Digital Commons Network^™

Molecular Mechanisms And Future Implications Of Vegf/Vegfr In Cancer Therapy, Sonia A Patel, Monique B Nilsson, Xiuning Le, Tina Cascone, Rakesh K Jain, John V Heymach

Faculty, Staff and Student Publications

Angiogenesis, the sprouting of new blood vessels from existing vessels, is one of six known mechanisms employed by solid tumors to recruit blood vessels necessary for their initiation, growth, and metastatic spread. The vascular network within the tumor facilitates the transport of nutrients, oxygen, and immune cells and is regulated by pro- and anti-angiogenic factors. Nearly four decades ago, VEGF was identified as a critical factor promoting vascular permeability and angiogenesis, followed by identification of VEGF family ligands and their receptors (VEGFR). Since then, over a dozen drugs targeting the VEGF/VEGFR pathway have been approved for approximately 20 solid tumor …

Balancing Renewable Energy And River Resources By Moving From Individual Assessments Of Hydropower Projects To Energy System Planning, Jeffrey J. Opperman, Juan Pablo Carvallo, Rafael Kelman, Rafael J. P. Schmitt, Rafael M. Almeida, Emily Chapin, Alexander Flecker, Marc Goichot, Guenther Guenther Grill, Julien J. Harou

School of Earth, Environmental, & Marine Sciences Faculty Publications

As governments and non-state actors strive to minimize global warming, a primary strategy is the decarbonization of power systems which will require a massive increase in renewable electricity generation. Leading energy agencies forecast a doubling of global hydropower capacity as part of that necessary expansion of renewables. While hydropower provides generally low-carbon generation and can integrate variable renewables, such as wind and solar, into electrical grids, hydropower dams are one of the primary reasons that only one-third of the world’s major rivers remain free-flowing. This loss of free-flowing rivers has contributed to dramatic declines of migratory fish and sediment delivery …

Inter-Seasonal Comparison Of Acoustic Propagation In A Thalassia Testudinum Seagrass Meadow In A Shallow Sub-Tropical Lagoon, Kevin M. Lee, Megan S. Ballard, Andrew R. Mcneese, Preston S. Wilson, Gabriel R. Venegas, Mathew C. Zeh, Abdullah Rahman

School of Earth, Environmental, & Marine Sciences Faculty Publications

Acoustic propagation measurements were collected in a seagrass meadow in a shallow lagoon for periods of over 65 h in winter and 93 h in summer. A bottom-deployed sound source transmitted chirps (0.1–100 kHz) every 10 min that were received on a four-receiver horizontal hydrophone array. Oceanographic probes measured various environmental parameters. Daytime broadband acoustic attenuation was 2.4 dB greater in summer than winter, and the median received acoustic energy levels were 8.4 dB lower in summer compared to winter. These differences were attributed in part to seasonal changes in photosynthesis bubble production and above-ground seagrass biomass.

Single-Cell Multi-Omics Integration For Unpaired Data By A Siamese Network With Graph-Based Contrastive Loss, Chaozhong Liu, Linhua Wang, Zhandong Liu

Faculty, Staff and Students Publications

BACKGROUND: Single-cell omics technology is rapidly developing to measure the epigenome, genome, and transcriptome across a range of cell types. However, it is still challenging to integrate omics data from different modalities. Here, we propose a variation of the Siamese neural network framework called MinNet, which is trained to integrate multi-omics data on the single-cell resolution by using graph-based contrastive loss.

RESULTS: By training the model and testing it on several benchmark datasets, we showed its accuracy and generalizability in integrating scRNA-seq with scATAC-seq, and scRNA-seq with epitope data. Further evaluation demonstrated our model's unique ability to remove the batch …

Notch Blockade Specifically In Bone Marrow-Derived Fsp-1-Positive Cells Ameliorates Renal Fibrosis, Yongdong Wu, Ming Liang, Fengzhang Huang, Owen H Cheng, Xiaoguang Xiao, Tae Hoon Lee, Luan Truong, Jizhong Cheng

Faculty, Staff and Students Publications

Background: The infiltration of inflammatory cells during a kidney injury stimulates myofibroblast activation leading to kidney fibrosis. Fibroblast-specific protein 1 (FSP-1) positive cells have been reported as either myofibroblasts or monocytes during tissue fibrosis. The functions of FSP-1+ cells that are associated with the development of renal fibrosis and the signaling pathways that regulate FSP-1+ cell activation have not been well defined. Methods: In mice with unilateral ureteral obstruction (UUO), we characterized FSP-1+ cells and determined the role of the Notch signaling pathway in the activation of bone marrow-derived FSP-1+ cells during kidney fibrosis. Results: In kidneys from mice with …

