Digital Commons Network^™

Healthcare Providers’ Knowledge And Implementation Of Pneumococcal Vaccination Recommendations, Lara Blake, Pam White

MSN Research Projects

Streptococcal pneumoniae is a vaccine preventable disease but remains a leading cause of disease and death in the United States. In 2016, Streptococcal pneumoniae was responsible for 1.2 million deaths in over 195 countries. The illness is attributed to patients having invasive diseases, comorbid diseases, disability and death. The number of adults contracting Streptococcal pneumonia could be lowered dramatically with the use of proper vaccination, which is readily available. In 2022, the Center for Disease Control and the Advisory Committee on Immunization Practices (ACIP) release a new timing schedule and guidelines regarding the vaccination for pneumonia in the adult population. …

Eating Change: A Critical Autoethnography Of Community Gardening And Social Identity, Jessica Gerrior

Antioch University Dissertations & Theses

Community gardening efforts often carry a social purpose, such as building climate resilience, alleviating hunger, or promoting food justice. Meanwhile, the identities and motivations of community gardeners reflect both personal stories and broader social narratives. The involvement of universities in community gardening projects introduces an additional dimension of power and privilege that is underexplored in scholarly literature. This research uses critical autoethnography to explore the relationship of community gardening and social identity. Guided by Chang (2008) and Anderson and Glass-Coffin (2013), a systematic, reflexive process of meaning-making was used to compose three autoethnographic accounts. Each autoethnography draws on the author’s …

Deconstructing Orthorexia In An Age Of Healthism And Social Media, Maddison Paul

Antioch University Dissertations & Theses

Orthorexia, a pathological fixation with healthy eating, has recently emerged as a construct of interest in the field of clinical psychology. Despite its growing recognition, the origin of this construct remains unclear. This dissertation aims to contribute to the understanding of orthorexia by examining its emergence and contextual factors through a constructivist lens. The study found that the cultural, economic, and moralistic landscape of healthism and social medially have played a role in the development of orthorexia. The dominant clinical perspective of orthorexia was also deconstructed, revealing potential biases that may lead to pathologizing the experiences of those who demonstrate …

Development Of A Clinical Prediction Model For Diabetes In Chronic Pancreatitis: The Predict3c Study, Christie Jeon, Phil A Hart, Liang Li, Yunlong Yang, Eleanor Chang, Melena D Bellin, William E Fisher, Evan L Fogel, Christopher E Forsmark, Walter G Park, Stephen K Van Den Eeden, Santhi Swaroop Vege, Jose Serrano, David C Whitcomb, Dana K Andersen, Darwin L Conwell, Dhiraj Yadav, Mark O Goodarzi

Faculty, Staff and Student Publications

Objective: Diabetes that arises from chronic pancreatitis (CP) is associated with increased morbidity and mortality. Methods to predict which patients with CP are at greatest risk for diabetes are urgently needed. We aimed to examine independent risk factors for diabetes in a large cohort of patients with CP.

Research design and methods: This cross-sectional study comprised 645 individuals with CP enrolled in the PROCEED study, of whom 276 had diabetes. We conducted univariable and multivariable regression analyses of potential risk factors for diabetes. Model performance was assessed by area under the receiver operating characteristic curve (AUROC) analysis, and accuracy was …

Dietary Behaviours During Covid-19 Among Households At Risk For Food Insecurity, Maha Almohamad, Allison Marshall, Jayna Markand Dave, Ru-Jye Chuang, Christine Markham, Shreela Sharma

Faculty, Staff and Student Publications

The objective of the present study was to examine associations between variables of COVID-19-related concerns and changes in fruit and vegetable (FV) consumption among a sample of participants from the Brighter Bites program at risk for food insecurity. Cross-sectional data were collected during April-June 2020 using a rapid-response survey to understand social needs, COVID-19-related concerns and diet-related behaviours among families with children participating in Brighter Bites (

Researcher Views On Changes In Personality, Mood, And Behavior In Next-Generation Deep Brain Stimulation, Peter Zuk, Clarissa E Sanchez, Kristin Kostick-Quenet, Katrina A Muñoz, Lavina Kalwani, Richa Lavingia, Laura Torgerson, Demetrio Sierra-Mercado, Jill O Robinson, Stacey Pereira, Simon Outram, Barbara A Koenig, Amy L Mcguire, Gabriel Lázaro-Muñoz

