Digital Commons Network^™

Role Of G1p3-Rab5 Interaction In Breast Cancer Gene Expression, Madelyn Terrell

Honors Theses

Breast cancer is one of the most common cancers worldwide with millions of cases diagnosed each year. Despite modern treatments, over 40% of patients can expect to relapse after initial cancer eradication. Consequently, it is crucial to unravel the mechanisms by which breast cells confer their cancerous properties to develop novel treatments that improve patient survival. G1P3 is a mitochondrial localized protein found to be upregulated 50x in estrogen receptorpositive breast cancer and is correlated with overall poor patient survival. G1P3-overexpressing cells display increased amounts of interferon-stimulated genes (ISGs) and G1P3 as an ISG indicates these genes potential to promote …

Academic Evaluation From The Perspective Of Multi-Source Eterogeneous Data:Connotation, Status And Prospect, Sanhong Deng, Jie Yang, Hao Wang, Jia Shen

Journal of Scientific Information Research

[Purpose/significance]Academic evaluation and scientometric methods of synthesizing multisource heterogeneous data have gradually become hot spots in the field. At present， there is no systematic theoretical discussion on academic evaluation from the perspective of multisource heterogeneous data.[Method/process]In view of insufficient utilization of multi-source heterogeneous data， inappropriate research methods， and unclear research objectives， this paper combs the development of academic evaluation from the perspective of multi-source heterogeneous data， and clarifies the connotation and extension of the field， and analyzes the frontiers and hot spots in the field.[Result/conclusion]The results state clearly that from the perspective of multi-source heterogeneous data， academic evaluation manifests the …

Conference Program - Enzyme Engineering Xxvii, Ang Ee Lui, Yan Feng, Li Zhi

Enzyme Engineering XXVII

No abstract provided.

Effects Of Changing Climate Extremes And Vegetation Phenology On Wildlife Associated With Grasslands In The Southwestern United States, Tyler G. Creech, Matthew A. Williamson, Steven E. Sesnie, Esther S. Rubin, Daniel R. Cayan, Erica Fleishman

Human-Environment Systems Research Center Faculty Publications and Presentations

Assessments of the potential responses of animal species to climate change often rely on correlations between long-term average temperature or precipitation and species' occurrence or abundance. Such assessments do not account for the potential predictive capacity of either climate extremes and variability or the indirect effects of climate as mediated by plant phenology. By contrast, we projected responses of wildlife in desert grasslands of the southwestern United States to future climate means, extremes, and variability and changes in the timing and magnitude of primary productivity. We used historical climate data and remotely sensed phenology metrics to develop predictive models of …

One-Way Ticket To Mars: The Privatization Of The Space Industry And Its Environmental Impact On Earth And Beyond, Yuree Nam

Northwestern Journal of Law & Social Policy

In the 21^st century, the space industry has changed from a government-focused practice to a rapidly growing private sector. Billionaires like Elon Musk and Jeff Bezos operate private companies for the advance of space travel and exploration. Other companies like Lunar Outpost, ispace, and Masten Space Systems were selected by NASA to collect lunar resources back in 2020. The concern is that current international space law is insufficient to regulate private actors who play a significant role in exacerbating environmental problems. Whether it be rocket emissions and environmental justice concerns on Earth, or commercial resource extraction in outer space, …

On The Rocks, Below The Rocks: A Study Of Intertidal Life In The Low, Middle And High Zones Of The Puerto Cabuyal – Punta San Clemente Marine Reserve During An El Niño Event, Juliana M. Ferrer

Independent Study Project (ISP) Collection

The rocky intertidal zone is one of the most difficult environments for organisms to survive in due to its harsh biotic and abiotic conditions. As such, it is also one of the best indicators of climate change and an important barrier to beach erosion. This study looked at the rocky intertidal zone of the Puerto Cabuyal-Punta San Clemente Marine Reserve in the Manabí province of Ecuador, with a focus on observing and identifying the organisms found in the area. Data was collected along 30 m transects at varying elevations along the shore using quadrants of two sizes: 50x50 cm for …

