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2023

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Control Pepper Fusarium Wilting By Biocontrol Agent Trichoderma Harzianum And Chelated Iron Fe-Eddha, Ali Nasser Ali Al-Aamel, Bushra Subair Abdulsada Al-Maliky Dec 2023

Control Pepper Fusarium Wilting By Biocontrol Agent Trichoderma Harzianum And Chelated Iron Fe-Eddha, Ali Nasser Ali Al-Aamel, Bushra Subair Abdulsada Al-Maliky

Baghdad Science Journal

Sweet pepper (Capsicum annuum L.) is an economically important vegetable crop. Wilt disease caused by Fusarium oxysporum f. sp. capsici is a specific pathogen that affects the pepper. Four isolates of F. oxysporum f. sp. capsici Fo3, Fo6, Fo7 and Fo8 were obtained from diseased pepper plants that were collected from different pepper fields in Baghdad. Fo6 isolate that has high pathogenicity to pepper seeds, Trichoderma harzianum (Th) was tested in vitro against F. oxysporum f. sp. capsici showed a high inhibition rate for the isolate Fo6, the concentration of chelated iron Fe-EDDHA 0.5% reduced the radial growth of Fo6 …


Classification Of Iraqi Children According To Their Nutritional Status Using Fuzzy Logic, Hussein Ali Hasan, Mohammed Jasim Mohammed Dec 2023

Classification Of Iraqi Children According To Their Nutritional Status Using Fuzzy Logic, Hussein Ali Hasan, Mohammed Jasim Mohammed

Journal of Economics and Administrative Sciences

In this paper, we build a fuzzy classification system for classifying the nutritional status of children under 5 years old in Iraq using the Mamdani method based on input variables such as weight and height to determine the nutritional status of the child. Also, Classifying the nutritional status faces a difficult challenge in the medical field due to uncertainty and ambiguity in the variables and attributes that determine the categories of nutritional status for children, which are relied upon in medical diagnosis to determine the types of malnutrition problems and identify the categories or groups suffering from malnutrition to determine …


Employ The Knowledge Accumulation Of Human Resources In Strategic Performance, Anmar Muhammad Farag, Mohammed Yaseen Raheem Dec 2023

Employ The Knowledge Accumulation Of Human Resources In Strategic Performance, Anmar Muhammad Farag, Mohammed Yaseen Raheem

Journal of Economics and Administrative Sciences

The main purpose of this research is to diagnose the role of the Knowledge Accumulation of Human Resources KAHR in Strategic Performance SP, and for that, the research was applied to the represented sample by the administrative leaders consisting of (108) individuals distributed according to their positions and the organizational structure of the ministry. Correlations, effects, and benefits from generalizing the results in the field of research. The research involved a mixed-methods approach through two stages. During the first stage, the researcher gathered quantitative data from a questionnaire. The second stage gathered qualitative data to explore the survey results more …


The Role Of Digital Economy In Iraqi Economic Growth For The Period Of 2010-2022 (Analytical Study), Maryam Firas Abdullrada, Bushra Ali Wahaib Dec 2023

The Role Of Digital Economy In Iraqi Economic Growth For The Period Of 2010-2022 (Analytical Study), Maryam Firas Abdullrada, Bushra Ali Wahaib

Journal of Economics and Administrative Sciences

The research addresses the role of the digital economy in the growth of the Iraqi economy during the period from 2010 to 2022. The research is based on the hypothesis that the digital economy has become one of the primary growth drivers worldwide and has a close relationship with economic development. Therefore, the digital transformation in Iraq can accelerate bridging developmental gaps with other countries. It has become evident that the Iraqi economy suffers from structural imbalances for various reasons, hindering economic growth. These reasons include political and economic factors, as well as the absence of a well-thought-out policy to …


Math Anxiety Research Paper, Daniella M. Tartaro Dec 2023

Math Anxiety Research Paper, Daniella M. Tartaro

Transformations

Math anxiety can be characterized as feelings of apprehension or distress that individuals experience when faced with tasks or activities associated with mathematics. Due to its prevalence, math anxiety is a growing issue for teachers who seek to uplift and prioritize the comfort, well-being and success of their students. Failure to address math anxiety can significantly hinder a student’s learning, lower their academic performance, and negatively cloud their overall attitude towards mathematics. In gathering and sorting resources associated with prevailing positions regarding math apprehension, this paper aims to explore math anxiety’s impact on students' learning, and the benefit of collaborative …


