Digital Commons Network^™

Parnassus 2023

Parnassus

The 2023 edition of the student literary journal, Parnassus, published by Taylor University in Upland, Indiana.

Annual Report Of The Wally Cordes Teaching And Faculty Support Center For The Year Ended...2023, University Of Arkansas, Fayetteville. Wally Cordes Teaching And Faculty Support Center

Wally Cordes Teaching and Faculty Support Center Annual Report

No abstract provided.

Characteristics Of Gingival Crevicular Fluid Flow During Orthodontic Treatment With Invisalign, Nina Stevens

Orthodontics and Endodontics Theses

OBJECTIVES. Studies on quantitative relationships between magnitude of force applied to a tooth root and formation of gingival crevicular fluid (GCF) biomarkers (volume, concentrations of cytokines, enzymes, etc.) in clinical settings are lacking. This study aims to answer the question: What can analysis of GCF flow dynamic characteristics inform us about orthodontic tooth movement in a patient treated by Invisalign? METHODS. In three participants, two GCF samples were collected from five maxillary and five mandibular teeth during start, middle and end of Invisalign treatment. Plaque index and pocket depths were determined. Periopaper strips (Oraflow) were used for collection of GCF, …

Pharmacology For National Board Examination, Krina Shah

Dugoni School of Dentistry Student Scholarly Works

This pharmacology study guide is designed to provide students preparing for the National Boards exam with a clear and concise visual aid in the form of systemic flow charts. Each flow chart is organized by drug class and includes information on the mechanism of action, indications, contraindications, dosages, and common adverse effects for each drug within the class. By using this study guide, students can easily navigate through the complex world of pharmacology and feel confident in their ability to succeed on the pharmacology section of the National Board exam. The study guide for pharmacology is significant in several ways. …

Chronic Environmental Circadian Disruption Increases Atherosclerosis And Dyslipidemia In Female, But Not Male, Apolipoproteine-Deficient Mice, Jeffrey M. Chalfant, Deborah A. Howatt, Victoria B. Johnson, Lisa R. Tannock, Alan Daugherty, Julie S. Pendergast

Teacher Education and Certification Faculty Research & Creative Works

Shift work chronically disrupts circadian rhythms and increases the risk of developing cardiovascular disease. However, the mechanisms linking shift work and cardiovascular disease are largely unknown. The goal of this study was to investigate the effects of chronically shifting the light-dark (LD) cycle, which models the disordered exposure to light that may occur during shift work, on atherosclerosis. Atherosclerosis is the progressive accumulation of lipid-filled lesions within the artery wall and is the leading cause of cardiovascular disease. We studied ApolipoproteinE-deficient (ApoE−/−) mice that are a well-established model of atherosclerosis. Male and female ApoE−/− mice were housed in control 12L:12D …

Undergraduate Catalogue 2023 - 2024, Tennessee State University

Tennessee State University Undergraduate Catalogues

No abstract provided.

Nanomaterials-Based Biosensors For The Detection Of Prostate Cancer Biomarkers: Recent Trends And Future Perspective, Baljit Singh, Shiliang Ma, Tony O. Hara, Sargun Singh

Articles

Cancer is among the leading causes of death and an important barrier to improving life expectancy globally. Prostate cancer is the second most common cancer in men worldwide. The detection of biomarkers in body fluids is the key topic for the diagnosis and prognosis of prostate cancer. Despite advances in prostate cancer detection methods, therapeutic agents and new biomarkers, prostate cancer remains a serious challenge. Prostate-specific antigen (PSA) is widely recognized as an important biomarker for the diagnosis of prostate cancer although researchers have also investigated the use of alternative biomarkers. Design and development of novel biosensors for prostate cancer …

Yale School Of Medicine Facts & Figures 2023-2024, Yale School Of Medicine Office Of Communications

Facts & Figures – annual Yale School of Medicine numbers

Provided by the Office of Communications, the Facts and Figures brochure is produced annually as a way to provide a snapshot of key facts and data related to the School of Medicine as well as the Medical Campus. This includes enrollment data, research activity, financial summaries, and more.