Soil Succession: Short And Long-Term Impacts Of Grazing On Soil Properties In A Tropical Montane Cloud Forest, June Curtis

Independent Study Project (ISP) Collection

Cattle ranching is the leading cause of deforestation in South America, causing long-lasting alterations to the continent's landscape and ecology. Tropical montane cloud forests (TMCFs) are a rare ecosystem particularly vulnerable to the effects of land conversion to pasture, a process which has implications ranging from biodiversity loss to soil degradation. Grazing is known to significantly alter soils' physical structure through processes of compaction and erosion as well as significant additions of organic matter. Silvopasture, or the integration of pasture and forest, has emerged as an alternative to traditional grazing practices with the hope of mitigating environmental and soil degradation. …

Community Complexity Of A Pollination Network: Analysis Of Plant-Pollinator Interactions In The Eastern Ecuadorian Cloud Forest, Anisa López-Ruiz

Independent Study Project (ISP) Collection

Global declines in pollinators and temporal/spatial mismatches between plants and pollinators threaten the integrity of plant-pollinator networks. Ecological network analysis provides a powerful framework for understanding the dynamics of plant-pollinator networks and measures of community complexity that can help inform areas of priority in conservation. This study observed a plant-pollinator network in a secondary forest close to the Río Zuñac Reserve in the eastern Ecuadorian cloud forest to identify assemblages of plants and pollinators and evaluate measures of community complexity, including specialization and nestedness. Flowering plants were identified and observed along a 1.2 km transect, and floral visitors to these …

Friends In High Places: Establishing Pollination Networks For The Páramos Of Central Ecuador, Emma Diaz

Independent Study Project (ISP) Collection

Well-known for being a global biodiversity hotspot, the Andean Páramos hosts a unique array of floristic diversity seen nowhere else in the world (Luteyn, n.d.). With the resiliency of this ecosystem dependent on the successful reproduction of these plants, it is crucial to understand the pollination network which sustains them. Modern-day research has outlined networks in the Chilean, Venezuelan, and Argentinean Páramos, but one has yet to be defined for Ecuador, despite being the suspected home to nearly half of floristic diversity in the Páramos (Arroyo et al., 1985; Pelayo et al., 2021; Medan et al., 2023; Caranqui et al., …

Extent Of The 2023 Coral Bleaching Event In The Nargana Region Of Guna Yala, Panama, Brydon Deanna Hollander

Independent Study Project (ISP) Collection

Coral reefs are diverse marine ecosystems that exist in tropical ecosystems all over the world. They provide a myriad of ecological services that are vital for marine organism biodiversity and human coastal communities. A major threat to coral reefs is a rise in sea surface temperature that causes coral bleaching. The effect of a coral bleaching event in Nargana, Guna Yala will be investigated to examine how the health status of coral reef ecosystems are being impacted. To guide these efforts, the extent of coral bleaching will be measured along with whether sea surface temperature (SST), human concentration, and El …

Reef Fish Wariness Behavior: Fish Flight Initiation Distance Mediated By Territoriality And Body Size In Three Reef Sites Off The Western Coast Of Isla Colón, Bocas Del Toro, Panamá, Alina G. Irvine

Independent Study Project (ISP) Collection

Coral reefs are highly productive and diverse underwater ecosystems, providing a variety of environmental services including sand generation, nutrient processing, fish supply, and tourism. However, coral reefs have been increasingly impacted by natural and anthropogenic disturbances, which has negatively affected fish security within their environment. A significant observation is the reduction in evasive behaviors among reef fish in marine reserves compared to those exposed to anthropogenic threats. The present research aims to investigate the factors mediating fish wariness behavior through an exploration of the roles of territoriality and body size on fish flight initiation distance (FID). FID is the distance …

