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2023

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Dietary Histidine: Broiler Responsiveness With And Without Endogenous Histidine Reserve Consideration, Kenneth Blake Nelson Aug 2023

Dietary Histidine: Broiler Responsiveness With And Without Endogenous Histidine Reserve Consideration, Kenneth Blake Nelson

Graduate Theses and Dissertations

In the past, histidine warranted little concern from poultry nutritionists because it was seldom deficient in practical broiler diets. With most essential amino acids now commercially available as feed-grade forms to partially replace intact protein ingredients, histidine and its minimum in least-cost formulation are receiving fresh attention. Published histidine requirement data for broilers are sparce, and many of these studies have been conducted on males within the first three weeks post-hatch. Moreover, rudimentary dose-response experimental designs may not be applicable to estimate histidine requirements in later growth periods because histidine is uniquely stored within the body. In times of dietary …


Nutrient Responses To Hippuric Acid In Sheep Urine Applied To Pasture Soil Cores, Ethan Avery Collins Aug 2023

Nutrient Responses To Hippuric Acid In Sheep Urine Applied To Pasture Soil Cores, Ethan Avery Collins

Graduate Theses and Dissertations

Hippuric acid is a breakdown product of tannins, which bind with proteins in the animal rumen and slow down protein metabolism, thus increasing nitrogen (N) retention in the animal. Increased hippuric acid concentration in bovine and ovine urine applied to soil may decrease rates of nitrification, denitrification, and nitrous oxide fluxes in pasture soils. Additionally, condensed tannins have increased rates of carbon mineralization when incorporated in humus and leaf litter. To evaluate effects of hippuric acid concentration, treatments of urine from sheep fed a tannin-supplemented diet, synthetic urine, or urea controls were applied to intact soil cores seeded with crabgrass …


Beef And Dairy Substitution Effects Associated With Carbon Labeling And An Information Intervention, Sara Gardner Hedgecock Aug 2023

Beef And Dairy Substitution Effects Associated With Carbon Labeling And An Information Intervention, Sara Gardner Hedgecock

Graduate Theses and Dissertations

Understanding consumer perceptions of carbon emissions in agriculture is a critical step to help increase the sustainability of food consumption. According to the Food and Agriculture Organization of the United Nations, 14.5 percent of all global anthropogenic GHG emissions are estimated to be represented by livestock (FAO), and cattle, raised for beef and milk, are the largest animal species responsible for emissions, comprising over 60 percent of the livestock sector’s emissions. This motivates this study’s analysis of beef and dairy milk products and alternatives. To better understand how consumers may substitute meat and milk products when provided with information about …


Securing Rice Safety Through Innovative Radiative Heat Treatment And Proper Storage, Faith Achieng Ouma Aug 2023

Securing Rice Safety Through Innovative Radiative Heat Treatment And Proper Storage, Faith Achieng Ouma

Graduate Theses and Dissertations

Securing the microbial safety of rice is a rising priority within the food industry, especially when used as an ingredient to manufacture ready-to-eat, minimally-processed products. Mold contamination is typically the most problematic for rice because certain species of Aspergillus produce toxic secondary metabolites known as aflatoxins, rendering the grain unfit for human and animal consumption. The objectives of this study are to: (1) investigate the effectiveness of using high-power (915 MHz frequency), short-duration microwaves (MWs) to inactivate microbes on rough rice; (2) use a three-level screening design to determine which storage factors, such as temperature, relative humidity (RH), storage duration, …


Runoff Water Quality And Crop Growth As Affected By Wastewater-Derived Struvite, Machaela Morrison Aug 2023

Runoff Water Quality And Crop Growth As Affected By Wastewater-Derived Struvite, Machaela Morrison