The Autism Symptom Dimensions Questionnaire: Development And Psychometric Evaluation Of A New, Open-Source Measure Of Autism Symptomatology, Thomas Frazier, Anastasia Dimitropoulos, Leonard Abbeduto, Melissa Armstrong-Brine, Shanna Kralovic, Andy Shih, Antonio Y. Hardan, Eric A. Youngstrom, Mirko Uljarević

2023 Faculty Bibliography

Aim: To describe the development and initial psychometric evaluation of a new, freely available measure, the Autism Symptom Dimensions Questionnaire (ASDQ).

Method: After development and revision of an initial 33-item version, informants completed a revised 39-item version of the ASDQ on 1467 children and adolescents (aged 2-17 years), including 104 with autism spectrum disorder (ASD).

Results: The initial 33-item version of the ASDQ had good reliability and construct validity. However, only four specific symptom factors were identified, potentially due to an insufficient number of items. Factor analyses of the expanded instrument identified a general ASD factor and nine specific symptom …

Profiles Of Circumscribed Interests In Autistic Youth, Emily Spackman, Luke D. Smillie, Thomas Frazier, Antonio Y. Hardan, Gail A. Alvarez, Andrew Whitehouse, Mirko Uljarević

2023 Faculty Bibliography

Circumscribed interests (CI) encompass a range of different interests and related behaviors that can be characterized by either a high intensity but otherwise usual topic [referred to as restricted interests (RI)] or by a focus on topics that are not salient outside of autism [referred to as unusual interests (UI)]. Previous research has suggested that there is pronounced variability across individuals in terms of the endorsement of different interests, however, this variability has not been quantified using formal subtyping approaches. Therefore, using Latent Profile Analysis in a sample of 1,892 autistic youth (Mage = 10.82, SDage = 4.14; 420 females), …

Protected Areas Slow Declines Unevenly Across The Tetrapod Tree Of Life, A Justin Nowakowski, James I. Watling, Alexander Murray, Jessica L. Deichmann, Thomas S. Akre, Carlos L. Muñoz Brenes, Brian D. Todd, Louise Mcrae, Robin Freeman, Luke O. Frishkoff

2023 Faculty Bibliography

Protected areas (PAs) are the primary strategy for slowing terrestrial biodiversity loss. Although expansion of PA coverage is prioritized under the Convention on Biological Diversity, it remains unknown whether PAs mitigate declines across the tetrapod tree of life and to what extent land cover and climate change modify PA effectiveness1,2. Here we analysed rates of change in abundance of 2,239 terrestrial vertebrate populations across the globe. On average, vertebrate populations declined five times more slowly within PAs (−0.4% per year) than at similar sites lacking protection (−1.8% per year). The mitigating effects of PAs varied both within and across vertebrate …

New Terrestrial Cyanobacteria From The Azores Islands: Description Of Venetifunis Gen. Nov. And New Species Of Albertania, Kovacikia And Pegethrix, Ruben Luz, Rita Cordeiro, Jan Kastovsky, Jeffrey R. Johansen, Elisabete Dias, Amelia Fonseca, Vitor Vasconcelos, Vitor Goncalves

2023 Faculty Bibliography

The taxonomy of cyanobacteria has advanced quickly with the use of molecular methods in combination with well-defined morphological and ecological characters. Using this approach, many taxonomical changes have occurred in the Synechococcales and Oscillatoriales, with the description of new families, genera and species. Here we present the study of four cyanobacterial strains from the Bank of Algae and Cyanobacteria of the Azores (BACA) culture collection, all isolated from the Azores Archipelago. The strains were genetically characterized through the amplification of the 16S rRNA gene and 16S-23S rRNA internal transcribed spacer (ITS) region, as well as morphologically by light and transmission …

Linking Predator Responses To Alkaloid Variability In Poison Frogs Language:, J P. Lawrence, Bibiana Rojas, Annelise Blanchett, Ralph Saporito, Johanna Mappes, Antoine Fouquet, Brice P. Noonan

