Digital Commons Network^™

Circadian Rhythms As Modulators Of Brain Health During Development And Throughout Aging, Rachel Van Drunen, Kristin Eckel-Mahan

Faculty, Staff and Student Publications

The circadian clock plays a prominent role in neurons during development and throughout aging. This review covers topics pertinent to the role of 24-h rhythms in neuronal development and function, and their tendency to decline with aging. Pharmacological or behavioral modification that augment the function of our internal clock may be central to decline of cognitive disease and to future chronotherapy for aging-related diseases of the central nervous system.

A Comprehensive Assessment Of Cell Type-Specific Differential Expression Methods In Bulk Data, Guanqun Meng, Wen Tang, Emina Huang, Ziyi Li, Hao Feng

Faculty, Staff and Student Publications

Accounting for cell type compositions has been very successful at analyzing high-throughput data from heterogeneous tissues. Differential gene expression analysis at cell type level is becoming increasingly popular, yielding biomarker discovery in a finer granularity within a particular cell type. Although several computational methods have been developed to identify cell type-specific differentially expressed genes (csDEG) from RNA-seq data, a systematic evaluation is yet to be performed. Here, we thoroughly benchmark six recently published methods: CellDMC, CARseq, TOAST, LRCDE, CeDAR and TCA, together with two classical methods, csSAM and DESeq2, for a comprehensive comparison. We aim to systematically evaluate the performance …

Ultrasound Assessment Of Spastic Muscles In Ambulatory Chronic Stroke Survivors Reveals Function-Dependent Changes, Javier González-Buonomo, Alexander H Pham, Jaskiran Ghuman, Aila Malik, Nuray Yozbatiran, Gerard E Francisco, Walter R Frontera, Sheng Li

Faculty, Staff and Student Publications

OBJECTIVE: To correlate ultrasound characteristics of spastic muscles with clinical and functional measurements in chronic stroke survivors.

METHODS: Ultrasound assessment and clinical and functional assessments were performed in 28 ambulatory stroke survivors (12 females, mean age 57.8 ± 11.8 years, 76 ± 45 months after stroke).

RESULTS: Muscle thickness in the affected side was decreased compared with the contralateral side (p < 0.001). The decrease was more evident in the upper limb muscles. On the affected side, the modified Heckmatt scale score was lowest (closer to normal) in the rectus femoris (RF) muscle compared with other muscles (biceps brachii (BB), flexor carpi ulnaris (FCU) and medial gastrocnemius (MG)). Muscle thickness and echogenicity of spastic muscles did not correlate with spasticity, as measured with the modified Ashworth scale (MAS), Fugl-Meyer motor assessment scores, age, or time since stroke. There was a significant negative correlation between grip strength and percentage decrease in muscle thickness for the spastic FCU muscle (r = -0.49, p = 0.008). RF muscle thickness correlated with ambulatory function (Timed Up and Go test (r = 0.44, p = 0.021) and 6-metre walk test (r = 0.41, p = 0.032)). There was no significant correlation between echogenicity and functional assessments Conclusion: Ambulatory chronic stroke survivors had function-dependent changes in muscle thickness on the affected side. Muscle thickness and echogenicity of spastic muscles did not correlate with spasticity, Fugl-Meyer motor assessment scores, age, or time since stroke.

The Effect Of Led Light Spectra On The Growth, Yield And Nutritional Value Of Red And Green Lettuce (Lactuca Sativa), Abdullah A. Alrajhi, Abdulaziz S. Alsahli, Ibrahim M. Alhelal, Hail Z. Rihan, Michael P. Fuller, Abdullah A. Alsadon, Abdullah A. Ibrahim

School of Biological and Marine Sciences

Controlled Environment Agriculture (CEA) is a method of increasing crop productivity per unit area of cultivated land by extending crop production into the vertical dimension and enabling year-round production. Light emitting diodes (LED) are frequently used as the source of light energy in CEA systems and light is commonly the limiting factor for production under CEA conditions. In the current study, the impact of different spectra was compared with the use of white LED light. The various spectra were white; white supplemented with ultraviolet b for a week before harvest; three combinations of red/blue lights (red 660 nm with blue …