Cooperative Extension Programming For Early Care And Education Professionals During The First Year Of The Covid-19 Pandemic: Evidence From A National Survey Of Extension Systems, Katherine Speirs, Azriella Friedman, Courtney Luecking, Kyleigh Brown Dec 2023

Cooperative Extension Programming For Early Care And Education Professionals During The First Year Of The Covid-19 Pandemic: Evidence From A National Survey Of Extension Systems, Katherine Speirs, Azriella Friedman, Courtney Luecking, Kyleigh Brown

Journal of Human Sciences and Extension

Cooperative Extension Systems (CESs) provide programming to early care and education (ECE) professionals. The COVID-19 pandemic significantly impacted the needs of ECE professionals. The purpose of this study was to document how CESs helped ECE professionals respond to the pandemic during its first year and how Extension programming was altered in response to the pandemic. Between March and June 2020, representatives from all 87 CESs in the 50 U.S. states; Washington, DC; and six U.S. territories were invited to complete an online survey that included six questions about the pandemic. We received responses from 43 CESs (49% response rate). The …


Profiles Of Youth Citizenship: A Cluster Analysis Of Ethical Factors, Demographics, And Problem-Solving Disposition, Sarah Bush, Rick Rudd, Curt Friedel, Thomas Archibald, Kerry Redican Dec 2023

Profiles Of Youth Citizenship: A Cluster Analysis Of Ethical Factors, Demographics, And Problem-Solving Disposition, Sarah Bush, Rick Rudd, Curt Friedel, Thomas Archibald, Kerry Redican

Journal of Human Sciences and Extension

Youth have the capacity to drive positive change in their communities through active and engaged citizenship (AEC). Teen leadership programs provide youth with opportunities to develop the skills necessary to participate as partners in community problem-solving efforts. Situated in relational developmental systems metatheory, this study examined how cluster membership based upon demographic characteristics, ethical factors, and problem-solving disposition impacted AEC. The findings indicated significant differences between clusters for AEC, civic duty, and civic skills. These differences were predominately observed through membership in long-term or short-term leadership programs, gender, enrollment in honors/AP courses, ethical views, and problem-solving disposition. Youth leadership practitioners …


A Snapshot In Time: Consumer Behavior At The Start Of Covid-19, Michelle L. Childs, Christopher Sneed, Ann A. Berry, Sejin Ha Dec 2023

A Snapshot In Time: Consumer Behavior At The Start Of Covid-19, Michelle L. Childs, Christopher Sneed, Ann A. Berry, Sejin Ha

Journal of Human Sciences and Extension

During the early stages of the coronavirus pandemic, consumers faced challenges related to obtaining household items due to shortages and limitations in shopping. Researchers from the University of Tennessee conducted a national, web-based consumer survey of 300 consumers in late April 2020 to better understand consumer behavior, shopping patterns, and demand shifts for goods and services. Major findings demonstrate that consumers have increased shopping for essential products from brick-and-mortar national chains, avoided brick-and-mortar small businesses, and have chosen to shop more by themselves, often choosing to forgo spending from across all product categories, compared to prior to the pandemic. Additionally, …


A Study Of The Snd1/Prmt5 Axis In Liver Cancer By Genetic Mouse Models, Tanner Wright, Tanner Wright Dec 2023

A Study Of The Snd1/Prmt5 Axis In Liver Cancer By Genetic Mouse Models, Tanner Wright, Tanner Wright

Dissertations and Theses (Open Access)

Arginine methylation is an essential post-translational modification (PTM) in cells. Protein arginine methyltransferase 5 (PRMT5) is the primary enzyme that catalyzes symmetric dimethyl arginine (SDMA) and requires methylosome protein 50 (MEP50) for stability and enzymatic activity which are necessary for life and development. Effector proteins bind different types of PTM’s to facilitate signaling. Staphylococcal nuclease Tudor domain containing 1 (SND1) is an effector that specifically binds SDMA via its single C-terminal Tudor domain. Both SND1 and PRMT5 have been implicated in hepatocellular carcinoma (HCC). SND1 has been confirmed as a driver of HCC using genetically engineered mouse models (GEMMs), though, …


Respectful Workplace Policy To Conceive A Security Consciousness And Gender Equality As An Implementation Of Akhlak Core Values In State-Owned Enterprises Environment, Endang Susilowati, Erwin Susanto Sadirsan Dec 2023

Respectful Workplace Policy To Conceive A Security Consciousness And Gender Equality As An Implementation Of Akhlak Core Values In State-Owned Enterprises Environment, Endang Susilowati, Erwin Susanto Sadirsan

Journal of Terrorism Studies

A safe work environment, mutual respect, freedom from discrimination, harassment, violence, gender inequality, discrimination of women is highly coveted in the Indonesian work environment. In State-Owned Enterprises there are still issues of harassment, gender inequality, violence, and women's opportunities to become leaders in the workplace. In 2021, the number of women leaders in workplace is still below 10%. The Ministry of State-Owned Enterprises is aiming to increase the representation of women in the Board of Commissions or Executives, and one level below the Board of Executives by 25% in 2023.

