Digital Commons Network^™

Unusual Chromosome Configurations: Evaluation Of Sex Univalent And Trivalent Chromosome Models, Ashley B. Borseth

Master’s Theses

Aneuploidy, or abnormal number of chromosomes in a haploid set, in XY/XX organisms has consequences that can impede physical and cognitive development. To prevent aneuploidy, cellular division relies on the correct position of paired chromosomes and subsequent segregation in the meiotic program. If connections between paired chromosomes sever or errors in chromosome contraction towards spindle poles arise, aneuploidy occurs. Many arthropod species have chromosomes that naturally do not pair, or that pair differently than typical autosomes. Through the evaluation of such systems, novel insights into chromosomal coordination and positioning may be revealed. The objective of this study is twofold: (1) …

Relationships Between Behavior, Energy Metabolites, And Corticosterone In Black-Legged Kittiwake (Rissa Tridactyla) Nestlings, Sierra Pete

Master’s Theses

Birds can cope with energy-shifting challenges by redirecting energy and behavior to maintain energetic homeostasis. Nestlings allocate energy to support their rapid growth and developmental period; thus, their challenges and the subsequent energetic demands can be much different than an adult. At a baseline level, energy is constantly shifting in response to regularly occurring challenges; however, more substantial challenges can initiate the production of glucocorticoid hormones. In birds, the main glucocorticoid is corticosterone. Corticosterone is believed to aid in energy homeostasis by redirecting energy metabolite mobilization. Energy metabolites are intermediaries or end products of cellular metabolism, thus, metabolites like glucose …

Temperature-Dependent Diffusion In Block Copolymer Organogels, Ridwana Bashar

Master’s Theses

Organogels are often considered for transport-based applications such as transdermal drug delivery vehicles and gel actuators due to their unique properties. Recent consideration of styrenic block copolymer based organogels’ application in transdermal drug delivery requires an extensive investigation of drug diffusion behavior through these gels to assess their applicability. Temperature is a major influencing parameter on diffusion. The goal of this research is to better understand the impact of temperature on diffusion in styrenic triblock copolymer organogels. To accomplish this goal, we focused on three specific objectives: (i) accurately measure the diffusivities of a solute – AOT reverse micelles – …

Genetic Substrates Of The Initial Subjective Rewarding Effects Of Alcohol In Mice, Holly Jones

Master’s Theses

Susceptibility to alcohol use disorders (AUDs) arises from a complex interplay of genetics and environmental experiences. While the initial subjective response predicts susceptibility to AUD, genetic variation is responsible for about 50% of an individual's risk. This study used a single-exposure conditioned place preference paradigm (SE-CPP) to identify phenotypic and genetic correlates of the initial subjective rewarding effects of alcohol (EtOH) in diversity outbred (DO) mice. We assessed the relationship between SE-CPP and anxiety-like behaviors using a marble burying test and light-dark box test. Ninety-six male and female diversity outbred mice were tested in a Marble Burying test at 7-8 …

Bibliography, Aaron W. Hughey

Faculty/Staff Personal Papers

Bibliography of publications by Aaron W. Hughey.

Bibliography, Bruce Kessler

Faculty/Staff Personal Papers

Bibliography of publications by Bruce Kessler.

Enhancing Resilience In Classrooms, Elizabeth Doll, Samuel Y. Song

Department of Educational Psychology: Faculty Publications

Schools have historically been the great equalizer in American communities—the “ticket out” for youth struggling to overcome adversity and pov­erty (Pianta & Walsh, 1998). For children who immigrated to the United States at the turn of the twentieth century schools were safe havens where they learned English received public health services and became literate and employable (Fagan, 2000; Goldstein, 2014). As each wave of homesteaders moved west across the country schools popped up alongside the newly broken sod. Universal access to public education is a defining feature of the North American society and schools are fertile settings for promoting youth’s …

The Effect Of Lps On Phosphorylation Of Akt Signaling In Schwann Cells, Nicholas Wilde, Angela Asirvatham

SURF Posters 2023

Schwann cells (SCs) are cells in the peripheral nervous system that may play a significant role in neuronal repair after an injury, however, little is known about their mechanisms on how they do so. In the lab, lipopolysaccharide (LPS), a bacterial endotoxin, is used to stimulate an injury while forskolin, a growth hormone, is used to activate the cAMP pathway. In this experiment, the cAMP pathway, which is involved in many cellular processes, and protein kinase b (AKT), a cell survival signal, where analyzed in different LPS doses (0.1, 1, and 10 µg/mL) and over different time periods (3-,6-,12-, and …

Electronic Resources Updates - 2022 Q4, Melanie Mcgurr, Gregg Harris

Electronic Resources Quarterly Updates

No abstract provided.

