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2023

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Comparative Economic And Statistical Study About Fish Catch From Manzalah Before And During Dredging Operations For Developing The Lake’S Fisheries, Fattouh Sh, Abd El-Khalek Z., El-Sayed N., Hagag, Sh, Unis R., El- Sonbaty O. Nov 2023

Comparative Economic And Statistical Study About Fish Catch From Manzalah Before And During Dredging Operations For Developing The Lake’S Fisheries, Fattouh Sh, Abd El-Khalek Z., El-Sayed N., Hagag, Sh, Unis R., El- Sonbaty O.

Blue Economy

The bio, social, and economic sustainability of Lake Manzallah fisheries was affected because of pollution, dehydration, and fishers’ / outlaw encroachments. Fish catch and productivity have decreased sharply. The Egyptian government interfered in 2017 and introduced action plan for restoring the lake’s vitality. NIOF research team took part and conducted a research that aims at estimating the secular trend of total fish catch and of the major marine and brackish waters species: Tilapia, Catfish and Mullet, before and during the plan. The research also aims at assessing optimal catch-effort relation before and during the plan, and the effect of the …


Multicellular And Multiscale Models Of Microbes And Host Systems, Elebeoba May Nov 2023

Multicellular And Multiscale Models Of Microbes And Host Systems, Elebeoba May

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Peace Cafe, Ana Cynthia Saenz Jaimes Nov 2023

Peace Cafe, Ana Cynthia Saenz Jaimes

Peace and Conflict Studies Journal Conference

GAMIP Latin America presents Peace Cafe, a participatory and dialogued meeting space, virtual, face-to-face or hybrid, for critical reflection, study, promotion, and practices of Cultures of Peace. We want the exchange and respect of opinions and ideas without polarization.

Peace Cafe is for all GAMIP members and civil society actors, researchers, educational institutions, activists, business people, and governments. We hope to share a good coffee, listen and learning common issues and problems in the region.

This project is organized by GAMIP ALC and is supported for its execution by a registered member, by someone from an organization whose objectives are …


Green Synthesized Silver Nanoparticles-Based Sensing For Monitoring Water Pollution: An Updated Review, Muhamad Allan Serunting, Muhammad Ali Zulfikar, Henry Setiyanto, Dian Ayu Setyorini, Vienna Saraswaty Nov 2023

Green Synthesized Silver Nanoparticles-Based Sensing For Monitoring Water Pollution: An Updated Review, Muhamad Allan Serunting, Muhammad Ali Zulfikar, Henry Setiyanto, Dian Ayu Setyorini, Vienna Saraswaty

Karbala International Journal of Modern Science

Water is a basic human need and has been heavily contaminated. Therefore, it becomes a concern to remove the pollutant and monitor its quality. The removal methods include precipitation, filtration, adsorption, and photodegradation. Meanwhile, the monitoring can be done by measuring and analyzing the contaminant using spectrophotometry and chromatography. Nevertheless, those methods usually need a complicated preparation, and are expensive. Thus, a simple method is necessary to overcome these drawbacks by developing a sensor. In recent years, the sensor performance has been enhanced by using nanomaterials, such as silver nanoparticles (AgNPs). AgNPs can be synthesized using plant extracts through a …


Synthesis And Characterization Of Zirconium Oxide Nanoparticles Using Z. Officinale And S. Aromaticum Plant Extracts For Antibacterial Application, M. J. Tuama, M. F. A. Alias Nov 2023

Synthesis And Characterization Of Zirconium Oxide Nanoparticles Using Z. Officinale And S. Aromaticum Plant Extracts For Antibacterial Application, M. J. Tuama, M. F. A. Alias

Karbala International Journal of Modern Science

Abstract The dramatic rise in bacterial infections and increased resistance to conventional antibiotics has led to the exploration of biologically derived nanomaterials to counteract bacterial activity. Nanotechnology, which deals with materials at the atomic or molecular level, is a promising way to achieve this goal. Zirconium oxide nanoparticles (ZrO2NPs) have shown strong antibacterial effects due to the increased surface-to-volume ratio at the nanoscale. This study focused on the production of ZrO2NPs in an environmentally friendly manner, which included extracts from Zingiber officinale (ginger), where G-ZrO2NPs were produced, and Syzygium aromaticum (clove), which produced S-ZrO2NPs. Various techniques were used, such as …


Predicting A Rationale Weighted Criterion For Admission To Higher Education Institutions, Hala Abubaker Bagabir, Ahmed M. Bagabir Prof. Nov 2023

Predicting A Rationale Weighted Criterion For Admission To Higher Education Institutions, Hala Abubaker Bagabir, Ahmed M. Bagabir Prof.

