Digital Commons Network^™

Entrainment And Horizontal Atmospheric Transport Of Microplastics From Soil, Sajjad Abbasi, Mahrooz Rezaei, Monireh Mina, Abdolmajid Sameni, Patryk Oleszczuk, Andrew Turner, Coen Ritsema

School of Geography, Earth and Environmental Sciences

Soils are an important source of microplastics (MPs) to the atmosphere but the fluxes and mechanisms involved in MPs entrainment are not well understood. In the present study, a series of horizontally aligned sediment traps have been deployed at different heights within 1 m above the ground for a two-month period at various locations in an arid region (Sarakhs, Iran). MPs were isolated from sediments and were quantified and characterised according to size, colour, shape and polymer composition by established techniques. Most MPs were <250 μm in length, fibres were the most important shape, black and blue-green were the dominant colours, and polymer abundance decreased in the order polyethylene > nylon > polypropylene > polystyrene > polyethylene terephthalate. The distributions of sediment mass (range <0.01–9 g) and number of MPs (range = 0 to 21) were heterogeneous, both between sites and at the different heights sampled, and yielded median, vertically-averaged horizontal fluxes for the region of about 450 g m−2 d−1 and 2600 MP m−2 d−1, respectively. However, when data were pooled, the number of MPs normalised to sediment mass exhibited a significant inverse relationship with sediment mass, an effect attributed to the presence of ambient suspended MPs and sediment that are diluted by the suspension of soil and deposited MPs at higher wind speeds. The mechanisms of MP saltation and entrainment were not ascertained but a theoretical framework for threshold shear velocity based on regularly-shaped particles and density considerations is presented. Further experimental work is required to verify this framework, and in particular for fibrous MPs with different aerodynamic properties to soil particles.

Impacts Of Polyethylene Microplastics On The Microalga, Spirulina (Arthrospira Platensis), Sajjad Abbasi, Sahar Amiranipour, Javad Karimi, Sasan Mohsenzadeh, Andrew Turner

School of Geography, Earth and Environmental Sciences

Microalgae play a critical role in the food web and biogeochemical cycling and produce compounds that are commercially exploited. However, their reactions and responses to microplastic contamination are not well understood. In this study, the widely distributed and commercially important cyanobacterium, Spirulina (Arthrospira platensis), was exposed to different concentrations (1–100 mg L−1) of low-density polyethylene microplastics (<5 μm) over a 20-d period. Various end-points were combined with different microscopic techniques in order to examine physiological and biochemical effects and interactions between the plastic and microalga. Growth rate and photosynthetic activity decreased with increasing microplastic concentration, and a maximum inhibition ratio of about 9% was calculated from optical density measurements. Plastic concentrations above 10 mg L−1 resulted in oxidative stress and the intracellular production of proline. Fragmentation and swelling of trichomes and attachment of microplastics was observed in the exposures, and microplastics appeared to adhere or aggregate around fragmented or fragmenting regions. The latter effect may indicate trichome weakening by microplastics or their concentration around cytosolic debris; nevertheless, it provides a potential mechanism for internalisation of small particles. Although unrealistically high concentrations of well-defined microplastics have been employed, relatively small disruptions at the population level incurred by lower concentrations could have more serious implications for ecosystem services and functioning.

Physical And Biogeochemical Controls On Seasonal Iron, Manganese, And Cobalt Distributions In Northeast Atlantic Shelf Seas, Xue Gang Chen, Dagmara Rusiecka, Martha Gledhill, Angela Milne, Amber L. Annett, Aaron Joseph Beck, Antony J. Birchill, Maeve C. Lohan, Simon Ussher, Eric P. Achterberg

School of Geography, Earth and Environmental Sciences

No abstract provided.

