Digital Commons Network^™

Homeobox Transcription Factor Hbxa Influences Expression Of Over One Thousand Genes In The Model Fungus Aspergillus Nidulans, Sandesh S. Pandit, Jinfang Zheng, Yanbin Yin, Sophie Lorber, Olivier Puel, Sourabh Dhingra, Eduardo A. Espeso, Ana M. Calvo

Department of Nutrition and Health Sciences: Faculty Publications

In fungi, conserved homeobox-domain proteins are transcriptional regulators governing development. In Aspergillus species, several homeobox-domain transcription factor genes have been identified, among them, hbxA/hbx1. For instance, in the opportunistic human pathogen Aspergillus fumigatus, hbxA is involved in conidial production and germination, as well as virulence and secondary metabolism, including production of fumigaclavines, fumiquinazolines, and chaetominine. In the agriculturally important fungus Aspergillus flavus, disruption of hbx1 results in fluffy aconidial colonies unable to produce sclerotia. hbx1 also regulates production of aflatoxins, cyclopiazonic acid and aflatrem. Furthermore, transcriptome studies revealed that hbx1 has a broad effect on the A. flavus …

College Students With Disabilities Are More Food Insecure, Nicholas Gosling

UNH Today Archive

No abstract provided.

Differential Effects Of Bariatric Surgery And Caloric Restriction On Hepatic One-Carbon And Fatty Acid Metabolism, Arnon Haran, Michael Bergel, Doron Kleiman, Liron Hefetz, Hadar Israeli, Sarah Weksler-Zangen, Bella Agranovich, Ifat Abramovich, Rachel Ben-Haroush Schyr, Eyal Gottlieb, Danny Ben-Zvi

Faculty, Staff and Student Publications

Weight loss interventions, including dietary changes, pharmacotherapy, or bariatric surgery, prevent many of the adverse consequences of obesity, and may also confer intervention-specific benefits beyond those seen with decreased weight alone. We compared the molecular effects of different interventions on liver metabolism to understand the mechanisms underlying these benefits. Male rats on a high-fat, high-sucrose diet underwent sleeve gastrectomy (SG) or intermittent fasting with caloric restriction (IF-CR), achieving equivalent weight loss. The interventions were compared to

The Red Ribbon And The Black Cross: A Qualitative Study Of The Relationship Between Social Activism And Contemporary Black Church Responses To Hiv In Oakland, Ca, Justise Wattree

McNair Research Journal SJSU

The Black Church as a social institution has been a source of social activism during racial crises, but there is a lacking social activist response by Black churches to HIV’s disparate impact on Black communities. Previous research does not adequately explore the influence of community-based organizations on Black church responses to HIV in the context of social activism. This study examines the relationship between social activism and contemporary Black church responses to HIV in Oakland. It considers community-based organizations (CBOs) as potential drivers of social activism. Semi-structured interviews with Black church leaders in Oakland were conducted and content analyzed along …

The Effects Of Exercise On The Mental Wellness Of Children (Ages 3-6), Reem Farhat

McNair Research Journal SJSU

When it comes to mental health, young children are often not researched and their tantrums or mood swings are not taken seriously, when in reality these small behavioral issues could be pointing to a larger issue. Children are the most overlooked when it comes to mental health diagnosis and treatment, unless the child begins to display extreme behavior (Philpott et al., 2019). However, preventative mental health care is arguably more pragmatic and less taboo than diagnosis and treatment. While there is research to support the use of exercise in mental wellness, there is still not enough done within the children …

Teaching Food Studies In Early College: Experiments In Collaboration, Cynthia Brown, Maryann Tebben

Early College Folio

This article outlines the process of designing and teaching a collaborative course on sustainable food and agriculture on multiple campuses at once, including two early college institutions. The authors offer insights on the specific elements of the course they designed as well as methods for designing the course, what worked in practice, and what they would change. This article will be useful for faculty who would like to work with other early college colleagues to plan a collaborative course in general or a specific course on sustainable food and farms.

