Digital Commons Network^™

International Conflicts And Conflict Resolution: Periscoping The Role Of The United Nations, Chinyere Ecoma, Ejitu Ota

Khazar Journal of Humanities and Social Sciences

It is the contention of realist scholars and thinkers that states in the international system have a natural inclination or proclivity to war. This position is anchored on their belief that the world is inherently anarchic and that, therefore, it is in the interest of states in the international system to be prepared at all times to defend themselves. Relying on the historical-descriptive methodology of content analysis, this paper argues that though conflicts are inevitable in international relations, the international community has put in place certain mechanisms to avoid the occurrence of violent and destructive inter-state conflicts in order to …

Examining The Potential Of Generative Language Models For Aviation Safety Analysis: Case Study And Insights Using The Aviation Safety Reporting System (Asrs), Archana Tikayat Ray, Anirudh Prabhakara Bhat, Ryan T. White, Van Minh Nguyen, Olivia J. Pinon Fischer, Dimitri N. Marvis

Mathematics and System Engineering Faculty Publications

This research investigates the potential application of generative language models, especially ChatGPT, in aviation safety analysis as a means to enhance the efficiency of safety analyses and accelerate the time it takes to process incident reports. In particular, ChatGPT was leveraged to generate incident synopses from narratives, which were subsequently compared with ground-truth synopses from the Aviation Safety Reporting System (ASRS) dataset. The comparison was facilitated by using embeddings from Large Language Models (LLMs), with aeroBERT demonstrating the highest similarity due to its aerospace-specific fine-tuning. A positive correlation was observed between the synopsis length and its cosine similarity. In a …

Agile Methodology For The Standardization Of Engineering Requirements Using Large Language Models, Archana Tikayat Ray, Bjorn F. Cole, Olivia J. Pinonfischer, Anirudh Prabhakara Bhat, Ryan T. White, Dimitri M. Marvis

Mathematics and System Engineering Faculty Publications

The increased complexity of modern systems is calling for an integrated and comprehensive approach to system design and development and, in particular, a shift toward Model-Based Systems Engineering (MBSE) approaches for system design. The requirements that serve as the foundation for these intricate systems are still primarily expressed in Natural Language (NL), which can contain ambiguities and inconsistencies and suffer from a lack of structure that hinders their direct translation into models. The colossal developments in the field of Natural Language Processing (NLP), in general, and Large Language Models (LLMs), in particular, can serve as an enabler for the conversion …

Evaluation Of Endplate Failure In Lumbar Disc Prolapse And Their Clinical Outcome Correspondence, Mazin Mohammed Jawad

Iraqi Postgraduate Medical Journal

BACKGROUND: Endplate lesions connect in lumbar disc herniation (LDH) evolution, yet correlated clinical course scarcely comprehended. AIM OF STUDY: To examine the varieties of endplate failure (EPF) in LDH and their clinical outcome correspondence.  PATIENTS AND METHODS: A study of sixty-seven cases that have single-level LDH conducted. Magnetic Resonance Imaging (MRI) and computed tomography (CT) scans distinguish EPF. Twenty-five patients have  a laminectomy, and forty-two managed conservatively. Pursue of pain scores and clinical outcomes. RESULTS: Endplate pathology remarked in 65(97.01%), osseous endplate breakdown (Osseous failure) in 48(73.8%), and confined cartilaginous endplate lesions in 17 patients (26.2%). The group with bone …

Variation In Carapace Damage Within And Among Loggerhead Musk Turtle (Sternotherus Minor) Populations In Florida Spring-Fed Ecosystems, Joseph J. Pignatelli Iii, Katrina Campbell, Brian P. Butterfield, Gerald R. Johnston, Joseph C. Mitchell, Grover J. Brown, J. Brian Hauge, Andrew D. Walde, Eric C. Munscher

Research, Publications & Creative Work

Damage to a turtle’s shell can provide evidence of past events such as vehicle collisions, disease, predator encounters, or even a behavioural interaction between members of the same species. Documenting shell damage as part of long-term mark and recapture studies enables researchers to determine population trends, intraspecific interactions and identify potential issues within turtle populations. This paper analyses shell damage in populations of the Loggerhead Musk Turtle (Sternotherus minor) (Agassiz, 1857). We examined carapace shell damage frequency and severity in 2701 individual S. minor (1468 males and 1233 females) captured in spring-fed habitats in one state preserve and five state …

