Digital Commons Network^™

Draft Final 2023 Residential Metals Abatement Program (Rmap) Whitehall Borrow Submittal, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Mutation Of Key Signaling Regulators Of Cerebrovascular Development In Vein Of Galen Malformations, Shujuan Zhao, Po-Ying Fu, Yung-Chun Wang, Sheng Chih Jin, Et Al.

2020-Current year OA Pubs

To elucidate the pathogenesis of vein of Galen malformations (VOGMs), the most common and most severe of congenital brain arteriovenous malformations, we performed an integrated analysis of 310 VOGM proband-family exomes and 336,326 human cerebrovasculature single-cell transcriptomes. We found the Ras suppressor p120 RasGAP (RASA1) harbored a genome-wide significant burden of loss-of-function de novo variants (2042.5-fold, p = 4.79 x 10

In Yellow: A Solo Poem-Play, Emily Kitchens

Faculty Articles

“In Yellow” was developed in the INKubator residency at Art House Productions (Jersey City, NJ) in 2019 with the following blurb:

In Yellow is a solo poem-play about a relationship between a young woman and a ceramic doll her grandmother made that she has just accidentally broken. It is about grief. It is about breaking out of generationally instilled feminine values. It is about the color yellow. It’s all true.

“In Yellow” is an experiment of a poem and play for one voice. I was in New York City for about 10 years, before that The Bay Area, but am …

Nlm Scrubber To De-Identify Clinical Text Data And Facilitate Data Sharing, Christine Nieman Hislop, Katie Pierce-Farrier

Medical Institutional Repositories in Libraries (MIRL)

Before sharing clinical data, personal and sensitive information must be removed or de-identified. The NLM Scrubber is a clinical text de-identification tool developed by the National Library of Medicine. This session will give a brief introduction to different branches of AI. Natural language processing (NLP) is one such branch of AI that combines linguistics and computer science to make human language understandable to computers. The NLM Scrubber uses NLP to identify personally identifying information and replace it with generic terms. It is a freely available tool that can be customized to look for and redact specific terms and phrases. NLM …

Modifying Koha To Use As A Local Authors' Catalog, Fred King

Medical Institutional Repositories in Libraries (MIRL)

Koha is a widely-used Integrated Library System, free to download, free to use. It is open-source software, is infinitely configurable and can be used in a variety of ways. This presentation will show how MedStar Washington Hospital Center is using Koha and modified Medline records to track articles written by MedStar authors.

Bmi Superior To Fat-Free Mass Index And Fat Mass Index For Predicting Arterial Stiffness In College Students, Amanda Callaghan, Kennedy Kerbs, Kyndal Downing, Zachary Zeigler

International Journal of Exercise Science: Conference Proceedings

Arterial stiffness is a significant predictor of cardiovascular disease and mortality. Body mass index (BMI) has been used to predict cardiovascular disease outcomes but does not consider fat and lean mass. Fat mass index (FMI) and fat-free mass index (FFMI) may be superior to BMI in predicting arterial stiffness because it considers body composition. PURPOSE: This study aims to determine if FFMI and FMI are superior to BMI at predicting arterial stiffness in college students. METHODS: Participants came into the exercise physiology lab, signed consent, and then had anthropometric measurements of height and weight taken, as well as …

Decriminalization Of Suicide In India, Kallabi Borah, Tessy Treesa Jose, Anil Kumar M Nagaraj

Manipal Journal of Nursing and Health Sciences

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Medical School Watercooler Newsletter - November 16, 2023, Lindsey Lyle

Watercooler Newsletter

This is the November 16, 2023 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Students and faculty share unique patient cases at national OB-GYN conference
• Sign up for spring 2024 cohort of Academic Medicine Coach Training Program
• Pathology resident presents at leading pathology conferences

Moving Beyond The 2018 Minimum International Care Considerations For Osteoporosis Management In Duchenne Muscular Dystrophy (Dmd): Meeting Report From The 3rd International Muscle-Bone Interactions Meeting 7th And 14th November 2022, Kim Phung, Nicola Crabtree, Anne M. Connolly, Pat Furlong, Eric P. Hoffman, Stefan A. Jackowski, Soher Nagi Jayash, Alex Johnson, Khaldoun Koujok, Craig F. Munns, Erik Niks, Frank Rauch, Rachel Schrader, Cathy Turner, Elizabeth Vroom, David R. Weber, Brenda L. Wong, Michela Guglieri, Leanne M. Ward, Sze Choong Wong

