Digital Commons Network^™

Leveraging Advanced Analytics In The Pharmaceutical Industry, Patrick O'Sullivan

Level 3

This article is a transcribed and lightly edited version of Patrick O’Sullivan’s oral presentation to a seminar hosted on 1 June 2023 by the Pharmaceutical Regulatory Science Team (PRST), TU Dublin, titled ICH Q9(R1): The Next Frontier – An audience with international thought leaders exploring how the effective use of knowledge can enhance QRM outcomes to benefit the patient. Patrick presented an overview of how one could leverage advanced analytics in the pharmaceutical Industry.

Valerie Mulholland On Improving Rbdm Effectiveness, Valerie Mulholland

Level 3

No abstract provided.

Speaker Bios

Level 3

No abstract provided.

Ipq Bibliography Pac Km Qrm 2010 - 2023

Level 3

No abstract provided.

Analisis Pengaruh Kebijakan Fiskal Dan Moneter Terhadap Tingkat Pengembalian Saham Indonesia Tahun 2015-2019, Annisa Ramadhanti, Muthia Pramesti

Jurnal Administrasi Bisnis Terapan

This study aims to analyze the effect of fiscal and monetary policies projected by variables of state revenue income, government spending, inflation rates, and interest rates on the projected rate of return on stocks in Indonesia through returns or returns on the JCI. The data used is secondary data taken from various source in the form of monthly data from 2015 to 2019. The analytical method used in this study is multiple regression analysis to see the effect of all the independent variables on the dependent variable. The results of the study show that the variables of fiscal policy in …

Operating Fund Budget/ Expenditure Detail Report 2023-24, Csusb Budget Office

University Budget Office records

No abstract provided.

Maurer Environmental Law Expert Is Lead Author On Science Insights Policy Forum Article, James Owsley Boyd

Keep Up With the Latest News from the Law School (blog)

Environmental champions and conservationists will mark the 50th anniversary of the Endangered Species Act later this month. That is the law requiring federal agencies to use all methods necessary to prevent extinctions and ensure that federal actions not jeopardize the continued existence of species on the brink of disappearing from the face of the Earth.

In the leadup to the December 27th anniversary, several publications have begun examining the Act’s history and impact over five decades.

Science, the world’s third-most influential scholarly journal based on Google Scholar citations, invited experts from around the country to look ahead as well …

Images Of Maps And Connotative Tendencies In Early Republican America, Kerr Houston

Art Inquiries

No abstract provided.

Outsourcing Voting To Ai: Can Chatgpt Advise Index Funds On Proxy Voting Decisions?, Chen Wang

Fordham Journal of Corporate & Financial Law

Released in November 2022, Chat Generative Pre-training Transformer (“ChatGPT”), has risen rapidly to prominence, and its versatile capabilities have already been shown in a variety of fields. Due to ChatGPT’s advanced features, such as extensive pre-training on diverse data, strong generalization ability, fine-tuning capabilities, and improved reasoning, the use of AI in the legal industry could experience a significant transformation. Since small passive funds with low-cost business models generally lack the financial resources to make informed proxy voting decisions that align with their shareholders’ interests, this Article considers the use of ChatGPT to assist small investment funds, particularly small passive …

Relative Comparison Of Modern Computing To Computer Technology Of Ages, Iwasan D. Kejawa Dr., Hailly Rubio Ms.

School of Computing: Faculty Publications

Abstract

Abstract

Are there differences and similarities between the computer technology of today and yesterdays. Research had shown that there had been tremendous improvements from the computers of ages (traditional Computers) as we enter the 21st century. Both the physicality and the functionalities of computers have changed but some remain the same. The memory capacity and functions have changed, but all are still based on the old concepts of yesteryears.

