Digital Commons Network^™

Sociocultural Determinants Of Exclusive Breastfeeding And Infant Feeding Practices In Niger, Maimouna Issoufou Kapran

Electronic Theses and Dissertations

Niger is one of the countries with the lowest exclusive breastfeeding (EBF) rates in the world. The purpose of this study was to determine the barriers to EBF in Niger and to determine the types of feedings that are most commonly practiced in Niger. Participants (n=31) were mothers with children aged 0 to 24 months, recruited on-site at a healthcare facility in Niamey, the capital of Niger. They completed a 20-item questionnaire on socio-demographics, breastfeeding support and knowledge, a short food security survey, and a 24-hour diet recall. All mothers interviewed breastfed at some point, and a majority of the …

Analysis Of Dietary Micronutrient Intake Of Ncaa Track And Field Athletes, Haley Noelle Melton

Electronic Theses and Dissertations

Vitamins and minerals play an important role in many functions within the body and contribute to maintenance of health and well-being of all individuals, including athletes. An athlete’s performance could be negatively impacted if micronutrient recommendations are not met consistently. The purpose of this study was to analyze the dietary micronutrient consumption of NCAA Division I Collegiate Track and Field athletes. Thirty-seven track and field athletes, 15 females and 22 males, participated in the study. Multiple 24-hr recalls were collected, including weekdays and weekends, and analyzed using NSDR to obtain average dietary micronutrient intakes, which could then be compared to …

Assessing The Accuracy Of Dental Age Estimation Methods In A Native American Pediatric Sample, Cal Matthew Mcgehee

Electronic Theses and Dissertations

Dental age estimation is a common method used to determine the age of juvenile individuals in forensics, medicine, and bio-archaeology. This thesis examines how accurate three dental development methods are in estimating the ages of two Native American sample groups. Further, it will explore how different variables like sex, age, secular (temporal) change, and an individual’s body mass index (BMI) affect dental development rates in the two groups of individuals. The first group consists of 60 Native Americans between the ages of 7 and 21 years of age who received dental work between 1970-1990 by Dr. James Economides of Albuquerque, …

Fight For Your Life: A Study Of Fairness In The Ultimate Fighting Championship's Anti-Doping Policy Appeals Process, Brandon Hamroff

Cardozo Journal of Conflict Resolution

No abstract provided.

Biological Adaptations Leading To Metastatic Potential In Ovarian Cancer, Hussein Chehade

Wayne State University Dissertations

Ovarian cancer induces most deaths from gynecological cancers. Patients succumb due to heavy metastatic tumor burden, which accounts for 90% of cancer related deaths and is characterized by the dissemination of malignant cells from primary tumor to secondary site(s), partaking in cancer progression. Ovarian cancer progression is an extremely demanding process that requires cancer cells to be able to survive anoikis conditions and be metabolically flexible to survive microenvironmental changes during transit to a secondary site. Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) is a bi-organellar protein primarily present in the mitochondria by which it can prevent apoptosis and/or enhance mitochondrial …

The Urdu-Speaking Community Of Bangladesh: Forgotten Denizens Or Putative Citizens?, Naimul Muquim

Emory International Law Review

The Urdu-speaking community in Bangladesh, commonly known as the “Biharis” or “Stranded Pakistanis,” has been living in distressing circumstances. Despite the Supreme Court of Bangladesh declaring Urdu-speakers citizens of the country in 2008, there continues to be challenges related to their integration prospects. The community still faces widespread discrimination, primarily because of the Bangladeshi bureaucracy’s systemic neglect and the community’s former refugee and stateless status. This study examines to what extent Urdu-speakers are now able to enjoy full citizenship rights. It also assesses the government of Bangladesh’s existing policies and the relationship between citizenship and the law, comprising of both …

Goals And Proceedings Information, William S. Walker Iii, Lynn A. Bryan Ph. D., S. Selcen Guzey, Elizabeth Suazo-Flores

Indiana STEM Education Conference

No abstract provided.

Engaging Students And Teaching Life Skills Through Community Collaboration, Kim Stein

Language Arts Journal of Michigan

Collaboration with the Youth First Program of Saginaw increased students' engagement in eleventh-grade English. Students bonded with community partners, their teacher, and their peers in new ways which produced an environment of mutual respect and deeper learning. Students engaged in a debate project which garnered recognition from school administrators and community members, who were influenced to enact positive changes for the school community.

