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2023

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Calcifying Odontogenic Cyst – A Three-Dimensional Radiological Evaluation By Cone Beam Computed Tomography, Karthik Rajaram Mohan, Saramma Mathew Fenn, Ramachandra Reddy Venkatesha Jan 2023

Calcifying Odontogenic Cyst – A Three-Dimensional Radiological Evaluation By Cone Beam Computed Tomography, Karthik Rajaram Mohan, Saramma Mathew Fenn, Ramachandra Reddy Venkatesha

International Arab Journal of Dentistry

Calcifying odontogenic cysts is an odontogenic cyst that gives rise to painless swelling which expand and occasionally perforate bone. Most of them are between 2 to 4 cm in diameter. Approximately 75% occur in anterior canine-incisor region. The highest incidence of occurrence is between 10 and 29 years. Radiographically they appear as well-circumscribed, unilocular cystlike areas with scattered radiopacities which range from mere flecks to large masses. The related tooth usually gets displaced. Radiopaque flecks occur in radiographic features of some lesions which undergo osteolysis during their development. They occur as a result of dystrophic calcifications in long standing chronic …


Rehabilitation Of A Patient With Single Complete Tooth-Supported Overdenture Against The Unmodified Natural Dentition Using Functionally Generated Path Technique: A Case Report, Akanksha Shinde, Nilesh Bulbule, Varun Bhatt, Gayathri Balachandran, Amit Jagtap Jan 2023

Rehabilitation Of A Patient With Single Complete Tooth-Supported Overdenture Against The Unmodified Natural Dentition Using Functionally Generated Path Technique: A Case Report, Akanksha Shinde, Nilesh Bulbule, Varun Bhatt, Gayathri Balachandran, Amit Jagtap

International Arab Journal of Dentistry

Meyer’s proposed chew-in technique also called functionally generated path (FGP) technique, is indicated for the restoration of an edentulous arch that is opposed by natural teeth as it does seem to provide the most accurate method of recording occlusal patterns, also help to minimize the effects of negative factors, and to overcome the deficiencies of articulators. As stated by Rudd and Morrow, this technique is especially suitable for tooth-supported complete dentures, due to inherent stability of tooth-supported record bases helps in recording jaw relationships accurately. Whenever a single complete denture is opposed by natural dentition, problems observed are abrasion of …


Outdoor Commercial Buildings: A Cfd Study Of The Impact Of Streets Layout On Airflow., Basma Maged, Bakr Gomaa, Alaa Sarhan Jan 2023

Outdoor Commercial Buildings: A Cfd Study Of The Impact Of Streets Layout On Airflow., Basma Maged, Bakr Gomaa, Alaa Sarhan

Mansoura Engineering Journal

The impact of the general layout of commercial streets and their orientation relative to prevailing wind direction on urban comfort due to natural ventilation is unknown. To study the natural airflow pattern in the commercial street mall, this research investigates the impact of different building layouts on airflow characteristics. To do this we conduct a parametric CFD simulation for 12 simulation cases, in which the commercial street layout changes to include secondary streets in four different cases. All cases are also subjected to three different wind directions. The study highlights that different wind orientations can significantly impact pedestrian comfort in …


Deep Learning-Based Technique For The Perception Of The Cervical Cancer, Aya Haraz, Hossam El-Din Moustafa, Abeer Twakol Khaleel, Ahmed H. Eltanboly Jan 2023

Deep Learning-Based Technique For The Perception Of The Cervical Cancer, Aya Haraz, Hossam El-Din Moustafa, Abeer Twakol Khaleel, Ahmed H. Eltanboly

Mansoura Engineering Journal

In third-world countries, cervical cancer is the most prevalent and leading cause of death. It is affected by a variety of factors, including smoking, poor nutritional status, immunological inadequacy, and prolonged use of contraception. The Pap smear test, which is intended to prevent cervical cancer, finds preneoplastic changes in cervical epithelial cells. This study framework classified cervical cancer cells from Pap smears into five specified cell types using machine learning-based classification algorithms. The SIPaKMeD database is used in this investigation. This public dataset, which was manually cropped from 966 cluster cell images taken from Pap smear slides, has 4045 isolated …


Green Roofs To Treat The Local Dwelling Environment Problems Within Egypt's Vision 2030, Abdullah Badawy Mohammed Jan 2023

Green Roofs To Treat The Local Dwelling Environment Problems Within Egypt's Vision 2030, Abdullah Badawy Mohammed