Functional Comparison Of Full-Length Palladin To Isolated Actin Binding Domain, Sharifah Albraiki, Oluwatosin Ajiboye, Rachel Sargent, Moriah R. Beck

Research, Publications & Creative Work

Palladin is an actin binding protein that is specifically upregulated in metastatic cancer cells but also colocalizes with actin stress fibers in normal cells and is critical for embryonic development as well as wound healing. Of nine isoforms present in humans, only the 90 kDa isoform of palladin, comprising three immunoglobulin (Ig) domains and one proline-rich region, is ubiquitously expressed. Previous work has established that the Ig3 domain of palladin is the minimal binding site for F-actin. In this work, we compare functions of the 90 kDa isoform of palladin to the isolated actin binding domain. To understand the mechanism …

The Borders Of Theory: Towards An Artful Ontology Of Knowing In Qualitative Research, Cristina Valencia Mazzanti

Education and Child Study: Faculty Publications

This article considers the ontology of theory as a shaping phenomenon in qualitative research by opening up its intersection with artistic dimensions of knowing and knowledge. We argue that the plurality of practices and perspectives for research hinges on what theory is understood to be. Thus, rather than approaching theory as something predefined, we draw on conceptualizations of the experience of art to articulate the being of theory as an aesthetic renewal of a shared human movement of becoming. We then illuminate theory’s potential as a multidimensional artful being by engaging with a subset of photographs of street art collected …

Exploring Academic Librarians' Perception Of Oer Through The Lens Of Technology Acceptance Model, Yingqi Tang, Hungwei Tseng

Research, Publications & Creative Work

Academic librarians' professional skills make them an ideal candidate to work with faculty in the exploration, adoption, promotion, and preservation of open educational resources (OER). This study used the technology acceptance model (TAM) to explain and predict librarians' attitudes towards OER and their intentions towards utilization in instructional design practices and teaching pedagogies. A total of 213 academic librarians participated in the mixed-methods design study. The results reveal that perceived ease of use (PEOU), perceived usefulness (PU), and self-efficacy (SE) as it relates to OER accounted for 51 % of the variance in librarians' attitude (AT) towards OER. Moreover, librarians' …

Dna Barcoding Indicates Multiple Invasions Of The Freshwater Snail Melanoides Tuberculata Sensu Lato In Florida, Lori Tolley-Jordan, Michael A. Chadwick, Jimmy K. Triplett

Research, Publications & Creative Work

Melanoides tuberculata sensu lato (Thiaridae) are polymorphic female-clonal snails of Asian and African origins that have invaded freshwaters worldwide, including those in Florida. Although the snails have been documented in Florida for at least 70 years, no studies have investigated whether the observed distribution is due to a single introduction or multiple independent invasions. Here, cytochrome oxidase I was used to measure genetic diversity within and among sites in Florida and compare genetic diversity between Florida and other regions of the world. We also examined the relationship between shell morphology and haplotype diversity to determine if shell morphs can serve …

Investigating The Viral Nature Of Neuronal Capsid Genes, Michael Manuel Long

Master's Theses

Memory formation is an essential part of everyday life. Neuronal communication is thought to be a key driver behind memory formation. There are two heavily studied methods of neuronal communication: chemical (neurotransmitter-mediated) and electrical (physically attached). When issues arise environmentally or genetically, people can experience one of many devastating memory disorders i.e. Alzheimer’s disease and other Dementias. Due to their prevalence, the treatments for disorders that hinder memory formation are a high priority for pharmaceutical companies. Currently, many of the treatments available focus on neurotransmitters or neuronal activity, and scientists are far from a cure. However, there may be an …

Characterizing The Dynamic Localization Of Cmi In Early Drosophila Development, Asra Habibullah

Master's Theses

The COMPASS-like family of lysine methyltransferases, MLR/MLX complexes, are epigenetic regulators that are essential for normal development through the methylation of the fourth lysine residue on histone 3 (H3K4), a universal epigenetic mark associated with active transcription. This family of complexes is highly conserved from yeast to mammals and the genes encoding the human MLR complexes have been associated with various developmental diseases and cancers (Dingwall and Fagan, 2019). In D. melanogaster, the enzymatic methyltransferase core of this complex is composed of two proteins: Cara Mitad (Cmi, also known as Lpt) and Trithorax-related (Trr). Although these proteins have been shown …