The Investigation Of The Antimicrobial And Biofilm-Disrupting Properties Of Synthesized Hemibastadin Derivatives, Antonio Harvey, Andrew A. Yeagley

Longwood Senior Thesis Proposal

We want to investigate structural changes to the core hemibastadin structure while attempting to make these derivatives biologically safer. Since these modifications have never been done before, we will need to design a synthesis of these new molecules. Due to the nature of the molecules (dimers), a divergent synthesis that allows for the creation of both halves simultaneously seems most appropriate. A successful synthesis of these compounds will allow us to further investigate these derivatives for their antimicrobial and biofilm-disrupting properties.

Consequences Of Spatial Structure In Soil–Geomorphic Data On The Results Of Machine Learning Models, Daehyun Kim, Insang Song, Lorrayne Miralha, Daniel R. Hirmas, Ryan W. Mcewan, Tom G. Mueller, Pavel Samonil

Biology Faculty Publications

In this paper, we examined the degree to which inherent spatial structure in soil properties influences the outcomes of machine learning (ML) approaches to predicting soil spatial variability. We compared the performances of four ML algorithms (support vector machine, artificial neural network, random forest, and random forest for spatial data) against two non-ML algorithms (ordinary least squares regression and spatial filtering regression). None of the ML algorithms produced residuals that had lower mean values or were less autocorrelated over space compared with the non-ML approaches. We recommend the use of random forest when a soil variable of interest is weakly …

Identification Of Scientific Argumentation Ability Of High School Students On Optical Instrument Material, Rais Muktamar Amin, Parno Parno, Sentot Kusairi, Marlina Ali

Jurnal Pendidikan Sains

Optical instruments play a crucial role in physics education, providing essential material for students to understand complex concepts. This study aims to evaluate the scientific argumentation abilities of high school students regarding optical instruments. Conducted as a quantitative descriptive study, the research involved 60 eleventh-grade MIPA students from SMA Laboratorium UM. The research instrument was a scientific argumentation test comprising 12 essay questions, designed according to the Toulmin Argumentation Pattern (TAP) adaptation indicators, with a reliability coefficient of 0.332. Student responses were classified into five levels of scientific argumentation based on the TAP model, as developed by Sampson, Enderle, and …

Identifying Students’ Incorrect Common-Sense Knowledge In Forces And Motion: Recommendations For Developing Computer-Based Learning Media, Ahmad Ridlotul Adha, Sutopo Sutopo, Nasikhuddin Nasikhuddin

Jurnal Pendidikan Sains

Conceptual understanding is a crucial area in physics education research, focusing on students’ comprehension of fundamental principles. Force and motion, integral topics within this field, are inherently linked to students’ daily experiences. Numerous studies have identified the persistence of common sense knowledge among students. This research presents a literature review aimed at identifying such consistently held misconceptions. We analyzed 17 papers sourced from Publish or Perish 8, Google Scholar, and Scopus. Our analysis revealed that the concepts of impetus and active force are the most persistent forms of common sense knowledge, influenced by real-life experiences. Additionally, students’ difficulties with kinematics …

Analyzing Physics Students’ Misconceptions About Simple Electrical Circuits, Sapta Adiguna, Shinta Dewi Susanti, Sentot Kusairi, Iwan Setiawan

Jurnal Pendidikan Sains

This study investigates the prevalence and types of misconceptions among first-year Physics Education students regarding simple electrical circuits using the Simple Electric Circuits Diagnostic Test (SECDT). Employing a quantitative descriptive approach, the research analyzes responses from a sample of 42 students, selected through convenience sampling. The SECDT, a three-tier diagnostic instrument with a reliability of 0.69, identifies student misconceptions by categorizing responses into scientific knowledge, misconceptions, no understanding, and lack of knowledge. The results indicate significant gender differences in the types and prevalence of misconceptions. Male students exhibited a higher percentage of misconceptions (77.5%) compared to female students (62.8%). Notably, …

The Influence Of Predict, Observe, And Explain (Poe) Learning Accompanied By Formative Assessment On Misconceptions And Mastery Of Students’ Concepts Of Temperature And Heat Material, Ahmad Ilmar, Sentot Kusairi, Khusaini Khusaini