The Impact Of Single-Gendered Versus Coeducational Physical Education Settings On Female Adolescent Body Image And Self-Esteem: Resisting The Weight Of Body Image And Self-Esteem Issues In Adolescence, Jamison H. Stockslager

EWU Masters Thesis Collection

Resistance training is related to disease prevention, improved health, and positive psychosocial well-being in adults and adolescents. Further, resistance training is positively associated with body image and self-esteem. However, most adolescents do not meet activity guidelines, particularly for resistance training. Schools play an essential role for increasing physical activity. Little is known about the effects of different classroom formats for resistance training, i.e., single-gendered versus coeducational, on body image and self-esteem in female adolescents.

PURPOSE: To determine the effects of single-gendered versus coeducational resistance training on body image and self-esteem in adolescent females. METHODS: High school females (n = 30) …

The Physiological And Psychological Performance Effects Of Multi-Ingredient Pre-Workout Supplements In Females During Resistance Training, Mariah L. Snyder

EWU Masters Thesis Collection

In recent years, the use of supplements to aid resistance training performance has increased, particularly through the consumption of multi-ingredient pre-workout supplements (MIPS). However, limited research exists regarding the efficacy of MIPS on physiological and psychological performance in resistance-trained females.

PURPOSE: To determine the physiological and psychological performance effects of MIPS compared to a placebo and caffeine-only supplement in resistance-trained females.

METHODS: Resistance-trained females (n=10) volunteered for the study. One-repetition maximum (1RM) was established at baseline for leg press (LP) and bench press (BP). A within-groups, double-blind, randomized, and counterbalanced design was used to assign the four supplement drinks (i.e., …

An Evaluation Of A Health, Wellbeing And Lifestyle Promotion Intervention Among A Cohort Of Year 1 Male Gaelic Games Student Athletes In An Irish University Setting, Anthony Casey

Theses

Background: The current research investigated the health, wellbeing and lifestyle behaviours of a cohort of 1st year male Gaelic Games student athletes (Study 1), and subsequently evaluated the impact of a bespoke intervention on these health, wellbeing and lifestyle behaviours in the same cohort (Study 2).

Methods: Participants were 1st year male Gaelic Games student athletes (mean age 18.6 ± 0.6 years, n=166) in a university in southern Ireland. Data were collected using a mixed-methods approach during the 2018/19 and the 2019/20 academic years. Data collection consisted of an online questionnaire (Bickerdike et al., 2018), which assessed health, wellbeing …

Exploring The Metabolic Capabilities And Biotransformation Potential Of Environmental Lactococcus Strains, Desirée Román Naranjo

Theses

The aim of this thesis is to characterize environmental Lactococcus strains to identify different and diverse metabolic capabilities that could be applied to microbial biotransformation, defined as the conversion of a cheap/waste substrate into a value-added product. Due to the increased amounts of food processing waste generated worldwide and the impact of climate change, new sustainable approaches are necessary to contribute to waste valorization and the circular bioeconomy. We ask to what extent and in what ways environment isolated Lactococcus strains could contribute to food biotransformation by metabolizing a different range of substrates. We do so to further understand and …

‘A Healthy Mtu’ A Mixed Methods Baseline Programme Of Research To Empirically Inform A Campus Health Promotion Initiative Within An Irish Higher Education Setting, Andrea Bickerdike

Theses

Higher Education Institutions (HEIs) have been called to lead global health promotion actions, yet there remains a dearth of empirically informed ‘Healthy University’ (HU) initiatives. This thesis constituted a baseline mixed methods needs assessment to inform a settings-based health promotion (HP) initiative (‘A Healthy MTU’) within a multi-campus ‘case’ HEI in Ireland (Cork campuses of MTU, formerly CIT). Specific aims were to (i) investigate student and staff health metrics, and (ii) identify the cultural and environmental determinants of health and wellbeing within the case HEI setting. Using a phased, mixed methodology (QUAN-QUAL), five sequential empirical studies were undertaken. Quantitative data …

Investigating Optimal Lipid:Protein Profiles For Infant Milk Formula, Valentina Ivanova

Theses

From the early twentieth century onward, much research has focused on improving infant milk formula (IMF). During the development of IMF, breast milk is commonly considered as the reference and IMF manufacturers are thriving to mimic the composition and/or to match the functionality of breast milk as closely as possible. A variety of bioactive ingredients, found in human breast milk, have been isolated and investigated for their potential functionality and utilised in the production of IMF. This study evaluated the current knowledge on compositional differences between human breast milk and IMF, and recent advances and developments in IMF production. Following …

