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The Neuroadvocacy Toolkit: A Knowledge Translation Strategy To Strengthen Food Fortification Policies To Prevent Neural Tube Defects In Latin American Countries. A Mixed-Method Study, Kemel A. Ghotme

Doctor of Philosophy in Translational Health Sciences Dissertations

Background. Neural tube defects are one of the leading congenital malformations that affect children in Latin America and worldwide, leading to pregnancy terminations, morbidity, mortality, and long-term disability. The most cost-effective and equitable way to prevent them is by implementing public health policies for food fortification with folic acid. However, a lack of knowledge translation strategies partly accounts for the incomplete enactment, enforcement, and scaling-up of mandatory fortification. There is no evidence in the scientific literature of studies attempting to identify the factors contributing to the development and implementation of knowledge translation strategies aiming to influence policymakers’ decisions regarding mandatory …

Returning Integrated Genomic Risk And Clinical Recommendations: The Emerge Study, Ellen W. Clayton, Jodell E. Linder, Aimee Allworth, Sara T. Bland, 100 Others...

Vanderbilt Law School Faculty Publications

The potential of artificial intelligence (AI) to reduce health care disparities and inequities is recognized, but it can also exacerbate these issues if not implemented in an equitable manner. This perspective identifies potential biases in each stage of the AI life cycle, including data collection, annotation, machine learning model development, evaluation, deployment, operationalization, monitoring, and feedback integration. To mitigate these biases, we suggest involving a diverse group of stakeholders, using human-centered AI principles. Human-centered AI can help ensure that AI systems are designed and used in a way that benefits patients and society, which can reduce health disparities and inequities. …

Full Issue: Summer 2018

DePaul Magazine

The latest issue of DePaul Magazine is now available. In the cover story, see how weathercaster Paul Konrad (THE '87) combines his theatre background and meteorology training as he entertains and informs viewers on WGN-TV Chicago. Get an inside look at his career in "Sunshine State of Mind."

Climate Change, Extreme Events And Mental Health In The Pacific Region, Walter Leal Filho, Murukesan Krishnapillai, Aprajita Minhas, Sannia Ali, Gabriela Nagle Alverio, Medhat Sayed Hendy Ahmed, Roselyn Naidu, Ravinesh R. Prasad, Navjot Bhullar, Ayyoob Sharifi, Gustavo J. Nagy, Marina Kovaleva

Research outputs 2022 to 2026

Purpose: This paper aims to address a gap in investigating specific impacts of climate change on mental health in the Pacific region, a region prone to extreme events. This paper reports on a study on the connections between climate change, public health, extreme weather and climate events (EWEs), livelihoods and mental health, focusing on the Pacific region Islands countries. Design/methodology/approach: This paper deploys two main methods. The first is a bibliometric analysis to understand the state of the literature. For example, the input data for term co-occurrence analysis using VOSviewer is bibliometric data of publications downloaded from Scopus. The second …

Excretory/Secretory Proteome Of Females And Males Of The Hookworm Ancylostoma Ceylanicum, Samuel C Uzoechi, Bruce A Rosa, Kumar Sachin Singh, Young-Jun Choi, Bethany K Bracken, Paul J Brindley, R Reid Townsend, Robert Sprung, Bin Zhan, Maria-Elena Bottazzi, John M Hawdon, Yide Wong, Alex Loukas, Sergej Djuranovic, Makedonka Mitreva

2020-Current year OA Pubs

The dynamic host-parasite mechanisms underlying hookworm infection establishment and maintenance in mammalian hosts remain poorly understood but are primarily mediated by hookworm's excretory/secretory products (ESPs), which have a wide spectrum of biological functions. We used ultra-high performance mass spectrometry to comprehensively profile and compare female and male ESPs from the zoonotic human hookworm

Excretory/Secretory Proteome Of Females And Males Of The Hookworm Ancylostoma Ceylanicum, Samuel C Uzoechi, Bruce A Rosa, Kumar Sachin Singh, Young-Jun Choi, Bethany K Bracken, Paul J Brindley, R Reid Townsend, Robert Sprung, Bin Zhan, Maria-Elena Bottazzi, John M Hawdon, Yide Wong, Alex Loukas, Sergej Djuranovic, Makedonka Mitreva