The Lysosomal Ragulator Complex Activates Nlrp3 Inflammasome In Vivo Via Hdac6, Kohei Tsujimoto, Tatsunori Jo, Daiki Nagira, Hachiro Konaka, Jeong Hoon Park, Shin-Ichiro Yoshimura, Akinori Ninomiya, Fuminori Sugihara, Takehiro Hirayama, Eri Itotagawa, Yusei Matsuzaki, Yuki Takaichi, Wataru Aoki, Shotaro Saita, Shuhei Nakamura, Andrea Ballabio, Shigeyuki Nada, Masato Okada, Hyota Takamatsu, Atsushi Kumanogoh

Duncan NRI Faculty and Staff Publications

The cellular activation of the NLRP3 inflammasome is spatiotemporally orchestrated by various organelles, but whether lysosomes contribute to this process remains unclear. Here, we show the vital role of the lysosomal membrane-tethered Ragulator complex in NLRP3 inflammasome activation. Deficiency of Lamtor1, an essential component of the Ragulator complex, abrogated NLRP3 inflammasome activation in murine macrophages and human monocytic cells. Myeloid-specific Lamtor1-deficient mice showed marked attenuation of NLRP3-associated inflammatory disease severity, including LPS-induced sepsis, alum-induced peritonitis, and monosodium urate (MSU)-induced arthritis. Mechanistically, Lamtor1 interacted with both NLRP3 and histone deacetylase 6 (HDAC6). HDAC6 enhances the interaction between Lamtor1 and NLRP3, resulting …

Feasibility And Preclinical Efficacy Of Cd7-Unedited Cd7 Car T Cells For T Cell Malignancies, Norihiro Watanabe, Feiyan Mo, Rong Zheng, Royce Ma, Vanesa C Bray, Dayenne G Van Leeuwen, Juntima Sritabal-Ramirez, Hongxiang Hu, Sha Wang, Birju Mehta, Madhuwanti Srinivasan, Lauren D Scherer, Huimin Zhang, Sachin G Thakkar, Laquisa C Hill, Helen E Heslop, Chonghui Cheng, Malcolm K Brenner, Maksim Mamonkin

Faculty, Staff and Students Publications

Chimeric antigen receptor (CAR)-mediated targeting of T lineage antigens for the therapy of blood malignancies is frequently complicated by self-targeting of CAR T cells or their excessive differentiation driven by constant CAR signaling. Expression of CARs targeting CD7, a pan-T cell antigen highly expressed in T cell malignancies and some myeloid leukemias, produces robust fratricide and often requires additional mitigation strategies, such as CD7 gene editing. In this study, we show fratricide of CD7 CAR T cells can be fully prevented using ibrutinib and dasatinib, the pharmacologic inhibitors of key CAR/CD3ζ signaling kinases. Supplementation with ibrutinib and dasatinib rescued the …

A Low-Fat/Sucrose Diet Rich In Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation, Prince K Akowuah, Carolina Lema, Rolando E Rumbaut, Alan R Burns

Faculty, Staff and Students Publications

High-fat/sucrose diet feeding in mice causes loss of corneal nerve function and impairs corneal wound healing. While changing to a diet with a low fat/sugar composition and enrichments in complex carbohydrates mitigates the reduction in nerve function, it remains to be determined if it has an effect on corneal wound healing. In this study, 6-week-old C57BL/6 male mice were fed either a normal diet or a high-fat/sucrose diet for 20 weeks. A third group (diet reversal) was placed on a high-fat/sucrose diet for 10 weeks followed by a normal diet for an additional 10 weeks. A central corneal epithelial abrasion …