Badges And Blush: Gender Expression In Policework, Aubrey Powell

Williams Honors College, Honors Research Projects

Gender roles are a social construct ingrained in American culture. Stemming from this problem is the femininity versus competency bind. This means that women in the workplace are seen as either feminine or competent, but never both. The purpose of this study was to determine whether the perceived deficit is due to gender expression or biological sex. Additionally, the project examined the masculine of policework and the neutral profession of teaching. Participants were assigned to one of four conditions (feminine woman, masculine woman, feminine man, and masculine man) in which they rated a potential hire for a police precinct or …

Nicotine And E-Cigarette Effect On Maximal Metabolic Rate (Mmr) In Procambarus Clarkii, Nathan Cuttica

Williams Honors College, Honors Research Projects

The use of electronic cigarettes, commonly referred to as e-cigarettes or vapes, has increased exponentially in recent years despite the lack of research into potentially negative physiological effects. The rise in e-cigarette use is likely due to the overwhelming evidence regarding the addictive properties of nicotine and the damage caused by traditional tobacco cigarettes. Most e-cigarettes, however, still contain nicotine and are associated with a rise in nicotine-related intoxications (Belkoniene et al., 2019). There are nicotine-free e-cigarette options, which are gaining popularity, but it is unknown if they carry similar or other negative physiological effects. Studies involving e-cigarettes containing nicotine …

The Effects Of Sex On Zebrafish Bone Metabolism, Simon Bagatto

Williams Honors College, Honors Research Projects

I investigated the effects of diet and sex on zebrafish bone metabolism. Zebrafish were subjected to either a high-calorie or low-calorie diet over a five-week period. After this diet, zebrafish scales were used to measure alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP) enzyme activity with a fluorescent substrate. The enzyme activities were markers of the osteoblasts (ALP) and the osteoclasts (TRAP). These data were compared among sex and diet of the zebrafish using a repeated measures ANOVA statistical test. I also measured the number of resorption lacunae per scale (another indicator of osteoclast activity). The results showed higher TRAP …

How Akron Affects The Water Quality Of The Cuyahoga River, Allyson Darst

Williams Honors College, Honors Research Projects

The purpose of this study was to analyze whether the city of Akron had negative effects on the Cuyahoga river, and determine if the Cuyahoga River was naturally able to remediate these effects downstream. The pollutants measured in this study include hardness, bromine, residual chlorine, iron, copper, lead, nitrate, nitrite, ammonium chloride, total chlorine, fluoride, carbonate, pH, total alkalinity and cyanuric acid. This study was done using water testing strips (JNW Direct) to test the water at four different locations along the Cuyahoga River downstream (North) of Akron. This study found that the city of Akron does have a negative …

Mystic Writers: Religion From A Perspective Of Gender In The Poetry Of St. Teresa Of Avila And St. John Of The Cross, Megan Swope

Williams Honors College, Honors Research Projects

Religion and the way in which people approach it is a complicated topic. There are a multitude of ways in which humans experience religion in their lives. Christian mysticism is a type of thought within the Christian religion, and it is evident in the works of two Spanish writers – Teresa of Avila and John of the Cross. These two saints are good examples to study because, as writers and mystics, they worked closely together in the Spanish Catholic Church and had similar religious beliefs. Much of their writings tie into the same Biblical ideas, while their poetry demonstrates a …

Amphisbaenian Head Movement And Burrowing Forces In Damp Granular Media, Jacob Newell

Williams Honors College, Honors Research Projects

Damp granular media is a difficult environment to study because it is both practically complex and it lacks equations which fully describe its behavior. In this study, an oscillatory lateral head movement and its effects while penetrating damp granular media were tested using a robophysical model. This experimental research was inspired by the burrowing behavior of the clade Amphisbaenia, a group of usually limbless squamates that employ a variety of different burrowing behaviors, but it can apply to a wide range of burrowers. This research could help with both human burrowing technologies and the further investigation of animal behaviors.