Graduate Theses and Dissertations

Mined phosphate rock, used to produce phosphorus (P) fertilizers, is a finite resource. Struvite (MgNH4PO4 • 6H2O) that has been synthetically produced from a stock solution of known P and nitrogen (N) concentrations has been shown to be an effective, alternative fertilizer-P source for various crops. However, little is known about the runoff-water-quality implications from and the crop response to soil application of struvite created from an actual municipal wastewater source. This study consisted of two objectives: i) to evaluate the effects of soil [i.e., Creldon (Oxyaquic Fragiudalf), Dapue (Fluventic Hapludoll), Roxana (Typic Udifluvent), and Calloway (Aquic Fraglossudalf) series], fertilizer-P …


Modeling The Egyptian Goose (Alopochen Aegyptiaca) Invasion; And Future Concerns, Percival Matzinger Marshall Aug 2023

Modeling The Egyptian Goose (Alopochen Aegyptiaca) Invasion; And Future Concerns, Percival Matzinger Marshall

Graduate Theses and Dissertations

In an increasingly interconnected world, the ecological and financial cost of invasive species is expected to continue to climb through the movement of exotic biota. Understanding the driving forces behind how a species invades, what environments promote their establishment, and what impacts they are likely to have on the invaded environment are all critical for management. Waterfowl, order Anseriformes, are one such category of invasive species of concern due to their popularity of accidental introduction, ease of movement, and propensity to affect both terrestrial and aquatic ecosystems. The Egyptian Goose (Alopochen aegyptiaca) is a native to the African continent that …


Non-Energy Circular Economy Potential Of Rice Husks: A Techno-Eco-Environmental Assessment, Winfred Oppong Yeboah Aug 2023

Non-Energy Circular Economy Potential Of Rice Husks: A Techno-Eco-Environmental Assessment, Winfred Oppong Yeboah

Graduate Theses and Dissertations

The non-energy circular bioeconomy potential of rice husks was examined via sustainability assessments, namely life cycle assessment (LCA), life cycle impact cost assessment (LCICA), and techno-economic assessment (TEA). The study was conducted with three objectives. The first objective was to review previous studies on the non-energy utilization potential of rice husks by the method of meta-analysis. This review followed a systematic approach where research papers were collected following a defined set of criteria. The study revealed 16 key utilization pathways, all of which showed promising results. However, a comprehensive sustainability assessment was lacking in all of the pathways. The second …


The Effect Of Herbal Adaptogen On Feeding-Related Hypothalamic Neuropeptides In Heat-Stressed Broilers, Maryam Afkhami Ardakani Aug 2023

The Effect Of Herbal Adaptogen On Feeding-Related Hypothalamic Neuropeptides In Heat-Stressed Broilers, Maryam Afkhami Ardakani

Graduate Theses and Dissertations

Heat stress is a major issue in the poultry industry, having numerous negative consequences for chicken productivity. Decreasing feed intake is one of these issues, which results in higher mortality and poor growth performance. Moreover, Herbal adaptogens, plant extracts that are also known as stress response modifiers, are metabolic regulators that improve an organism's ability to adapt to environmental stresses and minimize damage from such stressors. Previously, we published data indicating that herbal adaptogen supplementation increased feed intake under heat stress conditions. Therefore, we hypothesized that dietary herbal adaptogen supplementation might exert these effects through alteration of the expression of …


Chemostratigraphic And Paleoclimatic Studies Of Cloverly Formation, Northern Wyoming, U.S.A, Queen Amarachi Kalu Aug 2023

Chemostratigraphic And Paleoclimatic Studies Of Cloverly Formation, Northern Wyoming, U.S.A, Queen Amarachi Kalu

Graduate Theses and Dissertations

The Early – Late Cretaceous transition in Western North America recorded a period of rapid climatic and tectonic change in Earth’s history. Major climate events associated with large igneous province eruptions caused several instances of ocean anoxic events (OAE) and perturbations to the global carbon (C) – cycle. These perturbations to the global C-cycle are observed in the bulk organic C record of both marine and terrestrial deposits and can be used to correlate units across major depositional basins. Major efforts are being made to generate time-constrained palaeontologic and paleoclimate information from the North American Cordilleran foreland basin and C-isotope …


