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2023

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Establishing A Benchmark For Opioid Consumption After Cesarean Birth, Laura Senn Jan 2023

Establishing A Benchmark For Opioid Consumption After Cesarean Birth, Laura Senn

Faculty Research, Scholarly, and Creative Activity

No abstract provided.


Gender Dynamics In The Management Care Of Internally Displaced Persons: The Boko Haram Insurgency, Evelyn Kikelomo Ikuenobe Otaigbe Jan 2023

Gender Dynamics In The Management Care Of Internally Displaced Persons: The Boko Haram Insurgency, Evelyn Kikelomo Ikuenobe Otaigbe

Walden Dissertations and Doctoral Studies

The Boko Haram asymmetric insurgency and warfare have decimated the Northeastern region of Nigeria and its neighboring environs of Chad, Niger, and Benin. The purpose of this study was to explore the peculiar socioethnic and cultural challenges encountered by female victims of Boko Haram terrorism at internally displaced persons camps in Abuja, Nigeria, including challenges in functioning, relocating, and acclimating back into society. A phenomenological approach was applied to understand participants’ lived experiences. Data collection occurred through interviews and observation. Data analysis involved the synthesis of narratives, and generation of themes. Among the emergent themes were poor feeding; lack of …


Perceptions Of Law Enforcement Officers Regarding Their Interactions With Persons In Mental Health Crises., Monica Roundtree Jan 2023

Perceptions Of Law Enforcement Officers Regarding Their Interactions With Persons In Mental Health Crises., Monica Roundtree

Walden Dissertations and Doctoral Studies

Law enforcement officers are guided by principles to protect and serve the community in general; this includes persons with mental health illnesses. These officers are often the sole community resource responding to calls involving persons in mental health crises. However, many officers lack the knowledge and skills to effectively interact with this group. This quantitative study addressed how law enforcement officers perceive that a selected policy, procedure, or strategy is effective for interacting with a person experiencing a mental health crisis. The theoretical framework for this study is the procedural justice theory. A convenience sample of 100 sworn law enforcement …


An Examination Of The Impact Of Police Chaplain Programs And Spirituality On Police Officers’ Mental Health, Samuel Protel Maxwell Jan 2023

An Examination Of The Impact Of Police Chaplain Programs And Spirituality On Police Officers’ Mental Health, Samuel Protel Maxwell

Walden Dissertations and Doctoral Studies

Spirituality has been a fundamental aspect of treating post-traumatic stress disorder (PTSD) in many officers. PTSD affects a high percentage of officers and many of whom live a highly stressful and traumatic life even outside of work. The purpose of this qualitative study was to examine the impact of police chaplain programs and spirituality on police officers' mental health. The research question asked how a police chaplain program and spirituality impacted police officers. This study's theoretical framework was Pargament's theory. Qualitative research with a narrative analysis design was chosen to collect data from semi-structured interviews. The 10 participants, including six …


Organizational Strategies And Best Practices For Telehealth Delivery During Covid-19, Maria D. Mejia Jan 2023

Organizational Strategies And Best Practices For Telehealth Delivery During Covid-19, Maria D. Mejia

Walden Dissertations and Doctoral Studies

Organizational Strategies and Best Practices for Telehealth Delivery during COVID-19


Viewpoints Of Classroom Teachers On Educational Issues Of Students With Interrupted Formal Education, Farah Merzier-Baudin Jan 2023

Viewpoints Of Classroom Teachers On Educational Issues Of Students With Interrupted Formal Education, Farah Merzier-Baudin

Walden Dissertations and Doctoral Studies

AbstractMost research on students with interrupted formal education (SIFE) and English language learners (ELLs) documents their struggle with higher attrition rates and behavioral issues in high school. This qualitative study was conducted to examine high school teachers’ perspectives working with SIFE/ELLs in the classroom. Vygotsky’s sociocultural theory (SCT) indicated that students benefit from classrooms with high social interaction among all classroom participants and appropriate scaffolding of learning materials. Although SCT and most research focused on the students’ perspectives, this research focused on teachers’ perspectives. Data were collected from semistructured, open-ended interviews with 20 participants who teach or work with SIFE/ELLs. …