Parental Autonomy Support And Children’S Stem Engagement During An At-Home Tinkering Activity, Bianca Martins Aldrich

Master's Theses

Parents play an important role guiding children’s learning of science, technology, engineering, and mathematics (STEM) in informal educational contexts. In this project, we considered the ways in which parents use autonomy supportive or controlling language to encourage or discourage children's independence in problem solving, as well as their feedback to children’s ideas and behaviors. We looked at the association between autonomy support and children’s behavioral, STEM, story, and emotional engagement during an at-home tinkering and storytelling activity. Parents and their 4- to 10- year old children were observed at home via Zoom. We coded parents’ and children’s behaviors using a …

The Jewish Dancing Body: Body Image In Jewish Folk Dance, Alexa Berkowitz

Master's Theses

Throughout my life as a dancer, I often wondered if body image issues were purely found in Western concert dance (such as ballet and modern dance) and if folk dance instilled a sense of ownership over one’s body. It was apparent to me that being asked to stare at yourself in the mirror for hours on end in a ballet class, or any other dance style, forced you to see every tiny defect in your body. For me personally, this caused a lot of body dysmorphia and body image issues that I carry to this day. While some folk dance …

Making The Case For The Great Dismal Swamp National Heritage Area: A Scoping Review, Madelyn Newton, Chandler J. Berry, Bethany Arrington, Nick Wilson, Colin Mccormack, Michael Wilcox, Alexis Barmoh, Chris A. B. Zajchowski

Human Movement Studies & Special Education Faculty Publications

National Heritage Areas (NHAs) are nationally distinct landscapes that represent unique cultural, historical, and/or natural attributes significant to the legacy of the United States of America (U.S.). The Great Dismal Swamp, located in southeastern Virginia and northeastern North Carolina, is a prime candidate for NHA designation with diverse qualifications, among which was its antebellum role as a refuge for formerly enslaved people. The goal of our research, conducted in 2022 during the period of the U.S. Congressional debate on designation, was to investigate and expound upon the rationale for NHA designation of the Swamp. To do so, we used a …

Exploring Correlates Of Student Preferences For Virtual Or In-Class Learning Among Neurodiverse Adolescents Using A Single-Case Design Methodology, Taryn A. Myers, John D. Ball, Mindy Gumpert, Mary Roberts

Human Movement Studies & Special Education Faculty Publications

The purpose of the current study is to explore several correlates of adolescent students’ preferences for at-home virtual or in-class in-person learning in a single case of a school that serves students with learning differences. Correlates of interest were the Big Five personality traits (Openness to Experience, Conscientiousness, Extroversion, Agreeableness, Neuroticism) and the students’ self-reported learning engagement. Participants were recruited from a single independent school for students with neurodiversity and special learning needs, where they had high exposure to computer-/internet-assisted learning. Twenty-seven students responded to questionnaires measuring preferred learning modes, personality traits, and learning engagement. Despite teacher reports …

Let's Count The Ways We Can Utilize Technology To Improve Instructional Practices For Individuals With Autism, Heather Coleman, Annemarie L. Horn, Selena J. Layden, Christian Coogle

Human Movement Studies & Special Education Faculty Publications

To maximize instruction and learning outcomes, it is essential that educators and family members who support individuals with autism have adequate training and support required to implement evidence-based practices (EBPs) with fidelity. Research shows various coaching methods, including self-coaching and classroom-based feedback, yield positive outcomes in terms of increasing practical application and sustained use of EBPs. With the growing prevalence of autism, it is essential to find effective coaching methods that can be utilized equitably across geographic locations and learning environments. Fortunately, technology affords educators and others the opportunity to receive quality coaching and feedback without facing traditional barriers (e.g., …

The Effect Of Training Program On Autism Spectrum Quotient Scores, Hossein Nazary Sharif, Sarvin Salar, Justin Anthony Haegele

Human Movement Studies & Special Education Faculty Publications

Background: Autism Spectrum Quotient (AQ) functions as an evaluative instrument designed to assess traits associated with autism. Variances exist within the brain of individuals on the autism spectrum. Moreover, certain exercises have the potential to impact specific regions of the brain.

Aim: This study aims to investigate how the program training of this study impact Autism—Spectrum Quotient.

