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2023

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Choosing A Sophisticated, Robust, And Secure Programming Language, J. Simon Richard Dec 2023

Choosing A Sophisticated, Robust, And Secure Programming Language, J. Simon Richard

The Downtown Review: An Interdisciplinary Journal Written and Peer-Reviewed by Mandel Honors College Students at Cleveland State University

This paper explores which programming languages maximize the quality and efficiency of software development projects requiring high levels of sophistication, security, and stability. Of the four languages discussed in this paper—C, C++, Java, and Rust—we conclude that Rust is the best for this application.


An Investigation Into Dietary Fibre Intake, Bowel Function And Mood Among A Sample Of Irish Adults, Sophie Mulligan, Ellen Lynch, Suzanne Doyle Dec 2023

An Investigation Into Dietary Fibre Intake, Bowel Function And Mood Among A Sample Of Irish Adults, Sophie Mulligan, Ellen Lynch, Suzanne Doyle

SURE Journal: Science Undergraduate Research Experience Journal

Background

Previous studies have examined the relationship between dietary fibre intake and mood and bowel function separately, however, no cross-sectional study has yet explored the relationship between all three variables. This study examines the association between dietary fibre intake, bowel function and mood in a cohort of Irish adults at a university campus.

Methods

A cross-sectional study was conducted. An online questionnaire was distributed to staff and students of TU Dublin through email and publicised using posters. Three validated surveys were used in the design of the questionnaire, to assess dietary fibre intake, mood and bowel function. All staff and …


The Potential Of Stem Cell Therapy In Multiple Sclerosis Treatment: A Review, Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham Dec 2023

The Potential Of Stem Cell Therapy In Multiple Sclerosis Treatment: A Review, Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham

SURE Journal: Science Undergraduate Research Experience Journal

Multiple Sclerosis is an autoimmune and neurodegenerative disease of the central nervous system. There are currently 2.8 million people living with Multiple Sclerosis worldwide, including 9000 people in Ireland, with a prevalence of 193 per 100,000 people. Symptoms of Multiple Sclerosis include sensory loss, fatigue, cognitive dysfunction, spasticity, depression, optic neuritis, gait ataxia, diplopia, and loss of bladder control. Currently, there is no standardised treatment or cure for Multiple Sclerosis with many strategies focusing on symptoms. Stem cells have emerged as promising approaches for Multiple Sclerosis therapeutics. Clinical trials primarily focus on mesenchymal stem cell-based therapies for Multiple Sclerosis. Furthermore, …


“I’M One Of Those Crazy Feminists!”: Young Women’S Embodiment Of The Feminist Killjoy During The Transition From Secondary School To Higher Education, Abigail Wells Dec 2023

“I’M One Of Those Crazy Feminists!”: Young Women’S Embodiment Of The Feminist Killjoy During The Transition From Secondary School To Higher Education, Abigail Wells

Journal of International Women's Studies

No abstract provided.


A Review Of “Making Black Girls Count In Math Education: Black Feminist Vision For Transformative Teaching, Michelle Craddock Guinn Dec 2023

A Review Of “Making Black Girls Count In Math Education: Black Feminist Vision For Transformative Teaching, Michelle Craddock Guinn

Feminist Pedagogy

No abstract provided.


Collaborations, Not Competitions, Can Reduce Gender Disparities In Robotics, Sonia Roberts, Alysson Light Dec 2023

Collaborations, Not Competitions, Can Reduce Gender Disparities In Robotics, Sonia Roberts, Alysson Light

Feminist Pedagogy

No abstract provided.


Feminist Biology: Towards Gender Equity In The Biology Curriculum, Nicole Danos, Carla Y. Bonilla, Sofia Leung Dec 2023

Feminist Biology: Towards Gender Equity In The Biology Curriculum, Nicole Danos, Carla Y. Bonilla, Sofia Leung

Feminist Pedagogy

The current curriculum in STEM is a product of historically unequal representation of genders in the science community. As a result, most attention has been given to male biology, creating a knowledge gap that has affected our social and political perspectives, such as an underinvestment in women’s health research. Feminist biology seeks to provide equal time and weight to the impact of sex as a biological factor, using inclusive definitions of biological sex that go beyond the male/female binary. Feminist pedagogy is a method of teaching that involves engaged learning and reflection in order to create a community of learners …


Centering Equity In Stem Teaching: Stem Ideas That Change The World, Ileana Vasu Dec 2023