Impact Of Type 2 Diabetes And Hypertension On Allocation Of Grant Funds In Federally Qualified Health Centers, Rhonda Mullins Jan 2023

Impact Of Type 2 Diabetes And Hypertension On Allocation Of Grant Funds In Federally Qualified Health Centers, Rhonda Mullins

Walden Dissertations and Doctoral Studies

Limited resources exist for managing the increasing cases of hypertension and type 2 diabetes, which underlines the need to continuously review reimbursement plans to ensure care affordability for chronic illness. The purpose of this quantitative study was to determine whether a correlation existed between the number of patients with type 2 diabetes, hypertension, and demographic characteristics (independent variables) seen at Federally Qualified Health Centers (FQHCs) and the allocation of grant funds from Health Resources and Service Administration (HRSA) (dependent variable) from 2016 – 2020 among adults 18 years old and older in the United States. Guided by the Transaction Cost …


Health Education Needs For Mortality Surveillance In Machakos County, Kenya, James S. Mwanza Jan 2023

Health Education Needs For Mortality Surveillance In Machakos County, Kenya, James S. Mwanza

Walden Dissertations and Doctoral Studies

Reporting mortality information is the primary data source from which evidence can be drawn to monitor disease trends and inform public health policy to improve population health. Still, only two-thirds of expected annual deaths are reported globally. Health education and promotion play a significant role in empowering communities to uptake public health services such as mortality surveillance. This qualitative descriptive study aimed to understand health workers’ (HWs’) perspectives regarding the need for health education to support mortality surveillance in Machakos County, Kenya. The capabilities, opportunities, and motivation for the behavior change model guided the study. Semi-structured interviews were used to …


An Association Of The Transgenerational Implications Of Redlining And Obesity On Pediatric Type Ii Diabetes, Carlin Dexter Nelson Jan 2023

An Association Of The Transgenerational Implications Of Redlining And Obesity On Pediatric Type Ii Diabetes, Carlin Dexter Nelson

Walden Dissertations and Doctoral Studies

s the prevalence and incidence of childhood obesity has increased, so has the number of cases of pediatric Type 2 diabetes mellitus (T2DM). Although made unconstitutional in 1968, the transgenerational implications of redlining can be observed in disinvestments resulting in neighborhood detraction. Utilizing the 2019–2020 National Children’s Health Survey, the purpose of the study was to evaluate the relationship between obesity, T2DM, and neighborhood detraction elements as well as assessed indicators of T2DM in non-institutionalized children 6 through17 years of age (N = 34,725). The social determinants of health perspective served as the conceptual framework for the study. Results indicated …


Educating Providers And Nurses On Human Trafficking, Valerie Smith Jan 2023

Educating Providers And Nurses On Human Trafficking, Valerie Smith

Walden Dissertations and Doctoral Studies

Human trafficking is a global public health problem. Victims of human trafficking experience higher rates of sexually transmitted diseases, reproductive damage, sexual violence, infertility, and mental and behavioral issues. To help end human trafficking, which is potentially deadly, raising awareness about this topic is essential for victim survival. A gap in practice among staff at a community health center regarding recognition of victims of human trafficking and procedures for potential victims was identified. An education program focused on increasing knowledge and awareness was developed to close this gap. Guided by Watson’s theory of human caring, a 30-minute educational session followed …


Perceptions Of Teachers In A Private Residential Juvenile Treatment Facility, Douglas E. Stevenson Jan 2023

Perceptions Of Teachers In A Private Residential Juvenile Treatment Facility, Douglas E. Stevenson

Walden Dissertations and Doctoral Studies

AbstractThe problem for this study was the lack of research about what teachers consider to be the successes, the risks, and the potential dangers of working in a school prison setting. The purpose of this qualitative study was to investigate teacher perceptions about successes, risks, and potential dangers of teaching in a prison school setting. This research study was guided by Deci and Ryan’s self-determination theory, which presents a framework for the study of human motivation and personality. The research question examined teachers’ perspectives about the successes, the risks, and dangers of working in a private residential juvenile treatment facility. …