Accumulation Of Polystyrene Nanoplastics And Triclosan By A Model Tooth-Carp Fish, Aphaniops Hormuzensis (Teleostei: Aphaniidae), Maryam Saemi-Komsari, Reza Pashaei, Sajjad Abbasi, Hamid Reza Esmaeili, Reda Dzingelevičienė, Hadavand B Shirkavand, Kalako M Pasalari, Malgorzata Szultka-Mlynska, Renata Gadzała-Kopciuch, Boguslaw Buszewski, Andrew Turner

School of Geography, Earth and Environmental Sciences

The presence and effects of nanoplastics (NPs; <1 μm) in the aquatic environment are a growing concern. In this study, a model tooth-carp fish, Aphaniops hormuzensis, has been exposed to different concentrations of fluorescent polystyrene nanoplastics (PS-NP) in its diet (up to 5 mg kg−1) over periods of 28 d and the particle accumulation in different tissues determined. Accumulation was observed in both digestive and non-digestive organs, with concentrations greater in the gut, liver and gill (up to 400 μg kg−1 dw) than in the skin and muscle (<180 μg kg−1 dw), but no dependency on exposure time or dose was evident. The presence of the organic contaminant, triclosan (TCS), in the diet and at concentrations up to 0.5 μg kg−1 did not affect PS-NP uptake by A. hormuzensis, while TCS accumulation in the whole body increased with time (up to 10 μg kg−1) and, likewise, appeared to be unaffected by the presence of PS-NPs. These observations suggest that the two contaminants do not interact with each other or that any interactions have no impact on accumulation. The results of this study add to the growing body of evidence that NPs can be translocated by aquatic organisms after ingestion, and reveal that, for the species and conditions employed, nanoplastics are accumulated more readily than a widely used organic chemical.

Occurrence And Characteristics Of Fibreglass-Reinforced Plastics And Microplastics On A Beach Impacted By Abandoned Fishing Boats: A Case Study From Chellanam, India, N. Manju Lekshmi, Sreejith S. Kumar, P. Muhamed Ashraf, S. P. Nehala, Leela Edwin, Andrew Turner

School of Geography, Earth and Environmental Sciences

Plastics and microplastics have been quantified and characterised at disposal sites of abandoned fishing boats and along the high-water line (HWL) of a fish landing centre in Chellanam, India. Fibreglass-reinforced plastic (FRP) made a greater contribution to the plastic pool at the disposal sites (~ 4.5 n m−2 and 18 g m−2) than the HWL (~ 0.25 n m−2 and < 1 g m−2) and was an abundant component of the microplastic pool at the former. Infrared analysis of micro-sized FRPs revealed various resins (e.g., alkyd, polyester, epoxy), while X-ray fluorescence analysis of the painted surfaces of meso-sized FRPs returned variable concentrations of copper and lead. Concentrations of Pb were high enough to contaminate sand up to ~400 mg kg−1. The relatively high density of FRP and its association with glass fibres and metal-bearing paints results in particles with potentially very different fates and toxicities to more “conventional” (non-composite) thermoplastics.

Personality And Parental Care In The Corkwing Wrasse (Symphodus Melops), Benjamin Ellis

School of Biological and Marine Sciences Theses

Parental care in many species is a repeatable aspect of the behavioural phenotype, in some cases covarying with other behavioural traits within wider behavioural syndromes. It is well understood that in several freshwater fishes, recreational and commercial fisheries often (directly or indirectly) impact traits concerning parental care adversely, in some cases through selection on covarying behavioural traits. In contrast, studies on commercially fished marine species that exhibit parental care are scarce. The corkwing wrasse (Symphodus melops) is a marine fish with complex reproductive behaviour, with parental males exhibiting nest building and parental care behaviours. This species is also subject to …

Nurses’ Perceptions Of The Skills, Knowledge And Attributes Required To Optimise Scope Of Practice And Improve Access To Care For People Experiencing Homelessness In Australia: A Cross-Sectional Study, Jane Currie, Lucy Mcwilliams, Martha Paisi, Jill Shawe, Anna Thornton, Matthew Larkin, Joanne Taylor, Sandy Middleton

School of Nursing and Midwifery

Background People experiencing homelessness are less likely to access healthcare, particularly primary and preventive care. Nurses are well placed to improve access to healthcare for this vulnerable population. Aim To explore nurses’ perceptions of the skills, knowledge and attributes required to optimise scope of practice and improve access to healthcare for people experiencing homelessness, to underpin an education framework. Design A cross-sectional national survey of nurses in Australia. Methods Part of a larger study, a 222-item electronic survey was disseminated via social media and nursing colleges and associations. Participants rated the level of priority of specific skills knowledge and attributes …

The Nutritional Online Survey For Pregnancy Induced Sickness & Hyperemesis (Nourish) Study: Results From The First Trimester, Kate Maslin, Caitlin Dean, Jill Shawe

