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Knowledge And Performance On Diabetes Control Among Primary Health Workers: A Baseline Survey Of Quasi Experimental Study In Naypyitaw, Myanmar, Kyi Thar, Sathirakorn Pongpanich, Min New Tun, Zaw Myo Aung

Journal of Health Research

Background: Diabetes is a growing public health problem. Due to a paradigm shift in diabetes control from hospitals to communities, improving the knowledge and performance of primary health care (PHC) providers with regards to diabetes is essential. Although Myanmar has a high prevalence of diabetes, the knowledge and performance of PHC providers has not been properly assessed before. This study assessed PHC knowledge and performance on diabetes control in two townships in Naypyitaw, Myanmar.

Methods: In this cross-sessional descriptive study, PHC providers, including midwives, lady health visitors (female nurse supervisors), and public health supervisors were selected. Their socio-demographic variables, as …

Volume 1, Issue 3, Bryant University

Bryant Bulldog Bulletin (2023-2024)

No abstract provided.

Homeostatic Synaptic Plasticity Of Miniature Excitatory Postsynaptic Currents In Mouse Cortical Cultures Requires Neuronal Rab3a, Andrew G. Koesters, Mark M. Rich, Kathrin L. Engisch

Biological Sciences Faculty Publications

Following prolonged activity blockade, amplitudes of miniature excitatory postsynaptic currents (mEPSCs) increase, a form of homeostatic plasticity termed “synaptic scaling.” We previously showed that a presynaptic protein, the small GTPase Rab3A, is required for full expression of the increase in miniature endplate current amplitudes following prolonged blockade of action potential activity at the mouse neuromuscular junction in vivo (Wang et al., 2011), but it is unknown whether this form of Rab3A-dependent homeostatic plasticity shares any characteristics with central synapses. We show here that synaptic scaling of mEPSCs is impaired in mouse cortical neuron cultures prepared from Rab3A-/- and Rab3A Earlybird …

Association Between Lgb Status And Levels Of Mental Distress, Florida Brfss 2017-2019, Tammie M. Johnson, Torhonda Lee

Florida Public Health Review

Background: Poor mental health is a significant determinant of health in the US and is associated with several adverse health outcomes. Health-Related Quality of Life (HRQOL) measures help assess the mental distress burden on individuals and populations. This study examines mental distress health disparities at and above the frequent mental distress threshold among Florida adults who identify as lesbian, gay, or bisexual (LGB).

Methods: We used data from the 2017-2019 Florida Behavioral Risk Factor Surveillance System (BRFSS). A total of 39,876 adults aged 18 years and older were included in the analyses. The key dependent variables used for the study …

Instructors At A Crossroad: Perceptions Of Collaboration And Support Intersect With Intentions To Implement A Cure, Justin Berl

Dissertations and Theses

An ongoing crisis of student drop-off from undergraduate science, technology, engineering and mathematics (STEM) education has led to a sustained call over the last 15+ years for the increased implementation of updated practices in undergraduate STEM education. Though over the past few decades many researchers have developed and analyzed the efficacy of various evidence-based teaching practices (EBTPs) designed to improve the state of undergraduate STEM education throughout the country, the rate at which these EBTPs are implemented in undergraduate STEM classrooms remains low.

In order to better understand the specific factors that affect individual instructors' efforts to implement EBTPs, we …

The Biomechanics Of Tooth Strength In Australopiths, Rachel Sender

Arts & Sciences Graduate Student Theses and Dissertations

Teeth must fracture foods while avoiding being fractured themselves. This dissertation consists of three studies aimed at assessing adaptations of molars that may confer biomechanical strength against certain types of diet. The first study evaluates dome biomechanical models used to describe tooth strength. The second study tested the hypothesis that australopith molars, which have enlarged molars and thick enamel, are mechanically strong and well adapted to withstand high bite forces. The third study tested biomechanical predictions derived from experiments performed on a dome model that examined how tooth strength changes at progressive stages of wear under loading regimes representing different …

The Grizzly, September 14, 2023, Marie Sykes, Erin Corcoran, Kate Horan, Amelia Kunko, Andrew J. Perez, Mairead Mcdermott, Renie Christensen, Hannah Conley, Sean Mcginley, Georgia Gardner, Adam Denn, Dominic Minicozzi

