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2023

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Is The Relationship Between Adverse Childhood Experiences And Adult Belief In Paranormality Moderated By Locus Of Control?, Michelle Alessia Cardone M.S., M.A. Jan 2023

Is The Relationship Between Adverse Childhood Experiences And Adult Belief In Paranormality Moderated By Locus Of Control?, Michelle Alessia Cardone M.S., M.A.

Selected Full Text Dissertations, 2011-

Research has established a relationship between adverse childhood experiences (ACEs) and belief in paranormal phenomena (Lawrence et al., 1994). In the present study, I sought to replicate this finding in more detail by examining seven dimensions of paranormality. Further, the current study investigated whether locus of control moderated the relationship between ACEs and paranormal belief. I hypothesized that ACEs positively correlated with paranormal belief. Further, I hypothesized that the relationship between ACEs and paranormal belief would be moderated by locus of control, such that, the stronger the internal locus of control, the weaker the relationship between ACEs and paranormal belief. …

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Heaven Education: Utilizing Mixed Methods To Analyze Why Gifted Education Is Culturally Relevant For Chinese Americans, Julie M. Milner Jan 2023

Heaven Education: Utilizing Mixed Methods To Analyze Why Gifted Education Is Culturally Relevant For Chinese Americans, Julie M. Milner

Selected Full Text Dissertations, 2011-

This mixed methods study examined why gifted education is culturally relevant to Chinese Americans and why parents desire gifted education for their children. At a time when accelerated learning is at odds with equity ideals, parents from the communities comprising the Asian umbrella have mobilized to fight to keep these academic opportunities for their children. These parents have been labeled as ‘white adjacent’ in order to shut them down as ‘racists’ when they speak out. The large number of Asian students in accelerated education has led to the accusation of them being ‘resource hoarders’. Even gifted education scholars have used …

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Faculty Perceptions And Beliefs About Utilizing Social Media As A Teaching Tool In Higher Education: A Q Methodology Study, April Robinson Jan 2023

Faculty Perceptions And Beliefs About Utilizing Social Media As A Teaching Tool In Higher Education: A Q Methodology Study, April Robinson

Selected Full Text Dissertations, 2011-

The purpose of this study was to examine college faculty’s perceptions, beliefs, and attitudes concerning the use of social media as a teaching and learning tool, and to determine possible factors that may influence their perceptions, beliefs, and attitudes about social media use in the classroom. For this purpose, Q Methodology which is a mixed-methods approach was used to study the subjectivity of the participant’s perceptions and beliefs objectively. Q methodology systematically can reveal the shared perceptions and beliefs of college faculty. Data were analyzed from 19 teaching faculty in Long Island, New York. This study identified and examined the …

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Spilling The Tea, Memoir Of A Future's Past: A Scholarly Personal Narrative, Dominique Jerome Hector Jan 2023

Spilling The Tea, Memoir Of A Future's Past: A Scholarly Personal Narrative, Dominique Jerome Hector

All ETDs from UAB

Lesbian, Gay, Bisexual, Transgender, and Questioning (LGBTQ) individuals and topics have been at the precipice of media coverage and policy decisions for decades. With the passage of same sex marriage by the Supreme Court in 2015, this ushered in a new era of unearthing narratives that are unique to LGBTQ+ identities. Although this is a huge advancement for this population here within the United States, scholars have posited how these identities intersecting with other social constructs such as race, gender, socioeconomic status, and social justice have reimaged how LGBTQ+ identities are viewed and treated in the country. Although there is …

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Alternating Current Electrospinning And Characterization Of Nanofibrous Fish Skin Gelatin As An Innovative Biomaterial Platform, Amanda Kennell Jan 2023

Alternating Current Electrospinning And Characterization Of Nanofibrous Fish Skin Gelatin As An Innovative Biomaterial Platform, Amanda Kennell