Faculty, Staff and Students Publications

The dynamic host-parasite mechanisms underlying hookworm infection establishment and maintenance in mammalian hosts remain poorly understood but are primarily mediated by hookworm’s excretory/secretory products (ESPs), which have a wide spectrum of biological functions. We used ultra-high performance mass spectrometry to comprehensively profile and compare female and male ESPs from the zoonotic human hookworm Ancylostoma ceylanicum, which is a natural parasite of dogs, cats, and humans. We improved the genome annotation, decreasing the number of protein-coding genes by 49% while improving completeness from 92 to 96%. Compared to the previous genome annotation, we detected 11% and 10% more spectra in …

Family Income And Cardiovascular Disease Risk In American Adults, Abdul Mannan Khan Minhas, Vardhmaan Jain, Monica Li, Robert W Ariss, Marat Fudim, Erin D Michos, Salim S Virani, Laurence Sperling, Anurag Mehta

Faculty, Staff and Students Publications

Socioeconomic status is an overlooked risk factor for cardiovascular disease (CVD). Low family income is a measure of socioeconomic status and may portend greater CVD risk. Therefore, we assessed the association of family income with cardiovascular risk factor and disease burden in American adults. This retrospective analysis included data from participants aged ≥ 20 years from the National Health and Nutrition Examination Survey (NHANES) cycles between 2005 and 2018. Family income to poverty ratio (PIR) was calculated by dividing family (or individual) income by poverty guidelines specific to the survey year and used as a measure of socioeconomic status. The …

Metabolomics Of A Neonatal Cohort From The Alliance For Maternal And Newborn Health Improvement Biorepository: Effect Of Preanalytical Variables On Reference Intervals, Lena Jafri, Aysha Habib Khan, Muhammad Ilyas, Muhammad Imran Nisar, Javairia Khalid, Hafsa Majid, Aneeta Hotwani, Fyezah Jehan

Department of Pathology and Laboratory Medicine

Background: The study was conducted to determine reference interval (RI) and evaluate the effect of preanalytical variables on Dried blood spot (DBS)-amino acids, acylcarnitines and succinylacetone of neonates.
Methodology: DBS samples were collected within 48-72 hours of life. Samples were analyzed for biochemical markers on tandem mass spectrometer at the University of Iowa. Comparison of RI across various categorical variables were performed.
Results: A total of 610 reference samples were selected based on exclusion criteria; 53.2% being females. Mean gestational age (GA) of mothers at the time of delivery was 38.7±1.6 weeks; 24.5% neonates were of low birth weight and …

Qualitative Study Of Pathways To Care Among Adults With Diabetes In Rural Guatemala, Anita Nandkumar Chary, Meghna Nandi, David Flood, Scott Tschida, Katharine Wilcox, Sophie Kurschner, Pablo Garcia, Peter Rohloff

Faculty, Staff and Students Publications

OBJECTIVE: The burden of diabetes mellitus is increasing in low-income and middle-income countries (LMICs). Few studies have explored pathways to care among individuals with diabetes in LMICs. This study evaluates care trajectories among adults with diabetes in rural Guatemala.

DESIGN: A qualitative investigation was conducted as part of a population-based study assessing incidence and risk factors for chronic kidney disease in two rural sites in Guatemala. A random sample of 807 individuals had haemoglobin A1c (HbA1c) screening for diabetes in both sites. Based on results from the first 6 months of the population study, semistructured interviews were performed with 29 …

Girls’ Education And Child Marriage In Central Africa | Insights From Qualitative Fieldwork Part Ii: The Republic Of Congo, Jean-Christophe Boungou Bazika, Wolf Ulrich Mféré Akiana, Quentin Wodon

Journal of Global Catholicism

Child marriage is defined as a formal or informal union before the age of 18. As in much of sub-Saharan Africa, the prevalence of child marriage remains high in the Republic of Congo (RoC), in part because educational attainment for girls is low. Based on qualitative fieldwork, this article looks at communities’ perceptions of child marriage and girls’ education and their suggestions for programs and policies that could improve outcomes for girls. The article also discusses potential implications for Catholic and other faith-based schools, as well as faith leaders.

