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Faculty Senate Executive Committee Minutes December 11, 2023, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Call to Order - Maureen Hearns
• University Business - Elizabeth Cantwell, President | Larry Smith, Provost
• Faculty Senate Business - Maureen Hearns | John Ferguson | Grant Cardon
• Information
• Reports
• Old Business
• New Business
• Adjourn: 4:13 pm

The Versatile Virgin Mary, Emma Donnelly

Marian Library Blog Archive

Through Our Lady of Guadalupe, Mary shows us that she is constantly revealing herself to us in a variety of ways … if we are open to seeing her.

Turnstile File Transfer: A Unidirectional System For Medium-Security Isolated Clusters, Mark Monnin, Lori L. Sussman

Journal of Cybersecurity Education, Research and Practice

Data transfer between isolated clusters is imperative for cybersecurity education, research, and testing. Such techniques facilitate hands-on cybersecurity learning in isolated clusters, allow cybersecurity students to practice with various hacking tools, and develop professional cybersecurity technical skills. Educators often use these remote learning environments for research as well. Researchers and students use these isolated environments to test sophisticated hardware, software, and procedures using full-fledged operating systems, networks, and applications. Virus and malware researchers may wish to release suspected malicious software in a controlled environment to observe their behavior better or gain the information needed to assist their reverse engineering processes. …

Engineering Exosomes To Specifically Target The Mitochondria Of Brain Cells, Xin Yan, Xinqian Chen, Zhiying Shan, Lanrong Bi

Michigan Tech Publications

Mitochondrial dysfunction is associated with various health conditions, including cardiovascular and neurodegenerative diseases. Mitochondrial-targeting therapy aims to restore or enhance mitochondrial function to treat or alleviate these conditions. Exosomes, small vesicles that cells secrete, containing a variety of biomolecules, are critical in cell-to-cell communication and have been studied as potential therapeutic agents. Exosome-based therapy has the potential to treat both cardiovascular and neurodegenerative diseases. Combining these two approaches involves using exosomes as carriers to transport mitochondrial-targeting agents to dysfunctional or damaged mitochondria within target cells. This article presents a new technique for engineering brain-derived exosomes that target mitochondria and has …

Residential Indoor Air Quality Study – Assessment And Mitigation, Giovanni Cerrato

Mechanical Engineering Theses

An increased awareness in residential indoor air quality (IAQ) has led to an increase in technologies that assist in improving IAQ. Two such technologies include Electro-static (ES) air cleaners and Photocatalytic Oxidizing (PCO) air cleaners. ES air cleaners remove particulate matter from indoor air, but are known to emit ozone, a contaminant, as a by-product. PCO air cleaners abate gaseous pollutants (i.e., Volatile Organic Compounds, VOCs); however, a lack of testing standards creates confusion about their effectiveness in improving IAQ in a real residential home. On the other hand, environmental variables such as temperature and humidity were found to affect …

12.11.2023 Orsp Connect, Liz Williamson

ORED Newsletter

December 11, 2023 Newsletter

Information Communication Technology Competence And Reference Service Provision In Federal Universities In North-Central Nigeria., Ezinwanyi Madukoma, Catherine Enatta Ikokoh

Library Philosophy and Practice (e-journal)

The study investigates information communication technology competence and reference service provision in Federal Universities in North-Central, Nigeria. Reference librarians now provide users with databases that give access to millions of journal articles as well as access to the internet which has holdings of libraries and a limitless variety of formal and informal sources of information. The study has one objective, a research question and one hypothesis. The study adopted total enumeration using a descriptive survey design. The population of the study is three hundred and sixty library personnel comprising professionals and para-professionals. Three hundred and six questionnaires were returned and …

Examining Faculty Transformational Leadership Style And University Sophomores’ Institutional Commitment, Olusegun Oladayo Kuteyi

Walden Dissertations and Doctoral Studies

No abstract provided.

