Digital Commons Network^™

Brief Report: Out Of Sight Out Of Mind - Preventable Childhood Kidney Disease In The Far North, Johanna Neville, Allison Hempenstall, Caroline Taunton, Valmay Fisher, Malcolm Mcdonald

Journal of the Australian Indigenous HealthInfoNet

APSGN is an immune-mediated kidney disease that occurs after a Streptococcus pyogenes skin or throat infection in children and contributes to chronic kidney disease later in life. It is a disease of poverty and regrettably common in Aboriginal and Torres Strait Islander children. There have been seven documented APSGN outbreaks across Far North Queensland in the last nine years. Despite this disease being notifiable in both Western Australia and the Northern Territory, Queensland is yet to acknowledge the importance of early notification in the management of APSGN. Notification-driven publication of APSGN incidence should help raise its profile and stimulate better …

Hipaa Vs. Medical Research: Improving Patient Care Through Integration Of Data Privacy And Data Access, Katherine D'Ordine

Honors Projects in Data Science

The purpose of this research is to understand the current relationship between data access and data privacy in the health care industry and attempt to find a way that important health care research can still be conducted amidst HIPAA regulations. There is a lack of extensive research on the impacts of data privacy on health care research due to access regulations, so a survey was created regarding current data processes and recommendations for creating a healthier relationship between privacy and access for research. It was distributed to anyone in health care, analytics, or research to get a variety of perspectives. …

Functional Domains Of The Hsv-1 Ul37 Protein In Virus Infectivity And Retrograde Transport In Neurons, Carolyn Clark

LSU Doctoral Dissertations

Herpes simplex virus type 1 is large alphaherpesvirus with 20 envelope proteins and 23 tegument proteins. Virus entry is via fusion of the viral envelope with cellular membranes mediated by a complex of viral glycoproteins. Glycoprotein B (gB) is the only fusogenic glycoprotein, while other viral glycoproteins and membrane proteins including gD, gH, gL, gK and UL20 membrane protein modulate gB’s fusogenicity. Previously, Our laboratory developed the HSV-1 (VC2) vaccines strain with partial deletions in the amino termini of gK (ΔgK(31–68)) and the UL20 membrane protein (ΔUL20(4–22)). VC2 enters epithelial cells only via endocytosis followed by release of the capsid …

The Characterization Of The Sars-Cov-2 Receptor Binding Domain Interaction With The Human Ace2 Receptor And Potential Small Molecule Inhibitors, Camryn Carter

Honors Theses

In December 2019, a novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV-2), was identified in Wuhan, China after numerous patients experienced pneumonia symptoms, but existing medicinal treatments were ineffective.1 The global spread of the SARS-CoV-2 virus caused an outbreak of the infectious disease, coronavirus disease 2019 (COVID-19), which was soon after declared a pandemic by the World Health Organization, referred to as the COVID-19 pandemic. According to John Hopkins University, over 1,000,000 people have died from SARS-CoV-2 infection and about 104,000,000 cases have been confirmed in the United States (US). An infection of the SARS-CoV-2 virus is caused by the …

Prevalence And Factors Of Self-Medication With Antibiotics In Claiborne County, Tennessee, Kimberly A. Carney, Lauren Wisnieski, Tristan Lackey, Donald Noah

Journal of Appalachian Health

Introduction: Antimicrobial resistance (AMR) is a serious concern to public health, causing an estimated 35,000 deaths annually in the U.S. Misuse of antimicrobials increases the rate of AMR. Self-medication with antibiotics (SMA) is a primary contributor to AMR that can be addressed through education. SMA has been reported at rates of 3% to 66% in the U.S. but has not been evaluated in Appalachia.¹ Low health literacy and barriers to accessing care have been correlated with SMA and are common in many areas of Appalachia.

Purpose: This study aims to assess factors associated with SMA, demographic differences in knowledge …

Borrowed Wombs: On Uterus Transplants And The “Right To Experience Pregnancy”, Glenn Cohen

University of Chicago Legal Forum

No abstract provided.