Girls’ Education And Child Marriage In Central Africa | Insights From Qualitative Fieldwork Part I: The Democratic Republic Of Congo, Geneviève Bagamboula Mayamona, Jean-Christophe Boungou Bazika, Quentin Wodon

Journal of Global Catholicism

Child marriage is defined as a formal or informal union before the age of 18. As in much of Sub-Saharan Africa, the prevalence of child marriage remains high in the Democratic Republic of Congo (DRC) in part because educational attainment for girls is too low. Based on qualitative fieldwork, this article looks at communities’ perceptions of child marriage and girls’ education and their suggestions for programs and policies that could improve outcomes for girls. The article also discusses potential implications for Catholic and other faith-based schools, as well as faith leaders.

A Two-Day Virtual Workshop On The Micronutrient-Directed Nutrition-Focused Physical Exam For Ghanaian Nutrition Professionals: Examining Perceived Self-Efficacy And Innovation, Leah Anne Qubty, Freda Intiful, Andrea Arikawa, Leslie Van Horn, Lauri Wright

Journal of Dietetic Education

Micronutrients are key components of various physiological processes. In Ghana, micronutrient deficiencies are common and medical resources are limited. Biochemical markers of nutrition status are costly and require specialized medical equipment. In the absence of available biochemical markers of nutrition status, the micronutrient-directed nutrition-focused physical exam is a viable tool. This mixed-methods research aimed to determine whether a two-day virtual workshop for Ghanaian nutrition professionals (N=131) would improve perceptions regarding the usefulness and self-efficacy of the micronutrient-directed nutrition-focused physical exam. Quantitative data were collected via a virtual pretest (immediately prior to the workshop) and a virtual posttest (immediately following the …

Salary Negotiation Among Dietetics Professionals: Lived Experiences And A Three-Pronged Approach To Advancing Negotiation Skills And Confidence, Leila M. Shinn, Suzi Hinck, Lisa Jones, Katie Goldberg, Adrien B. Paczosa, Erin M. Mckinley

Journal of Dietetic Education

There is a lack of tools and training to assist in salary and benefit (S&B) negotiations within the nutrition profession. This study is the first to analyze thoughts, feelings, and experiences with S&B negotiations among nutrition and dietetics professionals. The 32-item, web-based, cross-sectional survey study was completed by English-speaking individuals of any gender who identified as a “nutrition and dietetics professional,” were 18 years of age or older in the United States or US Territory. Participant demographics, experience, confidence, and success with negotiation of S&B, value of negotiation, and interest in learning more were the primary outcome measures determined before …

Integration Of Disability Studies And Culinary Instruction Into Nutrition Curriculum Development, Joanne Sullivan, Regina Subach, Janice Goldschmidt

Journal of Dietetic Education

The Academy of Nutrition and Dietetics is currently promoting the advancement of cultural humility as a means for nutritional professionals to better appreciate the lived experience and identities of others as well as the power dynamics that create health inequalities. At the same time, the Academy has struggled to advance services to underserved populations such as those with Intellectual and Developmental Disabilities (IDD) and autism spectrum disorder. Here the authors argue that both goals can be achieved by involving nutrition students in the teaching of food preparation skills to individuals with IDD. Dietetic students emerge with an enhanced understanding of …

Incorporating Intuitive Eating Education: Dietetics Students’ Perceptions Of Their Eating Behaviors, Body Esteem, And Self-Efficacy To Provide Effective Nutrition Counseling, Alessandra Sarcona, Dara Dirhan

Journal of Dietetic Education

Intuitive eating (IE), an evidence-based, weight-inclusive, hunger-based, and mind-body health approach, is critical for dietitians to know and practice when working with clients to manage their health. Yet, many dietitians are not familiar with the practice of IE, stemming from a lack of training in their dietetics curriculum. The purpose of this mixed-methods study was to investigate the outcomes of creating pedagogical activities incorporating IE education into a senior-level Professional Skills in Dietetics course (Intervention Group [IG]) on students’ eating behaviors, body esteem, and self-efficacy to provide effective nutrition counseling and compare it to junior-level dietetics students in a course …

