Digital Commons Network^™

Lead Acetate Deteriorates The Improvement Effect Of L-Arginine And Tetrahydrobiopterin On Endothelin-1 Receptors Activity In Rat Aorta, Zhikal Omar Khudhur, Ismail Mustafa Maulood

Baghdad Science Journal

Endothelin-1 (ET-1) is a potent vasoconstrictor hormone that has been identified as an important factor responsible for the development of cardiovascular dysfunctions. ET-1 exerts its vasoconstrictor activity through two pharmacologically distinct receptors, ETA and ETB that are found in vascular smooth muscle cells (VSMCs) and the vasodilator activity through an ETB receptor located on endothelial cells. This study aimed to show the impact of 1µM L-arginine (LA), 100µM tetrahydrobiopterin (BH4), and their combined effect on ET-1 activity in both lead-treated and lead-untreated rat aortic rings. This means, investigating how endothelial dysfunction reverses the role of nitric oxide precursor and cofactor. …

Quercetin In Sports And Exercise: A Review, Jennifer Kurtz, Trisha Vandusseldorp, Jeff Otis

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 1334-1384, 2023. This paper systematically reviews the latest evidence regarding Quercetin’s (Q) effect following exercise performance, aerobic and anaerobic exercise, muscle-damaging bouts and highlights blood biomarkers associated with muscle damage and recovery. Google Scholar, Web of Science, and MedLine (PubMed) searches were conducted through July- December 2021. Peer-reviewed studies that investigated Q as a single ingredient or in combination with other ingredients at dosages of 500 mg - 3000 mg, ranging from 15 min-to-1 h prior to exercise bout or chronic dose (7 days - 8 weeks) of consumption were included. A total of …

Establishing A Culture Of Assessment In A New Us Pharmacy School: Lessons Learned, Mohammed A. Islam, Suhui Yang

Health Professions Education

Purpose: This article describes the development and implementation of an assessment culture in a US pharmacy school, highlighting the associated challenges. Method: The school employed various strategies to foster an assessment culture, including meticulous planning, analyzing best practices, providing resources and financial support, and ensuring stakeholder participation. Faculty and staff received training and professional development, and an assessment committee was formed to oversee the implementation process. The committee's role was to utilize assessment results for decision-making and improving student learning outcomes. Regular feedback and progress reports were provided to stakeholders to ensure a smooth and efficient assessment process. Results: Effective …

School Of Culinary Arts & Food Technology Autumn Newsletter 2023, James Murphy

Other resources

The School of Culinary Arts and Food Technology, TU Dublin, Autumn Edition Newsletter captured the many events, research, awards, significant contributions and special civic and community activities which the students and staff members of the school have successfully completed up to the Autumn period of 2023. The successful completion of these activities would not be possible without the active and on-going support of the 'INSPIRED' friends of Culinary Arts (school supporters) and our school's industry association supporters. If you would like to support our school and the next Generation of Food, Culinary and Horticulture students, contact us at e: [email protected]

Presentation - Scaft School Awards Ceremony 2023, James Murphy

Other resources

This presentation captured the School of Culinary Arts & Food Technology, TU Dublin Awards Ceremony 2023 held in the Central Quad building on it's Grangegorman Campus, Dublin 7. The awards ceremony celebrate the magnificent achievements of the students and staff across their professional practice, new publications, research, National and International competitions, seminars, conferences and community engagement. These achievements would not be possible without the active and ongoing support of the school's sponsors (who are highlighted in this presentation). The school also remembers colleagues, students and industry figures who sadly passed away in the last year. If you interested in supporting …

Nanorobots, Genetic Testing, Better Lasers - A Kidney Stone Pioneer Looks To The Future, Matt Windsor

Browse All News

No abstract provided.

Assessing The Drivers Of Plastic Pollution On The Lagos Coastline : Strategies For Effective Policy Implementation And Mitigation, Clement Oshiobugie Orbih

World Maritime University Dissertations

No abstract provided.

An Evaluation Of The Alignment Of Liberian Fisheries Laws With Relevant International Legal Instruments To Combat Iuu Fishing In The Exclusive Economic Zone And Territorial Sea, Kla-Edward, Ii Toomey

World Maritime University Dissertations

No abstract provided.