The purpose of this research is to analyse women's issues …


A Comparison Between A Terrorist Leader And A Lone-Wolf Operative In Bangladesh, Fatema Islam Dec 2023

A Comparison Between A Terrorist Leader And A Lone-Wolf Operative In Bangladesh, Fatema Islam

Journal of Terrorism Studies

The article compares the biography and terrorist portrait of two terrorists of Bangladesh: Mufti Abdul Hannan, a pioneer leader of the prominent terrorist organization Huji-B, and a lone wolf operative named Faizul Hasan. The study reveals the existence of the multifaceted dynamics of the leader (Mufti) and lone wolf (Faizul) encompassing organizational affiliation, operational independence, radicalization processes, motivations, objectives, and the scale of their operations. The study also finds that the pattern of operation of a terrorist leader (Mufti) and the lone wolf terrorist (Faizul) differed significantly in terms of planning, execution, and level of organizational support. While the terrorist …


Coverage Of Kidnapping In North-West Nigeria:An Analysis Of Daily Trust And The Guardian Newspapers, Amina Salisu Mohammed Dec 2023

Coverage Of Kidnapping In North-West Nigeria:An Analysis Of Daily Trust And The Guardian Newspapers, Amina Salisu Mohammed

Journal of Terrorism Studies

The study examined the coverage of kidnapping in North-West Nigeria by looking at the extent of coverage, prominence and major sources of news found in the stories in Daily Trust and The Guardian newspapers for the period of two years using content analysis research design. The findings indicated little attention to the interpretative role of the mass media, low prominence and too much reliance on Government/official news sources in reporting kidnapping in North-West Nigeria.

Keywords: Kidnapping, Terrorism, Insecurity, Coverage, Armed Banditry


Security Challenges And The Survival Of Democracy In Nigeria: An Assessment Of Niger East Senatorial District, Niger State, Yahuza Danjuma Izom Dec 2023

Security Challenges And The Survival Of Democracy In Nigeria: An Assessment Of Niger East Senatorial District, Niger State, Yahuza Danjuma Izom

Journal of Terrorism Studies

The study assessed security challenges in relation to survival of democracy in Nigeria with focus on Niger East Senatorial District. The methodology adopted for the study is descriptive research. The population of the study was drawn from nine local government areas that constituted the district with a population of 1,513,469 (NPC, 2006). Sample size of 380 was used and the sampling technique was simple random sampling technique. Questionnaire was used as the research instrument which was well structured in two parts. Part (A) is the biodata of the respondent and part (B) was on the subject matter of the research …


Ideological Parameters For Deradicalization Programs To Measure Changes In Terrorist Ideology In Indonesia, Yudi Zulfahri, Aldi Nur Fadil Auliya Dec 2023

Ideological Parameters For Deradicalization Programs To Measure Changes In Terrorist Ideology In Indonesia, Yudi Zulfahri, Aldi Nur Fadil Auliya

Journal of Terrorism Studies

The paper analyzes the inefficiency of the Deradicalization strategy implemented by The National Counter Terrorism Agency (BNPT), causing the issue of recidivist terrorism in Indonesia. Although the occurrence of recidivism is common in various crimes, it poses unique challenges in terrorism cases, given that the government has allocated a specific budget and established a special agency, BNPT, to tackle terrorism-related issues. The high recidivism rate in terrorism cases has prompted public concern and criticism regarding the effectiveness of Deradicalization programs. Despite the ongoing debate, this paper argues that the success or failure of Deradicalization programs cannot be measured simply by …


Contra Radicalism Through The Interpreting Verse Of Jihad (Case Study On Nu Online Platform), Kholifah Rahmawati, Heriyanto Heriyanto Dec 2023

Contra Radicalism Through The Interpreting Verse Of Jihad (Case Study On Nu Online Platform), Kholifah Rahmawati, Heriyanto Heriyanto

