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Articles 1261 - 1290 of 73541
Full-Text Articles in Entire DC Network
Ints6 And The Integrator Phosphatase Module Tune The Efficiency Of Select Premature Transcription Termination Events, Rina Fujiwara, Si-Nan Zhai, Dongming Liang, Aayushi P Shah, Matthew Tracey, Xu-Kai Ma, Christopher J Fields, María Saraí Mendoza-Figueroa, Michele C Meline, Deirdre C Tatomer, Li Yang, Jeremy E Wilusz
Ints6 And The Integrator Phosphatase Module Tune The Efficiency Of Select Premature Transcription Termination Events, Rina Fujiwara, Si-Nan Zhai, Dongming Liang, Aayushi P Shah, Matthew Tracey, Xu-Kai Ma, Christopher J Fields, María Saraí Mendoza-Figueroa, Michele C Meline, Deirdre C Tatomer, Li Yang, Jeremy E Wilusz
Children’s Nutrition Research Center Staff Publications
The metazoan-specific Integrator complex catalyzes 3' end processing of small nuclear RNAs (snRNAs) and premature termination that attenuates the transcription of many protein-coding genes. Integrator has RNA endonuclease and protein phosphatase activities, but it remains unclear if both are required for complex function. Here, we show IntS6 (Integrator subunit 6) over-expression blocks Integrator function at a subset of Drosophila protein-coding genes, although having no effect on snRNAs or attenuation of other loci. Over-expressed IntS6 titrates protein phosphatase 2A (PP2A) subunits, thereby only affecting gene loci where phosphatase activity is necessary for Integrator function. IntS6 functions analogous to a PP2A regulatory …
Metagenomic Analysis Unveils The Microbial Landscape Of Pancreatic Tumors, Sheema Khan, Goutam Banerjee, Saini Setua, Daleniece Jones, Bhavin Chauhan, Anupam Dhasmana, Pratik Banerjee, Murali M. Yallapu, Stephen Behrman, Subhash C. Chuahan
Metagenomic Analysis Unveils The Microbial Landscape Of Pancreatic Tumors, Sheema Khan, Goutam Banerjee, Saini Setua, Daleniece Jones, Bhavin Chauhan, Anupam Dhasmana, Pratik Banerjee, Murali M. Yallapu, Stephen Behrman, Subhash C. Chuahan
School of Medicine Publications
The composition of resident microbes in the human body is linked to various diseases and their treatment outcomes. Although studies have identified pancreatic ductal adenocarcinoma (PDAC)-associated bacterial communities in the oral and gut samples, herein, we hypothesize that the prevalence of microbiota in pancreatic tumor tissues is different as compared with their matched adjacent, histologically normal appearing tissues, and these microbial molecular signatures can be highly useful for PDAC diagnosis/prognosis. In this study, we performed comparative profiling of bacterial populations in pancreatic tumors and their respective adjacent normal tissues using 16S rRNA-based metagenomics analysis. This study revealed a higher abundance …
Must Courts Recalibrate Tort Law Governing Firearms In Light Of The Second Amendment?, Lars Noah
Must Courts Recalibrate Tort Law Governing Firearms In Light Of The Second Amendment?, Lars Noah
University of Cincinnati Law Review
The rules governing the scope of liability in cases where firearms cause injuries—some well-established, others fairly novel—help to define the responsibilities of users, owners, and sellers of these popular but dangerous products. As the U.S. Supreme Court has recently expanded an individual’s right to keep and bear arms, some have wondered whether the Second Amendment might operate to limit the reach of these various tort doctrines. Sixty years ago, the Court started to constitutionalize various aspects of state common law, most famously using the First Amendment to limit defamation claims but in other respects as well. A comparable approach to …
Section 230 As Civil Rights Statute, Enrique Armijo
Section 230 As Civil Rights Statute, Enrique Armijo
University of Cincinnati Law Review
Many of our most pressing discussions about justice, progress, and civil rights have moved online. Activists advocating for social change no longer need to be in the same physical space to connect with others who share their challenges and aspirations. But the convergence of mobility, connectivity, and technology is not the only reason why. Thanks to Section 230 of the Communications Decency Act’s (“Section 230”) immunity for online platforms, websites, and their hosts, speakers can engage in speech about protest, equality, and dissent without fear of collateral censorship from governments, authorities, and others in power who hope to silence them. …
Perceived Importance Of Ultrasound Vascular Access Education Among Residents, Raquel Lamarche, Jared Marx, Jihyun Ma, Stephanie Claudy
Perceived Importance Of Ultrasound Vascular Access Education Among Residents, Raquel Lamarche, Jared Marx, Jihyun Ma, Stephanie Claudy
Graduate Medical Education Research Journal
Background: Peripheral intravenous catheter (PIVC) failure and difficult intravenous access (DIVA) are pervasive issues causing patient suffering and increased costs. Despite their prevalence, there is a gap in internal medicine and pediatric resident training to manage these challenges effectively.