Evaluation Of Various Turbulence Models For Turbulent Separated Flow Over A Model Two-Dimensional Bump, Xuehui Qian

Mechanical Engineering and Materials Science Independent Study

In this paper, performance of several turbulence models is evaluated by computing the turbulent separated flow over a 2D bump using the RANS equations. The turbulence models considered are the Spalart-Allmaras (SA), SST k-ω, and Wray-Agarwal (WA) models. The geometry of the 2D bump is the centerline geometry of the NASA/Virginia Tech (VT) 3D BeVERLI hill bump. Since the experimental data is available only for the 3D bump, the goal of this paper is to compare the numerical solutions using the three turbulence models on a series of grids from coarse to fine. The experimental data of the 3D bump …

Acid Attack: How Escherichia Coli Strains Resist Acid Stress, Lindsey Miller

Honors Theses

The systems used by Escherichia coli to combat heightened levels of acidity within their environment are varied and complex. Four distinct systems used by E. coli to resist acid-induced stress were identified in 2004 by Foster (1), though six now are known today. These systems include the glucose-repressed, glutamate-dependent, arginine-dependent, lysine-dependent, ornithine-dependent, and serine-dependent acid resistance systems. Each system is also known by its corresponding abbreviation, AR1-AR6. What is known about each system varies due to identification date, complexity of the pathway, and amount of research completed. Within this paper, each system will be identified and the pathway defined, combining …

Florist: (Ar System), Yanran Ding

Theses

The "Florist (AR system)" envisions a novel application of Augmented Reality (AR) in floral design, aimed at harmonizing traditional floristry with the digital age. While the full system is not yet realized, the conceptual design presents a compelling visual and interactive blueprint. It anticipates a platform that educates and assists users in crafting personalized floral arrangements through a rich database, AR tutorials, and customization features. This conceptual framework promises to address common barriers in flower arrangement by fostering an accessible, usercentered experience that could transform the floristry landscape.

Cookool: A Futuristic Cooking Innovation, Guannan Ling

Theses

Cookool is a futuristic innovation project that utilizes real-time interactive design and technology to display cooking information seamlessly, aiming to create a cool, friendly, and relaxed cooking experience for everyone to try, learn, and fall in love with. In traditional kitchens, people often face various challenges such as choosing dishes and controlling temperatures. However, in the future, our kitchen will leverage AI technology to precisely recommend dishes based on personal preferences, utilize thermal detection to monitor utensil temperatures, and leverage hologram and AR technology to showcase recipes and cooking processes, making cooking simpler. Yet, technology alone cannot create an inclusive …

Impact Of Irrigation On Vulnerability Of Winter Wheat Under Extreme Climate Change Scenario: A Case Study Of North China Plain, Yulian Gao, Lin Wang, Yaojie Yue

Department of Agricultural and Biological Systems Engineering: Faculty Publications

An inadequate understanding of the impacts of adaptation countermeasures tends to exaggerate the adverse e􀀀ects of climate change on agricultural systems. Motivated by proposing reasonable climate change adaptation countermeasures, the present study applied the EPIC model to quantify the impacts of climate change and irrigation changes with future socioeconomic development on agricultural production. Winter wheat yield losses using dynamic irrigation parameters in the North China Plain (NCP) from 2010 to 2099 under a scenario coupling climate change and future socioeconomic development (RCP8.5-SSP3), and those under an extreme climate change scenario (RCP8.5), were simulated. Results show that EPIC model demonstrates superior …

Enlightenment Ideals And Belief In Progress In The Run-Up To The Industrial Revolution: A Textual Analysis, Ali Almelhem, Murat Iyigun, Austin Kennedy, Jared Rubin

ESI Working Papers

We trace the evolution of the language of science, religion, and political economy in the centuries leading to the British Industrial Revolution. Using textual analysis of 264,443 works printed in England between 1500 and 1900, we test whether British culture manifested a belief in progress associated with science and industry. Our analysis yields three main findings. First, there was a separation in the languages of science and religion beginning in the mid-18th century. Second, volumes using language at the nexus of science and political economy became more progress-oriented during the Enlightenment. Third, volumes using industrial language—especially those at the science-political …

Taxane-Based Chemotherapy Is Effective In Metastatic Appendiceal Adenocarcinoma, Julia Dansby, Aditya More, Mohammad Zeineddine, Abdelrahman Yousef, Alisha Bent, Farshid Dayyani, Robert Wolff, Michael Overman, John Paul Shen

