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2023

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Enrollment Of Underrepresented Racial And Ethnic Groups In The Rare And Atypical Diabetes Network (Radiant), Mustafa Tosur, Laura Gandolfo, Ashok Balasubramanyam, Rochelle N Naylor, Toni I Pollin, Neda Rasouli, Sara J Cromer, John B Buse, Maria J Redondo, Radiant Study Group Jan 2023

Enrollment Of Underrepresented Racial And Ethnic Groups In The Rare And Atypical Diabetes Network (Radiant), Mustafa Tosur, Laura Gandolfo, Ashok Balasubramanyam, Rochelle N Naylor, Toni I Pollin, Neda Rasouli, Sara J Cromer, John B Buse, Maria J Redondo, Radiant Study Group

Faculty, Staff and Students Publications

INTRODUCTION: Diabetes mellitus in underrepresented racial and ethnic groups (URG) is rapidly increasing in incidence and has worse outcomes than diabetes in non-Hispanic White individuals. Rare and Atypical Diabetes Network (RADIANT) established recruitment targets based on the racial and ethnic distribution of the USA to enroll a diverse study population. We examined participation of URG across RADIANT study stages and described strategies to enhance recruitment and retention of URG.

MATERIALS AND METHODS: RADIANT is a multicenter NIH-funded study of people with uncharacterized forms of atypical diabetes. RADIANT participants consent online and progress through three sequential study stages, as eligible.

RESULTS: …


Evaluating The Use Of Reflective Practice Principles To Support Nurse Manager Well-Being During A Period Of Chronic Distress, Amy A. Martone Jan 2023

Evaluating The Use Of Reflective Practice Principles To Support Nurse Manager Well-Being During A Period Of Chronic Distress, Amy A. Martone

Yale School of Nursing Digital Theses

The COVID-19 pandemic brought forward a crisis that the current U.S. healthcare system was not prepared for. This increased the risk for burnout of teams and individuals, including the nurse leader. Nurse managers were selected as the target audience for support because they are key clinical leaders at the unit and staff level, yet they report feeling undervalued and are at higher risk for turnover than other leaders. This project developed a program that used reflective practice principles to support nurse manager well-being during periods of chronic distress.

The curriculum was guided by the Dimensions of Leadership as framework for …


Enhancement In Strength Parameters Of Mortar By Application Of Bacillus Bacteria, A.A. Maaty, M.F. Ghazy, Y. El-Halmouch, G.R. Gadallah Jan 2023

Enhancement In Strength Parameters Of Mortar By Application Of Bacillus Bacteria, A.A. Maaty, M.F. Ghazy, Y. El-Halmouch, G.R. Gadallah

Mansoura Engineering Journal

Cracks in concrete often occur because of environmental factors like moisture, chemical attacks, and temperature changes. This study investigates utilizing microbial induced calcite precipitation (MICP) to address concrete cracking. Bacillus Sphaericus strain is introduced into cement mortar to enhance its physical and mechanical properties, focusing on crack healing. (MICP) microbial induced calcite precipitation reduces water absorption and capillary coefficient by filling cracks with calcium carbonate using bacterial nutrients. After a duration of 90 days, the bacterial samples exhibit a noteworthy decrease in both capillary action and water absorption when contrasted with the control samples. The bacterial mortar demonstrates accelerated progress …


Deep Learning-Based Technique For The Perception Of The Cervical Cancer, Aya Haraz, Hossam El-Din Moustafa, Abeer Twakol Khaleel, Ahmed H. Eltanboly Jan 2023

Deep Learning-Based Technique For The Perception Of The Cervical Cancer, Aya Haraz, Hossam El-Din Moustafa, Abeer Twakol Khaleel, Ahmed H. Eltanboly

Mansoura Engineering Journal

In third-world countries, cervical cancer is the most prevalent and leading cause of death. It is affected by a variety of factors, including smoking, poor nutritional status, immunological inadequacy, and prolonged use of contraception. The Pap smear test, which is intended to prevent cervical cancer, finds preneoplastic changes in cervical epithelial cells. This study framework classified cervical cancer cells from Pap smears into five specified cell types using machine learning-based classification algorithms. The SIPaKMeD database is used in this investigation. This public dataset, which was manually cropped from 966 cluster cell images taken from Pap smear slides, has 4045 isolated …