Mansoura Engineering Journal

The continuous increase in the building ratio to green areas led to disappearing green spaces, and the vertical and horizontal expansion of dwellings as an urgent demand in cities led to various environmental, social, and economic risks. Hence, the research aims to facilitate the application of green roofs for their positive role in treating these risks and improving the performance of dwelling projects and all buildings according to the climate and local conditions. Therefore, the study addressed the history, concept, and significance of green roofs, besides their benefits on architectural and urban levels, according to the three sustainability pillars and …


Early Liver Disease Diagnosis Using Grey Wolf Optimization Algorithm, Abrar Rizk M. Khedr, Ahmed I. Saleh, Ahmed S. Samra, Eman Abdelhalim Jan 2023

Early Liver Disease Diagnosis Using Grey Wolf Optimization Algorithm, Abrar Rizk M. Khedr, Ahmed I. Saleh, Ahmed S. Samra, Eman Abdelhalim

Mansoura Engineering Journal

Every year, millions of people around the world experience health issues due to liver disease, and It is also being a major global cause of mortality. A variety of factors, such as obesity and hepatitis infection, can harm the liver and contribute to these disorders. However, diagnosis of chronic liver disease is often an expensive and complex process, and early detection of liver disease poses challenges because of its elusive symptoms that can often lead to delayed diagnosis. We employed machine learning for this study, to anticipate individuals with liver diseases before symptoms appear. To attain the best accuracy, we …


Clean Vehicles Tax Credits Under The Us Inflation Reduction Act: Friend-Shoring Takes Centre Stage In Us Policy, J. Anthony Vanduzer Jan 2023

Clean Vehicles Tax Credits Under The Us Inflation Reduction Act: Friend-Shoring Takes Centre Stage In Us Policy, J. Anthony Vanduzer

Indian Journal of International Economic Law

The international market has recently faced significant disruptions owing to major geo-political events such as the Covid-19 Pandemic and the Russia-Ukraine War, resulting in unreliable and erratic global supply chains. In a bid to create and secure more sustainable supply networks, countries have adopted ‘friend-shoring’ policies, encouraging their enterprises to source supplies from friendly or allied nations. While the primary objective of these policies is to stabilize global supply chains, these initiatives also stem from a desire to reduce reliance on countries that pose a threat to the geopolitical order.

Although tailored as a market-based strategy, these friend- shoring policies, …


Asymmetric Challenges In Cybersecurity Among Wto Members : A Justification For A Veiled Trade Barrier?, Daniel Oluwadayo Akindipe, Love Gbenga-Fabusiwa Jan 2023

Asymmetric Challenges In Cybersecurity Among Wto Members : A Justification For A Veiled Trade Barrier?, Daniel Oluwadayo Akindipe, Love Gbenga-Fabusiwa

Indian Journal of International Economic Law

There is a higher prevalence of cyberattacks amongst the least developed and the developing country members of the World Trade Organization (WTO) than its developed country members. To proffer appropriate safeguards against cyberthreats, developed country members are adopting solutions outside of the WTO with Preferential Trade Agreements that specifically make provision on cybersecurity. Normative doctrinal research methodology was used in this research to analyze applicable legislation and rules that are applicable to the WTO members in the area of cybersecurity. The study revealed that the WTO does not have adequate provisions regarding the cybersecurity challenges of its least developed and …


“I Alone Can’T Stop The Spread”: Mid-Level Conduct Professionals Sensemaking Through Covid-19, Benjamin S. Selznick, Cover Heishman Jan 2023

“I Alone Can’T Stop The Spread”: Mid-Level Conduct Professionals Sensemaking Through Covid-19, Benjamin S. Selznick, Cover Heishman

Journal of Higher Education & Student Affairs

The purpose of this qualitative study is to explore how mid-level student conduct professionals (SCPs) made meaning of their professional and mid-level leadership experiences during their institutions’ immediate responses to the COVID-19 pandemic. This study draws on sensemaking as a theoretical lens and literature related to mid-level professionals and student conduct practice to ground its inquiry. Interview data was collected and analyzed from four senior-level student conduct professionals within a single State within the Southern Association of Colleges and Schools Commission on Colleges (SACSCOC) accreditation region. Findings center on three key themes voiced by the participants: the importance of maintaining …


Transgender And Gender Non-Conforming College Students’ Challenges, Supports, And Successes: An Interpretative Phenomenological Analysis, Jennifer R. Curry, Imre Csaszar, Tiffany Shierling Jan 2023

Transgender And Gender Non-Conforming College Students’ Challenges, Supports, And Successes: An Interpretative Phenomenological Analysis, Jennifer R. Curry, Imre Csaszar, Tiffany Shierling

Journal of Higher Education & Student Affairs

We report findings from an interpretative phenomenological analysis (IPA) study of transgender and gender non-conforming (TGNC) participants’ perceptions of their on-campus experiences. Participants reported their lived experiences of campus culture in the Deep South. The data was viewed through a minority stress framework. Four major themes emerged: a) supports for students; b) barriers for students; c) undergoing personal change; and d) influencing systemic change.


