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Articles 73501 - 73530 of 73532
Full-Text Articles in Entire DC Network
Identifying Core Components Of A Radiotherapy Comfort Intervention Package Using Nominal Group Technique Radiography, S. Goldsworthy, J.M. Latour, S. Palmer, H. Mcnair, M. Cramp
Identifying Core Components Of A Radiotherapy Comfort Intervention Package Using Nominal Group Technique Radiography, S. Goldsworthy, J.M. Latour, S. Palmer, H. Mcnair, M. Cramp
School of Nursing and Midwifery
Introduction A comfortable treatment position in radiotherapy may promote patient stability and improve outcomes such as accuracy. The aim of this study was to identify, prioritise and determine the feasibility of delivery of intervention components as part of a radiotherapy comfort intervention package. Methods Prior research, consisting of a systematic review and qualitative interviews with patient and therapeutic radiographers, was triangulated and 15 intervention components developed. An online nominal group technique consensus meeting with 7 patients who received radiotherapy exceeding 10 min for one of three anatomical cancer sites and 3 therapeutic radiographers (TRs) participated. Four activities were undertaken: 1) …
Student-Led Health Promotion Toolkit: A Practice Development Project, R Reynolds, S Neill
Student-Led Health Promotion Toolkit: A Practice Development Project, R Reynolds, S Neill
School of Nursing and Midwifery
Student nurses are uniquely placed to contribute to health promotion during their undergraduate programmes. The aim of this practice development project was to co-develop a toolkit to facilitate student nurse led health promotion practice. The project used an emancipatory methodology to explore health promotion practice opportunities for one university cohort of student nurses in partnership with the local practice area. A person-centred framework was used to engage with students and nurses to benchmark current student practice, scope for student-led activity and develop a shared vision for the toolkit resources. The student questionnaire revealed greater confidence in health promotion knowledge than …
End-Of-Life Care In The Last Three Months Before Death In Older Patients With Cancer In Belgium: A Large Retrospective Cohort Study Using Data Linkage, Victoria Depoorter, Katrijn Vanschoenbeek, Lore Decoster, Geert Silversmit, Philip R. Debruyne, Inge De Groof, Dominique Bron, Frank Cornélis, Sylvie Luce, Christian Focan, Vincent Verschaeve, Gwenaëlle Debugne, Christine Langenaeken, Heidi Van Den Bulck, Jean Charles Goeminne, Wesley Teurfs, Guy Jerusalem, Dirk Schrijvers, Bénédicte Petit, Marika Rasschaert, Jean Philippe Praet, Katherine Vandenborre, Harlinde De Schutter, Koen Milisen, Johan Flamaing, Cindy Kenis, Freija Verdoodt, Hans Wildiers
End-Of-Life Care In The Last Three Months Before Death In Older Patients With Cancer In Belgium: A Large Retrospective Cohort Study Using Data Linkage, Victoria Depoorter, Katrijn Vanschoenbeek, Lore Decoster, Geert Silversmit, Philip R. Debruyne, Inge De Groof, Dominique Bron, Frank Cornélis, Sylvie Luce, Christian Focan, Vincent Verschaeve, Gwenaëlle Debugne, Christine Langenaeken, Heidi Van Den Bulck, Jean Charles Goeminne, Wesley Teurfs, Guy Jerusalem, Dirk Schrijvers, Bénédicte Petit, Marika Rasschaert, Jean Philippe Praet, Katherine Vandenborre, Harlinde De Schutter, Koen Milisen, Johan Flamaing, Cindy Kenis, Freija Verdoodt, Hans Wildiers
School of Nursing and Midwifery
This study aims to describe end-of-life (EOL) care in older patients with cancer and investigate the association between geriatric assessment (GA) results and specialized palliative care (SPC) use. Older patients with a new cancer diagnosis (2009–2015) originally included in a previous multicentric study were selected if they died before the end of follow-up (2019). At the time of cancer diagnosis, patients underwent geriatric screening with Geriatric 8 (G8) followed by GA in case of a G8 score ≤14/17. These data were linked to the cancer registry and healthcare reimbursement data for follow-up. EOL care was assessed in the last three …
How Does Religious Faith Impact Positive Youth Outcomes, Michael A. Goodman, W. Justin Dyer
How Does Religious Faith Impact Positive Youth Outcomes, Michael A. Goodman, W. Justin Dyer