Faculty, Staff and Student Publications

Appendiceal cancer is a rare, orphan disease with no therapies currently approved by the FDA for its treatment. Given the limited data regarding drug efficacy, these tumors have historically been treated with chemotherapy designed for colon cancer. However, an overwhelming body of molecular data has demonstrated that appendiceal adenocarcinoma is a distinct entity with key molecular differences from colon cancer, notably rare APC mutation. Recognizing that APC loss-of-function is thought to contribute to taxane resistance and that taxanes are effective in the treatment of other gastrointestinal tumors, including gastric, esophageal, and small bowel adenocarcinoma, we completed a single-center retrospective study …

Sustained Disease Control In Immune Checkpoint Blockade Responders With Microsatellite Instability-High Colorectal Cancer After Treatment Termination, Kristen Simmons, Jane V Thomas, Kaysia Ludford, Jason A Willis, Victoria S Higbie, Kanwal P S Raghav, Benny Johnson, Arvind Dasari, Bryan K Kee, Christine M Parseghian, Michael S Lee, Phat H Le, Maria P Morelli, John Paul Shen, Alisha Bent, Eduardo Vilar, Robert A Wolff, Scott Kopetz, Michael J Overman, Van Karlyle Morris

Faculty, Staff and Student Publications

Immune checkpoint inhibitors improve survival in patients with mismatch repair deficiency/microsatellite instability-high (MSI-H) colorectal cancer. The recurrence outcomes following discontinuation of immunotherapy after prolonged disease control have not been definitively reported in large series. Records from patients with advanced MSI-H colorectal cancer from The University of Texas - MD Anderson Cancer Center who received immunotherapy between 2014 and 2022 and stopped after prolonged clinical benefit were reviewed. Median progression-free and overall survival were estimated. Associations between the event of recurrence and coexisting mutations (KRAS/NRAS, BRAFV600E), metastatic organ involvement (lung, liver, lymph node, or peritoneum), metastatic timing (synchronous vs. metachronous), prior …

The Representation Of Third-Party Helping Interactions In Infancy, Laura Schlingloff-Nemecz, Denis Tatone, Gergely Csibra

School of Psychology

Despite numerous findings on the sophisticated inferences that human infants draw from observing third-party helping interactions, currently there is no theoretical account of how infants come to understand such events in the first place. After reviewing the available evidence in infants, we describe an account of how human adults understand helping actions. According to this mature concept, helping is a second-order, goal-directed action aiming to increase the utility of another agent (the Helpee) via reducing the cost, or increasing the reward, of the Helpee's own goal-directed action. We then identify the cognitive prerequisites for conceiving helping in this way and …

High-Fidelity Large-Diversity Monoclonal Mammalian Cell Libraries By Cell Cycle Arrested Recombinase-Mediated Cassette Exchange, Chuan Chen, Zening Wang, Minhyo Kang, Ki Baek Lee, Xin Ge

Faculty, Staff and Student Publications

Mammalian cells carrying defined genetic variations have shown great potentials in both fundamental research and therapeutic development. However, their full use was limited by lack of a robust method to construct large monoclonal high-quality combinatorial libraries. This study developed cell cycle arrested recombinase-mediated cassette exchange (aRMCE), able to provide monoclonality, precise genomic integration and uniform transgene expression. Via optimized nocodazole-mediated mitotic arrest, 20% target gene replacement efficiency was achieved without antibiotic selection, and the improved aRMCE efficiency was applicable to a variety of tested cell clones, transgene targets and transfection methods. As a demonstration of this versatile method, we performed …

Finding Ideal Parameters For Recycled Material Fused Particle Fabrication-Based 3d Printing Using An Open Source Software Implementation Of Particle Swarm Optimization, Shane Oberloier, Nicholas G. Whisman, Joshua M. Pearce

Michigan Tech Publications

As additive manufacturing rapidly expands the number of materials including waste plastics and composites, there is an urgent need to reduce the experimental time needed to identify optimized printing parameters for novel materials. Computational intelligence (CI) in general and particle swarm optimization (PSO) algorithms in particular have been shown to accelerate finding optimal printing parameters. Unfortunately, the implementation of CI has been prohibitively complex for noncomputer scientists. To overcome these limitations, this article develops, tests, and validates PSO Experimenter, an easy-to-use open-source platform based around the PSO algorithm and applies it to optimizing recycled materials. Specifically, PSO Experimenter is used …