Exploring Educators' Perception Of Remote Instructional Collaboration In Liberian Higher Education Classrooms, George Wah Williams Jan 2023

Exploring Educators' Perception Of Remote Instructional Collaboration In Liberian Higher Education Classrooms, George Wah Williams

Walden Dissertations and Doctoral Studies

Public higher education institutions in Liberia have employed various mitigating measures to improve instruction quality and increase learning outcomes; however, little was known about remote instructional collaboration as a strategic approach in Liberian higher education classrooms. This qualitative study, based on Everett Rogers’ Diffusion of Innovation theory, explored the Liberian educators’ perceptions of and disposition to RIC in public tertiary classrooms in Liberia. Seeking Liberian educators’ perception of and disposition to remote instructional collaboration in public tertiary classrooms drove this investigation. Two groups of 17 educators based in the United States and Liberia were interviewed using a semi-structured protocol facilitated …


African American Men’S Lived Experiences Of Stigma Regarding Use Of Mental Health Services, Leon M. Wilson Jan 2023

African American Men’S Lived Experiences Of Stigma Regarding Use Of Mental Health Services, Leon M. Wilson

Walden Dissertations and Doctoral Studies

AbstractAfrican American men are disproportionately more likely to live with untreated mental health challenges; the incidence of mental illness in African Americans is, per capita, 30% higher than among non-Hispanic Whites. African American men experience significant barriers and deterrents to psychological help seeking, which are primarily due to internalized stigma. The purpose of this qualitative phenomenological study was to explore and describe African American men’s experiences that influenced internalized stigma regarding seeking and using traditional mental health services. The theoretical framework included the theory of social stigma and minority stress theory. Nine purposively selected African American men from the Mid-Atlantic …


Employees’ Engagement Experiences In Private-Sector Companies In Urban Jamaica, Colleen Rose-Marie Bancroft Jan 2023

Employees’ Engagement Experiences In Private-Sector Companies In Urban Jamaica, Colleen Rose-Marie Bancroft

Walden Dissertations and Doctoral Studies

Marginal and fluctuating employee engagement levels continue to be a concern among organizations, evidenced by the quest for dynamic solutions and the investigative work observed in the literature. The purpose of this study was to understand the meaning of engagement for employees working in two urban, private-sector companies in Jamaica. A qualitative approach, with a hermeneutic phenomenological design was used to complete the study using the lens of self-efficacy theory. Semistructured interviews were conducted via Zoom with 12 employees and their engagement experiences were analyzed. The results indicate that organizational systems, working conditions, and shared values (organizational and national culture) …


Identifying And Examining Key Themes Emanating From The U.S. Legislative Tobacco Policy Subsystem, Arnon Dayak Jan 2023

Identifying And Examining Key Themes Emanating From The U.S. Legislative Tobacco Policy Subsystem, Arnon Dayak

Walden Dissertations and Doctoral Studies

Americans’ continuously increasing tobacco use in the form of smoking presents an ongoing and rising negative health impact on this leading cause of preventable death. Despite existing U.S. federal level tobacco regulation through the Family Smoking Prevention and Tobacco Control Act (FSPTCA), U.S. tobacco use remains ubiquitous demonstrating existent ineffectiveness of tobacco control legislation. Unknown underlying attributing factors present critical information gaps which, when exposed, could improve tobacco regulation. Using a case study approach, the question, “What key themes are aligned with legislative subsystem actors when voting on the FSPTCA” was examined. Multi-source data streams using existing secondary datasets including …


Relationship Between An Entrepreneur’S Self-Efficacy, Self-Leadership, And Startup Sustainability In Nigeria, Juliet Ehimuan Jan 2023

Relationship Between An Entrepreneur’S Self-Efficacy, Self-Leadership, And Startup Sustainability In Nigeria, Juliet Ehimuan

