Digital Commons Network^™

Drought Stress Prediction And Propagation Using Time Series Modeling On Multimodal Plant Image Sequences, Sruti Das Choudhury, Sinjoy Saha, Ashok Samal, Anastasios Mazis, Tala Awada

School of Natural Resources: Faculty Publications

The paper introduces two novel algorithms for predicting and propagating drought stress in plants using image sequences captured by cameras in two modalities, i.e., visible light and hyperspectral. The first algorithm, VisStressPredict, computes a time series of holistic phenotypes, e.g., height, biomass, and size, by analyzing image sequences captured by a visible light camera at discrete time intervals and then adapts dynamic time warping (DTW), a technique for measuring similarity between temporal sequences for dynamic phenotypic analysis, to predict the onset of drought stress. The second algorithm, HyperStressPropagateNet, leverages a deep neural network for temporal stress propagation using hyperspectral imagery. …

Household Food Security In The Mountain West, 2021, Zachary Walusek, Corryn Richardson, Issac Hernandez-Alcaraz, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.

Health

This fact sheet examines data on household food security published by the United States Department of Agriculture. We examine the prevalence of household food insecurity and very low food security in Mountain West states (Arizona, Colorado, Nevada, New Mexico, and Utah) and the United States national average for comparative analysis.

Comfrey In The Garden, Emmalee Rolfe, Dan Drost

All Archived Publications

Comfrey (Symphytum officinale) is a very hardy perennial herb adaptable to most conditions. Comfrey grows best in partial to full sun in moist, fertile soil. Comfrey is propagated by root cuttings or crown divisions. Comfrey can be planted throughout the growing season but establishes best when planted in the spring. Maintain moderate soil moisture, especially when plants are young. Once established, comfrey outcompetes weeds and does not have any reported insect or disease issues in Utah. Some leaves and roots are harvested after the first year of growth. It should be noted that consuming high doses or excessive …

Investigating The Reptilian Innate Immune System: A Review And Examination Of The Relationship Between Immunity, Stress, And Reproduction, Emily Katherine Field

Student Theses and Dissertations

Ecoimmunology examines the relationship between the physiology of an organism, its immune responses, and the external environment. As such, this field is critical to answering important questions in ecology, physiology, and evolution, and it can be vital in making policy and conservation decisions. As the only ectothermic amniotes, class Reptilia represents a group of unique study organisms. However, in comparison to other vertebrate taxa, this group has remained relatively understudied in the field of ecoimmunology. Though reptilian immunology has gained some attention in the last decade, we still lack data assessing immunity across the four orders of class Reptilia. Immune …

Periconceptual Maternal Nutrition Affects Fetal Liver Programming Of Energy- And Lipid-Related Genes, Wellison J. S. Diniz, Alison K. Ward, Kacie L. Mccathy, Cierrah J. Kassetas, Friederike Baumgaertner, Lawrence P. Reynolds, Pawel P. Borowicz, Kevin K. Sedivec, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, J. Chris Forcherio, Ronald Scott, Joel S. Caton, Carl R. Dahlen

Department of Animal Science: Faculty Publications

During pregnancy, the fetus relies on the dam for its nutrient supply. Nutritional stimuli during fetal organ development can program hepatic metabolism and function. Herein, we investigated the role of vitamin and mineral supplementation (VTM or NoVTM—at least 71 days pre-breeding to day 83 of gestation) and rate of weight gain (low (LG) or moderate (MG)—from breeding to day 83) on the fetal liver transcriptome and the underlying biological pathways. Crossbred Angus beef heifers (n = 35) were randomly assigned to one of four treatments in a 2 × 2 factorial design (VTM_LG, VTM_MG, NoVTM_LG, and NoVTM_MG). Gene expression …

Institutional Grantmaking To New Hampshire Nonprofits, Jess Carson, Alison Moore

Carsey Publications

In 2019, the New Hampshire Funders Forum contacted the Carsey School of Public Policy at the University of New Hampshire for support in creating an inaugural report on institutional grantmaking in the state. After initial exploration raised questions about the comprehensiveness of existing data sources, the Funders Forum commissioned Carsey to develop an alternate approach utilizing original tax filings to create the most accurate and comprehensive portrait of institutional grantmaking in the state available. This report represents the culmination of that effort and is intended to provide a baseline description of institutional grantmakers that support New Hampshire nonprofits for members …

February 9, 2023, Caa

Minutes

No abstract provided.