Warm Land Surface Temperatures And Eastern Asian Homo, Robert Patalano, Hong Yang Jan 2023

Warm Land Surface Temperatures And Eastern Asian Homo, Robert Patalano, Hong Yang

Biological and Biomedical Sciences Department Faculty Journal Articles

Climate change and hominin evolution are inextricably linked. Pleistocene climate variability, for example, is thought to have had major influences on hominin morphology, brain size, and diversity. However, clear cause-and-effect relationships between specific climatic events and major evolutionary occurrences are difficult to establish due to temporal and spatial gaps in paleoclimatic, paleoenvironmental, and archaeological records. A new branched GDGT paleotemperature record from the Lantian Basin of Central China (Lu et al., 2022), a location known for the earliest hominin presence in East Asia, illustrates warm land surface temperatures over a two-million-year period between 2.6 and 0.6 Ma, a critical time …


Deep Ecology, Nature Spirits, And The Filipino Transpersonal Worldview, Carl Lorenz Cervantes Jan 2023

Deep Ecology, Nature Spirits, And The Filipino Transpersonal Worldview, Carl Lorenz Cervantes

International Journal of Transpersonal Studies Advance Publication Archive

Many Filipinos today still believe that the world is filled with invisible entities who can affect their lives in a tangible way. These beings usually reside in nature as the souls of ancestors or other mysterious spirits. This indigenous transpersonal worldview implies that the individual is part of a living world. The modern term “deep ecology” seems to be aligned with this worldview. This paper looks at the implications of the Filipino transpersonal worldview on policies related to the care for environment and biodiversity.


Leveraging Data, Models And Farming Innovation To Prevent, Prepare For And Manage Pest Incursions: Delivering A Pest Risk Service For Low-Income Countries, Bryony Taylor, Henri Edouard Zefack Tonnang, Tim Beale, William Holland, Mary Lucy Oronje, Elfatih Mohamed Abdel-Rahman, David Onyango, Cambria Finegold, Jessica Zhu, Stefania Pozzi, Sean T. Murphy Jan 2023

Leveraging Data, Models And Farming Innovation To Prevent, Prepare For And Manage Pest Incursions: Delivering A Pest Risk Service For Low-Income Countries, Bryony Taylor, Henri Edouard Zefack Tonnang, Tim Beale, William Holland, Mary Lucy Oronje, Elfatih Mohamed Abdel-Rahman, David Onyango, Cambria Finegold, Jessica Zhu, Stefania Pozzi, Sean T. Murphy

All Peer-Reviewed Publications

Globally, pests (invertebrates, vertebrates, pathogens, weeds) can cause estimated annual losses of between 20% and 40%, but higher losses are disproportionately experienced by many low-income countries, as agriculture is the mainstay of the majority of the people and of national economies. Pests pose a major barrier to these countries’ ability to meet the aims of the UN Sustainable Development Goals (SDGs), particularly SDG2, “End hunger, achieve food security and improved nutrition and promote sustainable agriculture.” However, solutions, in the form of pest risk alert systems, coupled with major advances in technology, are now providing opportunities to overcome this barrier in …


Awareness Of Social Care Needs In People With Epilepsy And Intellectual Disability, A. Gabrielsson, S. Tromans, H. Newman, P. Triantafyllopoulou, A. Hassiotis, P. Bassett, L. Watkins, I. Sawhney, M. Cooper, L. Griffiths, A. Pullen, A. Roy, H. Angus-Leppan, Rh Thomas, M. Kinney, P. Tittensor, R. Shankar Jan 2023

Awareness Of Social Care Needs In People With Epilepsy And Intellectual Disability, A. Gabrielsson, S. Tromans, H. Newman, P. Triantafyllopoulou, A. Hassiotis, P. Bassett, L. Watkins, I. Sawhney, M. Cooper, L. Griffiths, A. Pullen, A. Roy, H. Angus-Leppan, Rh Thomas, M. Kinney, P. Tittensor, R. Shankar

Peninsula Medical School

Background: Nearly a quarter of people with intellectual disability (ID) have epilepsy with large numbers experiencing drug-resistant epilepsy, and premature mortality. To mitigate epilepsy risks the environment and social care needs, particularly in professional care settings, need to be met. Purpose: To compare professional care groups as regards their subjective confidence and perceived responsibility when managing the need of people with ID and epilepsy. Method: A multi-agency expert panel developed a questionnaire with embedded case vignettes with quantitative and qualitative elements to understand training and confidence in the health and social determinants of people with ID and epilepsy. The cross-sectional …