All ETDs from UAB

A biomaterial for tissue repair is globally sought after, as transplant surgeries and general wound healing have a strong need for a manufactured scaffold that mimics the natural body’s tissue in morphology, composition, and properties. This research presents a nanofibrous (NF) fish skin gelatin-based (FSG) substrate fabricated through an uncommon high-yield method of Alternating Current electrospinning that mimics that can mimic the natural body’s extracellular matrix (ECM). An ECM is the first step in tissue repair. Fabrication through electrospinning gave the NF FSG substrate an identical mimic of the natural body’s extracellular matrix morphology with nanofiber diameter on the order …

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Investigating Scientific Self-Concept In The General Chemistry Laboratory While Performing Course-Based Undergraduate Research Throughout A Pandemic, Josh Forakis Jan 2023

Investigating Scientific Self-Concept In The General Chemistry Laboratory While Performing Course-Based Undergraduate Research Throughout A Pandemic, Josh Forakis

All ETDs from UAB

Climate change, waste management crises, and global pandemics emphasize the need for a thriving science, technology, engineering, and mathematics (STEM) workforce, and one of the jobs of STEM educators is to provide meaningful educational experiences that engage STEM students in scientific practices, broaden their worldview, and prepare them for a future career in the scientific field. Undergraduate research experiences have been shown to benefit STEM students, but few students can participate, especially at early stages in their undergraduate studies. To broaden participation in undergraduate research, an honors general chemistry laboratory course was converted into a course-based undergraduate research experience (CURE) …

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An Examination Of Clinical Pain Severity, Sleep Quality, And Neighborhood Disadvantage In A Racially/Ethically Diverse Sample Of Adults With Symptomatic Knee Osteoarthritis, Cesar Emmanuel Gonzalez Jan 2023

An Examination Of Clinical Pain Severity, Sleep Quality, And Neighborhood Disadvantage In A Racially/Ethically Diverse Sample Of Adults With Symptomatic Knee Osteoarthritis, Cesar Emmanuel Gonzalez

All ETDs from UAB

Knee osteoarthritis (OA) is often accompanied by insomnia symptoms, character-ized by difficulty falling asleep, maintaining sleep, or both. Among individuals with knee OA, up to 31% report significant difficulty falling asleep, 81% have difficulties staying asleep, and up to 77% report any sleep problem. However, the sleep and pain relationship has also rarely been evaluated using objective and subjective sleep measures. Thus, this study attempted to characterize objective and subjective sleep variables in a diverse sam-ple of individuals with symptomatic knee OA. Further, the impact of objective and sub-jective sleep quality on clinical pain severity, movement-evoked pain, and physical func-tion …

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Inkjet-Printed Reseroir Computing Network For In Situ Sensor Predictions, Steven D. Gardner Jan 2023

Inkjet-Printed Reseroir Computing Network For In Situ Sensor Predictions, Steven D. Gardner

All ETDs from UAB

The technological achievements made with silicon-based transistors have led to nearly all the computing seen today, complete with benefits such as maximized operating speeds, parallel/tensor processing, minimized power overhead, etc. The silicon electronics industry is foundational to scientific progression with its profound impact on modeling, simulations, and fast/reliable computing. However, silicon-based transistors have evolved to meet their physical limitations and have saturated fields of innovation. New fields in computing outside of silicon-based methods have emerged as exotic materials enter the research domain. The suite of super-performing materials like Graphene, Carbon Nanotubes, and Molybdenum Disulfide have chaotic, non-linear behaviors that make …

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Secure And Multimodal Personal Safety In Smart Cities With Applications In Interactions And Privacy Preservation For Pedestrians, Raiful Hasan Jan 2023

Secure And Multimodal Personal Safety In Smart Cities With Applications In Interactions And Privacy Preservation For Pedestrians, Raiful Hasan

All ETDs from UAB

The personal safety of pedestrians has increasingly been recognized as a global concern, with a multitude of contributing elements. These include distractions such as smart and wearable device usage, the absence of human-centric systems, infrastructure inadequacies, and traffic regulation. Individuals are increasingly experiencing physical harm as a consequence of reduced attention to their immediate environment, thereby compromising their personal safety. This phenomenon is becoming more prevalent in this fast-paced, technology-driven world, especially among the young. The proliferation of digital devices, such as smartphones and wearable technology, has led to a significant shift in people’s focus from their physical surroundings to …

