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Sdf-1 Induces Directional Chemotaxis Of Endogenous Bmscs At The Intervertebral Fusion Site And Promotes Osteogenic Differentiation By Regulating Wnt/Ss-Catenin In The Bone Marrow Chimera Spinal Intervertebral Fusion Mouse Model, Qiwen Zhang, Ning Liang, Bin He, Siyou Wu, Depeng Wen, Xiaoyong Tang, Xiongcheng Shen

Turkish Journal of Biology

Clinical observations show that the current spinal fusion with internal fixation has a nonfusion rate of 5%-35%; however, methods to promote spinal fusion are limited. This study aimed to investigate the role of SDF-1-induced directional chemotaxis of BMSCs in bone marrow chimera spinal intervertebral fusion mouse model. BMSCs were isolated from bone marrow and identified by detecting CD44/CD34 positive cells. BMSCs (GFP-BMSCs) were labeled with GFP for tracking in vivo. Mice were inoculated with GFP-BMSCs to construct bone marrow chimera spinal intervertebral fusion model, which were divided into BM-SIF model, BM-SIF+SDF-1, BM-SIF+SDF-1-Anta group. The callus area of intervertebral fusion site …

Methionine Restriction And Cancer Treatment: A Systems Biology Study Of Yeast To Investigate The Possible Key Players, Esra Börklü

Turkish Journal of Biology

Background/aim: Dietary restriction, mainly carbon and/or methionine restriction are among the upcoming supporting interventions along with chemotherapy in various cancers. Although dietary restriction has been proven to be beneficial, the main cellular machineries affected by its administration lacks deeper information considerably, a notable pitfall in its use as a personalized nutritional approach. Materials and methods: In this study, cellular effects of methionine restriction on a yeast model are explored via systems biology approaches. The methionine biosynthesis network, constructed by integrating interaction data with gene ontology terms, was analysed topologically, and proved to be informative about the intertwined relationship of methionine …

Adolescent Education, Health And Wellbeing Status In Four Counties In Kenya: Two Years Into The Covid-19 Pandemic, Population Council Kenya

Adolescents and Young People

The COVID-19 pandemic resulted in widespread school closures globally, including in Kenya. This educational disruption had potential adverse consequences for adolescent school learners including school dropout, learning loss, opportunity losses, loss of previously acquired skills, and loss of socio-emotional benefits of time spent with peers and teachers. This study was undertaken in four counties in Kenya—two urban (Nairobi, Kisumu) and two rural (Kilifi and Wajir). Focusing on adolescent girls aged 10–19, the study increased understanding of the impact of the COVID-19 pandemic on girls’ education outcomes to enable implementation of policies and programs to address immediate harms caused, and to …

Remnants Of Caste: Black Farmers, White Farmers, Congress, And The Usda, Kathryn Fitzgerald

University of Maryland Law Journal of Race, Religion, Gender and Class

No abstract provided.

Synthesis And Characterization Of Soybean Feedstock-Based Composite Systems For Sustainable Material Application., Temofeh Nathaniel Esenamunjor

Theses and Dissertations

This study explores the synthesis and characterization of soybean-based composites with a focus on their potential for sustainable material applications. Soybean meal (SBM), known for its high protein content, is blended with the biopolymer polylactic acid (PLA) using eco-friendly manufacturing processes. The solvent casting and hot-pressing methods are employed to fabricate composites, and their mechanical and thermal properties are investigated. Tensile strength of the composites decreases with higher concentrations of soybean meal, while thermal properties remain comparable to PLA. The hot press method, optimized at 250°C and 235 MPa, shows promising results in enhancing compressive strength with increased SBM concentration …

Exploring The Perception Of Patients, Providers, And Healthcare Leaders Of The 15-20 Minute Primary Care Visit, Zuhur Hassan Ahmed

Walden Dissertations and Doctoral Studies

While primary care plays a vital role in health maintenance and disease prevention, patients’ visits with primary care providers (PCP) are only 15-20 minutes on average. This visit length does not leave ample time for holistic care for patients with low socioeconomic backgrounds, who might also have psychosocial issues alongside their chronic conditions. Employing a qualitative multiple case study research design, this study explored participants' perceptions about the 15–20-minute visit duration with PCPs. Guided by the triple aim framework of improving patient healthcare outcomes, patient satisfaction with care, and cost of care per capita, this study answered the research question …