Isolation And Characterisation Of Soil-Derived Bacteria With Antimicrobial Activity Against Antibiotic Resistant Pathogens, Ellen Twomey

Theses

Bacteriocins are a diverse range of ribosomally synthesized bioactive peptides, recognised predominantly for their potent antimicrobial activity against other strains closely related to the producer. The focus of this thesis was to explore this activity and examine the potential of bacteriocins to inhibit the growth of clinically relevant pathogens. Although evidence exists in the literature to suggest that bacteriocins could be applied in a similar fashion to conventional antibiotics, to date they are only utilised as preservative in food to prevent the growth of foodborne illness causing organisms. Isolating and screening bacterial strains in order to identify bacteriocin producers has …

An Evaluation Of The Psychosocial Benefits For Children Experiencing Homelessness Arising From The Introduction Of An Integrated Community Care Project Across The City Of Cork, Traolach O' Callaghan

Theses

The purpose of the research is to evaluate an intervention within a new model of family support being delivered in Cork City, on addressing child and family homelessness. This new model is being delivered for the first time in Ireland during ‘Youth Club’ and strives to act as an intervention to assist children experiencing homelessness. The model was first developed by Tusla Springboard Child and Family service and Good Shepherd Services Cork in 2016 in response to the alarming rise in child and family homelessness in Cork city, and the resulting impact of same. The research investigates the model and …

The Use Of Membrane Filtration To Increase Native Whey Protein In Infant Formula, And Effects On Bioaccessibility And Bioactivity, Yihong Chen

Theses

Breastfeeding is recognised as the gold standard for feeding newborns and infants. However, infants who cannot be breast-fed or for whom breast milk is not available, can be fed with bovine infant milk formula (IMF) as a substitute. Researchers and producers of IMF strive to continually improve or “humanise” the composition and functionality of IMF. During production of IMF it must undergo several heat treatment steps, e.g. heat-sterilisation or spray-drying, in order to provide a safe product to the infant. These heat treatments denature the globular whey proteins in IMF. In contrast, breast milk is by its nature unheated, so …

Alzheimer’S Disease (Ad) Knowledge In Korean Americans: Identifying Knowledge Gaps And Misconceptions And Examining Predictors Of Ad Knowledge, Sang E. Lee, Michin Hong, Banghwa L. Casado

Faculty Research, Scholarly, and Creative Activity

Objectives: This study examined Alzheimer’s disease (AD) knowledge and its predictors among Korean Americans (KAs). Design: Convenience sampling was used to recruit KAs in the Greater Washington metropolitan area. A total of 268 KAs participated in the study and completed a cross-sectional survey in 2014. Using the Alzheimer’s Disease Knowledge Scale (ADKS), overall and domain knowledge was assessed. Multiple regression analyses were conducted for overall and domain knowledge with predictors including exposure to AD, social engagement, sources and frequency of health-related information, stigmatic beliefs (pity, antipathy, and social distance), English proficiency, and education. Results: KAs reported a 59% accuracy in …

Gene-Educational Attainment Interactions In A Multi-Population Genome-Wide Meta-Analysis Identify Novel Lipid Loci, Lisa De Las Fuentes, Karen L. Schwander, Yun Ju Sung, Mary F. Feitosa, Ahn Do, C. Charles Gu, Treva K. Rice, Mary K. Wojczynski, Michael M. Province, Dabeeru C. Rao, Et Al.

2020-Current year OA Pubs

No abstract provided.

Optimization Of The Modular Reinforced Bone Scaffold For Customized Alveolar Bone Defects, Meisam Omidi, Luis Eduardo Almeida, Lobat Tayebi

School of Dentistry Faculty Research and Publications

A modular reinforced bone scaffold with enhanced mechanical properties has recently been developed by our group. It includes: 1) A load-bearing module: a skeleton which is made of a slowly degradable material, undertaking mechanical necessities of the scaffold, and 2) A bio-reactive module: a porous and biodegradable component undertaking biological necessities of the scaffold. The load-bearing module is placed into the bio-reactive module to reinforce it. This paper is dedicated to optimizing the load-bearing module for a certain customized alveolar bone defect. More specifically, a 3D-printed skeleton, made of polycaprolactone (PCL), is optimized based on the boundary conditions of the …

Creating A Primary Care Track In Prelicensure Nursing Education, Janice E. Hawkins, Lynn L. Wiles, Jamela Martin, Beth Tremblay, Karen Higgins, Ingrid Mahoney

Ellmer School of Nursing Faculty Publications

BACKGROUND: RNs practicing in primary care (PC) increase access to health care and contribute to better patient outcomes and cost savings, yet undergraduate nursing education traditionally focuses on disease-oriented care. This article describes a curricular track for infusing PC prelicensure programs.