Current And Emerging Therapies For Atherosclerotic Cardiovascular Disease Risk Reduction In Hypertriglyceridemia, Reed Mszar, Sarah Bart, Alexander Sakers, Daniel Soffer, Dean G. Karalis

Division of Cardiology Faculty Papers

Hypertriglyceridemia (HTG) is a prevalent medical condition in patients with cardiometabolic risk factors and is associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD), if left undiagnosed and undertreated. Current guidelines identify HTG as a risk-enhancing factor and, as a result, recommend clinical evaluation and lifestyle-based interventions to address potential secondary causes of elevated triglyceride (TG) levels. For individuals with mild to moderate HTG at risk of ASCVD, statin therapy alone or in combination with other lipid-lowering medications known to decrease ASCVD risk are guideline-endorsed. In addition to lifestyle modifications, patients with severe HTG at risk of acute pancreatitis …

An Analysis Of Social Media Operations In The King Salman Humanitarian Organization Aid And Relief Center, Nasser Abudulrahman Alkhulayfi

Student Theses and Dissertations

Although social media is widely used by non-profit organizations (NPO) to raise funds, little is known about how it is used and how it can be utilized for fundraising. This study provides an analysis of the various aspects of social media and its use for fundraising by focusing on the data of humanitarian aid provisions of King Salman's humanitarian organization in Saudi Arabia. The data collected came from Facebook, Twitter, and Instagram, from October 2019 to May 2022. The study used the search terms: "coronavirus", "quick fix" and "helpful." For data analysis, n-Vivo software was used. The study looks into …

Assessment Of Variable Rate Nitrogen Application On Rice Cultivars Using Remote Sensing, Rush Matthew Evans

Student Theses and Dissertations

Application of the right time and amount of fertilizer N is challenging in rice fertilization because crop N supply is highly variable in the field. Research plots were established at four research plot fields and one commercial field in Arkansas. Independent variables included six nitrogen (N) application rates (0, 67, 101, 134.5, 168, and 202 kg N ha-1), multiple rice cultivars, and five locations. The response variable was 24 vegetative indices values using high spatio-temporal multispectral and thermal imagery obtained from an Unmanned Aerial Vehicle (UAV). The 134 and 168 kg N ha-1 rates were identified as the control group …

Evaluation Of Polyacrylamide (Pam) Effects On Irrigation Efficiency, Soil Conservation, And Water Quality In Midsouth Cotton Production, Brittany D. Barnes

Student Theses and Dissertations

The polymer, polyacrylamide (PAM), is a high molecular weight, chemical anionic polymer that is prescribed and used for irrigation improvement in row crops primarily in the United States. A field research study was conducted in 2014, 2015 and 2016 in Northeast Arkansas to evaluate how addition of PAM in furrow irrigation affected soil erosion, water infiltration, movement of nutrients and sediments, and crop yields in cotton (Gossypium hirsutum). Overall results from the study were mixed. Sediment loss was similar among treatments. Irrigation advancement rates were not significantly different. No differences in crop yield were observed associated with PAM. Differences in …

Natural Variation In Host Feeding Behaviors Impacts Host Disease And Pathogen Transmission Potential, Alaina C. Pfenning-Butterworth, Rachel E. Vetter, Jessica L. Hite

School of Biological Sciences: Faculty Publications

Animals ranging from mosquitoes to humans often vary their feeding behavior when infected or merely exposed to pathogens. These so-called “sickness behaviors” are part of the innate immune response with many consequences, including avoiding orally transmitted pathogens. Fully understanding the role of this ubiquitous behavior in host defense and pathogen evolution requires a quantitative account of its impact on host and pathogen fitness across environmentally relevant contexts. Here, we use a zooplankton host and fungal pathogen as a case study to ask if infection-mediated feeding behaviors vary across pathogen exposure levels and natural genetic variation in susceptibility to infection. Then, …