Implementation Of Policies In Addressing Illegal, Unreported, And Unregulated (Iuu) Fishing In The Philippines : A Reappraisal Of Established Mechanisms, Jethro R. Padama

World Maritime University Dissertations

No abstract provided.

Combating Illegal, Unreported And Unregulated (Iuu) Fishing In Ecuador : : The Maritime Authority Approach For The Exercise Of Coastal State Rights, Daniela Andrade Tamayo

World Maritime University Dissertations

No abstract provided.

Advances In Molecular Pathology, Diagnosis, And Treatment Of Amyotrophic Lateral Sclerosis., Hristelina Ilieva, Mithila Vullaganti, Justin Kwan

Farber Institute for Neuroscience Faculty Papers

Although the past two decades have produced exciting discoveries in the genetics and pathology of amyotrophic lateral sclerosis (ALS), progress in developing an effective therapy remains slow. This review summarizes the critical discoveries and outlines the advances in disease characterization, diagnosis, imaging, and biomarkers, along with the current status of approaches to ALS care and treatment. Additional knowledge of the factors driving disease progression and heterogeneity will hopefully soon transform the care for patients with ALS into an individualized, multi-prong approach able to prevent disease progression sufficiently to allow for a dignified life with limited disability.

Tom Dusbiber, Oral History Interview, 2023, Finn Vincent-Fix, Matt Jones

Oral Histories

Thomas Dusbiber attended the Roosevelt School from Kindergarten in 1954 until he graduated in 1966. In this interview, Tom recounts his time at Roosevelt, talking about the quality of the teachers, the struggles of high school athletics, and where the popular hangout spots were when he was in school. He also explores the legacy of the school, and the reasons why so many former students remember it so fondly.

Leucine Supplementation Exacerbates Morbidity In Male But Not Female Mice With Colorectal Cancer-Induced Cachexia, Eleanor R. Schrems, Wesley S. Haynie, Richard A. Perry Jr., Francielly Morena, Ana Regina Cabrera, Megan E. Rosa-Caldwell, Nicholas P. Greene, Tyrone A. Washington

Health, Human Performance and Recreation Faculty Publications and Presentations

Cancer cachexia (CC) is a multifactorial wasting syndrome characterized by a significant loss in lean and/or fat mass and represents a leading cause of mortality in cancer patients. Nutraceutical treatments have been proposed as a potential treatment strategy to mitigate cachexia-induced muscle wasting. However, contradictory findings warrant further investigation. The purpose of this study was to determine the effects of leucine supplementation on skeletal muscle in male and female Apc^Min/+ mice (APC). APC mice and their wild-type (WT) littermates were given normal drinking water or 1.5% leucine-supplemented water (n = 4–10/group/sex). We measured the gene expression of regulators of …

A Text Analytics Model For Agricultural Knowledge Discovery And Sustainable Food Production: A Case Study From Oklahoma Panhandle, Ali Bagheri, Saleh Taghvaeian, Dursun Delen

Department of Agricultural and Biological Systems Engineering: Faculty Publications

With recent increases in the use of social media in agricultural communities, many farmers are showing more and more interest in participating in social media and sharing different aspects of their profession with peers and policymakers. However, researchers have not explored this valuable data source well enough to help improve agribusiness decision-making. This study aims to investigate the potential capability and richness of social media for agricultural knowledge discovery, which can help monitor, detect, and predict critical agricultural events and activities and develop more sustainable food production and agricultural economy. This research utilizes text-mining tools and techniques to collect, process, …

Association Of Residual Feed Intake To Metrics Of Tanganyika Shorthorn Zebu Cattle In Maswa And Misungwi Districts, Tanzania, Godfrey L. Chasama, Fred D. Chibwana, Aloyce S. Hepelwa, Jestina V. Katandukila

Tanzania Journal of Science

Increasing competition for feed resources and greenhouse gases pollution have been compelling beef production systems to operate at higher feed utilization. These challenges imply the need to breed cattle for Residual Feed Intake (RFI) to lower feeding costs and enteric methane production per output. To explore relevant indicator traits of RFI, this study investigated the association of RFI to Tanganyika Shorthorn Zebu (TSZ) cattle metrics from the Misungwi and Maswa Districts of Tanzania, where Tarime and Sukuma ecotypes are common. A correlation study involving the fattening of twenty-eight TSZ bulls was conducted at Tanzania Livestock Research Institute -Mabuki. From the …

