Digital Commons Network^™

Postsurgical Morbidity And Mortality Favorably Informs Deep Brain Stimulation For New Indications Including Schizophrenia And Schizoaffective Disorder, Judith M Gault, Patrick Hosokawa, Daniel Kramer, Elyn R Saks, Paul S Appelbaum, John A Thompson, Ann Olincy, Nicola Cascella, Akira Sawa, Wayne Goodman, Nidal Moukaddam, Sameer A Sheth, William S Anderson, Rachel A Davis

Faculty, Staff and Students Publications

BACKGROUND: Deep brain stimulation (DBS) shows promise for new indications like treatment-refractory schizophrenia in early clinical trials. In the first DBS clinical trial for treatment refractory schizophrenia, despite promising results in treating psychosis, one of the eight subjects experienced both a symptomatic hemorrhage and an infection requiring device removal. Now, ethical concerns about higher surgical risk in schizophrenia/schizoaffective disorder (SZ/SAD) are impacting clinical trial progress. However, insufficient cases preclude conclusions regarding DBS risk in SZ/SAD. Therefore, we directly compare adverse surgical outcomes for all surgical procedures between SZ/SAD and Parkinson's disease (PD) cases to infer relative surgical risk relevant to …

Multiomics, Artificial Intelligence, And Precision Medicine In Perinatology, Mohan Pammi, Nima Aghaeepour, Josef Neu

Faculty, Staff and Students Publications

Technological advances in omics evaluation, bioinformatics, and artificial intelligence have made us rethink ways to improve patient outcomes. Collective quantification and characterization of biological data including genomics, epigenomics, metabolomics, and proteomics is now feasible at low cost with rapid turnover. Significant advances in the integration methods of these multiomics data sets by machine learning promise us a holistic view of disease pathogenesis and yield biomarkers for disease diagnosis and prognosis. Using machine learning tools and algorithms, it is possible to integrate multiomics data with clinical information to develop predictive models that identify risk before the condition is clinically apparent, thus …

Unmet Needs And Coping Strategies Of Older Underserved Veterans During The Covid-19 Pandemic, Trenton M Haltom, Joyce Tiong, Tracy L Evans, Nipa Kamdar, Gala True, Mark E Kunik

Faculty, Staff and Students Publications

INTRODUCTION: The COVID-19 pandemic has had profound impacts on people with diabetes, a group with high morbidity and mortality. Factors like race, age, income, Veteran-status, and limited or interrupted resources early in the COVID-19 pandemic compounded risks for negative health outcomes. Our objective was to characterize the experiences and needs of under-resourced Veterans with type 2 diabetes during the COVID-19 pandemic.

METHODS: We conducted semi-structured qualitative interviews (March through September 2021) with U.S. military Veterans with diabetes. Transcripts were analyzed using a team-based, iterative process of summarizing and coding to identify key themes. Participants included Veterans (n = 25) who …

Δfosb Is Part Of A Homeostatic Mechanism That Protects The Epileptic Brain From Further Deterioration, Jerome Clasadonte, Tania Deprez, Gabriel S Stephens, Georges Mairet-Coello, Pierre-Yves Cortin, Maxime Boutier, Aurore Frey, Jeannie Chin, Marek Rajman

Faculty, Staff and Students Publications

Activity induced transcription factor ΔFosB plays a key role in different CNS disorders including epilepsy, Alzheimer's disease, and addiction. Recent findings suggest that ΔFosB drives cognitive deficits in epilepsy and together with the emergence of small molecule inhibitors of ΔFosB activity makes it an interesting therapeutic target. However, whether ΔFosB contributes to pathophysiology or provides protection in drug-resistant epilepsy is still unclear. In this study, ΔFosB was specifically downregulated by delivering AAV-shRNA into the hippocampus of chronically epileptic mice using the drug-resistant pilocarpine model of mesial temporal epilepsy (mTLE). Immunohistochemistry analyses showed that prolonged downregulation of ΔFosB led to exacerbation …

Peer Response And Assistance To Suicidal Thoughts And Behavior In University Students, Lindsey Katherine Hunter