Micromagnetic Investigation Of The Dynamics Of Domain Walls And Substructures In Non-Uniform Magnetic Thin Films, Trae Staggers

Electronic Theses and Dissertations Archive

Since the discovery of gigantic magnetoresistance and the advent of spintronics, magnetic materials have become ubiquitous in modern technology. As such, a wide range of research areas within this field are being continuously explored for potential means to improve device scaling, decrease energy consumption, or increase speed, as well as to understand the fundamental physics governing spin order at the micro- and nanoscale. One of the avenues under current investigation involves the use of the spin-orbit interaction in systems with broken inversion symmetry through the introduction of interfaces or compositional variations. I will introduce the theory of micromagnetism and demonstrate …

Advanced Diffusion Mri Technique And Applications In Placenta And Brain, Zhexian Sun

McKelvey School of Engineering Graduate Student Theses & Dissertations

Among a series of contrasts of MRI, diffusion MRI (dMRI) is different from conventional MRI by its ability to capture information about the random movement of water molecules and their interaction with local tissue microstructures. This capability holds the potential to reveal intricate subvoxel microstructural information linked to pathological changes, offering potential imaging biomarkers. A higher-order diffusion analysis model helps to yield more accurate and specific parameters but requires more extensive parameter tuning and higher image quality. In this study, we firstly fine-tuned the previously developed diffusion basis spectrum imaging (DBSI) method to strike a balance between efficiency and accuracy …

Uni New Horizons Band Concert, December 11, 2023 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recitals given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Exploring Policies & Practices For The Private Sector To Advance Women’S Economic Empowerment And Prevent Gender Based Violence In Post-Conflict Countries, Amina Helal

Theses and Dissertations

This study aims to investigate the role of the private sector in advancing women’s economic empowerment and gender-based violence prevention with a focus on post-conflict countries. It explores challenges facing them, and opportunities to be seized by governments and other stakeholders in this regard. The study also sheds light on the gap in the private sector’s awareness and commitment to achieve the UN Sustainable Development Goals (SDGs) and to implement the UN Women, Peace and Security (WPS) agenda in post-conflict countries. It explores the different possible engagements of the private sector in response to the research question. The thesis also …

Public Mental Health Through Social Media In The Post Covid-19 Era, Deepika Sharma, Jaiteg Singh, Babar Shah, Farman Ali, Ahmad Ali Alzubi, Mallak Ahmad Alzubi

All Works

Social media is a powerful communication tool and a reflection of our digital environment. Social media acted as an augmenter and influencer during and after COVID-19. Many of the people sharing social media posts were not actually aware of their mental health status. This situation warrants to automate the detection of mental disorders. This paper presents a methodology for the detection of mental disorders using micro facial expressions. Micro-expressions are momentary, involuntary facial expressions that can be indicative of deeper feelings and mental states. Nevertheless, manually detecting and interpreting micro-expressions can be rather challenging. A deep learning HybridMicroNet model, based …

Synaptic Plasticity Emulation By Natural Biomaterial Honey-Cnt-Based Memristors, Zoe Templin, Md Mehedi Hasan Tanim, Feng Zhao

Electrical and Computer Engineering Faculty Research & Creative Works

Artificial synaptic devices made from natural biomaterials capable of emulating functions of biological synapses, such as synaptic plasticity and memory functions, are desirable for the construction of brain-inspired neuromorphic computing systems. The metal/dielectric/metal device structure is analogous to the pre-synapse/synaptic cleft/post-synapse structure of the biological neuron, while using natural biomaterials promotes ecologically friendly, sustainable, renewable, and low-cost electronic devices. In this work, artificial synaptic devices made from honey mixed with carbon nanotubes, honey-carbon nanotube (CNT) memristors, were investigated. The devices emulated spike-timing-dependent plasticity, with synaptic weight as high as 500%, and demonstrated a paired-pulse facilitation gain of 800%, which is …