Objective: This study aimed to assess the value of ultrasound-guided-PIVC (USGPIVC) education for internal medicine and pediatric residents and the impact of a 1-hour multidisciplinary workshop on their knowledge and confidence.
Methods: A cross-sectional survey study was conducted at an academic medical center in 2022 to assess residents’ perceptions of USG-PIVC education. This was followed by a USG-PIVC simulation-based workshop with …
Engaging Community Partners To Enrich Preschoolers Learning Experiences With Dramatic Inquiry, Kathleen M. Farrand, Wendy Peia Oakes, Megan Troxel Deeg, Katelyn Jaworksi, Veronica Leon
Engaging Community Partners To Enrich Preschoolers Learning Experiences With Dramatic Inquiry, Kathleen M. Farrand, Wendy Peia Oakes, Megan Troxel Deeg, Katelyn Jaworksi, Veronica Leon
Journal of the Arts and Special Education
Interdisciplinary teams of adults are needed to enhance the capacity of schools to provide the most appropriate educational experiences for young children who have or are at risk for developmental delays and disabilities (Division for Early Childhood, 2014). When educators, families, and community partners connect around shared goals, we begin to reimagine instructional opportunities and create more equitable access to educational resources for children and families. We share insights from community partners who participated in a collaborative dramatic inquiry study designed to enrich preschoolers’ learning experiences and serve children and families.
Culturally Sustaining Math Word Problem Instruction With Hip-Hop Story Schemas, Michelle J. Cook, Jonte C. Taylor, Elizabeth M. Hughes, Thomas D. Deau
Culturally Sustaining Math Word Problem Instruction With Hip-Hop Story Schemas, Michelle J. Cook, Jonte C. Taylor, Elizabeth M. Hughes, Thomas D. Deau
Journal of the Arts and Special Education
On August 11, 2023, Hip-Hop celebrated its 50th anniversary. In honor of this milestone, we share an activity that is designed to harness the power and art of Hip-Hop to support learning in mathematics for students with and without exceptionalities. Using a vignette, we examine why culturally sustaining practices are pivotal to learning and how teachers can collaborate with middle-school students to strengthen an evidence-based practice such as schema-based instruction by honoring the funds of knowledge that students possess. The activity includes (a) the creation of culturally relevant word problems in mathematics, (b) schema-based instruction for solving additive-type word …
Multisensory Adaptations: Creating Art With Students Who Are Blind And Low Vision, Jasmine Begeske, Leslie Walsh, David Ray Miranda
Multisensory Adaptations: Creating Art With Students Who Are Blind And Low Vision, Jasmine Begeske, Leslie Walsh, David Ray Miranda
Journal of the Arts and Special Education
The main purpose of this article is to present approaches and strategies to making 2-D visual arts instruction meaningful and accessible for students who are blind or low vision. The suggestions provided within this article are based on current literature, researcher observations, and the contributions of an experienced, practicing art teacher at the Indiana School for the Blind and Visually Impaired.
Book Review: Inequality In America: Causes And Consequences, Eya Mahouachi
Book Review: Inequality In America: Causes And Consequences, Eya Mahouachi
The Journal of Values-Based Leadership
Inequality in America: Causes and Consequences is a recent book authored by Rycroft (economics, Univ. of Mary Washington, Fredericksburg, VA) and Kinsley (business law, Univ. of Mary Washington, Fredericksburg, VA) and was written by scholars, advanced graduate students, and expert practitioners. Their book attempts to bridge the gap in scholarship and practice by incorporating the causes and consequences of history, the current state of inequality in the United States, and future consequences if left unresolved. This book is structured according to fundamental topics such as education, healthcare, housing, environmental issues, and the justice system. Using an effective approach to teaching …
Miracle On The High Seas, A True Story: A Case Of Faith, Heroism, Love, And Compassion, Emilio Iodice
Miracle On The High Seas, A True Story: A Case Of Faith, Heroism, Love, And Compassion, Emilio Iodice
The Journal of Values-Based Leadership
No abstract provided.
"Being On God’S Side": Biblical Leaders On Wokeness, Social Justice, Cancel Culture, White Privilege, And Other Controversial Terms, Hershey H. Friedman, Svetlana Vlady
"Being On God’S Side": Biblical Leaders On Wokeness, Social Justice, Cancel Culture, White Privilege, And Other Controversial Terms, Hershey H. Friedman, Svetlana Vlady
The Journal of Values-Based Leadership
Terms such as “woke,” “social justice,” “cancel culture,” “identity politics,” “politically correct,” “critical race theory,” and “DEI” have been increasingly misused and politicized by both the left and the right in recent years. This paper will examine the Hebrew Bible and explore what it says about social justice, compassion for the indigent, inclusion, and many other terms causing such an uproar. The authors assert that the ancient prophets, the true social justice warriors, would be horrified by the actions of both the left and right.