International Journal for Research in Education

Undergraduate selection, especially for medical degree programs, is a challenging and controversial matter for both national and international institutions. The importance of this paper lies in trying to identify the process of selecting prospective students for medical studies in Saudi Arabia. The currently applied admission criteria are the weighted average score (WAS) of the three pre-university attainments, the general secondary school (GSS), the general aptitude test (GAT), and the scientific achievement test (SAT). There is a different weightage assigned to WAS throughout the national medical institutions. It raises concern about the scientific rationale behind the differences. The present research correlates …


Comparative Analysis Of Swine Antibody Responses Following Vaccination With Live-Attenuated And Killed African Swine Fever Virus Vaccines, Hung Q. Luong, Huong T. L. Lai, Lam Q. Truong, The N. Nguyen, Hanh D. Vu, Hoa T. Nguyen, Lan T. Nguyen, Trang H. Pham, David Scott Mcvey, Hiep Vu Nov 2023

Comparative Analysis Of Swine Antibody Responses Following Vaccination With Live-Attenuated And Killed African Swine Fever Virus Vaccines, Hung Q. Luong, Huong T. L. Lai, Lam Q. Truong, The N. Nguyen, Hanh D. Vu, Hoa T. Nguyen, Lan T. Nguyen, Trang H. Pham, David Scott Mcvey, Hiep Vu

Nebraska Center for Virology: Faculty Publications

African swine fever virus (ASFV) is circulating in many swine-producing countries, causing significant economic losses. It is observed that pigs experimentally vaccinated with a live-attenuated virus (LAV) but not a killed virus (KV) vaccine develop solid homologous protective immunity. The objective of this study was to comparatively analyze antibody profiles between pigs vaccinated with an LAV vaccine and those vaccinated with a KV vaccine to identify potential markers of vaccineinduced protection. Thirty ASFV seronegative pigs were divided into three groups: Group 1 received a single dose of an experimental LAV, Group 2 received two doses of an experimental KV vaccine, …


Starting The Journey To Excellence With A College Faculty Onboarding Program, Robin Cooper, Judith Slapak-Barski Nov 2023

Starting The Journey To Excellence With A College Faculty Onboarding Program, Robin Cooper, Judith Slapak-Barski

HCAS Instructional Design and Pedagogy

The journey to engaged, excellent teaching requires support and preparation for those doing the teaching. In this session, we describe a college Faculty Onboarding Program we developed in 2023 to introduce our new Halmos faculty to NSU (Nova Southeastern University) and to Halmos, and to provide them with the resources and information needed to succeed in their new role—driven by the belief that effective onboarding will lead to higher job satisfaction, better job performance, greater organizational commitment, and reduction in stress. Informed by feedback from recently hired faculty, we identified support strategies to help new faculty thrive by proactively removing …


The Student Movement Volume 108 Issue 7: Not Throwing Away Our Shot: Honoring Hamilton's Legacy, Anneliese Tessalee, Nick Bishop, Grace No, Madison Vath, Amelia Stefanescu, Katrina Johnson, Reagan Mccain, Andrew Francis, Melissa Moore, Brendan Oh, Abby Shim, Reagan Westerman, Robert Zhang, Nicole Compton-Gray, Katie Davis, Anna Rybachek, Rodney Bell Ii, Wambui Karanja Nov 2023

The Student Movement Volume 108 Issue 7: Not Throwing Away Our Shot: Honoring Hamilton's Legacy, Anneliese Tessalee, Nick Bishop, Grace No, Madison Vath, Amelia Stefanescu, Katrina Johnson, Reagan Mccain, Andrew Francis, Melissa Moore, Brendan Oh, Abby Shim, Reagan Westerman, Robert Zhang, Nicole Compton-Gray, Katie Davis, Anna Rybachek, Rodney Bell Ii, Wambui Karanja