Jurnal Pendidikan Sains

High misconceptions and students’ mastery of concepts that are low enough are detected in temperature and heat material. To overcome this, teachers must apply learning strategies that are able to actively involve students in observation activities, namely the POE learning strategy. However, POE learning is not always easy to apply, students are still weak in communicating the results of their experiments. Therefore, a way is needed that helps students during the learning process to be more confident and not afraid when asked to argue, namely with formative assessment. POE learning accompanied by formative assessment aims to enable students to understand …

The Effect Of The Beruang Game On Symbolic Thinking Ability And Logical-Mathematical Intelligence, Alif Kurin’Ain, Hermanto Hermanto

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Meneliti pengaruh permainan Beruang (Number Hunting) terhadap kemampuan berpikir simbolik dan kecerdasan logis-matematis anak PAUD. Hasil menunjukkan peningkatan signifikan pada kedua aspek dibanding kelompok kontrol.

Analyzing A Smartphone Battle Using Bass Competition Model, Maila Hallare, Alireza Hosseinkhan, Hasala Senpathy K. Gallolu Kankanamalage

CODEE Journal

Many examples of 2x2 nonlinear systems in a first-course in ODE or a mathematical modeling class come from physics or biology. We present an example that comes from the business or management sciences, namely, the Bass diffusion model. We believe that students will appreciate this model because it does not require a lot of background material and it is used to analyze sales data and serve as a guide in pricing decisions for a single product. In this project, we create a 2x2 ODE system that is inspired by the Bass diffusion model; we call the resulting system the Bass …

Role Of Urban Parks In Carbon Sequestration– A Case Study Of Safari Park, Karachi, Pakistan, Amna Bano, Minzah Shehzad, Hasnain Kazmi, Jamshaid Iqbal

Journal of Bioresource Management

Urban parks besides their recreational use can be the potential source of climate mitigation through carbon sequestration. Present study aims to identify the carbon sequestration potential of Safari Park which is by far the largest public park of Karachi established in 1970 covering an area of 0.72 km². A total of 153 individual trees belonging to 25 species and 14 families were included in the study. Five dominant species with highest Important Value Index (IVI) were Cocos nucifera (14.62 %), Azadirachta indica (14.21 %), Guaiacum officinale (9.93 %), Washington robusta (9.31 %) and Delonix regia (7.11 %). The …

Sustainable Food House Area (Sfha): Analysis Of Community Knowledge And Behavior, Delvi Adri, Mimien Henie Irawati, Sueb Sueb

Jurnal Pendidikan Sains

This research aimed to assess the knowledge and behavior of the community regarding the Sustainable Reserve Food Garden (SRFG) program. The study was conducted in July 2016 in Jorong Lubuk Agam, Kenagarian Ampang Kuranji Koto Baru, Dharmasraya, West Sumatra. Utilizing a descriptive quantitative approach, data were collected using Accidental Random Sampling, involving 33 heads of families as respondents. The findings revealed that community knowledge and behavior related to the SRFG program were generally insufficient, with 44.1% and 47.27% of respondents, respectively, demonstrating a lack of understanding and practice. The study concludes that approximately one-third of the population has limited knowledge …

2023 - Tennessee Annual Climate Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Monthly Reports

No abstract provided.

Measuring The Performance Of Sdgs In Provincial Level Using Regional Sustainable Development Index, Nurafiza Thamrin, Ika Yuni Wulansari, Puguh Bodro Irawan

Journal of Environmental Science and Sustainable Development

Measuring the national and sub-national progress in achieving such globally adopted development agendas as Sustainable Development Goals (SDGs) is particularly challenging due to data availability and compatibility of indicators to measure SDGs, especially in Indonesia. This paper attempts to measure the performance of sustainable development at the regional level in Indonesia by newly constructing a multidimensional composite index called the Regional Sustainable Development Index (RSDI). RSDI comprises four dimensions, covering comprehensive economic, social, environmental, and governance indicators. By applying factor analysis, the paper assesses the uncertainty of RSDI and the sensitivity of its composing indicators, then further investigates the relationship …

Developing Team Assisted Individualization-Based Student Worksheets To Improve Learning Outcomes And Mathematical Collaboration Skills, Hermanto Hermanto, Mita Akbar Sukmarini

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Mengembangkan LKS berbasis Team Assisted Individualization (TAI) pada materi matriks untuk siswa SMK. Hasil menunjukkan LKS sangat valid, praktis, dan efektif meningkatkan hasil belajar serta kemampuan kolaborasi matematis.