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Macrophage Ipla2ss-Derived Lipid Signaling Contributes To Type 1 Diabetes Development, Abdulaziz Saad Almutairi Jan 2023

Macrophage Ipla2ss-Derived Lipid Signaling Contributes To Type 1 Diabetes Development, Abdulaziz Saad Almutairi

All ETDs from UAB

Type 1 Diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-secreting pancreatic β-cells that leads to hyperglycemia; however, the mechanism of β-cells destruction remains elusive. Ca2+-independent phospholipase A2β (iPLA2β), which hydrolyzes membrane phospholipids at the sn-2 position and releases bioactive lipids, modulates polarization of macrophages (M ). Data from our lab suggests that selective iPLA2β-derived lipid signals (iDLs) (i.e., PGs, HETEs, DHETs, LTB4) produced by M from spontaneous-T1D prone nonobese diabetic mice (NOD) are high during the pre-diabetic phase. However, the impact of macrophage-derived iDLs in T1D remains unclear. Therefore, we generated a NOD mouse model with …

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Impact Of Streptococcus Parasanguinis-Generated Reactive Nitrogen Species On Pseudomonas Aeruginosa Virulence And The Host Response, Joshua J. Baty Jan 2023

Impact Of Streptococcus Parasanguinis-Generated Reactive Nitrogen Species On Pseudomonas Aeruginosa Virulence And The Host Response, Joshua J. Baty

All ETDs from UAB

Streptococcus parasanguinis is an oral commensal bacterium that produces hydrogen peroxide. Hydrogen peroxide can react with endogenous molecules such as nitrite to form reactive nitrogen intermediates (RNI). These S. parasanguinis-mediated RNI have been shown to inhibit oral pathogens such as Streptococcus mutans, Enterococcus faecalis, and Aggregatibacter actinomycetemcomitans. As such, S. parasanguinis plays a protective role in the oral microbial ecosystem by antagonizing and preventing colonization by oral pathogens. In addition to being an important organism for the health of the oral cavity, S. parasanguinis has also been associated with improved outcomes for people with cystic fibrosis. There are two explanations …

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Exploring The Regulatory Mechanisms Of Ire1 Signaling In Biotic And Abiotic Stress Responses In Arabidopsis, Taiaba Afrin Jan 2023

Exploring The Regulatory Mechanisms Of Ire1 Signaling In Biotic And Abiotic Stress Responses In Arabidopsis, Taiaba Afrin

All ETDs from UAB

Given their immobility, plants have various survival strategies, including the critical ability to recognize and respond to stressors. Exposure to different environmental and intracellular signals triggers significant modifications in stress response regulators' expression. These changes often occur in the endoplasmic reticulum (ER), where a rise in protein synthesis can overwhelm the system, accumulating misfolded proteins and activating a mechanism known as the unfolded protein response (UPR). UPR is a complex regulatory network with three primary branches in eukaryotic systems. The IRE1-mediated pathway is the most conserved among UPR signaling branches. In Arabidopsis, IRE1 splices bZIP60 mRNA and produces a functional …

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Effects Of Mindfulness-Based Intervention On Mental Health Outcomes In Youth Who Are Underserved, Melanie Grace Albright Jan 2023

Effects Of Mindfulness-Based Intervention On Mental Health Outcomes In Youth Who Are Underserved, Melanie Grace Albright

All ETDs from UAB

olescence, a period of rapid brain maturation and development coincides with the development of mental health disorders. Many teens in the United States with diagnosable mental health conditions lack mental health treatment due to limited access and provider availability, particularly affecting adolescents who are underserved. School-based interventions, including those centered around mindfulness-based stress reduction (MBSR) have shown promise in their effectiveness among adolescents. This study examines the impact of an in-school MBSR-based program, MindUP, on mental health outcomes, including depressive symptomology, anxiety symptomology, and perceived stress, in adolescents who are underserved. Additionally, focus group discussions were conducted with students participating …