2023 Faculty Bibliography

Many chemically-defended/aposematic species rely on diet for sequestering the toxins with which they defend themselves. This dietary acquisition can lead to variable chemical defenses across space, as the community composition of chemical sources is likely to vary across the range of (an aposematic) species. We characterized the alkaloid content of two populations of the Dyeing Poison Frog (Dendrobates tinctorius) in northeastern French Guiana. Additionally, we conducted unpalatability experiments with naive predators, Blue Tits (Cyanistes caeruleus), using whole-skin secretion cocktails to assess how a model predator would respond to the defense of individuals from each population. While there was some overlap …

Maternal Chemical Defenses Predict Ofspring Defenses In A Dendrobatid Poison Frog, Olivia L. Brooks, Jessie J. James, Ralph Saporito

2023 Faculty Bibliography

Within and among populations, alkaloid defenses of the strawberry poison frog (Oophaga pumilio) vary spatially, temporally, and with life history stage. Natural variation in defense has been implicated as a critical factor in determining the level of protection aforded against predators and pathogens. Oophaga pumilio tadpoles sequester alkaloids from nutritive eggs and are, thus, entirely dependent on their mothers for their defense. However, it remains unclear how tadpole alkaloid composition relates to that of its mother and how variation in maternally provisioned defenses might result in varying levels of protection against predators. Here, we demonstrate that natural variation in the …

Development Of Webcam-Collected And Artificial- Intelligence-Derived Social And Cognitive Performance Measures For Neurodevelopmental Genetic Syndromes, Thomas Frazier, Robyn M. Busch, Patricia Klaas, Katherine Lachlan, Shafali Jeste, Alexander Kolevzon, Eva Loth, Jacqueline Harris, Leslie Speer, Tom Pepper, Kristin Anthony, J Michael Graglia, Christal G. Delagrammatikas, Sandra Bedrosian-Sermone, Constance Smith-Hicks, Katie Huba, Robert Longyear, Leeann Green-Snyder, Frederick Shic, Mustafa Sahin, Charis Eng, Antonio Y. Hardan, Mirko Uljarevic

2023 Faculty Bibliography

This study focused on the development and initial psychometric evaluation of a set of online, webcam-collected, and artificial intelligence-derived patient performance measures for neurodevelopmental genetic syndromes (NDGS). Initial testing and qualitative input was used to develop four stimulus paradigms capturing social and cognitive processes, including social attention, receptive vocabulary, processing speed, and single-word reading. The paradigms were administered to a sample of 375 participants, including 163 with NDGS, 56 with idiopathic neurodevelopmental disability (NDD), and 156 neurotypical controls. Twelve measures were created from the four stimulus paradigms. Valid completion rates varied from 87 to 100% across measures, with lower but …

Albertania And Egbenema Gen. Nov. From Nigeria And The United States, Expanding Biodiversity In The Oculatellaceae (Cyanobacteria), Mildred Akagha, Nicole Pietrasiak, David F. Bustos, Alžběta Vondrášková, Sandra C. Lamb, Jeffrey R. Johansen

2023 Faculty Bibliography

Knowledge of the tropical terrestrial cyanobacterial flora from the African con-tinent is still limited. Of 31 strains isolated from soil and subaerial samples col-lected in Lagos State, Nigeria, three were found to be in the Oculatellaceae,including two species in a new genus. Subsequently, isolates from micro-bial mats in White Sands National Park in New Mexico, United States, andfrom a rock near the ocean in Puerto Rico, United States, were found tobelong to the new genus as well. Cyanobacterial isolates were character-ized microscopically, sequenced for the 16S rRNA gene and associated ITSregion, and phylogenetically analyzed. Egbenema gen. nov., with three newspecies, …

Investigating Peptide Folding Of Tryptophan Zippers, Chad Tatko, Jessica Bedow, Kachel Bedow, Maddy Hoogstra, Douglas Vander Griend

