Digital Commons Network^™

The Sflt-1/Plgf Ratio In Pregnant Patients Affected By Covid-19, Katarzyna Kosinska-Kaczynska, Ewa Malicka, Iwona Szymusik, Norbert Dera, Michal Pruc, Stepan Feduniw, Zubaid Rafique, Lukasz Szarpak

Faculty, Staff and Students Publications

COVID-19 in pregnant women increases the risk of adverse pregnancy outcomes, including preeclampsia. This meta-analysis aimed to examine the effect of SARS-CoV-2 infection on sFlt-1/PIGF ratio during pregnancy. The study was designed as a systematic review and meta-analysis. PubMed, Web of Science, Embase and Cochrane Library were searched for relevant studies reporting the sFlt-1/PlGF ratio in pregnant women with COVID-19. Results were compared using meta-analysis by the Mantel-Haenszel method. A total of 7 studies were included in the analysis. sFlt-1/PlGF ratios between COVID-19 positive vs. negative women were 45.8 ± 50.3 vs. 37.4 ± 22.5, respectively (SMD = 1.76; 95% …

Impact Of Kindergarten Transition Practices In Promoting Positive Behavioral School Readiness Skills, Tyler M. Szydlo, Elyse M. Farnsworth

Perspectives on Early Childhood Psychology and Education

Successfully adjusting to the behavioral demands of kindergarten is a pivotal, yet challenging, developmental milestone for students, making it imperative that schools have a comprehensive menu of universal transition practices and targeted transition interventions available. This systematic review was conducted to synthesize and evaluate the existing research on the outcomes associated with universal transition practices and targeted transition interventions aimed at improving social-emotional behavioral skills important to the transition to kindergarten. 17 studies were identified that met the inclusion criteria. Results from this review highlight the utility of targeting self-regulation skills in students transitioning to kindergarten through multi-component interventions that …

The Pod Generation, Dereck Daschke

Journal of Religion & Film

This is a film review of The Pod Generation (2023), directed by Sophie Barthes.

Non-Aggressive Competition Between Males Of Srilankametrus Yaleensis (Kovařík Et Al., 2019) (Scorpionidae), And Other Types Of Agonistic Behavior Observed In Scorpions, Victoria Tang

Euscorpius

A peculiar intraspecific agonistic behavior involving a non-aggressive physical combat is reported between the adult males of Srilankametrus yaleensis (Kovařík et al., 2019) (Scorpionidae: Heterometrinae). The adult males were observed to resort to a ritualized and relatively gentle way for strength demonstration. The combat is characterized by lateral spreading of pedipalps, chelicerae-to-chelicerae collision, and entanglement of metasomal segments. This behavior is hereby considered a form of an intrasexual combat defined as the “arm-span competition”. It is hypothesized to be beneficial for solving territorial and/ or sexual competitions while avoiding unnecessary mortality which could pose adverse impact to the natural populations. …

Authentic And Unapologetic: Culturally Responsive Leadership Strategies Used By California Community College Senior-Level Leaders Of Color, Renee Craig-Marius

Dissertations

Purpose: The purpose of this qualitative study was to identify and describe how California Community College senior-level leaders of color are culturally responsive in their leadership strategies, based on Horsford, Grosland, and Gunn’s (2011) culturally relevant leadership framework.

Methodology: This qualitative ethnographic study identified and described the culturally responsive leadership practices utilized by 15 senior-level leaders of color within California Community Colleges and explored how their lived experiences and identities influence their ability to lead their institutions using the four dimensions of Horsford et al.’s (2011) culturally relevant leadership framework: political context, personal journey, pedagogical approach, and professional duty. …

Brivaracetam To Treat Partial Onset Seizures In Adults., Dustin Latimer, David Le, Evan P. Falgoust, Patrick Ingraffia, Alaa Abd-Elsayed, Elyse M. Cornett, Rupin Singh, Joohee Choi, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

School of Pharmacy Faculty Articles

PURPOSE OF REVIEW: Seizures are a hyperexcitable, and hypersynchronous imbalance between excitatory and inhibitory factors (E/I imbalance) in neurotransmission, and epilepsy is the recurrent manifestation of seizures within a reasonable time frame and without being attributable to a reversible cause. Brivaracetam is a derivative of the antiepileptic agent, levetiracetam, that is used as adjuvant therapy for focal onset seizures. It was approved by the FDA in 2016 and has shown promising results with minimal adverse effect reactions in clinical trials.