Materials and Methods: Forty-two children aged 7-10 years with ASD were recruited to participate in this study. These children were randomly divided into two groups: the control group (N=10, 7.80±1.35 years) and the experimental group (N=32, age: 8.16±1.16 years). The experimental group underwent …

Is This Antiracist?: An Autoethnographic Evaluation Of Professional Development, Allison Nava-Holstein

LMU Theses and Dissertations

Communities of color have been fighting for equal rights in society throughout history, resulting in the development of different social movements. In 2013, the Black Lives Matter movement was founded and protests erupted across America as Black lives were lost at the hands of law enforcement. In the summer of 2020, the protests continued, serving as a catalyst for schools to begin interrogating their practices and curricula, moving towards efforts to be pro-Black and antiracist.

Grounded in Critical Social Theory and Critical Race Theory, this autoethnographic study explores the experiences of me, a Latinx teacher in diversity, equity and inclusion …

We Do The Work. You Check The Box: Unearthing The Impact Of Racialized Stress And Trauma On Black Women Community College Educators Leading Dei Work, Brandi Renee Avila

LMU Theses and Dissertations

Since the summer of 2020, following the execution of Mr. George Floyd, many institutions of higher education established or strengthened their commitment to diversity, equity, and inclusion. In attempting to create more equitable, diverse, inclusive, and antiracist campuses to foster student success and belonging on campus, another inequity is born. Higher education institutions have failed to center the wellbeing of educators tasked with leading these efforts. This qualitative study used semistructured interviews with 10 Black women leading DEI efforts throughout the California Community College system to explore the impact of racialized stress and trauma on holistic wellbeing. Central questions guided …

(Re)Inventing Ourselves: An Asiancrit Analysis Of Counternarratives Of Asian American Women Who Lead In K–12 Public School Systems, Ella Farinas

LMU Theses and Dissertations

Despite what is known about the importance of diversity in the educator workforce, Asian American women (AAW) are not named in conversations around diversity, equity, and inclusion (DEI) in leadership. The purpose of this qualitative study was to build on the limited research on AAW in social justice leadership (SJL), explore the lived experiences of AAW educators, and elevate their voices. I sought to answer the research questions: (1) What affordances and challenges do AAW experience in choosing and enacting SJL in K–12 public school systems? (2) How do the intersectional positionalities of Asian American women affect the way they …

Badly Licked Bear Steps Up To Drive A Van Of Supplies To Navajo Nation During Covid-19

Teaching the Auntie Sewing Squad Oral History Excerpts in the Classroom

No abstract provided.

Kristina Wong Is Horrified At The Lack Of Ppe During The Covid-19 Pandemic

Teaching the Auntie Sewing Squad Oral History Excerpts in the Classroom

No abstract provided.

Adriana Camarena Makes A Supply Run To The Wildfires In Healdsburg And Petaluma During Covid-19

Teaching the Auntie Sewing Squad Oral History Excerpts in the Classroom

No abstract provided.

Theresa Hatathlie-Delmar Fundraises And Stock-Piles For Navajo Nation Prior To The National Two-Week Quarantine

Teaching the Auntie Sewing Squad Oral History Excerpts in the Classroom

No abstract provided.

Contagion, Causality, And Circumspection In A Late-Mamluk Digest Of Natural Philosophy, Joseph Leonardo Vignone

History Faculty Scholarship

Like many men born to scholarly families at the turn of the fifteenth century, ʿAbd Allāh Ibn Ayyūb al-Qādirī moved from Damascus to Cairo as a young adult to pursue a career in law. Though this legal career soon foundered, Ibn Ayyūb gained a reputation in Cairo for perfectly embodying the pietistic and professional ideals of the Islamic learned elite, or ulama. In this article, I introduce this hitherto unstudied figure of the late Mamluk era with reference to his treatise on a major scholarly debate of his day: the extent to which natures, or the elemental composition of celestial …

Tp53-Pten-Nf1 Depletion In Human Brain Organoids Produces A Glioma Phenotype In Vitro, Sanjay K Singh, Yan Wang, Ahmed Habib, Mamindla Priyadarshini, Chowdari V Kodavali, Apeng Chen, Wencai Ma, Jing Wang, N U Farrukh Hameed, Baoli Hu, Gregory N Fuller, Scott M Kulich, Nduka Amankulor, Rivka R Colen, Lincoln A Edwards, Pascal O Zinn

