Digital Commons Network^™

The Association Of Intravitreal Injections Of Different Anti-Vascular Endothelial Growth Factor With Systemic Outcomes In Diabetic Patients, Eugene Yu-Chuan Kang, Tzu-Yi Lin, Sunir J. Garg, Nan-Kai Wang, Lee-Jen Chen, Pei-Wei Huang, Ming-Jen Chan, Kuan-Jen Chen, Wei-Chi Wu, Chi-Chun Lai, Yih-Shiou Hwang

Wills Eye Hospital Papers

This retrospective cohort study aimed to assess the systemic effects of three commonly available anti-vascular endothelial growth factor intravitreal injections in patients with diabetes, using data taken from a multi-institutional database in Taiwan. Patient data were sourced from the multi-institutional Chang Gung Research Database. Participants were divided into groups based on treatment with bevacizumab, ranibizumab, or aflibercept. Baseline characteristics were matched among the groups by the inverse probability of treatment weighting. The incidence rate of outcome events was calculated as the number of events divided by 100 person-years of follow-up. The cumulative incidence function was used to estimate the incidence …

The Association Between Medication Use In Older Women With Early-Stage Operable Primary Breast Cancer And Decision Regarding Primary Treatment, Natalie Tse, Ruth M Parks, Holly M Holmes, Kwok-Leung Cheung

Faculty, Staff and Student Publications

Background: Polypharmacy is one factor contributing to increased mortality, hospitalization, and adverse drug reactions in older adults. The aim of this study was to measure the prevalence of polypharmacy in a cohort of older women with early-stage operable primary breast cancer and the relationship of polypharmacy to primary treatment decision and functional status.

Methods: A total of 139 patients with a new diagnosis of early-stage operable primary breast cancer proven histologically were recruited as part of a prospective study. The average age was 77 years. Assessment using a cancer-specific Comprehensive Geriatric Assessment (CGA) tool was conducted within 6 weeks of …

Global Scientific Trends On Healthy Eating From 2002 To 2021: A Bibliometric And Visualized Analysis, Te Fang, Hongyi Cao, Yue Wang, Yang Gong, Zhongqing Wang

Faculty, Staff and Student Publications

Diet has been recognized as a vital risk factor for non-communicable diseases (NCDs), climate changes, and increasing population, which has been reflected by a rapidly growing body of the literature related to healthy eating. To reveal a panorama of the topics related to healthy eating, this study aimed to characterize and visualize the knowledge structure, hotspots, and trends in this field over the past two decades through bibliometric analyses. Publications related to healthy eating between 1 January 2002 and 31 December 2021 were retrieved and extracted from the Web of Science database. The characteristics of articles including publication years, journals, …

Protocols For Single-Cell Rna-Seq And Spatial Gene Expression Integration And Interactive Visualization, Surbhi Sona, Matthew Bradley, Angela H Ting

Faculty, Staff and Student Publications

There is a wealth of software that utilizes single-cell RNA-seq (scRNA-seq) data to deconvolve spatial transcriptomic spots, which currently are not yet at single-cell resolution. Here we provide protocols for implementing Seurat and Giotto packages to elucidate cell-type distribution in our example human ureter scRNA-seq dataset. We also describe how to create a stand-alone interactive web application using Seurat libraries to visualize and share our results. For complete details on the use and execution of this protocol, please refer to Fink et al. (2022).

Effects Of The Ketogenic Diet On Spatial Memory And Long-Term Potentiation In The Ca1 Region Of The Hippocampus In Young Rodents, Jed Christensen

Undergraduate Honors Theses

The ketogenic diet (KD) originated as a treatment for epilepsy nearly a century ago, though its neurological effects are not completely understood. In recent years the diet has resurged as a weight loss aid, reinvigorating research investigating its effects on the nervous system. Notably, the KD alters the concentration of glucose and ketones in the brain, and recent research suggests that the elevated ketone concentration, in the form of beta-hydroxybutyrate, induced by the diet enhances recognition memory and mitochondrial efficiency in the hippocampus. To further explore the effects of the KD, we examined its cognitive effects on spatial memory and …

Mujeres Latinas En Acción: Pragmatic Feminism And The Longevity Of Grassroots Organizations, Lindsey Meza