An Evidence-Based Approach To Provide Essential And Desirable Components To Develop Surveys On Sudden Unexpected Death In Epilepsy (Sudep) For Doctors: A Focused Review, L. V. Watkins, S. Ashby, J. Hanna, W. Henley, R. Laugharne, R. Shankar Jan 2023

An Evidence-Based Approach To Provide Essential And Desirable Components To Develop Surveys On Sudden Unexpected Death In Epilepsy (Sudep) For Doctors: A Focused Review, L. V. Watkins, S. Ashby, J. Hanna, W. Henley, R. Laugharne, R. Shankar

Peninsula Medical School

Sudden Unexpected Death in Epilepsy (SUDEP) is a major concern for people with epilepsy, their families, their care givers, and medical professionals. There is inconsistency in the SUDEP counselling doctors provide, compared to what is recommended in clinical guidelines. Numerous national and international surveys have highlighted how epilepsy professionals, usually doctors, deliver SUDEP risk counselling, particularly, when they deliver it and to whom. These surveys help understand the unmet need, develop suitable strategies, and raise awareness among clinicians with the eventual goal to reduce SUDEPs. However, there is no standardised survey or essential set of questions identified that can be …


Cardiovascular Risk Factors In Secondary Progressive Multiple Sclerosis: A Cross‐Sectional Analysis From The Ms‐Stat2 Randomized Controlled Trial, Thomas Williams, Nevin John, Alberto Calvi, Alessia Bianchi, Floriana De Angelis, Anisha Doshi, Sarah Wright, Madiha Shatila, Marios C. Yiannakas, Fatima Chowdhury, Jon Stutters, Antonio Ricciardi, Ferran Prados, David Macmanus, Marie Braisher, James Blackstone, Olga Ciccarelli, Cam Gandini Wheeler‐Kingshott, Frederik Barkhof, Jeremy Chataway, Jeremy Hobart Jan 2023

Cardiovascular Risk Factors In Secondary Progressive Multiple Sclerosis: A Cross‐Sectional Analysis From The Ms‐Stat2 Randomized Controlled Trial, Thomas Williams, Nevin John, Alberto Calvi, Alessia Bianchi, Floriana De Angelis, Anisha Doshi, Sarah Wright, Madiha Shatila, Marios C. Yiannakas, Fatima Chowdhury, Jon Stutters, Antonio Ricciardi, Ferran Prados, David Macmanus, Marie Braisher, James Blackstone, Olga Ciccarelli, Cam Gandini Wheeler‐Kingshott, Frederik Barkhof, Jeremy Chataway, Jeremy Hobart

Peninsula Medical School

Background and purpose.There is increasing evidence that cardiovascular risk (CVR) contributes to disability progression in multiple sclerosis (MS). CVR is particularly prevalent in secondary progressive MS (SPMS) and can be quantified through validated composite CVR scores. The aim was to examine the cross‐sectional relationships between excess modifiable CVR, whole and regional brain atrophy on magnetic resonance imaging, and disability in patients with SPMS. Methods. Participants had SPMS, and data were collected at enrolment into the MS‐STAT2 trial. Composite CVR scores were calculated using the QRISK3 software. Prematurely achieved CVR due to modifiable risk factors was expressed as QRISK3 premature CVR, …


Goal-Directed Haemodynamic Therapy Improves Patient Outcomes In Kidney Transplantation, J Fabes, Midani A Al, As Sarna, Dh Hadi, Sa Naji, Nr Banga, Gl Jones, Pd Berry, Md Wittenberg Jan 2023

Goal-Directed Haemodynamic Therapy Improves Patient Outcomes In Kidney Transplantation, J Fabes, Midani A Al, As Sarna, Dh Hadi, Sa Naji, Nr Banga, Gl Jones, Pd Berry, Md Wittenberg

Peninsula Medical School

Introduction: Kidney transplant graft function depends on optimised haemodynamics. However, high fluid volumes risk hypervolaemic complications. The Edwards Lifesciences ClearSight™ device permits fluid titration through markers of preload and beat-to-beat blood pressure monitoring. We evaluated the implementation of a novel goal-directed haemodynamic therapy protocol to determine whether patient outcomes had improved. Design: A retrospective evaluation of standard care versus goal-directed haemodynamic therapy in adults undergoing kidney transplantation was performed in a single centre between April 2016 and October 2019. Twenty-eight standard-of-care patients received intraoperative fixed-rate infusion and 28 patients received goal-directed haemodynamic therapy. The primary outcome was volume of fluid …