On Neo-Humean Accounts For Natural Laws, Tori Helen Cotton Aug 2023

On Neo-Humean Accounts For Natural Laws, Tori Helen Cotton

Graduate Theses and Dissertations

Humeanism about laws is a metaphysical doctrine that claims that the complete scope of the world is comprised of the mosaic—a vast collection of particular, localized facts about the world, and everything else supervenes on this arrangement of facts. Reductionism about laws, the claim that laws of nature reduce to, and thereby supervene on, the Humean mosaic, follows from this view. The first part of the thesis explores Humeanism about laws and the evolving landscape of pragmatic approaches within this domain. Building upon the insights gained from this analysis, the second part of the thesis proposes a novel response to …


Use Of X-Ray Imaging To Elucidate Impacts Of Drying Approach On Rice Seed Health, Samuel Olayiwola Olaoni Aug 2023

Use Of X-Ray Imaging To Elucidate Impacts Of Drying Approach On Rice Seed Health, Samuel Olayiwola Olaoni

Graduate Theses and Dissertations

Improper drying, which causes fissuring of rice kernels, may influence the overall seed health. This study evaluated the impacts of various drying conditions on rice fissures, seed germination and vigor. A long – grain rice cultivar with a moisture content (MC) of 15.5% w.b. (wet basis) was used during the experiments. Samples were dried as thin layers at temperatures of 30 ℃, 40 ℃ and 50 ℃ with a constant relative humidity (RH) of 50% and air velocities (AV) of 0.66 m/s and 1.65 m/s. X – ray imaging was used for fissure detection before and after drying the samples …


Phenotypic And Transcriptomic Characterization Of Rice Snrk1 Mutants Developed By Crispr/Cas9 Mutagenesis, Maria Clara Faria Chaves Aug 2023

Phenotypic And Transcriptomic Characterization Of Rice Snrk1 Mutants Developed By Crispr/Cas9 Mutagenesis, Maria Clara Faria Chaves

Graduate Theses and Dissertations

SnRK1 is a heterotrimeric protein kinase that is composed of a catalytic subunit (α) and two regulatory subunits (β and βγ), and it has a main role in regulating energy homeostasis in the plant by modulating anabolic and catabolic process. SnRK1 phosphorylates and alters the activities of enzymes involved in metabolism and regulates gene expression by altering the activity of chromatin-remodeling enzymes or the transcription factors. Rice contains three functional paralogs of SnRK1α: SnRK1αa (LOC_Os03g17980), SnRK1αb (LOC_Os08g37800), and SnRK1αc (LOC_Os05g45420). This study focused on the function of these SnRK1 paralogs by evaluating the phenotypic and transcriptomic characteristics and the disease …


Generating Health-Promoting Bioactive Compounds And Nanoporous Materials From Rice Processing Byproducts Via Supercritical Carbon Dioxide Technology, Sumanjot Kaur Aug 2023

Generating Health-Promoting Bioactive Compounds And Nanoporous Materials From Rice Processing Byproducts Via Supercritical Carbon Dioxide Technology, Sumanjot Kaur

Graduate Theses and Dissertations

Rice husk and bran, byproducts of rice processing, are generated in large quantities (~30-40% of the total rice weight) and are discarded as waste or burned in an open field, creating a major disposal problem for the rice industry. However, these byproducts contain high-value compounds, including phytochemicals, fiber, and proteins. Therefore, the goal of this study was to generate high-value food ingredients from rice processing byproducts using a green, innovative approach based on supercritical carbon dioxide (SC-CO2) technology. Specific objectives were to (i) extract health-promoting phytochemicals from rice husk and (ii) convert rice bran into nanoporous materials using SC-CO2. First, …