Navigating The Adoption Of Interprofessional Education As A Performance Standard In Dietetics Education, Paige Whitney, Mary Ann Kluge

Journal of Dietetic Education

Abstract: The purpose of this collective case study was to explore the diffusion of interprofessional education (IPE) in response to specific Future Education Model (FEM) Graduate Program accreditation standards and performance indicators. Data were collected via semi-structured interviews with a purposive sample of 12 FEM program directors from geographically diverse US states. Website and document review were triangulated with the interview data, and Roger’s Diffusion of Innovation (DOI) was used as a theoretical framework to add dimension to the study. Three themes emerged from analysis: 1) Accreditation standards are not the driving force of IPE; 2) Program Directors can serve …

Exploring Dietary Patterns With The Rapid Eating And Activity Assessment For Patients (Reap) Tool In A Dental School Clinic, Katherine Wiley, Rena Zelig, Hamed Samavat, Diane Rigassio Radler

Journal of Dietetic Education

Background: Dietary pattern assessment by healthcare providers leads to a better understanding of usual intake and evaluation of nutritional status, systemic health, and disease. Interprofessional team members can use such information to provide interventions leading to improved health outcomes. Objective: The aim was to explore the dietary patterns of adults seen in a dental clinic using the Rapid Eating and Activity Assessment for Patients (REAP) tool. Methods: This was a cross-sectional study of data from 220 adult patients (aged 18-89 years) who had a diet evaluation completed in a dental school clinic. Demographic information and REAP responses were obtained from …

Table Of Contents, Editors' Message, Editorial Board, Diana Cuy Castellanos, M. Elizabeth (Beth) Miller

Journal of Dietetic Education

No abstract provided.

Full Issue: Summer 2022

DePaul Magazine

In the latest issue of DePaul Magazine, we look at how Eugene P. Jarvis, a trailblazer in the video game industry, and his wife, DePaul Trustee Sasha L. Gerritson (MUS '99), are taking DePaul's College of Computing and Digital Media to the next level with a landmark gift to spur innovation. Also: Robert L. Manuel becomes DePaul's 13th president, DePaul alumnus Jon Irabagon (MUS '00) charts his own course in the jazz world as a performer, composer and producer, initiatives across campus amplify DePaul's commitment to diversity, equity and inclusion (DEI), and DePaul Originals Game Studio Creative Director Allen Turner …

Insulin-Like Growth Factor 1 Reduces Coronary Atherosclerosis In Pigs With Familial Hypercholesterolemia, Sergiy Sukhanov, Yusuke Higashi, Tadashi Yoshida, Svitlana Danchuk, Mitzi Alfortish, Traci Goodchild, Amy Scarborough, Thomas Sharp, James S. Jenkins, Daniel Garcia, Jan Ivey, Darla L. Tharp, Jeffrey Schumacher, Zach Rozenbaum, Jay K. Kolls, Douglas Bowles, David Lefer, Patrice Delafontaine

School of Medicine Faculty Publications

Although murine models of coronary atherosclerotic disease have been used extensively to determine mechanisms, limited new therapeutic options have emerged. Pigs with familial hypercholesterolemia (FH pigs) develop complex coronary atheromas that are almost identical to human lesions. We reported previously that insulin-like growth factor 1 (IGF-1) reduced aortic atherosclerosis and promoted features of stable plaque in a murine model. We administered human recombinant IGF-1 or saline (control) in atherosclerotic FH pigs for 6 months. IGF-1 decreased relative coronary atheroma in vivo (intravascular ultrasound) and reduced lesion cross-sectional area (postmortem histology). IGF-1 increased plaque’s fibrous cap thickness, and reduced necrotic core, …

Cellular Zinc Deficiency Impairs Heme Biosynthesis In Developing Erythroid Progenitors, Juyoung Kim, Jaekwon Lee, Moon-Suhn Ryu

Department of Biochemistry: Faculty Publications

Anemia is the most prevalent nutrition-related disorder worldwide. Zinc is an essential trace element for various biological processes in the body, and zinc deficiency has been associated with anemia in humans. However, the molecular mechanisms by which zinc availability alters red blood cell development remain uncertain. The present study identifies the essentiality of zinc during erythroid development, particularly for normal heme biosynthesis. G1E-ER4 mouse cells were used as an in vitro model of terminal erythroid differentiation, which featured elevated cellular zinc content by development. Restriction of zinc import compromised the rate of heme and -globin production and, thus, the hemoglobinization …