Experiences With Access To Seeking And Maintaining Home Health Care Services In Low-Income Communities, Staci Yvette Kennedy

Walden Dissertations and Doctoral Studies

AbstractHome health care services (HHCS) are a cost-effective service option often underutilized by individuals living in low-income communities. For this population, barriers to care may result in higher health care costs and poor health outcomes. Gaps in literature indicated a need to explore experiences of accessing and maintaining home health care among individuals living in low-income communities. The purpose of this qualitative research study was to gain insight into how individuals living in low-income communities perceive their access to HHCS. The conceptual framework used for this phenomenological study was Penchansky and Thomas’s model of access, which addresses access from seven …

Stroke Survivors’ And Informal Caregivers’ Perceptions Of Depressive Symptoms After Stroke: A Mixed-Methods Sequential Explanatory Study, Tanya Leigh Breckenridge-Trotter

Theses and Dissertations

Background: Poststroke depression (PSD) is a frequently occurring complication of stroke that affects up to 30% of all stroke survivors in the first 24 months after stroke. PSD has been correlated with increases in hospital length of stay and hospital costs, increased physical morbidity and mortality, the risk for recurrent stroke at one year, decreased functional outcome, decreased cognitive function, and decreased quality of life post stroke. Estimates are >50% stroke survivors with depressive symptoms are left untreated due to lack of recognition. Moreover, depression in family caregivers of stroke survivors may negatively influence stroke recovery and stroke survivor quality …

Self-Efficacy Of Applied Doctoral Students Scale: Initial Development And Validation, Kylie Anne George

Theses and Dissertations

The present study explored the development and initial validation of a measure of doctoral student self-efficacy for students in Health Profession Training (HPT) programs. There is a gap in existing scales that measure the full spectrum of tasks that contribute to doctoral self-efficacy. The scales that do exist focus on broad self-efficacy (Chen et al., 2001) or program-specific self-efficacy in one area (Stump et al., 2012; Van Horn & Christman, 2017; Lent et al., 2003). Our purpose was to develop and provide initial norming and validity information for the Self-Efficacy of Applied Doctoral Students (SEADS) Scale. The SEADS was developed …

Cognitive Decay And Memory Recall During Long Duration Spaceflight, Terry E. Rector

Theses and Dissertations

This dissertation aims to advance the efficacy of Long-Duration Space Flight (LDSF) pre-flight and in-flight training programs, acknowledging existing knowledge gaps in NASA's methodologies. The research's objective is to optimize the cognitive workload of LDSF crew members, enhance their neurocognitive functionality, and provide more meaningful work experiences, particularly for Mars missions.The study addresses identified shortcomings in current training and learning strategies and simulation-based training systems, focusing on areas requiring quantitative measures for astronaut proficiency and training effectiveness assessment. The project centers on understanding cognitive decay and memory loss under LDSF-related stressors, seeking to establish when such cognitive decline exceeds acceptable …

The Effects Of Demographic And Nutritional Variables On Anxiety And Depression Symptoms In Usa And Non-Usa Adults, Jonathan Santiago

Theses and Dissertations

The present study investigated the effects of demographic variables (e.g. country of residence and socioeconomic status) and nutritional variables (e.g. dietary diversity and micronutrient content) on anxiety and depression symptoms, as well as subjective health self-rating. Prior research suggests that a variety of demographic and nutritional factors influence chronic stress, which can cause systemic inflammation and lead to various cardiovascular-related diseases. Participants (USA=41; Non-USA= 58) were recruited via an online platform and completed demographic questionnaires and a 24-hour dietary recall. Results indicated that food accessibility emerged as the strongest predictor, and was associated with anxiety, depression, and combined mood symptoms. …

Exploring The Perception Of Patients, Providers, And Healthcare Leaders Of The 15-20 Minute Primary Care Visit, Zuhur Hassan Ahmed

Walden Dissertations and Doctoral Studies

While primary care plays a vital role in health maintenance and disease prevention, patients’ visits with primary care providers (PCP) are only 15-20 minutes on average. This visit length does not leave ample time for holistic care for patients with low socioeconomic backgrounds, who might also have psychosocial issues alongside their chronic conditions. Employing a qualitative multiple case study research design, this study explored participants' perceptions about the 15–20-minute visit duration with PCPs. Guided by the triple aim framework of improving patient healthcare outcomes, patient satisfaction with care, and cost of care per capita, this study answered the research question …