Pharmacy Faculty Scholarship

This current manuscript summarizes the proceedings of the “Third Muscle-bone interactions in Duchenne Muscular Dystrophy Symposium: Moving Beyond the 2018 Minimum International Standards of Care for Osteoporosis Management”, an event co-organized by the World Duchenne Organization (www.worldduchenne.org) and the International Conference on Children’s Bone Health (www.theiscbh.org). This virtual symposium, held on November 7th and 14th 2022, brought together a total of 385 delegates representing 55 countries registered for the symposium, which included 239 clinicians, 70 researchers, 40 patient representatives and others from pharmaceutical companies and regulators. This symposium aimed to review the evidence base that informed the 2018 international minimum …

Issue 431: November 16-30, 2023, The Local Voice

The Local Voice

No abstract provided.

The View From Ventress - 2022-23 Academic Year, University Of Mississippi, College Of Liberal Arts

Liberal Arts Newsletters

News from the College of Liberal Arts

Provoking Gut-Level Reactions: A Study On Journalistic Framing During The 2020 Meatpacking Crisis, Michelle Rossi, Patrick Ferrucci

Journalism and Communication Faculty Publications

This study investigates news frames used by mainstream news media in the United States to portray the 2020 meatpacking crisis. By integrating framing and animal standpoint theory, it reveals the mechanisms that perpetuate social ignorance about daily practices within the meat industry, particularly those that exclude the perspectives of farmed animals. Through an engagement with intersectional ecofeminism and Critical Animal and Media Studies (CAMS), the investigation probes the cyclical patterns of violence inflicted upon farmed animals in the meat industry as portrayed by news outlets, a phenomenon that simultaneously impacts marginalized human communities. The inclusion of farmed animals as news …

Social Capital Associates With Better Cognitive Health, Oral Health And Epigenetic Age Deceleration: Findings From The Canadian Longitudinal Study On Aging., Aileen Liang, Noha Gomaa

Department of Medicine Publications

Background: Social exposures are linked to an array of health outcomes, especially around aging. In this study, we examined the association of social capital, defined as social relationships and networks, with clinical and biological outcomes including cognitive health, oral inflammation, and epigenetic aging. Methods: We used data from the Canadian Longitudinal Study on Aging (CLSA) (n =1,479; aged 45–85 years), categorizing social capital as structural and cognitive capital. Oral inflammation was determined as the presence of gum bleeding. Epigenetic aging was computed as the difference between chronological age and DNA methylation age. We constructed multivariable regression models adjusted for covariates …

Testosterone Is Positively Associated With Coronary Artery Calcium In A Low Cardiovascular Disease Risk Population, Benjamin Trumble, Jacob Negrey, Stephanie V. Koebele, Randall C. Thompson, L. Samuel Wann, Adel H. Allam, Bret Beheim, M. Linda Sutherland, James D. Sutherland, Daniel Eid Rodriguez, David E. Michalik, Chris J. Rowan, Guido P. Lombardi, Angela R. Garcia, Daniel K. Cummings, Edmond Seabright, Sarah Alami, Thomas S. Kraft, Paul L. Hooper, Kenneth Buetow, Andrei Irimia, Margaret Gatz, Jonathan Stieglitz, Michael D. Gurven, Hillard Kaplan, Gregory S. Thomas, Tsimane Health And Life History Project Teams

ESI Publications

Background

In industrialized populations, low male testosterone is associated with higher rates of cardiovascular mortality. However, coronary risk factors like obesity impact both testosterone and cardiovascular outcomes. Here, we assess the role of endogenous testosterone on coronary artery calcium in an active subsistence population with relatively low testosterone levels, low cardiovascular risk and low coronary artery calcium scores.

Methodology

In this cross-sectional community-based study, 719 Tsimane forager-horticulturalists in the Bolivian Amazon aged 40+ years underwent computed tomography (49.8% male, mean age 57.6 years).

Results

Coronary artery calcium levels were low; 84.5% had no coronary artery calcium. Zero-inflated negative binomial models …

Spectator 2023-11-16, Editors Of The Spectator

The Spectator

No abstract provided.