Centering Equity In Stem Teaching: Stem Ideas That Change The World, Ileana Vasu

Feminist Pedagogy

No discussion on equity/inequity makes sense without bringing power into that discussion. As instructors we need to ask questions such as “who decides and controls what knowledge is”, “whose identities are empowered and whose are erased”, “who has access and opportunity and who doesn’t”. Traditional teaching in STEM, including mathematics, assumes knowledge is objective, transmittable, repeatable to everyone. When educators follow a traditional curriculum, just like their teachers before them, they do so thinking their methods ensure equality and objectivity. These practices not only deny the role that Western patriarchal cultures have played in creating these so-called equitable practices, but …


Feminist Pedagogy In Stem: The Intersection Of Stem Pedagogy And Feminist Theory, Lesley-Ann Giddings, Candice R. Price Dec 2023

Feminist Pedagogy In Stem: The Intersection Of Stem Pedagogy And Feminist Theory, Lesley-Ann Giddings, Candice R. Price

Feminist Pedagogy

No abstract provided.


Differentiating Modernity (The System Of White Supremacy) And Generating Otherwise Worlds As Publicly Engaged Scholars: What’S Ontological Inquiry Got To Do With It?, Carolyne J. White, Arturo E. Osorio, Tim K. Eatman, Margaret J. Weiss Dec 2023

Differentiating Modernity (The System Of White Supremacy) And Generating Otherwise Worlds As Publicly Engaged Scholars: What’S Ontological Inquiry Got To Do With It?, Carolyne J. White, Arturo E. Osorio, Tim K. Eatman, Margaret J. Weiss

Turning Toward Being: The Journal of Ontological Inquiry in Education

Seeking an answer to Tina Turner’s refrain, “What’s Love Got to Do with It?” this article is a rebellious, messy, place-based and deeply collaborative conversation. We draw upon the legacy of theatre and social critique and adopt the literary present tense to evoke a brave intimate space for imagining possibilities beyond the academic conventions of the present epistemological order. We seek to illuminate how ontological inquiry may provoke powerful access to generating new worldmaking for climate justice, particularly when one is being a publicly engaged scholar. Why new worldmaking? Within this unprecedented time of racial reckoning, war, climate catastrophe and …


Efficacy Of Modified Psychotherapy To Mitigate Depression Among African American Adults And Older Adults: A Systematic Review, Bridget Ashaolu, Nassrine Noureddine Dec 2023

Efficacy Of Modified Psychotherapy To Mitigate Depression Among African American Adults And Older Adults: A Systematic Review, Bridget Ashaolu, Nassrine Noureddine

Pacific Journal of Health

It has been established that due to several factors, African American adults and older adults in the United States respond poorly to pharmacologic intervention in treating depression. The study will help to provide evidence and raise awareness on how to better serve the African American population with depression. This systematic review of the literature examines the effectiveness of using modified evidence-based psychotherapy and faith-based resources in improving depression among older African American adults over the use of conventional pharmacological intervention. 21 studies that recommended utilizing psychotherapy intervention to improve depression in this population were reviewed to better understand the need …


The Effects Of Volcanic Deposits On Human Preservation, Charles M. Nuncio Dec 2023

The Effects Of Volcanic Deposits On Human Preservation, Charles M. Nuncio

Culture, Society, and Praxis

No abstract provided.


Teaching And Teachings Of Black Mixed Girls As Unveiling Femme-Centered Anti-Blackness In Us Education, Miranda Mosley Dec 2023

Teaching And Teachings Of Black Mixed Girls As Unveiling Femme-Centered Anti-Blackness In Us Education, Miranda Mosley

Culture, Society, and Praxis

Through a lack of Black-centered, Black-empowering policies and strategies (Dumas, 2016), Black people are overlooked in the US public education system. Though this general disregard (and disdain) for Blackness in the education system is found to keep communities segregated and result in higher rates of expulsion and punishment for Black students (Dumas, 2014; Wun, 2016), we know relatively little about how experiences shape identities for Black girls in their schools. For Black girls, and specifically Black mixed race girls, we do know that physical attributes like hair texture and skin color shift the girls’ sense of racial identity (Hunter, 2016) …


Taking Responsibility, Robert M. Ackerman Dec 2023

Taking Responsibility, Robert M. Ackerman

Tennessee Journal of Law and Policy

No abstract provided.


St. George Tucker's Second Amendment: Deconstructing The True Palladium Of Liberty, Stephen P. Halbrook Dec 2023

St. George Tucker's Second Amendment: Deconstructing The True Palladium Of Liberty, Stephen P. Halbrook

Tennessee Journal of Law and Policy

No abstract provided.


