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The Minutes Of The Marshall University Board Of Governors Meeting, April 26, 2023, Marshall University Board Of Governors

Board of Governors Minutes

No abstract provided.

Communicating Health: Misinformation And Mistrust In The Age Of Coronavirus, Chris Anstead

Undergraduate Theses

With one of the most advanced medical systems in the world, the Untied States still experienced an exceedingly high COVID-19 death rate per capita. Because biomedical therapies for COVID-19 were available, the focus of this review is on the social aspects of the COVID-19 response. By observing how Americans reacted to vaccination, masking, and social distancing guidelines, as well as how those guidelines were communicated to the general population from the public and private sectors, this thesis argues that the social and political aspects of the COVID-19 pandemic played a significant role in the outcome of the pandemic response. Additionally, …

232 - A General Mortality Analysis In 19th And Early 20th Century Rochester, New York: "Exploring Sex-Based Differences In Childhood And Adolescent Mortality Rates Across Age Groups.”, Chizoba Okorie

GREAT Day Posters

This poster presentation was completed by Chizoba Okorie, under the guidance of the Faculty Advisor, Professor Kristi Krumrine, in the Department of Anthropology and Sociomedical Science. Abstract: This presentation represents the initial phase of a research study that explores health and disease in 19th-and early 20th-century Rochester. The research focuses on the prevalence of historic diseases through the transcription and analysis of cemetery records for Mount Hope Cemetery. The purpose of this study is to compare mortality rates in childhood and adolescence across different age groups of males and females. The study investigates the average ages at death, as well …

236 - Cholera, Water Sanitation, And Socioeconomic Status In 19th Century Rochester, New York, Lora Odeh

GREAT Day Posters

The completion of the Erie Canal in 1825 allowed for the rapid expansion of the City of Rochester. The creation of the Erie Canal led to the spread of infectious diseases, especially cholera, as German and Irish immigrants moved west in search of job opportunities. As the city of Rochester grew, so did cholera and other waterborne diseases. Many of these immigrants lived in overcrowded public housing, where infectious diseases like cholera were rampant, which resulted in the stigmatization of these groups. Using historic records from Mt. Hope Cemetery, this study explores how cholera and later water sanitation projects affected …

The Rise In Anti-Asian Racism And Xenophobia In The Time Of Covid-19, Mitchell Alan Kaplan

Journal of Hate Studies

As the COVID-19 pandemic continues to have a detrimental impact on the health of the American people and those abroad, the social consequences stemming from the spread of the virus have become an international crisis whose effects reach far beyond the medical issues associated with the disease. Racial and xenophobic propaganda about the illness promoted on social media platforms such as Facebook and Twitter and at campaign rallies by former President Trump has spurred a dramatic increase in anti-immigrant sentiments toward Asian Americans. The polarizing effects of the Administration’s anti-Asian rhetoric have become a battle cry that has given renewed …

Uab Researchers Awarded $19.5 Million To Study Factors That Impact Sexual Health Among Women, Public Relations

Browse All News

No abstract provided.

Human Pluripotent Stem Cell-Derived Β Cells: Truly Immature Islet Β Cells For Type 1 Diabetes Therapy?, Helen Jiang, Fang-Xu Jiang

Research outputs 2022 to 2026

A century has passed since the Nobel Prize winning discovery of insulin, which still remains the mainstay treatment for type 1 diabetes mellitus (T1DM) to this day. True to the words of its discoverer Sir Frederick Banting, “insulin is not a cure for diabetes, it is a treatment”, millions of people with T1DM are dependent on daily insulin medications for life. Clinical donor islet transplantation has proven that T1DM is curable, however due to profound shortages of donor islets, it is not a mainstream treatment option for T1DM. Human pluripotent stem cell derived insulin-secreting cells, pervasively known as stem cell-derived …

Acute Syphilitic Posterior Placoid Chorioretinitis; A Case Report And Review, Kristin Wilson, Od, Amy Garbo Maxey, Od

Optometric Clinical Practice

Background: Acute syphilitic posterior placoid chorioretinopathy (ASPPC) is a rare but defining characteristic of ocular syphilis. Clinical findings are subtle, geographic, yellowish, macular lesions, affecting the outer-retina and inner choroid, and often associated with subretinal fluid in the early phase. This case report will review the clinical signs of ASPPC to aid the practitioner in identification and recognition of its clinical importance as it relates to early diagnosis, treatment and prognosis.