Faculty, Staff and Student Publications

Glioblastoma (GBM) is fatal and the study of therapeutic resistance, disease progression, and drug discovery in GBM or glioma stem cells is often hindered by limited resources. This limitation slows down progress in both drug discovery and patient survival. Here we present a genetically engineered human cerebral organoid model with a cancer-like phenotype that could provide a basis for GBM-like models. Specifically, we engineered a doxycycline-inducible vector encoding shRNAs enabling depletion of the TP53, PTEN, and NF1 tumor suppressors in human cerebral organoids. Designated as inducible short hairpin-TP53-PTEN-NF1 (ish-TPN), doxycycline treatment resulted in human cancer-like cerebral organoids that effaced the …

Minimax Estimation For Personalized Federated Learning: An Alternative Between Fedavg And Local Training?, Shuxiao Chen, Qinqing Zheng, Qi Long, Weijie J Su

Faculty, Staff and Student Publications

A widely recognized difficulty in federated learning arises from the statistical heterogeneity among clients: local datasets often originate from distinct yet not entirely unrelated probability distributions, and personalization is, therefore, necessary to achieve optimal results from each individual's perspective. In this paper, we show how the excess risks of personalized federated learning using a smooth, strongly convex loss depend on data heterogeneity from a minimax point of view, with a focus on the FedAvg algorithm (McMahan et al., 2017) and pure local training (i.e., clients solve empirical risk minimization problems on their local datasets without any communication). Our main result …

Association Of Cyclooxygenase-2 Expression With Endoplasmic Reticulum Stress And Autophagy In Triple-Negative Breast Cancer, Haechan Lee, Sungwook Jung, Gyungyub Gong, Bora Lim, Hee Jin Lee

Faculty, Staff and Student Publications

Cyclooxygenase-2 plays a role in oncogenesis and its overexpression is associated with triple-negative breast cancer. However, the mechanisms whereby cyclooxygenase-2 contribute to breast cancer are complex and not well understood. Cyclooxygenase-2 overexpression causes hypoxia, oxidative stress, and endoplasmic reticulum stress. The aim of this study is to investigate the correlations among cyclooxygenase-2 expression, endoplasmic reticulum stress-associated molecules, and autophagy-associated molecules in triple-negative breast cancer. Surgical specimens from two cohorts of triple-negative breast cancer patients without neoadjuvant systemic therapy were analyzed: cohorts 1 and 2 consisted of 218 cases from 2004 to 2006 and 221 cases from 2007 to 2009, respectively. …

Improved Outcomes With “7+3” Induction Chemotherapy For Acute Myeloid Leukemia Over The Past Four Decades: Analysis Of Swog Trial Data, Megan Othus, Guillermo Garcia-Manero, John E Godwin, James K Weick, Frederick R Appelbaum, Harry P Erba, Elihu H Estey

Faculty, Staff and Student Publications

We have previously shown that complete response (CR) rates and overall survival of patients with acute myeloid leukemia have improved since the 1980s. However, we have not previously evaluated how the length of first CR (CR1) has changed over this time period. To address this, we analyzed 1,247 patients aged 65 or younger randomized to "7+3" arms from five SWOG studies: S8600 (n=530), S9031 (n=98), S9333 (n=57), S0106 (n=301), and S1203 (n=261). We evaluated length of CR1 and survival after relapse from CR1 over the four decades that these studies represent. Both length of CR1 and survival after relapse from …

Flecainide For Conversion And Maintenance Of Sinus Rhythm After Mitral Valve Replacement In Rheumatic Atrial Fibrillation, Umesh Tripathi, Aditya Kapoor, Surendra Kumar Agarwal, Prabhat Tewari, Shantanu Pande, Bipin Chandra, Ankit Sahu, Roopali Khanna, Sudeep Kumar, Naveen Garg, Satyendra Tewari

Faculty, Staff and Student Publications

BACKGROUND: Despite successful mitral valve replacement (MVR), many patients remain in AF. Flecainide can be useful in these patients but has not been used because of underlying structural heart disease.

METHODS: We assessed oral flecainide for conversion and maintenance of SR in 25 patients of chronic rheumatic AF following MVR (age 34.4 yrs, mean AF duration: 3.6 yrs). Non-converters underwent DC cardioversion at 24 h and 4 weeks. Patients received flecainide and bb/diltiazem at discharge.

RESULTS: Single oral dose of Flecainide achieved SR in 6/25 (24%) while 19/25 achieved SR after DCC; at24 h 21/25 (84%) were in SR. With …