The Grizzly, February 9, 2023, Layla Halterman, Chase Portaro, Marie Sykes, Jagger Clapsadle, Erin Corcoran, Kate I. Foley, Isabel Wesman, Ava Compagnoni

Ursinus College Grizzly Newspaper, 1978 to Present

The Wismer Shuffle • Talking Trash to Address Ursinus' Waste Issue • February Editor's Letter • Ursinus Student Lives It Up, Down Under • Job, Internship and Networking Fair February 15! • Opinions: Pets Banned From Campus Buildings? A-Paw-lling! • "Deal"-ing out Ws • Swim, Swam, Swum in Florida

Deep Seabed Mining Lacks Social Legitimacy, A Jaeckel, H Harden-Davies, Dj Amon, Der Grient J Van, Q Hanich, Leeuwen J Van, Hj Niner, Katherine Seto

School of Biological and Marine Sciences

IntroductionThe technology to mine the ocean floor for valuable minerals such as copper, nickel, and cobalt is currently being developed. Scientists have warned repeatedly about potentially serious and irreversible environmental impacts from deep seabed mining (DSM), including but not limited to: removal and destruction of sensitive and poorly known seafloor habitats and species; metal-contaminated and fine-particle sediment plumes that can impact benthic and pelagic fauna; changes to water properties; and increases in noise and light1,2. What remains to be substantially debated are the social impacts of DSM.

Tobacco Exposure In Adults And Children With Proteinuric Glomerulopathies: A Neptune Cohort Study., Linda Wang, Bayle Smith-Salzberg, Kevin Ec Meyers, Dorey A. Glenn, Katherine R. Tuttle, Vimal K. Derebail, Tammy M. Brady, Keisha Gibson, Abigail R. Smith, Michelle M. O'Shaughnessy, Tarak Srivastava, Gentzon Hall, Jarcy Zee, Markus Bitzer, Christine B. Sethna

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Tobacco exposure has been recognized as a risk factor for cardiovascular disease (CVD) and progression of kidney disease. Patients with proteinuric glomerulopathies are at increased risk for cardiovascular morbidity and mortality. Multiple studies have linked tobacco exposure to CVD and chronic kidney disease, but the relationships between smoking and proteinuric glomerulopathies in adults and children have not been previously explored.

METHODS: Data from the Nephrotic Syndrome Study Network (NEPTUNE), a multi-center prospective observational study of participants with proteinuric glomerulopathies, was analyzed. 371 adults and 192 children enrolled in NEPTUNE were included in the analysis. Self-reported tobacco exposure was classified …

Splicing Factor Srsf1 Deficiency In The Liver Triggers Nash-Like Pathology And Cell Death, Waqar Arif, Bhoomika Mathur, Michael F Saikali, Ullas V Chembazhi, Katelyn Toohill, You Jin Song, Qinyu Hao, Saman Karimi, Steven M Blue, Brian A Yee, Eric L Van Nostrand, Sushant Bangru, Grace Guzman, Gene W Yeo, Kannanganattu V Prasanth, Sayeepriyadarshini Anakk, Carolyn L Cummins, Auinash Kalsotra

Faculty, Staff and Students Publications

Regulation of RNA processing contributes profoundly to tissue development and physiology. Here, we report that serine-arginine-rich splicing factor 1 (SRSF1) is essential for hepatocyte function and survival. Although SRSF1 is mainly known for its many roles in mRNA metabolism, it is also crucial for maintaining genome stability. We show that acute liver damage in the setting of targeted SRSF1 deletion in mice is associated with the excessive formation of deleterious RNA-DNA hybrids (R-loops), which induce DNA damage. Combining hepatocyte-specific transcriptome, proteome, and RNA binding analyses, we demonstrate that widespread genotoxic stress following SRSF1 depletion results in global inhibition of mRNA …

Shoulder Muscle Activity While Swimming In Different Wetsuits And Across Different Paces, Boram Lim, Alina P. Swafford, Katelyn E. Conroy, John A. Mercer