Faculty Publications
This study investigates the protective aspects of religiosity in young adolescents and explores the potential processes involved. Specifically, we examine the influence of three measures of religiosity—religious salience, intrinsic religiosity, and daily religious experiences—on delinquency and anxiety. The study sample consists of 636 families located in the state of Utah. Additionally, we explore how positive youth development (PYD) constructs may mediate the relationship between religiosity and adolescent outcomes. The findings indicate that religious salience and daily religious experiences are directly and indirectly associated with lower levels of delinquency and anxiety. Furthermore, two PYD constructs—character and connectivity—serve as mediators between religious …
Family Home Evening As A Model For Promoting Family Health, Tommy M. Phillips, Jennifer R. Smith, Alice C. Long, Brandan E. Wheeler, Loren D. Marks, Michael Goodman, Trevan Hatch, Sterling K. Wall
Family Home Evening As A Model For Promoting Family Health, Tommy M. Phillips, Jennifer R. Smith, Alice C. Long, Brandan E. Wheeler, Loren D. Marks, Michael Goodman, Trevan Hatch, Sterling K. Wall
Faculty Publications
One hundred thirty-seven married members of the Church of Jesus Christ of Latter-day Saints with children participated in a study of Family Home Evening and its relation to family well-being. Results support previous research suggesting that regular family-level rituals and sacred practices benefit families, marriages, and parent-child relationships. While this study‟s results cannot demonstrate any sort of causal link, they do provide very strong correlational evidence in support of the power and value of regular family-level routines, rituals, and sacred practices, as seen in LDS observance of FHE. Implications for the full universe of families are discussed.
Reframing Commitment In Authentic Leadership: Untangling Relationship–Outcome Processes, Andrei A. Lux, Steven L. Grover, Stephen T. T. Teo
Reframing Commitment In Authentic Leadership: Untangling Relationship–Outcome Processes, Andrei A. Lux, Steven L. Grover, Stephen T. T. Teo
Research outputs 2014 to 2021
Affective organizational commitment is theorized and empirically tested as a key mediator between authentic leadership and desirable employee outcomes. The results of a two-wave survey of 830 business people in Australia support a serial mediation model of authentic leadership efficacy. Followers' perceptions of authentic leadership behavior influence their personal identification and affect-based trust in the leader, which in turn are mediated by affective organizational commitment to positively influence their work engagement and job satisfaction. These findings reinforce previous work that positions personal identification and affect-based trust as the two primary mediating mechanisms of authentic leadership. This paper extends prior research …
Key Success Factors For “Real World” Projects: A Principal- Agency Theory Perspective, Degan Kettles, Dan Mazzola, Mary Sumner, Mahesh Raisinghani
Key Success Factors For “Real World” Projects: A Principal- Agency Theory Perspective, Degan Kettles, Dan Mazzola, Mary Sumner, Mahesh Raisinghani
Faculty Publications
“Real world” projects are an important component of MIS academic programs. These “real world” projects provide students with problem-based learning opportunities which enable them to address “real world” problems and opportunities. The purpose of this research-in-progress is to determine the key success factors for “real world” projects. The concept of Principal-Agency Theory provides a theoretical lens for understanding these success factors from the viewpoint of students, faculty, and industry sponsors. The SIM academic research team will collect data from project teams across ten universities and for over 250 projects. Having multiple perspectives will contribute to an understanding of how to …
Charting A Course To The Top: Insights From The Fortune 500 Cios And How They Differ From Other C-Suite Executives, Benjamin Richardson, Degan Kettles, Daniel Mazzola
Charting A Course To The Top: Insights From The Fortune 500 Cios And How They Differ From Other C-Suite Executives, Benjamin Richardson, Degan Kettles, Daniel Mazzola
Faculty Publications
No abstract provided.