Medical Waste Awareness Day, Lauren Tucker, Wyatt Walters, Savannah Withrow, Kayla Leavell

University of Montana Conference on Undergraduate Research (UMCUR)

Healthcare facilities are generators of large amounts of waste, leading to global environmental impacts that negatively impact both human health and natural systems around the world. Medical waste is usually defined quite broadly, encompassing any waste generated by a healthcare facility. Increasing use of single use plastic and single use devices has led to a large uptick in medical waste globally, especially since the onset of the COVID-19 pandemic. Globally, 4.7 billion tons of healthcare waste is produced each year, which is approximately thirty-three pounds per hospital bed per day (Overstreet, 2021). The generation and disposal of this waste leads …

Exploring Inmate Health In Prisons: Health Issues, Interventions, And Suggestions To Improve Care, Jenna Healy

Honors Program Theses and Projects

The United States has the highest number of prisoners per capita at 639 people per 100,0008. There has been a fivefold increase in the number of inmates in the United States prison systems since 197044, and this may be a major contributor to the corrections healthcare system having trouble keeping up with this growth compared to the general population of the United States. According to the World Health Organization, the United States has documented higher mortality rates than many other developed countries. Rates of conditions such as cardiovascular disease have decreased everywhere, but much less in the United States. In …

Implementation Of A Rounding Tool To Promote Compliance With Central Line Dressing Changes In An Adult Intensive Care Unit, Fabiola Demuth

DNP Projects

Abstract

Evidence supports implementing central line (CL) maintenance bundles and nurse-led rounding interventions to prevent central line-associated bloodstream infections (CLABSIs). In a Tennessee intensive care unit (ICU), increased CLABSI rates were associated with inconsistent CL dressing maintenance and documentation. This Doctor of Nursing Practice scholarly project was implemented to improve ICU CLABSI rates and reinforce nursing standard practices for CL dressing care. This quality improvement project used the Institute for Healthcare Improvement (IHI) model for improvement, which used the plan, do, study, act (PDSA) cycles as part of the framework to implement a daily nurse-led rounding tool in the ICU, …

Case Study Summary: Johnson & Johnson And Macy's Inc., Cameron Richardson

Honors Theses

This thesis, over a one-year period, covers conclusions derived from research on two different companies: Johnson & Johnson and Macy’s Inc. Through a two-semester course taken within the scope of the honors college alongside Dr. Victoria Dickinson, I, alongside my respective group members for each company, were able to compile a thorough analysis of risks and business strategies the two corporations could identify and implement to manage present and future complications. This analysis followed standard conventions of the accounting profession, as our research was focused on identifying risks and strategies affiliated with audit, tax, and advisory services, modeling how professional …

A Content Analysis Of Media Coverage Of Telehealth In Mississippi, Hailey Layne

Honors Theses

Telehealth’s utilization within healthcare has expanded and changed areas of healthcare delivery. In rural states like Mississippi barriers to accessing healthcare services exist due to demographic factors, socioeconomic factors, or geographic distance. This study was meant to look at the literature related to telehealth that was being disseminated to Mississippians through online news sources. It was noted whether these articles viewed telehealth utilization in a positive or negative way. Utilizing a cross-sectional media analysis, the news articles were screened using a coding form that acknowledged different themes in the literature. Frequency analyses were conducted to aid in interpreting the common …

From Big Farm To Big Pharma: A Differential Equations Model Of Antibiotic-Resistant Salmonella In Industrial Poultry Populations, Rilyn Mckallip

Honors Theses

Antibiotics are used in poultry production as prophylaxis, curative treatment, and growth promotion. The first use is as prophylaxis, or prevention of common bacterial diseases. The crowded conditions in concentrated animal feeding operations necessitate management of infectious disease to ensure overall animal health and the profitability of such operations. In these farms, between 20,000 and 125,000 birds are raised in shed-like enclosures [3], with an average of less than one square foot of space per chicken [34]. Antibiotics are currently used in chicken farms to manage and prevent common bacterial diseases such as respiratory and digestive tract infections, as well …

Characterizing Movement Patterns Of Nomadic Pastoralists And Their Exposure To Rift Valley Fever In Kenya, G. Mosomtai, J. L. Kasiiti, R. M. Murithi, P. Sandström, T. Landmann, O. W. Lwande, O. A. Hassan, C. Ahlm, R. Sang, M. Evander, Z. Szantoi, G. Ottavianelli