The Student Movement v. 108 (2023-2024)

HUMANS

An Arboretum of Beauty, Anneliese Tessalee

Serving with All She's Got: Natalia's Mission Experience in the Dominican Republic, Nick Bishop

WAUS Fall Fundraiser, Grace No

ARTS & ENTERTAINMENT

Art: A Window Into Another Reality, Madison Vath

Filipino Art Through Filipino Eyes: Celebrating A Culture, Amelia Stefanescu

"Free-Falling Into Autumn": A Fall Playlist, Amelia Stefanescu

Upcoming Events in the Art Department, Katrina Johnson

What to do about Inhospitality?: A Review of Mitski's Newest Album, Reagan McCain

NEWS

Andrews Autumn Conference Promotes Peaceful Scientific Discourse, Andrew Francis

Honors Goes to Hamilton, Melissa Moore

Unraveling the Historical Threads: The SDA Church's Journey …


Reduced Grey Matter Volume In Adolescents With Conduct Disorder: A Region‑Of‑Interest Analysis Using Multivariate Generalized Linear Modeling, Ru Zhang, Robert James R. Blair, Karina S. Blair, Matthew Dobbertin, Jaimie Elowsky, Johannah Bashford‑Largo, Ahria J. Dominguez, Melissa Hatch, Sahil Bajaj Nov 2023

Reduced Grey Matter Volume In Adolescents With Conduct Disorder: A Region‑Of‑Interest Analysis Using Multivariate Generalized Linear Modeling, Ru Zhang, Robert James R. Blair, Karina S. Blair, Matthew Dobbertin, Jaimie Elowsky, Johannah Bashford‑Largo, Ahria J. Dominguez, Melissa Hatch, Sahil Bajaj

Center for Brain, Biology, and Behavior: Faculty Publications

Background

Conduct disorder (CD) involves a group of behavioral and emotional problems that usually begins during childhood or adolescence. Structural brain alterations have been observed in CD, including the amygdala, insula, ventrolateral and medial prefrontal cortex, anterior cingulate cortex, and fusiform gyrus. The current study developed a multivariate generalized linear model (GLM) to differentiate adolescents with CD from typically developing (TD) adolescents in terms of grey matter volume (GMV).

Methods

The whole‐brain structural MRI data were collected from 96 adolescents with CD (mean age = 16.188 ± 1.259 years; mean IQ = 104.292 ± 8.107 ; 63 males) and 90 …


A Multi-Organ Maize Metabolic Model Connects Temperature Stress With Energy Production And Reducing Power Generation, Niaz Bahar Chowdhury, Margaret Simons- Senftle, Berengere Decouard, Isabelle Quillere, Martine Rigault, Karuna Anna Sajeevan, Bibek Acharya, Ratul Chowdhury, Bertrand Hirel, Alia Dellagi, Costas Maranas, Rajib Saha Nov 2023

A Multi-Organ Maize Metabolic Model Connects Temperature Stress With Energy Production And Reducing Power Generation, Niaz Bahar Chowdhury, Margaret Simons- Senftle, Berengere Decouard, Isabelle Quillere, Martine Rigault, Karuna Anna Sajeevan, Bibek Acharya, Ratul Chowdhury, Bertrand Hirel, Alia Dellagi, Costas Maranas, Rajib Saha

Department of Chemical and Biomolecular Engineering: Faculty Publications

Climate change has adversely affected maize productivity. Thereby, a holistic understanding of metabolic crosstalk among its organs is important to address this issue. Thus, we reconstructed the first multi-organ maize metabolicmodel, iZMA6517, and contextualized itwith heat and cold stress transcriptomics data using expression distributed reaction flux measurement (EXTREAM) algorithm. Furthermore, implementing metabolic bottleneck analysis on contextualized models revealed differences between these stresses. While both stresses had reducing power bottlenecks, heat stress had additional energy generation bottlenecks.We also performed thermodynamic driving force analysis, revealing thermodynamics-reducing power-energy generation axis dictating the nature of temperature stress responses. Thus, a temperaturetolerant maize ideotype can …


Oregon State Rank Assessment For Klamath Lamprey (Lampetra Similis), Misty Nelson Nov 2023

Oregon State Rank Assessment For Klamath Lamprey (Lampetra Similis), Misty Nelson

Institute for Natural Resources Publications

Oregon state conservation status assessment for Klamath Lamprey (Lampetra similis) using NatureServe methodology, 2023.