Vitamin D Supplementation And Exercise For Improving Physical Function, Body Composition And Metabolic Health In Overweight Or Obese Older Adults With Vitamin D Deficiency: A Pilot Randomized, Double-Blind, Placebo-Controlled Trial, Jakub Mesinovic, Alexander J. Rodriguez, Mavil May Cervo, Anoohya Gandham, Cecilia L. H. Xu, Costas Glavas, Barbora De Courten, Ayse Zengin, Peter R. Ebeling, David Scott Jan 2023

Vitamin D Supplementation And Exercise For Improving Physical Function, Body Composition And Metabolic Health In Overweight Or Obese Older Adults With Vitamin D Deficiency: A Pilot Randomized, Double-Blind, Placebo-Controlled Trial, Jakub Mesinovic, Alexander J. Rodriguez, Mavil May Cervo, Anoohya Gandham, Cecilia L. H. Xu, Costas Glavas, Barbora De Courten, Ayse Zengin, Peter R. Ebeling, David Scott

Research outputs 2022 to 2026

Purpose:

Vitamin D supplementation may have non-skeletal health benefits and enhance exercise responsiveness, particularly in those with low vitamin D levels. We determined whether, compared with placebo, vitamin D supplementation taken prior to and during a 12-week exercise program improves physical function, body composition or metabolic health, in overweight and obese older adults with vitamin D deficiency.

Methods:

Fifty overweight or obese older adults (mean ± SD age: 60 ± 6 years; BMI 30.6 ± 5.7 kg/m2) with vitamin D deficiency (25-hydroxyvitamin D [25(OH)D] < 50 nmol/L) were recruited. Participants were randomly allocated to receive either vitamin D3 (4000 IU/day) or matching placebo for 24 weeks. Between weeks 12 and 24, all participants completed multi-modal exercise three days per week while continuing with vitamin D/placebo. Mean changes in physical function (primary outcome: gait speed), body composition and biochemical parameters at weeks 12 and 24 were compared between groups.

Results:

Vitamin D supplementation, with or without exercise, had no effect on gait speed. From baseline …


Deciphering The Salivary Microbiome In Crohn’S Disease Patients With Different Factors Contributing To Dysbiosis, Hala Elzayat Jan 2023

Deciphering The Salivary Microbiome In Crohn’S Disease Patients With Different Factors Contributing To Dysbiosis, Hala Elzayat

Theses

Crohn’s Disease (CD) is a chronic Inflammatory Bowel Disease (IBD), common in the UAE. Microbiota is necessary to maintain a balanced gut environment which is essential for good health. Dysbiosis can predispose to many diseases including CD. The oral cavity has the second largest and most diverse microbiota after the gut harboring over 700 species of bacteria. This study aims to investigate the alterations in the salivary microbiome in patients with CD compared to Healthy controls (HC). It also aims to compare CD patients for salivary microbiome complexity and diversity according to different factors that can contribute to dysbiosis, including …


Nrg/Rtog 0837: Randomized, Phase Ii, Double-Blind, Placebo-Controlled Trial Of Chemoradiation With Or Without Cediranib In Newly Diagnosed Glioblastoma, Tracy T Batchelor, Clifford G Robinson, Et Al. Jan 2023

Nrg/Rtog 0837: Randomized, Phase Ii, Double-Blind, Placebo-Controlled Trial Of Chemoradiation With Or Without Cediranib In Newly Diagnosed Glioblastoma, Tracy T Batchelor, Clifford G Robinson, Et Al.

2020-Current year OA Pubs

BACKGROUND: A randomized, phase II, placebo-controlled, and blinded clinical trial (NCT01062425) was conducted to determine the efficacy of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, versus placebo in combination with radiation and temozolomide in newly diagnosed glioblastoma.

METHODS: Patients with newly diagnosed glioblastoma were randomly assigned 2:1 to receive (1) cediranib (20 mg) in combination with radiation and temozolomide; (2) placebo in combination with radiation and temozolomide. The primary endpoint was 6-month progression-free survival (PFS) based on blinded, independent radiographic assessment of postcontrast T1-weighted and noncontrast T2-weighted MRI brain scans and was tested using a 1-sided …


Clinical Characteristics And Outcomes Of Infection With Human T-Lymphotropic Virus In A Non-Endemic Area: A Single Institution Study, Margery Gang, Feng Gao, Sneha Poondru, Theodore Thomas, Lee Ratner Jan 2023