Walden Dissertations and Doctoral Studies

Self-efficacy and self-leadership have been identified as important indicators of business sustainability. Business owners and investors are concerned about sustainability because most businesses fail within the first five years. Grounded in self-efficacy and self-leadership theories, the purpose of this quantitative correlation study was to examine the relationship between entrepreneurial self-efficacy, self-leadership and startup sustainability. The participants were 156 entrepreneurs who completed the entrepreneurial self-efficacy scale and the abbreviated self-leadership questionnaire delivered via email. The multiple linear regression analysis results indicated the model was able to significantly predict startup sustainability, F(2, 129) = 432.47, p < .001, R2 = .87. Self-efficacy provided a significant contribution to the model (t = 8.424, p = < .001, β = .914). In contrast, the contribution of self-leadership was not significant (t = 0.185, p = .853, β = .20). A key recommendation is the utilization of mentoring programs and structured leadership internships that enhance self-efficacy by providing startup leaders with exposure to more seasoned corporate leaders, and successful peers who have had similar experiences to theirs. The implications for positive social change include the potential development of training and capacity-building programs that can be provided to entrepreneurs and other startup leaders to enhance their ability to sustain their startups, leading to more successful businesses, job creation, and economic growth.


Stressors And Depression Among Adolescents With Co-Rumination As A Moderator, Angela Grosso-Burke Jan 2023

Stressors And Depression Among Adolescents With Co-Rumination As A Moderator, Angela Grosso-Burke

Walden Dissertations and Doctoral Studies

Stress, depression, and co-rumination have been a focus of scholars in recent years. Although studies have considered the relationship among stressors, depression, and co-rumination, little is known about the moderating effects of co-rumination. This study aimed to address the gap in the literature by examining moderating effects of co-rumination on relations between stressors and depression, along with further moderating effects of sex, race, and grade. The current study examined mean-level race, sex, and grade differences in the relation among stressors (total, family, peer, physical appearance, sport/physical activity, school) and depressive symptoms in adolescents. Analyses were conducted to determine the relationship …


Occupational Burnout Factors Among Correctional Mental Health Providers, Morgan Gruhot Jan 2023

Occupational Burnout Factors Among Correctional Mental Health Providers, Morgan Gruhot

Walden Dissertations and Doctoral Studies

Burnout rates of correctional employees are higher than employees in the general public. The purpose of this study was to identify how occupational factors impact burnout rates among correctional mental health workers. Grounded in the job-demands theoretical model, this study compared burnout rates among mental health staff within county jails and state prisons. Burnout was measured using the Maslach Burnout Inventory and Occupational factors were measured using the Areas of Work life Survey and Pandemic Experience and Perception Survey. Data was analyzed using IBM SSPS software to address multiple a priori directional research questions. Research questions considered how occupational factors …


Filipino Americans’ Attitudes And Experiences With Mental Health And Help-Seeking Behaviors, Kelsey Guerrero Jan 2023

Filipino Americans’ Attitudes And Experiences With Mental Health And Help-Seeking Behaviors, Kelsey Guerrero

Walden Dissertations and Doctoral Studies

Filipino Americans suffer from mental illness at an alarming rate and have a low rate of seeking mental health treatment. Because Filipino Americans are underrepresented in social science research, psychologists do not understand how to resolve this issue within the Filipino American population. The purpose of this generic qualitative study was to describe the experiences with mental health and treatment of Filipino Americans. Bronfenbrenner’s ecological model theory and Latane’s social impact theory served as the theoretical foundation for the study. A sample of 12 Filipino Americans was interviewed using a semistructured interview design. Participants were asked 10 questions addressing their …


The Relationship Between College Credits Earned In A Community College Dual Enrollment Program And First-Year Grade Point Average, Johnesa Hodge Jan 2023

The Relationship Between College Credits Earned In A Community College Dual Enrollment Program And First-Year Grade Point Average, Johnesa Hodge