Music Can Be Reconstructed From Human Auditory Cortex Activity Using Nonlinear Decoding Models, Ludovic Bellier, Anaïs Llorens, Déborah Marciano, Aysegul Gunduz, Gerwin Schalk, Peter Brunner, Robert T. Knight Aug 2023

Music Can Be Reconstructed From Human Auditory Cortex Activity Using Nonlinear Decoding Models, Ludovic Bellier, Anaïs Llorens, Déborah Marciano, Aysegul Gunduz, Gerwin Schalk, Peter Brunner, Robert T. Knight

2020-Current year OA Pubs

Music is core to human experience, yet the precise neural dynamics underlying music perception remain unknown. We analyzed a unique intracranial electroencephalography (iEEG) dataset of 29 patients who listened to a Pink Floyd song and applied a stimulus reconstruction approach previously used in the speech domain. We successfully reconstructed a recognizable song from direct neural recordings and quantified the impact of different factors on decoding accuracy. Combining encoding and decoding analyses, we found a right-hemisphere dominance for music perception with a primary role of the superior temporal gyrus (STG), evidenced a new STG subregion tuned to musical rhythm, and defined …


Cullin 3–Mediated Regulation Of Intracellular Iron Homeostasis Promotes Thymic Invariant Nkt Cell Maturation, Emily L. Yarosz, Ajay Kumar, Jeffrey Singer, Cheong-Hee Chang Aug 2023

Cullin 3–Mediated Regulation Of Intracellular Iron Homeostasis Promotes Thymic Invariant Nkt Cell Maturation, Emily L. Yarosz, Ajay Kumar, Jeffrey Singer, Cheong-Hee Chang

Biology Faculty Publications and Presentations

The E3 ubiquitin ligase cullin 3 (Cul3) is critical for invariant NKT (iNKT) cell development, as iNKT cells lacking Cul3 accumulate in the immature developmental stages. However, the mechanisms by which Cul3 mediates iNKT cell development remain unknown. In this study, we investigated the role of Cul3 in both immature and mature thymic iNKT cells using a mouse model with a T cell–specific deletion of Cul3. We found that mature iNKT cells lacking Cul3 proliferated and died more than wild-type cells did. These cells also displayed increased glucose metabolism and autophagy. Interestingly, we found that tight regulation of iron homeostasis …


Linguistic Features Of Metaphor, Metonymy And Narrative Gap In “The Yellow Wallpaper:” A Literary Analysis, Sherry Kaye Ms. Aug 2023

Linguistic Features Of Metaphor, Metonymy And Narrative Gap In “The Yellow Wallpaper:” A Literary Analysis, Sherry Kaye Ms.

Electronic Theses and Dissertations

In 1890, Charlotte Perkins Gilman wrote a piece of fiction that reflected her personal experience for treatment of nervous exhaustion. The story she developed created controversy and comment after it was published and, years later, agitation among feminists who found allegories of truth in its narrative. This thesis explores the use of linguistic features employed by Gilman to establish cognitive connections between physical structures and social institutions, such as marriage and domesticity, that confine women within contractual obligations. Gilman’s use of extended metaphor challenges conventional conceptions of the home, inanimate objects, and institutional authority and her use of metonymy extrapolates …


Understanding The Role Of Sabp2-Interacting Protein (Sip) 428: An Nad+-Dependent Deacetylase Enzyme In Abiotic Stress Signaling Of Nicotiana Tabacum, Mariam Onabanjo Aug 2023

Understanding The Role Of Sabp2-Interacting Protein (Sip) 428: An Nad+-Dependent Deacetylase Enzyme In Abiotic Stress Signaling Of Nicotiana Tabacum, Mariam Onabanjo