Non-Fungible Tokens (Nfts) - Survey Of Current Applications, Evolution And Future Directions, Qaiser Razi, Aryan Devrani, Harshal Abhyankar, Gss Chalapathi, Vikas Hassija, Mohsen Guizani Dec 2023

Non-Fungible Tokens (Nfts) - Survey Of Current Applications, Evolution And Future Directions, Qaiser Razi, Aryan Devrani, Harshal Abhyankar, Gss Chalapathi, Vikas Hassija, Mohsen Guizani

Machine Learning Faculty Publications

Non-fungible tokens (NFTs) have become an exciting technology that provides a fresh perspective on asset ownership, provenance, and value exchange. NFTs, a blockchain-based technology, are distinct and indivisible cryptographic tokens used to confirm and record the ownership of digital and physical assets in an immutable and transparent way. The fundamental block of NFT is a smart contract built on a blockchain network. This contract contains specific information about the asset it represents, such as its unique identifier, metadata, and ownership details. The information is kept private and tamper-proof due to the decentralized and distributed structure of the blockchain, boosting faith …


Introductory Note: Ownership And Dominion In The Lands Of The Maya, Maya America Editors Dec 2023

Introductory Note: Ownership And Dominion In The Lands Of The Maya, Maya America Editors

Maya America: Journal of Essays, Commentary, and Analysis

Editors' introduction of Maya America Volume 5 Issue 2


Complete Issue: Volume 5 Issue 2, Maya America Editors Dec 2023

Complete Issue: Volume 5 Issue 2, Maya America Editors

Maya America: Journal of Essays, Commentary, and Analysis

The full Issue 2, Volume 5 of Maya America, published December 2023


Understanding The State Agency Policies Toward Rap Usage In The United States: State Of Practice, Ayman Ali, Venkatsushanth Revelli Dec 2023

Understanding The State Agency Policies Toward Rap Usage In The United States: State Of Practice, Ayman Ali, Venkatsushanth Revelli

Henry M. Rowan College of Engineering Departmental Research

The usage of Reclaimed Asphalt Pavement (RAP) material is a highly resource-conservative, economical, and sustainable practice in flexible pavement construction. However, its usage in hot mix asphalt (HMA) is capped at 25% by the majority of state transportation agencies due to its aging levels, stiffness characteristics, and handling capabilities, which may result in early-age pavement distress. Though researchers suggest methodologies to increase RAP usage, higher RAP percentages in asphalt pavements require the support of state authorities. The main objective of this paper is to provide information on how different states design their mixtures with high RAP percentages. This study reviewed …


Striking Up The Band, Eric F. Spina Dec 2023

Striking Up The Band, Eric F. Spina

President's Blog: From the Heart

The Flyer Pep Band and Pride of Dayton Marching Band are all about sounding the Flyer spirit loudly and proudly at home and on the national stage.


Lesion Detection In Women Breast’S Dynamic Contrast-Enhanced Magnetic Resonance Imaging Using Deep Learning, Sudarshan Saikia, Tapas Si, Darpan Deb, Kangkana Bora, Saurav Mallik, Ujjwal Maulik, Zhongming Zhao Dec 2023

Lesion Detection In Women Breast’S Dynamic Contrast-Enhanced Magnetic Resonance Imaging Using Deep Learning, Sudarshan Saikia, Tapas Si, Darpan Deb, Kangkana Bora, Saurav Mallik, Ujjwal Maulik, Zhongming Zhao

Faculty, Staff and Student Publications

Breast cancer is one of the most common cancers in women and the second foremost cause of cancer death in women after lung cancer. Recent technological advances in breast cancer treatment offer hope to millions of women in the world. Segmentation of the breast's Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) is one of the necessary tasks in the diagnosis and detection of breast cancer. Currently, a popular deep learning model, U-Net is extensively used in biomedical image segmentation. This article aims to advance the state of the art and conduct a more in-depth analysis with a focus on the use …


University Faculty Perceptions Of Professional Development: Impact And Effectiveness, Claudia Vela, Velma D. Menchaca, Hilda Silva Dec 2023

University Faculty Perceptions Of Professional Development: Impact And Effectiveness, Claudia Vela, Velma D. Menchaca, Hilda Silva

Journal of Educational Leadership in Action

The purpose of this study was to examine faculty perceptions of the effectiveness and impact of professional development programs and activities in the areas of teaching, research, and service. This qualitative phenomenological study was conducted in a four-year Hispanic-serving institution in South Texas. It focused on exploring tenured and tenure-track faculty perceptions and experiences of their participation in professional development to help them meet tenure and promotion expectations. Analysis of data showed that faculty had mixed feelings about the workshops and training sessions that were offered on campus. However, networking, collaboration, and access to resources and technology were practices that …