International Journal of Exercise Science

International Journal of Exercise Science 16(1): 172-181, 2023. A triathlon wetsuit is an important piece of equipment during the swim portion of the triathlon for the benefits of thermoregulation and additional buoyancy. However, a lack of knowledge exists about whether or not shoulder muscle activity is influenced by wearing a wetsuit. The purpose of this study was to determine if there were changes in shoulder muscle activity during front crawl with four different wetsuit conditions: Full sleeve (FSW), Sleeveless (SLW), Buoyancy shorts (BS), No wetsuit (NWS) in three different subjective swimming paces (slow, medium, and fast). Eight subjects (5 males, …

Sustainability Of Traditional Retail In An Emerging Market: A Conceptual Framework Applied To A Vietnamese Wet Market, Thi Tuyet Nhung Tran

Asia Marketing Journal

In emerging countries, traditional retail, such as wet markets, still accounts for a large proportion of retail sales. Traditional retail has poor infrastructure compared to modern retail, and is often associated with problems of waste, water, and environmental pollution. Therefore, traditional retail faces extreme difficulties in achieving sustainability. This study aimed to determine what value traditional retail contributes to sustainability. We generated and applied a conceptual framework of sustainability to explore this question. We used a single case study of a small-scale wet market in Vietnam. The results showed that wet markets have significant value for the development of sustainable …

An Updated Classification Of Meditation Methods Using Principles Of Taxonomy And Systematics, Jonathan D. Nash, Andrew B. Newberg

Marcus Institute of Integrative Health Faculty Papers

This paper revisits the proposal for the classification of meditation methods which we introduced in our initial 2013 publication, “Toward a Universal Taxonomy and Definition of Meditation”. At that time, we advanced the thesis that meditation methods could be effectively segregated into three orthogonal categories by integrating the taxonomic principle of functional essentialism and the paradigm of Affect and Cognition; and we presented relevant research findings which supported that assertion. This iteration expands upon those theoretical and methodological elements by articulating a more comprehensive Three Tier Classification System which accounts for the full range of meditation methods; and demonstrates how …

Early Nutritional Education: The Key To Success, Riley A. Gerbereux

CAFE Symposium 2023

For my project I researched and interviewed countless sources about the importance of nutritional education and how it can be included in the Gettysburg community. I then created a plan that works to implement a nutrition program once a month in El Centro that educates kids about proper healthy habits and provides a nutritious snack.

Editorial: Community Series In Research Efforts, Challenges And Opportunities In Mitigating Aflatoxins In Food And Agricultural Crops And Its Global Health Impacts, Volume Ii, Mehdi Razzaghi-Abyaneh, Zhi Yuan Chen, Mahendra Rai, Masoomeh Shams-Ghahfarokhi

Faculty Publications

No abstract provided.

Gamerfit-Asd Beta Test: Adapting An Evidence-Based Exergaming And Telehealth Coaching Intervention For Autistic Youth, Daniel P. Hatfield, Aviva Must, Winston Kennedy, Amanda E. Staiano, James Slavet, Rachael A. Sabelli, Carol Curtin, Linda G. Bandini, Phillip Nauta, Christopher Stuetzle, April B. Bowling

Population and Public Health Science Faculty Publications

Background: Health disparities faced by autistic youth are exacerbated by inadequate physical activity (PA) and sleep, whereas healthy PA and sleep may improve mood and function. Adaptive Game Squad (AGS) is an evidence-based telehealth coaching and exergaming intervention to improve PA and sleep for adolescents with diverse neurodevelopmental and psychiatric conditions. This study aimed to adapt AGS for autistic youth ages 10–15 years; beta-test the modified intervention for feasibility, accessibility, and engagement; and further refine the intervention for a larger planned demonstration pilot. Methods: Interdisciplinary experts adapted AGS to create GamerFit-ASD, a 12-week intervention that included a progressive exergame schedule, …

Combination Sodium Nitrite And Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity In A “2-Hit” Murine Model, Kyle B. Lapenna, Zhen Li, Jake E. Doiron, Thomas E. Sharp, Huijing Xia, Karl Moles, Kashyap Koul, John S. Wang, David J. Polhemus, Traci T. Goodchild, Ravi B. Patel, Sanjiv J. Shah, David J. Lefer