Obesity Is Associated With Altered Tumor Metabolism In Metastatic Melanoma, Andrew W Hahn, Ashley V Menk, Dayana B Rivadeneira, Ryan C Augustin, Mingchu Xu, Jun Li, Xiaogang Wu, Aditya K Mishra, Tuba N Gide, Camelia Quek, Yan Zang, Christine N Spencer, Alexander M Menzies, Carrie R Daniel, Courtney W Hudgens, Theodore Nowicki, Lauren E Haydu, M A Wadud Khan, Vancheswaran Gopalakrishnan, Elizabeth M Burton, Jared Malke, Julie M Simon, Chantale Bernatchez, Nagireddy Putluri, Scott E Woodman, Y N Vashisht Gopal, Renato Guerrieri, Grant M Fischer, Jian Wang, Khalida M Wani, John F Thompson, Jeffrey E Lee, Patrick Hwu, Nadim Ajami, Jeffrey E Gershenwald, Georgina V Long, Richard A Scolyer, Michael T Tetzlaff, Alexander J Lazar, Dirk Schadendorf, Jennifer A Wargo, John M Kirkwood, Ralph J Deberardinis, Han Liang, Andrew Futreal, Jianhua Zhang, James S Wilmott, Weiyi Peng, Michael A Davies, Greg M Delgoffe, Yana G Najjar, Jennifer L Mcquade

Faculty, Staff and Student Publications

PURPOSE: Overweight/obese (OW/OB) patients with metastatic melanoma unexpectedly have improved outcomes with immune checkpoint inhibitors (ICI) and BRAF-targeted therapies. The mechanism(s) underlying this association remain unclear, thus we assessed the integrated molecular, metabolic, and immune profile of tumors, as well as gut microbiome features, for associations with patient body mass index (BMI).

EXPERIMENTAL DESIGN: Associations between BMI [normal (NL < 25) or OW/OB (BMI ≥ 25)] and tumor or microbiome characteristics were examined in specimens from 782 patients with metastatic melanoma across 7 cohorts. DNA associations were evaluated in The Cancer Genome Atlas cohort. RNA sequencing from 4 cohorts (n = 357) was batch corrected and gene set enrichment analysis (GSEA) by BMI category was performed. Metabolic profiling was conducted in a subset of patients (x = 36) by LC/MS, and in flow-sorted melanoma tumor cells (x = 37) and patient-derived melanoma cell lines (x = 17) using the Seahorse XF assay. Gut microbiome features were examined in an independent cohort (n = 371).

RESULTS: DNA mutations and copy number variations were not associated with BMI. GSEA demonstrated that tumors from OW/OB patients were metabolically quiescent, with downregulation of oxidative phosphorylation and multiple other metabolic pathways. Direct metabolite analysis and functional metabolic profiling confirmed decreased …

Global Gene Expression Analysis Reveals Complex Cuticle Organization Of The Tribolium Compound Eye, Qing Chen, Arun Kirshna Sasikala-Appukuttan, Zahabiya Husain, Anura Shrivastava, Marla Spain, Edward D Sendler, Bryce Daines, Stefan Fischer, Rui Chen, Tiffany A Cook, Markus Friedrich

Faculty, Staff and Students Publications

The red flour beetle Tribolium castaneum is a resource-rich model for genomic and developmental studies. To extend previous studies on Tribolium eye development, we produced transcriptomes for normal-eyed and eye-depleted heads of pupae and adults to identify differentially transcript-enriched (DE) genes in the visual system. Unexpectedly, cuticle-related genes were the largest functional class in the pupal compound eye DE gene population, indicating differential enrichment in three distinct cuticle components: clear lens facet cuticle, highly melanized cuticle of the ocular diaphragm, which surrounds the Tribolium compound eye for internal fortification, and newly identified facet margins of the tanned cuticle, possibly enhancing …

Perbandingan Bentuk Hukum Perusahaan Perseroan Negara Indonesia Dan Brunei Darussalam, Gilang Prabowo

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Limited Liability Company is a legal entity established under an agreement, carrying out business activities with authorized capital which is entirely divided into shares and fulfills the requirements stipulated in the law of limited liability companies and their implementing regulations. Research with a normative juridical approach that is descriptive begins with the regulation of limited liability companies, establishment, and organs contained in limited liability companies in Indonesia and comparison with the state of Brunei Darussalam. The purpose of this paper is to make Comparative Regulations governing the Indonesian state-owned companies with Brunei Darussalam.

Keywords: company; limited company; regulation; Indonesia; …

Food, Freedom, Fairness, And The Family Farm, Robin Rotman, Sophie Mendelson

West Virginia Law Review

The concept of the “family farm” holds powerful sway within the American narrative, embodying both nostalgia for an imagined past and anxiety for a future perceived to be under threat. Since the founding of the United States, this cultural ideal has been invoked in support of a rosy vision of agrarian democracy while obscuring the ways in which the U.S. Department of Agriculture’s codified definition of “family farm” has unfairly aggregated advantages for the benefit of a particular kind of family (nuclear) and farmer (white, male, straight). At the same time, consumers are misled by an under-interrogated conflation of family …