Variation Of Carbon Stock Of Boca Del Drago Mangrove Forests Based On Salinity And Seaward Proximity, Fiona Wyrtzen

Independent Study Project (ISP) Collection

Mangrove forests, at the intersection of land and sea, are considered one of the most important marine environments for their variety of ecosystem services and their ability to sequester large amounts of carbon in their biomass and adjacent soils. With a changing climate, many of the abiotic and biotic factors influencing mangroves will begin to shift, potentially impacting resilience, growth capacity, and distribution of mangroves worldwide. This study aimed to examine the influence of changing salinity on the carbon stock capacity for Rhizophora mangle and Laguncularia racemosa forests, and the distribution of biomass in each species relative to salinity in …

Assessing The Performance Of Agricultural Systems In The Inland And Coastal Regions Of Northern Portugal Using Indicators: Establishing The Foundation Towards Better Agricultural Practices, Genevieve Gehlken

Independent Study Project (ISP) Collection

This study conducts a comprehensive evaluation of agricultural systems in the distinct coastal and inland regions of Northern Portugal. Employing key indicators, including soil erosion, nitrogen surplus, irrigation practices, Agricultural Gross Domestic Product (GDP), and crop yield, the analysis reveals statistically significant disparities and unique challenges in each region. The coastal areas, marked by higher agricultural GDP, exhibit distinct economic dependencies on agriculture, while the inland regions face challenges related to water scarcity, soil erosion, and rural isolation. The looming threat of climate change adds complexity to these dynamics, further highlighting the need for region-specific, sustainable agricultural practices. In the …

Fauna As Fieldworkers: An Analysis On The Use Of Animals As A Form Of Organic Weed And Pest Management In Modern Viticulture, Mariana Del Carmen Campano

Independent Study Project (ISP) Collection

Recent data on the current state of pesticide use in global agriculture suggests serious concerns over significant overuse and negative effects on both environmental and human health, and current trends only suggest continued increases in future global pesticide use. Without prompt, large-scale intervention, this global abuse of chemical pesticides spells significant threats of not only continued harm to global health and environmental quality, but also to the long term viability of agricultural lands and the growing threat of pesticide resistant insects and weeds. Various methods have been explored in the realm of integrated pest management (IPM), but a current lack …

Analyzing Human - Nonhuman Primate Conflict Mitigation Techniques In Mto Wa Mbu, Northern Tanzania, Lily Adams

Independent Study Project (ISP) Collection

Human – non-human primate conflict is particularly crucial due to primates’ high capacity to live among human populations. The study to analyze Human - Nonhuman Primate Conflict Mitigation Techniques, was carried in November 2023 at Mto wa Mbu, Northern Tanzania. To analyze techniques currently being used to mitigate human – non-human primate conflict, this study collected data through semi-structured interviews. Over 87% (n=35) of respondents used multiple mitigation techniques simultaneously. 80% of respondents (n=32) reported using projectiles to ward off foraging primates, 75% of respondents (n=30) reported using loud noises (made either by the voice/body or by manipulating noisemakers), 67.5% …

Representations And Realities: Misali Island's Biodiversity In Hybrid Narratives, Justin Ross Whitney

Independent Study Project (ISP) Collection

Marine Protected Areas (MPAs) are complex organisms that ebb and flow between strict and unyielding conservation doctrines often at the cost of community engagement. Misali Island is different. Conceived and advocated for by community members, this organism has navigated a tumultuous tenure of environmental degradation, periods of high and low funding, and a looming tourism presence. On top of these challenges has been a growing fishing community attempting to share in the bounty of this shockingly biodiverse setting. This study sorts through the grey space of Misali Island by applying a hybrid narrative that interfaces the marine context of the …

The Legacy Of War: A Holistic Analysis Of Socio-Economic And Healthcare Resources For People Affected By Agent Orange In Việt Nam, Ashley Malone