Pattern-Based Target Selection For Treatment Of Irregular Past Tense: A Single-Case Experimental Design For Children With Developmental Language Disorder, Kirsten M. Russell, Amy Wilder, Julie L. Wambaugh
Pattern-Based Target Selection For Treatment Of Irregular Past Tense: A Single-Case Experimental Design For Children With Developmental Language Disorder, Kirsten M. Russell, Amy Wilder, Julie L. Wambaugh
Faculty Publications
Purpose: Many children with developmental language disorder (DLD) demonstrate
difficulty inflecting irregular past tense verbs. We evaluated using phonological-
based patterns (i.e., schemas) to select targets for treatment of irregular verb inflection for children with DLD. We hypothesized this approach would result in acquisition of treated verbs, generalization to untreated verbs within the same phonological schema, and increased use of correct irregular verbs in naturalistic contexts. Method: Treatment was provided to three 7-year-old participants with DLD in the context of multiple baseline designs across behaviors and participants. Phonological schemas included vowel change, final alveolar, and dual change irregular verbs. Treatment …
Boomer Peak Or Gen X Cliff? From Svs To Lbms In Georgia English, Margaret E. L. Renwick, Joseph A. Stanley, Jon Forrest, Lelia Glass
Boomer Peak Or Gen X Cliff? From Svs To Lbms In Georgia English, Margaret E. L. Renwick, Joseph A. Stanley, Jon Forrest, Lelia Glass
Faculty Publications
The late twentieth century in the United States marks the decline of regional vowel systems like the Northern Cities Shift and the Southern Vowel Shift, replaced by supralocal systems like the Low-Back-Merger Shift.We chart such change in acoustic data from seven generations of White speakers (n = 135) in the Southeastern state of Georgia. We analyze front vowels affected by both the SVS and LBMS (DRESS, TRAP), plus PRICE and FACE, known respectively to monophthongize and centralize in the SVS, and LBMS-implicated LOT/ THOUGHT. The SVS is most advanced among Georgians born in the mid-twentieth century, particularly in FACE-centralization. In …
Sample Size Matters In Calculating Pillai Scores, Joseph A. Stanley, Betsy Sneller
Sample Size Matters In Calculating Pillai Scores, Joseph A. Stanley, Betsy Sneller
Faculty Publications
Since their introduction to sociolinguistics by Hay, Warren, and Drager [(2006). J. Phon. (Modell. Sociophon. Var.) 34(4), 458–484], Pillai scores have become a standard metric for quantifying vowel overlap. However, there is no established threshold value for determining whether two vowels are merged, leading to conflicting ad hoc measures. Furthermore, as a parametric measure, Pillai scores are sensitive to sample size. In this paper, we use generated data from a simulated pair of underlyingly merged vowels to demonstrate (1) larger sample sizes yield reliably more accurate Pillai scores, (2) unequal group sizes across the two vowel classes are irrelevant in …
Sociophonetics And Dialectology, Dominic Watt, Margaret E. L. Renwick, Joseph A. Stanley
Sociophonetics And Dialectology, Dominic Watt, Margaret E. L. Renwick, Joseph A. Stanley
Faculty Publications
In this chapter we explore how the investigation of phonetic detail in speech seen through a sociolinguistic lens can inform and enhance our understanding of dialectal variation in languages. We begin by examining how sociophonetics can be considered an offshoot of dialectology, later to mature into a free- standing discipline during the late twentieth century. We next discuss the reconvergence of sociophonetics and dialectology as it became clearer that the two approaches to the study of language variation are, in combination, greater than the sum of their parts, even if their agendas may place different emphases on what should be …
The Missionary Voice: Perceptions Of An Emerging Register, Josh Stevenson, Joseph A. Stanley, Wendy Baker-Smemoe
The Missionary Voice: Perceptions Of An Emerging Register, Josh Stevenson, Joseph A. Stanley, Wendy Baker-Smemoe
Faculty Publications
Today’s presentation is on a particular way of speaking among certain members of the Church of Jesus Christ of Latter-day Saints. Specifically, today I’ll be telling you about Latter-day Saint missionaries, who you may encountered before. Let’s set aside any preconceived notions you may have about missionaries or their faith and explore what appears to be an emerging missionary-based register.
In essence, missionaries are Latter-day Saint volunteers who dedicate 18 months to two years to tell others about their faith. They’re assigned around the world and often have to learn a new language, are typically college-aged, and adhere to strict …
Perceptions Of “Southern” Utah English, Chad Huckvale, Joseph A. Stanley
Perceptions Of “Southern” Utah English, Chad Huckvale, Joseph A. Stanley
Faculty Publications
Utahns generally have negative perceptions of their own speech (Savage 2014, Eddington & Brown 2021, Stanley 2023).
Utahns are aware of certain features in their speech, namely pronunciation of “mountain” (Eddington & Savage 2012; Stanley & Vandiernet 2018; Eddington & Brown 2021, Stanley 2023).