RECENT FINDINGS: Brivaracetam has been used in multiple clinical trials at various dosages in adults that have partial-onset seizures refractory …

Suvorexant, A Novel Dual Orexin Receptor Antagonist, For The Management Of Insomnia., Andrew H. Han, Carolin R. Burroughs, Evan P. Falgoust, Jamal Hasoon, Grace Hunt, Juyeon Kakazu, Tim Lee, Adam M. Kaye, Alan D. Kaye, Latha Ganti

School of Pharmacy Faculty Articles

PURPOSE OF REVIEW: The present investigation is a comprehensive review regarding the use of Suvorexant for insomnia treatment. It covers the background, pathophysiology, and significance of addressing insomnia, the pharmaceutical details of Suvorexant, and its safety, efficacy, and implications in treating insomnia. We further discuss Suvorexant's role in targeting insomnia with other comorbidities.

RECENT FINDINGS: Insomnia refers to poor quality and/or quantity of sleep. While there are many existing treatments such as benzodiazepines, melatonin agonists, TCAs, and atypical antipsychotics used to target various receptors involved in normal induction and maintenance of sleep, Suvorexant is an antagonist that specifically targets orexin …

Race And Gender In Ophthalmology: A National Analysis Of Medical Students With Intention To Pursue The Field, John Chhoa, John Jawiche, Priya A. Uppal, Thilaka Arunachalam, Mytien Nguyen, Branden Eggan, Hyacinth Mason, Jacqueline Busingye

Journal of Academic Ophthalmology

Abstract

Purpose The field of ophthalmology must become more reflective of the increasingly diverse U.S. population. This study characterizes students intending to pursue ophthalmology and practice in an underserved area versus other surgical and nonsurgical fields.

Subjects Deidentified responses from 92,080 U.S. MD students who matriculated in the academic years beginning from 2007 to 2011 were obtained from the Association of American Medical Colleges (AAMC) Graduation Questionnaires.

Methods Study participants were those who fully completed the AAMC Graduation Questionnaire. Chi-squared and multivariate logistical regressions were used for analyses.

Results Ophthalmology intending graduates (OIG; n = 1,177) compared with other surgical …

Individual And Combined Antioxidant Activity Of Spices And Spice Phenolics, Mohammad B Hossain, Lubna Ahmed, Anna Belen Martin-Diana, Nigel P Brunton, Catherine Barry-Ryan

Faculty, Staff and Student Publications

The present study investigated the interaction effects (additive, synergistic, and antagonistic) of different groups of spices, their constituent phenolic compounds, and synthetic antioxidants on the total phenol (TP) content and antioxidant activity, as measured by the ferric-reducing antioxidant power (FRAP) of the mixtures. The results showed that there was an additive effect in all the groups studied, except for the group containing turmeric or curcumin. The groups containing turmeric or curcumin showed a moderate synergistic effect. Among the groups of spices, the highest summated TP (50.6 mg GAE/mL) and FRAP (106.2 mg Trolox/mL) values were observed in the group containing …

Review Of Interventional Therapies For Refractory Pediatric Migraine., Jacquelin Peck, Justin Zeien, Megha Patel, Elyse M. Cornett, Amnon A. Berger, Jamal Hasoon, Hisham Kassem, Jai Won Jung, Giovanni F. Ramírez, Paola Fugueroa, Neil R. Singhal, Jaehong Song, Adam M. Kaye, Alan D. Kaye, Sarang S. Koushik, Natalie H. Strand, Latha Ganti

School of Pharmacy Faculty Articles

This is a review of the latest and seminal evidence in pediatric migraine. It covers the etiology and pathophysiology known today, and then will review treatment options, efficacy and safety, quality of data and indications. Though migraine is usually regarded as an infliction in adults, it is not uncommon in the pediatric population and affects up to 8% of children. Children may experience migraine differently than adults, and present not only with headache but also frequent gastrointestinal symptoms. They are frequently shorter in duration than in adults. Traditional migraine treatment in adults is less effective in children. In this population, …