Uncovering The Role Of Cancer Associated Fibroblasts In Tumor Immunosuppression, Kamal Amirneni, Kavitha Yaddanapudi

Posters-at-the-Capitol

Current advances in cancer immunotherapy are hindered by the immunosuppressive nature of the tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) are a key component of the TME that contribute to suppressing the immune response. Chemokines and cytokines released by CAFs, such as IL-6, attract circulating monocytes which are converted into myeloid-derived suppressor cells (MDSCs). MDSCs suppress T-cells and natural killer cell proliferation which inactivates the immune response and deters immunotherapy. Both Prostaglandin E₂ (PGE₂) and granulocyte-macrophage colony-stimulating factor (GM-CSF) have been implicated in the CAF immunosuppressive pathway, but a causal link has yet to be established. We hypothesized …

Emotionally Unavailable: A Comparison On The Ability Of Children With Developmental Language Disorders To Interpret Emotions In Humans And Inanimate Objects, Savanna B. Gullett, Jade Robinson

Posters-at-the-Capitol

Developmental Language Disorder (DLD) is a neuro-developmental condition that emerges in early childhood and can persist into adulthood, manifesting as a variety of symptoms that can be significantly different in each individual. It has an estimated prevalence of 7.58% and is nearly 7 times more common in children than autism spectrum disorder (McGregor, 2020). As a population, individuals with DLD are at risk of facing significant issues in associating areas of language, including reading comprehension, problem-solving abilities, and social skills. Professionals have noticed emotional disconnect amongst individuals with DLD, leading to the proposition that those with DLD may have a …

Minute Pirate Bug And Big-Eyed Bug Populations In Pyramided Bt Sweet Corn Bordered By Native Perennial And Pasture Border Rows, Hanna Waller, John D. Sedlacek, Karen L. Friley, Jenny Galvin, Anjana Duwal

Posters-at-the-Capitol

Sweet corn is an important vegetable crop grown in Kentucky. The major sweet corn ear pests are European corn borer, Ostrinia nubilalis, and corn earworm, Helicoverpa zea. Ecological control measures have been introduced to manage these pests, reducing use of broad spectrum insecticides. Conservation biological control (CBC) is a component of these approaches. CBC manages pests in agroecosystems using habitat management to enhance populations of natural enemies that are already present in the system. Another important advancement is the cultivation of Bacillus thuringiensis (Bt) sweet corn resistant to the Lepidopteran corn ear pests. This study used CBC of corn ear …

A Dynamical System Model Of Dengue Transmission For Rio De Janeiro, Brazil, Gregory Schmidt, Benjamin Whipple, Vinodh Chellamuthu, Xiaoxia Xie

Spora: A Journal of Biomathematics

The dengue virus is a serious concern in many parts of the world, including Brazil. As data indicates, a prominent vector for dengue is the mosquito Aedes aegypti. By using the dengue incidence records from the Brazilian SINAN database, we estimate the population of A. aegypti within the city of Rio de Janeiro. Using historical climate data for Rio de Janeiro and the computed population estimates, we extend an existing model for the population dynamics of mosquitoes to incorporate precipitation in aquatic stages of development for A. aegypti.

Babel Blackness: The Aesth-Ethical Turn In Post-Colonial Translation, Emanuela Maltese

Living in Languages

“How do we make art in an ethical way?” (Marlene NourbeSe Philip) is the leading question lying at the basis of this article, which inspired by the story of the unauthorized Italian translation of Zong! seeks to investigate on the ethics of translation and propose a new turn in translation studies, namely a black aesth-ethical one. The proposal here examined is indeed informed by both aesthetics, and ethics. It presents translation as a practice, that draws on recent debates on black aesthetics, with specific reference to the Afro-optimism (AO) of cultural theorist and poet Fred Moten (2013, 2018, 2019) and …

Comparative Transcriptome Analysis Of Tolerant And Sensitive Genotypes Of Common Bean (Phaseolus Vulgaris L.) In Response To Terminal Drought Stress, Mayavan Subramani, Carlos Urrea, Rasheed Habib, Ketaki Bhide, Jyothi Thimmapuram, Venu Kalavacharla