School of Medicine Faculty Publications

BACKGROUND: Recent studies have suggested that cardiac nitrosative stress mediated by pathological overproduction of nitric oxide (NO) via inducible NO synthase (iNOS) contributes to the pathogenesis of heart failure with preserved ejection fraction (HFpEF). Other studies have suggested that endothelial NO synthase (eNOS) dysfunction and attenuated NO bioavailability contribute to HFpEF morbidity and mortality. We sought to further investigate dysregulated NO signaling and to examine the effects of a NO-based dual therapy (sodium nitrite+hydralazine) following the onset of HFpEF using a “2-hit” murine model. METHODS AND RESULTS: Nine-week-old male C57BL/6 N mice (n=15 per group) were treated concurrently with high-fat …

Providing Optimal Nutritional Care To Patients With Long-Covid, Hernández Ya Tronco, L Anderson, L Weekes, A Julian, J Murphy, G Frost, M Hickson

School of Health Professions

Long-COVID has emerged as a relatively common condition with symptoms that vary considerably in intensity and type. People with long-COVID experience signs and symptoms that develop during or after an infection consistent with coronavirus disease 2019 (COVID-19), continue for more than four weeks and are not explained by an alternative diagnosis. It has been estimated that up to one in seven patients who have COVID-19 will have long-COVID. Long-COVID can affect people’s nutritional status, while optimal nutrition is essential for their recovery. The authors of this article have developed an evidence-based knowledge hub around nutrition and recovery from COVID-19 that …

Association Between Feelings Of Trust And Security With Subjective Health Among Mexican Migrants In The New York City Area, Pablo Gaitán-Rossi, Mireya Vilar-Compte, Isabel Ferré-Eguiluz, Luis Ortiz, Erika Garcia

Department of Public Health Scholarship and Creative Works

The size of the foreign-born population living in the United States makes migrants’ health a substantive policy issue. The health status of Mexican immigrants might be affected by the level of social capital and the social context, including the rhetoric around immigration. We hypothesize that a diminished perception of trust and safety in the community has a negative impact on self-reported health. In a cross-sectional study, we conducted a survey among 266 Mexican Immigrants in the New York City Area who used the Mexican Consulate between May and June 2019 for regular services provided to documented and undocumented immigrants. A …

Factors Influencing Dietetic Interns' Dietary Habits During Supervised Practice, Courtney Weese, Katie M. Thompson, Adalyn White, Brianne Oronoz, Karli Breinholt, Dawson V. Croxall, Kelzie Devitt, Marin Easton, Madison L. Gunter, Breann Mcfarlane, Kaitlyn Reich, Jenna Sacks, Lacie Peterson, Rebecca Charlton, Holly Hopkins, Katie N. Kraus

Nutrition, Dietetics, and Food Science Student Research

Supervised practice is a prerequisite to becoming a registered dietitian. Research suggests that environmental and social factors may affect dietary choices. This focus group research aimed to gather opinions from dietetic interns to understand what factors related to supervised practice, if any, affected their dietary habits. Qualitative data were collected via seven recorded virtual focus groups in which trained moderators facilitated a discussion using a series of controlled questions. Participants, dietetic interns (n = 42) who were currently completing or had completed their supervised practice within the previous six months, attended one of seven virtual focus groups. Each focus …

Hepatocytes Demarcated By Ephb2 Contribute To The Progression Of Nonalcoholic Steatohepatitis, Yang Xiao, Kirill Batmanov, Wenxiang Hu, Kun Zhu, Alexander Y Tom, Dongyin Guan, Chunjie Jiang, Lan Cheng, Sam J Mccright, Eric C Yang, Matthew R Lanza, Yifan Liu, David A Hill, Mitchell A Lazar