Fast-Track Extubation After Orthotopic Liver Transplant Associates With Reduced Incidence Of Acute Kidney Injury And Renal Replacement Therapy: A Propensity-Matched Analysis, J Fabes, G Wells, Z Abdi, R Bhatia, P Muehlschlegel, M Fortune-Ely, D Krzanicki, S Rahman, M Spiro Jan 2023

Fast-Track Extubation After Orthotopic Liver Transplant Associates With Reduced Incidence Of Acute Kidney Injury And Renal Replacement Therapy: A Propensity-Matched Analysis, J Fabes, G Wells, Z Abdi, R Bhatia, P Muehlschlegel, M Fortune-Ely, D Krzanicki, S Rahman, M Spiro

Peninsula Medical School

Introduction Liver transplantation is the only available definitive treatment for end-stage liver disease and subtypes of hepatocellular carcinoma. Patient outcomes have significantly improved alongside developments in surgical technique, peri-operative patient optimisation and post-transplantation management [1]. However, it remains a high risk procedure with significant morbidity and mortality attributable in the short term largely to surgical complications and rejection, and in the longer term to organ dysfunction and malignancy, often related to immunosuppressive medication [2,3]. Due to the challenges inherent to the surgical procedure, traditional post-operative management has been to maintain a period of clinical observation while the patient remains mechanically …


Comprehensive Measurement Of The Prevalence Of Dementia In Low- And Middle-Income Countries: Stride Methodology And Its Application In Indonesia And South Africa, Nicolas Farina, Roxanne Jacobs, Yuda Turana, Fasihah Irfani Fitri, Marguerite Schneider, Imelda Theresia, Sumaiyah Docrat, Tara Puspitarini Sani, Lydia Augustina, Emiliano Albanese, Adelina Comas-Herrera, Toit P Du, Cleusa P. Ferri, Ishtar Govia, Aliaa Ibnidris, Martin Knapp, Sube Banerjee Jan 2023

Comprehensive Measurement Of The Prevalence Of Dementia In Low- And Middle-Income Countries: Stride Methodology And Its Application In Indonesia And South Africa, Nicolas Farina, Roxanne Jacobs, Yuda Turana, Fasihah Irfani Fitri, Marguerite Schneider, Imelda Theresia, Sumaiyah Docrat, Tara Puspitarini Sani, Lydia Augustina, Emiliano Albanese, Adelina Comas-Herrera, Toit P Du, Cleusa P. Ferri, Ishtar Govia, Aliaa Ibnidris, Martin Knapp, Sube Banerjee

Peninsula Medical School

Background A core element of the Strengthening Responses to Dementia in Developing Countries (STRiDE) programme was to generate novel data on the prevalence, cost and impact of dementia in low- and middle-income countries, to build better health policy. Indonesia and South Africa are two middle-income countries in need of such data. Aims To present the STRiDE methodology and generate estimates of dementia prevalence in Indonesia and South Africa. Method We conducted community-based, single-phase, cross-sectional studies in Indonesia and South Africa, randomly sampling participants aged 65 years or older in each country. Dementia prevalence rates for each country were generated by …


How To … Define Clinical Education Research Terminology: A Glossary, Gabrielle M. Finn, Ben Charmer, Oliver E. Burton, Aqua Asif, Matthew H.V. Byrne, Nicola Brennan, Megan E.L. Brown Jan 2023

How To … Define Clinical Education Research Terminology: A Glossary, Gabrielle M. Finn, Ben Charmer, Oliver E. Burton, Aqua Asif, Matthew H.V. Byrne, Nicola Brennan, Megan E.L. Brown

Peninsula Medical School

Clinical education research (ClinEdR) utilises diverse terminology, which can lead to confusion. A common language is essential for enhancing impact. An expert panel drawn from various workstreams within the National Institute for Health and Care Research (NIHR) Incubator for Clinical Education Research was tasked with reviewing an initial list of terms for the development of a glossary of terms in the field of ClinEdR. The glossary was populated with terms, definitions and foundational papers by the authors and peer-reviewed for accuracy. The glossary of terms developed for ClinEdR should enable researchers to use a common language, promoting consistency and improving …


Guiding Principles For Effective Collaborative Implementation Strategies For Multisite Hospital Improvement Initiatives: A Mixed-Method Realist Evaluation Of Collaborative Strategies Used In Four Multisite Initiatives At Public Hospitals In New South Wales, Australia, Janet C. Long, Mitchell N. Sarkies, Emilie Francis-Auton, Natalie Roberts, Rebecca Hardwick, Hoa Mi Nguyen, Jean Frederic Levesque, Diane E. Watson, Johanna Westbrook, Peter D. Hibbert, Frances Rapport, Jeffrey Braithwaite Jan 2023