Previous dialectology research (Lillie 1998; Eddington 2022; Stanley 2022) indicates that speech in some areas of Utah are described as “Southern”; this is generally found to differentiate urban vs. rural regions.
Surzhyk: Attitudes & Usage Among Ukrainian People, Kateryna Kravchenko, Joseph A. Stanley
Surzhyk: Attitudes & Usage Among Ukrainian People, Kateryna Kravchenko, Joseph A. Stanley
Faculty Publications
What is Surzhyk?
- refers to a range of macaronic (mixed) sociolects of Ukrainian and Russian languages
- originally meant mixing of two different types of flour (wheat and rye), which is considered a lower grade flour
- there is no unifying set of characteristics
- the term is used for norm-breaking, non-obedience to or non-awareness of the rules of the Ukrainian and Russian standard languages
- it is not Russian-accented Ukrainian
Enriching Our Understanding Of Language Change With Vowel Formant Trajectories, Joseph A. Stanley
Enriching Our Understanding Of Language Change With Vowel Formant Trajectories, Joseph A. Stanley
Faculty Publications
American English vowels are variable in pronunciation
- ban vs. bat, too vs. boo
- feel vs. fill, [bæt] vs. [bæ̞̙ t]
We can categorize these differences:
Shifts:
- I pronounce /u/ fronter than my grandparents do.
- My students pronounce /æ/ as lower and more centralized than I do.
Mergers:
- For me, cot and caught are distinct; for 95% of my students, they’re homophones
- In Utah, feel and fill are often pronounced the same
Language change happens as some variants spread to more and more people.
Qualitative Oral-Presentation Feedback: Comparisons From Business Professionals, Instructors, And Student Peers, Matt Baker, William H. Baker
Qualitative Oral-Presentation Feedback: Comparisons From Business Professionals, Instructors, And Student Peers, Matt Baker, William H. Baker
Faculty Publications
Previous studies compare quantitative feedback ratings of student peers and instructors, but new presentation-feedback technologies enable qualitative-feedback comparison. This study extends previous research by comparing qualitative feedback and business professionals’ feedback. Compared to the professionals, the instructors provided similar feedback types and sentiment; students, however, de-emphasized message delivery and made fewer suggestions for improvement. The results suggest that students may need additional practice in critiquing message delivery and in suggesting needed improvements in their peers’ oral presentations. The study also provides a methodology using the new technologies for instructors to calibrate their own and their students’ feedback with professionals’ feedback.
Multiple-Choice Reading Behaviors Of Esl Students: An Eye-Tracking Study, Juan Escalante, Grant Eckstein, Troy L. Cox, Steven Luke
Multiple-Choice Reading Behaviors Of Esl Students: An Eye-Tracking Study, Juan Escalante, Grant Eckstein, Troy L. Cox, Steven Luke
Faculty Publications
Only recently has eye-tracking been used to investigate test-taker reading behavior, and results have been primarily used to confirm a range of cognitive tasks elicited by test items. This study explores test taker reading behavior for its own sake by describing how ESL readers of different proficiency levels behaviorally view multiple-choice passages and test items at different difficulty levels. Data were gathered from 51 students at three proficiency levels attending a university-sponsored intensive English program (IEP). Participants read eight validated reading comprehension items at varying difficulty levels while their eye movements were recorded on the passage, multiple-choice stem, correct answer, …
Does Text Entry Method Make A Difference On Chinese Writing Test Scores?, Dana Scott Bourgerie, Troy L. Cox, Steven L. Riep
Does Text Entry Method Make A Difference On Chinese Writing Test Scores?, Dana Scott Bourgerie, Troy L. Cox, Steven L. Riep
Faculty Publications
Should the writing construct be assessed through handwriting or keyboarding? As the only major language entirely without a syllabary or alphabet, the Chinese writing system is unique among modern languages, thus the question of writing proficiency is complicated by character recall. Most of the testing research comparing text entry methods has been conducted in English and has found that keyboarding and handwriting can be used interchangeably. This paper reports the outcome of a study comparing the results of handwritten and typed versions of the Chinese ACTFL Writing Proficiency Test (WPT). L2 Chinese students (n=25) with Intermediate to Superior speaking skills …
Corrosion Behavior And Mechanism Of Laser Powder Bed Fusion Produced Cocrw In An Acidic Nacl Solution, P. Qin, L. Y. Chen, Y. J. Liu, C. H. Zhao, Hongqi Sun, Laichang Zhang
Corrosion Behavior And Mechanism Of Laser Powder Bed Fusion Produced Cocrw In An Acidic Nacl Solution, P. Qin, L. Y. Chen, Y. J. Liu, C. H. Zhao, Hongqi Sun, Laichang Zhang
Research outputs 2022 to 2026
The corrosion behavior and mechanism of the laser powder bed fusion (L-PBF) produced CoCrW were investigated in 0.9 wt% NaCl solution with a pH of 2. The corrosion resistance of the alloy increases after 28 days of immersion because of the formed oxide film, which results in the increased corrosion potential and the decreased passivation current density on the potentiodynamic polarization test. The corrosion mechanism of the L-PBF-produced CoCrW could be explained by the melt pool formed from the laser melting process, that the melt pools were “shrinking” by the formation and dissolution of the oxide film.