Supplementation Of Sulfide Or Acetate And 2-Mercaptoethane Sulfonate Restores Growth Of The Methanosarcina Acetivorans Δhdrabc Deletion Mutant During Methylotrophic Methanogenesis, Alicia M. Salvi, Niaz Bahar Chowdhury, Rajib Saha, Nicole R. Buan

Department of Biochemistry: Faculty Publications

Methanogenic archaea are important organisms in the global carbon cycle that grow by producing methane gas. Methanosarcina acetivorans is a methanogenic archaeum that can grow using methylated compounds, carbon monoxide, or acetate and produces renewable methane as a byproduct. However, there is limited knowledge of how combinations of substrates may affect metabolic fluxes in methanogens. Previous studies have shown that heterodisulfide reductase, the terminal oxidase in the electron transport system, is an essential enzyme in all methanogens. Deletion of genes encoding the nonessential methylotrophic heterodisulfide reductase enzyme (HdrABC) results in slower growth rate but increased metabolic efficiency. We hypothesized that …

Glycolysis Regulates Kras Plasma Membrane Localization And Function Through Defined Glycosphingolipids, Junchen Liu, Ransome Van Der Hoeven, Walaa E Kattan, Jeffrey T Chang, Dina Montufar-Solis, Wei Chen, Maurice Wong, Yong Zhou, Carlito B Lebrilla, John F Hancock

Faculty, Staff and Student Publications

Oncogenic KRAS expression generates a metabolic dependency on aerobic glycolysis, known as the Warburg effect. We report an effect of increased glycolytic flux that feeds into glycosphingolipid biosynthesis and is directly linked to KRAS oncogenic function. High resolution imaging and genetic approaches show that a defined subset of outer leaflet glycosphingolipids, including GM3 and SM4, is required to maintain KRAS plasma membrane localization, with GM3 engaging in cross-bilayer coupling to maintain inner leaflet phosphatidylserine content. Thus, glycolysis is critical for KRAS plasma membrane localization and nanoscale spatial organization. Reciprocally oncogenic KRAS selectively upregulates cellular content of these same glycosphingolipids, whose …

Pharmacognostical And Phytochemical Evaluation Of A Unani Polyherbal Formulation: Dawa Ul Kurkum By Hptlc, Meenakshi Gupta, Sajida Sumaiya, Sher Ali, Tanveer Naved, Archana Sharma, Ajaz Ahmad, Mohammed Sikander, Maryam Sarwat

School of Medicine Publications

Background: Dawa ul Kurkum (Duk) is a widely used Unani formulation. It consists of seven plant herbs, including stigmas of Crocus sativus L., rhizomes of Nardostachys jatamansi (D.Don) DC., the bark of Cinnamomum cassia (L.) J. Presl., shoot of Cymbopogon jwarancusa (Jones ex Roxb.) Schult., the resin of Commiphora wightii (Arn.) Bhandari, roots of Saussurea lappa (Decne.) Sch.Bip., and bark of Cinnamomum zeylanicum Blume. However, no study has been previously conducted to characterize this formulation. Thus, the present study was designed to carry out the pharmacognostic and phytochemical characterization of Duk. Methods: Duk was prepared following the protocols in Bayaz …

Non-Equilibrium Colloidal Phenomena In Magnetic Fields And Photoillumination: From Controlling Living Microbots To Understanding Microplastics, Ahmed Al Harraq

LSU Doctoral Dissertations

Colloids are a ubiquitous class of materials composed of microscopic particles suspended in a continuous phase which are found in everyday products and in nature. Colloids are also useful models for studying the spontaneous arrangement of matter from individual building blocks to mesophases. Standard treatment of colloid science is based on the assumption of equilibrium conditions, as defined in traditional thermodynamics. However, novel assembly mechanisms and motility are unlocked by pushing colloids away from equilibrium using external energy. In addition, many colloids in nature and in industrial applications exchange energy and mass with the surrounding environment thus behaving in a …

Control Of Cultural And Bodily Reproduction: The Denial Of Autonomy In The United States, Peru And Globally, Anna M. Schloerb