Clinical Characteristics And Outcomes Of Infection With Human T-Lymphotropic Virus In A Non-Endemic Area: A Single Institution Study, Margery Gang, Feng Gao, Sneha Poondru, Theodore Thomas, Lee Ratner

2020-Current year OA Pubs

INTRODUCTION: Understanding of human T-lymphotropic virus (HTLV) remains largely based on epidemiologic and clinical data from endemic areas. Globalization has resulted in migration of persons living with HTLV (PLHTLV) from endemic to non-endemic areas, and a rise of HTLV infection in the United States. Yet, due to the historical rarity of this disease, affected patients are often under- and mis-diagnosed. Thus, we sought to characterize the epidemiology, clinical features, comorbidities, and survival of HTLV-1- or HTLV-2-positive individuals identified in a non-endemic area.

METHODS: Our study was a single institution, retrospective case-control analysis of HTLV-1 or HTLV-2 patients between 1998 and …


Adapting A Mobile App To Support Patients With Anorexia Nervosa Following Post-Acute Care: Perspectives From Eating Disorder Treatment Center Stakeholders, Anneliese Haas, Agatha A Laboe, Claire G Mcginnis, Marie-Laure Firebaugh, Jillian Shah, Anna M Bardone-Cone, Kathleen M Pike, C Barr Taylor, Denise E Wilfley, Ellen E Fitzsimmons-Craft Jan 2023

Adapting A Mobile App To Support Patients With Anorexia Nervosa Following Post-Acute Care: Perspectives From Eating Disorder Treatment Center Stakeholders, Anneliese Haas, Agatha A Laboe, Claire G Mcginnis, Marie-Laure Firebaugh, Jillian Shah, Anna M Bardone-Cone, Kathleen M Pike, C Barr Taylor, Denise E Wilfley, Ellen E Fitzsimmons-Craft

2020-Current year OA Pubs

INTRODUCTION: Anorexia nervosa (AN) is a harmful, life-threatening illness. Patients with severe AN often receive acute treatment but, upon discharge, experience high relapse rates. Evidence-based, outpatient treatment following acute care is critical to preventing relapse; however, numerous barriers (e.g., location, financial limitations, low availability of providers) preclude individuals from accessing treatment. mHealth technologies may help to address these barriers, but research on such digital approaches for those with AN is limited. Further, such technologies should be developed with all relevant stakeholder input considered from the outset. As such, the present study aimed to garner feedback from eating disorder (ED) treatment …


Development Of A Peripheral Blood Transcriptomic Gene Signature To Predict Bronchopulmonary Dysplasia, Alvaro Moreira, Miriam Tovar, Alisha M Smith, Grace C Lee, Justin A Meunier, Zoya Cheema, Axel Moreira, Caitlyn Winter, Shamimunisa B Mustafa, Steven Seidner, Tina Findley, Joe G N Garcia, Bernard Thébaud, Przemko Kwinta, Sunil K Ahuja Jan 2023

Development Of A Peripheral Blood Transcriptomic Gene Signature To Predict Bronchopulmonary Dysplasia, Alvaro Moreira, Miriam Tovar, Alisha M Smith, Grace C Lee, Justin A Meunier, Zoya Cheema, Axel Moreira, Caitlyn Winter, Shamimunisa B Mustafa, Steven Seidner, Tina Findley, Joe G N Garcia, Bernard Thébaud, Przemko Kwinta, Sunil K Ahuja

Faculty, Staff and Students Publications

Bronchopulmonary dysplasia (BPD) is the most common lung disease of extreme prematurity, yet mechanisms that associate with or identify neonates with increased susceptibility for BPD are largely unknown. Combining artificial intelligence with gene expression data is a novel approach that may assist in better understanding mechanisms underpinning chronic lung disease and in stratifying patients at greater risk for BPD. The objective of this study is to develop an early peripheral blood transcriptomic signature that can predict preterm neonates at risk for developing BPD. Secondary analysis of whole blood microarray data from 97 very low birth weight neonates on day of …


Nourishing The Brain On Deep Space Missions: Nutritional Psychiatry In Promoting Resilience, Nihar N Pathare, Flavia Fayet-Moore, Jennifer A Fogarty, Felice N Jacka, Philip Strandwitz, Gary E Strangman, Dorit B Donoviel Jan 2023

Nourishing The Brain On Deep Space Missions: Nutritional Psychiatry In Promoting Resilience, Nihar N Pathare, Flavia Fayet-Moore, Jennifer A Fogarty, Felice N Jacka, Philip Strandwitz, Gary E Strangman, Dorit B Donoviel