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The Role Of Runx2 And Sp7 In Ameloblast Differentiation And Postnasal Enamel Synthesis, Reem Alhefdhi Jan 2023

The Role Of Runx2 And Sp7 In Ameloblast Differentiation And Postnasal Enamel Synthesis, Reem Alhefdhi

All ETDs from UAB

In mammals, the mineralized tissues include bone, dentin, enamel, and cementum. Runx2 and its downstream target Sp7 are essential transcription factors for the osteoblast differentiation and formation of bone tissue. However, transcription factors that regulate ameloblast differentiation and enamel secretion are less understood. To uncover the role of Runx2 and Sp7 in ameloblasts differentiation and enamel synthesis, we established a colony of Runx2 and Sp7 floxed mice. Both genes were deleted specifically in ameloblasts using K14-Cre transgenic mice. The successful deletion of Runx2 and Sp7 genes in the epithelium, including ameloblasts, was confirmed using Td-Tomato and GFP reporter, respectively. Histological …

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Increasing Patient Safety By Reducing Falls Among In-Hospital Community-Dwelling Patients 65 Years Old Or Older By Using A Shift Change Fall Safety Checklist, Janice Isaac Brooks Jan 2023

Increasing Patient Safety By Reducing Falls Among In-Hospital Community-Dwelling Patients 65 Years Old Or Older By Using A Shift Change Fall Safety Checklist, Janice Isaac Brooks

All ETDs from UAB

This manuscript is designed to promote and improve healthcare safety, quality, efficiency, and lower medical costs for hospitals and patients. Falls, fall injuries, and their devastating consequences are rising, yet falls are preventable even among senior patients. Search Engines and Key Terms SciWheel was used to save the literature and eliminate duplications. Key terms were used in the Boolean strings: elderly fall prevention, senior fall safety, in-hospital fall prevention, falls in the aging, and fall prevention tools. The CINAHL Plus yielded 58. PubMed search yielded 121. And Google Scholar yielded 32. The total of all three searches was 211. Thirteen …

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Embracing Green Chile: An Exploratory Factor Analysis Of Community Cultural Wealth, Lynda Duran Jan 2023

Embracing Green Chile: An Exploratory Factor Analysis Of Community Cultural Wealth, Lynda Duran

Electronic Theses and Dissertations

Higher education trends marginalize Students of Color by promoting assimilation into a dominant culture. Faculty and practitioners in higher education deepen cultural dissociation by dismissing the cultural knowledge that many Students of Color hold from family and community. Following in the footsteps of settler colonialism, these practices uphold a deficit framing of Students of Color as inferior to their white peers. This dissertation blends the power of the Community Cultural Wealth model (Yosso, 2005) and QuantCrit (García et al, 2018; Gillborn et al., 2018) to define a Green Chile Epistemology that weaves cultural capital into the higher education experience. In …

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Transmission Competence Of B. Burgdorferi Infected Ixodes Ticks And Development Of An Ospc-Based Lyme Disease Vaccine, Samanta Kamalika Jan 2023

Transmission Competence Of B. Burgdorferi Infected Ixodes Ticks And Development Of An Ospc-Based Lyme Disease Vaccine, Samanta Kamalika

Theses and Dissertations (ETD)

Introduction. Lyme disease, otherwise called Lyme borreliosis, is a vector-borne infectious disease caused by the spirochete Borrelia burgdorferi (Bb). Studying the increase in overall Lyme disease incidence requires understanding the role of the vector Ixodes scapularis (I. scapularis) as the agent that carries the spirochete which is important to limit the occurrence of Lyme disease. Once we understand the vector-pathogen response, it also becomes important to determine the remedies for Lyme disease. Lyme disease can be treated with antibiotics if detected early, but the major obstacle lies in the early detection process. Therefore, it is important to investigate alternative preventive …

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Novel Role For St6gal1 Sialyltransferase As A Tumor Driver In Pancreatic Ductal Adenocarcinoma, Nikita Umakant Bhalerao Jan 2023