Walden Dissertations and Doctoral Studies

The increased number of college credits earned in dual enrollment programs initiated concern by educators, researchers, and policymakers regarding college readiness. However, data are scarce and inconsistent across governing states and community colleges to measure college readiness and dual enrollment’s effectiveness. The purpose of this quantitative study examined early college credits earned in general education, career and technical education, college orientation disciplines, and first-year grade point average (GPA) to measure college readiness. Conley’s key dimensions of college and career readiness model grounded the study. Archival transcript data were collected from a Michigan community college for 524 former dual enrollment students. …


Human Services Professionals' Perspectives On U.S. Homeless Veterans' Access To Social Services During The Covid-19 Pandemic, Kemnesia Hobbs Jan 2023

Human Services Professionals' Perspectives On U.S. Homeless Veterans' Access To Social Services During The Covid-19 Pandemic, Kemnesia Hobbs

Walden Dissertations and Doctoral Studies

AbstractAmerican veterans who are homeless can face significant challenges accessing social services, and these challenges were further exacerbated during the COVID-19 pandemic. The purpose of this study was to explore the experiences of homeless veterans in seeking services during the COVID-19 pandemic through the perspectives of the human services professionals (HSPs) who provide support to veterans in the areas of mental health, housing, addiction, and food security. The first research question concerned HSPs' perceptions and interpretations of the strategies and barriers for homeless veterans in accessing services during COVID-19. The second research question addressed whether HSPs observed posttraumatic growth in …


The Lived Experiences Of Minority Widowers With Dependent Children, Cathy-Ann L. King Jan 2023

The Lived Experiences Of Minority Widowers With Dependent Children, Cathy-Ann L. King

Walden Dissertations and Doctoral Studies

Spousal death is a traumatic event well documented amongst clinical professionals because of its impact on a man’s physical and mental health. However, prior research on widowers has focused predominantly on white middle-class males. Little is known about the black indigenous people of color (BIPOC) male experience with spousal death, especially from those who are raising their dependent children. This qualitative phenomenological study aimed to understand the lived experiences of BIPOC male widowers and their children. BIPOC widowers experiencing the trauma of this life-changing event without professional assistance are at higher risk of emotional, physical, and mental distress. Attachment theory …


Occupational Risk Perceptions Among Foreign-Born Construction Workers In Central Florida, Matthew Edison Law Jan 2023

Occupational Risk Perceptions Among Foreign-Born Construction Workers In Central Florida, Matthew Edison Law

Walden Dissertations and Doctoral Studies

Hispanic and Latino foreign-born construction workers in the United States experience higher rates of serious injuries and fatalities in the workplace than their native-born peers. Previous research has pointed to specific vulnerabilities among this population, including birthplace, age of the worker, language barriers, and education level, but little to no research has examined addressable risk factors, such as occupational risk perceptions, among this population. The purpose of this quantitative study was to determine the relationship between birthplace, number of years working in the United States, and occupational risk perceptions while controlling for age of the worker, language barriers, and education …


Puerto Rican Retired Teachers’ Perceptions About Their Financial Sufficiency, Rossana López León Jan 2023

Puerto Rican Retired Teachers’ Perceptions About Their Financial Sufficiency, Rossana López León

Walden Dissertations and Doctoral Studies

In Puerto Rico, the Teachers’ Retirement System, which has a membership of around 36,000 retired public-school teachers, is currently facing major restructuring and budget cuts, as part of a larger restructuring of all government agencies to meet the economic emergency they were facing. The recent retirement system reforms were focused mainly on cutting benefits, such as medications, Christmas and summer bonuses, and the cost-of-living adjustment. The purpose of this study was to explore the perceptions of retired teachers regarding their financial sufficiency, and to identify their attitudes, beliefs, and opinions/feelings in light of their socioeconomic profile. The research question focused …


Criminology And Violent Extremist Radicalization, Starlett Michele Martin Jan 2023