Murray State Theses and Dissertations

Suicide represents the second leading cause of death in adolescents and young adults (CDC, 2022). Many interventions employed on college campus focus on peer support which has been previously related to reductions in suicidal thoughts and behaviors (STB, e.g., suicidal ideation, suicidal plan, suicide attempts), but students may not have the experience needed to increase confidence or knowledge in providing support (Hirsch & Barton, 2011; King et al., 2008). Further, previous research has identified factors including exposure to STB, direct engagement in STB, knowledge, and stigma regarding suicide which have had mixed impact on confidence and helping intentions in supporting …

Relational Abstraction In Early Childhood: Three Cultures And Three Trajectories, Alexandra Carstensen, Minju Kim, Gayoung Kim, Meizi Jin, Minjin Kang, Youngon Choi, Caren M. Walker

Psychology Faculty Articles and Research

Abstract reasoning in early childhood is often described as following a "relational shift," over which children become increasingly sensitive to relations. However, recent work has challenged the generality of this account, showing that children in the US and China follow distinct trajectories in a relational match-to-sample task (Carstensen et al., 2019). This difference aligns with multiple cultural and linguistic factors implicated in relational reasoning, in which English speakers in the US and Mandarin speakers in China appear at opposite ends of a continuum spanning from a focus on objects (US) to relations (CN). We explore early relational reasoning in a …

Israeli Palestinian Conflict, Lucille Hall

All Capstone Projects

The Israeli-Palestinian conflict is a complex enduring challenge. This research will take an interdisciplinary approach integrating history, political science, and sociology, perspectives to analyze the conflict. By examining the interplay of historical narratives, political decisions, and cultural identities, the study aims to provide an understanding of the conflicts root cause and perpetuating dynamics. The research will explore the best innovative pathways to take to bring peace to the Middle East. The goal is to introduce a three-state solution.

Fda's Revolving Door: Reckoning And Reform, Laura Karas

Articles

Recent controversy over the FDA's approval of the Alzheimer's therapy Aduhelm (aducanumab) and the Duchenne muscular dystrophy therapy Exondys 51 (eteplirsen) called into question the impartiality and independence of high-level FDA regulators. Atypical associations between FDA regulators and pharmaceutical company sponsors, in addition to fierce internal disputes over the adequacy of the evidence, elicited criticism and triggered concern about potential undue influence at the FDA. The revolving door is one persistent source of undue influence that overshadows the discharge of FDA regulators' duties to the public. Exit from government to private-sector employment via the "revolving door" is a frequent occurrence …

Brokered Abuse, Thomas E. Kadri

Articles

No abstract provided.

`Representing And Being Represented In Turn’ – A Symposium On Hélène Landemore’S Open Democracy, Ethan J. Leib

Faculty Scholarship

No abstract provided.

Overlooked Sex And Gender Aspects Of Emerging Infectious Disease Outbreaks: Lessons Learned From Covid-19 To Move Towards Health Equity In Pandemic Response, Lynn Lieberman Lawry, Roberta Lugo-Robles, Vicki Mciver

Journal Articles: Epidemiology

Sex and gender issues are especially important in emerging infectious diseases (EIDs) but are routinely overlooked despite data and practice. Each of these have an effect either directly, via the effects on vulnerability to infectious diseases, exposures to infectious pathogens, and responses to illness, and indirectly through effects on disease prevention and control programs. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the viral agent of coronavirus disease 2019 (COVID-19) has underscored the importance of understanding the sex and gender impacts on pandemics. This review takes a broader looks at how sex and gender impact vulnerability, exposure risk, and treatment and …

Post-Traumatic Stress Disorders Among Syrian Refugees Residing In Non-Camp Settings In Jordan, Iman A. Basheti, Shahnaz Mohammed Ayasrah, Rajaa Ali Al-Qudah

Saudi Medical Journal

Objectives: To measure the prevalence and severity of post-traumatic stress disorders (PTSD) among Syrian refugees and explore its association with various factors. Methods: A cross-sectional study was carried out among a convenience snowball sample of Syrian refugees residing in non-camp settings in Jordan in 2019. A 4-part self-administered structured questionnaire was used to collect data. Part one included socio-demographic data, part 2 included an Arabic version of Harvard Trauma Questionnaire (HTQ) (part I: trauma event and part IV: trauma symptoms), part 3 was related to participants’ physical symptoms, and part 4 to participants’ satisfaction with the healthcare they received. Results: …