Preface, Anne Greene, Martin Lipa, Bill Paulson

Level 3

No abstract provided.

Regulators Are Exploring With Industry How To Strengthen Quality Risk Management Practices, With Revision Of Ich Q9 A Key Focal Point, ( Ipq )

Level 3

No abstract provided.

Links To Prst Past Monographs And Level 3 Special Editions

Level 3

No abstract provided.

Do Characteristics Of Board Affect Sustainable Finance Disclosure? Evidence: Asean Banking Industry, Reysvana Rukmana Cakti, Y Anni Aryani

Jurnal Akuntansi dan Keuangan Indonesia

Sustainability is an essential aspect of previous investigations on the relationship between business practices and sustainability commitments. These investigations showed how positive changes in this context have guided the banking system toward embracing sustainable finance. Therefore, the current study aimed to investigate the effect of board characteristics on sustainable finance disclosure within ASEAN banking industry, using a panel data regression model. The results showed that only board size had a positive and significant effect on sustainable finance disclosure. Meanwhile, variables such as board gender, board education, and foreign board was reported to be insignificant. This study provided valuable insight into …

The Clarity Of Business Models In Integrated Accounting Reports, Gabriel Donleavy

Jurnal Akuntansi dan Keuangan Indonesia

In this study, 664 students enrolled in accounting theory courses at both the undergraduate and postgraduate levels at the University of New England were tasked with the assignment of critically assessing the decision usefulness and understandability of 2 to 4 integrated accounting reports. A key aspect of their analysis involved a critical examination of how the accounting reports conveyed the business models employed by the respective companies. In the case of consolidated reports, students were expected to observe distinct business models for each segment of the group or identify a robust rationale if only one model was presented. A team …

Covalent Inhibition Of Enzyme Sortase A As A New Pathway Against Bacterial Resistance Of Staphylococcus Aureus, Umyeena Bashir

Master's Theses

The continued rise of antibiotic-resistant bacteria, such as MRSA (methicillin-resistant Staphylococcus aureus), has made the discovery of novel antibiotics critical. While bacteriostatic and bactericidal antibiotics inevitably exert evolutionary pressure on bacteria to develop resistance, small molecules that target mechanisms of bacterial virulence present a promising alternative for treatment. Sortase A (Srt A), a cysteine protease of S. aureus, promotes bacterial virulence by covalently attaching proteins such as pilin to the bacterial surface, enabling bacterial adhesion to mammalian cells. Inhibitory studies of this enzyme have gained prominent interest as a new pathway for drug development since blocking this enzyme's ability to …

Lithium Tetraborate As A Neutron Scintillation Detector: A Review, Elena Echeverria, John W. Mcclory, Lauren Samson, Katherine Shene, Juan A. Colon Santana, Yaroslav V. Burak, Volodymyr T. Adamiv, Ihor M. Teslyuk, Lu Wang, Wai-Ning Mei, Kyle A. Nelson, Douglas S. Mcgregor, Peter A. Dowben, Carolina C. Ilie, James C. Petrosky, Archit Dhingra

Faculty Publications

The electronic structure and translucent nature of lithium tetraborate (Li₂B₄O₇) render it promising as a scintillator medium for neutron detection applications. The inherently large neutron capture cross-section due to ¹⁰B and ⁶Li isotopes and the ease with which Li₂B₄O₇ can be enriched with these isotopes, combined with the facile inclusion of rare earth dopants (occupying the Li⁺ sites), are expected to improve the luminescent properties, as well as the neutron detection efficiency, of Li₂B₄O₇. The electronic structure of both doped …