Journal of Terrorism Studies

This research attempts to map counter-radicalism in religious-based efforts carried out by a religious organization through digital platforms. With a virtual ethnographic model that focuses on text analysis, it is known that NU Online has carried out counter-radicalism through a religious interpretation approach. By targeting jihad verses, counter-radicalism is done in three ways, namely, deconstruction of the meaning of jihad, reconstruction of the meaning of jihad, and counter-narrative of jihad verses with peace verses. Apart from that, NU Online is also increasing its influence in the digital space by strengthening its narrative and identity as a moderate group with national …


Power Projection And Counter-Terrorism: Strategies For Small States Like Brunei Darussalam, Brice Tseen Fu Lee, Gulshan Bibi Ms Dec 2023

Power Projection And Counter-Terrorism: Strategies For Small States Like Brunei Darussalam, Brice Tseen Fu Lee, Gulshan Bibi Ms

Journal of Terrorism Studies

This study delves into the intricacies of power projection strategies and counter-terrorism measures, emphasizing their relevance to small states, with a specific focus on Brunei Darussalam. Using a dual matrix model, the research categorizes various strategies based on risk-reward parameters, offering a structured insight into potential approaches these states can employ against potential aggressors. The counter-terrorism matrix is the initial focal point, recognizing the contemporary significance of terror threats and their unique challenges for small nations. Subsequently, the power projection matrix offers a broader view of defense tactics beyond counter-terrorism. By synthesizing information from primary academic sources, the study aims …


Light & Faith: December 2023, Taylor University Dec 2023

Light & Faith: December 2023, Taylor University

Light & Faith

No abstract provided.


Adapting Black Culture: Without The Black Experience, Bakhita Solenyanu Dec 2023

Adapting Black Culture: Without The Black Experience, Bakhita Solenyanu

English

No abstract provided.


Learning About Street Harassment On Transit: A Survey Instrument For Transit Agencies, Asha Weinstein Agrawal, Jon Canapary, Carol Anne Caroll, Tam J. Guy, Anastasia Loukaitou-Sideris Dec 2023

Learning About Street Harassment On Transit: A Survey Instrument For Transit Agencies, Asha Weinstein Agrawal, Jon Canapary, Carol Anne Caroll, Tam J. Guy, Anastasia Loukaitou-Sideris

Mineta Transportation Institute

This study was conducted in accordance with California Senate Bill 1161 (2022), legislation that directed the Mineta Transportation Institute to develop a reliable, easy-to-use survey instrument for collecting information from public transit passengers about the extent, location, and characteristics of any street harassment they experience. Although the legislation is focused on large California transit agencies, the study findings are equally relevant to smaller agencies and agencies outside the state. To develop the recommended questionnaire, we reviewed literature about street harassment, analyzed transit passenger surveys to explore the questions asked about safety and harassment, received feedback on iterative drafts of the …


Deep Learning, Machine Learning, Or Statistical Models For Weather-Related Crash Severity Prediction, Abimbola Ogungbire, Panick Kalambay, Hardik Gajera, Srinivas S. Pulugurtha Dec 2023

Deep Learning, Machine Learning, Or Statistical Models For Weather-Related Crash Severity Prediction, Abimbola Ogungbire, Panick Kalambay, Hardik Gajera, Srinivas S. Pulugurtha

Mineta Transportation Institute

Nearly 5,000 people are killed and more than 418,000 are injured in weather-related traffic incidents each year. Assessments of the effectiveness of statistical models applied to crash severity prediction compared to machine learning (ML) and deep learning techniques (DL) help researchers and practitioners know what models are most effective under specific conditions. Given the class imbalance in crash data, the synthetic minority over-sampling technique for nominal (SMOTE-N) data was employed to generate synthetic samples for the minority class. The ordered logit model (OLM) and the ordered probit model (OPM) were evaluated as statistical models, while random forest (RF) and XGBoost …


Prevalence Of Substance Use Among Lesbian, Gay, And Bisexual High School Students In 2019 Vs. 2021, Jordyn Lee, Elisabeth Hayes, Adam Wyatt Dec 2023

Prevalence Of Substance Use Among Lesbian, Gay, And Bisexual High School Students In 2019 Vs. 2021, Jordyn Lee, Elisabeth Hayes, Adam Wyatt