Case Report: A 79-year-old African American male presented to clinic with a chief complaint of blur in the right eye for the past two days. Spectral Domain Optical Coherence …

You Can Lead A Horse To Water, Paul B. Freeman, Od

Optometric Clinical Practice

Letter from the Editor

Routine Childhood Immunization In Appalachia: A 5-Year Review Of The Prevalence, Pattern, And Predictors Of Vaccine Exemptions In Northeast Region Tennessee, Charles Olomofe, Sarah Boop, Billy Brooks, David Kirschke, Oluwafunmike Ruth Olomofe

Appalachian Student Research Forum

Background

The use of vaccines is among the most cost-effective tools for preventing infectious diseases and their complications. However, poor uptake and increasing exemption to routine childhood vaccination have been linked with outbreaks of infectious diseases such as measles, pertussis, and more recently poliomyelitis in the US. The objective of the study is to determine the prevalence, pattern, and predisposing factors of vaccine exemptions to childhood immunization amongst parents of children in the Northeast Region from 2017 to 2021.

Methods

The routine immunization data of children between 1-24 months in the Northeast region, Tennessee from 2017- 2021 was extracted. Based …

White Blood Cell Make Up In Kellback Snake Offspring Of Varying Maternal Size, Angelica Mccoy

Symposium of Student Scholars

The immune system is composed of various organs, systems, and other components with one of the most important being white blood cells. White blood cells are commonly separated into two scientific varieties, granulocytes and agranulocytes, which can be differentiated by the presence or absence of granules in the cytoplasm once stained on a slide. There are three granulocytes and two agranulocytes, each with a distinct function and shape. The ratio of these may impact the effectiveness of this portion of the immune system, and multiple factors could play a role in this ratio, an example being the size of an …

The Impact Of The Covid-19 Pandemic On Maternal Health Outcomes, Jaiden Outten, Afekwo Mary Ukuku Ph.D.

Symposium of Student Scholars

Title: The Impact of the COVID-19 Pandemic on Maternal Health Outcomes

Abstract

The COVID-19 Pandemic has disrupted access to maternal health services. Lockdowns, fear of contracting the disease, and limited access to healthcare services may have affected the overall well-being of expectant mothers and their newborns. Studies from previous infectious disease outbreaks have shown that adverse maternal outcomes have increased. Research is needed to determine the indirect impact the pandemic had on various areas of maternal health. The purpose of this study is to conduct a systematic literature review to understand the impact of COVID-19 on maternal health. A systematic …

The Effects Of Artificial Insemination On Beef Cattle In The United States, Allee R. Sweeten, Abigail Shelnut, Madison Dickey

ATU Scholars Symposium

Artificial insemination (AI) is a reproductive procedure widely used in cattle industries and other livestock to increase pregnancy rates. Breeders must wait until the animals are in the estrus part of their estrous cycle to AI. Estrus synchronization is utilized to manipulate the estrous cycle to go into estrus or standing heat. AI is conducted by loading a semen straw into an inseminating gun, inserting the gun into the vagina of the heifer, and making sure it gets past the cervix by palpating with the other hand. Once past the cervix, the semen can be distributed in the heifer. AI …

Implementation Of Health Communication In Tb Management In Indonesia, Olih Solihin, Djuara P. Lubis, Pudji Muljono, Siti Amanah

Library Philosophy and Practice (e-journal)

Tuberculosis (TB) remains a public health problem in Indonesia despite various efforts to combat it. TB is the leading cause of death in Indonesia and requires more comprehensive action, including in health communication. Indonesia ranks second after India in the number of TB cases and fourth in TB deaths in Asia. Efforts to address TB in Indonesia continue, including the implementation of more comprehensive prevention and treatment programs and effective health communication campaigns. However, the implementation of health communication in TB management in Indonesia still faces challenges such as infrastructure, policy, human resources, and community participation. Evaluation of the effectiveness …

Acute Lithiasis Cholecystitis; Particularities Of Diagnosis And Treatment In The Elderly, Adrian Silaghi, Bogdan Socea, Petrisor Banu, Vlad Dumitru Baleanu, Dragos Epistatu, Ioana Paunica, Vlad Denis Constantin