Faculty, Staff and Students Publications

The grueling psychological demands of a journey into deep space coupled with ever-increasing distances away from home pose a unique problem: how can we best take advantage of the benefits of fresh foods in a place that has none? Here, we consider the biggest challenges associated with our current spaceflight food system, highlight the importance of supporting optimal brain health on missions into deep space, and discuss evidence about food components that impact brain health. We propose a future food system that leverages the gut microbiota that can be individually tailored to best support the brain and mental health of …


An Innovative State-Of-The-Art Health Storytelling Technique For Better Management Of Type 2 Diabetes, Sumbal Ali, Shumaila Bakht, Atta Ullah Jan, Iftikhar Alam, Ali Madi Almajwal, Tareq Osaili, Reyad Shakir Obaid, Moez Allslam Ezzat Faris, Leila Cheikh Ismail, Farah Najah, Hadia Radwan, Haydar Hasan, Mona Hashim, Sharifa Alblooshi, Bismillah Sehar, Falak Zeb Jan 2023

An Innovative State-Of-The-Art Health Storytelling Technique For Better Management Of Type 2 Diabetes, Sumbal Ali, Shumaila Bakht, Atta Ullah Jan, Iftikhar Alam, Ali Madi Almajwal, Tareq Osaili, Reyad Shakir Obaid, Moez Allslam Ezzat Faris, Leila Cheikh Ismail, Farah Najah, Hadia Radwan, Haydar Hasan, Mona Hashim, Sharifa Alblooshi, Bismillah Sehar, Falak Zeb

All Works

Background: Type 2 diabetes (T2D) is a chronic lifelong disease that requires long-term prevention and management strategies in a community setting. A health story is a novel technique that may be used as an effective tool for better prevention and management of T2D. Objective: The main objective of this study is to develop a story to be used as a social health technique based on contemporary scientific knowledge that may be used at a community level for better communication and management of T2D. Methods: A community–academic partnership was formed with a not-for-profit Nutrition Education, Awareness, and Training (NEAT) organization in …


Understanding Perceptions Of New-Onset Type 1 Diabetes Education In A Pediatric Tertiary Care Center, Gabriel Betancurvelez Jan 2023

Understanding Perceptions Of New-Onset Type 1 Diabetes Education In A Pediatric Tertiary Care Center, Gabriel Betancurvelez

Yale Medicine Thesis Digital Library

Background: Youth newly diagnosed with type 1 diabetes (T1D), and their families, require intensive education on the management of this chronic condition during this overwhelming period. Traditionally, our center conducts training in person during a hospital admission.

Methods: We studied family perceptions of our current patient education methods in an effort to elucidate strategies to augment education in the post-pandemic environment, where provider time in the room and visitation rules may limit face-to-face encounters.

Results: 25 families completed the survey (distributed to 156 in total, with approximately 21% response rate). The mean age at diagnosis was 9.52 ± 4.29 years …


The Association Between Social Needs Care Coordination And Social Needs Status Amongst Patients In A Federally Qualified Health Center, Autumn Nobles Jan 2023

The Association Between Social Needs Care Coordination And Social Needs Status Amongst Patients In A Federally Qualified Health Center, Autumn Nobles

Yale Medicine Thesis Digital Library

Social needs screenings within healthcare systems have grown more common with increasing discourse around the contribution of systemic determinants to health outcomes. These screenings have been used to describe the prevalence of social needs within communities but have not been evaluated for the impact that they and the interventions to which they are attached may have on health outcomes. Here we evaluate social needs screenings and their potential impact on patient health at a federally qualified health center in New Haven, Connecticut. We describe the baseline needs at the facility, evaluate change in reported social needs among patients undergoing screening, …


Examining Foods And Beverages Served And Child Food Insecurity Across Early Care And Education (Ece) Programs In Communities With High Rates Of Obesity And Food Insecurity, Deepa Srivastava, Lucy R. Zheng, Dipti A. Dev Jan 2023

Examining Foods And Beverages Served And Child Food Insecurity Across Early Care And Education (Ece) Programs In Communities With High Rates Of Obesity And Food Insecurity, Deepa Srivastava, Lucy R. Zheng, Dipti A. Dev

Department of Child, Youth, and Family Studies: Faculty Publications

The purpose of this study was to examine implementation of serving food and beverage evidence-based practices (nutrition EBPs) across CACFP participating licensed childcare centers (CCCs, n = 51) and family childcare homes (FCCHs, n = 49) in central California. Results indicated that FCCHs reported significantly higher (p < .05) implementation of nutrition EBPs and barriers than CCCs. Both CCCs and FCCHs refer families to WIC/SNAP when they observe child food insecurity and control how much food is served to children. It is important to consider organizational structure (CCCs, FCCHs) and child food insecurity when developing policies/interventions for improving implementation of nutrition EBPs in ECEs.