Life, Death, And Recycling In The Homeric Simile, Briana Oser

Parnassus: Classical Journal

No abstract provided.

Parnassus Classical Journal (Volume 10, 2023), Parnassus Contributors

Parnassus: Classical Journal

No abstract provided.

Vol.50 N.52 July 20th 2023, Voice Media Ventures

Black Voice News

No abstract provided.

Clinical Practice Skills And Educational Resources For Managing Lymphedema, Grimes-Williams Lacinda

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.

Folic Acid Deficiency And Methylation In 3 Neurodegenerative Mouse Models: Dsp4-Alzheimer's, Down's Syndrome, And Aged, Jasmine Best, Antonio Gomez, Susan Helm

Summer Undergraduate Research in Biology Program

No abstract provided.

Clemson University Board Of Trustees, Finance And Facilities Committee, 2023 July 20, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson University Board Of Trustees, Full Board Minutes, 2023 July 20, Clemson University Board Of Trustees

Minutes

No abstract provided.

Plant Stem Undergraduate Symposium, David Britt

Biological Engineering Faculty Publications

No abstract provided.

Devoting Continuous Efforts To Innovations And Development Of Ruminant Livestock Life-Cycle Nutrition Program, Zhixiong He, Zhaomin Hu, Hongsheng Wang, Jinzhen Jiao, Xuefeng Han, Yong Liu, Shaoxun Tang, Chuanshe Zhou, Min Wang, Zhiliang Tan

Bulletin of Chinese Academy of Sciences (Chinese Version)

Ruminant livestock such as cattle and sheep can provide high-quality beef, mutton and milk, which are high-quality protein sources meeting the increasingly diverse food consumption needs for human being. Developing high-quality herbivorous animal husbandry is a concrete practice of practicing the “Greater Food” approach. The precise supply of forages and concentrates meeting the requirements of all nutrients in the whole life cycle is vital for cost saving and efficiency increasing of ruminant livestock industry, which is an important way to high-quality development. The whole life cycle nutrition is developed on the basis of traditional ruminant nutrition and new technologies made …

Cover 2

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Shared Treatment Decision Making On Hyperthyroidism Among Chinese Women Planning For Pregnancy, Feifei Gu

Electronic Theses and Dissertations Archive

Women of childbearing age are a high-risk group for hyperthyroidism. Although several hyperthyroidism treatment options are available, none are optimal. Women with hyperthyroidism planning to become pregnant may face the challenge of making a “trade-off” treatment decision for a future safe pregnancy. Shared treatment decision making (STDM) is an ideal model for physicians and patients to adopt in reaching an agreement and determining treatment decisions while considering the patient’s preferences, values, treatment costs and side effects. However, limited studies exist on STDM in women with hyperthyroidism before pregnancy. Therefore, this study aims to examine STDM on hyperthyroidism in Chinese women …

Engineered Reporter Phages For Detection Of Escherichia Coli, Enterococcus, And Klebsiella In Urine, Susanne Meile, Jonas Marschall, Et Al.

2020-Current year OA Pubs

The rapid detection and species-level differentiation of bacterial pathogens facilitates antibiotic stewardship and improves disease management. Here, we develop a rapid bacteriophage-based diagnostic assay to detect the most prevalent pathogens causing urinary tract infections: Escherichia coli, Enterococcus spp., and Klebsiella spp. For each uropathogen, two virulent phages were genetically engineered to express a nanoluciferase reporter gene upon host infection. Using 206 patient urine samples, reporter phage-induced bioluminescence was quantified to identify bacteriuria and the assay was benchmarked against conventional urinalysis. Overall, E. coli, Enterococcus spp., and Klebsiella spp. were each detected with high sensitivity (68%, 78%, 87%), specificity (99%, 99%, …

Editors - Mend, V.1, Mend Journal

Mend

No abstract provided.