Electronic Theses and Dissertations

Abiotic stresses are constantly rising and pose a very high risk to global agricultural productivity and food security. Some plants have evolved several innate pathways for defense against these stresses. Hence, understanding stress signaling pathways can help develop crop plants with higher stress tolerance. The salicylic acid-mediated signaling pathway is important in plants experiencing biotic and abiotic stresses. In previous studies, SABP2-Interacting Protein (SIP-428) has been shown to be a negative regular of plant growth under abiotic stress. This study aimed to investigate the roles of SIP-428 in the ROS signaling of tobacco plants. We investigated transgenic RNAi-silenced lines of …


Geometric Morphometric Analysis Of Modern Viperid Vertebrae Facilitates Identification Of Fossil Specimens, Lance D. Jessee Aug 2023

Geometric Morphometric Analysis Of Modern Viperid Vertebrae Facilitates Identification Of Fossil Specimens, Lance D. Jessee

Electronic Theses and Dissertations

Snake vertebrae are common in the fossil record, whereas cranial remains are generally fragile and rare. Consequently, vertebrae are the most commonly studied fossil element of snakes. However, identification of snake vertebrae can be problematic due to extensive variation. This study utilizes 2-D geometric morphometrics and canonical variates analysis to 1) reveal variation between genera and species and 2) classify vertebrae of modern and fossil eastern North American Agkistrodon and Crotalus. The results show that vertebrae of Agkistrodon and Crotalus can reliably be classified to genus and species using these methods. Based on the statistical analyses, four of the …


Investigation Of The Protein Components In A Periplasmic Mechanism Regulating Bacterial Morphology, Alexandra Pulliam Aug 2023

Investigation Of The Protein Components In A Periplasmic Mechanism Regulating Bacterial Morphology, Alexandra Pulliam

Electronic Theses and Dissertations

Salmonella is a leading bacterial cause of foodborne illness worldwide. During a previous study investigating the enzymes responsible for regulating cyclic-di-GMP concentrations, a mutant in the cyclic-di-GMP-specific phosphodiesterase STM3615 was identified that displayed a phenotype characterized by decreased survival on agar plates and a shorter bacterium length. I was able to determine that the periplasmic domain of STM3615 was responsible for this phenotype, not the enzymatic phosphodiesterase domain. Based upon a bioinformatic analysis of the protein, I then hypothesized that the periplasmic domain of STM3615 was interacting with a periplasmic protein to give rise to this phenotype. To identify this …


Extraction, Purification, And Characterization Of Potential Bioactive Compounds Produced By Janthinobacterium Lividum Tajx1901, Andy Elorm Agbakpo Aug 2023

Extraction, Purification, And Characterization Of Potential Bioactive Compounds Produced By Janthinobacterium Lividum Tajx1901, Andy Elorm Agbakpo

Electronic Theses and Dissertations

Underexplored environments such as soil samples continue to be an untapped source of bacterial strains with great potential to produce secondary metabolites for medicinal applications. As a result, these microorganisms represent a broad and yet unknown reservoir of new strains capable of producing these novel compounds. The current research primarily seeks to perform the isolation, purification, and characterization of secondary metabolites from a soil bacterium (Janthinobacterium lividum TAJX1901). The isolated soil bacterium was successfully cultured on rich media agar plates, followed by extraction using methanol and chloroform. The purification methods utilized include flash column chromatography, preparative thin-layer chromatography, and …


Isolation And Structural Determination Of Bioactive Metabolites From The Soil Bacterium, Arthrobacter Sp. Tajx1902, Amonah Arije Aug 2023

Isolation And Structural Determination Of Bioactive Metabolites From The Soil Bacterium, Arthrobacter Sp. Tajx1902, Amonah Arije

Electronic Theses and Dissertations

As antimicrobial resistance persistently disrupts the treatment of microbial infection, natural product chemistry has played a significant role in identifying novel drugs with novel modes of action critical to getting ahead of resistance. The primary goal of this project is to extract and identify potential novel antimicrobial natural products produced by Arthrobacter sp. Although underexplored, Arthrobacter sps. have been known to produce bioactive compounds with versatility; one such is a depsipeptide with quorum-sensing inhibitory activity.1 In this research, an Arthrobacter sp. TAJX1902, isolated from a soil sample, showed inhibitory activity against a filamentous indicator bacterium and a violacein-producing Janthinobacterium …