Undergraduate Honors Theses

In 1973, Mujeres Latinas en Acción was formed in the midst of the Chicano Movement. Simultaneously, Chicana feminists were working in and breaking from Chicano organizations to fight for egalitarian gains. Pilsen, a neighborhood in Chicago and the home of Mujeres Latinas en Acción, was a hotbed for Chicano and Latino activism during this period. The women who founded MLEA saw similar disparities in social services offered to women in Pilsen that Chicanas around the country were noting. The ways in which Chicanas were approaching these feminist ventures varied. Based upon my studies of Mujeres Latinas en Acción, I argue …

March 17, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Cyanobacteria And Algal-Based Biological Life Support System (Blss) And Planetary Surface Atmospheric Revitalizing Bioreactor Brief Concept Review, Ryan Keller, Karthik Goli, William Porter, Aly Alrabaa, Jeffrey A Jones

Faculty, Staff and Students Publications

Exploring austere environments required a reimagining of resource acquisition and utilization. Cyanobacterial in situ resources utilization (ISRU) and biological life support system (BLSS) bioreactors have been proposed to allow crewed space missions to extend beyond the temporal boundaries that current vehicle mass capacities allow. Many cyanobacteria and other microscopic organisms evolved during a period of Earth's history that was marked by very harsh conditions, requiring robust biochemical systems to ensure survival. Some species work wonderfully in a bioweathering capacity (siderophilic), and others are widely used for their nutritional power (non-siderophilic). Playing to each of their strengths and having them grow …

Vol.50 N.34 March 16th 2023, Voice Media Ventures

Black Voice News

No abstract provided.

Narrative Review: The Fda’S Perfunctory Approach Of Dietary Supplement Regulations Giving Rise To Copious Reports Of Adverse Events, Weiqi Li, Albert Wertheimer

HPD Articles

Background: The Food and Drug Administration (FDA) originated from the passage of the 1906 Pure Food and Drugs act aimed to rein in the long-standing abuse in the consumer product marketplace. The act was passed to prohibit interstate commerce of misbranded and adulterated foods, drinks, drugs. Thus, promoting the FDA’s mission to protect the public health by regulating human and veterinary drugs, biological products, medical devices, food supply, cosmetics, and tobacco to ensure safety, efficacy, and security. Progressing further in 1994, the Dietary Supplement Health and Education Act (DSHEA) was established designating specific label requirements, providing regulatory framework, and authorizing …

College Student Food Security During The Covid-19 Pandemic, Frances Rafferty, Tania Schusler, Mariana Valencia Mestre

School of Environmental Sustainability: Faculty Publications and Other Works

Food insecurity among college and university students has increased in the past decade. The COVID-19 pandemic has presented unique public health challenges, including increased food insecurity. In a cross-sectional survey of students at a private university in the midwestern U.S. (N=253) we examined how student food security status changed during the pandemic and what relation-ships exist between changes in food security and various aspects of student identities. Twenty-nine percent of responding students indicated that they became less food secure during the pandemic, and the overall reported food insecurity rate increased by 130.77%. Change in respondent food security status during the …

Application Of Convergent Science And Technology Toward Ocular Disease Treatment, Ayca Bal-Ozturk, Ece Ozcan-Bulbul, Hazal Ezgi Gultekin, Berivan Cecen, Ebru Demir, Atefeh Zarepout, Sibel Cetinel, Ali Zarrabi

Henry M. Rowan College of Engineering Departmental Research

Eyes are one of the main critical organs of the body that provide our brain with the most information about the surrounding environment. Disturbance in the activity of this informational organ, resulting from different ocular diseases, could affect the quality of life, so finding appropriate methods for treating ocular disease has attracted lots of attention. This is especially due to the ineffectiveness of the conventional therapeutic method to deliver drugs into the interior parts of the eye, and the also presence of barriers such as tear film, blood-ocular, and blood-retina barriers. Recently, some novel techniques, such as different types of …

The Current - Volume 33 Issue 7, Nova Southeastern University

Student Newspapers

No abstract provided.