Research News, Publications, 2023, Volume 2, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of April 1 through June 30, 2023

Research News, Publications, 2023, Volume 3, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of July 1 through September 30, 2023

Research News, Publications, 2023, Volume 4, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of October 1 through December 31, 2023

Sustainability And Biomimicry, Tabitha Cooper

Williams Honors College, Honors Research Projects

Standardization of business management systems is a vital part of the economic climate, as it allows for fair play between all competitors and encourages growth. The International Organization of Standardization (ISO) independently provides hundreds of standards ranging through dozens of different fields, providing standards applying to topics from quality management to material composition. Not much is readily available on the topics of ISO 9001, which outlines quality management systems (QMS) ISO 14001, which details environmental management systems (EMS), and their relation to ISO 18457, which explains what composes a biomimetic material or product. A literature review was conducted to gather …

Buoyancy And Emergence In Elymus Species, Sandor Jakab

Williams Honors College, Honors Research Projects

It is important that native plants are able to successfully emerge in wetlands because they play an important role in maintaining diversity. The relationship between seed buoyancy and seedling emergence was analyzed for three wetland species of the same genus: Elymus canadensis (FACU), Elymus macgregorii (FACW), and Elymus virginicus (FACW). E. macgregorii seemed to be the most buoyant, and E. virginicus and E. canadensis demonstrated very similar, less buoyant levels. Based on the idea that more buoyant seeds will be deposited at a shallow depth, and less buoyant seeds will be deposited at a deeper soil level, a relationship between …

How Bollywood Has Influenced Cinema And Viewers Both Locally And Globally, Bhumi Patel

Williams Honors College, Honors Research Projects

The evolution and impact of Bollywood cinema follows its journey from silent films to contemporary masterpieces. Bollywood reflects India's rich cultural heritage while adapting to societal shifts and embracing progressive themes. From timeless tales of romance to modern explorations of feminism, LGBTQ+ rights, and mental health, Bollywood has evolved into a dynamic force for social commentary and cultural expression. Through integration of deep emotions and universally enjoyable music and dance, Bollywood transcends language and cultural barriers, captivating audiences worldwide. While facing setbacks such as lack of diversity, Bollywood is gradually embracing inclusivity and evolving with the times. By addressing taboo …

Comparison Of Bone Robustness Between Fore- And Hindlimb In Neonatal And Infant Galago, Jeremy Busken

Williams Honors College, Honors Research Projects

According to Wolff’s law, bone is constantly subject to change based on loading patterns (Ruff et al., 2006). Those subjected to greater stress become more robust by increasing bone mineral density and often changing geometric properties. Previous studies of primate anatomy have found significant differences in bone robustness between the fore- and hindlimbs in adult leaping primates. Because leaping primates, such as Galago senegalensis and Galago moholi, subject their hindlimbs to much greater stress, this difference in robustness may come as a result of bone functional adaptation/Wolff’s law. This study sought to investigate this possibility by testing neonatal and infant …

Finding An Accurate Method To Measure Pollinator Visitation Rates, Claire Struhsaker

Williams Honors College, Honors Research Projects

Pollinator visitation rates are a helpful way to monitor the health of ecosystems; however, there lacks a standardized method for obtaining these rates. The pollinator visitation rates for five plant species were collected and the relationship between the standard error of these rates and the time interval was determined. Monarda, Echinacea purpurea, Pycnanthemum muticum, and Baptisia alba all exhibit more accurate pollinator visitation rates as the time interval increased. Trifolium repens exhibited less accurate pollinator visitation rates as the time interval increased.

The Effectiveness Of Treatments For Drug-Resistant Epilepsy: A Review Of Literature, Lauren Cummons

Williams Honors College, Honors Research Projects

Many studies examine the treatment options for epilepsy; however, there is a lack of reviews compiling and evaluating the current treatments for drug-resistant epilepsy (DRE). This project aims to explore the existing body of research studies completed on treating DRE, evaluate the effectiveness of each treatment option, and assess what areas of research need more attention for future studies. Six primary DRE treatments from current research were thoroughly examined for this review. The quality of each treatment was evaluated based on the number of patients who had seizure freedom, had a seizure reduction, had adverse events, and had changes in …

Get Out: Structural Racism And Academic Terror, Renee Nicole Allen

Faculty Publications

Released in 2017, Jordan Peele’s critically acclaimed film Get Out explores the horrors of racism. The film’s plot involves the murder and appropriation of Black bodies for the benefit of wealthy, white people. After luring Black people to their country home, a white family uses hypnosis to paralyze victims and send them to the Sunken Place where screams go unheard. Black bodies are auctioned off to the highest bidder; the winner’s brain is transplanted into the prized Black body. Black victims are rendered passengers in their own bodies so that white inhabitants can obtain physical advantages and immortality.