The Association Between Working Habits And Hypertension Among First Generation African Immigrants, Olalekan Kilo

Walden Dissertations and Doctoral Studies

Even though hypertension affects people of all races, it is more prevalent among African Americans. However, recent research has revealed that the prevalence of hypertension is progressively increasing across Africa. African immigrants in the United States are the least-studied immigrant group prone to health inequalities when compared to their African American counterparts. To help bridge this gap, a secondary data analysis of a cross-sectional study was conducted to investigate the association between working habits (hours worked, diet at work), length of stay in the United States, and hypertension rates for first-generation African immigrants residing in the United States. The study …

Theoretical Orientation Beliefs Among Adventure Therapy Professionals, Edward Spaulding

Walden Dissertations and Doctoral Studies

Adventure therapy as a therapeutic model for the treatment of mental health has been a growing area of psychology for more than 50 years. This quantitative study was conducted to explore the theoretical orientation beliefs to clarify the theoretical framework of this therapeutic approach using Coleman’s theoretical evaluation self-test (TEST) to gather data on self-identified adventure therapy practitioners’ theoretical beliefs. Data were collected from 150 participants recruited through their membership or affiliation with adventure therapy professional organizations or social media groups. Data were analyzed using a paired t-test to determine if adventure therapy professionals have higher scores on the cognitive, …

Occupational Stress Of Adult Protective Service Workers, Tiffany Taylor

Walden Dissertations and Doctoral Studies

Research has revealed that adult protective service workers experience high levels of occupational stress that often result in health complications such as burnout, secondary traumatic stress, and compassion fatigue. Although several qualitative studies have been conducted over the past decade, there was limited information on the phenomenon of how stress is experienced by adult protective service workers investigating cases of alleged elder abuse. The purpose of this study was to examine the lived experiences of a sample of adult protective service caseworkers from the southwestern United States that have experienced occupational stress while investigating cases of elder abuse. This study …

Experiences Of Older Adults With Hiv/Aids Enrolled In Case Management Programs In Northwest Indiana, Antoinette Cardenas

Walden Dissertations and Doctoral Studies

AbstractIn 2016, more than half of those infected with HIV/AIDS were age 50 years or older. Since the introduction of antiretroviral therapy, the survival rate of HIV patients has been on the rise with a predicted increase by 2030, but this has also contributed to early onset of comorbidities such as cardiovascular disease, osteoporosis, and kidney failure. The purpose of this generic qualitative study, driven by ecological systems theory, was to explore the experiences of older adults (age 50 and older) with HIV/AIDS who were enrolled in case management programs in Northwest Indiana. Data were collected from semi structured interviews …

Pregnancy Advance Directives, Joan H. Krause

Faculty Publications

Part I of this Article provides a general introduction to the various types of advance directives available in the United States, including their goals and limitations. Part II provides a detailed overview of pregnancy restrictions, including comparisons of the substantive restrictions, procedural issues, and rationales for restricting the application of advance directives during pregnancy. Part III offers a critical analysis of both the scholarship addressing pregnancy restrictions and the litigation seeking to challenge the restrictions, demonstrating that the existing legal framework has not been satisfactory in resolving the issues—a situation that will only be exacerbated by the Supreme Court’s recent …

Sorting Bugs And Features Of Mass Tort Bankruptcy, Melissa B. Jacoby

Faculty Publications

In 1997, after two years of study, the National Bankruptcy Review Commission recognized bankruptcy’s potential as a forum to address mass tort problems. It emphasized, however, that Congress needed to do much more to ensure due process, address major risks of under-compensation and inconsistent compensation, and reduce uncertainty about the lawfulness of these cases. United States Supreme Court cases invalidating particular limited-fund class actions raised the stakes, casting doubt on certain analogous bankruptcy practices.

Congress adopted neither the Commission’s proposals nor others on the topic. Mass tort bankruptcy practice continued without legislative clarifications or improvements, culminating in recent high-profile and …

Boost Your Brain And Memory Flyer, Michele Kroll

UNH Cooperative Extension

No abstract provided.

