Digital Commons Network^™

Proteomic Quantification Of Receptor Tyrosine Kinases Involved In The Development And Progression Of Colorectal Cancer Liver Metastasis, Areti-Maria Vasilogianni, Zubida M. Al-Majdoub, Brahim Achour, Sheila Annie Peters, Amin Rostami-Hodjegan, Jill Barber

Biomedical and Pharmaceutical Sciences Faculty Publications

Introduction: Alterations in expression and activity of human receptor tyrosine kinases (RTKs) are associated with cancer progression and in response to therapeutic intervention.

Methods: Thus, protein abundance of 21 RTKs was assessed in 15 healthy and 18 cancerous liver samples [2 primary and 16 colorectal cancer liver metastasis (CRLM)] matched with non-tumorous (histologically normal) tissue, by a validated QconCAT-based targeted proteomic approach.

Results: It was demonstrated, for the first time, that the abundance of EGFR, INSR, VGFR3 and AXL, is lower in tumours relative to livers from healthy individuals whilst the opposite is true for IGF1R. EPHA2 was upregulated in …

Arkansas Razorback Men's Golf Record Book, 2022-2023, University Of Arkansas, Fayetteville. Athletics Media Relations

Arkansas Men's Golf

No abstract provided.

Effects Of Plastic And Waste Pollution On Ocean Communities In The Asian Pacific Region, Whitney Kingsolver

Ballard Brief

Plastic and waste pollution is a global problem, but it affects ocean communities in the Asia Pacific Region (APR) the most due to their lack of resources to process the pollution. Additionally, low-income areas in these countries need access to sustainable non-plastic packaging options, which increases the amount of plastic generated. Direct pollution leads to poor ocean health and the disruption of important industries like tourism or fishing. Plastic pollutants eventually break down, which creates microplastics and releases toxic chemicals. These pollutants damage ecosystems and severely harm marine life. The overwhelming amount of waste pollution in the APR also damages …

“Popping It” As Family In Mosquitoes & Me: Affective Accumulation And Anzaldúan Aesthetic Consciousness In Ciencia Zurda, Katherine R. Bruna, Jennifer Farley, Lyric Bartholomay

University of Nebraska Public Policy Center: Publications

This article uses key concepts of Anzaldúan philosophy to describe the Mosquitoes & Me summer camp as ciencia zurda or left-handed science. It details a day-in-the-life portrait of Elena, a first-generation Latina middle schooler, as she experiences the opportunities that Mosquitoes & Me provided for self-other bridge crossing and radically relational, Nepantlan potential. Our discussion of Elena’s experiences in terms of Nepantlan principles of diversity, Affect, and spirit, as well as Affective accumulation and aesthetic consciousness, infuse an emotional and spiritual dimension to inquiry science- and responsive sciencecomplementarity and revisit a call for soul-centered, socially-transformative science.

Este artículo utiliza conceptos …

26th Asc Of Icsm Abstracts

Journal of the Hong Kong College of Cardiology

No abstract provided.

High Sensitivity Of The Tiger Beetle, Cicindela Circumpicta, To Toxicity From Pyrethroids And Neonicotinoids, And Implications For Ecosystem Function And Species Extinctions, S. Svehla, T. Brosius, Leon Higley, T. Hunt

School of Natural Resources: Faculty Publications

No abstract provided.

Microplastics In Wetlands Of West Central Ohio : Concentration And Distribution, Mitchell Link

Browse all Theses and Dissertations

Wetlands provide many valuable ecosystem services; however, an emerging global contaminant—microplastic (< 5 mm)—may be degrading this important resource. Few studies have extensively surveyed microplastic distribution in wetlands over a broad spatial area. Therefore, the goal of this study is to identify where microplastics are accumulating in wetlands, and whether there is any correlation between microplastic concentration and wetland quality. Soil samples were collected from 30 wetlands in west–central Ohio. Samples were physically separated, density separated, and digested. Average microplastic concentrations were 637 ± 494 items per kg soil per wetland. Higher quality wetlands are accumulating larger concentrations of microplastics. This relationship seems to be driven by greater accumulation of microplastics in forested wetlands than in wetlands surrounded by agriculture. There is no clear distribution pattern of microplastics within wetlands. These results provide insight into the role that wetlands have in association with microplastic accumulation.