Guiding Principles For Effective Collaborative Implementation Strategies For Multisite Hospital Improvement Initiatives: A Mixed-Method Realist Evaluation Of Collaborative Strategies Used In Four Multisite Initiatives At Public Hospitals In New South Wales, Australia, Janet C. Long, Mitchell N. Sarkies, Emilie Francis-Auton, Natalie Roberts, Rebecca Hardwick, Hoa Mi Nguyen, Jean Frederic Levesque, Diane E. Watson, Johanna Westbrook, Peter D. Hibbert, Frances Rapport, Jeffrey Braithwaite

Peninsula Medical School

Objective Large-scale, multisite hospital improvement initiatives can advance high-quality care for patients. Implementation support is key to adoption of change in this context. Strategies that foster collaboration within local teams, across sites and between initiative developers and users are important. However not all implementation strategies are successful in all settings, sometimes realising poor or unintended outcomes. Our objective here is to develop guiding principles for effective collaborative implementation strategies for multi-site hospital initiatives. Design Mixed-method realist evaluation. Realist studies aim to examine the underlying theories that explain differing outcomes, identifying mechanisms and contextual factors that may trigger them. Setting We …


Modern Cemented Furlong Hemiarthroplasty: Are Dislocations Rates Better?, C. U. Menakaya, M. Shah, H. Ingoe, R. Malhotra, A. Mannan, T. Boddice, V. Allgar, S. Gopal, A. Mohsen, N. Muthukumar Jan 2023

Modern Cemented Furlong Hemiarthroplasty: Are Dislocations Rates Better?, C. U. Menakaya, M. Shah, H. Ingoe, R. Malhotra, A. Mannan, T. Boddice, V. Allgar, S. Gopal, A. Mohsen, N. Muthukumar

Peninsula Medical School

Background Dislocation following hip hemiarthroplasty is a major complication with increased mortality and morbidity. Data looking at dislocation following contemporary bipolar stems are lacking in literature. Methods Retrospective review of our prospective national hip fracture database over a two-year period. Group 1 comprised of consecutive patients receiving bipolar Furlong prosthesis (N222) while Group 2 was made up of a historical cohort (uncemented; N254). Clinical and radiological records were reviewed to determine dislocation rates, causes and associative factors of dislocations. Data were analysed using SPSS. Results Following 476 hemiarthroplasties performed during the study period, 12 (2.5%) dislocations were reported (eight in …


Transition Theory And The Emotional Journey To Medical Educator Identity: A Qualitative Interview Study, J Browne, T Collett Jan 2023

Transition Theory And The Emotional Journey To Medical Educator Identity: A Qualitative Interview Study, J Browne, T Collett

Peninsula Medical School

Background. Medical academia is in crisis, with fewer people entering and growing concern at numbers leaving. While faculty development is often seen as part of the solution, there are significant issues with faculty not engaging with and resisting development opportunities. Lack of motivation may be linked to what might be called a ‘weak’ educator identity. We studied medical educators' experiences of career development to gain further insights into: how professional identity may develop; individuals' accompanying emotional responses to perceived identity change; and consideration of the accompanying temporal dimensions. Drawing on new materialist sociology, we explore medical educator identity formation in …


Covid-19 Vaccine Effectiveness Against Hospitalisation And Death Of People In Clinical Risk Groups During The Delta Variant Period: English Primary Care Network Cohort Study, Heather J. Whitaker, Ruby S.M. Tsang, Rachel Byford, Carole Aspden, Elizabeth Button, Praveen Sebastian Pillai, Gavin Jamie, Debasish Kar, John Williams, Mary Sinnathamby, Gemma Marsden, William H. Elson, Meredith Leston, Sneha Anand, Cecilia Okusi, Xuejuan Fan, Ezra Linley, Cathy Rowe, Silvia Darcangelo, Ashley D. Otter, Joanna Ellis, F.D. Richard Hobbs, Victoria Tzortziou-Brown, Maria Zambon, Mary Ramsay, Kevin E. Brown, Gayatri Amirthalingam, Nick J. Andrews, Simon De Lusignan, Jamie Lopez Bernal Jan 2023