Novel Role For St6gal1 Sialyltransferase As A Tumor Driver In Pancreatic Ductal Adenocarcinoma, Nikita Umakant Bhalerao

All ETDs from UAB

ST6Gal1 sialyltransferase adds negatively charged sialic acid in an α2,6 linkage to N-glycans on glycoproteins bound for the cell surface/secretion thus altering receptor structure, function and downstream signaling pathways. ST6Gal1 is upregulated in multiple cancers, including pancreatic, and imparts cancer stem cell-like phenotype. Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with a survival rate of ~10%. Acinar to ductal metaplasia (ADM), the tumor initiation stage of PDAC, occurs in response to insults like pancreatitis, when acinar cells dedifferentiate and form ductal-like cells with stem and ductal gene upregulation. These cells, on acquiring mutations such as in KRAS gene, can …

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Temporal Trends In Tularemia Incidence In The United States From 2010 To 2020. Are Age And Sex Associated With These Changing Trends?, Carla V. Brooks Jan 2023

Temporal Trends In Tularemia Incidence In The United States From 2010 To 2020. Are Age And Sex Associated With These Changing Trends?, Carla V. Brooks

All ETDs from UAB

Background: Tularemia or Rabbit Fever was discovered in 1911 in a plague-like outbreak among rodents in Tulare County, California. Tularemia in the US has expanded from rural to more metropolitan areas, which may be potentially correlated with the escalating exposure of humans to animal vectors. There has not been a recent study evaluating trends in Tularemia, especially one that has evaluated if the trends in Tularemia over time differ by demographic characteristics. Methods: This is an ecological study to evaluate the temporal trends and if trends Tularemia incidence over time differs by age and sex in the United States from …

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Regulatory Elements Of Polyphosphate Biosynthesis, Marvin Qortez Bowlin Jan 2023

Regulatory Elements Of Polyphosphate Biosynthesis, Marvin Qortez Bowlin

All ETDs from UAB

Polyphosphate (polyP) is an ancient, conserved, inorganic biomolecule. Biological systems have adapted many functions for this high-energy molecule, ranging from immune regulation in mammals to gene regulation in prokaryotes. Of particular interest is its use in bacterial stress responses. Bacteria use polyP to resist hazardous environmental elements like toxic molecules or nutrient starvation. In many bacterial species, polyP is synthesized by polyphosphate kinases (PPKs). PPK – discovered in Escherica coli (E. coli) – hydrolyzes adenosine-5’-triphosphate (ATP) to synthesize polyP. Species that use PPK develop multiple pathogenic defects when PPK activity is impaired, including, among others, antibiotic susceptibility. There is no …

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I Would Be Shocked If Someone’S Not Depressed With That Diagnosis”: An In-Depth Exploration Of The Manifestation And Management Of Depression And Anxiety In Patients With Cancer, Carmen Rainey Brown Jan 2023

I Would Be Shocked If Someone’S Not Depressed With That Diagnosis”: An In-Depth Exploration Of The Manifestation And Management Of Depression And Anxiety In Patients With Cancer, Carmen Rainey Brown

All ETDs from UAB

Patients diagnosed with cancer experience depression and anxiety at higher rates compared to the general population. Most individuals diagnosed with cancer will experience symptoms of depression and anxiety at some point during their cancer trajectory and not seek care leaving their mental health conditions undiagnosed and untreated, which impact quality of life and cancer outcomes. Patient and providers perspectives are vital to understand the manifestation, care-seeking behaviors, and provider management of depression and anxiety in patients with cancer. This study sought to explore the manifestation of depression and anxiety among patients with cancer and their care seeking behaviors for mental …

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Conceptual Architecture For Digital Twin Implementation In A Smart City Framework, Wesley Conwell Jan 2023

Conceptual Architecture For Digital Twin Implementation In A Smart City Framework, Wesley Conwell