Tapestries: Interwoven voices of local and global identities

Statement of Purpose:

This project seeks to look at the ways the state and hegemonic devices of power control cultural and bodily reproduction. It asks the question of how this control inhibits people's reproductive autonomy, cultural identity, language, and generational knowledge transmission. I offer specific examples of how this control has functioned in the US, with immigrants, Indigenous, Black people and other marginalized groups. My grandmother is from Lima, Peru and because of that connection, and the inspiration of this piece, I wanted to use the 1990s-2000s Sterilization in Peru as a case study of hegemonic control happening more globally. …

Abolish The Body Mass Index: A Historical And Current Analysis Of The Traumatizing Nature Of The Bmi, Franny M. Redpath

Tapestries: Interwoven voices of local and global identities

Statement of Purpose

Rage, change, and liberation; these are the concepts that our papers, collectively, embody. I was enraged. I am enraged. But even through the rage, I am choosing to center this paper around enacting change. Throughout maturation, I have increasingly been deeply affected by how the United States medical system and insurance industry treats patients with a Body Mass Index of over 30, as a young fem person whose doctors deny validity and respect. I have been sent the message that my body is not worthy of the same treatment that is afforded to other, smaller, patients. I …

Challenging Medical Authority: Autonomous Health Movement And Contemporary Harm Reduction Practices In Minneapolis, Louise D. Bequeaith

Tapestries: Interwoven voices of local and global identities

Statement of Purpose: Sometimes, I find it difficult to comprehend the vast problems and systems of inequity that exist within the United States’ (US) healthcare system. The US’s profit-driven model of health is so deeply integrated into our society that it feels impossible to change. It is hard to imagine an alternative. The COVID-19 pandemic has created an environment where the health of our communities is brought to the forefront. It is a moment when as a society we are beginning to understand that health crises are not a sum of individual failures, but instead are systematically produced and reproduced …

Novel Derivative For Dithiocarbamite Containing A New Sulphur-Azo Linkage And Its Complexes With Sn(Ii), Sn(Iv), Co(Ii), Ni(Ii) And Cu(Ii) Ions; Synthesis, Characterization And Antibacterial Activity, Wissam Abbas Ali, Hayder Hamied Mihsen, Sajid H. Guzar

Al-Bahir

The new ligand N-methyl-N-((((4-nitrophenyl)diazenyl)thio) carbonothioyl) aniline (LS2) was prepared by the reaction of 4-nitrobenzenediazonium salts with a (sodium N-methyl- N-phenyldithiocarbamate), a new ligand containing azo-sulphur linkage. A series of metal ions Sn(II), Sn(IV), Co(II), Ni(II), and Cu(II) were used to prepare metal complexes through reaction of two moles of LS2 ligand with one mole of appropriate metal chloride. The prepared compounds were characterized by CHNS elemental analysis, infrared spectroscopy (FT-IR), 1H NMR-spectroscopy, mass spectroscopy, UV-visible spectroscopy, magnetic susceptibility, and conductivity measurements. Stoichiometry was determined using analytical and spectroscopic information and it was found to be 1:2 (metal to a ligand) …

Créativité Assistée Par Ordinateur : Composer La Musique D'Un Film En Utilisant Uniquement Sa Courbe De Luminosité Extraite Automatiquement, Felipe Ariani, Marcelo Caetano, Javier Elipe Gimeno, Ivan Magrin-Chagnolleau

Presidential Fellows Articles and Research

Dès sa conception, l'ordinateur a trouvé des applications pour accompagner la créativité des humains. De nos jours, le débat sur les ordinateurs et la créativité implique plusieurs défis, tels que comprendre la créativité humaine, modéliser le processus créatif, et programmer l'ordinateur pour qu'il présente un comportement qui semble être créatif dans une certaine mesure. Dans cet article, nous nous intéressons à la manière dont l'ordinateur peut être utilisé comme un outil favorisant la créativité dans une composition musicale. Nous avons extrait automatiquement la courbe de luminosité d'un film muet et l'avons ensuite utilisée pour composer une pièce musicale pour accompagner …