Panhandle Research and Extension Center

We conducted a genome-wide transcriptomic analysis of three drought tolerant and sensitive genotypes of common bean to examine their transcriptional responses to terminal drought stress. We then conducted pairwise comparisons between the root and leaf transcriptomes from the resulting tissue based on combined transcriptomic data from the tolerant and sensitive genotypes. Our transcriptomic data revealed that 491 (6.4%) DEGs (differentially expressed genes) were upregulated in tolerant genotypes, whereas they were downregulated in sensitive genotypes; likewise, 396 (5.1%) DEGs upregulated in sensitive genotypes were downregulated in tolerant genotypes. Several transcription factors, heat shock proteins, and chaperones were identified in the study. …

Clinicopathologic Characteristics Of Early-Onset Breast Cancer: A Comparative Analysis Of Cases From Across Ghana, Patrick Kafui Akakpo, Emmanuel Gustav Imbeah, Lawrence Edusei, Simon Naporo, Kofi Ulzen-Appiah, Joe Nat Clegg-Lamptey, Florence Dedey, Josephine Nsaful, Nelson Affram, Beatrice Wiafe, Samuel Mensah, Michael Nortey, Mohammed Sheriff, Forster Amponsah-Manu, Kwabena Agbedinu, Evelyn M. Jiagge

Hematology/Oncology Articles

BACKGROUND: Breast cancer is the commonest cancer diagnosed globally and the second leading cause of cancer-related mortality among women younger than 40 years. This study comparatively reviewed the demographic, pathologic and molecular features of Early-Onset Breast Cancer (EOBC) reported in Ghana in relation to Late Onset Breast Cancer (LOBC).

METHODS: A descriptive, cross-sectional design was used, with purposive sampling of retrospective histopathology data from 2019 to 2021. Reports of core or incision biopsy, Wide Local Excision or Mastectomy with or without axillary lymph node dissection specimen and matched immunohistochemistry reports were merged into a single file and analysed with SPSS …

Jefferson Digital Commons Quarterly Report: October-December 2022, Anita Lai, Mlis

Jefferson Digital Commons Reports

This quarterly report includes:

• Articles
• Conferences and Symposiums
• Dissertations
• Faculty Books
• Grand Rounds and Lectures
• Interprofessional Story Slam
• JCRS Capstone Presentation
• Journals and Newsletters
• Miscellaneous
• Posters
• Scholarly Inquiry
• What People are Saying About the Jefferson Digital Commons

Subgenera Of Dacne Latreille, 1797 (Erotylidae: Erotylinae: Dacnini) Given Full Generic Rank, Paul E. Skelley

Insecta Mundi

Previously described subgenera of Dacne Latreille, 1797 (Coleoptera: Erotylidae) show charac­ter states and combinations implying closer relationships with genera other than with Dacne, suggesting “Dacne” is not monophyletic. These characters are briefly discussed along with the genera sharing the charac­ters. To improve the current classification, the subgenera of Dacne are raised to generic status as: Afrodacne Delkeskamp, 1954, Ameridacne Skelley, 2009, and Xenodacne Boyle, 1956. A checklist of all species included in these genera is presented, updating generic combinations as needed.

Clustering Climate And Management Practices To Define Environmental Challenges Affecting Gastrointestinal Parasitism In Katahdin Sheep, Brian C. Arisman, Joan M. Burke, James L. M. Morgan, Ronald M. Lewis

Department of Animal Science: Faculty Publications

Gastrointestinal nematodes (GIN) negatively affect the performance and well-being of sheep. Due to anthelmintic resistance, GIN are difficult to control leading producers to choose breeds that can exhibit resistance to parasitism. An example is Katahdin sheep. Katahdins are raised in various climates and management systems in the United States. These environmental factors can be combined to form eco-management groupings or clusters. We hypothesized that GIN challenge varies predictably based on the characteristics of these environmental clusters. Forty Katahdin producers from across the United States were surveyed for management information, with body weights (BW), fecal egg counts (FEC), and FAMACHA scores …

Ic 010 Gude To University Of Texas Graduate School Of Biomedical Sciences Records, 1970-, University Of Texas Graduate School Of Biomedical Sciences At Houston

Institutional Finding Aids

The University of Texas Graduate School of Biomedical Sciences records contain strategic plans, directories, policies manual, news, pictorial rosters, laboratory descriptions, Metabolism the Process of Life, catalogs, correspondence, What Goes On, annual reports. Quarterly progress reports, and dissertations. See more at IC 010.