Effects Of Childhood Health And Adversity On Women’S Estrous And Extended Sexuality In Romantic Relationships, Tran Dinh

Psychology ETDs

Variations in childhood conditions may favor different strategies of investment in pair-bonds and reproduction. The current study followed 213 romantically-involved women up to four times across the ovulatory cycle. Analyses find that childhood health and adversity moderate hormone-dependent changes in women’s sexual interests, oxytocin responses, and mate preferences. In light of proposed paternity assurance functions of extended (non-conceptive) sexuality, results suggest women with poorer, compared to better, childhood conditions prioritize bond formation but invest less in maintaining or bolstering partner investment. The estrous (conceptive) sexuality of women with poor childhood health may reflect greater investments in current reproduction, even when …

A Qualitative Study Of The Experiences Of Obesity, Body Image, And Mental Health Of British-Born Afro-Caribbean Male Students At A West Yorkshire University In England, Johnson Mbabazi, Dorothy Irene Nalweyiso, Fiona Macgregor, Jeff Breckon, Edward Kunonga, Barry Tolchard, Rosemary Dawson, Jennifer Teke, Josette Bettany Saltikov, George William Kagugube, Lawrence Achilles Nnyanzi

International Journal of Physical Activity and Health

Obesity, body image, and depression are all biopsychosocial phenomena that are frequently misunderstood across cultures. Body dissatisfaction is a psychological aspect of obesity that has been associated with disordered eating, low self-esteem, and depression. Nevertheless, body image dissatisfaction may affect non-obese individuals too. Those with a positive body image are more likely to participate in physical activity than those with a negative body image. Individuals who are satisfied with their body image are more likely to possess high self-esteem, confidence, and healthy eating habits. Obesity prevention among the black population is increasingly important. This study sought to examine the perceptions …

May Microbial Ecological Baseline Exist In Continental Groundwater?, Sining Zhong, Shungui Zhou, S Liu, Jiawen Wang, Chenyuan Dang, Qian Chen, Jinyun Hu, Shanqing Yang, Chunfang Deng, Wenpeng Li, J Liu, Alistair G.L. Borthwick, Jinren Ni

School of Engineering, Computing and Mathematics

Background Microbes constitute almost the entire biological community in subsurface groundwater and play an important role in ecological evolution and global biogeochemical cycles. Ecological baseline as a fundamental reference with less human interference has been investigated in surface ecosystems such as soils, rivers, and ocean, but the existence of groundwater microbial ecological baseline (GMEB) is still an open question so far. Results Based on high-throughput sequencing information derived from national monitoring of 733 newly constructed wells, we find that bacterial communities in pristine groundwater exhibit a significant lateral diversity gradient and gradually approach the topsoil microbial latitudinal diversity gradient with …

Id202 Oral History, Uniting Cultures

Uniting Cultures: Who We Are, How We Got Here: Collecting Stories Oral History Collection

A female of 2nd generation Welsh descent. Growing up on a farm in Le Sueur, she had saved money while working at Green Giant to go to school in Saint Paul where she would meet her husband through acquainted friends and went back to Mankato for a job. After marrying her husband, he got drafted into the Korean War and moved around the United States and eventually had their first child born in Alaska. They moved back to St. James on the family farm.

2023-July-18-Etsu Alumni Association Announces New Officers, Directors, University Marketing And Communication, East Tennessee State University

ETSU News

(July 18, 2023) A new slate of officers and directors will lead the ETSU National Alumni Association during the upcoming year.

Tom Tull, an MBA graduate from the East Tennessee State University Class of 1995, has been elected as president. Tull has over 30 years of health care experience and is a longtime member of the Ballad Health team, where he currently serves as vice president and chief experience officer.