All Peer-Reviewed Publications

The role of animal movement in spreading infectious diseases is highly recognized by various legislations and institutions such as the World Organisation for Animal Health and the International Animal Health Code. The increased interactions at the nexus of human-animal-ecosystem interface have seen an unprecedented introduction and reintroduction of new zoonotic diseases with high socio-economic impacts such as the COVID-19 pandemic. Rift Valley fever (RVF) is a zoonotic disease that affects both humans and animals and is transmitted by Aedes mosquitoes or through contact with the body fluids of infected animals. This study seeks to characterize movement patterns of pastoralist and …

Editorial: Disease Biomarker Analysis Based On Optical Biosensing, Tianshu Chen, Fanben Meng, Binwu Ying, Xiaoli Zhu

Department of Mechanical and Materials Engineering: Faculty Publications

Disease biomarker analysis has become a crucial tool for diagnosing and evaluating disease prognosis, especially with the increasing understanding of diseases at the molecular level. Abnormalities in various biomarkers can indicate diseased states, and can be used to rapidly and specifically detect and quantify diseases using optical biosensing techniques (Gao et al., 2023). Optical biosensing techniques have several advantages over traditional methods including higher sensitivity, specificity, and faster analysis times (Plikusiene and Ramanaviciene, 2023). It also allows for non-invasive sample collection. With advancements in optical biosensing technology, many medical conditions including cancers, infectious diseases, and autoimmune disorders can be accurately …

Editorial: Disease Biomarker Analysis Based On Optical Biosensing, Tianshu Chen, Fanben Meng, Binwu Ying, Xiaoli Zhu

Department of Mechanical and Materials Engineering: Faculty Publications

Disease biomarker analysis has become a crucial tool for diagnosing and evaluating disease prognosis, especially with the increasing understanding of diseases at the molecular level. Abnormalities in various biomarkers can indicate diseased states, and can be used to rapidly and specifically detect and quantify diseases using optical biosensing techniques (Gao et al., 2023). Optical biosensing techniques have several advantages over traditional methods including higher sensitivity, specificity, and faster analysis times (Plikusiene and Ramanaviciene, 2023). It also allows for non-invasive sample collection. With advancements in optical biosensing technology, many medical conditions including cancers, infectious diseases, and autoimmune disorders can be accurately …

Development Of Graphene Oxide/Carbon Nanofiber Hybrid Structure, Greta Wilkins

Liberty University Research Week

Undergraduate

Applied

A Cascade Of Care Of Patients With Hepatitis C Infection In A Rural State, Wollelaw Agmas, Wendy Craig, Kathleen Fairfield, Brian F. King, Elizabeth Eisenhardt, Kinna Thakarar

Journal of Maine Medical Center

Introduction: The substance misuse epidemic has fueled an increase in hepatitis C virus (HCV) infections. Despite the availability of sensitive screening and curative treatment, relatively few people are aware of their diagnosis and engaged in care. In this study, we aimed to identify local gaps in HCV care and inform strategies for improvement.

Methods: In this retrospective study, we assessed adult patients seen at a tertiary care center from 2015 to 2019 and who were eligible for HCV screening based on recommendations from the Centers for Disease Control and Prevention. Inclusion criteria were birth from 1945 to 1965, long-term dialysis …

Analysis Of An Seir Model With Non-Constant Population, Kylar Byrd, Tess Tracy, Sunil Giri, Swarup Ghosh

Student Research

Analysis of an SEIR model with Non-Constant Population
by Kylar Byrd and Tess Tracy, with Dr. Sunil Giri and Dr. Swarup Ghosh.