November 3, 2023 Ereporter, University Of Alabama At Birmingham Nov 2023

November 3, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Optimal Inverter-Based Resource Installation To Minimize Technical Energy Losses In Distribution Systems, Felipe B. Dantas, Damasio Fernandes, Washington L.A. Neves, Alana K.X.B. Branco, Flavio Costa Nov 2023

Optimal Inverter-Based Resource Installation To Minimize Technical Energy Losses In Distribution Systems, Felipe B. Dantas, Damasio Fernandes, Washington L.A. Neves, Alana K.X.B. Branco, Flavio Costa

Michigan Tech Publications

This paper proposes an algorithm for the optimal installation of inverter-based resources (IBR) composed of wind energy conversion systems, photovoltaic systems, and battery energy storage systems in distribution systems using genetic algorithm (GA) and the cuckoo search (CS) as optimization techniques. The OpenDSS software is used to calculate the power flow in the distribution system with different penetration levels of IBRs. It is used a standard load shape of the IEEE 123 bus system programmed in OpenDSS and irradiance, temperature, and wind speed curves from Brazil. The proposed algorithm, using a genetic algorithm and cuckoo search, was able to define …


Comparative Study Of Photonic Platforms And Devices For On-Chip Sensing, Raghi S. El Shamy, Mohamed A. Swillam, Xun Li Nov 2023

Comparative Study Of Photonic Platforms And Devices For On-Chip Sensing, Raghi S. El Shamy, Mohamed A. Swillam, Xun Li

Faculty Journal Articles

No abstract provided.


2023-11-03 Agenda Book, Morehead State University. Board Of Regents. Nov 2023

2023-11-03 Agenda Book, Morehead State University. Board Of Regents.

Morehead State Board of Regents Agenda Books and Meeting Minutes

Agenda booklet for the Board of Regents meeting of November 3, 2023 which includes the meeting minutes of August 18, 2023.


In Situ Profiling Reveals Metabolic Alterations In The Tumor Microenvironment Of Ovarian Cancer After Chemotherapy, Sara Corvigno, Premal H Thaker, Et Al. Nov 2023

In Situ Profiling Reveals Metabolic Alterations In The Tumor Microenvironment Of Ovarian Cancer After Chemotherapy, Sara Corvigno, Premal H Thaker, Et Al.

2020-Current year OA Pubs

In this study, we investigated the metabolic alterations associated with clinical response to chemotherapy in patients with ovarian cancer. Pre- and post-neoadjuvant chemotherapy (NACT) tissues from patients with high-grade serous ovarian cancer (HGSC) who had poor response (PR) or excellent response (ER) to NACT were examined. Desorption electrospray ionization mass spectrometry (DESI-MS) was performed on sections of HGSC tissues collected according to a rigorous laparoscopic triage algorithm. Quantitative MS-based proteomics and phosphoproteomics were performed on a subgroup of pre-NACT samples. Highly abundant metabolites in the pre-NACT PR tumors were related to pyrimidine metabolism in the epithelial regions and oxygen-dependent proline …


Diagnostic And Commensal Staphylococcus Pseudintermedius Genomes Reveal Niche Adaptation Through Parallel Selection Of Defense Mechanisms, Sanjam S Sawhney, Rhiannon C Vargas, Meghan A Wallace, Carol E Muenks, Brian V Lubbers, Stephanie A Fritz, Carey-Ann D Burnham, Gautam Dantas Nov 2023

Diagnostic And Commensal Staphylococcus Pseudintermedius Genomes Reveal Niche Adaptation Through Parallel Selection Of Defense Mechanisms, Sanjam S Sawhney, Rhiannon C Vargas, Meghan A Wallace, Carol E Muenks, Brian V Lubbers, Stephanie A Fritz, Carey-Ann D Burnham, Gautam Dantas