Burden And Preference-Based Quality Of Life Associated With Bullying In Children, Long K. D. Le, Mary L. Chatterton, Ronald M. Rapee, Sally Fitzpatrick, Kay Bussey, Jennie Hudson, Caroline Hunt, Donna Cross, Anne Magnus, Cathrine Mihalopoulos
Burden And Preference-Based Quality Of Life Associated With Bullying In Children, Long K. D. Le, Mary L. Chatterton, Ronald M. Rapee, Sally Fitzpatrick, Kay Bussey, Jennie Hudson, Caroline Hunt, Donna Cross, Anne Magnus, Cathrine Mihalopoulos
Research outputs 2014 to 2021
The objectives of this study are to assess the association between childhood bullying and preference-based health-related quality of life (QoL) in Australian school children and their parents and estimate quality-adjusted life years (QALYs) associated with bullying chronicity. Children aged 8–10 years completed the child health utilities (CHU-9D), while parents completed the Australian quality of life (AQoL-8D). Children were grouped into four categories of bullying involvement (no bullying, victim, perpetrator, or both perpetrator and victim) based on the Revised Olweus Bully/Victim Questionnaire. Parental data were compared across two bullying involvement groups (bullying vs. no bullying). QALYs were calculated for children over …
‘We And Our Stories’: Constructing Food Experiences In A Unesco Gastronomy City, Eerang Park, Kaewta Muangasame, Sangkyun Kim
‘We And Our Stories’: Constructing Food Experiences In A Unesco Gastronomy City, Eerang Park, Kaewta Muangasame, Sangkyun Kim
Research outputs 2014 to 2021
The experiential elements of food tourism can be transformed into meaningful experiences of local food heritage and identity in the context of a UNESCO Creative City of Gastronomy. From a local stakeholder perspective, six key drivers at three phases of the food experience are identified, and each driver involves several local elements that are coordinated and staged in various modes to create and develop four sequential food experiences. The pre-travel stage should focus on enhancing potential tourist’s awareness of the UNESCO designation. The on-site food experience is found to be twofold: exposure to the local food environment and the actual …
Professional Teaching Standards And Inclusion In Teacher Education: Insights From A Hearing-Impaired Health And Physical Education Pre-Service Teacher’S Professional Experience, Donna Barwood, John O'Rourke, Dawn Penney, Andrew Jones, Jordan Thomas
Professional Teaching Standards And Inclusion In Teacher Education: Insights From A Hearing-Impaired Health And Physical Education Pre-Service Teacher’S Professional Experience, Donna Barwood, John O'Rourke, Dawn Penney, Andrew Jones, Jordan Thomas
Research outputs 2014 to 2021
Initial Teacher Education (ITE) is a critical arena for advancing inclusion in Health and Physical Education (HPE). This paper reports research that is engaging with the diversity of the HPE profession and practitioners. It centres on a unique case study that critically explored the school-based professional experience of an Australian secondary HPE Pre-service Teacher (PsT) who has a hearing impairment. Specifically, to enable PST success in HPE professional experiences as defined by the professional standards for teachers in Australia and to which, PSTs’ must evidence to graduate and attain teacher registration. Drawing on documentary and interview data the paper focuses …
A Behaviour Sequence Analysis Of Goal Generation Processes In A Psychosis Rehabilitation Sample, Esmira Ropaj, David A. Keatley, Joanne M. Dickson, Corinna J. Milroyd, Peter J. Taylor
A Behaviour Sequence Analysis Of Goal Generation Processes In A Psychosis Rehabilitation Sample, Esmira Ropaj, David A. Keatley, Joanne M. Dickson, Corinna J. Milroyd, Peter J. Taylor
Research outputs 2014 to 2021
Background:
It is suggested that goals are hierarchically organised, with goals at the highest level representing fundamental values and motivations. These abstract goals are said to have a series of sub-goals which represent a means of reaching higher-level goals. While a number of studies have explored goals in the context of psychosis, little is known about idiographic goal generation processes in those experiencing psychosis.