Covid-19 Vaccine Effectiveness Against Hospitalisation And Death Of People In Clinical Risk Groups During The Delta Variant Period: English Primary Care Network Cohort Study, Heather J. Whitaker, Ruby S.M. Tsang, Rachel Byford, Carole Aspden, Elizabeth Button, Praveen Sebastian Pillai, Gavin Jamie, Debasish Kar, John Williams, Mary Sinnathamby, Gemma Marsden, William H. Elson, Meredith Leston, Sneha Anand, Cecilia Okusi, Xuejuan Fan, Ezra Linley, Cathy Rowe, Silvia Darcangelo, Ashley D. Otter, Joanna Ellis, F.D. Richard Hobbs, Victoria Tzortziou-Brown, Maria Zambon, Mary Ramsay, Kevin E. Brown, Gayatri Amirthalingam, Nick J. Andrews, Simon De Lusignan, Jamie Lopez Bernal

Peninsula Medical School

No abstract provided.


Predictors Of Loneliness During The Covid-19 Pandemic In People With Dementia And Their Carers In England: Findings From The Determind-C19 Study, For The Determind Team, Rotem Perach, Sanna Read, Ben Hicks, Peter R. Harris, Jennifer Rusted, Carol Brayne, Margaret Dangoor, Eleanor Miles, Josie Dixon, Louise Robinson, Alan Thomas, Sube Banerjee Jan 2023

Predictors Of Loneliness During The Covid-19 Pandemic In People With Dementia And Their Carers In England: Findings From The Determind-C19 Study, For The Determind Team, Rotem Perach, Sanna Read, Ben Hicks, Peter R. Harris, Jennifer Rusted, Carol Brayne, Margaret Dangoor, Eleanor Miles, Josie Dixon, Louise Robinson, Alan Thomas, Sube Banerjee

More Faculty of Health Research

Objectives: To identify factors that predict the risk of loneliness for people with dementia and carers during a pandemic. Methods: People with dementia and their carers completed assessments before (July 2019–March 2020; 206 dyads) and after (July–October 2020) the first Covid-19 ‘lockdown’ in England. At follow-up, the analytic sample comprised 67 people with dementia and 108 carers. We built a longitudinal path model with loneliness as an observed outcome. Carer type and social contacts at both measurements were considered. Other social resources (quality of relationship, formal day activities), wellbeing (anxiety, psychological wellbeing) and cognitive impairment were measured with initial level …


The Impact Of Myosteatosis On Outcomes Following Surgery For Gastrointestinal Malignancy: A Meta-Analysis, A Maccormick, A Streeter, M Puckett, S Aroori Jan 2023

The Impact Of Myosteatosis On Outcomes Following Surgery For Gastrointestinal Malignancy: A Meta-Analysis, A Maccormick, A Streeter, M Puckett, S Aroori

Peninsula Medical School

INTRODUCTION: The aim of this review was to evaluate the impact of preoperative myosteatosis on long-term outcomes following surgery for gastrointestinal malignancy.

METHODS: We conducted a systematic search of the electronic information sources, including PubMed MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), CINAHL and AMED. Studies were included if they reported the impact of preoperatively defined myosteatosis, or a similar term, on long-term survival outcomes following surgery for gastrointestinal malignancy. A subgroup analysis was performed for those studies reporting outcomes for colorectal cancer patients only.

FINDINGS: Thirty-nine full-text articles were reviewed for inclusion, with 19 being retained after …


Evaluation Of A Complex Intervention For Prisoners With Common Mental Health Problems, Near To And After Release: The Engager Randomised Controlled Trial, Richard Byng, Tim Kirkpatrick, Charlotte Lennox, Fiona C. Warren, Rob Anderson, Sarah Louise Brand, Lynne Callaghan, Lauren Carroll, Graham Durcan, Laura Gill, Sara Goodier, Jonathan Graham, Rebecca Greer, Mark Haddad, Tirril Harris, William Henley, Rachael Hunter, Sarah Leonard, Mike Maguire, Susan Michie, Christabel Owens, Mark Pearson, Cath Quinn, Sarah Rybczynska-Bunt, Caroline Stevenson, Amy Stewart, Alex Stirzaker, Roxanne Todd, Florian Walter, Lauren Weston, Nat Wright, Rod S. Taylor, Jenny Shaw Jan 2023

Evaluation Of A Complex Intervention For Prisoners With Common Mental Health Problems, Near To And After Release: The Engager Randomised Controlled Trial, Richard Byng, Tim Kirkpatrick, Charlotte Lennox, Fiona C. Warren, Rob Anderson, Sarah Louise Brand, Lynne Callaghan, Lauren Carroll, Graham Durcan, Laura Gill, Sara Goodier, Jonathan Graham, Rebecca Greer, Mark Haddad, Tirril Harris, William Henley, Rachael Hunter, Sarah Leonard, Mike Maguire, Susan Michie, Christabel Owens, Mark Pearson, Cath Quinn, Sarah Rybczynska-Bunt, Caroline Stevenson, Amy Stewart, Alex Stirzaker, Roxanne Todd, Florian Walter, Lauren Weston, Nat Wright, Rod S. Taylor, Jenny Shaw