Monkeypox Proctitis: A Case Of Targeted Treatment With Tecovirimat., Premalkumar Patel, Cynthia Espinosa, Varsha Konyala, Nicholas S. Camps, Estafenia Cecilio, Aakangsha Jain, Claudio Tuda

HPD Articles

Monkeypox (MPX) is an exanthematous disease first identified in the 1950s, associated with animals in Central and Western Africa, and has since been found sporadically worldwide. In May 2022, a returning family from Nigeria tested positive for MPX, which marked the onset of the current outbreak. It has now become a disease of concern in most parts of the world. The current standings are nearing 90,000 cases, with numbers increasing daily. The United States reported 29,711 cases so far. The characteristic exanthem of MPX is known to be present ubiquitously on the human habitus, with recent reports describing anogenital and …

Young Adult Cancer Patients And Survivors’ Adherence To Healthy Eating And Physical Activity Guidelines, Sandra Soca Lozano

USF Tampa Graduate Theses and Dissertations

Many Adolescents and Young Adult (AYA) cancer patients/survivors do not engage in healthy eating and physical activity recommendations. The present study assessed the role of race/ethnicity, health literacy, and home environmental influences and its association with adherence to healthy eating and physical activity. AYA patients/survivors from Moffitt Cancer Center (n = 273) completed an anonymous online survey. Self-reported measures about eating habits, physical activity, health literacy, and social support were used. Black/African Americans reported worse eating habits than White and Hispanic participants. Obese participants showed a similar trend compared to all other Body Mass Index groups. Adherence to physical activity …

Impact Of Food Distribution Sites In Rural Neighborhoods At Risk For Food Insecurity In San Bernardino County, Lydia Garcia-Usry

Dissertations

Food security is an important element in the lifespan of individuals, and access to healthy food is important to the quality of life in communities. The significance of food insecurity is reflective of a community that does not have the resources to provide a consistent and stable intake of healthy and nutritious meals. Food insecurity has been linked to chronic illnesses such as heart disease, diabetes, hypertension, obesity, and the level of poverty in a community. The United States of America reports that 50 million people suffer from food insecurity, and it is reported as an urgent public health problem. …

Allocation Of U.S. Biomass Production To Food, Feed, Fiber, Fuel And Exports, Christopher L. Lant, Suman Paudel, Kaeli Mueller, Grace Larson, Gustavo A. Ovando-Montejo, Jennifer E. Givens

Environment and Society Faculty Publications

This paper analyzes the end uses—food, feed, fiber, fuel, and exports—of biomass production in the U.S. in 1997, 2002, 2007, and 2012. They are also analyzed at the state level in 2012. Biomass production is measured as human appropriation of net primary production (HANPP), an ecological footprint measured as carbon fixed through photosynthesis, derived from data on crop, timber and grazing yields. HANPP was allocated to end uses using publicly available sources from the U.S. Department of Agriculture and internet-based sources publishing data on agricultural trade. HANPP was 717–834 megatons (MT) of carbon per year, which comprised 515–615 MT of …

How Have Researchers Defined Institutions, Politics, Organizations And Governance In Research Related To Epidemic And Pandemic Response? A Scoping Review To Map Current Concepts, Austin Wu, Shivangi Khanna, Shelly Keidar, Peter Berman, Laura Jane Brubacher

Faculty, Staff and Student Publications

In recent years, the literature on public health interventions and health outcomes in the context of epidemic and pandemic response has grown immensely. However, relatively few of these studies have situated their findings within the institutional, political, organizational and governmental (IPOG) context in which interventions and outcomes exist. This conceptual mapping scoping study synthesized the published literature on the impact of IPOG factors on epidemic and pandemic response and critically examined definitions and uses of the terms IPOG in this literature. This research involved a comprehensive search of four databases across the social, health and biomedical sciences as well as …

Evaluating Sensory Quality, Willingness To Try, Risk And Product Appropriateness Of Seafood Byproducts, Silvia Jessenia Murillo Miguez

LSU Master's Theses

Valorization of food wastes/byproducts has become a major subject of research to increase sustainability of the global food supply chain. Seafood industries generate a substantial quantity of byproducts. An online survey was used to evaluate Willingness-to-try (WTT), the effect of a Consumer Safety Statement (CSS) on WTT, perceived risks and product appropriateness associated with seafood byproducts in food as influenced by gender and race. Based on the finding from this survey, a clean label catfish bone powder (CBP) was developed and used for breaded catfish sticks which were evaluated for sensory liking, emotional profile, and purchase intent. Previous consumers of …

Factors That Led To Crossing The Picket-Line: An Autoethnography Of A Faculty Striker, Giovanna Follo

Journal of Collective Bargaining in the Academy

Historically, academic strikes are not frequent and are short. Much of the research examines why academic strikes occur; however, few explore the individual multidimensional striker. The research question in this autoethnographic essay explored, “What factors led me, a pro-union advocate, to cross the picket line?” Crossing the picket meant going back to work before the strike was declared over. The self-reflexive narrative examines several themes, including the mental health burden of anxiety and stress, the place of coercive power used when the administration pursues extreme threats, the role that unions play in setting up expectations at the outset of a …