Summer Research

Protein folding has been a subject of interest in the research community for its wide array o f applications in academia and medicine. By understanding how the interaction of localized amino acids in different environmental factors affect the global folding of peptides, one can anticipate synthesis of proteins or manipulation of exis ting pro teins to have more desirable functions. For this investigation, tryptophan zippers (monomeric β-hairpin peptides) were synthesized, titrated in differing pH, and analyzed by NMR

The Emma Cole Grand Rapids Flora Project: Documenting And Assessing Change 123 Years Later, Elliott Stob, Renee Figueroa, Garrett Crow, David Warners

Summer Research

In 1901, botanist, teacher, and Kent Scientific Institute scientist, Emma J. Cole published her book Grand Rapids Flora: A Catalogue of the Flowering Plants and Ferns Growing Without Cultivation in the Vicinity of Grand Rapids, Michigan. For over 100 years her book has provided an excellent perspective into the natural environment of the area. The aim of the project is to revisit and inventory sites she explored, as well as other remnant natural areas, to see how plant life has changed over the past 120+ years.

Beginning in 2015 the project has assessed 54 sites, mentored 19 students, discovered …

Higher Sexual Excitation Is Associated With An Increase In Sex-Linked Substance Use In Women With A History Of Unwanted Sexual Contact, Harper R. Jones, Tierney K. Lorenz

Center for Brain, Biology, and Behavior: Faculty Publications

Survivors of unwanted sexual contact have an increased likelihood of using substances in sexual situations, which puts them at heightened risk for intoxication-related harms. Separately, research has indicated that women may intentionally use substances in sexual situations to either enhance pleasure (i.e., increase sexual excitation) and/or reduce sexual anxiety or shame (i.e., reduce sexual inhibition), a phenomenon termed sex-linked substance use (SLSU). A predominant assumption in the literature is that women with unwanted sex histories are more likely to disengage during sex, suggesting greater inhibition-related SLSU; however, there is little prior research directly examining if women who have unwanted sex …

Pre–Post Intervention Exploring Cognitive Function And Relationships With Weight Loss, Intervention Adherence And Dropout, Amanda N. Szabo-Reed, Laura E. Martin, Cary R. Savage, Richard A. Washburn, Joseph E. Donnelley

Center for Brain, Biology, and Behavior: Faculty Publications

Objective: To evaluate the association between baseline cognitive function, intervention dropout, adherence and 3-month weight loss (WL) when controlling for confounding demographic variables.

Methods: 107 (Mage = 40.9 yrs.), BMI in the overweight and obese range (BMI = 35.6 kg/m2), men (N = 17) and women (N = 90) completed a 3-month WL intervention. Participants attended weekly behavioral sessions, comply with a reduced calorie diet, and complete 100 min of physical activity (PA)/wk. Cognitive function tasks at baseline included Flanker (attention), Stroop (executive control) and working memory, demographics, body weight and cardiovascular fitness were assessed at baseline. Session attendance, adherence …

Concussion-Related Disruptions To Hub Connectivity In The Default Mode Network Are Related To Symptoms And Cognition, Heather C. Bouchard, Kate L. Higgins, Grace Amadon, Julia M. Laing-Young, Arthur C. Maerlender, Seima Al-Momani, Maital Neta, Cary R. Savage, Douglas H. Schultz

Center for Brain, Biology, and Behavior: Faculty Publications

Concussions present with a myriad of symptomatic and cognitive concerns; however, the relationship between these functional disruptions and the underlying changes in the brain are not yet well understood. Hubs, or brain regions that are connected to many different functional networks, may be specifically disrupted after concussion. Given the implications in concussion research, we quantified hub disruption within the default mode network (DMN) and between the DMN and other brain networks. We collected resting-state functional magnetic resonance imaging data from collegiate student-athletes (n = 44) at three timepoints: baseline (prior to beginning their athletic season), acute post-injury (approximately 48 hours …

A Long‐Term Obesogenic High‐Fat Diet In Mice Partially Dampens The Anti‐Frailty Benefts Of Late‐Life Intermittent Fasting, Yoko Henderson, Nazmin Bithi, Jie Yang, Christopher Link, Aili Zhang, Benjamin Baron, Eran Maina, Christopher Hine