Peninsula Medical School

Background Many male prisoners have significant mental health problems, including anxiety and depression. High proportions struggle with homelessness and substance misuse. Aims This study aims to evaluate whether the Engager intervention improves mental health outcomes following release. Method The design is a parallel randomised superiority trial that was conducted in the North West and South West of England (ISRCTN11707331). Men serving a prison sentence of 2 years or less were individually allocated 1:1 to either the intervention (Engager plus usual care) or usual care alone. Engager included psychological and practical support in prison, on release and for 3–5 months in …


Inhibition Of Yap/Taz-Driven Tead Activity Prevents Growth Of Nf2-Null Schwannoma And Meningioma, Liyam Laraba, Lily Hillson, Julio Grimm De Guibert, Amy Hewitt, Maisie R Jaques, Tracy T Tang, Leonard Post, Emanuela Ercolano, Ganesha Rai, Shyh-Ming Yang, Daniel J Jagger, Waldemar Woznica, Philip Edwards, Aditya G Shivane, C Oliver Hanemann, David B Parkinson Jan 2023

Inhibition Of Yap/Taz-Driven Tead Activity Prevents Growth Of Nf2-Null Schwannoma And Meningioma, Liyam Laraba, Lily Hillson, Julio Grimm De Guibert, Amy Hewitt, Maisie R Jaques, Tracy T Tang, Leonard Post, Emanuela Ercolano, Ganesha Rai, Shyh-Ming Yang, Daniel J Jagger, Waldemar Woznica, Philip Edwards, Aditya G Shivane, C Oliver Hanemann, David B Parkinson

Peninsula Medical School

Schwannoma tumours typically arise on the eighth cranial nerve and are mostly caused by loss of the tumour suppressor Merlin (NF2). There are no approved chemotherapies for these tumours and the surgical removal of the tumour carries a high risk of damage to the eighth or other close cranial nerve tissue. New treatments for schwannoma and other NF2-null tumours such as meningioma are urgently required. Using a combination of human primary tumour cells and mouse models of schwannoma, we have examined the role of the Hippo signalling pathway in driving tumour cell growth. Using both genetic ablation of the Hippo …


Motivational Support Intervention To Reduce Smoking And Increase Physical Activity In Smokers Not Ready To Quit: The Tars Rct, Adrian H. Taylor, Tom P. Thompson, Adam Streeter, Jade Chynoweth, Tristan Snowsill, Wendy Ingram, Michael Ussher, Paul Aveyard, Rachael L. Murray, Tess Harris, Colin Green, Jane Horrell, Lynne Callaghan, Colin J. Greaves, Lisa Price, Lucy Cartwright, Jonny Wilks, S Campbell, Dan Preece, Siobhan Creanor Jan 2023

Motivational Support Intervention To Reduce Smoking And Increase Physical Activity In Smokers Not Ready To Quit: The Tars Rct, Adrian H. Taylor, Tom P. Thompson, Adam Streeter, Jade Chynoweth, Tristan Snowsill, Wendy Ingram, Michael Ussher, Paul Aveyard, Rachael L. Murray, Tess Harris, Colin Green, Jane Horrell, Lynne Callaghan, Colin J. Greaves, Lisa Price, Lucy Cartwright, Jonny Wilks, S Campbell, Dan Preece, Siobhan Creanor

Peninsula Medical School

No abstract provided.


Engaging Youth At Risk Of Violence In Services: Messages From Research, Nick Axford, John Tredinnick-Rowe, S Rybczynska-Bunt, Lorna Burns, Finlay Green, Tom Thompson Jan 2023

Engaging Youth At Risk Of Violence In Services: Messages From Research, Nick Axford, John Tredinnick-Rowe, S Rybczynska-Bunt, Lorna Burns, Finlay Green, Tom Thompson

Peninsula Medical School

Addressing youth violence is a public health priority given its prevalence, harms and costs to society. Services designed to prevent or reduce youth violence exist. However, their effectiveness depends on youth engaging with them. To our knowledge, there is no overview of the evidence on how to support this process. This article therefore aims to identify key messages from the scientific literature about how services can best engage youth at risk of involvement in violence. We undertook a rapid review of the evidence on youth engagement in services, prioritising English language studies published from 2010- which included youth aged 10–14 …