Soybean GmSaul1, A Bona Fide U-Box E3 Ligase, Negatively Regulates Immunity Likely Through Repressing The Activation Of GmMpk3, Jun-Mei Li, Mei-Yan Ye, Chaofeng Wang, Xiao-Han Ma, Ni-Ni Wu, Chen-Li Zhong, Yanjun Zhang, Ninghui Cheng, Paul A. Nakata, Lirong Zeng, Jian-Zhong Liu

Center for Plant Science Innovation: Faculty Publications

E3 ubiquitin ligases play important roles in plant immunity, but their role in soybean has not been investigated previously. Here, we used Bean pod mottle virus (BPMV)-mediated virusinduced gene silencing (VIGS) to investigate the function of GmSAUL1 (Senescence-Associated E3 Ubiquitin Ligase 1) homologs in soybean. When two closely related SAUL1 homologs were silenced simultaneously, the soybean plants displayed autoimmune phenotypes, which were significantly alleviated by high temperature, suggesting that GmSAUL1a/1b might be guarded by an R protein. Interestingly, silencing GmSAUL1a/1b resulted in the decreased activation of GmMPK6, but increased activation of GmMPK3 in response to flg22, …

Connecting Higher Education To Workplace Activities And Earnings, Hung Chau, Sarah H. Bana, Baptiste Bouvier, Morgan R. Frank

Economics Faculty Articles and Research

Higher education is a source of skill acquisition for many middle- and high-skilled jobs. But what specific skills do universities impart on students to prepare them for desirable careers? In this study, we analyze a large novel corpora of over one million syllabi from over eight hundred bachelors’ granting US educational institutions to connect material taught in higher education to the detailed work activities in the US economy as reported by the US Department of Labor. First, we show how differences in taught skills both within and between college majors correspond to earnings differences of recent graduates. Further, we use …

Diurnal Time-Activity Budget And Habitat Use Of Whooping Cranes (Grus Americana) In The Reintroduced Louisiana Nonmigratory Population, Phillip L. Vasseur, Sammy L. King, Michael D. Kaller

Faculty Publications

Time-activity budget studies provide valuable insights for better understanding animal behavior relative to spatial and temporal habitat use. We examined a reintroduced, nonmigratory Whooping Crane (Grus americana) population to determine how time-activity budgets change relative to crane age, sex, habitat type, and season. Our study area encompassed natural marshes and working wetlands primarily in southwestern Louisiana. From June 2012 to January 2016, we conducted continuous focal sampling on individuals (n = 27) from the first 4 captive-reared cohorts released in the state. We classified age groups as juveniles, subadults, and adults, and identified 5 main habitat types utilized by cranes …

An Ecological Systems Perspective On Individual Differences In Children's Performance On Measures Of Executive Function, Steven J. Holochwost, Deaven Winebrake, Eleanor D. Brown, Keith R. Happeney, Nicholas J. Wagner, W. Roger Mills-Koonce

Psychology Faculty Publications

The predictive validity of performance on cognitive-behavioral measures of executive function (EF) suggests that these measures index children's underlying capacity for self-regulation. In this paper, we apply ecological systems theory to critically evaluate this assertion. We argue that as typically administered, standard measures of EF do not index children's underlying, trait-like capacity for EF, but rather assess their state-like EF performance at a given point in time and in a particular (and often quite peculiar) context. This underscores the importance of disentangling intra-individual (i.e., state-like) and inter-individual (trait-like) differences in performance on these measures and understanding how factors at various …

Fresh Produce As A Potential Vector And Reservoir For Human Bacterial Pathogens: Revealing The Ambiguity Of Interaction And Transmission, Ahmed Esmael, Rashad R. Al-Hindi, Raed S. Albiheyri, Mona G. Alharbi, Amani A. R. Filimban, Mazen S. Alseghayer, Abdulaziz M. Almaneea, Meshari Ahmed Alhadlaq, Jumaa Ayubu, Addisu D. Teklemariam

Nebraska Center for Virology: Faculty Publications

The consumer demand for fresh produce (vegetables and fruits) has considerably increased since the 1980s for more nutritious foods and healthier life practices, particularly in developed countries. Currently, several foodborne outbreaks have been linked to fresh produce. The global rise in fresh produce associated with human infections may be due to the use of wastewater or any contaminated water for the cultivation of fruits and vegetables, the firm attachment of the foodborne pathogens on the plant surface, and the internalization of these agents deep inside the tissue of the plant, poor disinfection practices and human consumption of raw fresh produce. …