Physical Activity Preference And Participation In Middle School Age Students In Kentucky, Fabian Correia

Theses and Dissertations--Kinesiology and Health Promotion

Physical activity (PA) in youth is significant as it begins to lay the fountain for a healthier lifestyle as children age. The benefits of being regularly physically active are plentiful as it improves muscle strength, cardiovascular, fitness, and cognitive functions (Rodgers, 2008). However, oftentimes in physical education classes, the voice of the student tends to go unheard. The purpose of this study was to determine how the perception or preference to be physically active differs by age, gender, and/or ethnicity in a middle school setting. The goal of this study is to shed ligt on how building a more inclusive …

An Exploration Of Athlete Thoughts And Perceptions Of Cohesion In Coacting Sports, Jared Scott Hrabcak

Theses and Dissertations--Kinesiology and Health Promotion

Cohesion is a central element in group dynamics that contributes to a team’s functioning and performance. Most of the cohesion research to date has focused on the dynamic within interacting sport teams (i.e., football, basketball, soccer) but has looked past coacting teams (i.e., golf, tennis, cross-country running). While interacting sports command worldwide popularity, a significant portion of student athletes compete in coacting sports and represent the bulk of NCAA affiliated participants on the world stage at the Olympics. Thus, with such status on the world stage of competition, the investigation of coacting sports is justified. Therefore, the purpose of this …

The Effect Of Physical Activity Courses On The Motivation For Physical Activity In College Students: A Scoping Review, Erica Fauste Waizenhofer Hill

Theses and Dissertations--Kinesiology and Health Promotion

The lack of physical activity and exercise participation has been an ongoing
problem for young adults aged 18-24. Universities and colleges worldwide offer a variety of required and elective physical activity courses for college credit to increase active participation in lifelong healthy lifestyles. This scoping review collected studies on college students’ motivation to participate in physical activity. The courses were taught using methods based on motivational theories. The authors of the studies collected information from the students before and after the classes to gather data on the theoretical framework’s effect on the students, if any. This review compiles this information, …

Reliability And Validity Of A Commercial Running Power Meter To Indicate Metabolic Workload During Endurance Running, James Harris Hudgins Iii

Theses and Dissertations--Kinesiology and Health Promotion

Commercial running power (RP) meters may provide endurance runners and coaches with improved precision for monitoring running intensity. Cyclists rely upon the relationship between cycling power and metabolic demand to regulate physiological intensity during training and racing, independent of changes in the physical environment (e.g., terrain, wind). Research demonstrates strong reliability and validity for a specific RP meter to indicate metabolic demand within controlled running conditions. However, several potential influences on this relationship have not been investigated. Therefore, four studies were conducted with the following aims:

- Study 1: Determine the inter-limb reliability and validity of a single-limb-based RP meter …

Food Insecurity On College Campuses: Addressing The Issue Through A Student-Centered Perspective, Thomas Ard

Theses and Dissertations--Kinesiology and Health Promotion

Research indicates food insecurity (FI) has become a consistent challenge for college students. However, more is needed regarding the students' lived experiences of food insecurity following the COVID-19 pandemic. Universities play a vital role in assisting students with food insecurity through food assistance programs, on-campus resources, and financial help, which impacts their physiological needs and academic performance. A better understanding of what influences students' perceptions and decisions about whether to engage in these resources is essential.

This dissertation's purpose was to explore how college students living with food insecurity experience engaging in food assistance programs (FAP). The study used a …

The Relationship Of Multidimensional Athlete Characteristics Versus Competition Performance And Participation In American Football Players, Alex Brownell

Theses and Dissertations--Kinesiology and Health Promotion

BACKGROUND: Athlete evaluation in American football is dominated by the evaluation characteristics that underly key performance indicators (KPI’s) in the physical domain of performance. Team sport athlete performance is comprised of a combination of attributes in the physical, technical, tactical, and mental domains of performance. Using only KPI’s in the physical domain of performance to predict competition performance of American football athletes is challenging due to the differences in performance outcomes of the varying positions in American football and absence of the other performance dimensions that are not accounted for. Advances in athlete assessment have revolutionized the process of evaluating …