School of Nursing and Midwifery

Background:Hyperemesis gravidarum (HG) is severe pregnancy sickness,often leading to dehydration, weight loss and electrolyte disturbances. Little isknown about nutritional intake and its consequences in those affected. Theaim of this study was to explore thefirst trimester nutritional intake andclinical characteristics in those with severe sickness.Method:Recruitment was via the social media accounts of national pregnancycharities. The eligibility criteria were as follows: between 6 and 11 weekspregnant, age≥18 years and residing in the UK. Participants completed a self‐report online questionnaire including the Pregnancy Unique Quantification ofEmesis 24 (PUQE24) score and a 3‐day online diet diary. Groups werecompared by PUQE24 categories. Nutritional intakes were …

Variability In Feeding Habitats Of Red Deer Sensu Lato In Eurasia In The Late Pleistocene And Holocene, Maciej Sykut, Sławomira Pawełczyk, Natalia Piotrowska, Krzysztof Stefaniak, Bogdan Ridush, Daniel Makowiecki, Pavel Kosintsev, Barbara Wilkens, Tomasz Borowik, Ralph Fyfe, Jessie Woodbridge, Magdalena Niedziałkowska

School of Geography, Earth and Environmental Sciences

Red deer (Cervus elaphus) is one of the species that is rather wide spread and survived across Europe over the Holocene. The analyses of carbon and nitrogen stable isotopes in bone collagen of ungulate remains have been applied in paleoecological studies as environmental and dietary indicators. In this study we present the carbon and nitrogen stable isotope compositions of previously radiocarbon-dated red deer bone samples (N = 68) found in Central, Southern and Eastern Europe and Asia and aligned to one of two species: European red deer (Cervus elaphus) and wapiti (Cervus canadensis). We showed that the values of carbon …

Legacy Radionuclides In Cryoconite And Proglacial Sediment On Orwell Glacier, Signy Island, Antarctica, Philip N. Owens, Tim A. Stott, Will H. Blake, Geoffrey E. Millward

School of Geography, Earth and Environmental Sciences

Cryoconite is a specific type of material found on the surface of glaciers and icesheets. Samples of cryoconite were collected from the Orwell Glacier and its moraines, together with suspended sediment from the proglacial stream on Signy Island, part of the South Orkney Islands, Antarctica. The activity concentrations of certain fallout radionuclides were determined in the cryoconite, moraine and suspended sediment, in addition to particle size composition and %C and %N. For cryoconite samples (n = 5), mean activity concentrations (±1SD) of 137Cs, 210Pbun and 241Am were 13.2 ± 20.9, 66.1 ± 94.0 and 0.32 ± 0.64 Bq kg−1, respectively. …

Terrestrial Carbon Isotope Stratigraphy Of The Eocene–Oligocene Transition, Petrockstowe And Bovey Basins, Devon, Uk, Mohammed S. Chaanda, Stephen T. Grimes, Rhodri M. Jerrett, Mark Anderson, Melanie J. Leng, Meriel E. Fitzpatrick, Gregory D. Price

School of Geography, Earth and Environmental Sciences

The terrestrial sediments of the Petrockstowe and Bovey basins in Devon, UK were examined. Their age is considered to be Eocene and Oligocene. The sediments (kaolinitic clays, silts, sands, gravels, and lignites) from both basins were analysed for carbon isotopes of organic material, in conjunction with total organic carbon and palynological analyses used to unravel the type of and provenance of organic matter present. Within the Petrockstowe Basin, the lowermost interval examined shows a palynological distribution dominated by phytoclasts, whilst the upper part of the core is dominated by higher concentrations of palynomorphs (up to 90 %) and an increase …

Anticipatory Reward Dysfunction In Alcohol Dependence: An Electroencephalography Monetary Incentive Delay Task Study, Mica Komarnyckyj, Chris Retzler, Robert Whelan, Oliver Young, Elsa Fouragnan, Anna Murphy

School of Psychology

A wealth of functional magnetic resonance imaging monetary incentive delay task (MIDT) research has shown alcohol dependency is associated with a hypoactive striatal response during gain anticipation (gain > neutral) and loss anticipation (loss > neutral). Electroencephalography (EEG) holds clinical advantages over fMRI (high temporal resolution, low cost, portable) however its use to study reward processing in alcohol dependence is limited. We aimed to carry out the first EEG MIDT (eMIDT) study in alcohol dependence. 21 abstinent alcohol dependent individuals and 26 controls performed an MIDT while neural activity was recorded using 64-channel EEG. Trial averaged event-related potentials (ERPs) and single-trial machine …