Criminology And Violent Extremist Radicalization, Starlett Michele Martin

Walden Dissertations and Doctoral Studies

After the 9/11 terrorist attacks, research on foreign terrorism became extensive in the United States while research on domestic terrorism and violent extremist radicalization was lacking. Despite the research that has been done, there was a lapse in scholarship analyzing terrorism radicalization and its relationship with criminology. The purpose of this general qualitative study was to analyze the perceptions of experts in terrorism and criminology about how factors of criminology can explain violent extremist radicalization. This study used two conceptual models of terrorism radicalization: (a) the staircase to terrorism and the (b) 4-stage model of the terrorist mindset. In addition, …


Locus Of Control, Mindfulness, And Perceived Caregiver Burden In Informal Caregivers Of People With Dementia, Tiffany Marinos-Sterge Jan 2023

Locus Of Control, Mindfulness, And Perceived Caregiver Burden In Informal Caregivers Of People With Dementia, Tiffany Marinos-Sterge

Walden Dissertations and Doctoral Studies

AbstractAdult informal caregivers play an essential role in the care of people with dementia living in the community. Adult informal caregivers may experience a host of negative psychological, emotional, and physical effects because of their roles as caregivers. The purpose of this quantitative correlational study was to investigate the influence of locus of control and mindfulness on the perceived caregiver burden experienced by adult informal caregivers of people with dementia, controlling for relevant sociodemographic characteristics. Social determination theory and social learning theory provided the theoretical foundation for this study. Variables were measured using the Caregiver Burden Inventory, Mindfulness Attention Awareness …


Quantifying The Implementation And Cost Of A Multisite Antibiotic Stewardship Intervention For Asymptomatic Bacteriuria, Eva Amenta, Larissa Grigoryan, Suja S Rajan, David Ramsey, Jennifer R Kramer, Annette Walder, Andrew Chou, John N Van, Sarah L Krein, Sylvia Hysong, Aanand D Naik, Barbara W Trautner Jan 2023

Quantifying The Implementation And Cost Of A Multisite Antibiotic Stewardship Intervention For Asymptomatic Bacteriuria, Eva Amenta, Larissa Grigoryan, Suja S Rajan, David Ramsey, Jennifer R Kramer, Annette Walder, Andrew Chou, John N Van, Sarah L Krein, Sylvia Hysong, Aanand D Naik, Barbara W Trautner

Faculty, Staff and Student Publications

OBJECTIVE: The intensity of an antibiotic stewardship intervention to achieve clinical impact is not known. We conducted a multisite dissemination project of an intervention to reduce treatment of asymptomatic bacteriuria (ASB) and studied: (1) the association between implementation metrics and clinical outcomes and (2) the cost of implementation.

DESIGN/SETTING/PARTICIPANTS: A central site facilitated a multimodality intervention to decrease unnecessary urine cultures and antibiotic treatment in patients with ASB at 4 Veterans Affairs medical centers.

METHODS: The intervention consisted of a decision support aid algorithm and interactive teaching cases that provided in the moment audit and feedback on how to manage …


Wastewater Pandemic Preparedness: Toward An End-To-End Pathogen Monitoring Program, Justin R Clark, Austen Terwilliger, Vasanthi Avadhanula, Michael Tisza, Juwan Cormier, Sara Javornik-Cregeen, Matthew Clayton Ross, Kristi Louise Hoffman, Catherine Troisi, Blake Hanson, Joseph Petrosino, John Balliew, Pedro A Piedra, Janelle Rios, Jennifer Deegan, Cici Bauer, Fuqing Wu, Kristina D Mena, Eric Boerwinkle, Anthony W Maresso Jan 2023

Wastewater Pandemic Preparedness: Toward An End-To-End Pathogen Monitoring Program, Justin R Clark, Austen Terwilliger, Vasanthi Avadhanula, Michael Tisza, Juwan Cormier, Sara Javornik-Cregeen, Matthew Clayton Ross, Kristi Louise Hoffman, Catherine Troisi, Blake Hanson, Joseph Petrosino, John Balliew, Pedro A Piedra, Janelle Rios, Jennifer Deegan, Cici Bauer, Fuqing Wu, Kristina D Mena, Eric Boerwinkle, Anthony W Maresso