Additional Curricular Changes Proposed For 2023-2025 Morris Catalog Pt. 2, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Faculty Senate Agenda, February 6, 2023, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Call to Order
  • Approval of Minutes
• University Business
• Faculty Senate Presidency Business
• Information
  • Educational Policies Committee
  • Export Control Policy
  • Policy 369 – Other Leave
• Reports
  • Professional Responsibilities & Procedures Committee Annual Report
  • Office of Research Annual Report
  • School of Graduate Studies Annual Report
  • Faculty Diversity, Development & Equity Annual Report
  • Faculty Composition AY 2021
• Old Business
• New Business
  • Committee to Investigate Divestment
  • Amend Agenda to include Faculty Senate President Reports
• Adjourn

Centering Culture In The Treatment Of Opioid Use Disorder With American Indian And Alaska Native Communities: Contributions From A National Collaborative Board, Katherine A. Hirchack, Melanie Nadeau, Angel Vasquez, Alexandra Hernandez-Vallant, Kyle Smith, Cuong Pham, Karen Anderson Oliver, Paulette Baukol, Karen Lizzy, Raquel Shaffer, Jalene Herron, Aimee M. C. Campbell, Kamilla L. Venner

Indigenous Health Faculty Publications

American Indian/Alaska Native (AI/AN) communities are disproportionally impacted by the opioid overdose epidemic. There remains a dearth of research evaluating methods for effectively implementing treatments for opioid use disorder (OUD) within these communities. We describe proceedings from a 2-day Collaborative Board (CB) meeting tasked with developing an implementation intervention for AI/AN clinical programs to improve the delivery of medications to treat OUD (MOUD). The CB was comprised of Elders, cultural leaders, providers, individuals with lived experience with OUD, and researchers from over 25 communities, organizations, and academic institutions. Conversations were audio-recorded, transcribed, and coded by two academic researchers with interpretation …

Leading Change: Generating Cultural Responsiveness And Competence In Nursing, Kerstin G. Hudgins

Dissertations

Culturally responsive teachings prepare students to support social justice, diversity, equity, and inclusion (DEI) in and beyond the classroom. Rising reports of culturally insensitive care and the reported challenges that nurses experience when caring for culturally diverse patients warrant the advancement of the intercultural readiness of nursing students. The study investigated the cultural content taught, encompassing LGBTQ+ health education, at the School of Nursing at a historically black college and university (HBCU) in the Southeastern United States. The participant selection involved purposeful sampling of various stakeholders engaged in interviews and focus groups, including faculty, nursing students, and nurse managers with …

The Visualization Of Orphadata Neurology Phenotypes, Daniel B. Hier, Raghu Yelugam, Michael D. Carrithers, Donald C. Wunsch

Electrical and Computer Engineering Faculty Research & Creative Works

Disease Phenotypes Are Characterized by Signs (What a Physician Observes during the Examination of a Patient) and Symptoms (The Complaints of a Patient to a Physician). Large Repositories of Disease Phenotypes Are Accessible through the Online Mendelian Inheritance of Man, Human Phenotype Ontology, and Orpha data Initiatives. Many of the Diseases in These Datasets Are Neurologic. for Each Repository, the Phenotype of Neurologic Disease is Represented as a List of Concepts of Variable Length Where the Concepts Are Selected from a Restricted Ontology. Visualizations of These Concept Lists Are Not Provided. We Address This Limitation by using Subsumption to Reduce …

Hunting Behavior Of A Solitary Sailfish Istiophorus Platypterus And Estimated Energy Gain After Prey Capture, Ryan K. Logan, Sarah M. Luongo, Jeremy Vaudo, Bradley M. Wetherbee, Mahmood Shivji

Biology Faculty Articles

Foraging behavior and interaction with prey is an integral component of the ecological niche of predators but is inherently difficult to observe for highly mobile animals in the marine environment. Billfishes have been described as energy speculators, expending a large amount of energy foraging, expecting to offset high costs with periodic high energetic gain. Surface-based group feeding of sailfish, Istiophorus platypterus, is commonly observed, yet sailfish are believed to be largely solitary roaming predators with high metabolic requirements, suggesting that individual foraging also represents a major component of predator–prey interactions. Here, we use biologging data and video to examine daily …