Phytochemical Constituents Of Cissus Oliveri Growing In Pwani Region, Tanzania, Fadhili S. Estomini, Stephen I. Nnungu, Amelia S. Buriyo

Tanzania Journal of Science

Cissus oliveri (Engl.) Gilg ex Engl. is among the plant species of the family Vitaceae widely used in traditional medicine for management of different ailments. This study aimed at assessing the phytochemicals of C. oliveri parts in order to provide scientific validation for its use as a therapeutic agent. Qualitative analysis of water and ethanolic extracts was conducted by using standard methods and the results revealed that all the parts possess alkaloids, flavonoids, phenols and tannins. Similarly, glycosides and saponins were only present in leaf and root. Quantitative analysis performed by gravimetric and spectrophotometric methods showed that all parts contain …

A New Dietary Fiber Can Enhance Satiety And Reduce Postprandial Blood Glucose In Healthy Adults: A Randomized Cross-Over Trial, Simou Wu, Wen Jia, Huimin He, Jun Yin, Huilin Xu, Chengyuan He, Qinqiu Zhang, Yue Peng, Ruyue Cheng

Faculty, Staff and Student Publications

BACKGROUND: Dietary fiber plays a potential role in regulating energy intake and stabilizing postprandial blood glucose levels. Soluble dietary fiber has become an important entry point for nutritional research on the regulation of satiety.

METHODS: this was a double-blind, randomized cross-over trial enrolling 12 healthy subjects to compare the effects of RPG (R+PolyGly) dietary fiber products (bread, powder, and capsule) and pectin administered with a standard meal on satiety, blood glucose, and serum insulin level.

RESULTS: Adding 3.8% RPG dietary fiber to bread significantly increased the volume, water content, hardness, and chewiness of bread compared to 3.8% pectin bread and …

Relationships Between Dietary Intake And Alertness Among 12-Hour Shift Nurses, Charis Williams, Ross Bindler, Marian Wilson, Teresa Rangel

Central Division Nurse Clinical Inquiry Conference

No abstract provided.

Physical Decline Rates: Men Versus Women, Ray C. Fair

Cowles Foundation Discussion Papers

This paper uses world records by age in running, swimming, and rowing to estimate a biological frontier of decline rates for both men and women. Decline rates are assumed to be linear in percent terms up to a certain age and then quadratic after that, where the transition age is estimated. For both men and women decline rates are smallest for rowing, followed by swimming and then running.

Decline rates for women are roughly the same as those for men for the short swimming events. They are slightly larger for the longer swimming events and for the rowing events. They …

Recurrent Lower Urinary Tract Infections: More Than An Infection For Older Women, Sencer Gani̇dağli, Ercüment Öztürk, Zeynel Abi̇di̇n Öztürk

Turkish Journal of Medical Sciences

Background/aim: Older adults tend to have more urinary tract infections (UTIs). The frequency of recurrent lower urinary tract infections (rLUTIs) increases with age. rLUTIs are associated with long-term chronic effects on geriatric syndromes in older adults. We aimed to investigate possible risk factors that influence rLUTIs in older adults based on comprehensive geriatric assessment (CGA). Materials and methods: This cross-sectional study included 235 older adults admitted to Gaziantep University?s Geriatric Outpatient Clinic between June 1 and November 30, 2022. All patients underwent CGA. The Geriatric Depression Scale (GDS), the European Quality of Life-Five Dimension (EQ-5D) questionnaire, the Pittsburgh Sleep Quality …

Mapping The Dna Of Conspiracy Theories: Analyzing Key Nodes Across Digital Geographies, Carleigh J. Davis, Ryan Cheek, Kathryn C. Dolan, Rachel M. Schneider

English and Technical Communication Faculty Research & Creative Works

This project articulates a new methodology, Discursive Nodal Analysis (DNA) to explore and track the growth, spread, and interaction of conspiracy-oriented communities in digital spaces. By utilizing a combination of social network analysis (SNA), critical discourse analysis (CDA), and memetic rhetorical analysis (MRA), DNA empowers researchers to explore the unique rhetorical characteristics of online conspiracy theories that enable their evolution within digital environments while simultaneously tracking and analyzing their velocity and spread. Through an examination of discursive patterns, rhetorical strategies, and the mapping of communicative networks in digital communities, this methodology seeks to shed light on the dynamics of conspiracy …