The Student Movement Volume 107 Issue 12: Revisiting "The Dream": Students Celebrate Mlk Day, Grace No, Nora Martin, Gloria Oh, Ysabelle Fernando, Solana Campbell, Amelia Stefanescu, Brendan Oh, Julia Randall, Gabriela Francisco, Peter Lyons, Anthony Bosman, Martin Hanna, Ryan T. Hayes, Karin Thompson, Melissa Moore, Wambui Karanja, Desmond H. Murray, Scott Moncrieff

The Student Movement v. 107 (2022-2023)

HUMANS

Andrews Gaming Club, Interviewed by: Grace No

Meet Gio Lee, Interviewed by: Nora Martin

New Year, Happier Me, Gloria Oh

ARTS & ENTERTAINMENT

Art @ AU: Harrigan's Gallery, Ysabelle Fernando

Currently: The Way of Water, Solana Campbell

Ode to 2022, Amelia Stefanescu

Where Do I Find God - Part I, Anonymous

NEWS

Honoring Martin Luther King Jr.'s Legacy, Brendan Oh

Is America Safe?: First Grader Shoots Teacher, Julia Randall

A House Divided: Current Issues Within the School of Architecture and Interior Design, Student Movement Editorial Staff

IDEAS

Harry & Meghan: Unpacking Royal Pains, Gabriela Francisco

A New Space for …

Exploring The Link Between Food Insecurity And Eating Disorders, Ayden Hayes

Electronic Theses and Dissertations Archive

In the last five years, research regarding the link between food insecurity and eating disorders has been on the rise. This review was conducted to explore this link and identify potential gaps and limitations that exist among the current research and how future research can address these. Evidence gathered throughout this review supports a need for changes to screening tools for eating disorders as well as food assistance programs, which indicates some ways that this research can direct future practice for nutrition professionals. The Academy of Nutrition and Dietetics defines disordered eating as irregular eating patterns that are not indicative …

Socio-Demographic Determinants Of Non-Utilisation Of Antenatal Care Services By Women In The Northern Region Of Nigeria, Abubakar Yakubu Abbani, Yothin Sawangdee, Olusola Akintoye Omisakin, Maretalinia Maretalinia

Journal of Health Research

Background: A large proportion of women in the northern region of Nigeria do not utilise antenatal care (ANC) services. As a result, the region has the worst maternal and child health indicators. This study aims to identify the socio-demographic determinants of the non-utilisation of ANC services by pregnant women to provide evidence for policymakers to base decisions towards addressing the problem.

Methods: Data from the 2018 Nigeria Demographic and Health Survey was used with a sample of 14,421 women with a pregnancy history. Descriptive, bivariate, and hierarchical regression analyses were applied to the data using STATA software version 15.

Results: …

Health Problems, Healthcare Service Utilisation And Its Associated Factors Among The Homeless In Malaysia: A Systematic Review, Fadly Syah Arsad, Rozita Hod, Mohd Rizal Abdul Manaf

Journal of Health Research

Background: Homelessness is a growing concern since it affects many individuals worldwide. Homeless people are vulnerable to health problems but tend to underutilise health services. Despite being a worldwide concern, there is little research on health issues and healthcare utilisation among homeless people in Malaysia.

Method: Three databases were used to search for relevant articles: Scopus, Web of Science, and PubMed. Studies published between 2011 and 2021 that examined the health problems and health service utilisation among homeless adults in Malaysia were considered. Manual searches in reference lists and grey literature were also performed to add reports. Data were extracted …

Effect Of The Culturally Tailored Diabetes Prevention Program For At-Risk Thai Muslim People In Semi-Urban Areas, Yuparat Odglun, Kitti Sranacharoenpong, Nattvara Nirdnoy

Journal of Health Research

Background: Lifestyle intervention is effective in preventing type 2 diabetes mellitus (T2DM). The efficacy of intervention components across different sociocultural settings is relevant for real world implementation. Thus, this study aimed to evaluate the effectiveness of a culturally tailored diabetes prevention program (CTDPP) for at-risk Muslim people in Thailand.