Serviceability Behaviour Of Frp-Reinforced Slatted Slabs Made Of High-Content Recycled Aggregate Concrete, Thanongsak Imjai, Reyes Garcia, Boksun Kim, Chayanon Hansapinyo, Piti Sukontasukkul

School of Engineering, Computing and Mathematics

At service load levels, shear-induced deflections of reinforced concrete (RC) slabs are small and therefore they are usually ignored in deflection calculations. However, shear-induced deflections can be large in RC slabs reinforced with Fibre Reinforced Polymer (FRP) bars, especially after the development of diagonal cracks. This article investigates the serviceability behaviour (deflections and crack widths) of FRP-reinforced slatted slabs cast with recycled aggregate concrete (RAC). Fifteen slabs were tested in flexure, including five slabs cast with normal concrete (NC), five slabs cast with RAC made with 50% recycled concrete aggregate, and five slabs cast with RAC made with 100% recycled …

Anti-Capsular Activity Of Cuo Nanoparticles Against Acinetobacter Baumannii Produce Efflux Pump, Israa M.S. Al-Kadmy, Sarah Naji Aziz, Ahmed Mahdi Rheima, Suhad Abbas Abid, Ahmed Suhail, Israa Hussein Hamzah, Eman N. Naji, Alexandros Besinis, Helal F. Hetta

School of Engineering, Computing and Mathematics

Copper oxide nanoparticles are modern kinds of antimicrobials, which may get a lot of interest in the clinical application. This study aimed to detect the anti-capsular activity of CuO nanoparticles against Acinetobacter baumannii produce efflux pump. Thirty-four different clinical A. baumannii isolates were collected and identified by the phenotypic and genetic methods by the recA gene as housekeeping. Antibiotic sensitivity and biofilm-forming ability, capsular formation were carried out. The effect of CuO nanoparticles on capsular isolates was detected, the synergistic effects of a combination CuO nanoparticles and gentamicin against A. baumannii were determined by micro broth checkerboard method, and the …

Consumers' Willingness To Pay For An Animal Welfare Food Label, Matthew Gorton, Ching Hua Yeh, Elena Chatzopoulou, John White, Barbara Tocco, Carmen Hubbard, Fiona Hallam

Plymouth Business School

Consumers increasingly rate the ethical dimensions of food production, including animal welfare, as important to them but how these concerns influence their food choices remains unclear. To address this, a Discrete Choice Experiment assesses consumers' willingness to pay for chicken meat. The study aims to understand the effects of food labels (RSPCA Assured and Red Tractor), cause-related marketing campaigns, and price on consumers' willingness to pay. Drawing on a representative sample of 401 British consumers, we estimate a mixed logit model using the hierarchical Bayesian estimation method. The results for the full sample reveal a substantial price premium associated with …

Student-Led Health Promotion Toolkit: A Practice Development Project, R Reynolds, S Neill

School of Nursing and Midwifery

Student nurses are uniquely placed to contribute to health promotion during their undergraduate programmes. The aim of this practice development project was to co-develop a toolkit to facilitate student nurse led health promotion practice. The project used an emancipatory methodology to explore health promotion practice opportunities for one university cohort of student nurses in partnership with the local practice area. A person-centred framework was used to engage with students and nurses to benchmark current student practice, scope for student-led activity and develop a shared vision for the toolkit resources. The student questionnaire revealed greater confidence in health promotion knowledge than …

“I Am Not A Good Woman?” Exploring The Views And Challenges Of Nurses When Discussing Hpv Testing And Associated Cervical Screening With Women In Iraq, Suhailah M. Ali, Rebecca Lawes, Ayla Khedher Ghalib

School of Nursing and Midwifery

Introduction: Cervical cancer is mostly caused by high-risk Human papillomavirus HPV, with an estimation prevalence of HPV of 99.7% worldwide. The US Food and Drug Administration (FDA) approved an HPV test for primary cervical screening in 2014. An HPV-DNA test, which provides higher protection against invasive cervical carcinomas, is replacing the long-standing Pap smear as the primary method of cervical cancer screening. Objective: To explore nurses’ experience and knowledge of HPV DNA testing and how screening impacts on women's health through increasing awareness and proposing actions for health education strategies. Method: A qualitative exploratory study was conducted on a purposeful …