Faculty, Staff and Students Publications

Current therapeutic strategies for treating nonalcoholic steatohepatitis (NASH) have failed to alleviate liver fibrosis, which is a devastating feature leading to hepatic dysfunction. Here, we integrated single-nucleus transcriptomics and epigenomics to characterize all major liver cell types during NASH development in mice and humans. The bifurcation of hepatocyte trajectory with NASH progression was conserved between mice and humans. At the nonalcoholic fatty liver (NAFL) stage, hepatocytes exhibited metabolic adaptation, whereas at the NASH stage, a subset of hepatocytes was enriched for the signatures of cell adhesion and migration, which were mainly demarcated by receptor tyrosine kinase ephrin type B receptor …

Bnt162b2 Mrna Vaccination Against Coronavirus Disease 2019 Is Associated With A Decreased Likelihood Of Multisystem Inflammatory Syndrome In Children Aged 5-18 Years-United States, July 2021 - April 2022, Laura D Zambrano, Margaret M Newhams, Samantha M Olson, Natasha B Halasa, Ashley M Price, Amber O Orzel, Cameron C Young, Julie A Boom, Leila C Sahni, Aline B Maddux, Katherine E Bline, Satoshi Kamidani, Keiko M Tarquinio, Kathleen Chiotos, Jennifer E Schuster, Melissa L Cullimore, Sabrina M Heidemann, Charlotte V Hobbs, Ryan A Nofziger, Pia S Pannaraj, Melissa A Cameron, Tracie C Walker, Stephanie P Schwartz, Kelly N Michelson, Bria M Coates, Heidi R Flori, Elizabeth H Mack, Laura Smallcomb, Shira J Gertz, Samina S Bhumbra, Tamara T Bradford, Emily R Levy, Michele Kong, Katherine Irby, Natalie Z Cvijanovich, Matt S Zinter, Cindy Bowens, Hillary Crandall, Janet R Hume, Manish M Patel, Angela P Campbell, Adrienne G Randolph, Overcoming Covid-19 Investigators

Faculty, Staff and Students Publications

BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C), linked to antecedent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is associated with considerable morbidity. Prevention of SARS-CoV-2 infection or coronavirus disease 2019 (COVID-19) by vaccination might also decrease MIS-C likelihood.

METHODS: In a multicenter, case-control, public health investigation of children ages 5-18 years hospitalized from 1 July 2021 to 7 April 2022, we compared the odds of being fully vaccinated (2 doses of BNT162b2 vaccine ≥28 days before hospital admission) between MIS-C case-patients and hospital-based controls who tested negative for SARS-CoV-2. These associations were examined by age group, timing of vaccination, …

Incidence, Attributable Mortality, And Healthcare And Out-Of-Pocket Costs Of Clostridioides Difficile Infection In Us Medicare Advantage Enrollees, Holly Yu, Tamuno Alfred, Jennifer L Nguyen, Jingying Zhou, Margaret A Olsen

2020-Current year OA Pubs

BACKGROUND: US attributable Clostridioides difficile infection (CDI) mortality and cost data are primarily from Medicare fee-for-service populations, and little is known about Medicare Advantage Enrollees (MAEs). This study evaluated CDI incidence among MAEs from 2012 to 2019 and determined attributable mortality and costs by comparing MAEs with and without CDI occurring in 2018.

METHODS: This retrospective cohort study assessed CDI incidence and associated mortality and costs for eligible MAEs ≥65 years of age using the de-identified Optum Clinformatics Data Mart database (Optum; Eden Prairie, Minnesota, USA). Outcomes included mortality, healthcare utilization, and costs, which were assessed via a propensity score-matched …

Body Mass Index And Molecular Subtypes Of Colorectal Cancer, Neil Murphy, Yin Cao, Et Al.

2020-Current year OA Pubs

BACKGROUND: Obesity is an established risk factor for colorectal cancer (CRC), but the evidence for the association is inconsistent across molecular subtypes of the disease.

METHODS: We pooled data on body mass index (BMI), tumor microsatellite instability status, CpG island methylator phenotype status, BRAF and KRAS mutations, and Jass classification types for 11 872 CRC cases and 11 013 controls from 11 observational studies. We used multinomial logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CI) adjusted for covariables.

RESULTS: Higher BMI was associated with increased CRC risk (OR per 5 kg/m2 = 1.18, 95% CI = …