Center for Medical Ethics and Health Policy Staff Publications

The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (

Advanced Photon Counting Ct Imaging Pipeline For Cardiac Phenotyping Of Apolipoprotein E Mouse Models, Alex J Allphin, Ali Mahzarnia, Darin P Clark, Yi Qi, Zay Y Han, Prajwal Bhandari, Ketan B Ghaghada, Alexandra Badea, Cristian T Badea

Faculty, Staff and Students Publications

Background: Cardiovascular disease (CVD) is associated with the apolipoprotein E (APOE) gene and lipid metabolism. This study aimed to develop an imaging-based pipeline to comprehensively assess cardiac structure and function in mouse models expressing different APOE genotypes using photon-counting computed tomography (PCCT).

Methods: 123 mice grouped based on APOE genotype (APOE2, APOE3, APOE4, APOE knockout (KO)), gender, human NOS2 factor, and diet (control or high fat) were used in this study. The pipeline included PCCT imaging on a custom-built system with contrast-enhanced in vivo imaging and intrinsic cardiac gating, spectral and temporal iterative reconstruction, spectral decomposition, and deep learning cardiac …

Safety Procedures To Work With West Nile Virus In Biosafety Level 3 Facilities, Freedom M Green, Shannon E Ronca

Faculty, Staff and Students Publications

West Nile virus (WNV) can cause severe and sometimes fatal disease, but we do not have treatments or therapeutics to manage these outcomes. Since its introduction to the USA in 1999, WNV has been handled in a biosafety level 3 laboratory to decrease risk to researchers, requiring strict safety protocols and important considerations with planning experiments. Recent changes in US guidelines suggest that WNV can be handled at a lower biosafety level due to its endemicity in the USA and generally minor symptoms, but some research still requires the use of the agent at biosafety level 3. This chapter will …

Cerebral Microdialysis And Glucopenia In Traumatic Brain Injury: A Review, Himanshu Sharma, John P Mcginnis, Katherine E Kabotyanski, Shankar P Gopinath, Jerry C Goodman, Claudia Robertson, Jovany Cruz Navarro

Faculty, Staff and Students Publications

Traditionally, intracranial pressure (ICP) and partial brain tissue oxygenation (PbtO2) have been the primary invasive intracranial measurements used to guide management in patients with severe traumatic brain injury (TBI). After injury however, the brain develops an increased metabolic demand which may require an increment in the oxidative metabolism of glucose. Simultaneously, metabolic, and electrical dysfunction can lead to an inability to meet these demands, even in the absence of ischemia or increased intracranial pressure. Cerebral microdialysis provides the ability to accurately measure local concentrations of various solutes including lactate, pyruvate, glycerol and glucose. Experimental and clinical data demonstrate that such …

Moab Local Food Guide 2023, Roslynn Mccann, Shiree Duncan

All Current Publications

Thank you for picking up this Moab Utah Local Food Guide, last updated in May 2023. Those growing and producing food within a 100 mile radius from Moab have been included in this guide to help YOU make locally sourced purchasing decisions!

Addressing Training Gaps: A Competency-Based, Telehealth Training Initiative For Community Health Workers, Laura Porterfield, Victoria Warren, Vanessa Schick, Shannon Gulliot-Wright, Jeff R Temple, Elizabeth M Vaughan

Faculty, Staff and Student Publications

BACKGROUND: To overcome vast variations in Community Health Worker (CHW) training, investigators for the CHW Core Consensus Project (CCCP) derived three types of CHW (Category 1, 2, 3) and established competencies for each category. However, studies are needed that implement these competencies in real-world settings.

OBJECTIVE: Using the six competency domains of the CCCP as a theoretical backbone, we developed and evaluated a training for

METHODS: We developed five telehealth-based, bilingual (Spanish/English) training sessions and implemented them among

RESULTS: All (18/18) CHWs achieved at least 70% on the posttest (mean: 93.7%; range 73.3-100%). Training attendance was 98.9%. Using a six-point …

Catching Babies: Helping Students Understand Reproductive Justice Through Black Maternal Health, Jillian A. Tullis

Communication: Faculty Scholarship

No abstract provided.