Method: The CTDPP was developed and culturally adapted based on formative research. Participants at risk for diabetes were recruited and randomly assigned to either the intervention group (n=60) or the control group (n=59). Study group subjects participated in the CTDPP for 3 months. Control group subjects received only routine self-care recommendations …

Patent Forfeiture, Sean B. Seymore

Duke Law Journal

Patent law doesn’t look kindly on patent owners who engage in wrongdoing involving the patent. The U.S. Supreme Court and lower courts have refused to enforce patents tainted with inequitableness, fraud, or bad faith. This issue typically arises in patent litigation when an accused infringer asserts that the patent should be unenforceable if the patentee engaged in one of four proscribed activities: inequitable conduct (deliberate misrepresentations or omissions of material information from the Patent Office); patent misuse (anticompetitive licensing practices); unclean hands (business or litigation misconduct); or waiver/estoppel (a lack of candor before a standard-setting organization). This seems right—a patentee …

To Use Or Not Use: Understanding Chinese Consumers' Intention Toward “Serving Chopsticks”, Qian Chen, Rong Huang, Aiping Zhang, Yingzhi Guo

Plymouth Business School

Serving chopsticks (or “community-use chopsticks”) refers to chopsticks that are used to serve food from a shared dish to an individual's plate, they are used because of concerns about hygiene. This study aims to examine consumers' perceived values toward serving chopsticks and provide an insight into the formation of consumers' intentions to use serving chopsticks. A mixed-method approach was utilized to collect data; interviews were conducted with 62 consumers, followed by a web-based survey with 630 consumers. Qualitative analysis and structural equation modeling analysis were used in the data analysis. Qualitative analysis highlighted four dimensions that contribute to consumers' perceived …

Prescribing Patterns Of Myopia Control Contact Lenses Among Optometrists In Ireland, Michael Moore, Daniel Ian Flitcroft, James Loughman

Articles

Purpose

This retrospective analysis of electronic medical record (EMR) data investigated the prescribing patterns of soft myopia control contact lens (MCCL) treatments since their introduction in Ireland in 2017.

Methods

Anonymised EMR data were sourced from 33 optometry practices in Ireland from 2017 to 2021 to determine the number of practices prescribing MCCLs to myopic children 5–18 years old. In MCCL-prescribing practices, the proportion of contact lens wearing children fitted with MCCLs and the proportion of progressive (≤−0.25 D/year) myopic children fitted with MCCLs were determined. Logistic regression was used to determine which factors influenced the likelihood of being prescribed …

Experiences Of Food Insecure College Students During The Covid-19 Pandemic, Amy E. Kendrick

Dissertations

The aims of this qualitative descriptive study were to describe the experiences and needs of food insecure college students during the COVID-19 pandemic and to obtain foundational information about food insecurity during a public health crisis to provide guidance for the development of future interventions.

Effect Of Hormone Replacement Therapy On Bone Health And Density In Transgender Individuals, Ashley Marie Krueger

Electronic Theses and Dissertations Archive

Background: This article is an examination of the effects of hormone replacement therapy on bone health and density in transgender individuals. The use of gender affirming hormone therapy and surgery is on the rise nationally. This bears the question: what side effects may result from use? Hormones have previously been studied for their protective effects on bone health, but there is a distinct lack of research into the effects of long-term gender-affirming hormone therapy. Objective: To answer the research question: What effect does gender-affirming hormone therapy have on bone density in adult and adolescent transgender individuals over at least a …