Towards The Validation Of Novel Cognitive And Physiological Indicators Of Affective State In Horses (Equus Caballus), Sarah Kappel

School of Biological and Marine Sciences Theses

Assessing animal emotions reliably is crucial for making accurate decisions about animal welfare, but subjective affective (emotional) states are inaccessible for direct measurement. We know that negative affect modulates attention in humans and some animals. The overarching aim of this thesis is to investigate if the preferential attention allocation towards certain information (i.e. attention bias, AB) could be a potential proxy measure of affective valence in horses. First, I provide an overview of the theoretical background to attention and AB by reviewing the literature on AB in humans and animals (Chapter 2). I examine which methodological aspects need consideration when …

Does Connectivity With Nature Alter Consumer Behaviour? Linking Ocean Connectedness And Consumer Views On Single-Use Packaging, Sohvi Katariina Nuojua

School of Biological and Marine Sciences Theses

Single-use packaging items constitute a large proportion of the plastic litter found in the marine environment. Consumer behaviour is a key contributor to the accumulation of this pollution in the environment. This thesis outlines correlational and experimental research on consumer responses to environmentally relevant qualities of single-use packaging. Furthermore, it considers a novel concept of ocean connectedness as a psychological moderator of consumer response. Studies 1 and 2 investigated consumer responses to recyclability of packaging as well as its raw material (plastic, glass, carton and aluminium) in undergraduate students and in a broader UK public sample. Ocean connectedness was assessed …

Ideal Models Of Good Inpatient Care For Adults With Intellectual Disability: Lessons From England, Lisa Burrows, Georgia Page, Elena Plugaru, Bridie Kent, Mahesh Odiyoor, Sujeet Jaydeokar, Jonathan Williams, Kevin Elliot, Richard Laugharne, Rohit Shankar

School of Nursing and Midwifery

Background: In recent years, a significant proportion of inpatient facilities for people with intellectual disabilities and/or autism has been de-commissioned in England, This has resulted in individuals with intellectual disabilities being sent to distant hospitals far away from their families and carers leading to challenges in follow-up, community care and interventions. The impact of de-institutionalisation, has often caused patient trauma, family distress and subsequent discharge difficulties. Not every individual with intellectual disabilities and/or autism requires inpatient care but inpatient care when needed has to be local, adequate and appropriate. Aims: To evaluate current evidence of utility of inpatient models for …

Pleistocene Depositional Environments On The Eastern Ross Sea Continental Slope, Antarctica, Maxine Valentina King

School of Biological and Marine Sciences Theses

In 2018, International Ocean Discovery Program Expedition 374 drilled a 208.28 m-thick sequence of Plio-Pleistocene sediments on the Eastern Ross Sea continental slope, Antarctica (Hole U1525A). In this thesis, sediments from Hole U1525A are used to reconstruct the depositional environment on the slope since 2.4 Ma, focusing on characterising instances of West Antarctic Ice Sheet (WAIS) extension to the continental margin. Late Pleistocene Ross Sea Fan deposits in Hole U1525A are also studied to identify provenance changes that may link to changing ice stream dynamics. Core images, grain size, X-ray fluorescence and physical properties datasets were used from the upper …

Editorial: Case Reports In Cardio-Oncology: 2022, Michael S Ewer, Syed Wamique Yusuf, Reto Asmis, Jun-Ichi Abe

Faculty, Staff and Student Publications

No abstract provided.

Editorial: Women In Molecular And Cellular Oncology, Petranel T Ferrao, Laura Rosanò, Valeria Poli, Shilpa S Dhar, Ana Paula Lepique

Faculty, Staff and Student Publications

No abstract provided.

Editorial: Women In Molecular And Cellular Oncology, Volume Ii: 2022, Shilpa S Dhar

Faculty, Staff and Student Publications

No abstract provided.

Editorial: The Interplay Between Microbiota And Allergen In Shaping Respiratory Mucosa Immunity: Role In Development Of Asthma, Zhenwei Xia, Wenwei Zhong, Min Wu, Scott E Evans

Faculty, Staff and Student Publications

No abstract provided.