Journal of Mind and Medical Sciences

Objectives. The incidence of acute cholecystitis increases with age, when patients usually associate additional comorbidities. Such comorbidities and the late presentation to the doctor make the treatment more complex, associating higher rates of complications. The present study aims to evaluate the methods of diagnosis and treatment applied to a group of older patients with acute cholecystitis. Materials and Methods. 585 patients were enrolled in the study between 2019 and 2023. The inclusion criteria in the study were represented by the presence of the diagnosis of acute cholecystitis in patients over 65 years of age, while patients who presented complex locoregional …

Anxio-Depressive Disorders In A Pandemic Context: A Comparative Analysis: Year 2019 Versus 2020, Andreea Roxana Droahnă, Lavinia-Alexandra Moroianu, Valeria-Anca Pietroșel, Cristina Ioana Bica, Teodor Salmen, Cecilia Curis, Emanuele Maria Merlo, Roxana Adriana Stoica, Marius Moroianu

Journal of Mind and Medical Sciences

The outbreak of SARS-CoV-2 pandemic has resulted in increased rates of anxiety and depression worldwide. Objective. To comparatively evaluate factors associated with the psychological impact of Coronavirus disease between 2019 and the pandemic year 2020. Materials and Methods. The study was performed on a group of 3224 patients, of which 197 were hospitalized, selected from Jan 1st 2019 until 30th Dec 2020 in a tertiary care center for psychiatric disorders. Data were collected from the observation charts. Results. The incidence of anxiety disorders is higher in the age range 40-70 years with an average value of 53 years old. In …

The Inherited Intestinal Microbiota From Myeloid-Specific Zip8ko Mice Impairs Pulmonary Host Defense Against Pneumococcal Pneumonia, Derrick R. Samuelson, Deandra R. Smith, Kelly C. Cunningham, Sabah Haq, Daniel N. Villageliú, Christi Christi Ellis, Niaz Bahar Chowdhury, Amanda E. Ramer-Tait, Jeff Price, Daren L. Knoell

Food for Health: Publications

Intestinal dysbiosis increases susceptibility to infection through the alteration of metabolic profiles, which increases morbidity. Zinc (Zn) homeostasis in mammals is tightly regulated by 24 Zn transporters. ZIP8 is unique in that it is required by myeloid cells to maintain proper host defense against bacterial pneumonia. In addition, a frequently occurring ZIP8 defective variant (SLC39A8 rs13107325) is strongly associated with inflammation-based disorders and bacterial infection. In this study, we developed a novel model to study the effects of ZIP8-mediated intestinal dysbiosis on pulmonary host defense independent of the genetic effects. Cecal microbial communities from a myeloid-specific Zip8 knockout mouse …

The Impact Of Champion Training On A Two-Clinician Indwelling Urinary Catheter Insertion Technique To Prevent Catheter Associated Urinary Tract Infection (Cauti), Punitha Stevenson

Doctoral Dissertations and Projects

Catheter-associated urinary tract infections are a most common and preventable health care associated infection. Approximately 15% to 25% of hospitalized patients receive a urinary catheter during their hospital stay. The PICOT question that guided this quality improvement project was: How does a two-clinician indwelling urinary catheter insertion technique affect the CAUTI rate over one month in one unit? To answer the question, 19 high-quality studies that met the inclusion and exclusion criteria were reviewed. These articles recommended using CAUTI bundle and champion training by the Centers for Disease Control and Prevention to reduce CAUTIs and catheter days. This evidence-based intervention …

Activation Of The Plasmodium Egress Effector Subtilisin-Like Protease 1 Is Mediated By Plasmepsin X Destruction Of The Prodomain, Sumit Mukherjee, Armiyaw S. Nasamu, Kelly C. Rubiano, Daniel E. Goldberg

2020-Current year OA Pubs

Following each round of replication, daughter merozoites of the malaria parasite Plasmodium falciparum escape (egress) from the infected host red blood cell (RBC) by rupturing the parasitophorous vacuole membrane (PVM) and the RBC membrane (RBCM). A proteolytic cascade orchestrated by a parasite serine protease, subtilisin-like protease 1 (SUB1), regulates the membrane breakdown. SUB1 activation involves primary autoprocessing of the 82-kDa zymogen to a 54-kDa (p54) intermediate that remains bound to its inhibitory propiece (p31) postcleavage. A second processing step converts p54 to the terminal 47-kDa (p47) form of SUB1. Although the aspartic protease plasmepsin X (PM X) has been implicated …