Kentucky Teacher Social-Emotional Competence, Burnout, And School Climate, Monica Mundy

Theses and Dissertations--Kinesiology and Health Promotion

Teachers are tasked with supporting student learning and academic achievement. Teachers must establish social-emotional competence within themselves to support students' social-emotional learning. Increased teachers' social-emotional competence could lead to favorable student social, emotional, and academic outcomes. To effectively do so, school officials, parents, and community members should support teachers' social-emotional competence equally.

This study examined the relationship between Kentucky teachers' social-emotional competence, burnout, and school climate. The prosocial classroom model provided the theoretical framework for this study, including the five dimensions of social-emotional competence (self-awareness, self-management, social awareness, relationship skills, and responsible decision-making), teacher burnout, and school climate. The hypothesis …

Risk At The Boundaries Of Social Work: An Editorial, Rory Crath, Jeremy Dixon, Jo Warner

School for Social Work: Faculty Publications

In this editorial we introduce a special thematic collection of articles which focus on how risk operates, or is conceptualised, at the boundaries of social work practice. The collection includes theoretical, empirical, and practice-oriented articles, each of which critically engages with contemporary debates about risk and social work and its complex intersections with boundary making in diverse fields. These fields include social work with older people, child sexual abuse and exploitation, and people with learning disabilities. We begin the editorial with a brief account of how social work can be defined and the competing ideological traditions that underpin differing forms …

Migraine Among Neurology Outpatient Attendants In Mansoura University: Sociodemographic And Migraine Comorbidities Analysis, Mohammad Youssif Ismail Ibrahim, Tamer Mohammad Belal, Hossam Mohammad Egila, Ahmed Gamal Azab

Mansoura Medical Journal

Background: Twelve percent of the population is thought to suffer from migraines. 1% to 2% of individuals worldwide suffer from chronic migraine (CM). Approximately 2.5% of cases who have episodic migraine (EM) develop CM. A number of risk factors are linked to the development of CM. Independent of medication; there is a sizable short-term variance in migraine frequency. Sleep difficulties, psychological illness, and cardiovascular disease are all linked to migraine. It is the second most incapacitating illness globally. Objectives: To evalaute the sociodemographic characteristics of migraineurs and their different co-morbidities. Patients and methods: A cross-sectional study with analytic component was …

The Effect Of Adding Magnesium Sulphate Versus Dexmedetomidine As An Adjuvant To Bupivacaine In Ultrasound Rectus Sheath Block On Postoperative Analgesia In Patients Undergoing Abdominal Aortic Surgery, Ghada Fouad Amer, Mohamed Younes Yousef Abd Allah

Mansoura Medical Journal

Background: With significant advancements in the area, post-operative pain management after abdominal procedures has garnered attention lately. Despite these developments, post-operative pain is still difficult to manage and is sometimes not sufficiently addressed, which causes worry, tension, and discontent in the patient. In addition to having negative medical impacts, inadequate pain management may also have negative psychological, economic, and societal repercussions. Aim and objectives: To assess the analgesic impacts of dexmedetomidine against magnesium sulphate when used as a bupivacaine adjuvant during ultrasound-guided bilateral rectus sheath block during abdominal aortic surgery. Patients and methods: Over the course of five months, 40 …

Conversational Agents For Mental Health And Well-Being: Discovering Design Recommendations Using Text Mining, Abdullah Wahbeh, Mohammad Al-Ramahi, Omar El-Gayar, Ahmed Elnoshokaty, Tareq Nasralah

Research & Publications

Conversational agents are increasingly being used by the general population due to shortages in healthcare providers and specialists, and limited access to treatments. They are also used by people to deal with loneliness and lack of companionship. As these apps are increasingly replacing real humans, there is a need to explore their design features and limitations for better design of conversational apps. Using text mining and topic modeling, this study analyzed a total of 126,610 reviews about Replika, a popular and well-established conversational agent mobile app. Our results emphasized current practices for designing conversational apps while at the same time …

