College To A Four-Year Institution, Victoria Cinquegrana-Rod

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

Exploring The Quality Of Experiences At Historically Black Colleges And Universities For Black Women Deans, Ciera Spady

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

Ai Tools: Empowering Learners Or Enabling Cheaters? A Policy Tightrope For Higher Education, Karen L. Teller

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

Optimizing The Pass Program: Using Improvement Science To Enhance Holistic Support For First-Year Medical Students, Suzanne Mosko

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

Evaluating A Neurodiversity Program For Student Doctors, Stephanie A.N. Levin

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

Stem's Missing Women: Why Biology's Undergraduate Pipeline Is Diverging From Career Paths, Rosemary Roberto

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

A Heuristic Inquiry Analysis On The Role Of Familismo In The Academic Acculturation Of High Achieving Latiné/X Ell High School Graduates, Shirley J. Delgado

Graduate Student and Postdoctoral Fellow Symposium

No abstract provided.

Growth And Impact: The Dual Purpose Of Leadership Development For Professionals In Middle Management Roles, Joy Karavedas

Transform

Abstract

Growth and Impact: The Dual Purpose of Leadership Development for

Professionals in Middle Management Roles

Emerging leaders are aware of the skills needed for executive leadership but may not possess the knowledge of how to develop those skills, meaning they often enter higher levels of leadership with awareness of what is needed to lead but without the actual skills to do so. More than any time in history, it is critical that those placed in leadership positions develop skills prior to being elevated. On the job leadership development is no longer a reliable option and intentionality to developmental time …

From Bedside To Boardroom: Inspiring Nurses Through Storytelling, Dr. Tricia Kassab

Transform

from bedside to boardroom: Inspiring Nurses through storytelling

The key to understanding how nurse executives use stories to lead organizations resides in a deeper examination of the type of stories told to create transformational change. The story of nurse Kassab and how she started from bedside to boardroom highlights the importance of using stories to effect changes. Nurse leaders need to connect with staff personally and forge strong relationships with teams, especially during times of stress. This article reviewed how nurse leaders set the tone of organizational cultures using a transformational leadership style to inspire, energize and influence the nursing …