A Rare Case Of Autopsy Proven Achromobacter Xylosoxidans Endocarditis Involving Tricuspid Valve: A Case Report, Chaitra Janga, Mackenzie Kramer, Ifrah Naeem, Lucy Checchio, Md, Zahra Qamar

Abington Jefferson Health Papers

Infective endocarditis refers to infection of one or more valves of the heart, with Achromobacter xylosoxidans (A. xylosoxidans) being a rare cause. So far, 24 cases of A. xylosoxidans endocarditis were reported, with only one case describing tricuspid valvular involvement. Despite the rarity of A. xylosoxidans endocarditis, it is important for clinicians to be aware of atypical presentation and the high mortality associated with it. We present an autopsy-proven case of tricuspid valve endocarditis in the setting of A. xylosoxidans bacteremia in a 43-year-old female.

The Effectiveness Of Increasing Frequency Of Central-Line Dressing Changes And Monitoring On Clabsi Rates: A Scoping Review, Jacob Schmidt, Bsn, Rn, Ccrn, Georgia Brown, Bsn, Rn, Laura Dickey, Agpcnp-C, Lauren Faulkner, Bsn, Rn, Margaret Harvey, Phd, Aprn, Acnp-Bc, Chfn

Doctor of Nursing Practice Projects

Abstract

Purpose/Background

Central lines provide many benefits to critically ill patients; however, there are additional risks with them, including central line-associated bloodstream infections (CLABSIs). CLABSIs place patients at increased risk for morbidity and mortality, longer length of stay, and higher medical costs. Studies evaluating various methods of reducing CLABSIs have been performed. This scoping review was completed to determine the effectiveness of frequent central-line dressing changes and increased monitoring on the incidence of central-line associated blood stream infections in adults with central-lines.

Methods

An extensive database search through the University of Tennessee Health Science Center (UTHSC) Online Library was performed …

Rapid Escape Of New Sars-Cov-2 Omicron Variants From Ba2-Directed Antibody Responses, Aiste Dijokaite-Guraliuc, Raksha Das, Daming Zhou, Helen M Ginn, Chang Liu, Helen M E Duyvesteyn, Jiandong Huo, Rungtiwa Nutalai, Piyada Supasa, Muneeswaran Selvaraj, Thushan I De Silva, Megan Plowright, Thomas A H Newman, Hailey Hornsby, Alexander J Mentzer, Donal Skelly, Thomas G Ritter, Nigel Temperton, Paul Klenerman, Eleanor Barnes, Susanna J Dunachie, Optic Consortium, Cornelius Roemer, Thomas P Peacock, Neil G Paterson, Mark A Williams, David R Hall, Elizabeth E Fry, Juthathip Mongkolsapaya, Jingshan Ren, David I Stuart, Gavin R Screaton

Faculty, Staff and Student Publications

In November 2021, Omicron BA.1, containing a raft of new spike mutations, emerged and quickly spread globally. Intense selection pressure to escape the antibody response produced by vaccines or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection then led to a rapid succession of Omicron sub-lineages with waves of BA.2 and then BA.4/5 infection. Recently, many variants have emerged such as BQ.1 and XBB, which carry up to 8 additional receptor-binding domain (RBD) amino acid substitutions compared with BA.2. We describe a panel of 25 potent monoclonal antibodies (mAbs) generated from vaccinees suffering BA.2 breakthrough infections. Epitope mapping shows potent …

Parental Help-Seeking Behaviour For, And Care Of, A Sick Or Injured Child During The Covid-19 Pandemic: A European Online Survey, Chantal D. Tan, Silvia Bressan, Rachel Carter, Mia Hylén, Inger Kristensson, Monica Lakhanpaul, Santiago Mintegi, Henriette A. Moll, Sarah Neill

School of Nursing and Midwifery

Background Globally, the COVID-19 pandemic had a huge impact on patients and healthcare systems. A decline in paediatric visits to healthcare settings was observed, which might have been due to lower incidence of injury and infectious illness, changes in healthcare services and parental concern. The aim of our study was to examine parental experiences of help-seeking for, and care of, a sick or injured child during COVID-19 lockdown periods in five European countries with different healthcare systems in place. Methods An online survey for parents with a child with any kind or illness of injury during COVID-19 lockdowns was circulated …