A Cross-Sectional Study To Test Equivalence Of Low- Versus Intermediate-Flip Angle Dynamic Susceptibility Contrast Mri Measures Of Relative Cerebral Blood Volume In Patients With High-Grade Gliomas At 15 Tesla Field Strength, Mark S Shiroishi, Dane Weinert, Steven Y Cen, Bino Varghese, Timothy Dondlinger, Melissa Prah, Jesse Mendoza, Sina Nazemi, Nima Ameli, Negin Amini, Salman Shohas, Shannon Chen, Bavrina Bigjahan, Gabriel Zada, Thomas Chen, Josh Neman-Ebrahim, Eric L Chang, Frances E Chow, Zhaoyang Fan, Wensha Yang, Frank J Attenello, Jason Ye, Paul E Kim, Vishal N Patel, Alexander Lerner, Jay Acharya, Leland S Hu, C Chad Quarles, Jerrold L Boxerman, Ona Wu, Kathleen M Schmainda

Faculty, Staff and Student Publications

INTRODUCTION: 1.5 Tesla (1.5T) remain a significant field strength for brain imaging worldwide. Recent computer simulations and clinical studies at 3T MRI have suggested that dynamic susceptibility contrast (DSC) MRI using a 30° flip angle ("low-FA") with model-based leakage correction and no gadolinium-based contrast agent (GBCA) preload provides equivalent relative cerebral blood volume (rCBV) measurements to the reference-standard acquisition using a single-dose GBCA preload with a 60° flip angle ("intermediate-FA") and model-based leakage correction. However, it remains unclear whether this holds true at 1.5T. The purpose of this study was to test this at 1.5T in human high-grade glioma (HGG) …

Editorial: Prion-Like Transmission Of Pathogenic Proteins In Neurodegenerative Diseases: Structural And Molecular Bases, Victor Banerjee, Fei Wang, Daniela Sarnataro, Claudio Soto

Faculty, Staff and Student Publications

No abstract provided.

Implementation And Outcomes Of A Comprehensive Emergency Care Curriculum At A Low-Resource Referral Hospital In Liberia: A Novel Approach To Application Of The Who Basic Emergency Care Toolkit, Alexander Mayah, Taylor Burkholder, Michael Jaung, Ahson Haider, Paul Wesseh, John Shakpeh, Corey Bills, Kayla Enriquez

Faculty, Staff and Students Publications

BACKGROUND: Emergency care is vital in low- and middle-income countries (LMICs) but many frontline healthcare workers in low-resource settings have no formal training in emergency care. To address this gap, the World Health Organization (WHO) developed Basic Emergency Care (BEC): Approach to the acutely ill and injured, a multi-day, open-source course for healthcare workers in low-resource settings. Building on the BEC foundation, this study uses an implementation science (IS) lens to develop, implement, and evaluate a comprehensive emergency care curriculum in a single emergency facility in Liberia.

METHODS: A six-month emergency care curriculum consisting of BEC content, standardized WHO clinical …

Trends In Cigarette Smoking Among United States Adolescents, Charles H Hennekens, Panagiota Kitsantas

Faculty, Staff and Students Publications

Background: Cigarette smoking remains the leading avoidable cause of premature death in the United States, accounting for approximately 500,000, or 1 in 5, deaths annually. We explored trends in cigarette smoking among US adolescents.

Methods: We used data for adolescents in grades 9 through 12 from 1991 to 2021 from the Youth Risk Behavior Survey provided by the US Centers for Disease Control and Prevention. We explored trends overall as well as by sex, race/ethnicity, and school grade.

Results: All cigarette use—assessed as ever, occasional, frequent, or daily—among adolescents declined markedly from 1991 to 2021. Specifically, ever use significantly decreased …

How Widespread And Convenient H Pylori Susceptibility Testing Will Result In Pharmacological Opportunities

Faculty, Staff and Students Publications

Introduction:

Until recently antimicrobial therapy for Helicobacter pylori infections was almost universally empirical and based on a combination of expert opinion and local effectiveness. However, the average cure rates rarely achieved more than 80%. The new requirement that all therapeutic regimens reliably achieve high cure rates, the introduction of potassium competitive acid blockers and the availability of susceptibility testing many pharmacological opportunities particularly since all current therapies will require optimization. The ability to rapidly and inexpensively obtain H. pylori susceptibility data using stool samples makes obtaining susceptibility data practical and allows using susceptibility-based therapy routinely for both treatment naïve patient …