Diets Of Invasive Channel Catfish Are Subsidized By Invasive Riparian Trees, Christopher A. Cheek, Brandon K. Peoples, Reuben R. Goforth

Natural Resource Management Faculty Publications

Russian olive (Elaeagnus angustifolia) is an invasive, fruit- bearing riparian tree that dominates riparian zones of the San Juan River in the southwestern United States. Previous research in this river suggests olive fruit is common in diets of invasive channel catfish (Ictalurus punctatus), but its energetic importance is unknown (i.e. critical for catfish fitness vs. incidental consumption). We assessed Russian olive consumption in channel catfish diets bimonthly for 1 year, hypothesizing that olive consumption would be greatest during periods of high olive availability and low benthic aquatic invertebrate availability. We found that catfish consumed olive fruit throughout the year and …

Facing Into The Blizzard: Resiliency And Mortality Of Native And Domestic North American Ungulates To Extreme Weather Events, Jeff Martin

Natural Resource Management Faculty Publications

Unseasonably early blizzards in the northern Great Plains threaten large mammal populations unacclimated for variable and extreme winter conditions. This region averaged 22 blizzards per winter season during the 2010s, up from 6 during the 1960s, and is anticipated to average 32 blizzards by the 2050s. In early October 2013, the fatal Atlas Blizzard affected four livestock and captive species in 16 counties of western South Dakota. Expected one-week total death losses for the study area were estimated from national average background mortality rates: 161 cattle, 102 sheep, 9 horses, and 6 bison. However, observed death loss varied significantly (McNemar’s …

Wild Foods Contribute To Women’S Higher Dietary 1 Diversity In India, Jennifer Zavaleta Cheek, Nathalie J. Lambrecht, Bowy Den Braber, Nirali Akanchha, Dhanapal Govindarajulu, Laura Vang Rasmussen

Natural Resource Management Faculty Publications

Wild foods, from forests and common lands, can contribute to food and nutrition 32 security. Most previous studies have established correlations between wild food 33 consumption and children’s dietary diversity in Africa, but other groups and geographic 34 contexts remain understudied. Here, a rigorous quasi-experimental method was 35 combined with monthly-interval data to assess the contribution of wild foods to women’s 36 diets. We collected 24-hour diet recall data monthly, from November 2016 to November 37 2017, from 570 households in East India. We found that wild foods contributed 38 positively to diets, especially in June and July (when consumption …

The Encyclopedia Of Neutrosophic Researchers, Vol. 6, Florentin Smarandache, Maikel Yelandi Leyva Vázquez, Jesús Estupiñán Ricardo

Branch Mathematics and Statistics Faculty and Staff Publications

Este es el Sexto volumen de la Enciclopedia de Investigadores Neutróficos, editados a partir de materiales ofrecidos por los autores que respondieron a la invitación del editor. Los autores se enumeran alfabéticamente. La introducción contiene una breve historia de la neutrosófica, y en especial se sus impacto en latinoamérica junto con enlaces a los principales artículos y libros. Conjunto neutrosófico, lógica neutrosófica, probabilidad neutrosófica, estadística neutrosófica, medida neutrosófica, precálculo neutrosófico, cálculo neutrosófico, psicología neutrosófica, sociología neutrosófica etc., están ganando una atención significativa en resolver muchos problemas de la vida real que implican incertidumbre, imprecisión, vaguedad, incompletitud, inconsistencia e indeterminación. En …

Effectiveness Of Management Program Of Chronic Functional Constipation In Children Who Are Attending The Pediatric Gastroenterology Clinic At Elbeheira Specialized Children's Hospital, Hamouda E. El-Gazzar, Sabreen Ahmed Ali Elsaka, Eman Adel Elsaid Elhaddad

Journal of Medicine in Scientific Research

Background: A chronic constipation is one of the most common functional gastrointestinal complaints in pediatric outpatient clinics. The prevalence of childhood constipation in the general population ranges widely from 0.7% to 29.6% internationally. Pediatric Gastroenterology Clinic at Elbeheira specialized children's Hospital is a referral center from the whole governorate. Objectives: To evaluate the current approach to management, risk factors associated, and clinical characteristics, the challenge of functional constipation in the pediatrics who are attending the Pediatric Gastroenterology Clinic at Elbeheira Specialized Children's Hospital. Methods: This retrospective study was conducted in Pediatric Gastroenterology Clinic at Elbeheira Children's Specialized Hospital for 6 …

Prevalence Of Upper Limb Musculoskeletal Abnormalities In Type 2 Diabetic Patients And Its Relation To Glycemic Control And Associated Factors, Eslam Elsayed Ali Shohda, Amal Emam El-Maghraby, Hadeer Khaled Youssef Elhamid