Senior Honors Projects

The global obesity pandemic coupled with ever-growing life expectancies equates to hundreds of millions of individuals with potentially longer but not healthier lives. Aging is one of the risk factors for numerous maladies such as metabolic dis- order and frailty, which are exacerbated under obesity. Thus, therapeutic approaches that address obesity to ultimately improve afected individuals’ quality of life and extend their lifespan are needed. We previously reported that the every other day (EOD) fasting initiated late-life improved metabolic, musculoskeletal, and cognitive endpoints in standard rodent diet-fed mice. In the present study, using the same dietary intervention methodology, we tested …

Dead Reckoning: A Multiteam System Approach To Commentaries On The Drake-S Equation For Survival, James Houran, Adam J. Rock, Brian Laythe, Patrizio E. Tressoldi

International Journal of Transpersonal Studies

We used a multiteam system approach (MTS) to map the critical and constructive feedback from four invited Commentaries on Rock et al.’s (2023) probabilistic analysis of purported evidence for postmortem survival. The goal was to mine actionable insights to guide future research with the potential for important learnings or breakthroughs about the nature or limits of human consciousness and their relation to transpersonal psychology. The commentators’ input identified only a few measurable variables or empirical tactics that conceivably challenge or refine our latest Drake-S Equation for survival. However, a review of these suggestions using logical and statistical criteria revealed that …

Continuities Of Consciousness, Life-Worlds, And Numinous Experience: Cognitive-Phenomenological Foundations For An Empirical Neo-Shamanism, Harry T. Hunt

International Journal of Transpersonal Studies

Numinous experience—as the felt sense of the sacred—evokes feelings of allone unity, communality, humility, and healing. Its schematization in the absolutes of traditional religion can also be seen as all-encompassing symbolic unifications of an otherwise fragmented human life-world—as more analytically depicted in the life-world phenomenologies of Husserl and Heidegger. In both feeling and concept the numinous would be the semantic amplification of the more concrete organism-surround nonduality of non symbolic organisms—as reflected in a primary consciousness shared across Uexkuell’s sentient animal umwelten and Gibson’s “envelopes of flow.” H usserl’s phenomenology of passive synthesis and James on pure experience can be …

“We Are Now The Owners Of The Land” Black Homesteading And The Rise Of Political Participation In Kingfisher County, Oklahoma, 1889–1907, Heidi Dodson, Kalenda Eaton

Center for Great Plains Studies: Staff and Fellows Publications

This article expands on recent scholarship uncovering the experience of Black homesteaders in Oklahoma Territory in the late 19th century. Drawing on census records, newspapers, and homesteading land entry case files, it spotlights the stories of families who successfully proved claims in Kingfisher County while becoming public figures in political and civic circles. Examples include Doctor B. Garrett and Anthony Overton Jr., who in some ways were atypical homesteaders because they were prominent in public life and farmers. Yet they are representative of hundreds of Oklahoma Black homesteaders in their dreams of owning property, voting, and building communities in a …

Collaborative Fisheries Research Reveals Reserve Size And Age Determine Efficacy Across A Network Of Marine Protected Areas, Shelby L. Ziegler, Rachel O. Brooks, Lyall F. Bellquist, Jennifer E. Caselle, Steven G. Morgan, Timothy J. Mulligan, Benjamin I. Ruttenberg, Brice X. Semmens, Richard M. Starr, Joe Tyburczy, Dean E. Wendt, Andre Buchheister, Jose R. Marin Jarrin, Christina Pasparakis, Salvador J. Jorgensen, Jennifer A. Chiu, Jordan Colby, Connor L. Coscino, Leon Davis, Francine De Castro, Jack T. Elstner, Christopher Honeyman, Erica T. Jarvis Mason, Erin M. Johnston, Sadie L. Small, Jay Staton, Grant T. Waltz, Bonnie Basnett, Erin V. Satterthwaite, Helen Killeen, Connor D. Dibble, Scott L. Hamilton