2020-Current year OA Pubs

Staphylococcus pseudintermedius is historically understood as a prevalent commensal and pathogen of dogs, though modern clinical diagnostics reveal an expanded host-range that includes humans. It remains unclear whether differentiation across S. pseudintermedius populations is driven primarily by niche-type or host-species. We sequenced 501 diagnostic and commensal isolates from a hospital, veterinary diagnostic laboratory, and within households in the American Midwest, and performed a comparative genomics investigation contrasting human diagnostic, animal diagnostic, human colonizing, pet colonizing, and household-surface S. pseudintermedius isolates. Though indistinguishable by core and accessory gene architecture, diagnostic isolates harbor more encoded and phenotypic resistance, whereas colonizing and surface …


Application Of Icp Rie Techniques To Produce Cnt Arrays, Mujtaba Yar Khan Siddiqui Nov 2023

Application Of Icp Rie Techniques To Produce Cnt Arrays, Mujtaba Yar Khan Siddiqui

Theses

Introducing biomolecules into cells is an important process in the field of gene therapy and in developing cures for debilitating illnesses such as HIV and cancer. However, the currently used methods for cellular transfection are slow, inefficient and expensive, causing them to be restrictive. A solution to this problem would be the carbon nanotube (CNT) array devices developed by our research group, which have been shown to be highly efficient at transporting biomolecules into cells. In the current manufacturing process, a sacrificial template with vertically aligned nanopores is used to deposit carbon in, the template then is etched away to …


Identification Of Blood Protein Biomarkers Associated With Prostate Cancer Risk Using Genetic Prediction Models: Analysis Of Over 140,000 Subjects, Hua Zhong, Jingjing Zhu, Shuai Liu, Dalia H Ghoneim, Praveen Surendran, Tao Liu, Sarah Fahle, Adam Butterworth, Md Ashad Alam, Hong-Wen Deng, Herbert Yu, Chong Wu, Lang Wu Nov 2023

Identification Of Blood Protein Biomarkers Associated With Prostate Cancer Risk Using Genetic Prediction Models: Analysis Of Over 140,000 Subjects, Hua Zhong, Jingjing Zhu, Shuai Liu, Dalia H Ghoneim, Praveen Surendran, Tao Liu, Sarah Fahle, Adam Butterworth, Md Ashad Alam, Hong-Wen Deng, Herbert Yu, Chong Wu, Lang Wu

Faculty, Staff and Student Publications

Prostate cancer (PCa) brings huge public health burden in men. A growing number of conventional observational studies report associations of multiple circulating proteins with PCa risk. However, the existing findings may be subject to incoherent biases of conventional epidemiologic studies. To better characterize their associations, herein, we evaluated associations of genetically predicted concentrations of plasma proteins with PCa risk. We developed comprehensive genetic prediction models for protein levels in plasma. After testing 1308 proteins in 79 194 cases and 61 112 controls of European ancestry included in the consortia of BPC3, CAPS, CRUK, PEGASUS, and PRACTICAL, 24 proteins showed significant …


Repurposing Egfr Inhibitors For Oral Cancer Pain And Opioid Tolerance, Maria Daniela Santi, Morgan Zhang, Naijiang Liu, Chi T Viet, Tongxin Xie, Dane D Jensen, Moran Amit, Huilin Pan, Yi Ye Nov 2023

Repurposing Egfr Inhibitors For Oral Cancer Pain And Opioid Tolerance, Maria Daniela Santi, Morgan Zhang, Naijiang Liu, Chi T Viet, Tongxin Xie, Dane D Jensen, Moran Amit, Huilin Pan, Yi Ye

Faculty, Staff and Student Publications

Oral cancer pain remains a significant public health concern. Despite the development of improved treatments, pain continues to be a debilitating clinical feature of the disease, leading to reduced oral mobility and diminished quality of life. Opioids are the gold standard treatment for moderate-to-severe oral cancer pain; however, chronic opioid administration leads to hyperalgesia, tolerance, and dependence. The aim of this review is to present accumulating evidence that epidermal growth factor receptor (EGFR) signaling, often dysregulated in cancer, is also an emerging signaling pathway critically involved in pain and opioid tolerance. We presented preclinical and clinical data to demonstrate how …