Methods:
Using a Behaviour Sequence Analysis approach, the aim of the current study was to assess the feasibility of the goal task for use with individuals experiencing psychosis. A total of 73 adults receiving care from …
Incidence And Mortality Of Uveal Melanoma In Australia (1982–2014), Aaron B. Beasley, David B. Preen, Samuel Mclenachan, Elin S. Gray, Fred K. Chen
Incidence And Mortality Of Uveal Melanoma In Australia (1982–2014), Aaron B. Beasley, David B. Preen, Samuel Mclenachan, Elin S. Gray, Fred K. Chen
Research outputs 2014 to 2021
Aims:
We aimed to estimate the incidence and mortality of uveal melanoma (UM) in Australia from 1982 to 2014.
Methods:
Deidentified unit data for all cases of ocular melanoma were extracted from the Australian Cancer Database from 1 January 1982 to 31 December 2014. UM cases were extracted and trends in incidence and disease-specific mortality were calculated. Incidence rates were age-standardised against the 2001 Australian Standard Population. Mortality was assessed using Cox regression.
Results:
From 1982 to 2014, there were 5087 cases of ocular melanoma in Australia, of which 4617 were classified as UM. The average age-standardised incidence rate of …
Walking Off-Trail In National Parks: Monkey See Monkey Do, Edmund Goh
Walking Off-Trail In National Parks: Monkey See Monkey Do, Edmund Goh
Research outputs 2014 to 2021
This study extended the theory of planned behavior (TPB) to embrace the pro-environmental construct in predicting visitor off-trail behavioral intentions at national parks. Quantitative questionnaire items were developed through an elicitation study and empirically tested among 325 respondents. Empirical results revealed overall predictive variance of 21.7 percent (R2) in predicting visitor off-trail intentions. Behavioral beliefs predicted most of behavioral intentions followed by normative beliefs. The contribution of control beliefs and pro-environmental values had the weakest predictive power. Among the behavioral beliefs, visitors had the strongest belief that walking off the trails would lead to a shorter route. Friends …
Reporting And Mapping Research Evidence On Perceptions Of Clinical Hypnosis Among The General Population And Patients Receiving Health Care Including Cancer Care: A Scoping Review, Malwina Szmaglinska, Deborah Kirk, Lesley Andrew
Reporting And Mapping Research Evidence On Perceptions Of Clinical Hypnosis Among The General Population And Patients Receiving Health Care Including Cancer Care: A Scoping Review, Malwina Szmaglinska, Deborah Kirk, Lesley Andrew
Research outputs 2022 to 2026
Despite empirical evidence supporting clinical hypnosis for numerous conditions, its utilization in healthcare is limited due to skepticism and misconceptions. This review identifies and maps research on clinical hypnosis perceptions among the general population, healthcare patients, and more specifically patients with cancer. A systematic search following JBI PRISMA ScR guidelines was conducted in EBSCOhost, ProQuest, PubMed, and PMC, resulting in 18 peer-reviewed, English language articles (2000–2023). Most studies employed quantitative methods, which were complemented by some qualitative and one mixed-methods approach. The results found attitudes toward hypnotherapy, especially when administered by licensed professionals, are consistently positive; however, awareness of hypnosis …
Elafibranor Modulates Ileal Macrophage Polarization To Restore Intestinal Integrity In Nash: Potential Crosstalk Between Ileal Il-10/Stat3 And Hepatic Tlr4/Nf-Κb Axes, Andrew Hakeem, Mohamed M. Kamal, Rasha A. Radwan, Basma A. Abdelrahman, Olfat A. Hammam, Mohey M. Elmazar, Aiman S. El-Khatib, Yasmeen M. Attia