Marine Science Faculty Publications and Presentations

A variety of criteria may influence the efficacy of networks of marine protected areas (MPA) designed to enhance biodiversity conservation and provide fisheries benefits. Meta-analyses have evaluated the influence of MPA attributes on abundance, biomass, and size structure of harvested species, reporting that MPA size, age, depth, and connectivity influence the strength of MPA responses. However, few empirical MPA evaluation studies have used consistent sampling methodology across multiple MPAs and years. Our collaborative fisheries research program systematically sampled 12 no-take or highly protective limited-take MPAs and paired fished reference areas across a network spanning 1100 km of coastline to evaluate …

Differences In The Behavior And Diet Between Shoaling And Solitary Surgeonfish (Acanthurus Triostegus), Ana Sofia Guerra, Jacey C. Van Wert, Alison J. Haupt, Douglas J. Mccauley, Erika J. Eliason, Hillary S. Young, David Lecchini, Timothy D. White, Jennifer E. Caselle

Marine Science Faculty Publications and Presentations

Variation in behavior within marine and terrestrial species can influence the functioning of the ecosystems they inhabit. However, the contribution of social behavior to ecosystem function remains underexplored. Many coral reef fish species provide potentially insightful models for exploring how social behavior shapes ecological function because they exhibit radical intraspecific variation in sociality within a shared habitat. Here, we provide an empirical exploration on how the ecological function of a shoaling surgeonfish (Acanthurus triostegus) may differ from that of solitary conspecifics on two Pacific coral reefs combining insight from behavioral observations, stable isotope analysis, and macronutrient analysis of gut and …

Connectivity Between White Shark Populations Off Central California, Usa And Guadalupe Island, Mexico, Paul E. Kanive, Jay J. Rotella, Taylor K. Chapple, Scot D. Anderson, Mauricio Hoyos-Padilla, Abbott Peter Klimley, Felipe Galván-Magaña, Samantha Andrzejaczek, Barbara A. Block, Salvador J. Jorgensen

Marine Science Faculty Publications and Presentations

Marine animals often move beyond national borders and exclusive economic zones resulting in a need for trans-boundary management spanning multiple national jurisdictions. Highly migratory fish vulnerable to over-exploitation require protections at international level, as exploitation practices can be disparate between adjacent countries and marine jurisdictions. In this study we collaboratively conducted an analysis of white shark connectivity between two main aggregation regions with independent population assessment and legal protection programs; one off central California, USA and one off Guadalupe Island, Mexico. We acoustically tagged 326 sub-adult and adult white sharks in central California (n=210) and in Guadalupe Island (n=116) with …

Baseline Skin Cytokine Profiles Determined By Rna In Situ Hybridization Correlate With Response To Dupilumab In Patients With Eczematous Dermatitis, Katelyn Singh

Yale Medicine Thesis Digital Library

Dupilumab, a monoclonal antibody that inhibits IL4 and IL13, has revolutionized the treatment of atopic dermatitis (AD). However, not all patients respond optimally, and this may relate to underlying molecular heterogeneity. Yet, clinically useful and accessible methods to assess such heterogeneity have not been developed. Additionally, As the number of targeted medications continues to expand, the choice of which specific therapy to initiate in any individual patient will become increasingly difficult. Currently, there are no biomarkers that can be used to guide treatment selection in common inflammatory diseases such as atopic dermatitis (AD) and psoriasis. This study aims to determine …

Understanding Student Experiences Of Renewable And Traditional Assignments, Virginia Clinton-Lisell, Lindsey Gwozdz

Education, Health & Behavior Studies Faculty Publications

Renewable assignments are student created artifacts that have value outside of courses. However, more empirical inquiry in renewable assignments grounded in theoretical frameworks is necessary. In this study, students (N = 69) engaged in renewable assignments and were asked to report on their perceptions based on the self-determination theory of motivation and social justice principles. Overall, students reported higher levels of motivation as well as more opportunity to represent their identities for renewable assignments than traditional assignments. Students who opted to publicly share reported higher levels of competence and relatedness than did students who did not opt to publicly share.