High-Throughput Deconvolution Of 3d Organoid Dynamics At Cellular Resolution For Cancer Pharmacology With Cellos., Patience Mukashyaka, Pooja A Kumar, David J Mellert, Shadae Nicholas, Javad Noorbakhsh, Mattia Brugiolo, Elise T Courtois, Olga Anczuków, Edison Liu, Jeffrey Chuang Dec 2023

High-Throughput Deconvolution Of 3d Organoid Dynamics At Cellular Resolution For Cancer Pharmacology With Cellos., Patience Mukashyaka, Pooja A Kumar, David J Mellert, Shadae Nicholas, Javad Noorbakhsh, Mattia Brugiolo, Elise T Courtois, Olga Anczuków, Edison Liu, Jeffrey Chuang

Faculty Research 2023

Three-dimensional (3D) organoid cultures are flexible systems to interrogate cellular growth, morphology, multicellular spatial architecture, and cellular interactions in response to treatment. However, computational methods for analysis of 3D organoids with sufficiently high-throughput and cellular resolution are needed. Here we report Cellos, an accurate, high-throughput pipeline for 3D organoid segmentation using classical algorithms and nuclear segmentation using a trained Stardist-3D convolutional neural network. To evaluate Cellos, we analyze ~100,000 organoids with ~2.35 million cells from multiple treatment experiments. Cellos segments dye-stained or fluorescently-labeled nuclei and accurately distinguishes distinct labeled cell populations within organoids. Cellos can recapitulate traditional luminescence-based drug response …


Physically And Chemically‑Crosslinked L‑Arginine‑Loaded Polyvinyl Alcohol‑ Hyaluronic Acid‑ Cellulose Nanocrystals Hydrogel Membranes For Wound Healing: Influence Of Crosslinking Methods On Biological Performance Of Membranes In‑Vitro, Elbadawy A. Kamoun, Elbadawy A. Kamoun Dec 2023

Physically And Chemically‑Crosslinked L‑Arginine‑Loaded Polyvinyl Alcohol‑ Hyaluronic Acid‑ Cellulose Nanocrystals Hydrogel Membranes For Wound Healing: Influence Of Crosslinking Methods On Biological Performance Of Membranes In‑Vitro, Elbadawy A. Kamoun, Elbadawy A. Kamoun

Nanotechnology Research Centre

Two types of polyvinyl alcohol-blended hyaluronic acid and cellulose nanocrystals (PVA/HA/CNCs) hydrogels membranes were developed as delivery agents for L-arginine using chemical/and/physical crosslinking methods for exploring biological performance of the obtained membranes. Chemically and physically/crosslinked membranes were fabricated by solution-casting and freeze-thawing techniques, respectively. The characterization of the crosslinked PVA/HA/CNCs/Larginine membranes were conducted by SEM, FTIR, TGA, swelling ratio, and in—vitro L-arginine release. Furthermore, applying two types of crosslinked membranes in vitro were investigated in terms of cytotoxicity, hemocompatibility, and cell adhesion affinity of HFB-4 cell line. Chemical and physical-crosslinked membranes were verified through the esterification and hydrogen bonds interactions, …


Predicting Speaking Proficiency With Fluency Features Using Machine Learning, Ethan D. Erickson Dec 2023

Predicting Speaking Proficiency With Fluency Features Using Machine Learning, Ethan D. Erickson

Theses and Dissertations

This study investigates the interplay between temporal fluency measures, self-assessment, and language proficiency scores in novice- to intermediate- level language learners of Spanish and French. Analyzing data from 163 participants, the research employs both traditional linear regression and advanced XGBoost machine learning models. Findings demonstrate a moderate positive correlation between self-assessment and Oral Proficiency Interview by Computer (OPIc) scores, underscoring the dependable self-awareness of learners. Notably, XGBoost performs as well as linear regression in predicting OPIc scores and has more potential, underlining the efficacy of advanced methodologies. The study identifies Mean Length of Utterance (MLU) as a crucial predictor, highlighting …


Impacts Of Artificial Light At Night On The Early Life History Of Two Ecosystem Engineers, Svenja Tidau, Fraser T. Brough, Luis Gimenez, Stuart R. Jenkins, Thomas W. Davies Dec 2023

Impacts Of Artificial Light At Night On The Early Life History Of Two Ecosystem Engineers, Svenja Tidau, Fraser T. Brough, Luis Gimenez, Stuart R. Jenkins, Thomas W. Davies