Nursing & Health Sciences Research Journal

Background: Studies suggest that LGBTQ+ (lesbian, gay, bisexual, transgender, queer/questioning, plus) youth are at increased risk of engaging in alcohol and substance use. The COVID-19 pandemic forced many students to isolate in 2020 and 2021, and the impacts of this have been purported to be detrimental. This study examines the prevalence of alcohol and substance use among lesbian, gay, and bisexual (LGB) U.S. high school students before the pandemic in 2019 versus 2021. Methods: This cross-sectional descriptive study used results from the 2019 Youth Risk Behavior Survey (YRBS) and the 2021 Adolescent Behavior and Experiences Survey (ABES). The 2019 YRBS …


Implementation Of The Resuscitation Quality Improvement Program In A System Of Hospitals: A Map For Success, Claudia C. Sabogal-Rodriguez, John Mouw Dec 2023

Implementation Of The Resuscitation Quality Improvement Program In A System Of Hospitals: A Map For Success, Claudia C. Sabogal-Rodriguez, John Mouw

Nursing & Health Sciences Research Journal

Introduction: To prevent cardiopulmonary resuscitation (CPR) skills decay, the International Consensus on Resuscitation suggested retraining every three to six months. Current retraining practices nationwide exceed one to two years, suggesting that clinical staff's CPR skills are rarely at optimum proficiency. The Resuscitation Quality Improvement (RQI) program offers skills decay prevention through quarterly sessions. This manuscript addresses the challenges and opportunities of implementing the RQI program in a hospital system to increase CPR skills quality and cost-savings. Purpose & Methods: This manuscript describes the challenges and opportunities of implementing the RQI program as a quality improvement initiative in a system of …


Allied Health Scholars Program: Addressing Workforce Shortage And Talent Pipeline Through Educational Programs, Carolina Perticari, Melissa R. Maguina, Lorell Bergolla, Maria Gauthreaux, Aleister Avila, John Mouw, Alwyn Leiba, Bryan Stewart, Agueda Hernandez, Zuanel Diaz Dec 2023

Allied Health Scholars Program: Addressing Workforce Shortage And Talent Pipeline Through Educational Programs, Carolina Perticari, Melissa R. Maguina, Lorell Bergolla, Maria Gauthreaux, Aleister Avila, John Mouw, Alwyn Leiba, Bryan Stewart, Agueda Hernandez, Zuanel Diaz

Nursing & Health Sciences Research Journal

No abstract provided.


Laypeople’S Perceptions Of Secondary Trauma In Criminal Justice System Workers, Mariah Simone Dec 2023

Laypeople’S Perceptions Of Secondary Trauma In Criminal Justice System Workers, Mariah Simone

Student Theses

This study sought to examine laypeople’s perceptions of secondary trauma experienced by criminal justice system workers. Specifically, how these perceptions of exposure to secondary trauma influence laypeople’s perceptions of those workers’ memory ability. To investigate these perceptions, we collected data from 70 participants in a Pilot Study, 383 participants in Study 1, and 408 participants in a Replication of Study 1 regarding their perceptions of secondary trauma in various criminal justice careers. Specifically, using a modified Autobiographically Memory Questionnaire to examine how their perceptions of secondary trauma exposure affects their perceptions of memory ability in these workers. We also collected …


Development Of Novel Methods To Study Host-Microbe Interactions In The Larval Zebrafish Gastrointestinal Tract, Anh K. Trinh Nguyen Dec 2023

Development Of Novel Methods To Study Host-Microbe Interactions In The Larval Zebrafish Gastrointestinal Tract, Anh K. Trinh Nguyen

Dissertations and Theses (Open Access)

The dynamic nature and inaccessible location of the intestine pose significant challenges to the study of intestinal physiology and pathology. Zebrafish larvae, possessing optical transparency and genetic tractability, offer an accessible and clinically relevant model for investigating dynamic events in the intestine via time-lapse imaging. In the first part of this work, I discuss our efforts to optimize the parameters of a foodborne infection assay using paramecia as a vehicle. This method provides an effective, high-throughput alternative to infection via immersion or oral gavage, and replicates the most common route of transmission of gastrointestinal (GI) infection in humans. The foodborne …


Telomeric Regulation Of Chromosomal Instability In Colorectal Cancer, Kyle Labella, Kyle A Labella Dec 2023

Telomeric Regulation Of Chromosomal Instability In Colorectal Cancer, Kyle Labella, Kyle A Labella

Dissertations and Theses (Open Access)