Mathematical modeling can be useful in helping us to understand disease dynamics. Epidemiological models consist of differential equations with variables and parameters defined to portray these dynamics. We will be presenting the mathematics involved in formulating and analyzing a model for a disease such as influenza. We will first explain a simple SIR model, and then we will introduce our model. We will be looking at an SEIR model that incorporates the use of an exposed class as …

Spatiotemporal Analysis Of Covid-19 Lockdown Impact On The Land Surface Temperatures Of Different Land Cover Types In Louisiana, Priscilla Loh, Yaw Twumasi, Zhu H. Ning, Matilda Anokye, Diana B. Frimpong, Judith Oppong, Abena B. Asare-Ansah, Rechael Naa Dedei Armah, Caroline Y. Apraku

Student Presentations

The COVID-19 pandemic posed a serious threat to life on the entire planet, necessitating the imposition of a lockdown mechanism that restricted people’s movements to stop the disease’s spread. This period experienced a decline in air pollution emissions and some environmental changes, offering a rare opportunity to understand the effects of fewer human activities on the earth’s temperature. Hence, this study compares the changes in Land Surface Temperature (LST) that were observed prior to the pandemic (March & April 2019) and during the pandemic lockdown (March & April 2020) of three parishes in Louisiana. The data for this study was …

Join Or Die: How Deontological Moral Intuitions Complicate Cooperation Amid The Covid-19 Pandemic, Alessandro Del Ponte

Political Science Faculty Articles and Research

Tackling COVID-19 requires universal collective action: everyone must play their part to reduce the spread of the virus and quell the pandemic. Yet, some people obstinately refuse to cooperate, irrespective of the consequences for themselves and others. In this note, I illustrate a key element of human psychology that hampers cooperation amid the pandemic: deontological moral intuitions. Deontological morality prescribes that moral taboos must be followed no matter the consequences. This means that people who consider Covid vaccines a moral taboo are prepared to suffer virtually any consequence rather than take the vaccine. I discuss the evolutionary basis of deontological …

Exploring The Barriers, Facilitators, And Experiences Among Individuals Enrolled In Medication-Assisted Treatment In Middle Tennessee, Marylu J. Joseph

DNP Projects

Background: The gold standard treatment for opioid use disorder (OUD) is medication-assisted treatment (MAT), such as methadone. Although evidence suggests that discontinuing MAT through tapering increases the risk of relapse and overdose, some individuals may still desire to taper off methadone. Additionally, legislation in certain states mandates that MAT providers offer discontinuation options to patients. Providers must engage with patients in the tapering process through shared decision-making to anticipate challenges in the patients’ tapering experience. Determining the factors influencing a patient’s tapering experience will allow providers to identify risks and offer supportive measures to help patients successfully taper while avoiding …

A Primer For The Student Joining The General Thoracic Surgery Service Tomorrow: Primer 2 Of 7., Colin C. Yost, Rohun Bhagat, David Blitzer, Clauden Louis, Jason Han, Fatima G Wilder, Robert A Meguid

Student Papers, Posters & Projects

This medical student primer discusses general thoracic surgery, which involves treating pathologies involving all structures in the thorax except the heart, thoracic aorta, great vessels, and spine.

Chronicles Of Hbv And The Road To Hbv Cure, Rukaiya Bashir Hamidu, Richard R. Hann, Hie-Won Hann

Division of Gastroenterology and Hepatology Faculty Papers

Chronic hepatitis B remains a major public health concern and a leading cause of morbidity and mortality worldwide, specifically through its causative role in chronic liver disease and hepatocellular carcinoma. Worldwide, it affects up to 292 million people. In this paper, we review the historic discovery of the hepatitis B virus and chronicle the significant advances in our understanding of the virus and its interactions with the human host to cause disease. We also overview advancements in therapies for hepatitis B virus and the current absence of curative therapies and highlight on-going therapeutic efforts in search of curative therapies to …

Interactions Between Metabolism And Growth Can Determine The Co-Existence Of Staphylococcus Aureus And Pseudomonas Aeruginosa, Camryn Pajon, Marla C. Fortoul, Gabriela Diaz-Tang, Estefania Marin Meneses, Ariane R. Kalifa, Elinor Sevy, Taniya Mariah, Brandon Toscan, Maili Marcelin, Daniella M. Hernandez, Melissa M. Marzouk, Allison J. Lopatkin, Omar T. Eldakar, Robert Smith