Ursinus College Grizzly Newspaper, 1978 to Present

Good Samaritan Policy Changes: Good Ideas? • Changes Across Wismer • Student Handbook Changes • Letter From the Editor • Hello From the News Editor • ODA's Peer Mentor Program • Meet SGA President: Ben Douglas • Opinions: Upper Wismer's Wonderful New Eats • Editor Introductions • UC Soccer on Fire! • Bears' Football Comes Out of Hibernation With a Head of Steam

Combining Expert Opinions To Assess Risk Of Change In Earth Systems: Permafrost Collapse, Global Wildfire, And Water Security, Sayedeh Sara Sayedi

Theses and Dissertations

In a world of uncertainty and change, leaders should base their decisions on best available scientific evidence. However, history has shown that science is often inadequately incorporated into the decision-making process. This dissertation investigates three environmental issues to identify the challenges of considering Earth system dynamics in policymaking and management. I also propose solutions for improving the two-way exchange of knowledge and values between researchers and policymakers. In chapter one, I investigate subsea permafrost carbon sensitivity to climate change using an expert assessment. The analysis revealed that subsea permafrost contains significant carbon stocks and is already contributing to climate change …

Exploring Relationships Between Psychological Capital And Perceived Stress Among Newly Graduated Nurses, Rita J. Jarvis-Isaac

Dissertations

Stress among the newly graduated nurses has been linked to physical and emotional distress, high turnover rates, and the quality of patient care. Psychological capital is a positive state of mind that consists of four components (hope, efficacy, resilience, and optimism). Higher levels of psychological capital have been linked to improvements in the work environment, and the psychological and emotional state of nurses. Despite the extensive work of researchers exploring psychological capital among nurses, its relationship to stress among new graduate nurses has not been well studied. The purpose of this quantitative, correlational study was to explore the relationship between …

Mettl14 Is A Chromatin Regulator Independent Of Its Rna N6-Methyladenosine Methyltransferase Activity, Xiaoyang Dou, Lulu Huang, Yu Xiao, Chang Liu, Yini Li, Xinning Zhang, Lishan Yu, Ran Zhao, Lei Yang, Chuan Chen, Xianbin Yu, Boyang Gao, Meijie Qi, Yawei Gao, Bin Shen, Shuying Sun, Chuan He, Jun Liu

Faculty, Staff and Student Publications

METTL3 and METTL14 are two components that form the core heterodimer of the main RNA m6A methyltransferase complex (MTC) that installs m6A. Surprisingly, depletion of METTL3 or METTL14 displayed distinct effects on stemness maintenance of mouse embryonic stem cell (mESC). While comparable global hypo-methylation in RNA m6A was observed in Mettl3 or Mettl14 knockout mESCs, respectively. Mettl14 knockout led to a globally decreased nascent RNA synthesis, whereas Mettl3 depletion resulted in transcription upregulation, suggesting that METTL14 might possess an m6A-independent role in gene regulation. We found that METTL14 colocalizes with the repressive H3K27me3 modification. Mechanistically, METTL14, but not METTL3, binds …

The Montclarion, September 14, 2023, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Rethinking Higher Education For The 4th Industrial Revolution: Synergetics In Global Social Transformations And Society Building, Danjoo N. Ghista, Ravi S. Sharma

All Works

This paper highlights the need for our Rethinking Education towards a global common good and cultivating New Era Universities for the 4th Industrial Revolution (4IR). 4IR represents a fundamental change in the way we live, work, and relate to one another. It is a new chapter in human development, enabled by extraordinary technological advances commensurate with those of the first, second, and third industrial revolutions. Indeed, the 4th Industrial Revolution measures up with the Post-Capitalist Society, involving policies catering to human living needs, enabling people to have a Neo-humanist outlook, and come together to form a universal and more evolved …

The Cowl - V. 88 N. 18 - September 14, 2023

The Cowl

The Cowl - student newspaper of Providence College. Vol. 88 No. 18 - September 14, 2023. 20 pages.

Development Of A Sensitive Microplate Assay For Characterizing Rna Methyltransferase Activity: Implications For Epitranscriptomics And Drug Development, Isaiah K. Mensah, Allison B. Norvil, Ming He, Emma Lendy, Nicole Hjortland, Hern Tan, Richard T. Pomerantz, Andrew Mesecar, Humaira Gowher

Department of Biochemistry and Molecular Biology Faculty Papers

RNA methylation is a ubiquitous post-transcriptional modification found in diverse RNA classes and is a critical regulator of gene expression. In this study, we used Zika virus RNA methyltransferase (MTase) to develop a highly sensitive microplate assay that uses a biotinylated RNA substrate and radiolabeled AdoMet coenzyme. The assay is fast, highly reproducible, exhibits linear progress-curve kinetics under multiple turnover conditions, has high sensitivity in competitive inhibition assays, and significantly lower background levels compared with the currently used method. Using our newly developed microplate assay, we observed no significant difference in the catalytic constants of the full-length nonstructural protein 5 …

2023-09-14 Institutional Animal Care And Use Committee Meeting Minutes, Morehead State University. Faculty Senate., Institutional Animal Care And Use Committee.