Identification Of Circulating Proteins Associated With General Cognitive Function Among Middle-Aged And Older Adults, Adrienne Tin, Alison E Fohner, Qiong Yang, Jennifer A Brody, Gail Davies, Jie Yao, Dan Liu, Ilana Caro, Joni V Lindbohm, Michael R Duggan, Osorio Meirelles, Sarah E Harris, Valborg Gudmundsdottir, Adele M Taylor, Albert Henry, Alexa S Beiser, Ali Shojaie, Annabell Coors, Annette L Fitzpatrick, Claudia Langenberg, Claudia L Satizabal, Colleen M Sitlani, Eleanor Wheeler, Elliot M Tucker-Drob, Jan Bressler, Josef Coresh, Joshua C Bis, Julián Candia, Lori L Jennings, Maik Pietzner, Mark Lathrop, Oscar L Lopez, Paul Redmond, Robert E Gerszten, Stephen S Rich, Susan R Heckbert, Thomas R Austin, Timothy M Hughes, Toshiko Tanaka, Valur Emilsson, Ramachandran S Vasan, Xiuqing Guo, Yineng Zhu, Christophe Tzourio, Jerome I Rotter, Keenan A Walker, Luigi Ferrucci, Mika Kivimäki, Monique M B Breteler, Simon R Cox, Stephanie Debette, Thomas H Mosley, Vilmundur G Gudnason, Lenore J Launer, Bruce M Psaty, Sudha Seshadri, Myriam Fornage Nov 2023

Identification Of Circulating Proteins Associated With General Cognitive Function Among Middle-Aged And Older Adults, Adrienne Tin, Alison E Fohner, Qiong Yang, Jennifer A Brody, Gail Davies, Jie Yao, Dan Liu, Ilana Caro, Joni V Lindbohm, Michael R Duggan, Osorio Meirelles, Sarah E Harris, Valborg Gudmundsdottir, Adele M Taylor, Albert Henry, Alexa S Beiser, Ali Shojaie, Annabell Coors, Annette L Fitzpatrick, Claudia Langenberg, Claudia L Satizabal, Colleen M Sitlani, Eleanor Wheeler, Elliot M Tucker-Drob, Jan Bressler, Josef Coresh, Joshua C Bis, Julián Candia, Lori L Jennings, Maik Pietzner, Mark Lathrop, Oscar L Lopez, Paul Redmond, Robert E Gerszten, Stephen S Rich, Susan R Heckbert, Thomas R Austin, Timothy M Hughes, Toshiko Tanaka, Valur Emilsson, Ramachandran S Vasan, Xiuqing Guo, Yineng Zhu, Christophe Tzourio, Jerome I Rotter, Keenan A Walker, Luigi Ferrucci, Mika Kivimäki, Monique M B Breteler, Simon R Cox, Stephanie Debette, Thomas H Mosley, Vilmundur G Gudnason, Lenore J Launer, Bruce M Psaty, Sudha Seshadri, Myriam Fornage

Faculty, Staff and Student Publications

Identifying circulating proteins associated with cognitive function may point to biomarkers and molecular process of cognitive impairment. Few studies have investigated the association between circulating proteins and cognitive function. We identify 246 protein measures quantified by the SomaScan assay as associated with cognitive function (p < 4.9E-5, n up to 7289). Of these, 45 were replicated using SomaScan data, and three were replicated using Olink data at Bonferroni-corrected significance. Enrichment analysis linked the proteins associated with general cognitive function to cell signaling pathways and synapse architecture. Mendelian randomization analysis implicated higher levels of NECTIN2, a protein mediating viral entry into neuronal cells, with higher Alzheimer's disease (AD) risk (p = 2.5E-26). Levels of 14 other protein measures were implicated as consequences of AD susceptibility (p < 2.0E-4). Proteins implicated as causes or consequences of AD susceptibility may provide new insight into the potential relationship between immunity and AD susceptibility as well as potential therapeutic targets.