Scavenger Receptor B1 Facilitates The Endocytosis Of Escherichia Coli Via Tlr4 Signaling In Mammary Gland Infection, Qamar Taban, Syed Mudasir Ahmad, Peerzada Tajamul Mumtaz, Basharat Bhat, Ehtishamul Haq, Suhail Magray, Sahar Saleem, Nadeem Shabir, Amatul Muhee, Zahid Amin Kashoo, Mahrukh Hameed Zargar6, Abrar A. Malik, Nazir A. Ganai, Riaz A. Shah

Department of Nutrition and Health Sciences: Faculty Publications

SCARB1 belongs to class B of Scavenger receptors (SRs) that are known to be involved in binding and endocytosis of various pathogens. SRs have emerging role in regulating innate immunity and host–pathogen interactions by acting in co-ordination with Toll-like receptors.Query Little is known about the function of SCARB1 in milk-derived mammary epithelial cells (MECs). This study reports the role of SCARB1 in infection and its potential association in TLR4 signaling on bacterial challenge in Goat mammary epithelial cells (GMECs). The novelty in the establishment of MEC culture lies in the method that aims to enhance the viability of the cells …

Experience, Training Preferences, And Fighting Style Are Differentially Related To Measures Of Body Composition, Strength, And Power In Male Brazilian Jiu Jitsu Athletes - A Pilot Study, Christian G. Almeda, Gerald T. Mangine, Zackary H. Green, Yuri Feito, Duncan N. French

Research outputs 2022 to 2026

To examine relationships between Brazilian Jiu Jitsu (BJJ) descriptors (belt rank, experience, gi preference, and fighting style), resistance training (RT) experience, and measures of body composition, strength (maximal handgrip, 3-5-repetition maximum [RM] in barbell glute bridge [GB], prone bench row [PBR], and bench press [BP]), and velocity (GB, PBR, and BP at 7 kg and 30 – 60 % 1-RM), 13 experienced (4.3 ± 3.4 years) BJJ athletes were recruited for this cross-sectional, pilot study. Significant (p < 0.05) Kendall’s tau and Bayesian relationships were seen between belt rank and body fat percentage (τ = − 0.53, BF₁₀ = 6.5), BJJ experience and body fat percentage (τ = − 0.44 to − 0.66, BF₁₀ = 2.6 – 30.8) and …

Establishing An In Vitro Model To Study Avian Carotenoid Ketolation, Chidimma Okegbe

Electronic Theses and Dissertations Archive

Carotenoid coloration is among the most widely recognized condition-dependent signal of quality in animals. This project first explored the possibility of establishing an in-vitro model to study carotenoid ketolation in two avian species, where both species use red keto-carotenoids for plumage pigmentation. Secondly, this project tested whether the carotenoid ketolation pathway would be affected by antioxidant and mitochondrial uncoupler treatments. We observed that most carotenoid ketolation could happen in in-vitro settings using primary hepatocytes for both House Finch and Domestic Canary. However, interestingly, the in-vitro system using House Finch hepatocytes failed to convert β-cryptoxanthin to 3-HE. Then, we tested the …

Home Visitation To Prevent And Reduce Postpartum Depression, Anna Bauer, Madison Polley, Laura Boesken Dnp, Msn, Rn

Posters-at-the-Capitol

Postpartum depression (PPD) occurs in 13-19% of women worldwide, and is a stigmatized medical condition affecting maternal and infantile long term outcomes. The purpose of this evidence-based practice project was to determine if women at high risk for PPD are affected by home visitation programs from discharge up to three years postpartum. CINHAL Ultimate, Google Scholar, and Medline databases were used. Current evidence supports the use of home-visitation programs for postpartum women to decrease the prevalence and the symptoms of PPD by allowing nurses access into homes to provide early intervention for PPD. In addition to providing care for prevention …

Innovate Ag Tech, Not Ag Tort: Why Legislative And Judicial Policies Favoring Tech Innovation And Big Ag's Ip Rights In Gmos Will Benefit Agricultural Production And Food Security, Gage Patton