METHOD: PC content is threaded across four semesters with targeted assignments and clinical experiences. Providing clinical immersion experiences with practicing RNs as preceptors in community and PC settings is a key component of this initiative.

RESULTS: Student feedback has been favorable. Students stated they gained insight to the role of RNs in PC through class assignments and clinical rotations. …

Nonalcoholic Fatty Liver Disease Is A Risk Factor For Thiopurine Hepatotoxicity In Crohn's Disease, Alvin T George, Matthew Glover, Quazim Alayo, Maria Zulfiqar, Daniel R Ludwig, Matthew A Ciorba, Scott Mchenry, Parakkal Deepak

2020-Current year OA Pubs

BACKGROUND: Patients with Crohn's disease (CD) are predisposed to nonalcoholic fatty liver disease (NAFLD). CD management often includes thiopurines which can promote hepatotoxicity. We aimed to identify the role of NAFLD on the risk of developing liver injury from thiopurines in CD.

METHODS: In this prospective cohort analysis, CD patients at a single center were recruited 6/2017-5/2018. Patients with alternative liver diseases were excluded. The primary outcome was time to elevation of liver enzymes. Patients underwent MRI with assessment of proton density fat fraction (PDFF) on enrollment, where NAFLD was defined as PDFF >5.5%. Statistical analysis was performed using a …

Training In Eight Low-And Middle-Income Countries: Lessons Learned From A Pilot Study Using The Who-Tdr Dissemination And Implementation Massive Open Online Course, Ashlin Rakhra, Victor Davila-Roman, Ana A Baumann, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Non-communicable diseases (NCDs) are a leading cause of morbidity and mortality in low-and middle- income countries (LMICs). Despite this, a lack of funding, training and mentorship for NCD investigators in LMICs exists. In an effort to gain knowledge and skills to address these gaps, participants from the Global Research on Implementation and Translation Science (GRIT), a consortium of studies in eight LMICs and their networks, attended the dissemination and implementation (D&I) massive open online course (MOOC) developed by the Special Programme for Research and Training in Tropical Diseases at the World Health Organization to strengthen D&I capacity building. Here, …

Advancing College Food Security: Priority Research Gaps, Matthew J. Landry, Emily Heying, Zubaida Qamar, Rebecca L. Hagedorn-Hatfield, Mateja R. Savoie-Roskos, Cara L. Cuite, Victoria A. Zigmont, Kendra Oonorasak, Susan Chen

Faculty Research, Scholarly, and Creative Activity

Despite over a decade of both quantitative and qualitative studies, food insecurity among United States college/university students remains a pervasive problem within higher education. The purpose of this perspective piece was to highlight research gaps in the area of college food insecurity and provide rationale for the research community to focus on these gaps going forward. A group of food insecurity researchers from a variety of higher education institutions across the United States identified five thematic areas of research gaps: screening and estimates of food insecurity; longitudinal changes in food insecurity; impact of food insecurity on broader health and academic …

Shifting Mediates Gendered Racial Microaggressions And Perceived Racism Among Asian American Women, Glenn Gamst, Christine Ma-Kellams, Lawrence S. Meyers, Leticia Arellano-Morales

Faculty Research, Scholarly, and Creative Activity

Introduction: Microaggressive attacks on Asian American women increased during the COVID-19 pandemic. The present study tested whether Asian American women's shifting, a coping strategy employed by some women of color to alter their self-presentation in response to perceived racism, mediated the association between gendered racial microaggressions and self-perceived subtle and blatant racism. Methods: A convenience sample of 253 Asian American adult women completed the gendered racial microaggressions scale for Asian American women (GRMSAAW), the Asian American women's shifting scale (AsAWSS), and the subtle and blatant racism scale for Asian American college students (SABR-A2). Results: Results from a structural equation model …

Composition, Nutritional And Physicochemical Properties Of Milk Fat Globule Membrane Enriched Ingredients For Use In Infant Nutrition Products, Pierre Ponchon