A Manual For The Recovery Of Cbrne (Chemical, Biological, Radiological, Nuclear, And Explosive) Contaminated Human Remains, Patrick Barchett Aug 2023

A Manual For The Recovery Of Cbrne (Chemical, Biological, Radiological, Nuclear, And Explosive) Contaminated Human Remains, Patrick Barchett

Department of Anthropology: Theses and Student Research

Despite many international agreements and treaties prohibiting the use of CBRNE (Chemical, Biological, Radiological, Nuclear, and Explosive) weaponry, the proliferation of contaminated human remains displays the historic and continued use of inhumane war efforts. Due to the complications of recovery, contaminated human remains are often left unrecovered and unidentified. This thesis works to create a framework for the recovery of contaminated human remains for organizations with a focus on creating safe and sustainable working environments for those conducting the recovery. Much of this thesis assumes the remains are being recovered from interred mass graves. This thesis provides an introduction to …


Physiological, Ecological, And Microbial Factors Shaping Thermal Tolerance And Performance In Ectothermic Vertebrates, Jason Warren Dallas Aug 2023

Physiological, Ecological, And Microbial Factors Shaping Thermal Tolerance And Performance In Ectothermic Vertebrates, Jason Warren Dallas

Dissertations

Temperature represents a major driving force in biology as it influences essential functions across multiple levels of biological organization. The role of temperature is especially important for ectothermic animals, whose biotic processes are dependent on both body and environmental temperature. Assessing the relationship between temperature and organismal performance represents an important research direction as temperatures continue to warm under anthropogenic climate change. Chapters two and three are focused on a recently colonized population of the invasive Mediterranean House Geckos at the northern edge of their invasion front. These chapters examine the ecological and physiological factors that enable these lizards to …


Occupancy And Activity Patterns Of Nine-Banded Armadillos (Dasypus Novemcinctus) In A Suburban Environment, Brett Degregorio, Matthew R. Mcelroy, Emily P. Johansson Aug 2023

Occupancy And Activity Patterns Of Nine-Banded Armadillos (Dasypus Novemcinctus) In A Suburban Environment, Brett Degregorio, Matthew R. Mcelroy, Emily P. Johansson

Biological Sciences Faculty Publications and Presentations

The geographic range of the nine-banded armadillo (Dasypus novemcinctus) has rapidly been expanding within the United States for the last 150 years. One of the factors contributing to this astounding range expansion is the species’ ability to survive in and colonize human-dominated areas. Despite the fact that armadillos live alongside humans in numerous towns and cities across the Southeastern, Southcentral, and now Midwestern United States, we know relatively little about the behavior and ecology of armadillos in human-developed areas. Here, we used motion-triggered game cameras in over 115 residential yards in the rapidly developing Northwest corner of Arkansas …


Heterochiral Dna Nanotechnology For Biomedical Applications, Tracy L. Mallette Aug 2023

Heterochiral Dna Nanotechnology For Biomedical Applications, Tracy L. Mallette

Biomedical Engineering ETDs

In the past 30 years, there have been major advancements on how to treat and diagnose disease because of the improvement and increase in accessibility of sequencing technology. Nucleic acid-based therapeutics can manipulate protein expression. Likewise, pathogens can be identified and detected with single nucleotide specificity. However, the underlying oligonucleotide technology requires protection against natural defense systems that have evolved to destroy foreign nucleic acids. Many chemical modifications that can protect nucleotides also have significant cytotoxic side effects and must be carefully designed into the strands. A novel way to protect against nuclease-mediated degradation is through the use of mirror-image, …


The Care Of Transgender Patients In Critical Care: A Call To Action, L Flower, A Humphreys, S Edwardson Aug 2023

The Care Of Transgender Patients In Critical Care: A Call To Action, L Flower, A Humphreys, S Edwardson

Peninsula Medical School

No abstract provided.