All ETDs from UAB

More than 9 billion people are expected to live on the planet in 2050, about two-thirds in cities. This substantial population growth in urban areas increases demands on cities' resources, services, and infrastructure. Hence, many cities leverage intelligent technologies to ensure urban communities' efficiency in integrating massive infrastructure components and services. Cities define this reconstruction of their operational framework as a smart city. Effective resource consumption management in a smart city integrative structure presents a problem with solutions concerning the distribution of city services. This dissertation aims to establish a conceptual framework to effectively manage resource consumption in a smart …

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Role Of Proteoglycan Forms Of The Type Iii Tgf-Β Receptor/Betaglycan In Tgf-Β Signaling In Ovarian Cancer Models, Alex Kwon-Bowers Choi Jan 2023

Role Of Proteoglycan Forms Of The Type Iii Tgf-Β Receptor/Betaglycan In Tgf-Β Signaling In Ovarian Cancer Models, Alex Kwon-Bowers Choi

All ETDs from UAB

Proteoglycans (PG) are defined as proteins with one or more covalently bound polysaccharides called glycosaminoglycan chains (GAG). PGs can either be present on the cell surface or in the extracellular matrix to mediate cellular homeostasis in normal physiology as well as exert profound roles in diseases such as cancer. PGs can interact with a host of proteins such as growth factors through their core protein and/or their GAG chains, serving as an accessory receptor to mediate signaling by binding to the ligands and altering ligand-signaling receptor binding, defined as a co-receptor function. Developmentally and in pathologies like cancer, TGF-β signaling …

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Enhancing Racial Identity And Promoting Academic Enablers In Black Adolescent Males Through Film Viewing, Carlos Napoleon Espinoza Jan 2023

Enhancing Racial Identity And Promoting Academic Enablers In Black Adolescent Males Through Film Viewing, Carlos Napoleon Espinoza

All ETDs from UAB

Among Black adolescent males, classroom discrimination is associated with lower academic performance, academic self-concept, and value placed on education. Although efforts aimed at eliminating racism and discrimination should be made, it is important to identify interventions that may mitigate the effects of discrimination on academic outcomes of Black adolescent males. Previously identified protective factors include positive racial socialization, positive racial identity, and Black role models. Thus, this project attempted to integrate these protective factors into a unified intervention approach in which Black role models deliver positive racial socialization messages to enhance positive racial identity and academic enablers through films. Preexisting …

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Transdiagnostic Symptom Clusters Among Idiopathic Pain And Fatigue Disorders, Chloe Lisette Jones Jan 2023

Transdiagnostic Symptom Clusters Among Idiopathic Pain And Fatigue Disorders, Chloe Lisette Jones

All ETDs from UAB

Background: There are no established etiologies, biomarkers, or approved treatments for myalgicencephalomyelitis/chronic fatigue syndrome (ME/CFS). It is thought that the ME/CFS criteria may be diagnosing individuals within a spectrum of different disease states, or even different diseases. There likely exist shared mechanisms across idiopathic pain and fatigue disorders, and diverse mechanisms underneath each individual diagnosis. The need to compare ME/CFS to similar, overlapping, and distinct disorders is a critical element in progressing our understanding of idiopathic pain and fatigue. Methods: A total of 2,731 comprehensive medical history and symptom reports were collected from respondents across the globe with a variety …

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Examining The Impact Of The Covid-19 Pandemic And Subsequent Vaccine Availability On Children’S Social Play Opportunities With A Focus On The Autism Community, Jenni Koehler Jan 2023

Examining The Impact Of The Covid-19 Pandemic And Subsequent Vaccine Availability On Children’S Social Play Opportunities With A Focus On The Autism Community, Jenni Koehler

All ETDs from UAB

Play, especially social play, is crucial to child development and impacts their cognitive, socioemotional, and motor growth. Children with an autism spectrum disorder (ASD) have social and motor impairments that act as barriers to their access to these critical social play opportunities. Those who are able to overcome these barriers through therapy have been shown to have better physical and mental outcomes. Unfortunately, the COVID-19 pandemic restricted social play opportunities for all children and disproportionately impacted children with ASD, further widening developmental gaps between them and their non-autistic peers. The development of the COVID-19 vaccine and its availability to children …