Independent Study Project (ISP) Collection

The war between the United States of America and Northern Việt Nam lasting from 1955 to 1975 did not end with the removal of American troops from Vietnamese soil, but it rears its ugly head daily in the lives of those affected by Agent Orange and other various Rainbow Dioxins utilized as herbicides. This paper delves into the enduring legacy of the Resistance War Against America, specifically focusing on the socio-economic and medical ramifications for families and individuals affected by Agent Orange that persist half a century after its prohibition. The study scrutinizes the disparities in aid between American veterans …

Creating A Framework For An Effective Koala Recovery Center: A Case Study Of Friends Of The Koala, Nsw, Finley Scoular

Independent Study Project (ISP) Collection

Koala populations in New South Wales, Queensland, and the Australian Capital District are currently faced with factors that threaten their survival. Within one decade, their status has shifted from stable to vulnerable to endangered. The cause of this is attributed to increased exposure to dog attacks, vehicle collisions, diseases, and habitat fragmentation and destruction. The koalas' status of endangered in these territories has illuminated the need for human intervention. This study focuses on the specific form of human intervention that involves the rescue, rehabilitation, and release of wild koalas. Due to the recent koala status change from vulnerable to endangered, …

Using Tier 2 Interventions To Close The Achievement Gap In The Middle Grades, Megan Vanderloop

Master's Theses & Capstone Projects

A Multi-Tiered System of Supports (MTSS) in a school district or building creates equitable learning opportunities for all students. Charles City MIddle School (CCMS) has spent the last few years focusing on tier one, which is the universal tier provided to all students. Now that CCMS has implemented strong tier one instruction across the building, their tier two supports for students are an area in need of improvement. The purpose of this school improvement plan is to implement an effective WIN (What I Need) time in seventh and eighth grades at CCMS. Providing interventions outside of the classroom on top …

Communicating Unexpected Genetic Information With Family Members: A Multimethod Study Of Secondary Findings Recipients, Julie Chevalier Sapp

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: Medically-actionable secondary genomic findings (SF) can be life- preserving or life-prolonging for recipients but this benefit can only extend to family members if this information is shared with relatives. How SF recipients communicate this important genetic information with relatives, barriers and facilitators to this process, and SF recipients’ lived experiences in communicating about their results over time remain largely unknown. Family communication is required for relatives of SF recipients to access cascade testing and the potential benefits of enhanced screening and management. Applying behavioral and implementation science theories and providing rich and deep descriptions of SF recipients’ lived experiences …

Trudy Borenstein- Sugiura, Trudy Borenstein- Sugiura

Hacking the Library

No abstract provided.

Soil Adsorption Of Heavy Metals To Protect Groundwater Near Refinery Wastewater Discharge Points, Hamid A. Al-Falahi, Ferdous A. Jabir, Muthanna H. Al-Dahhan

Chemical and Biochemical Engineering Faculty Research & Creative Works

This study presents a strategy to manage the discharge of wastewater, which is either partially treated or untreated, to safeguard the groundwater reserves in the region. a case study involving Ad Diwaniyah refinery wastewater disposal into an adjacent desert was utilized to evaluate the influence of soil adsorption on the attenuation of Pb, Cu, and Cd ion concentrations. Investigation of competitive adsorption of heavy metal ions (Pb2+, Cu2+, and Cd2+) in Dolomite-Limestone soil was conducted through batch and column methods. the adsorption behavior of the bivalent metal cations was observed to be pH dependent. However, the competitive extraction of the …

Need-Oriented Evangelism: Encountering, Embracing, And Experiencing God, Petr Cincala, Allison Sauceda

Faculty Publications

This article provides a fresh perspective on evangelism by reflecting a belief in the Triune God--the source of saving truth and loving community. Mission is part of God’s nature; he is the ultimate Missionary. Mission happens naturally whenever children of God intentionally invite and facilitate God’s presence. Over time, the word “evangelism" has become contaminated by myths, a false understanding of God, and unpleasant religious experiences and practices. Genuine evangelism addresses the most burning issues of people’s lives and should be treated as such. True evangelism involves caring about, praying for, and sharing with people. The practical part of this …

The Osprey, Fall 2023, The Osprey Staff

Osprey

The student magazine of Cal Poly Humboldt.