The Trader Joe’S Way (To Success), Ritch Eich, Joan Taylor Cummings Eich
The Trader Joe’S Way (To Success), Ritch Eich, Joan Taylor Cummings Eich
The Journal of Values-Based Leadership
No abstract provided.
The Intersection Of Leader-Follower Trade (Lft) And Leader-Member Exchange (Lmx) In Alleviating Work-Family Conflict (Wfc), Ashlie James
The Intersection Of Leader-Follower Trade (Lft) And Leader-Member Exchange (Lmx) In Alleviating Work-Family Conflict (Wfc), Ashlie James
The Journal of Values-Based Leadership
In an organizational context, employees are more than mere followers but individuals with multiple roles beyond their employment which interact and influence the way they work. When the demands from work and family life collide, scholars describe this inter-role conflict as work–family conflict (WFC) where the role pressures from work and family are mutually incompatible creating increased feelings of strain and decreased life and job satisfaction which affect their work performance and commitment (Blanch & Aluja, 2012; Hagqvist et al., 2017). Given the importance of having work-life balance, human resource management (HRM) theory argues work flexibility, such as the opportunity …
Ethical Leadership: A Study Of Behaviors Of Leaders In Higher Education Today, Jonathan Hubchen, Samuel L. Wyatt, Michael Burnett
Ethical Leadership: A Study Of Behaviors Of Leaders In Higher Education Today, Jonathan Hubchen, Samuel L. Wyatt, Michael Burnett
The Journal of Values-Based Leadership
The primary purpose of this study was to determine the behaviors of an ethical leader as perceived by tenured and tenure-track faculty at a research university (RU/VH) in the southeastern portion of the United States. The researcher utilized a researcher-designed survey instrument which consisted of twenty possible behaviors of an ethical leader and selected demographic characteristics.
Examination of the study results revealed that the majority of respondents were male (66.20%) and tenured (75.00%). Additionally, the largest group were Professors (49.60%), and had been at the study institution for less than l0 years (38.20%). The characteristics that were most related to …
Three Conditions For Vertical Leadership Development: Impact Of Personal Experiences, Kevin Coopersmith
Three Conditions For Vertical Leadership Development: Impact Of Personal Experiences, Kevin Coopersmith
The Journal of Values-Based Leadership
Vertical leadership development, an emerging body of leadership research based around expanding an individual’s capacity to think, make decisions, and understand themselves and the world around them, stands as a unique solution to address the leadership skills gap at a time of global complexity and change. Petrie’s (2015) model of the three conditions for vertical leadership development to take place was analyzed through the lived experiences of eight leaders who had successfully completed personal development plans and shared their experiences through a narrative-based qualitative study. Of the eight participants, three participants filled all three conditions and demonstrated a higher level …
Belief And Hope: Propositional Antecedents Of A Moral Life, Joseph P. Hester
Belief And Hope: Propositional Antecedents Of A Moral Life, Joseph P. Hester
The Journal of Values-Based Leadership
No abstract provided.
A Journey To Managing Stress: My Story, James J. Lynch
A Journey To Managing Stress: My Story, James J. Lynch
The Journal of Values-Based Leadership
No abstract provided.
The Art Of Transformational Leadership: A Key To A High-Performance Company, Mostafa Sayyadi, Michael J. Provitera
The Art Of Transformational Leadership: A Key To A High-Performance Company, Mostafa Sayyadi, Michael J. Provitera
The Journal of Values-Based Leadership
The purpose of this research is to explore how transformational leadership impacts organizational performance. We posit that transformational leadership is a significant indicator of organizational performance. This article suggests that executives who act as transformational leaders affect organizational outcomes. In particular, this article raises a vital question as to how managers can successfully contribute to performance at the organizational level. It highlights the potential consequences of applying transformational leadership.
Upstalsboom - An Example Of Caring Economics, Silvia Hedenigg, Bodo Janssen
Upstalsboom - An Example Of Caring Economics, Silvia Hedenigg, Bodo Janssen
The Journal of Values-Based Leadership
In recent years, innovative approaches to corporate culture and leadership, such as the concept of "New Work" and its meaning and value-oriented corporate management, are gaining attention in science and organizational practice. However, critical voices doubt their feasibility citing challenges associated with their benefit realization. Nevertheless, through a case study of Upstalsboom, a German medium-sized family business in the tourism industry, the authors of this article illustrate how a people-centered, meaning-oriented corporate culture, and values-based leadership are not only possible and successful, but also sustainable from a crisis-resistant stability and resilience perspective. A reconstruction of the company's development along biographical …
People, Processes, Systems, And Leadership — Keys To Organizational Performance, Cam Caldwell, Khalfan R. Al Asmi, Zulaikah Albusaidi, Rayan Esmaail
People, Processes, Systems, And Leadership — Keys To Organizational Performance, Cam Caldwell, Khalfan R. Al Asmi, Zulaikah Albusaidi, Rayan Esmaail
The Journal of Values-Based Leadership
Current evidence about successful organizations emphasizes the importance of integrated organizational factors that combine to convey a consistent message to employees that is the essence of an effective organizational culture (Beer, 2009; Shein & Schein, 2016). Although there is much that is positive about the achievements that some organizations are making to create a sustainable organizational culture, there is also overwhelming evidence that organizations and their leaders are struggling to earn the commitment and followership of their employees (Clifton & Harter, 2019; Edelman, 2023).