Elafibranor Modulates Ileal Macrophage Polarization To Restore Intestinal Integrity In Nash: Potential Crosstalk Between Ileal Il-10/Stat3 And Hepatic Tlr4/Nf-Κb Axes, Andrew Hakeem, Mohamed M. Kamal, Rasha A. Radwan, Basma A. Abdelrahman, Olfat A. Hammam, Mohey M. Elmazar, Aiman S. El-Khatib, Yasmeen M. Attia
Pharmacy
Experimental and clinical evidence implicate disrupted gut barrier integrity in provoking innate immune responses, specifically macrophages, towards the progression of non-alcoholic steatohepatitis (NASH). Peroxisome proliferator-activated receptors (PPARs), a subset of the nuclear receptor superfamily, act to fine-tune several metabolic and inflammatory processes implicated in NASH. As such, the current study was carried out to decipher the potential role of dual PPAR α/δ activation using elafibranor (ELA) on ileal macrophage polarization (MP) and its likely impact on the liver in a NASH setting. To achieve this aim, an in vitro NASH model using fat-laden HepG2 cells was first used to validate …
Africa Guidelines For Hepatocellular Carcinoma Buildup Process, Ghassan Abou-Alfa, Mary Afihene, Marinela Capanu, Joanne Chou, Akwi Asombang, Olusegun Alatise, Adda Bounedjar, Lina Cunha, Hailemichael Mekonnen, Papa Diop, Reda Elwakil, Mahamat Ali, Ntokozo Ndlovu, Jerry Ndumbalo, Precious Makondi, Christian Tzeuton, Tiago Castria, Adwoa Afrakoma Agyei-Nkansah, Fiyinfolu Balogun, Alain Bougouma, Blaise Ibara, Eduard Jonas, Stephen Kimani, Peter Kingham, Reshad Kurrimbukus, Nazik Hammad, Mona Fouad, Noha S. El Baghdady, Eloumou Fiacre, Vikash Sewram, C. Wendy Spearman, Ju Yang, Lewis Roberts, Ashraf Abdelaziz
Africa Guidelines For Hepatocellular Carcinoma Buildup Process, Ghassan Abou-Alfa, Mary Afihene, Marinela Capanu, Joanne Chou, Akwi Asombang, Olusegun Alatise, Adda Bounedjar, Lina Cunha, Hailemichael Mekonnen, Papa Diop, Reda Elwakil, Mahamat Ali, Ntokozo Ndlovu, Jerry Ndumbalo, Precious Makondi, Christian Tzeuton, Tiago Castria, Adwoa Afrakoma Agyei-Nkansah, Fiyinfolu Balogun, Alain Bougouma, Blaise Ibara, Eduard Jonas, Stephen Kimani, Peter Kingham, Reshad Kurrimbukus, Nazik Hammad, Mona Fouad, Noha S. El Baghdady, Eloumou Fiacre, Vikash Sewram, C. Wendy Spearman, Ju Yang, Lewis Roberts, Ashraf Abdelaziz
Pharmacy
Abstract
Purpose
Hepatocellular carcinoma (HCC), the fourth most common cancer in Africa, has a dismal overall survival of only 3 months like in sub-Saharan Africa. This is affected by the low gross domestic product and human development index, absence of coherent guidelines, and other factors.
Methods
An open forum for HCC-experienced health care workers from Africa and the rest of the world was held in October 2021. Participants completed a survey to help assess the real-life access to screening, diagnoses, and treatment in the North and Southern Africa (NS), East and West Africa (EW), Central Africa (C), and the rest …
Primary Specialisations In Australia: Graduates’ Perceptions Of Outcome And Impact, Susan Main, Matt Byrne, Joseph Scott, Kevin Sullivan, Annamaria Paolino, Eileen Slater, Jason Boron
Primary Specialisations In Australia: Graduates’ Perceptions Of Outcome And Impact, Susan Main, Matt Byrne, Joseph Scott, Kevin Sullivan, Annamaria Paolino, Eileen Slater, Jason Boron
Research outputs 2014 to 2021
In 2014, the Australian Government established the Teacher Education Ministerial Advisory Group (TEMAG) to advise on how teacher education programmes could ensure new teachers were adequately prepared for the classroom. Following this, the Australian Government endorsed a key recommendation of the TEMAG Action Now: Classroom Ready Teachers report, the inclusion of specialisations in primary Initial Teacher Education (ITE). This research was conducted at an Australian public university that, in 2016, had embedded specialisations in a revised primary teacher programme structure and was one of the first ITE institutions in Australia to graduate primary teachers with a specialisation. Using a mixed-methods …