Journal of Medicine in Scientific Research

Aim of the study: to investigate the prevalence of upper limb musculoskeletal abnormalities and their correlations to glycemic control and associated factors. Methods: A cross-sectional study was conducted at diabetes unit and internal medicine outpatient clinic at Al-ahrar teaching hospital, Zagazig, Egypt. 200 type 2 diabetic patient (T2DM) and 200 non-diabetic control patients of ages > 18 years were enrolled. Rheumatological diseases were excluded. Studied upper limb musculoskeletal abnormalities were Limited joint mobility (LJM), Dupuytren’s contracture (DC), Trigger finger (TF), De Quervain’s tenosynovitis (DQT), Lateral epicondylitis (LE), Medial epicondylitis (ME), Rotator’s cuff tendinitis (RCT) and Carpel tunnel syndrome susceptibility diagnosed by …

Assessment Of Carotid Intima-Media Thickness And Its Relation To Cardiovascular Risk Factors In Obese Children, Faten A.A. Fathi, Somaya M. Abd El Ghany, Ahmed A.H. Taha, Gihan F.A. Hassan, Eman Fouad

Journal of Medicine in Scientific Research

Background Childhood obesity is one of the most critical public health problems today. This study aims to assess the relation between carotid intima-media thickness (CIMT) and cardiovascular risk factors in obese children. Patients and methods This is a case–control study conducted on 80 Egyptian children aged 6–18 years; 40 children with simple obesity as defined by WHO (2011) and 40 healthy children age matched and sex matched were taken as a control group. Cases were selected from the National Nutritional Institute randomly from December 2017 to March 2018. All patients and control groups were subjected to the following: full history …

Assessing Serum Ferritin Together With Some Inflammatory Biomarkers In Overweight And Obese Hospital Care Workers At Elgalaa Teaching Hospital And Its Correlation With Metabolic Syndrome, Sahar Mohamed Said Elbayoumi, Hanan Farouk, Heba Abdelaziz

Journal of Medicine in Scientific Research

Obesity is known to be associated with elevated levels of inflammatory markers. One of the major problems associated with morbidity and mortality. The aim of the study was to assess the posing effect of obesity on the levels of serum ferritin, total cholesterol, HDL and LDL, triglycerides, HBA1C, CRP, and Uric acid with CBC, on random well-being colleague females. Patient and methods: 100 adult female health workers were categorized into three entities according to both BMI and waist circumference, as normal, overweight, and obese. Results: increased serum ferritin as an inflammatory marker might correlate to BMI, in juniors; and might …

Non-Pharmaceutical Symptom Management In Patients With Pcos, Allison Stern

Capstone Showcase

Polycystic Ovarian Syndrome (PCOS) is a relatively common diagnosis among biological females. There are many variations of presentations among patients with PCOS that require an individualized and tailored treatment plan for symptom management. Although there are pharmaceutical medications that can be used for PCOS symptoms, some patients’ symptoms might not be fully managed, or they might prefer to focus on non-pharmaceutical options for their symptoms instead. Therefore, it is important for clinicians to be familiar with alternatives to the mainstay of pharmaceutical treatment.

Cme:Non-Pharmacologic Management Of Chronic Lower Back Pain (Clbp), Angela Pham

Capstone Showcase

At some time in their life, 84% of adults worldwide will experience lower back pain.¹ Within 4 to 6 weeks, 90% of patients will see resolution or improvement of pain.² However, for patients who are affected by chronic or severe pain, there may be negative outcomes on many other aspects of their lives. Chronic lower back pain (CLBP) is a symptom that may greatly affect day-to-day functioning, sleep, work productivity, and mood. Poorer quality of life, depression, and drug dependency are all associated with CLBP. A comprehensive review from 2018 found strong evidence that patients with chronic pain …

Inpatient Management Of An Intravenous Drug User With Tetanus, Nina Paris

Capstone Showcase

Tetanus is rare in the United States now due to the tetanus vaccine but there is still the potential too see patients with tetanus. IV drug users, neonates, and geriatric populations are at an increased risk of developing tetanus. Tetanus is caused by Clostridium tetani, a spore forming and exotoxin releasing anaerobic bacteria. The symptoms of tetanus are caused by the exotoxin tetanospasmin which inhibits the release of inhibitory neurotransmitters, leading to sustained neuronal stimulation. The classic symptoms of tetanus are lockjaw (trismus), neck stiffness, back arching, and fever. Patients can be febrile, tachycardic, tachypneic, and hypertensive on exam. …