Association Of Omega 3 Polyunsaturated Fatty Acids With Incident Chronic Kidney Disease: Pooled Analysis Of 19 Cohorts, Kwok Leung Ong, Matti Marklund, Liping Huang, Kerry-Anne Rye, Nicholas Hui, Xiong-Fei Pan, Casey M Rebholz, Hyunju Kim, Lyn M Steffen, Anniek C Van Westing, Johanna M Geleijnse, Ellen K Hoogeveen, Yun-Yu Chen, Kuo-Liong Chien, Amanda M Fretts, Rozenn N Lemaitre, Fumiaki Imamura, Nita G Forouhi, Nicholas J Wareham, Anna Birukov, Susanne Jäger, Olga Kuxhaus, Matthias B Schulze, Vanessa Derenji De Mello, Jaakko Tuomilehto, Matti Uusitupa, Jaana Lindström, Nathan Tintle, William S Harris, Keisuke Yamasaki, Yoichiro Hirakawa, Toshiharu Ninomiya, Toshiko Tanaka, Luigi Ferrucci, Stefania Bandinelli, Jyrki K Virtanen, Ari Voutilainen, Tharusha Jayasena, Anbupalam Thalamuthu, Anne Poljak, Sonia Bustamante, Perminder S Sachdev, Mackenzie K Senn, Stephen S Rich, Michael Y Tsai, Alexis C Wood, Markku Laakso, Maria Lankinen, Xiaowei Yang, Liang Sun, Huaixing Li, Xu Lin, Christoph Nowak, Johan Ärnlöv, Ulf Risérus, Lars Lind, Mélanie Le Goff, Cécilia Samieri, Catherine Helmer, Frank Qian, Renata Micha, Adrienne Tin, Anna Köttgen, Ian H De Boer, David S Siscovick, Dariush Mozaffarian, Jason Hy Wu

Faculty, Staff and Students Publications

OBJECTIVE: To assess the prospective associations of circulating levels of omega 3 polyunsaturated fatty acid (n-3 PUFA) biomarkers (including plant derived α linolenic acid and seafood derived eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid) with incident chronic kidney disease (CKD).

DESIGN: Pooled analysis.

DATA SOURCES: A consortium of 19 studies from 12 countries identified up to May 2020.

STUDY SELECTION: Prospective studies with measured n-3 PUFA biomarker data and incident CKD based on estimated glomerular filtration rate.

DATA EXTRACTION AND SYNTHESIS: Each participating cohort conducted de novo analysis with prespecified and consistent exposures, outcomes, covariates, and models. The results were …

Photography As A Wellness Tool For Counselors-In-Training, Charaya C. Upton, Joel F. Diambra, Pamelia E. Brott, Zach Budesa

Journal of Educational Research and Practice

The academic journey to become a professional counselor can be challenging for counselors-in-training (CIT), adversely affecting their physical health, mental health, and wellness. Counselor educators (CE) have recognized a need for wellness training and interventions to assist CIT during graduate school and to prepare them for their careers. Photography is considered a tool in art therapy within the realm of expressive therapies that can be used for wellness purposes. We review wellness, CIT struggles with wellness, expressive therapies, and photography techniques to promote CIT professional development and wellness practices. We identify the history of photography tools, describe each tool more …

Social Justice In India: A Comparative Study Of Rawls And Ambedkar, Abinash Darnal

Comparative Philosophy

Justice has always been central to political philosophy over a period of time. No doubt, throughout the ages, countless philosophers have understood justice in different ways. Nevertheless, they have consented that a good society is a just society. Moreover, justice is a distributive concept and is concerned with the distribution of wealth, leisure, liberty, friendship, love, etc. Twentieth century justice came to be discussed usually in relation to social life in general, and the distribution of material rewards in particular and usually came to be known as ‘Social Justice’. Social justice as such came to be accepted as the fair …

The Impact Of Theoretical Knowledge Acquisition On Practical Clinical Skills: Multi-Disciplinary Retrospective Study, Ramy Ameen Fodah, Abdulaziz Ibrahim Al Hassan, Ahmad A. Alanazi, Mohammed Khalaf Al Mutairi, Syed Alamdar Shah

Health Professions Education

Purpose. Assessment drives learning, and one assessment tool cannot measure all students learning competencies. Thus, multiple methods of assessment were developed to address this matter. This study aimed to measure whether in-classroom theoretical knowledge impacts students’ mastery of practical clinical skills and whether a strong association between the two parameters exists.