Biology Faculty Articles

Most bacteria exist and interact within polymicrobial communities. These interactions produce unique compounds, increase virulence and augment antibiotic resistance. One community associated with negative healthcare outcomes consists of Pseudomonas aeruginosa and Staphylococcus aureus. When co-cultured, virulence factors secreted by P. aeruginosa reduce metabolism and growth in S. aureus. When grown in vitro, this allows P. aeruginosa to drive S. aureus toward extinction. However, when found in vivo, both species can co-exist. Previous work has noted that this may be due to altered gene expression or mutations. However, little is known about how the growth environment could influence the …

Champion Training For Two Clinicians Indwelling Urinary Catheter Insertion Technique, Punitha Stevenson

Liberty University Research Week

Graduate

Basic

The Promise Of Media Literacy Education When “Everything Is At Stake” And “Everything Is Expected”, Monica Bulger, Gina Baleria, Renee Hobbs, Kimberly R. Moffitt

Journal of Media Literacy Education

In the midst of a tumultuous time in American and global history, the Association for Education in Journalism and Mass Communication Annual Conference 2021 hosted a panel to explore the promise and limits of media literacy. Panelists discussed the vital role of media literacy education in responding to challenges to democracy, social justice, and public health. With “everything at stake,” the panelists moved through responses to current crises while grounding in a historical context and offering recommendations for the future. Curated transcripts share a pivotal moment when much was expected of media literacy and media literacy experts explored promise and …

Physician Stress In The Era Of Covid-19 Vaccine Disparity: A Multi-Institutional Survey, Sarah Zahl, Debasis Mondal, David Tolentino, Jennifer A Fischer, Sherry Jimenez

Rowan-Virtua School of Osteopathic Medicine Departmental Research

CONTEXT: Healthcare workers are at a high risk of infection during infectious disease outbreaks, such as the COVID-19 pandemic. Despite the availability of several vaccines against COVID-19, the absence of vaccination in patients and colleagues remains a continuous source of stress in healthcare workers. We conducted a survey of physician preceptors, both MDs and DOs, to explore the impact of differences in the patients' and colleagues' vaccination status on their well-being, stress, and burnout.

OBJECTIVES: The objective of this study is to determine whether exposure to unvaccinated patients and/or colleagues increases stress and burnout in physician preceptors by utilizing a …

Are Cross-Sectional Safety Climate Survey Results In Operating Room Staff Associated With The Surgical Site Infection Rates In Swiss Hospitals?, Yvonne Pfeiffer, Andrew Atkinson, Judith Maag, Michael A. Lane, David Schwappach, Jonas Marschall

2020-Current year OA Pubs

OBJECTIVES: The aim of this study was to investigate the association between surgical site infections (SSIs), a major source of patient harm, and safety and teamwork climate. Prior research has been unclear regarding this relationship.

DESIGN: Based on the Swiss national SSI surveillance and a survey study assessing (a) safety climate and (b) teamwork climate, associations were analysed for three kinds of surgical procedures.

SETTING AND PARTICIPANTS: SSI surveillance data from 20 434 surgeries for hip and knee arthroplasty from 41 hospitals, 8321 for colorectal procedures from 28 hospitals and 4346 caesarean sections from 11 hospitals and survey responses from …

2023-April-19-Rotation Spotlight- Sydney Fields ('23) Infectious Disease Focus At Va, Bill Gatton College Of Pharmacy, East Tennessee State University, University Marketing And Communication, East Tennessee State University

ETSU News

Meet Sydney Fields ('23), from Jacksboro, Tennessee, who experienced a rotation in infectious disease at the James H. Quillen VA Medical Center in Johnson City, Tennessee.

What does your day look like on rotation?

Each day begins with a thorough assessment of each patient on the ID service where we assess for optimization or de-escalation of antimicrobial therapy based on patient specific parameters. Once the pharmacy team has adequately assessed each patient, we collaborate with the infectious disease providers during patient care rounds where treatment plans and drug therapies are implemented. Throughout the day we continue to trend labs, follow …

Silverlon: A Weapon Against Driveline Infections In Lvad Patients, Kelsey Barrett Msn, Mba, Rn, Ccrn, Barbara A. Ebert Crnp, Martina Oswald-Remaly Msn, Rn, Ccrn, Csc

Department of Medicine

No abstract provided.