Like Get …

Rim-To-Rim Wearables At The Canyon For Health (R2r Watch): Physiological, Cognitive, And Biological Markers Of Performance Decline In An Extreme Environment, Kristin Divis, Robert Abbott, Cathy Branda, Glory Emmanuel-Aviña, Jon Femling, J. Gabriel Huerta, Lucie Jelinková, J. Kyle Jennings, Emily A. Pearce, Daniel Ries, Danielle Sanchez, Austin Silva

Journal of Human Performance in Extreme Environments

Success in extreme environments comes with a cost of subtle performance decrements that if not mitigated properly can lead to lifethreatening consequences. Identification and prediction of performance decline could alleviate deleterious consequences and enhance success in challenging and high-risk operations. The Rim-to-Rim Wearables at the Canyon for Health (R2R WATCH) project was designed to examine the cognitive, physiological, and biological markers of performance decline in the extreme environment of the Grand Canyon Rim-to-Rim (R2R) hike. The study utilized commercial off-the-shelf cognitive and physiological monitoring techniques, along with subjective self-assessments and hematologic measurements to determine subject performance and changes across the …

The Perspective Of Care Providers About Barriers To Medication Adherence Among Asian, Chanraksmey Hok

Doctor of Nursing Practice Projects

Background: Asian Americans form a growing part of American society, and it is critical to address the mental health challenges of this growing population. Due to the minority status of this community, limited information is available regarding the details of unique issues experienced by members of this community in accessing and continuing treatment for mental health disorders. Depression is a critical high-prevalence mental health illness affecting Asian Americans, and low depression medication adherence is an important factor in this illness remaining undertreated in community members. Understanding the barriers to depression medication adherence for Asian Americans is thus critical to effectively …

“Beggars Can’T Be Choosers”: Individual Experiences And Career Planning Attitudes Among Female Doctoral Students In Europe, Gintarė Lübeck

Conference papers

This study investigates the career aspirations of female PhD students and recent graduates in Europe, and the decisions they made, with a focus on the reasons behind the increasing departure of female academics from academia after the completion of their doctoral studies. Qualitative data from interviews with 15 female PhD students at different stages of their doctoral journeys provided insights into the uncertainties experienced by these women regarding their future in academia. The findings revealed that these uncertainties stemmed from a combination of factors, including challenging experiences encountered during their PhD programmes, perceptions of gender and cultural biases within their …

Secondary Traumatic Stress And Women Music Educators: A Phenomenological Study, Abigail Van Klompenberg

Theses and Dissertations--Music

Secondary traumatic stress (STS) is a phenomenon that affects individuals in helping professions, including educators. STS is a trauma disorder and results from one’s exposure to others experiencing trauma or who have experienced trauma. STS can affect physical health, well-being, and professional performance. Due to the profound effects of STS, there is a need for continued research to clarify this phenomenon in educators, specifically music educators. Furthermore, there is a need for research on STS in women due to women’s unique interactions with trauma and the potential for them to develop trauma disorders. At the time of this study, there …

Mammalian Dihydropyrimidine Dehydrogenase: Employing Transient State Kinetic Methods To Determine Catalytic And Inhibitory Mechanisms, Dariush Forouzesh

Dissertations

Dihydropyrimidine dehydrogenase (DPD) catalyzes the two-electron reduction of pyrimidine bases uracil and thymine as the first step in pyrimidine catabolism. The enzyme achieves this simple chemistry using a complex cofactor set including two flavins and four Fe4S4 centers. The flavins, FAD and FMN, interact with respective NADPH and pyrimidine substrates and the iron-sulfur centers form an electron transfer wire that links the two active sites that are separated by 56 Å. DPD accepts the common antineoplastic agent 5-fluorouracil (5FU) as a substrate and so undermines the establishment of efficacious toxicity. Though studied for multiple decades, a precise description of the …