Cell Signaling And Stress Response In The Yeast Saccharomyces Cerevisiae: A Study Of Snf1, Scott E. Arbet Ii Jan 2023

Cell Signaling And Stress Response In The Yeast Saccharomyces Cerevisiae: A Study Of Snf1, Scott E. Arbet Ii

Graduate Theses, Dissertations, and Problem Reports (ETD)

Saccharomyces cerevisiae are yeast that are unicellular eukaryotic organisms that are well studied as a model organism for understanding fundamental cellular processes. The ability of yeast to sense nutrient availability is crucial for their survival, growth, and reproduction. Yeast cells use various mechanisms to sense and respond to nutrient availability, including transporter-mediated uptake, receptor-mediated signaling, and sensing of metabolites. The subcellular localization of nutrient-sensing components is crucial for yeast function in nutrient sensing and signaling. Protein complexes, such as the AMP-activated protein kinase (AMPK) pathway, in nutrient sensing and response, as well as the downstream effects of these pathways …


The Investigation Of Novel Bovine Oocyte-Specific Long Non-Coding Rnas And Their Roles In Oocyte Maturation And Early Embryonic Development, Jaelyn Zoe Current Jan 2023

The Investigation Of Novel Bovine Oocyte-Specific Long Non-Coding Rnas And Their Roles In Oocyte Maturation And Early Embryonic Development, Jaelyn Zoe Current

Graduate Theses, Dissertations, and Problem Reports (ETD)

Early embryonic loss is a significant factor in livestock species' infertility, resulting in an economic deficit. In cattle, the in vivo fertilization rate is ~90%, with an average calving rate of about 55%, indicating an embryonic-fetal mortality rate of roughly 35%. Further, 70-80% of total embryonic loss in cattle occurs during the first three weeks after insemination, particularly between days 7-16. Growing evidence indicates that the oocyte plays an active role in regulating critical aspects of the reproductive process required for successful fertilization, embryo development, and pregnancy. However, defining oocyte quality remains enigmatic. Recently, many have abandoned the notion that …


Public Reporting Of Monitorship Outcomes, Veronica Root Martinez Jan 2023

Public Reporting Of Monitorship Outcomes, Veronica Root Martinez

Faculty Scholarship

When a corporation engages in misconduct that is widespread or pervasive, courts, regulators, or prosecutors often insist that the firm obtain assistance from an independent third party — a monitor — to oversee the firm’s remediation effort. The largest firms in the world — from Deutsche Bank, to Volkswagen, to Carnival Cruise Lines — have found themselves having to retain a monitor for corporate misconduct, despite attempts to avoid a monitorship entirely. Traditionally, monitors, or their special master forebearers, were utilized by courts to assist in overseeing compliance with court orders, and their work was both accessible and transparent. As …


Acute Effects Of Sprint Interval Training And Blood Flow Restriction On Neuromuscular And Muscle Function, David Gonzalez Rojas Jan 2023

Acute Effects Of Sprint Interval Training And Blood Flow Restriction On Neuromuscular And Muscle Function, David Gonzalez Rojas

Electronic Theses and Dissertations, 2020-2023

The purpose of this investigation was to examine the effects of continuous (CBFR) and intermittent (IBFR) blood flow restriction (BFR) applied during sprint interval training (SIT) on performance, muscle, and neuromuscular function. Fifteen men completed SIT with CBFR, IBFR, and No-BFR. Each SIT bout consisted of 2, 30-s maximal sprints on a cycle ergometer with a resistance of 7.5% of body mass. Concentric peak torque (CPT), maximal voluntary isometric contraction (MVIC) torque, and muscle thickness (MT) were measured before and after the SIT protocols during each visit. During the maximal strength assessments, surface electromyography (sEMG) was recorded and during each …