Measuring Monetary And Non-Monetary Roi At Mmc Opex, Suneela Nayak, Natalia Johnson, Rebecca A. Brookes, Jill Shiroki

Operations Transformation

Operational Excellence (OpEx) is a data driven approach to department based continuous improvement, minimizing costs, increasing efficiencies, engaging staff in a shared quality agenda and assuming a proactive approach to maintaining facilities. The OpEx platform assists in strengthening efficiency and patient safety at Maine Medical Center (MMC) by demonstrating alignment of goals across the entire organization. A recent publication by BMC Health services “… found that the ROI concept in healthcare QI aligned with the concepts of value and benefit, both monetary and non-monetary.”2. Currently, OpEx does not have a system in place to track these values. We are looking …

Dietary Inflammatory Index Score And Its Association With Body Mass Index, Body Fat Percentage, Body Fat Mass, And Lipid Profile In Patients With Multiple Sclerosis, Seda Kaya, Zeynep Uzdi̇l, Ni̇ti̇n Shi̇vappa, James R. Hebert, Pinar Sökülmez Kaya, Murat Terzi̇

Turkish Journal of Medical Sciences

Background/aim: Multiple sclerosis (MS) may cause modifications in body composition, particularly for body fat associated with obesity and some biochemical parameters such as lipid profiles. We investigated whether there is a link between the inflammatory contents of diets and body composition and lipid profiles in patients with MS. Materials and methods: This was a cross-sectional study that included 85 MS patients. The study data of the patients were collected in the Neurology Clinic of Ondokuz Mayıs University?s Health Practice and Research Center. The data included demographic characteristics; anthropometric measurements such as body weight, height, body mass index, waist circumference, hip …

Evaluation Of Vitamin D Levels And Biochemical Markers In Infants Diagnosed With Laryngomalacia, Nagi̇han Bi̇lal, Ömer Faruk Çinar, Sevcan İpek, Muhammed Seyi̇thanoğlu, Adem Doğaner, Muhammed Gazi̇ Yildiz

Turkish Journal of Medical Sciences

Background/aim: The pathology of laryngomalacia is still not clear. The aim of this study was to investigate the relationship between vitamin D levels and laryngomalacia, and to evaluate vitamin D levels according to the classification of laryngomalacia. Materials and methods: This retrospective study was conducted in the Kahramanmaraş Sütçü İmam University Medicine Faculty?s Otorhinolaryngology Clinic between June 2014 and January 2021. Laryngomalacia was classified. Laboratory tests for all patients included calcium (Ca), phosphorus (P), parathormone (PTH), blood urea nitrogen (BUN), creatinine (Cre), alanine transaminase (ALT), and 25-hydroxy vitamin D (25-OH-D). Results: Evaluations were performed for 64 infants with laryngomalacia, including …

Dietary Habits, Meal Timing, And Meal Frequency In Kuwaiti Adults: Analysis Of The Kuwait National Nutrition Surveillance Data, Fatema Alkhulaifi, Suad Al-Hooti, Sameer Al-Zenki, Husam Alomirah, Charles Darkoh

Faculty, Staff and Student Publications

Dietary habits, including meal frequency, meal timing, and skipping meals, have been extensively studied due to their association with the development of noncommunicable diseases (NCDs). This study describes dietary habits, meal timing, frequency, skipping meals, and late-night eating in Kuwaiti adults. Kuwait National Nutrition Surveillance System data were utilized to reach the objectives of this study. The findings reveal that approximately 54% of the adults in Kuwait eat after 10 p.m., 29% skip breakfast, and 9.8% skip dinner. Furthermore, adults in Kuwait consume 4.4 meals per day on average. Women skip breakfast more often and have more extended night fasting …

Impacting T-Cell Fitness In Multiple Myeloma: Potential Roles For Selinexor And Xpo1 Inhibitors, Adam Binder, Christopher Walker, Tomer Mark, Muhamed Baljevic