Telomere dysfunction drives chromosomal instability (CIN) during the transition from benign adenoma to malignant adenocarcinoma. While CIN provides a mutator mechanism for cancer-relevant genomic events, its role in shaping tumor biology during carcinogenesis is not well understood. Here, we explored the molecular and biological impact of telomere dysfunction and associated CIN in vivo in a faithful model of CRC. In vivo lineage tracing revealed that CIN increased neoplastic cell competition and clonal expansion through accelerated differentiation of neighboring stem cells, resulting in increased number of adenomas and decreased survival in CIN-high Apcmin mice. Mechanistically, CIN represses EZH2 leading to …


Role Of The Immune System In The Modulation Of The Mmr-Deficient Intestinal Stem Cell Niche, Shepard Conner Dec 2023

Role Of The Immune System In The Modulation Of The Mmr-Deficient Intestinal Stem Cell Niche, Shepard Conner

Dissertations and Theses (Open Access)

Mismatch Repair (MMR) is a crucial DNA repair system to maintain genomic integrity in cells that is integrated by specific genes including MLH1, MSH2, MSH6, and PMS2. These genes play a critical role in repairing errors that occur in base pairing by stabilizing the genetic material. When the MMR system fails to correct those errors, MMR deficiency occurs where monoallelic mutations in the MMR genes result in a condition known as Lynch Syndrome (LS). LS makes up approximately 3% of all colorectal cancer (CRC) and is regarded as a hereditary form of CRC, which progresses from MMR-deficient …


Development Of A Remote Dosimetric Audit Framework For Carbon Therapy, Paige Taylor Dec 2023

Development Of A Remote Dosimetric Audit Framework For Carbon Therapy, Paige Taylor

Dissertations and Theses (Open Access)

Carbon ion therapy is available at over a dozen institutions around the world and is being employed for treatment of cancer. The increased biological effect of carbon compared to conventional photon-based radiotherapy holds promise for the therapeutic benefit in historically radioresistant tumors. While ion chamber dosimetry has been used for day-to-day clinical measurements of absorbed dose, there are few options for remote dosimetry. The availability of such tools would support the development of a robust remote audit program for carbon ion therapy.

The Imaging and Radiation Oncology Core (IROC) conducts remote audits of photon and proton therapy. These audits are …


Mortality And Morbidity Among Individuals With Hypertension Receiving A Diuretic, Ace Inhibitor, Or Calcium Channel Blocker: A Secondary Analysis Of A Randomized Clinical Trial, Jose-Miguel Yamal, Journey Martinez, Mikala C Osani, Xianglin L Du, Lara M Simpson, Barry R Davis Dec 2023

Mortality And Morbidity Among Individuals With Hypertension Receiving A Diuretic, Ace Inhibitor, Or Calcium Channel Blocker: A Secondary Analysis Of A Randomized Clinical Trial, Jose-Miguel Yamal, Journey Martinez, Mikala C Osani, Xianglin L Du, Lara M Simpson, Barry R Davis

Faculty, Staff and Student Publications

IMPORTANCE: The long-term relative risk of antihypertensive treatments with regard to mortality and morbidity is not well understood.

OBJECTIVE: to determine the long-term posttrial risk of primary and secondary outcomes among trial participants who were randomized to either a thiazide-type diuretic, calcium channel blocker (CCB), or angiotensin-converting enzyme (ACE) inhibitor with up to 23 years of follow-up.

DESIGN, SETTING, AND PARTICIPANTS: This prespecified secondary analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), a multicenter randomized, double-blind, active-controlled clinical trial, followed up with participants aged 55 years or older with a diagnosis of hypertension and at …


A Double-Robust Test For High-Dimensional Gene Coexpression Networks Conditioning On Clinical Information, Maomao Ding, Ruosha Li, Jin Qin, Jing Ning Dec 2023

A Double-Robust Test For High-Dimensional Gene Coexpression Networks Conditioning On Clinical Information, Maomao Ding, Ruosha Li, Jin Qin, Jing Ning

Faculty, Staff and Student Publications

It has been increasingly appealing to evaluate whether expression levels of two genes in a gene coexpression network are still dependent given samples' clinical information, in which the conditional independence test plays an essential role. For enhanced robustness regarding model assumptions, we propose a class of double-robust tests for evaluating the dependence of bivariate outcomes after controlling for known clinical information. Although the proposed test relies on the marginal density functions of bivariate outcomes given clinical information, the test remains valid as long as one of the density functions is correctly specified. Because of the closed-form variance formula, the proposed …