An Exploratory Study To Shape A Disaster Nurse Practitioner Scope Of Practice, Frances Dunniway

Dissertations

The impact and devastation from national disasters pose imminent risk to large populations. If trained in disaster response and following evidence-based practice standards, the Nurse Practitioner (NP) could be prepared to adapt to any setting or surrounding, utilizing their full educational and health care training. Currently there are no written guidelines during disasters to manage the various clinical conditions. Using a Delphi technique, this exploratory study investigated the multidisciplinary understanding about the disaster NP role. Key findings included: 1. Across four groups of disaster responders, there was confusion about the disaster NP role, indicating a need for role clarity. 2. …

Connectivity And Racial Equity In Responding To Covid-19 Impacts In The Chicago Regional Food System, Rowan Obach, Tania Schusler, Paulina Vaca, Sydney Durkin, Ma'raj Sheikh

School of Environmental Sustainability: Faculty Publications and Other Works

The COVID-19 outbreak led to major disruptions in food systems across the globe. In the United States’ Chicago region, the outbreak created immediate concerns around increased hunger, food insecurity, supply chain disruptions, and loss of local livelihoods. This was especially evident in communities of color, which faced disproportionate impacts from the pandemic. In March 2020, the Chicago Food Policy Action Council (CFPAC) coordinated a Rapid Response Effort that convened people in working groups related to emergency food assistance, local food producers, small businesses, and food system workers to address urgent needs that arose due to the pandemic. Each working group …

Safety Of Nivolumab Added To Chemoradiation Therapy Platforms For Intermediate And High-Risk Locoregionally Advanced Head And Neck Squamous Cell Carcinoma: Rtog Foundation 3504, Maura L Gillison, Robert L Ferris, Jonathan Harris, A Dimitrios Colevas, Loren K Mell, Christina Kong, Richard C Jordan, Kevin L Moore, Minh-Tam Truong, Claudia Kirsch, Arnab Chakravarti, Dukagjin M Blakaj, David A Clump, James P Ohr, John F Deeken, Michael F Gensheimer, Nabil F Saba, Jennifer A Dorth, David I Rosenthal, Rom S Leidner, Randall J Kimple, Mitchell Machtay, Walter J Curran, Pedro Torres-Saavedra, Quynh Thu Le

Faculty, Staff and Student Publications

PURPOSE: Programmed death-1 immune checkpoint blockade improves survival of patients with recurrent/metastatic head and neck squamous cell carcinoma (HNSCC), but the benefits of addition to (chemo)radiation for newly diagnosed patients with HNSCC remain unknown.

METHODS AND MATERIALS: We evaluated the safety of nivolumab concomitant with 70 Gy intensity modulated radiation therapy and weekly cisplatin (arm 1), every 3-week cisplatin (arm 2), cetuximab (arm 3), or alone for platinum-ineligible patients (arm 4) in newly diagnosed intermediate- or high-risk locoregionally advanced HNSCC. Patients received nivolumab from 2 weeks prior to radiation therapy until 3 months post-radiation therapy. The primary endpoint was dose-limiting …

Thresholds Of Quantitative Swallowing Measures Following Intensive Prophylactic Therapy In Head And Neck Cancer, Deirdre Larsen

LSU Doctoral Dissertations

This retrospective, case-controlled study sought to identify salient features of swallowing physiology in head and neck cancer (HNC) patients and the threshold for features associating with increased dysphagia severity or decreased functional status. Quantitative measures of videofluoroscopic swallow studies (VFSS) were taken during three graduating liquid boluses and a paste bolus. Fifteen HNC subjects that received high frequency swallowing exercises (2 - 5 weekly sessions) during (chemo)radiation were compared pre- and(n = 15) or normal (n = 15) swallowing. HNC subjects were also stratified to compare those attending only pre- and(n = 8) to those also returning with dysphagia complaints …

Information Needs Of Children Having A Radiology Technique: Imaging Centers, Rahele Mehrabi, Fatemeh Sheikhshoaei, Vahid Changizi, Nastaran Poursalehi, Farideh Pak, Mehrzad Mehdizadeh

IATUL 2023 Slides

No abstract provided.