The Current - Volume 34 Issue 6, Nova Southeastern University

Student Newspapers

No abstract provided.

Effects Of Doxorubicin On Extracellular Matrix Regulation In Primary Cardiac Fibroblasts From Mice, Cameron Skaggs, Steve Nick, Conner Patricelli, Laura Bond, Kali Woods, Luke Woodbury, Julia Thom Oxford, Xinzhu Pu

Biomedical Research Institute Publications and Presentations

Objective Doxorubicin (DOX) is a highly effective chemotherapeutic used to treat many adult and pediatric cancers. However, its use is limited due to a dose-dependent cardiotoxicity, which can lead to lethal cardiomyopathy. In contrast to the extensive research efforts on toxic effects of DOX in cardiomyocytes, its effects and mechanisms on cardiac extracellular matrix (ECM) homeostasis and remodeling are poorly understood. In this study, we examined the potential effects of DOX on cardiac ECM to further our mechanistic understanding of DOX-induced cardiotoxicity.

Results DOX-induced significant down-regulation of several ECM related genes in primary cardiac fibroblasts, including Adamts1, Adamts5, Col4a1, Col4a2, …

Special November 2023 Faculty Senate Meeting, University Of Nebraska At Kearney Faculty Senate

Faculty Senate Packets

No abstract provided.

The Montclarion, November 16, 2023, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Conquer And Prevail Issue 151 November 16 2023, Wofford College. Office Of Marketing And Communications

Conquer and Prevail Newsletter

No abstract provided.

Curriculum Minutes 11/16/2023, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.

Association Of Adverse Childhood Experiences And Behavioral Health Among Children And Adolescents In The United States, Sanjaya Regmi

Electronic Theses and Dissertations Archive

Adverse childhood experiences (ACEs) have enduring implications for various behavioral and mental health issues, necessitating a thorough examination of factors that mitigate their adverse effects. The present research draws upon the Healthy Outcomes from Positive Experiences (HOPE) framework and the socioecological model to investigate the moderating role of different types of resilience, including child resilience, family resilience, safe neighborhoods, and supportive neighborhoods, on the associations between ACEs, substance use disorder (SUD), and depression. This study also explores the relationships between ACEs and mental health care needs and service utilization among children and adolescents in the United States. We conducted cross-sectional …

Engaging Students In A Genetics Course-Based Undergraduate Research Experience Utilizing Caenorhabditis Elegans In Hybrid Learning To Explore Human Disease Gene Variants, Natalie Forte, Virginia Veasey, Bethany Christie, Amira Carter, Marli Hanks, Alan Holderfield, Taylor Houston, Anil Challa, Ashley Turner

Research, Publications & Creative Work

Genetic analysis in model systems using bioinformatic approaches provides a rich context for a concrete and conceptual understanding of gene structure and function. With the intent to engage students in research and explore disease biology utilizing the nematode Caenorhabditis elegans model, we developed a semester-long course-based undergraduate research experience (CURE) in a hybrid (online/in-person) learning environment—the gene-editing and evolutionary nematode exploration CURE (GENE-CURE). Using a combination of bioinformatic and molecular genetic tools, students performed structure-function analysis of disease-associated variants of uncertain significance (VUS) in human orthologs. With the aid of a series of workshop-style research sessions, students worked in teams …

Quantifying Non-Gaussian Intermittent Fluctuations In Physiology: Multiscale Probability Density Function Analysis Using The Savitzky-Golay Detrending, Madhur Mangalam, Damian G. Kelty-Stephen, Eiichi Watanabe, Ken Kiyono

Journal Articles

When measuring physiological data, the central limit theorem typically implies a consistent variance, resulting in data that closely follow a Gaussian distribution. However, physiological measurements often deviate from this expectation, increasing variance due to nonlinear correlations across various scales. The challenge lies in testing these tails, which comprise only rare and extreme values. We introduce multiscale probability density function (PDF) analysis, a method that estimates this non-Gaussianity parameter for physiological fluctuations in each of multiple timescales. We gain valuable insights into the observed distributions with heavier tails and nonlinear correlations by exploring the relationship between non-Gaussianity and logarithmic scale. To …

Oregon State Rank Assessment For Blue Mountainsnail (Oreohelix Strigosa Delicata), Misty Nelson

Institute for Natural Resources Publications

Oregon state conservation status assessment for Blue mountainsnail (Oreohelix strigosa delicata) using NatureServe methodology, 2023.