Faculty Senate Records

The meeting minutes of the Institutional Animal Care and Use Committee for September 14, 2023.

Speg Interactions That Regulate The Stability Of Excitation-Contraction Coupling Protein Complexes In Triads And Dyads, Chang Seok Lee, Sung Yun Jung, Rachel Sue Zhen Yee, Nadia H Agha, Jin Hong, Ting Chang, Lyle W Babcock, Jorie D Fleischman, Benjamin Clayton, Amy D Hanna, Christopher S Ward, Denise Lanza, Ayrea E Hurley, Pumin Zhang, Xander H T Wehrens, William R Lagor, George G Rodney, Susan L Hamilton

Faculty, Staff and Students Publications

Here we show that striated muscle preferentially expressed protein kinase α (Spegα) maintains cardiac function in hearts with Spegβ deficiency. Speg is required for stability of excitation-contraction coupling (ECC) complexes and interacts with esterase D (Esd), Cardiomyopathy-Associated Protein 5 (Cmya5), and Fibronectin Type III and SPRY Domain Containing 2 (Fsd2) in cardiac and skeletal muscle. Mice with a sequence encoding a V5/HA tag inserted into the first exon of the Speg gene (HA-Speg mice) display a >90% decrease in Spegβ but Spegα is expressed at ~50% of normal levels. Mice deficient in both Spegα and Speg β (Speg KO mice) …

N-Terminal Α-Amino Sumoylation Of Cofilin-1 Is Critical For Its Regulation Of Actin Depolymerization, Weiji Weng, Xiaokun Gu, Yang Yang, Qiao Zhang, Qi Deng, Jie Zhou, Jinke Cheng, Michael X Zhu, Junfeng Feng, Ou Huang, Yong Li

Faculty, Staff and Student Publications

Small ubiquitin-like modifier (SUMO) typically conjugates to target proteins through isopeptide linkage to the ε-amino group of lysine residues. This posttranslational modification (PTM) plays pivotal roles in modulating protein function. Cofilins are key regulators of actin cytoskeleton dynamics and are well-known to undergo several different PTMs. Here, we show that cofilin-1 is conjugated by SUMO1 both in vitro and in vivo. Using mass spectrometry and biochemical and genetic approaches, we identify the N-terminal α-amino group as the SUMO-conjugation site of cofilin-1. Common to conventional SUMOylation is that the N-α-SUMOylation of cofilin-1 is also mediated by SUMO activating (E1), conjugating (E2), …

History And Current Status Of Mediterranean Spotted Fever (Msf) In The Crimean Peninsula And Neighboring Regions Along The Black Sea Coast, Muniver T. Gafarova, Marina E. Eremeeva

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Mediterranean spotted fever (MSF) is a tick-borne rickettsiosis caused by Rickettsia conorii subspecies conorii and transmitted to humans by Rhipicephalus sanguineus ticks. The disease was first discovered in Tunisia in 1910 and was subsequently reported from other Mediterranean countries. The first cases of MSF in the former Soviet Union were detected in 1936 on the Crimean Peninsula. This review summarizes the historic information and main features of MSF in that region and contemporary surveillance and control efforts for this rickettsiosis. Current data pertinent to the epidemiology of the disease, circulation of the ticks and distribution of animal hosts are discussed …

Cardiovascular Disease And Stroke In Immune Ttp-Challenges And Opportunities, Senthil Sukumar, Marshall A Mazepa, Shruti Chaturvedi

Faculty, Staff and Students Publications

Advances in the management of immune thrombotic thrombocytopenic purpura (iTTP) have dramatically improved outcomes of acute TTP episodes, and TTP is now treated as a chronic, relapsing disorder. It is now recognized that iTTP survivors are at high risk for vascular disease, with stroke and myocardial infarction occurring at younger ages than in the general population, and cardiovascular disease is the leading cause of premature death in this population. iTTP appears to have a phenotype of accelerated vascular aging with a particular predilection for cerebral circulation, and stroke is much more common than myocardial infarction. In addition to traditional cardiovascular …