Department of Medical Oncology Faculty Papers

Competent T-cells with sufficient levels of fitness combat cancer formation and progression. In multiple myeloma (MM), T-cell exhaustion is caused by several factors including tumor burden, constant immune activation due to chronic disease, age, nutritional status, and certain MM treatments such as alkylating agents and proteasome inhibitors. Many currently used therapies, including bispecific T-cell engagers, anti-CD38 antibodies, proteasome inhibitors, and CART-cells, directly or indirectly depend on the anti-cancer activity of T-cells. Reduced T-cell fitness not only diminishes immune defenses, increasing patient susceptibility to opportunistic infections, but can impact effectiveness MM therapy effectiveness, bringing into focus sequencing strategies that could modulate …

Lived Experiences Involving Self-Efficacy Among African American Women Receiving Cardiac Peer Support, Shurnett Arnella Barrett

Walden Dissertations and Doctoral Studies

Cardiovascular disease (CVD) is the leading cause of death among African American (AA) women in the United States. While there have been advances and more widespread use of peer-to-peer (P2P) support strategies to improve self-management skills among CVD patients, these approaches have not affected AA women, who continue to die from heart disease at significantly high rates. The purpose of this study was to examine real-life experiences of AA women with hypertensive heart disease who receive P2P support and the effect of that support on self-efficacy and cardiac health. The health belief model and social cognitive learning theory were the …

The Effect Of Natural Surfactants On The Development Of Postoperative Intraabdominal Adhesion, Ahmet Gökhan Güler, Ali̇ Erdal Karakaya, Ahmet Burak Doğan, Abdulkadi̇r Yasi̇r Bahar, Sadik Yurttutan

Turkish Journal of Medical Sciences

Background/aim: The development of postoperative adhesion after abdominal surgery is sometimes a severe problem. Our study investigates the effectiveness of exogenous surfactant application in preventing adhesion development in the experimental adhesion model. Materials and methods: This randomized-controlled interventional study was carried out in the animal laboratory of Kahramanmaraş Sütçü İmam University between March 1 and March 31, 2020. An experimental intra-abdominal adhesion model was established in 24 adult female rats by cecal abrasion. Rats were randomly divided into four groups. Groups I, II, and III were taken intraperitoneally as beractant, poractant, and calfactant applied groups, respectively. Group IV was the …

When Should A Premature Neonate (24?35 Weeks) Be Discharged? Five-Year Experience From A Single-Center Neonatal Intensive Care Unit In Türkiye, Ayşen Orman, Yalçin Çeli̇k, Semra Erdoğan

Turkish Journal of Medical Sciences

Background/aim: The survival rate among preterm infants has improved, and hospital stays have been prolonged, consistent with positive developments in perinatal and neonatal care. The aim of this study was to provide evidence-based information for healthcare professionals concerning the ideal time for discharge by evaluating the reasons for prolonged hospital stays. Materials and methods: Six hundred eighty-one premature babies born at 24?35 weeks at the Mersin University Medical Faculty Hospital between January 2016 and May 2020 and admitted to the neonatal intensive care unit were included in the study following a retrospective file examination. Date of birth (gestational age) and …

Evaluation Of Syringin?S Neuroprotective Effect In A Model Of Neonatal Hypoxic-Ischemic Brain Injury, Ezgi̇ Yangin Ergon, Asli Çeli̇k, Ayşe Gülden Di̇ni̇z Ünlü, Rüya Çolak, Senem Alkan Özdemi̇r, Şebnem Çalkavur, Osman Yilmaz

Turkish Journal of Medical Sciences

Background/aim: A significant cause of mortality and morbidity in the neonatal era is hypoxic-ischemic encephalopathy (HIE). This study examined the histopathological analysis and neuroprotective impact of syringin (SYR) in an experimental HIE rat model. Material and methods: On the 7th postnatal day, 24 Wistar albino rats were evaluated in 3 groups using the HIE model under gas anesthesia. In the experiment, Group A received 10 mg/kg SYR plus dimethyl sulfoxide (DMSO), Group B received DMSO only, and Group C served as a sham group. Immunohistochemical techniques were used to assess apoptotic cell measurement and proinflammatory cytokines (TNF-? and IL-1ß primary …