Faculty, Staff and Student Publications

Molecular analysis of public wastewater has great potential as a harbinger for community health and health threats. Long-used to monitor the presence of enteric viruses, in particular polio, recent successes of wastewater as a reliable lead indicator for trends in SARS-CoV-2 levels and hospital admissions has generated optimism and emerging evidence that similar science can be applied to other pathogens of pandemic potential (PPPs), especially respiratory viruses and their variants of concern (VOC). However, there are substantial challenges associated with implementation of this ideal, namely that multiple and distinct fields of inquiry must be bridged and coordinated. These include engineering, …


Tnik Regulation Of Interferon Signaling And Endothelial Cell Response To Virus Infection, Khanh M Chau, Abishai Dominic, Eleanor L Davis, Sivareddy Kotla, Estefani Turcios Berrios, Arsany Fahim, Ashwin Arunesh, Shengyu Li, Dongyu Zhao, Kaifu Chen, Alan R Davis, Minh T H Nguyen, Yongxing Wang, Scott E Evans, Guangyu Wang, John P Cooke, Jun-Ichi Abe, David P Huston, Nhat-Tu Le Jan 2023

Tnik Regulation Of Interferon Signaling And Endothelial Cell Response To Virus Infection, Khanh M Chau, Abishai Dominic, Eleanor L Davis, Sivareddy Kotla, Estefani Turcios Berrios, Arsany Fahim, Ashwin Arunesh, Shengyu Li, Dongyu Zhao, Kaifu Chen, Alan R Davis, Minh T H Nguyen, Yongxing Wang, Scott E Evans, Guangyu Wang, John P Cooke, Jun-Ichi Abe, David P Huston, Nhat-Tu Le

Faculty, Staff and Student Publications

BACKGROUND: Traf2 and Nck-interacting kinase (TNIK) is known for its regulatory role in various processes within cancer cells. However, its role within endothelial cells (ECs) has remained relatively unexplored.

METHODS: Leveraging RNA-seq data and Ingenuity Pathway Analysis (IPA), we probed the potential impact of TNIK depletion on ECs.

RESULTS: Examination of RNA-seq data uncovered more than 450 Differentially Expressed Genes (DEGs) in TNIK-depleted ECs, displaying a fold change exceeding 2 with a false discovery rate (FDR) below 0.05. IPA analysis unveiled that TNIK depletion leads to the inhibition of the interferon (IFN) pathway [-log (

SUMMARY: Our findings suggest that …


Development Of Competency-Based Online Genomic Medicine Training (Cogent), Susanne B Haga, Wendy K Chung, Luis A Cubano, Timothy B Curry, Philip E Empey, Geoffrey S Ginsburg, Kara Mangold, Christina Y Miyake, Siddharth K Prakash, Laura B Ramsey, Robb Rowley, Carolyn R Rohrer Vitek, Todd C Skaar, Julia Wynn, Teri A Manolio Jan 2023

Development Of Competency-Based Online Genomic Medicine Training (Cogent), Susanne B Haga, Wendy K Chung, Luis A Cubano, Timothy B Curry, Philip E Empey, Geoffrey S Ginsburg, Kara Mangold, Christina Y Miyake, Siddharth K Prakash, Laura B Ramsey, Robb Rowley, Carolyn R Rohrer Vitek, Todd C Skaar, Julia Wynn, Teri A Manolio

Faculty, Staff and Student Publications

The fields of genetics and genomics have greatly expanded across medicine through the development of new technologies that have revealed genetic contributions to a wide array of traits and diseases. Thus, the development of widely available educational resources for all healthcare providers is essential to ensure the timely and appropriate utilization of genetics and genomics patient care. In 2020, the National Human Genome Research Institute released a call for new proposals to develop accessible, sustainable online education for health providers. This paper describes the efforts of the six teams awarded to reach the goal of providing genetic and genomic training …