High Altitude Exercise, Autophagy, And Angiogenesis, Quint Nikolas Berkemeier Aug 2023

High Altitude Exercise, Autophagy, And Angiogenesis, Quint Nikolas Berkemeier

Health, Exercise, and Sports Sciences ETDs

Environmental hypoxia, as a result of decreased barometric pressure upon ascent to high altitudes (>2500m) presents increased physiological demands compared to low altitudes. Competitive athletes, mountaineers, wildland firefighters, military personnel, miners, and outdoor enthusiasts commonly participate in, or are exposed to, forms of exercise or physical labor at moderate to high altitudes. Interestingly, however, the majority of research on intermittent hypoxic exposure is centered around hematological markers and the skeletal muscle cellular responses to exercise in hypoxic environments remain largely unknown. Two processes that are integral for maintenance of cellular health in skeletal muscle include autophagy and angiogenesis. We …


Electromagnetic Simulations Of The Lansce Chopper Structure, Yusuf Sahin Aug 2023

Electromagnetic Simulations Of The Lansce Chopper Structure, Yusuf Sahin

Electrical and Computer Engineering ETDs

Particle accelerators are important for basic research as well as in applications such as ion implantation and cancer therapy. One important accelerator is the Los Alamos Neutron Science Center (LANSCE) located at Los Alamos National Laboratory (LANL) that primarily produces neutrons for research. The beam chopper simulation described here is a study to provide better modeling of this subsystem of LANSCE. A chopper is a device in which particles are intermittently sliced and directed to a target and/or experiment. The simulations in this thesis are used to analyze the correct operating parameters of the chopper. A good chopper model can …


Myeloid Fth1 Deficiency Protects Mice From Colitis And Colitis-Associated Colorectal Cancer Via Reducing Dmt1-Imported Iron And Stat3 Activation, Zhaoli Liu, Mariella Arcos, David R. Martin, Xiang Xue Aug 2023

Myeloid Fth1 Deficiency Protects Mice From Colitis And Colitis-Associated Colorectal Cancer Via Reducing Dmt1-Imported Iron And Stat3 Activation, Zhaoli Liu, Mariella Arcos, David R. Martin, Xiang Xue

Pathology Research and Scholarship

BACKGROUND: Myeloid cells are critical for iron and immune homeostasis. Ferritin heavy chain (FTH1) is essential for intracellular iron storage. Myeloid FTH1 is important in the pathogenesis of many inflammatory diseases. However, the role of myeloid FTH1 in colitis and colitis-associated cancer has not been determined.

METHODS: Myeloid FTH1 deficient and wild-type mice were treated with dextran sodium sulfate (DSS) or azoxymethane (AOM)-DSS to compare their susceptibility to acute colitis or colitis-associated cancer.

RESULTS: Myeloid FTH1-deficient mice fed with a high-iron diet were less susceptible to DSS-induced acute colitis than wild type mice. Mechanistic studies showed that myeloid FTH1 deficiency …


Immigrational Trauma: An Assessment Of Dental Phobia And Access To Care In Undocumented Individuals, Nora J. Vences Ortiz Aug 2023

Immigrational Trauma: An Assessment Of Dental Phobia And Access To Care In Undocumented Individuals, Nora J. Vences Ortiz

Dental Hygiene ETDs

The purpose of this study is to assess immigrational trauma as it relates to dental phobia in accessing care from undocumented individuals. Immigrating from a country to the United States presents with unique challenges. These challenges include language barriers, traumatic experiences and cultural factors. These individuals also have perceived notions regarding their treatment with a physician or dentist as their immigration status may or may not be revealed during their care. If reported, they face deportation to their country of origin placing them in the danger they originally fled from. Survey data was collected using REDCap and distributed to students …