System And Method Of Dynamic Light Source Control, Dennis Karl Killinger

USF Patents

A system and method of adjusting a field of view in an imaging system includes transmitting light across a transmission optical path and defining a field of view encompassing both uniform and spatially tenuous target objects within the transmitted light. A sensor within a return optical path of reflected light from at least a portion of one of the target objects allows a data processing computer to compile an image from a series of data outputs from the sensor. The image is analyzed to determine a region of interest within the image and by dynamically adjusting the light source, the …

Exploring Associations Between Military Identity And Well-Being Outcomes Among Post-9/11 Veterans After Separation, James David Lee

Dissertations and Theses

Approximately 200,000 service members exit the military each year; as of 2016, there were 19 million veterans in the U.S. As service members transition out of the military and acclimate to civilian life, they face a multitude of stressors. For example, estimates vary from 44 to 72% of veterans reportedly experience increased stress during their transition which often entails securing civilian employment, navigating interpersonal difficulties, and adapting to the challenges of civilian life. These stressors have harmful consequences and have been linked to physical and mental health, and suicide risk. Despite these findings, research examining the well-being of veterans following …

Wild Cards In Natural Resource Planning: High Impact Surprises That Shape The Future, Dr. David Bengston

Natural Resources Journal

Wild cards are improbable, high impact events. Such events, like the COVID-19 pandemic, have the ability to shape policy by upending entire systems and paradigms. Unfortunately, long-term planning and policymaking rarely account for wild card events. Instead, planning and policymaking typically assume that existing trends will continue without major disruption. Moreover, adequately planning for potential wild card events is challenging because they are inherently difficult to predict. However, planning for wild card events in natural resources and environmental policymaking is vital as global developments, such as climate change, create more extreme conditions and challenges. This review, (1) defines and characterizes …

Phytoecdysteroids And Anabolic Effect Of Atriplex Dimorphostegia: Uplc-Pda-Ms/Ms Profiling, In Silico And In Vivo Models, Noha Swilam, German University In Cairo (Guc), Singab, The British University In Egypt (Bue), Iriny M. Ayoub

Pharmacy

Atriplex dimorphostegia (Saltbush) is an annual halophytic shrub that is widely distributed across various parts of Asia. The current study is the first to report the metabolites profile of the total ethanol extract of the aerial parts of A. dimorphostegia (TEAD), and its anabolic activity together with the isolated 20-hydroxyecdysone (20-HE) in orchiectomized male rats. TEAD was analyzed and standardized utilizing UPLC-PDA-ESI–MS/MS and UPLC-PDA-UV techniques, resulting in tentative identification of fifty compounds including polyphenols, steroids and triterpenoids. In addition, 20-HE was quantified, representing 26.79 µg/mg of the extract. Phytochemical investigation of TEAD resulted in the isolation of 20-HE from the …

Radiation Therapy For Retroperitoneal Sarcomas: A Strass-Ful Situation, Ahsan S Farooqi, B Ashleigh Guadagnolo, Devarati Mitra, Andrew J Bishop

Faculty, Staff and Student Publications

Locoregional recurrence (LRR) is the predominant pattern of relapse and often the cause of death in patients with retroperitoneal sarcomas (RPS). As a result, reducing LRR is a critical objective for RPS patients. However, unlike soft tissue sarcomas (STS) of the superficial trunk and extremity where the benefits of radiation therapy (RT) are well-established, the role of RT in the retroperitoneum remains controversial. Historically, preoperative or postoperative RT, either alone or in combination with intraoperative radiation (IORT), was commonly justified for RPS based on extrapolation from the superficial trunk and extremity STS literature. However, long-awaited results were recently published from …

Intouch Week Of January 3, 2023, New York Medical College

InTouch

• NYMC Takes a Look Back at 2022
• Public Health Program Receives Seven-Year CEPH Accreditation
• Diversity in Research Study Group Inspires Student Research Collaborations Across a Variety of Topics
• NYMC Examines Virtual Interviews for Residencies Due to COVID-19 Travel Restrictions

Auto–Transition In Radg Based On Chaotic System, Laith M. Kadhum, Ahmad Firdaus, Mohamad Fadli Bin Zolkipli, Syifak Izhar Hisham, Luhur Bayuaji, Mohd Faizal Ab Razak

Iraqi Journal for Computer Science and Mathematics

The RADG (Reaction Automata Direct Graph) cryptosystem is the automata direct graph and reaction states combination. The classical RADG does not require key exchange (keyless), or agreement between users just the design of RADG, which is static. The RADG algorithm with keys has two agreements between users, one is on the keys, and other is a design of RADG. The RADG design depends on states and transitions between them, since transitions between states are static transitions, or dynamic transitions have agreement between users to determine the type of state (Jump state, Reaction state) of RADG algorithm with keys, and the …