Is Artificial Intelligence Attractive? An Empirical Study On User’S Intention To Use Ai-Enabled Applications, Omar F. El-Gayar, Gary Yu Zhao, Cindy Zhiling Tu

Research & Publications

Artificial Intelligence (AI) technologies such as machine learning (ML), natural language processing (NLP), and image recognition, are being incorporated into a wide variety of applications. These AI-enabled applications (AI apps) promise to reshape people's lives. However, despite the proliferation of AI-related research, very little research has focused on how AI apps' unique characteristics affect an individual's adoption behavior. This study examines factors influencing an individual's intention to use AI apps with a proposed research model based on the Task Technology Fit (TTF) as the underlying theoretical framework. The research model is empirically evaluated using the survey data and SEM method. …

The Well-Being Of A University: The Relationship Between Gratitude And Organizational Commitment On Faculty Members' Intention To Stay, Brenda Merkel, Kristi Bockorny, Amber Henderson, Aaron Scholl

Research & Publications

Retaining good employees can be difficult , and no organization is immune. This study investigated the relationship between gratitude and organizational commitment to determine if they can predict the intention to stay among university faculty. Specifically, this study analyzed gratitude, a construct that has not been researched much in the workplace. There was a significant relationship between gratitude on organizational commitment. Gratitude and organizational commitment were important predictors of intention to stay. Gratitude was supported as a moderator between organizational commitment and intention to stay. Organizations should incorporate posititve reinforcements to express gratitude to increase organizational commitment and intent to …

Annual Report 2022-2023, Office Of Community Engagement

News, Magazines and Reports

Letter from Annie Johnson, Director, and Arlete Perez Paez, Assistant Director:

As we celebrate the beginning of summer, we pause to reflect on the changes, successes, and collaborations of this past academic year.

In January, we welcomed Francis Origanti as the interim Vice President for the Mission Integration department and are assisting with the search of Executive Director for the department as well. Additionally, Arlete Perez Paez was promoted to Assistant Director; the office also will be hiring a fulltime Coordinator for Community Partnerships in time for start of the new academic year.

We are also excited to share that …

Moderating Effects Of Relationship Length And Contact Frequency On Customer Citizenship Behaviors, Laee Choi, Mi Ran Kim

ICHRIE Research Reports

Studies show that contact frequency and relationship length impact co-creative and in-role behaviors with service providers. However, their influence on extra-role or customer citizenship behaviors (CCBs) remains unexplored. This study delves into the moderating role of relationship length and contact frequency within the CCB model. Utilizing an online survey (n = 665), the study unveils that perceived justice’s impact on affective commitment is not moderated by contact frequency, whereas the impact is stronger in short-term than in longer-term relationships. The perceived support-affective commitment-CCBs relationship is stronger in high contact than in low contact group. Similarly, the relationship is stronger for …

Thei Student Applied Research Presentations Sarp 2023, Research Office Thei

THEi Student Applied Research Presentations (SARP)

No abstract provided.

2023 Create, Grow, Scale Entrepreneurship Convening: Summary Report, Research Institute For Social Equity At Virginia Commonwealth University

Research Institute for Social Equity

In partnership with Capital One Insights Center, the Research Institute for Social Equity (the Institute) hosted a convening to discuss the ecosystem around Black and Hispanic businesses in Richmond, Virginia. This full-day experience brought together thought leaders, policymakers, practitioners, community influencers, and entrepreneurs from the greater Richmond community to strategize how to translate research into action toward economic outcomes that benefit Black and Hispanic entrepreneurs. This summary paper offers an overview of the sessions and outcomes of this convening.

A Qualitative Study On The Financial Education Of Young Black Men, Sue M. May

University of the Pacific Theses and Dissertations

Financial literacy awareness is low among young adults, and financial literacy among Black college students is significantly lower than in other groups (Singh, 2018). However, there is little to no research on why financial literacy is so low among young Black men between 18 and 25. Few studies specifically show how financial literacy and decision-making may be related to their family economics and socialization for young Black men. Using Critical Race Theory and Family Financial Socialization theoretical frameworks, this dissertation project examined a sample of seven young self-identified Black men ages 24 to 25 years old in Northern California Bay …