Mass Spectrometry-Based Proteomic Analysis To Characterise Barley Breeding Lines, Mahya Bahmani

Theses: Doctorates and Masters

Barley is a key ingredient in the malting and brewing industry, and it is the fourth most important crop being cultivated worldwide. The protein content of the barley grain is one of the main components determining the quality and nutritive value of the food and beverages prepared from barley. Mass spectrometry-based proteomic analysis is a valuable tool that can guide and inform plant breeding strategies and crop improvement programs. Understanding the proteome changes in barley grain under different growing locations, the impact of different environmental conditions and its relationship with malting characteristics have the potential to inform breeding programs to …

Associations Between Oyster Consumption And Iron, Zinc, And Cadmium Concentrations In Ghanaian Women, Alyssa Abreu

Open Access Dissertations

Background: Oysters are an excellent source of iron and zinc but may be contaminated by heavy metals such as cadmium. The micronutrient and metal content of smoked, dried oysters as well as the impact of oyster consumption on iron, zinc, and cadmium concentrations in Ghana is unknown.

Objectives: Our objectives were to 1) determine the micronutrient and metal content and health risk of dried, smoked oysters, 2) determine the associations between dietary iron intake with hemoglobin or ferritin concentrations and anemia, 3) determine the associations between oyster consumption and iron, zinc and cadmium concentrations in Ghanaian women living near the …

Cranberry Vine And Its Effects On The Periparturient Ovine And Her Offspring, Delaney Smith

Open Access Dissertations

Gastrointestinal nematodes (GIN) are a major health concern globally, particularly for small ruminant producers. The most deadly of these GIN is an anemia-inducing parasite called Haemonchus contortus. Infections of H. contortus are most severe during what's known as the periparturient period (PPP), which is the last 6 weeks of gestation and first 8 weeks of lactation in maternal animals. Widespread genetic resistance of H. contortus to the traditionally used chemical dewormers have led producers and researchers alike to turn to the plant kingdom for answers. Plant based compounds have been used as bioactive compounds for centuries to cure a …

Elucidating The Mechanisms Of Stress Tolerance In Reef-Building Coral Holobionts, Emma Strand

Open Access Dissertations

Coral reefs worldwide are threatened by climate change effects like increasing ocean warming and ocean acidification. These increased pressures cause a dysbiosis between the coral host, algal endosymbionts, and associated coral microbiome that results in the coral host expelling algal endosymbionts, leaving the coral host with a stark white ‘bleached’ appearance. Without their endosymbionts, coral hosts are forced to sustain themselves energetically with heterotrophy instead of relying on the autotrophic carbon and energy sources that once came from the algal endosymbionts. When this response, termed ‘coral bleaching’, happens reef-wide during an extreme wave of increased ocean temperatures, this is called …

A Group Respite Intervention For Family Caregivers Of Children Living With Special Needs, Christine Mcgrane

Open Access Dissertations

Family caregiver stress is a growing healthcare concern as more and more families are providing a large portion of care at home. As a family caregiver, parents of children living with special needs are taking on this role as a lifelong journey with their child. Due to the provision of continuous caregiving, these parents are at higher risk for exhaustion, stress, and social isolation, and the challenges can impact both the child and family’s physical and emotional well-being. The demands of caregiving can impact their physical, mental, social, and financial health. As a society, the importance of caring for the …

Arts 3403 Printmaking Introduction, Acadia Kandora

All Syllabi

No abstract provided.

The Effect Of Acceptance And Commitment Therapy On Value Consistency During A Weight Loss Program, Leah Dorfman

Open Access Dissertations

In the last decade, the prevalence of obesity has increased significantly in populations worldwide. It is well established that overweight and obesity are associated with a host of deleterious health consequences. Standard Behavioral Therapy (SBT) for weight loss has been demonstrated to yield only modest outcomes with poor long-term maintenance. Therefore, efforts must be made to improve upon what is currently considered to be best practices in weight loss interventions, especially with a goal of improving retention and long-term maintenance. Acceptance and Commitment Therapy (ACT) is a behavioral and cognitive intervention that implements both acceptance and mindfulness processes, and commitment …

Biochemical And Genetic Mechanisms Underpinning Escherichia Coli Cell Cycle And Growth Transitions, Josiah Morrison

Open Access Dissertations

Bacterial cell division and the decision to divide is a process that requires a wide variety of factors. In bacterial cells, such as the widely studied Escherichia coli, a large protein complex, termed the Z-ring, assembles at midcell to enable division. The Z-ring is subject to many regulators which govern the spatiotemporal positioning of the ring. The Z-ring is made up of the eukaryotic tubulin homolog FtsZ, which polymerizes to recruit division proteins to the midcell. FtsZ polymers are tethered to the cytoplasmic membrane by the actin homolog FtsA. Together, FtsZ and FtsA act as the first step in …