Efficient Cloud-Based Ml-Approach For Safe Smart Cities, Niveshitha Niveshitha

Browse all Theses and Dissertations

Smart cities have emerged to tackle many critical problems that can thwart the overwhelming urbanization process, such as traffic jams, environmental pollution, expensive health care, and increasing energy demand. This Master thesis proposes efficient and high-quality cloud-based machine-learning solutions for efficient and sustainable smart cities environment. Different supervised machine-learning models for air quality predication (AQP) in efficient and sustainable smart cities environment is developed. For that, ML-based techniques are implemented using cloud-based solutions. For example, regression and classification methods are implemented using distributed cloud computing to forecast air execution time and accuracy of the implemented ML solution. These models are …

Effects Of Phosphorus-Binding Agents On Nutrient Dynamics And A Planktothrix Bloom In A Shallow, Semi-Enclosed Lake Area, Joseph Lee Davidson

Browse all Theses and Dissertations

Grand Lake St. Marys is the largest (52 km2) inland lake in Ohio, USA, and receives high nutrient loadings (90th percentile for total nitrogen (N) and phosphorus (P) concentrations in the USA) from a watershed dominated by agricultural row-crops and livestock production. Eutrophication has led to cyanobacterial harmful algal blooms, dominated by non-N2 fixing Planktothrix, that persist year-round, including in winter months. In summer 2020 and 2021, multiple treatments using P-binding agents within a 3.5 ha swimming enclosure were conducted to remove excess dissolved P from the water column. The objective of this study was to examine pre-and-post treatment biogeochemical …

Utilization Of Physiological Based Pharmacokinetic Modeling To Predict Systemic Exposure And Guide Dosing Decisions For Therapeutic Drug Monitoring Of Beta-Lactams In Critically Ill Patients, Hui Wei

Selected Full-Text Dissertations 2020-

Sepsis leads to a continuous pathophysiologic process that dysregulates host response which potentially causes significant organ damage and even death, especially respiratory, renal and cardiac failure. Changes in the clearance and volume of distribution are typically result in pharmacokinetic variabilities and often make it challenging for clinicians to appropriately dose beta-lactam antibiotics. Therapeutic drug monitoring (TDM) is necessary to further optimize beta-lactam pharmacokinetic/pharmacodynamic (PK/PD) parameters to improve clinical outcomes and reduce therapeutic failure.

Cefepime (CEF) and meropenem (MEM) primarily excreted by the kidney, and altered the kidney function of the ICU patients would affect the clearance of the medications. On …

U2.38.70_Ta3 06.17.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.31.1038_Ta3 06.14.21 Prox. Humerus.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.31.106_Ta3 06.22.21 Dist. Humerus.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.60_Ta3 06.18.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.740_Ta3 06.18.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.31.338_Ta3 06.22.21 Dist. Humerus.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.54_Ta3 06.18.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.133_Ta3 06.17.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.615_Ta3 06.17.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.503_Ta3 06.17.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U1.31.213_Ta3 06.14.21 Prox. Humerus.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U1.31.301_Ta3 06.14.21 Prox. Humerus.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.432_Ta3 06.17.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.316_Ta3 06.17.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.315_Ta3 06.17.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.327_Ta3 06.18.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.546_Ta3 06.18.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.281_Ta3 06.17.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.38.282_Ta3 06.18.21 Femora.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …

U2.37.898_Ta3 06.24.21 Ps.Ta3, Alyssa Bolster, Hannah Jeanlouis

Bolster et al. 2024 AJBA

Objectives We estimate adult age distributions from Unar 1 and Unar 2, two late Umm an-Nar (2400-2100 BCE) tombs in the modern-day Emirate of Ras al-Khaimah, United Arab Emirates. These collective tombseach contained hundreds of skeletons in commingled, fragmented, and variably cremated states. Previous studies placed the vast majority of this mortuary community in a generalized “adult” category, as have most analyses of similar tombs from this period. We sought to test how adult age estimation methods compare in identifying young, middle, and old age individuals in commingled assemblages.

Materials and Methods We employed Transition Analysis 3 (TA3) and traditional …