Serving as president-elect is Dr. Virginia Bieber, a three-time graduate of ETSU whose degrees include an M.S. in clinical nutrition and an Ed.D. in educational leadership and policy …

Testing The Urban Dulling Hypothesis In An Iridescent Passerine Bird, Joanna Gresham

Master of Science in Integrative Biology Theses

Urbanization has brought grave consequences that lead to declines in many species; however, some species thrive in urban ecosystems. This allows us the opportunity to study evolution in real time, as species adapt and change in a new setting. Novel urban ecosystems have led to phenotypic divergence between urban and rural populations. There is a rich body of literature on how songbirds are affected by urbanization, however divergent signaling behaviors are less well understood. Urban color homogenization is well-documented in carotenoid-colored species. However, iridescent plumage is understudied in general, and little is understood about how environmental changes shape iridescent plumage. …

Editorial: Rising Stars In Microbial Physiology And Metabolism: 2022, Nicole R. Buan, Ulrike Kappler

Department of Biochemistry: Faculty Publications

This Research Topic was initiated to highlight work by young authors, the rising stars in the field of microbial physiology and metabolism. Microbial physiology and metabolism is an interdisciplinary field of research that seeks to uncover how the metabolic pathways of a cell work together to determine cell fate and function, whether that be growth, replication, pathogenicity, predation, respiration and fermentation, homeostasis or death. Ultimately, researchers like the ones featured here seek to integrate biological information and physicochemical parameters to try to find the underlying rules governing microbial function so that we can understand, predict and design microbes and microbial …

Abstracts From The 2023 Health Care Systems Research Network (Hcsrn) Annual Conference, Denver, Colorado

Journal of Patient-Centered Research and Reviews

The Health Care Systems Research Network (HCSRN) is comprised of 20 learning health systems with embedded population-based research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate project findings, explore scientific collaborations, and share insights about conducting research in real-world care delivery settings. Abstracts presented at HCSRN 2023 are published in this issue supplement of Journal of Patient-Centered Research and Reviews, the journal of record for HCSRN’s annual conference proceedings.

Integrating Genetics And Metabolomics From Multi-Ethnic And Multi-Fluid Data Reveals Putative Mechanisms For Age-Related Macular Degeneration, Xikun Han, Ines Lains, Jun Li, Jinglun Li, Yiheng Chen, Bing Yu, Qibin Qi, Eric Boerwinkle, Robert Kaplan, Bharat Thyagarajan, Martha Daviglus, Charlotte E Joslin, Jianwen Cai, Marta Guasch-Ferré, Deirdre K Tobias, Eric Rimm, Alberto Ascherio, Karen Costenbader, Elizabeth Karlson, Lorelei Mucci, A Heather Eliassen, Oana Zeleznik, John Miller, Demetrios G Vavvas, Ivana K Kim, Rufino Silva, Joan Miller, Frank Hu, Walter Willett, Jessica Lasky-Su, Peter Kraft, J Brent Richards, Stuart Macgregor, Deeba Husain, Liming Liang

Faculty, Staff and Student Publications

Age-related macular degeneration (AMD) is a leading cause of blindness in older adults. Investigating shared genetic components between metabolites and AMD can enhance our understanding of its pathogenesis. We conduct metabolite genome-wide association studies (mGWASs) using multi-ethnic genetic and metabolomic data from up to 28,000 participants. With bidirectional Mendelian randomization analysis involving 16,144 advanced AMD cases and 17,832 controls, we identify 108 putatively causal relationships between plasma metabolites and advanced AMD. These metabolites are enriched in glycerophospholipid metabolism, lysophospholipid, triradylcglycerol, and long chain polyunsaturated fatty acid pathways. Bayesian genetic colocalization analysis and a customized metabolome-wide association approach prioritize putative causal …

Nicu Culture Of Care For Infants With Neonatal Abstinence Syndrome: A Focused Ethnography, Monica M. Nelson

Dissertations

The purpose of this ethnographic study was to describe the culture of care and nonpharmacological nursing interventions performed by NICU nurses for infants with NAS.

Impact Of Mir196a-2 Genotypes On Colorectal Cancer Risk In Taiwan, Te-Cheng Yueh, Yun-Chi Wang, Yu-Ting Chin, Yi-Chih Hung, Mei-Chin Mong, Ya-Chen Yang, Jen-Sheng Pei, Jian Gu, Chia-Wen Tsai, Da-Tian Bau, Wen-Shin Chang

Faculty, Staff and Student Publications

We aimed to investigate the association between genotypes for