Theses

The aim of this thesis was to investigate the nutritional, techno-functional and physicochemical properties of milk fat globule membrane (MFGM) enriched whey protein concentrate (WPC) ingredients. This research focused on the physicochemical, nutritional, techno-functional, and microstructural properties of MFGM-enriched whey protein concentrate (WPC) powder ingredients, which included 3 MFGM-enriched WPC ingredients and a WPC ingredient co-enriched with α-lactalbumin and MFGM. These were compared to parallel stream (WPC 80 and whey protein isolate (WPI)) and upstream, whole milk powder (WMP) bovine derived ingredients of varying macromolecular composition, including MFGM-enrichment. The macromolecular compositions of the MFGM-enriched WPC ingredients included fat contents ranging …

An Investigation Into The Irish Bread Market With A Particular Focus On Sourdough Bread. Are Increased Numbers Of Consumers Purchasing Sourdough Bread? If So, Why And What Do They Know About It?, Aisling Kelly

Theses

Bread has a long-standing history in the Irish diet and remains a staple part of our calorie intake with an average consumption of 37.5 kg per person per annum (Jocelyn, 2020; Murtagh, 2009). While the traditional breads of oatcakes and soda bread have remained a favourite for many decades, Ireland’s bread market has also evolved to include baked items from all over the world. Most recently, consumers have altered their purchasing habits in relation to bread due to the enforced restrictions on the movement of people (and consequently goods) during the COVID-19 pandemic of 2020 to 2022. Evidence suggests that …

An Overview: The Diversified Role Of Mitochondria In Cancer Metabolism, Yu'e Liu, Yihong Sun, Yadong Guo, Xiaoyun Shi, Xi Chen, Wenfeng Feng, Lei-Lei Wu, Jin Zhang, Shibo Yu, Yi Wang, Yufeng Shi

Faculty, Staff and Students Publications

Mitochondria are intracellular organelles involved in energy production, cell metabolism and cell signaling. They are essential not only in the process of ATP synthesis, lipid metabolism and nucleic acid metabolism, but also in tumor development and metastasis. Mutations in mtDNA are commonly found in cancer cells to promote the rewiring of bioenergetics and biosynthesis, various metabolites especially oncometabolites in mitochondria regulate tumor metabolism and progression. And mutation of enzymes in the TCA cycle leads to the unusual accumulation of certain metabolites and oncometabolites. Mitochondria have been demonstrated as the target for cancer treatment. Cancer cells rely on two main energy …

Microrna-1 Attenuates The Growth And Metastasis Of Small Cell Lung Cancer Through Cxcr4/Foxm1/Rrm2 Axis, Parvez Khan, Jawed A. Siddiqui, Prakash Kshirsagar Dr., Ramakanth Chirravuri Venkata, Shailendra K. Maurya, Tamara Mirzapoiazova, Naveenkumar Perumal, Sanjib Chaudhary, Ranjana K. Kanchan, Mahek Fatima, Md Arafat Khan, Asad Ur Rehman, Imayavaramban Lakshmanan, Sidharth Mahapatra, Geoffrey A. Talmon, Prakash Kulkarni, Apar Kishor Ganti, Maneesh Jain, Ravi Salgia, Surinder K. Batra, Mohd W. Nasser

Journal Articles: Biochemistry & Molecular Biology

BACKGROUND: Small cell lung cancer (SCLC) is an aggressive lung cancer subtype that is associated with high recurrence and poor prognosis. Due to lack of potential drug targets, SCLC patients have few therapeutic options. MicroRNAs (miRNAs) provide an interesting repertoire of therapeutic molecules; however, the identification of miRNAs regulating SCLC growth and metastasis and their precise regulatory mechanisms are not well understood.

METHODS: To identify novel miRNAs regulating SCLC, we performed miRNA-sequencing from donor/patient serum samples and analyzed the bulk RNA-sequencing data from the tumors of SCLC patients. Further, we developed a nanotechnology-based, highly sensitive method to detect microRNA-1 (miR-1, …

Characteristics Of Type 2 Diabetes In Female And Male Youth, Beatriz Castillo Rodriguez, Marcela Astudillo, Mustafa Tosur, Ahmad Rafaey, Siripoom Mckay, Fida Bacha, Ashok Balasubramanyam, Maria J Redondo

Faculty, Staff and Students Publications

The incidence of type 2 diabetes in children is rising and carries a worse prognosis than in adults. The influence of sex on pediatric type 2 diabetes outcomes has not been well investigated. We studied 715 youth with type 2 diabetes diagnosed at a median age of 13.7 years and compared sex differences in demographic, clinical, and laboratory characteristics within the first year of diagnosis. Females diagnosed with type 2 diabetes were younger and at a higher stage of pubertal development than males, yet presented with lower A1Cs, a lower prevalence of diabetic ketoacidosis, and higher HDL cholesterol levels.