The Impact Of Home Confinement By Covid-19 On Mood State And Adaptive Behaviors In Spanish Swimmers, Jose Carlos Jaenes, David Alarcon Rubio, María José Arenilla-Villalba, Dominika Wilczyńska

Baltic Journal of Health and Physical Activity

Introduction: This study aimed to assess the mental condition of aquatic athletes during COVID-19 lockdowns and identify factors that could predict changes in their emotions and mood disturbances. Materials and Methods: The sample was composed of 506 competitive swimmers (ages 15-36) in four aquatic specializations, with 82.4% competing at the national level. Data was collected through questionnaires between April 10th and May 1st, 2020. Results: Female athletes had higher levels of unpleasant mood states and were generally more vulnerable to the lockdown's harmful effects. Team athletes had higher levels of friendliness, which may be a coping strategy for difficult situations. …

Broken Tails In Holstein Dairy Cattle: A Cross-Sectional Study, Hannah E. Olsen, Karly N. Anderson, Katherine C. Creutzinger, Kurt D. Vogel

Department of Animal Science: Faculty Publications

Dairy cows are regularly handled when moved to the milking parlor and during other routine procedures. Low-stress handling methods are important in avoiding negative welfare states for dairy cattle. Tail twisting is used by some handlers to prompt cattle movement. However, when used inappropriately with excessive force, tail twisting can lead to a broken tail. The aim of this cross-sectional study was to determine cow-level factors that may be associated with the prevalence of broken tails in dairy cattle. A subset of 229 Holstein dairy cows (68 primiparous and 161 multiparous) at a single dairy were assessed for broken tails …

Effects Of Photobiomodulation On High-Intensity Intermittent Anaerobic Performance Of Lower Limbs In Brazilian Jiu-Jitsu Athletes: A Randomized, Crossover, Double-Blind Clinical Trial., Rubens B. Dos Santos Junior, Bráulio H.M. Branco, Leonardo V. Andreato, Deborah C. S. Marques, Fabiano M. De Oliveira, Willian C. Ferreira, Eduardo M G Bardi, Eduardo V. Fernandes, Solange De Paula Ramos

International Journal of Exercise Science

International Journal of Exercise Science 16(6): 1165-1181, 2023. Photobiomodulation (PBM) has ergogenic effects on aerobic and anaerobic efforts and may improve sports performance. As Brazilian jiu-jitsu (BJJ) fighting requires both aerobic and anaerobic metabolism, so PBM may be effective in increasing the physical performance of BJJ athletes. Thus, this study aimed to verify the effects of PBM with different energy doses (6 or 12 J per point) on high-intensity intermittent anaerobic performance in BJJ athletes. Methods: Eleven male athletes performed three lower limb Wingate testing sessions. At the beginning of each session, in a randomized, crossover, double-blind fashion, the athletes …

Cardiovascular Responses To Unilateral, Bilateral, Upper, And Lower Limbs Resistance Exercises, Jean L. S. De Oliveira, Leonardo C. R. Lima, Renan V. Barreto, Witalo Kassiano, José De O. V. Neto, Júlio C. C. N. Filho, Túlio Banja, Robson S. De Matos, Cláudio De O. Assumpção

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 1154-1164, 2023. The effects of different resistance exercises on cardiovascular responses remain elusive. Therefore, the present study aimed to investigate acute cardiovascular responses to unilateral and bilateral upper and lower limb resistance exercise. Young healthy males (n = 22; 26.9 ± 5.4 years, 170.0 ± 6.0 cm, 77.0 ± 10.8 kg) participated in the present study. Four experimental sessions were carried out, each consisting of one of the four exercises: unilateral and bilateral knee extension, unilateral and bilateral biceps curl. Cardiovascular responses (heart rate; HR, systolic blood pressure; SBP, and rate-pressure product; RPP) …

Quality Of Cardiopulmonary Resuscitation Performed Over Hockey Shoulder Pads: A Simulation Study, Jennifer Longo, Katie J. Lyman, Thomas A. Hanson, Adam G. Estabrooks

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: Athletic trainers (ATs) must be prepared to manage cardiac arrest events in all athletes, including those participating in equipment-intensive sports. The goal of this study was to determine if first responders, specifically ATs, were able to perform high-quality cardiopulmonary resuscitation (CPR) over hockey shoulder pads. Methods: A sample of 50 ATs completed a one-minute, compression-only CPR proficiency test on a medium-fidelity manikin (Resusci Anne QCPR). Once deemed proficient, each participant completed CPR according to 2020 AHA guidelines on the manikin fitted with hockey shoulder pads for 8 minutes and 59 seconds. The primary measures of interest were the percentage …