Journal of Intellectual Property Law

Genetically modified organisms ("GMOs") play a critical role in technological advances in agriculture. GMOs contribute to generating higher crop yields, reduce the need for pesticide application, and even reduce food waste. Virtually all GMO technologies are developed by a small number of very large agricultural corporations. These corporations are responsible for the vast majority of research and development efforts for agricultural technologies. Agricultural research and development yields technological innovation, which produces better methods of food production. Therefore, the research and development efforts that big ag corporations engage in benefit everyone by providing better methods of food production. However, some critics …

Development Of A Micro-Credential Curriculum: The Interprofessional Dementia Caregiving Telehealth Community Practicum Badge, Susan L. Wenker, Chinh Kieu, Tracy Schroepfer, Kristen Felten, Kathleen Smith, Hossein Khalili

Internet Journal of Allied Health Sciences and Practice

Purpose: Informal dementia caregiving by family caregivers is a crucial component of the care provided to people living with dementia (PLwD). The numbers of these family caregivers are rapidly increasing at a time, when in the U.S., the availability of formal caregivers is decreasing. Currently, health professional training focuses on providing care to PLwD and not necessarily addressing the caregiver’s needs, and this training takes place within professional silos and not interprofessionally. This study sought to address this issue by: 1) examining the current state of interprofessional dementia caregiving trainings in the US; and 2) developing a micro-credential curriculum called …

Burnout And Adverse Outcomes In Athletic Training Students: Why All Healthcare Educators Should Be Concerned, Ashlyne P. Elliott, Andrew Gallucci, Leslie Oglesby, Leslee Funderburk, Beth A. Lanning, Sara Tomek

Internet Journal of Allied Health Sciences and Practice

Background: Burnout is linked to various adverse outcomes (i.e., thoughts of dropout, depression, unprofessional behaviors) in healthcare students (i.e., nursing students, medical students). However, potential adverse outcomes associated with burnout in athletic training students, a subset of healthcare students, have yet to be identified. Objective: To adapt a previously tested theoretical model to explore relationships between student workload, burnout, and potential adverse outcomes in a sample of graduate athletic training students. Methods: An online survey assessing the variables of interest and study information was sent to program directors of graduate-level athletic training programs at their publicly accessible email addresses with …

Preparing For The Next Disaster: Lessons Learned From The Early Experiences Of Autistic Adults During The Covid-19 Pandemic, Amber Pomponio Davidson, Cecilia Feeley, Beth Pfeiffer, Mark Salzer

Internet Journal of Allied Health Sciences and Practice

Purpose: Disasters, such as the worldwide COVID-19 pandemic, create significant disruptions for individuals and their communities. Understanding these disruptions is a first step towards planning for future events and disaster recovery. This research aims to explore how the initial COVID-19 restrictions, including lockdowns, impacted adults with Autism (ASD). Method: Using semi-structured interviews to understand how individuals with ASD experienced the early months of the COVID-19 pandemic, twelve participants were interviewed: six individuals with ASD (ages 20-38), three parents of individuals with ASD, and three support staff for individuals with ASD. Analysis: Grounded theory methods were used to analyze the impacts …

Mealtime Experiences Of Children With Autism Spectrum Disorder From The Perspectives Of Filipino Occupational Therapists In Cebu: Implications For Practice, Blaise Audre V. Barrientos, Alyanna Freyse T. Badajos, Erika Faye M. Bucog, Rosse Velle C. Mauro, Paolo Miguel P. Bulan

Internet Journal of Allied Health Sciences and Practice

Purpose: Occupational therapists (OTs) handle children diagnosed with autism spectrum disorder (ASD), and a common concern is how their sensory processing issues affect their feeding habits. There is limited information regarding interventions about this issue both locally and internationally. This study aims to know the experiences of OTs providing feeding interventions associated with sensory issues for children with ASD. It will also describe what approaches they used for these interventions. Method: Qualitative phenomenology using in-depth interviews with nine OTs in Cebu, Philippines was conducted, and data underwent thematic analysis. Results: Five themes emerged: 1) a family that feeds together, stays …