How Values And Value Clarity Still Matter: An Extended Study Of Global Managers, Barry Posner, Joongoo Han
How Values And Value Clarity Still Matter: An Extended Study Of Global Managers, Barry Posner, Joongoo Han
The Journal of Values-Based Leadership
The importance of values has been continuously studied, and the consensus is that values matter. However, the issue of just how much they matter remains open to various interpretations, including the importance of value clarity and congruency. This study examined the impact of personal and organizational values clarity on commitment, performance, and motivation. An online survey involving 8,442 managers was collected in the same way as previous studies on value clarity and consistency (Posner & Schmidt, 1993; Posner, 2010), but unlike previous studies, managers outside the United States were included. Both personal values congruency and organizational values clarity significantly impacted …
Humanity As Community: A Prescription For The Ethically Possible, Joseph P. Hester
Humanity As Community: A Prescription For The Ethically Possible, Joseph P. Hester
The Journal of Values-Based Leadership
No abstract provided.
"Treat Them Like Volunteers" ─ The Key To Employee Engagement, Cam Caldwell
"Treat Them Like Volunteers" ─ The Key To Employee Engagement, Cam Caldwell
The Journal of Values-Based Leadership
No abstract provided.
When Leadership Meets A Vision Of Love And Justice: The Art Of Leading For Social Justice, Aaliyah Baker
When Leadership Meets A Vision Of Love And Justice: The Art Of Leading For Social Justice, Aaliyah Baker
The Journal of Values-Based Leadership
No abstract provided.
Robust Gasification Trial Results For A Variety Of Difficult-To-Recycle Packaging-Related Materials, Bruce A. Welt
Robust Gasification Trial Results For A Variety Of Difficult-To-Recycle Packaging-Related Materials, Bruce A. Welt
Journal of Applied Packaging Research
Currently, recycling requires nearly absolute sorting of materials to accommodate the limited capabilities of existing recycling infrastructure. Whether a material is “recyclable” depends more on the method of recycling than the material itself. Our dependence upon sorting has limited success of recycling and has stifled our ability to achieve circular economy sustainability with plastic packaging materials. Our dependence upon sorting is rooted in our material-specific recycling processes. However, newer robust recycling processes are commercially available that reduce or eliminate the need to sort waste, and can convert mixed waste into primary feedstock chemicals, such as methanol for subsequent manufacture of …
Book Review Reading Images: The Grammar Of Visual Design, Wim Honders
Book Review Reading Images: The Grammar Of Visual Design, Wim Honders
Journal of Media Literacy Education
No abstract provided.
Critically Analyzing The Meanings Of “Critical” Media Literacy, W. James Potter
Critically Analyzing The Meanings Of “Critical” Media Literacy, W. James Potter
Journal of Media Literacy Education
This study provides a critical analysis into how authors of publications about critical media literacy express what they mean by the term. The use of multiple strategies to examine the degree to which these authors exhibit a sharing of meaning led to the conclusion that there are far more differences than commonalities across definitions of critical media literacy. The implications of this conclusion raise important questions about the value of a literature where authors seem to express so many different meanings for the concept that they use to label their common concern.
Mapping Media And Information Literacy Skills During And After Covid-19, With Special Reference To Online Education, And Commerce And Trade, Omwoyo Bosire Onyancha
Mapping Media And Information Literacy Skills During And After Covid-19, With Special Reference To Online Education, And Commerce And Trade, Omwoyo Bosire Onyancha
Journal of Media Literacy Education
This paper examines literature from the COVID-19 period (2020-2022) to outline prevalent themes and essential competencies in the post-COVID era. Employing informetrics within a quantitative research approach, the study scrutinizes Scopus database data using COVID-19, e-learning, e-commerce, and media and information literacy terms. Results reveal a surge in scholarly focus on e-commerce, online learning, e-health, and ICTs, including social media. Identified were 355 media and information literacy terms, with digital, information, health, and media literacy at the forefront. Moreover, 244 corresponding competencies and skills were noted. The study emphasizes the necessity for comprehensive media and information literacy programs, diverse competencies, …