Methods. A retrospective, correlational study design was conducted to examine the correlation between the theoretical knowledge (assessed by final written MCQs examination) and students’ practical clinical skills (assessed by OSCE and/or OSPE). Two batches of male and female students (a total of 478) were included in the study from …

2023 January 17 - Medical Student Education Committee Retreat Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Uab Study Says 75 Percent Of Young Adults In The U.S. Do Not Have Ideal Cardiovascular Health, Anna Jones

Browse All News

No abstract provided.

Breast Milk Jaundice (Nursing), Stephanie Bratton, Rebecca M. Cantu, Mitchell Stern, Wanda Dooley

Nursing and Health Sciences

No abstract provided.

Identification Of Cancer Related Risk And Protective Factors For American Indian Youth: A Mixed Studies Review, Melanie Nadeau, Kathryn Wise, Vianca Farfan Cuela, Devon Olson, Karan Saravana

Indigenous Health Faculty Publications

Introduction: Many causes of cancer related morbidity and mortality can be traced back to childhood behaviors. The culmination of cancer related risk and protective factors impacting the health and wellbeing of American Indian youth is unknown. The aim of this Mixed Studies Review was to identify cancer related risk and protective factors among American Indian youth. Results will be shared with Tribal communities to inform surveillance efforts.

Methods: A Mixed Studies Review process was deemed most appropriate for the search process and data collection. 7 databases were included in the search along with 3 databases that were hand searched. Google …

Food Insecurity Is A Common Problem For Military Service Members And Their Families, Colleen Heflin, Gabriella Alphonso

Population Health Research Brief Series

Food insecurity has negative effects on military service members and their families, including their work performance, professional success, and health and wellness. A recent memorandum released by the U.S. Office of the Under Secretary of Defense for Personnel and Readiness shows that in 2020, nearly 1 in 4 U.S. active-duty service members experienced food insecurity and that participation in benefits such as the Supplemental Nutritional Assistance Program (SNAP) is low. This brief summarizes the key findings from the memorandum and discusses what can be done to improve food security among active-duty military members and their families.

Impact Of A Dietitian In General Practice: Paediatric Food Allergy: Paediatric Food Allergy, Avril Collinson, Lisa Waddell, Amy Freeman-Hughes, Mary Hickson

School of Health Professions

BACKGROUND: Food allergy in infants and young children places a significant burden on primary care. This study evaluated a dietetic-led paediatric food allergy service, which attempts to provide more rapid access to the dietitian and reduce the need for general practitioner (GP) and secondary care appointments.

METHODS: Two community dietetic services for children referred with food allergy were compared. The first was dietetic-led care where dietitians train community children's nurses to recognise potential cases of food allergy, undertake basic diagnostic assessment and subsequently refer to the dietitian. The other was a more traditional dietetic community service where patients were referred …

Climate Change, Human Health, And Resilience In The Holocene, Gwen Robbins Schug, Jane E. Buikstra, Sharon N. Dewitte, Brenda J. Baker, Elizabeth Berger, Michele R. Buzon, Anna M. Davies-Barrett, Lynne Goldstein, Anne L. Grauer, Lesley A. Gregoricka, Siân E. Halcrow, Kelly J. Knudson, Clark Spencer Larsen, Debra L. Martin, Kenneth C. Nystrom, Megan A. Perry, Charlotte A. Roberts, Ana Luisa Santos, Christopher M. Stojanowski, Jorge A. Suby, Daniel H. Temple, Tiffany A. Tung, Melandri Vlok, Tatyana Watson-Glen, Sonia R. Zakrzewski

Anthropology: Faculty Publications and Other Works

Climate change is an indisputable threat to human health, especially for societies already confronted with rising social inequality, political and economic uncertainty, and a cascade of concurrent environmental challenges. Archaeological data about past climate and environment provide an important source of evidence about the potential challenges humans face and the long-term outcomes of alternative short-term adaptive strategies. Evidence from well-dated archaeological human skeletons and mummified remains speaks directly to patterns of human health over time through changing circumstances. Here, we describe variation in human epidemiological patterns in the context of past rapid climate change (RCC) events and other periods of …