Improving Cellphone-Based Bio-Imaging Technique For Fluorescence Detection, Erteza T. Efaz

LSU Master's Theses

The research presented in this thesis focuses on the design, development, and evaluation of a fluorescence detection system. The system is implemented primarily as an Android application, Auto Camera, which leverages smartphone cameras to capture and analyze fluorescent images. The application provides a user-friendly interface with some configurable features like exposure time, ISO speed, and storage limit; as well as defining detection thresholds and setting acquisition intervals. This study begins with the architectural framework of the Android application, which is written in Java using Android Studio. The API compatibility is set to version 33, and users are prompted to grant …

Loss Of Cftr Function In Macrophages Alters The Cell Transcriptional Program And Delays Lung Resolution Of Inflammation, Dianne Wellems, Yawen Hu, Scott Jennings, Guoshun Wang

School of Graduate Studies Faculty Publications

Cystic fibrosis (CF) is an autosomal recessive genetic disorder caused by mutations in the CF Transmembrane-conductance Regulator (CFTR) gene. The most severe pathologies of CF occur in the lung, manifesting as chronic bacterial infection, persistent neutrophilic inflammation, and mucopurulent airway obstruction. Despite increasing knowledge of the CF primary defect and the resulting clinical sequelae, the relationship between the CFTR loss of function and the neutrophilic inflammation remains incompletely understood. Here, we report that loss of CFTR function in macrophages causes extended lung inflammation. After intratracheal inoculation with Pseudomonas aeruginosa, mice with a macrophage-specific Cftr-knockout (Mac-CF) were able to mount an …

Multi-Model Digital Twins With Ai Forecasting For Seed To Stand Supply Chain, Rania Sherif Elashmawy

USF Tampa Graduate Theses and Dissertations

The present dissertation embodies a multi-faceted investigation aimed at enhancing strawberry production pre-harvest and post-harvest quality through data-driven approaches. It unfolds multi-stages framework.

The first stage presents a complete data collection and its preliminary statistical analysis obtained from the first phase of a large-scale soil study on how to improve strawberry production and achieve sustainable and high-quality harvests through sensor-assisted real-time field monitoring. Six real-time loggers were placed in an operational commercial strawberry farm in Central Florida for the entirety of a harvest season from soil preparation to planting to harvesting. Along with high-resolution soil sensory measurements including water content, …

Association Between Trigeminal Neuralgia And Degenerative Cervical Myelopathy: A Cross‐Sectional Study Using Us Data, Robert J. Trager

Faculty Scholarship

Background: Limited research has suggested that trigeminal neuralgia (TN), an often-idiopathic pain disorder affecting the face and head, may arise from compression of the cervical spinal cord due to involvement of the spinal trigeminal tract. We hypothesized that adults with TN would have a greater likelihood of concurrent degenerative cervical myelopathy (DCM) compared to matched adults without TN. Methods: We retrieved de-identified data from a US network (TriNetX, Inc.) including medical records of >113 million patients, with a query date of October 1, 2023, and data spanning the previous 20 years. We created two groups of adults (aged ≥18 years): …

Understanding The Implications Of Underreporting, Vaccine Efficiency And Social Behavior On The Post-Pandemic Spread Using Physics Informed Neural Networks: A Case Study Of China, Samiran Ghosh, Alonso Ogueda-Oliva, Aditi Ghosh, Malay Banerjee

Faculty Publications

In late 2019, the emergence of COVID-19 in Wuhan, China, led to the implementation of stringent measures forming the zero-COVID policy aimed at eliminating transmission. Zero COVID policy basically aimed at completely eliminating the transmission of COVID-19. However, the relaxation of this policy in late 2022 reportedly resulted in a rapid surge of COVID-19 cases. The aim of this work is to investigate the factors contributing to this outbreak using a new SEIR-type epidemic model with time-dependent level of immunity. Our model incorporates a time-dependent level of immunity considering vaccine doses administered and time-post-vaccination dependent vaccine efficacy. We find that …