Adapting A Mobile App To Support Patients With Anorexia Nervosa Following Post-Acute Care: Perspectives From Eating Disorder Treatment Center Stakeholders, Anneliese Haas, Agatha A Laboe, Claire G Mcginnis, Marie-Laure Firebaugh, Jillian Shah, Anna M Bardone-Cone, Kathleen M Pike, C Barr Taylor, Denise E Wilfley, Ellen E Fitzsimmons-Craft

2020-Current year OA Pubs

INTRODUCTION: Anorexia nervosa (AN) is a harmful, life-threatening illness. Patients with severe AN often receive acute treatment but, upon discharge, experience high relapse rates. Evidence-based, outpatient treatment following acute care is critical to preventing relapse; however, numerous barriers (e.g., location, financial limitations, low availability of providers) preclude individuals from accessing treatment. mHealth technologies may help to address these barriers, but research on such digital approaches for those with AN is limited. Further, such technologies should be developed with all relevant stakeholder input considered from the outset. As such, the present study aimed to garner feedback from eating disorder (ED) treatment …

Women's Empowerment And Child Nutrition In A Context Of Shifting Livelihoods In Eastern Oromia, Ethiopia, Karah Mechlowitz, Mark J Manary, Et Al.

2020-Current year OA Pubs

Agriculture, and particularly livestock and animal source foods, has been closely linked to improvements in human nutrition. Production, income, and women's empowerment improve household food security and child nutritional outcomes in interacting ways. Khat production in Eastern Ethiopia is changing the economic and livelihood landscape for communities that have traditionally relied upon small-scale mixed agriculture and livestock production. How this shifting livelihood landscape and the empowerment of women in these communities are affecting nutritional outcomes has not been investigated. Using cross-sectional data collected during formative research for the Campylobacter Genomics and Environmental Enteric Dysfunction (CAGED) project, we developed models to …

Vancomycin-Induced Gut Microbial Dysbiosis Alters Enteric Neuron-Macrophage Interactions During A Critical Period Of Postnatal Development, Ellen Merrick Schill, Elisabeth L Joyce, Alexandria N Floyd, Sreeram Udayan, Brigida Rusconi, Shreya Gaddipati, Bibiana E Barrios, Vini John, Mitchell E Kaye, Devesha H Kulkarni, Jocelyn T Pauta, Keely G Mcdonald, Rodney D Newberry

2020-Current year OA Pubs

Vancomycin is a broad-spectrum antibiotic widely used in cases of suspected sepsis in premature neonates. While appropriate and potentially lifesaving in this setting, early-life antibiotic exposure alters the developing microbiome and is associated with an increased risk of deadly complications, including late-onset sepsis (LOS) and necrotizing enterocolitis (NEC). Recent studies show that neonatal vancomycin treatment disrupts postnatal enteric nervous system (ENS) development in mouse pups, which is in part dependent upon neuroimmune interactions. This suggests that early-life antibiotic exposure could disrupt these interactions in the neonatal gut. Notably, a subset of tissue-resident intestinal macrophages, muscularis macrophages, has been identified as …

Microbiome-Targeting Therapies In The Neonatal Intensive Care Unit: Safety And Efficacy, Anna Deveaux, Jian Ryou, Gautam Dantas, Barbara B Warner, Phillip I Tarr

2020-Current year OA Pubs

Microbiome-targeting therapies have received great attention as approaches to prevent disease in infants born preterm, but their safety and efficacy remain uncertain. Here we summarize the existing literature, focusing on recent meta-analyses and systematic reviews that evaluate the performance of probiotics, prebiotics, and/or synbiotics in clinical trials and studies, emphasizing interventions for which the primary or secondary outcomes were prevention of necrotizing enterocolitis, late-onset sepsis, feeding intolerance, and/or reduction in hospitalization length or all-cause mortality. Current evidence suggests that probiotics and prebiotics are largely safe but conclusions regarding their effectiveness in the neonatal intensive care unit have been mixed. To …

Covid-19 Return To Sport: Collegiate Baseball Injury Prevalence Analysis, Troy B. Puga, Joshua Schafer, Grace Thiel, Laura Ramaker, Tejas Patel, Kevin Treffer