School of Biological and Marine Sciences

Sessile marine invertebrates play a vital role as ecosystem engineers and in benthic-pelagic coupling. Most benthic fauna develop through larval stages and the importance of natural light cycles for larval biology and ecology is long-established. Natural light-dark cycles regulate two of the largest ocean-scale processes that are fundamental to larvae’s life cycle: the timing of broadcast spawning for successful fertilisation and diel vertical migration for foraging and predator avoidance. Given the reliance on light and the ecological role of larvae, surprisingly little is known about the impacts of artificial light at night (ALAN) on the early life history of habitat-forming …


Machine Learning And Metabolic Model Guided Crispri Reveals A Central Role For Phosphoglycerate Mutase In Chlamydia Trachomatis Persistence, Niaz Bahar Chowdhury, Nick Pokorzynski, Elizabeth A. Rucks, Scot P. Ouellette, Rey A. Carabeo, Rajib Saha Dec 2023

Machine Learning And Metabolic Model Guided Crispri Reveals A Central Role For Phosphoglycerate Mutase In Chlamydia Trachomatis Persistence, Niaz Bahar Chowdhury, Nick Pokorzynski, Elizabeth A. Rucks, Scot P. Ouellette, Rey A. Carabeo, Rajib Saha

Department of Chemical and Biomolecular Engineering: Faculty Publications

Upon nutrient starvation, Chlamydia trachomatis serovar L2 (CTL) shifts from its normal growth to a non-replicating form, termed persistence. It is unclear if persistence is an adaptive response or lack of it. To understand that transcriptomics data were collected for nutrientsufficient and nutrient-starved CTL. Applying machine learning approaches on transcriptomics data revealed a global transcriptomic rewiring of CTL under stress conditions without having any global stress regulator. This indicated that CTL’s stress response is due to lack of an adaptive response mechanism. To investigate the impact of this on CTL metabolism, we reconstructed a genome-scale metabolic model of CTL (iCTL278) …


2023 In Review: Points Of Pride, Reporter Staff Dec 2023

2023 In Review: Points Of Pride, Reporter Staff

Browse All News

No abstract provided.


Engineering E. Coli Strains Using Antibiotic-Resistance-Gene-Free Plasmids, Matthew B Amrofell, Sunaina Rengarajan, Steven T Vo, Erick S Ramirez Tovar, Larissa Lobello, Gautam Dantas, Tae Seok Moon Dec 2023

Engineering E. Coli Strains Using Antibiotic-Resistance-Gene-Free Plasmids, Matthew B Amrofell, Sunaina Rengarajan, Steven T Vo, Erick S Ramirez Tovar, Larissa Lobello, Gautam Dantas, Tae Seok Moon

2020-Current year OA Pubs

We created a generalizable pipeline for antibiotic-resistance-gene-free plasmid (ARGFP)-based cloning using a dual auxotrophic- and essential-gene-based selection strategy. We use auxotrophic selection to construct plasmids in engineered E. coli DH10B cloning strains and both auxotrophic- and essential-gene-based selection to (1) select for recombinant strains and (2) maintain a plasmid in E. coli Nissle 1917, a common chassis for engineered probiotic applications, and E. coli MG1655, the laboratory "wild-type" E. coli strain. We show that our approach has comparable efficiency to that of antibiotic-resistance-gene-based cloning. We also show that the double-knockout Nissle and MG1655 strains are simple to transform with plasmids …


Miocene Climatic Optimum Fungal Record And Plant-Based Crest Climatic Reconstruction From Southern Mcmurdo Sound, Antarctica, Mallory Pilie, Martha E. Gibson, Ingrid C. Romero, Noelia B.Nuñez Otaño, Matthew J. Pound, Jennifer M.K. O'Keefe, Sophie Warny Dec 2023

Miocene Climatic Optimum Fungal Record And Plant-Based Crest Climatic Reconstruction From Southern Mcmurdo Sound, Antarctica, Mallory Pilie, Martha E. Gibson, Ingrid C. Romero, Noelia B.Nuñez Otaño, Matthew J. Pound, Jennifer M.K. O'Keefe, Sophie Warny

Faculty Publications

Deep-time palynological studies are necessary to evaluate plant and fungal distribution under warmer-than-present scenarios such as those of the Middle Miocene. Previous palynological studies from southern McMurdo Sound, Antarctica (SMS), have provided unique documentation for Neogene environments in the Ross Sea region during a time of pronounced global warming. The present study builds on these studies and provides a new climate reconstruction using the previously published SMS pollen and plant spore data. Additionally, 44 SMS samples were reanalyzed with a focus on the fungal fraction of the section to evaluate the fungal distribution under warmer than present conditions. The probability-based …