Post-Activation Performance Enhancement Through Variable Loading Maintains Power Output Over Five Sets In Highly Trained Athletes, Robert Rocanelli, Morgan Siegel, Pedro Yunes, Pete Bommarito, Monique Mokha

Journal for Sports Neuroscience

The goal was to examine the acute effects of five sets of variable loading (VL) on the post-activation performance enhancement (PAPE) response during a live training session in highly trained athletes. PAPE is the phenomenon where acute improvements in power production in light loaded movements occur post near maximal loaded muscle contraction. PAPE may be induced with VL where resistance in the form of chains or bands is added to the bar as it displaces in the concentric phase. Participants were American football players from a variety of field positions (n=12, height =188 ± 0.01 cm, total body mass = …

Service Dogs: A Scoping Review Of Interdisciplinary Research, K. Lynn Pierce, Nancy A. Dreschel

People and Animals: The International Journal of Research and Practice

Despite a long history of service dogs (SDs) being paired with human partners as a systematic intervention and increasing numbers of and roles for SDs, there remains a lack of empirical knowledge and professional guidance regarding the implementation of SDs into treatment plans for individuals with disabilities. The purpose of this scoping review was to review the peer-reviewed literature specific to SDs and their handlers, to identify successful search term strategies, and to determine in what disciplines research is being conducted. Terminology used in referring to service dogs continues to be a challenge. Through a series of preliminary searches, search …

Grounded School Choice In Uganda: Community Building From The Bottom To The Top, Jennifer Bennett, Joe Bishop, Shima Tondar

Impact: A Journal of Community and Cultural Inquiry in Education

The non-profit organization, From the Bottom to the Top, has been working with the people of west-central Uganda to rebuild the education system, develop increased access to sustainable schools, and promote community involvement in school decisions. This study aimed to explore the perceptions and experiences of students, parents, teachers, and community members related to their choice of specific schools in a rural area of Uganda, which have been working in cooperation with From the Bottom to the Top. Interviews focused on students and families’ motivations to choose the school their children attend and observations of sustainable development efforts in their …

The Effect Submitted Effort Exerted By Cross-Country Players On The Hormone’S Angiotensin 2 And Aldosterone And The Level Of Mineral Salts Responsible For Fluid Balance, Hamza Musa Rababaa, Mohammad Bani Melhem

An-Najah University Journal for Research - B (Humanities)

This study aim was to identify the level of the Angiotensin 2, Aldosterone hormones and some mineral salts (such as Sodium and potassium) among cross country race players before and after the effort. The researcher used the experimental method which is suited with the study nature. The sample contained 6 players of cross-country race team in the Directorate of Education for Al-Koura District, blood samples were drawn from the players before and after the effort that they excerted in the cross-country race players. After processing the data statistically, it was found that the physical exerted effort positively contributed to raising …

Is Nietzscheanism An Extension Of Kant’S Moral Philosophy? A Nietzschean-Kantian Dialectic For Morality, Sami Shaheen

The Undergraduate Research Journal

In contrast to mainstream philosophy, this paper argues that Nietzsche’s philosophy allies itself with Kantian thought despite his explicit resentment towards Kant’s emphasis on metaphysical interpretations of morals. Although Nietzsche’s criticisms towards Kantian philosophy are motivated by his attempts to originally as well as creatively distinguish his thought towards morality from Kant’s metaphysical assertions, it could be argued that Nietzsche’s fear from the advent of nihilism requires a transcendentalist framework to regain value for existentialist concerns. The first section of this paper will argue that Nietzsche’s claims against Kant are nothing more than a broader concealment of Nietzsche’s admiration for …

Microplastics In Water, Their Effects On The Aquatic Ecosystem And Human Public Health, And The Proposed Solutions, Mohanad Abouserie

The Undergraduate Research Journal

We could be swallowing a credit card's weight in plastic every week. Microplastic water pollution is becoming a threat to both humans and aquatic creatures. In this research, microplastic water contamination is discussed, and divergent solutions are proposed. This paper attempts to investigate the causes and effects of such pollution and analyze the current solutions for this issue. The adopted research method is secondary research, where several studies are explored and analyzed. This study explains numerous causes for this issue like cosmetics, cleaning products, factories, and sewage. Consequently, this contamination can negatively impact the organs and metabolisms of the living …