A Multicenter Study Validates The Who 2022 Classification For Conjunctival Melanocytic Intraepithelial Lesions With Clinical And Prognostic Relevance, Hardeep Singh Mudhar, Yamini Krishna, Simon Cross, Claudia Auw-Haedrich, Raymond Barnhill, Svetlana Cherepanoff, Ralph Eagle, James Farmer, Robert Folberg, Hans Grossniklaus, Martina C. Herwig-Carl, Martin Hyrcza, Sandra Lassalle, Karin U. Loeffler, Alexandre Moulin, Tatyana Milman, Robert M. Verdijk, Steffen Heegaard, Sarah E. Coupland Nov 2023

A Multicenter Study Validates The Who 2022 Classification For Conjunctival Melanocytic Intraepithelial Lesions With Clinical And Prognostic Relevance, Hardeep Singh Mudhar, Yamini Krishna, Simon Cross, Claudia Auw-Haedrich, Raymond Barnhill, Svetlana Cherepanoff, Ralph Eagle, James Farmer, Robert Folberg, Hans Grossniklaus, Martina C. Herwig-Carl, Martin Hyrcza, Sandra Lassalle, Karin U. Loeffler, Alexandre Moulin, Tatyana Milman, Robert M. Verdijk, Steffen Heegaard, Sarah E. Coupland

Wills Eye Hospital Papers

Several nomenclature and grading systems have been proposed for conjunctival melanocytic intraepithelial lesions (C-MIL). The fourth "WHO Classification of Eye Tumors" (WHO-EYE04) proposed a C-MIL classification, capturing the progression of noninvasive neoplastic melanocytes from low- to high-grade lesions, onto melanoma in situ (MIS), and then to invasive melanoma. This proposal was revised to the WHO-EYE05 C-MIL system, which simplified the high-grade C-MIL, whereby MIS was subsumed into high-grade C-MIL. Our aim was to validate the WHO-EYE05 C-MIL system using digitized images of C-MIL, stained with hematoxylin and eosin and immunohistochemistry. However, C-MIL cases were retrieved from 3 supraregional ocular pathology …


Glutamate Receptor Dysregulation And Platelet Glutamate Dynamics In Alzheimer's And Parkinson's Diseases: Insights Into Current Medications, Deepa Gautam, Ulhas Naik, Meghna Naik, Santosh Yadav, Rameshwar Nath Chaurasia, Debabrata Dash Nov 2023

Glutamate Receptor Dysregulation And Platelet Glutamate Dynamics In Alzheimer's And Parkinson's Diseases: Insights Into Current Medications, Deepa Gautam, Ulhas Naik, Meghna Naik, Santosh Yadav, Rameshwar Nath Chaurasia, Debabrata Dash

Cardeza Foundation for Hematologic Research

Two of the most prevalent neurodegenerative disorders (NDDs), Alzheimer's disease (AD) and Parkinson's disease (PD), present significant challenges to healthcare systems worldwide. While the etiologies of AD and PD differ, both diseases share commonalities in synaptic dysfunction, thereby focusing attention on the role of neurotransmitters. The possible functions that platelets may play in neurodegenerative illnesses including PD and AD are becoming more acknowledged. In AD, platelets have been investigated for their ability to generate amyloid-ß (Aß) peptides, contributing to the formation of neurotoxic plaques. Moreover, platelets are considered biomarkers for early AD diagnosis. In PD, platelets have been studied for …


The What And How Of Essential Thematic Analysis, Elih Sutisna Yanto Nov 2023

The What And How Of Essential Thematic Analysis, Elih Sutisna Yanto

The Qualitative Report

Gareth Terry and Nikki Hayfield's book, Essentials of Thematic Analysis, introduces readers to reflexive thematic analysis, a method for analyzing interview and focus group transcripts, qualitative survey responses, and other qualitative data. This method is based on the understanding that we all exist in a context from which we can see and speak. In this way, researchers produce knowledge that represents situated truths and allow them to understand others’ perspectives on a given topic. The book shows how to construct a “positioned reality of the situation” from qualitative data. According to the authors, this method is not a methodology …