Cognitive Rehabilitation And Aerobic Exercise For Cognitive Impairment In People With Progressive Multiple Sclerosis (Cogex): A Randomised, Blinded, Sham-Controlled Trial, Anthony Feinstein, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Robert W. Motl, Maria A. Rocca, Brian M. Sandroff, Amber Salter, Alex Pietrusz, Andrea Tacchino, A Smith, Anne Sophie Michelsen, Ashlie Kristin, Blake Bichler, Brendon Truax, Carmen Vizzino, Catherine Danielle Jones, Catherine Holme, C Smith, Charly Keytsman, Chiara Pollio, Chris Cole, Claudia Niccolai, Claudio Cordani, Eleonora Colombo, Elisa Pelosin, Ellen Vanzeir, Fedrica Vannetti, Filippo Gerli, Francesco Maranta, Gianna Riccitelli, Guido Pasquini, Holly Wilkinson, Irene Mosca, James Braisher, Jessica Baird, Jessica Podda, Jimmy Morecraft, Joke Lenaerts, Juliana Puopolo, K Algie, L Kenton, L Toll, Lt Madsen, L Knevels, L Lee, L Pedullà, M Cellerino, James Braisher, M-Lk Jørgensen, M Pardini, M Sibilia, M Nabarro, Md Diedmann, M Dibenedetto, M Curran, M Koch, M D'Hooge, N Moore, Nd Weerdt, P Preziosa, P Pajak, P Silic, Rb Walters, R Finegan, R Veldkamp, R Hernandez, R Donnee, S Casagrande, S Lancia, Sd Bella, S Vandecasteele, V Vandael Jan 2023

Cognitive Rehabilitation And Aerobic Exercise For Cognitive Impairment In People With Progressive Multiple Sclerosis (Cogex): A Randomised, Blinded, Sham-Controlled Trial, Anthony Feinstein, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Robert W. Motl, Maria A. Rocca, Brian M. Sandroff, Amber Salter, Alex Pietrusz, Andrea Tacchino, A Smith, Anne Sophie Michelsen, Ashlie Kristin, Blake Bichler, Brendon Truax, Carmen Vizzino, Catherine Danielle Jones, Catherine Holme, C Smith, Charly Keytsman, Chiara Pollio, Chris Cole, Claudia Niccolai, Claudio Cordani, Eleonora Colombo, Elisa Pelosin, Ellen Vanzeir, Fedrica Vannetti, Filippo Gerli, Francesco Maranta, Gianna Riccitelli, Guido Pasquini, Holly Wilkinson, Irene Mosca, James Braisher, Jessica Baird, Jessica Podda, Jimmy Morecraft, Joke Lenaerts, Juliana Puopolo, K Algie, L Kenton, L Toll, Lt Madsen, L Knevels, L Lee, L Pedullà, M Cellerino, James Braisher, M-Lk Jørgensen, M Pardini, M Sibilia, M Nabarro, Md Diedmann, M Dibenedetto, M Curran, M Koch, M D'Hooge, N Moore, Nd Weerdt, P Preziosa, P Pajak, P Silic, Rb Walters, R Finegan, R Veldkamp, R Hernandez, R Donnee, S Casagrande, S Lancia, Sd Bella, S Vandecasteele, V Vandael

School of Health Professions

Background Cognitive dysfunction in people with relapsing-remitting multiple sclerosis can improve with cognitive rehabilitation or exercise. Similar effects have not been clearly shown in people with progressive multiple sclerosis. We aimed to investigate the individual and synergistic effects of cognitive rehabilitation and exercise in patients with progressive multiple sclerosis. Methods CogEx was a randomised, sham-controlled trial completed in 11 hospital clinics, universities, and rehabilitation centres in Belgium, Canada, Denmark, Italy, UK, and USA. Patients with progressive multiple sclerosis were eligible for inclusion if they were aged 25–65 years and had an Expanded Disability Status Scale (EDSS) score of less than …


Rice Biomass Response To Various Phosphorus Fertilizers In A Phosphorus-Deficient Soil Under Simulated Furrow-Irrigation, Jonathan B. Brye, Kristofor R. Brye, Diego Della Lunga Jan 2023

Rice Biomass Response To Various Phosphorus Fertilizers In A Phosphorus-Deficient Soil Under Simulated Furrow-Irrigation, Jonathan B. Brye, Kristofor R. Brye, Diego Della Lunga