Examining Stripes On A Herd Of Zebras: Impact Of Genomic Matching For Ultrarare Sarcomas In Phase 1 Clinical Trials (Samba 102), Justin T Moyers, Roberto Carmagnani Pestana, Jason Roszik, David S Hong, Aung Naing, Siqing Fu, Sarina Piha-Paul, Timothy A Yap, Daniel Karp, Jordi Rodon, Andy Livingston, Maria Alejandra Zarzour, Vinod Ravi, Shreyaskumar Patel, Robert S Benjamin, Joseph Ludwig, Cynthia Herzog, Ravin Ratan, Neeta Somaiah, Anthony Conley, Richard Gorlick, Funda Meric-Bernstam, Vivek Subbiah

Faculty, Staff and Student Publications

Purpose: Recently, the Connective Tissue Oncology Society published consensus guidelines for recognizing ultrarare sarcomas (URS), defined as sarcomas with an incidence ≤1 per 1,000,000. We assessed the outcomes of 56 patients with soft tissue, and 21 with bone sarcomas, enrolled in Phase 1 trials.

Experimental design: In this Sarcoma-Matched Biomarker Analysis (SAMBA-102 study), we reviewed records from patients on Phase 1 trials at the University of Texas MD Anderson Cancer Center between January 2013 and June 2021.

Results: Among 587 sarcomas, 106 (18.1%) were classified as URS. Fifty (47%) were male, and the median age was 44.3 years (range, 19-82). …

A Process Evaluation Of Post-Secondary Programs For High Functioning Students On The Autism Spectrum, Richard A. Spirito Jr.

Seton Hall University Dissertations and Theses (ETDs)

ABSTRACT

The purpose of this study was to evaluate how the post-secondary programs in the Mid-Atlantic region of the United States are supporting the needs of students with autism spectrum disorder (ASD) and preparing them for future independence.

According to the CDC (Centers for Disease Control and Prevention), the number of children diagnosed with autism spectrum disorder is on the rise. In 2000, one in 150 children were identified with autism spectrum disorder. That number rose to one in every 44 children in the United States that have been identified with autism spectrum disorder in 2010.

As these students reach …

Killing The Indian To Save The Tribe: The Effect Of Federal Indian Policy On Reservation Economy And The Lives Of Individual Members, Elizabeth Morris, Tania Blackburn

Liberty University Journal of Statesmanship & Public Policy

Federal Indian policy’s infringement on individuality, liberty and property is the reason many Native Americans continue to struggle in poverty. Through a systematic literature review, it is demonstrated that allowing property rights for individual members, and removing the financial incentive for tribal leaders to use tribal members, and especially children as property, would both vastly improve the economy and preserve to people their God-given right to life, faculties, and production. This would be a significant first step to unlocking real self-determination, human potential and ingenuity, as well as correct the long-standing policies that have robbed generations of Indian people of …

The Utah Statesman January 16, 2023, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Retrospective Study Of Healthcare Resources Developed For Patients By Interprofessional Teams, Rebecca White, Ashley Walczybock, Jennifer Mendez, Ashley Reed, Shannon Maloney, Michelle Malik, Christine Kivlen

Internal Medicine Faculty Publications

Wayne State University (WSU) emphasizes the importance of interdisciplinary education by having students participate in an Interprofessional Team Visit (IPTV) program. A 60-minute virtual visit is conducted to assess adults aged over 50 years within the Detroit Metropolitan Area (Metro Detroit) community. This project was designed to prepare healthcare students in evaluating the mental, physical, and social health aspects of assigned patients based on specific disciplinary assessments. Upon completion of assessments, the interdisciplinary team provided the patient with resources based on the team and the patient's agreed-upon area of concern. Twenty-eight IPTV teams, consisting of a medical and occupational therapy …