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Breast Cancer Metastasic Potential Mediated By Cd44/Hyaluronic Acid Signaling And Strains In The Tumor Microenvironment, Adam David Kotar Jan 2023

Breast Cancer Metastasic Potential Mediated By Cd44/Hyaluronic Acid Signaling And Strains In The Tumor Microenvironment, Adam David Kotar

All ETDs from UAB

Mechanical stimulation has been found to be an important regulator of nearly all biological processes, from maintaining normal homeostatic conditions to promoting pathological mechanisms of multiple diseases including cancer. While our knowledge of cancer continues to grow, our current models often lack the biophysical forces that are present in the body which could explain why numerous promising therapeutic agents discovered in research fail to translate into clinical efficacy. This study aims to demonstrate that breast cancer progression is mediated by strains in the tumor microenvironment (TME) in conjunction with trans-membranous glycoprotein receptor, CD44. There are many different sources of strain …

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Characterizing The Role Of Mapk Phosphatases In Age-Dependent Macrophage Dysfucntion And Increased Suceptiblity To Pneumonia In A Tnf-Dependent Manner, Katherine Lauren Kruckow Jan 2023

Characterizing The Role Of Mapk Phosphatases In Age-Dependent Macrophage Dysfucntion And Increased Suceptiblity To Pneumonia In A Tnf-Dependent Manner, Katherine Lauren Kruckow

All ETDs from UAB

Lower respiratory infections are the primary cause of infectious death among the elderly. One reason for this is ‘inflamm-aging,’ a chronic low-grade inflammatory state that develops with advanced age. Pertinently, our group has shown increases in TNF levels to be responsible for age-dependent macrophage dysfunction (ADMD) and, in turn, enhanced susceptibility to Streptococcus pneumoniae, the leading cause of community-acquired pneumonia. The underlying molecular mechanisms responsible, however, remain unclear. Following adoptive transfer of alveolar macrophages (AM) from aged (18+ months) or young (3-6 month) mice into young mice, followed by infection with S. pneumoniae, we found that aged AM were sufficient …

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New Heat Exchanger Modeling In The Passive Heat Removal System Of Vver-1200 Nuclear Power Plants, Bugrahan Mangan Jan 2023

New Heat Exchanger Modeling In The Passive Heat Removal System Of Vver-1200 Nuclear Power Plants, Bugrahan Mangan

All ETDs from UAB

The current work introduces an innovative methodology for modeling heat exchangers inside the passive heat removal system (PHRS) of water-water energetic reactor (VVER) nuclear power facilities. PHRS serves a crucial role in ensuring the secure and effective dissipation of residual heat produced during the shutdown of a reactor. Nevertheless, the current heat exchanger models exhibit deficiencies in terms of their thorough depiction of the geometric structure and thermal properties, hence limiting their precision and suitability for various applications.This study introduces a novel approach to modeling heat exchangers, with a specific emphasis on accurately representing complex geometric characteristics and including thermodynamic …

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Accuracy Of "Reading" Untraced Lateral Cephalometric Radiographs Among Practicing Orthodontists, Shannon Rea Jan 2023

Accuracy Of "Reading" Untraced Lateral Cephalometric Radiographs Among Practicing Orthodontists, Shannon Rea

All ETDs from UAB

Objective: To determine if orthodontic clinicians are able to ascertain diagnostic information from untraced lateral cephalometric radiographs. Materials and Methods: A survey consisting of 5 cases was presented to practicing orthodontists. Each case presented a lateral cephalometric radiograph and included ten questions requiring the respondent to make clinical judgments and approximations of the following variables: skeletal classification, maxilla and mandibular skeletal relationship, SNA, SNB, ANB, vertical skeletal classification, FMA, molar relationship, maxillary incisor proclination, and mandibular incisor proclination. 46 responses were collected and analyzed. Results: Case 3, the normodivergent, Skeletal Class I patient had the highest percentage of correct answers …

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