The Artist's Arsenal: Hiv+ Women Artists, The ‘War On Aids’, And Reclaiming Illness Narratives, Mekha Varghese

Art and Art History Honors Papers

This work uses the methodologies of both art history and medical sociology through the ‘syndemic’ framework to engage in close readings of two selected artworks, Exit (1997) by Nancer LeMoins and Violation of Africa (1984) by Affrekka Jefferson. An interdisciplinary approach to these works enables consideration of how multiple marginalized identities—i.e., living with a stigmatized illness, being a woman, being LGBTQIA+, being a person of color—appear in visual art and shape illness experience; these ideas are investigated through a formal and iconographic reading of the selected artworks. Placing art as the foundation of this analysis reveals its astounding impact and …

The Buck Stops Somewhere: An Analysis Of Global Governmental Responses To Covid-19, David Roundy

Honors Projects in History and Social Sciences

This study reviews a global sample of noteworthy governmental responses to the COVID-19 pandemic. The coronavirus first discovered in 2019, officially known as SARS-CoV-2, sparked radical change in every country across the globe, but as we enter the post-pandemic era, it is clear that some nations fared better than others when it came to addressing the situation. Some countries were better prepared to handle a viral outbreak before COVID-19 even began to spread, while others were aided by swift and effective leadership to ensure national success in the face of an international dilemma. This study makes use of both qualitative …

Splenic Asssessment Of The Toxicological Effects Of Dietary Consumption Of Pfbs (Perfluorobutane Sulfonic Acid), Janelene Sanders

Honors College Theses

Perfluoroalkyl and polyfluoroalkyl substances (PFAs) are synthetic chemicals that can pose adverse health effects such as kidney cancer, thyroid disease, pregnancy complications and liver damage due to human exposure in food and drinking water. In this study, the class of PFAs that will be investigated is Perfluorobutane sulfonic acid (PFBS), which is commonly found in the environment and consumer products such as wastewater, dust, and floor cleaners, and consists of 4 carbon chain bonded with fluorine and a sulfonic acid functional group. To accomplish study goals, PFBS, a shorter carbon chain length was ingested by Sprague Dawley rats. Serum LDH …

Media Release Q1 23, Credit Suisse

Documents

No abstract provided.

Credit Suisse Reports Pre-Tax Income Of Chf 12.8 Bn With A Cet1 Ratio Of 20.3% In 1q23; Results Reflect Write-Down Of Chf 15 Bn At1 Capital Notes, Credit Suisse

Documents

No abstract provided.

Covid-19 Coagulopathies: Highlights Of 2020–2021 Reported Data, Shreya Anil Kumar, Anushka Pradhan, Abdelrahman Elsebaie, Karina Fainchtein, Abdelrahman Noureldin, Yousra Tera, Sajida Kazi, Maha Othman

The University of Louisville Journal of Respiratory Infections

Background: The COVID-19 pandemic has evolved dramatically over the past two years, and literature on COVID-19 coagulopathy has been overwhelming, which complicates the process of understanding the literature or assessing the quality of the data available. The objective of this narrative review was to highlight and analyze data reported on COVID-19-induced coagulopathy and its outcomes in patients with severe or critical disease over two years of the pandemic.

Methods: Studies published in high-impact journals reporting on hospitalized adult COVID-19 patients, their coagulation parameters, and their thrombotic complications were included. We searched MEDLINE, Embase, and Ovid between Dec 1, 2019 and …

Comparing Levels Of Situational Empathy Based On Medium Of Exposure To Covid-19 Mortality Information And Vaccination Status, Kaylee Ries

Honors Projects

Psychophysical numbing, compassion fading, and the singularity effect are strongly affecting the world amidst the COVID-19 pandemic. Empathy motivated prosocial behavior is not consistent with the drastic number of lives lost due to COVID-19. The current study evaluated participants for situational empathy levels post exposure to either COVID-19 death statistics or a personal reflection on loss due to COVID-19. Alongside empathy, vaccination status was measured as a potential moderator on the relationship between medium of exposure to mortality information and empathy levels in the sample. 68 students were considered for this study. There was not a significant relationship between situational …