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Wastewater-recovered phosphorus (P), in the form of the mineral struvite (MgNH4PO4∙6H2O), may provide a sustainable alternative to decreasing rock-phosphate reserves. Struvite can be generated via precipitation methods, potentially reducing the amount of P runoff to aquatic ecosystems. The objective of this greenhouse tub study was to evaluate the effects of chemically and electrochemically precipitated struvite (CPST and ECST, respectively) on aboveground plant response in a hybrid rice cultivar grown using furrow-irrigation compared to other common fertilizer-P sources [i.e., triple super phosphate (TSP) and diammonium phosphate (DAP)] using three replications of fertilizer treatment in a P-deficient silt loam (Typic Glossaqualfs). Aboveground …


Comment On: Association Between Vitamin D And Cardiovascular Health: Myth Or Fact? A Narrative Review Of The Evidence, William B. Grant, Fatme Al Anouti, Barbara J. Boucher Jan 2023

Comment On: Association Between Vitamin D And Cardiovascular Health: Myth Or Fact? A Narrative Review Of The Evidence, William B. Grant, Fatme Al Anouti, Barbara J. Boucher

All Works

No abstract provided.


Association Of The Gut Microbiota With Clinical Variables In Obese And Lean Emirati Subjects, Manal Ali Ahmad, Mirey Karavetian, Carole Ayoub Moubareck, Gabi Wazz, Tarek Mahdy, Koen Venema Jan 2023

Association Of The Gut Microbiota With Clinical Variables In Obese And Lean Emirati Subjects, Manal Ali Ahmad, Mirey Karavetian, Carole Ayoub Moubareck, Gabi Wazz, Tarek Mahdy, Koen Venema

All Works

Background: Growing evidence supports the role of gut microbiota in obesity, yet exact associations remain largely unknown. Specifically, very little is known about this association in the Emirati population. Methods: We explored differences in gut microbiota composition, particularly the Firmicutes/Bacteroidetes (F/B) ratio, between 43 obese and 31 lean adult Emirate counterparts, and its association with obesity markers, by using V3-V4 regions of 16 S ribosomal RNA gene sequencing data. Furthermore, we collected anthropometric and biochemical data. Results: The two major phyla in obese and lean groups were Firmicutes and Bacteroidetes. We observed a significantly lower alpha diversity (Shannon index) in …


The Resilience Of American Indian And Alaska Native Older Adults In The Context Of Major Health Disparities In Cardiovascular Disease, Diabetes, Asthma, And Arthritis: A Narrative Review, Ennis Frank Vaile Jan 2023

The Resilience Of American Indian And Alaska Native Older Adults In The Context Of Major Health Disparities In Cardiovascular Disease, Diabetes, Asthma, And Arthritis: A Narrative Review, Ennis Frank Vaile

Graduate Student Theses, Dissertations, & Professional Papers

Background: Multiple major health disparities have been documented in Indian Country, including cardiovascular disease (Howard et al., 1999), diabetes (Acton et al., 2003), asthma (Mannino et al., 2002), and arthritis (Barbour et al., 2017). Prior research has shown that the prevalence rates of these conditions in American Indians and Alaska Natives (AI/ANs) are among the highest in the United States. Given these health disparities, aging older adults in Indian Country may be especially vulnerable to the development of concurrent negative mental health outcomes, particularly depression (Garrett et al., 2015). Nonetheless, AI/AN older adults continue to age successfully and exhibit substantial …


In The Weeds, Bianca J. Jensen Jan 2023

In The Weeds, Bianca J. Jensen

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.


Influence Of Exercise On Brown, White And Beige Adipocytes, Anna C. Covington Jan 2023

Influence Of Exercise On Brown, White And Beige Adipocytes, Anna C. Covington

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.


Ecosystem Phosphorus Nutrition: A Soil Process Investigation, Alanna Nicole Shaw Jan 2023

Ecosystem Phosphorus Nutrition: A Soil Process Investigation, Alanna Nicole Shaw

Graduate Student Theses, Dissertations, & Professional Papers

Many Earth System Models (ESMs) predict a plant fertilization effect associated with elevated atmospheric carbon dioxide (CO2) concentrations that may increase the capacity of the biosphere to store carbon, stabilizing or even reducing atmospheric CO2 concentrations. This could plausibly mitigate global climate change. However, this effect is only possible in the absence of other limiting factors, such as the availability of nutrients like phosphorus (P). Critical uncertainties remain in our understanding of the soil biogeochemical controls of terrestrial P availability including: the response of soil P recycling rates to global climate warming and extent to which occluded soil P is …