Faculty and Staff Publications

In the spring of 2020, the COVID-19 pandemic rapidly brought college baseball to a halt. Most college baseball players saw disruption of their training and development due to interruptions of their seasons. With these interruptions, it is necessary to examine the effects of the COVID-19 pandemic on collegiate baseball injury epidemiology. Data from a small-school Midwest collegiate conference was tallied for the number of collegiate conference injuries per year, and for the injuries per anatomic region. An unpaired t-test was conducted upon the overall conference mean injuries per year and on each anatomic region for the mean injuries per region …

On Fires, Floods, And Federalism, Andrew Hammond

Articles by Maurer Faculty

In the United States, law condemns poor people to their fates in states. Where Americans live continues to dictate whether they can access cash, food, and medical assistance. What’s more, immigrants, territorial residents, and tribal members encounter deteriorated corners of the American welfare state. Nonetheless, despite repeated retrenchment efforts, this patchwork of programs has proven remarkably resilient. Yet, the ability of the United States to meet its people’s most basic needs now faces an unprecedented challenge: climate change. As extreme weather events like wildfires and hurricanes become more frequent and more intense, these climate-fueled disasters will displace and impoverish more …

Evaluation Of The Dynamic Indicators Of Basic Early Literacy Skills (Dibels 8th Edition) Measures For Use With The Energy Express Summer Literacy Program, Maria Boki

Graduate Theses, Dissertations, and Problem Reports (ETD)

The present study examines the suitability of the DIBELS 8^th edition assessment for use within the scope and context of the Energy Express summer literacy program. The 6-week summer program helps children in grades K-5 from rural and low-income West Virginia communities improve or maintain their reading levels over the summer months. Standard, grade-appropriate DIBELS 8^th subtests were administered to 1,065 participants at the beginning and end of Summer 2022. The resulting pre- and post-scores were cross-referenced with demographic data and attendance rates from 20 counties and 35 sites in West Virginia. They were then analyzed for correlations …

Survival Of Listeria Monocytogenes On Organic Honeycrisp And Fuji Apples During Storage At 5, 12 And 22.5◦C, Connor S. Freed

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study aimed to evaluate and model the survival of Listeria monocytogenes on organic HoneyCrisp (HC) and Fuji (FJ) apples during storage at various temperatures. Fresh organic HC and FJ apples (without wax coating) obtained from a local wholesale market were inoculated with a 2-strain mix of L. monocytogenes followed by storage at 5.0 (22.9% RH), 12.0 (37.0% RH), and 22.5oC (50.4% RH) for 60, 35, 7 days, respectively, and periodically (day-0 to 60) analyzing microbial populations. Surviving L. monocytogenes were spread-plated on Modified-Oxford agar after 10 or 100-fold serial dilution. Data were analyzed using the mixed-model procedure of SAS …

Clinical And Economic Burden Of Inflammatory Chronic Conditions Among Adults In The United States: Evidence From Three Nationally Representative Surveys, Mohammad Ikram

Graduate Theses, Dissertations, and Problem Reports (ETD)

A significant proportion of adults in the United States (US) suffer from various inflammatory chronic conditions (ICCs). They include a wide range of diseases such as diabetes, rheumatoid arthritis, asthma, and chronic obstructive pulmonary diseases. ICCs are not curable, and their management typically involves medications such as NSAIDs and corticosteroids. Recently, a whole health approach that places patients’ well-being at the center is increasingly being used for better management of ICCs. The whole health approach uses an integrated approach that includes multimodal management with complementary and alternative medicines (CAM) and prescription drugs. However, the use of CAM and prescription drugs …

Lipid Binding Properties Of Huntingtin As A Novel Therapeutic Target, Chathuranga Siriwardhana

Graduate Theses, Dissertations, and Problem Reports (ETD)

As protein aggregation is the defining hallmark of all amyloid diseases, a common therapeutic strategy is to develop molecules that inhibit aggregation. However, this approach has yielded limited success. Many amyloid proteins directly interact with lipid membranes. These interactions promote distinct aggregation pathways and often result in membrane damage leading to toxicity. As a result, directly targeting the ability of amyloids to bind lipid membranes represents a novel therapeutic strategy. As a proof of principle, the interaction between lipid membranes and mutant huntingtin protein (htt) aggregates was used to test this strategy. Mutant htt containing an expanded polygulatmine (polyQ) domain …