Ties That Blind: A Longitudinal Study On Consanguinity And Congenital Disorders In Kabirwala, Pakistan, Hifza Irfan, Abida Sharif, Imran Sabir, Saeed Ahmad Watto, Muhammad Zaman Nov 2023

Ties That Blind: A Longitudinal Study On Consanguinity And Congenital Disorders In Kabirwala, Pakistan, Hifza Irfan, Abida Sharif, Imran Sabir, Saeed Ahmad Watto, Muhammad Zaman

The Qualitative Report

Consanguineous marriage, defined as marriage between close relatives, is a prevalent practice in many traditional societies. It is commonly perceived to secure property rights, maintain social cohesion, and fortify kinship structures. However, consanguineous marriages are also associated with an increased risk of inbreeding and consequent chromosomal disorders. Pakistan has one of the highest rates of consanguineous marriage worldwide, with an estimated 60% of all marriages occurring between close relatives. This study focuses on the persistence of consanguinity in Kabirwala, Pakistan, a town in the Punjab province. It investigates the trend of consanguinity and relative affinity according to generations in Kabirwala. …


Integrated Periphyton Biofilters In Marine Recirculating Aquaculture Systems, Adam N. Bell Nov 2023

Integrated Periphyton Biofilters In Marine Recirculating Aquaculture Systems, Adam N. Bell

USF Tampa Graduate Theses and Dissertations

Marine aquaculture is a growing industry that has the potential to reduce eutrophication, overfishing, and loss of biodiversity. Recirculating aquaculture systems (RAS) are a type of aquaculture system that decreases discharge, raises biological control, and conserves water; however, RAS are challenged due to high energy cost, low biodiversity, water quality control, and waste nutrients. Periphyton biofilters are a new technology that allows for feed production, water quality control, microbial diversity, and resource recovery in marine aquaculture systems. The overarching question that this dissertation investigates is, how can periphyton biofilters be integrated into RAS to address the challenges of modern sustainable …


Brain Metastasis-Associated Fibroblasts Secrete Fucosylated Pvr/Cd155 That Induces Breast Cancer Invasion, Emma Adhikari Nov 2023

Brain Metastasis-Associated Fibroblasts Secrete Fucosylated Pvr/Cd155 That Induces Breast Cancer Invasion, Emma Adhikari

USF Tampa Graduate Theses and Dissertations

Breast cancer (BC) continues to be the most diagnosed cancer and the second leading cause of cancer deaths in women worldwide. High mortality, in most cancers, is due to metastasis; BC is the most common source of one of the deadliest forms of metastasis–brain metastasis (BM) in female. Patients with triple negative breast cancer (TNBC) exhibit the highest incidence of BM and poorest survival outcomes upon diagnosis with BM. The prognosis of breast cancer brain metastasis (BCBM) remains poor because the blood–brain barrier (BBB) prevents the uptake of drug substances, including chemotherapeutic agents, targeted agents, and toxins, from the brain. …


Procedures For Assessment Of The Marine Carbon System And Evaluation Of Access And Ocean Acidification Literacy In The Deaf Community, Loraine Martell-Bonet Nov 2023

Procedures For Assessment Of The Marine Carbon System And Evaluation Of Access And Ocean Acidification Literacy In The Deaf Community, Loraine Martell-Bonet

USF Tampa Graduate Theses and Dissertations

One major goal of this dissertation addresses the need for improved laboratory procedures to measure chemical changes in seawater caused by the uptake of atmospheric CO2, especially in coastal environments. Due to the proximity of anthropogenic stressors in the coastal zone, the biogeochemical complexity of the CO2 system is more dynamic than the open ocean. My principal research objectives were addressed by developing methods for (1) improving the accuracy of pH measurements over a wide range of salinities and (2) investigating the acid-base properties of natural organics in the coastal ocean.

The accuracy of pH electrode calibrations is affected when …


Oregon State Rank Assessment For Umpqua Dace (Rhinichthys Evermanni), Misty Nelson Nov 2023

Oregon State Rank Assessment For Umpqua Dace (Rhinichthys Evermanni), Misty Nelson

Institute for Natural Resources Publications

Oregon state conservation status assessment for Umatilla dace (Rhinichthys evermanni) using NatureServe methodology, 2023.