Metformin: A Potential Treatment For Acne, Hidradenitis Suppurativa And Rosacea, Minah Cho, Yu Ri Woo, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim

Faculty, Staff and Student Publications

Metformin is a widely used drug for treatment of diabetes mellitus, due to its safety and efficacy. In addition to its role as an antidiabetic drug, numerous beneficial effects of metformin have enabled its use in various diseases. Considering the anti-androgenic, anti-angiogenic, anti-fibrotic and antioxidant properties of metformin, it may have the potential to improve chronic inflammatory skin diseases. However, further evidence is needed to confirm the efficacy of metformin in dermatological conditions, This review focuses on exploring the therapeutic targets of metformin in acne vulgaris, hidradenitis suppurativa and rosacea, by studying their pathogeneses.

Teaching Engineering Design-Based Integrated Stem In Rural Contexts: Nurturing Future Designers, Jung Han, Euisuk Sung, Todd Kelley, John Geoffrey Knowles

Publications and Research

There is a notable shift towards prioritizing the teaching of engineering design within K-12 education, coupled with a strong recommendation for engineering design-based integrated STEM education. This approach underscores the sharing of science and engineering practices as a means to facilitate the learning of various STEM disciplines. Nonetheless, the implementation of integrated STEM education in rural schools poses challenges due to constrained resources and a shortage of high-quality programs. To present a tangible instance of design-based integrated STEM education within a rural setting, this study presents a model lesson that showcases the integration of interdisciplinary problem-solving skills within a genuine …

Immunoproximity Biotinylation Reveals The Axon Initial Segment Proteome, Wei Zhang, Yu Fu, Luxin Peng, Yuki Ogawa, Xiaoyun Ding, Anne Rasband, Xinyue Zhou, Maya Shelly, Matthew N Rasband, Peng Zou

Faculty, Staff and Students Publications

The axon initial segment (AIS) is a specialized neuronal compartment required for action potential generation and neuronal polarity. However, understanding the mechanisms regulating AIS structure and function has been hindered by an incomplete knowledge of its molecular composition. Here, using immuno-proximity biotinylation we further define the AIS proteome and its dynamic changes during neuronal maturation. Among the many AIS proteins identified, we show that SCRIB is highly enriched in the AIS both in vitro and in vivo, and exhibits a periodic architecture like the axonal spectrin-based cytoskeleton. We find that ankyrinG interacts with and recruits SCRIB to the AIS. However, …

Allelic Strengths Of Encephalopathy-Associated Uba5 Variants Correlate Between In Vivo And In Vitro Assays, Xueyang Pan, Albert N Alvarez, Mengqi Ma, Shenzhao Lu, Michael W Crawford, Lauren C Briere, Oguz Kanca, Shinya Yamamoto, David A Sweetser, Jenny L Wilson, Ruth J Napier, Jonathan N Pruneda, Hugo J Bellen

Faculty, Staff and Students Publications

Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and endoplasmic reticulum stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder characterized by early-onset encephalopathy, movement abnormalities, global developmental delay, intellectual disability, and seizures. DEE44 is caused by at least 12 different missense variants described as loss of function (LoF), but the relationships between genotypes and molecular or clinical phenotypes remain to be established. We developed a humanized UBA5 fly model and biochemical activity assays in order to describe in vivo and in vitro genotype–phenotype relationships …

Engineering Exosomes To Specifically Target The Mitochondria Of Brain Cells, Xin Yan, Xinqian Chen, Zhiying Shan, Lanrong Bi

Michigan Tech Publications

Mitochondrial dysfunction is associated with various health conditions, including cardiovascular and neurodegenerative diseases. Mitochondrial-targeting therapy aims to restore or enhance mitochondrial function to treat or alleviate these conditions. Exosomes, small vesicles that cells secrete, containing a variety of biomolecules, are critical in cell-to-cell communication and have been studied as potential therapeutic agents. Exosome-based therapy has the potential to treat both cardiovascular and neurodegenerative diseases. Combining these two approaches involves using exosomes as carriers to transport mitochondrial-targeting agents to dysfunctional or damaged mitochondria within target cells. This article presents a new technique for engineering brain-derived exosomes that target mitochondria and has …