Consumers' Willingness To Pay For An Animal Welfare Food Label, Matthew Gorton, Ching Hua Yeh, Elena Chatzopoulou, John White, Barbara Tocco, Carmen Hubbard, Fiona Hallam Jan 2023

Consumers' Willingness To Pay For An Animal Welfare Food Label, Matthew Gorton, Ching Hua Yeh, Elena Chatzopoulou, John White, Barbara Tocco, Carmen Hubbard, Fiona Hallam

Plymouth Business School

Consumers increasingly rate the ethical dimensions of food production, including animal welfare, as important to them but how these concerns influence their food choices remains unclear. To address this, a Discrete Choice Experiment assesses consumers' willingness to pay for chicken meat. The study aims to understand the effects of food labels (RSPCA Assured and Red Tractor), cause-related marketing campaigns, and price on consumers' willingness to pay. Drawing on a representative sample of 401 British consumers, we estimate a mixed logit model using the hierarchical Bayesian estimation method. The results for the full sample reveal a substantial price premium associated with …


End-Of-Life Care In The Last Three Months Before Death In Older Patients With Cancer In Belgium: A Large Retrospective Cohort Study Using Data Linkage, Victoria Depoorter, Katrijn Vanschoenbeek, Lore Decoster, Geert Silversmit, Philip R. Debruyne, Inge De Groof, Dominique Bron, Frank Cornélis, Sylvie Luce, Christian Focan, Vincent Verschaeve, Gwenaëlle Debugne, Christine Langenaeken, Heidi Van Den Bulck, Jean Charles Goeminne, Wesley Teurfs, Guy Jerusalem, Dirk Schrijvers, Bénédicte Petit, Marika Rasschaert, Jean Philippe Praet, Katherine Vandenborre, Harlinde De Schutter, Koen Milisen, Johan Flamaing, Cindy Kenis, Freija Verdoodt, Hans Wildiers Jan 2023

End-Of-Life Care In The Last Three Months Before Death In Older Patients With Cancer In Belgium: A Large Retrospective Cohort Study Using Data Linkage, Victoria Depoorter, Katrijn Vanschoenbeek, Lore Decoster, Geert Silversmit, Philip R. Debruyne, Inge De Groof, Dominique Bron, Frank Cornélis, Sylvie Luce, Christian Focan, Vincent Verschaeve, Gwenaëlle Debugne, Christine Langenaeken, Heidi Van Den Bulck, Jean Charles Goeminne, Wesley Teurfs, Guy Jerusalem, Dirk Schrijvers, Bénédicte Petit, Marika Rasschaert, Jean Philippe Praet, Katherine Vandenborre, Harlinde De Schutter, Koen Milisen, Johan Flamaing, Cindy Kenis, Freija Verdoodt, Hans Wildiers

School of Nursing and Midwifery

This study aims to describe end-of-life (EOL) care in older patients with cancer and investigate the association between geriatric assessment (GA) results and specialized palliative care (SPC) use. Older patients with a new cancer diagnosis (2009–2015) originally included in a previous multicentric study were selected if they died before the end of follow-up (2019). At the time of cancer diagnosis, patients underwent geriatric screening with Geriatric 8 (G8) followed by GA in case of a G8 score ≤14/17. These data were linked to the cancer registry and healthcare reimbursement data for follow-up. EOL care was assessed in the last three …


Knowledge Sharing And Referral Practices By Traditional Birth Attendants In Low-Income Urban Areas Of Southwest Nigeria, Janet O. Adekannbi, Joy O. Oluwafemi Jan 2023

Knowledge Sharing And Referral Practices By Traditional Birth Attendants In Low-Income Urban Areas Of Southwest Nigeria, Janet O. Adekannbi, Joy O. Oluwafemi

Library Philosophy and Practice (e-journal)

Traditional birth attendants (TBAs) are important for maternal health care especially in Africa’s low-income areas. Without doubt, the relevance of TBAs in developing countries such as Nigeria is not expected to reduce in the foreseeable future. The knowledge of traditional birth attendants will continue to be needed and considering the tacit nature of their knowledge, there is a need to preserve the knowledge in this profession and promote sharing of best practices to prevent maternal mortality issues. This study investigated the knowledge sharing (KS) and referral practices of TBAs in low-income urban areas of South-west Nigeria. Qualitative approach was adopted …