Socio-Economic Factors And Its Influence On The Association Between Temperature And Dengue Incidence In 61 Provinces Of The Philippines, 2010–2019, Xerxes Seposo, Sary Valenzuela, Geminn Louis Apostol

Ateneo School of Medicine and Public Health Publications

Background

Temperature has a significant impact on dengue incidence, however, changes on the temperature-dengue relationship across axes of socio-economic vulnerability is not well described. This study sought to determine the association between dengue and temperature in multiple locations in the Philippines and explore the effect modification by socio-economic factors.

Method

Nationwide dengue cases per province from 2010 to 2019 and data on temperature were obtained from the Philippines’ Department of Health–Epidemiological Bureau and ERA5-land, respectively. A generalized additive mixed model (GAMM) with a distributed lag non-linear model was utilized to examine the association between temperature and dengue inci-dence. We further …

Caregiver Emotional Support Following Child Sexual Abuse: Links With Child Adjustment Problems, Melissa Sitton

Psychology Theses and Dissertations

Emotional support is theorized to be beneficial to youth after experiences of sexual abuse. However, meta-analytic and systematic reviews of the literature indicate inconsistent evidence of relations between caregiver emotional support and youth functioning after sexual abuse. The current study addressed several methodological factors that may have contributed to inconsistent findings in this literature (i.e., small samples, poor measurement of emotional support, collection of data from only one source) and examined relations between caregiver emotional support and youth functioning after sexual abuse. Participants were 460 youth (M_age = 13.78, SD = 1.77) who presented at a child advocacy …

Assessment And Sourcing Of Heavy Metal Contamination Of Middle East Semi-Enclosed Marine Environs Via Near-Shore Sediment Analysis, Abdullah Alnasser

Civil and Environmental Engineering Theses and Dissertations

Heavy metal contamination in the natural world is complex as many metals can be sourced anthropogenically, naturally, or via both vectors. Many heavy metals are known to be toxic, non-biodegradable, and trophic level bio-magnifiers. Therefore, it is important to monitor and study their concentrations, distributions, and processes for transport and sequestration. Near-shore marine sediments act as a sink for heavy metals in the water column due to their physiochemical properties.

In this dissertation’s second chapter, thirty sediment samples from three latitudinally distinct mangrove areas from the Red Sea of Saudi Arabia (near Yanbu, Jeddah, and the Farasan Islands) were analyzed …

Ua64/2 The Challenge: Magazine For The Center For Gifted Studies (No. 55, Fall 2023), Elizabeth Joyce Editor

Gifted Studies Publications

Magazine created by and about the WKU Center for Gifted Studies.

Zero Textbook Cost Syllabus For Psy 1001 (General Psychology), Phillip Hamid

Open Educational Resources

An introduction to the problems, methods and concepts of psychology, covering a range of topics which characterize the discipline, including history, methodology and professional ethics, biological foundations, perception, motivation and emotion, learning, memory and thinking, individual differences, intelligence, personality, behavior disorders and their treatment, group processes.

Itlos Advisory Opinion On Climate Change: Summary Of Briefs And Statements Submitted To The Tribunal, Maria Antonia Tigre, Korey Silverman-Roati

Sabin Center for Climate Change Law

This report provides a summary of the briefs and statements submitted to the International Tribunal for the Law of the Sea (ITLOS) in response to the Co-Chairs of Commission of Small Island States (COSIS)’ request for an advisory opinion on climate change-related legal questions. The central issue before the ITLOS is whether State Parties to UNCLOS have specific obligations regarding the prevention, reduction, and control of marine environmental pollution stemming from climate change, as well as the protection and preservation of the marine environment concerning climate change impacts. While States and civil society organizations have put forward a variety of …