The Diamond, January 27, 2023, Dordt University

Dordt Diamond

• Front Page: Remembering Emma Nibbelink; Progress Through Collaboration; East Campus Apartments to Get New Appliances
• News: Increased Vandalism Prompts Mandatory Meeting; Goodbye Twosdays; Howard Wilson Retires
• Feature: Swimming into the Future; Winter Storms Impact
• Opinion: America's Health Literacy Crisis; Conservatives on Campus Need Coordination
• Art & Entertainment: The 13-Year Sequel - Avatar: The Way of Water Film Review; Puss in Boots: The Last Wish; Beloved Video Game "The Last of Us" Turned into Live-Action TV; The Art of War; First High School Art Exhibit to Begin March 1st; New Sports Broadcasting Class …

4d Lung Mri With High-Isotropic-Resolution Using Half-Spoke (Ute) And Full-Spoke 3d Radial Acquisition And Temporal Compressed Sensing Reconstruction, Can Wu, Guruprasad Krishnamoorthy, Victoria Yu, Ergys Subashi, Andreas Rimner, Ricardo Otazo

Faculty, Staff and Student Publications

Objective:

To develop a respiratory motion-resolved 4D MRI technique with high-isotropic-resolution (1.1 mm) using 3D radial sampling, camera-based respiratory motion sensing, and temporal compressed sensing reconstruction for lung cancer imaging.

Approach:

Free-breathing half- and full-spoke 3D golden-angle radial acquisitions were performed on eight healthy volunteers and eight patients with lung tumors of varying size. A back-and-forth k-space ordering between consecutive interleaves of the 3D radial acquisition was performed to minimize eddy current-related artifacts. Data were sorted into respiratory motion states using camera-based motion navigation and 4D images were reconstructed using temporal compressed sensing to reduce scan time. Normalized sharpness indices …

A New Mechanism For Glymphatic Flow Of Interstitial Fluid In Branched Perivascular Spaces Of The Brain, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

Objective. To explore the biophysics of interstitial tissue fluid flow in the brain, based upon the anatomy and mechanics of the perivascular spaces, in order to better understand how glymphatic flow happens. Methods. The dynamics of fluid flow at cardiac frequencies are investigated in rapidly computable, branched, geometric models of brain tissue at multiple scales. The models are supplied by intermingled trees of penetrating arteries and veins. They include pulsatile changes in intracranial pressure and intravascular pressure, elastic expansion of brain tissue, and nonlinear changes in resistance to flow of cerebrospinal fluid along the axis of the Virchow-Robin space. Resulting …

Regenerative Agriculture - A Literature Review On The Practices And Mechanisms Used To Improve Soil Health, Ravjit Khangura, David Ferris, Cameron Wagg, Jamie Bowyer

Natural Resources Research Articles

Conventional farming practices can lead to soil degradation and a decline in productivity. Regenerative agriculture (RA) is purported by advocates as a solution to these issues that focuses on soil health and carbon sequestration. The fundamental principles of RA are to keep the soil covered, minimise soil disturbance, preserve living roots in the soil year round, increase species diversity, integrate livestock, and limit or eliminate the use of synthetic compounds (such as herbicides and fertilisers). The overall objectives are to rejuvenate the soil and land and provide environmental, economic, and social benefits to the wider community. Despite the purported benefits …

Displaying And Delivering Viral Membrane Antigens Via Ww Domain–Activated Extracellular Vesicles, Sengjin Choi, Zhiping Yang, Qiyu Wang, Zhi Qiao, Maoyun Sun, Joshua Wiggins, Shi-Hua Xiang, Quan Lu

Nebraska Center for Virology: Faculty Publications

Membrane proteins expressed on the surface of enveloped viruses are conformational antigens readily recognized by B cells of the immune system. An effective vaccine would require the synthesis and delivery of these native conformational antigens in lipid membranes that preserve specific epitope structures. We have created an extracellular vesicle–based technology that allows viral membrane antigens to be selectively recruited onto the surface of WW domain–activated extracellular vesicles (WAEVs). Budding of WAEVs requires secretory carrier-associated membrane protein 3, which through its proline-proline-alanine-tyrosine motif interacts with WW domains to recruit fused viral membrane antigens onto WAEVs. Immunization with influenza and HIV viral …