Digital Commons Network^™

A Just Transition For Collie That Leaves No One Behind: A Community-Led Social Justice Analysis Of Collie’S Transition, Naomi Joy Godden, Georgia Beardman, Mehran Nejati, Evonne Scott, Jaime Yallup Farrant, Leonie Scoffern, Joseph Northover, James Khan, Lynette Winmar, Phillip Ugle, Kiera Mulholland, Jayla Parkin, Stevie Anderson, Angus Morrison-Saunders

Research outputs 2022 to 2026

No abstract provided.

Clinical Practice Guidelines On Hemochromatosis: Asian Pacific Association For The Study Of The Liver, Darrell H. G. Crawford, Grant A. Ramm, Kim R. Bridle, Amanda J. Nicoll, Martin B. Delatycki, John K. Olynyk

Research outputs 2022 to 2026

Hereditary hemochromatosis is the result of pathogenic variants in multiple genes that can result in increased body iron stores with excess iron deposited in various organs, including the liver, pancreas, and heart. The two most important advances in the field over the past 30 years have been the identification of the HFE gene (and the associated p.Cys282Tyr substitution), and the discovery of the hormone hepcidin, which is inappropriately low in this condition and is the pathophysiological basis of the increased iron absorption. The identification of mutations in the HFE gene and subsequent studies have reshaped diagnostic algorithms resulting in a …

A Systematic Literature Review Of Between-Class Ability Grouping In Australia: Enduring Tensions, New Directions, Olivia Johnston, Becky Taylor

Research outputs 2022 to 2026

Ability grouping of students into separate classes within a school can be called ‘between-class ability grouping’. This practice has persisted in Australia despite evidence that it is socially inequitable and does not improve academic outcomes. A systematic review of peer-reviewed literature about between-class ability grouping in Australia from 2012-2022 reveals only N=28 papers that meet the inclusion criteria. These papers are critiqued and synthesised into four main findings that characterise Australian research about between-class ability grouping from 2012-2022. The findings reveal a lack of substantive inquiry with most studies having limited scope and drawing on outdated or overly generalised data. …

An Updated Systematic Review Of Stroke Clinical Practice Guidelines To Inform Aphasia Management, Bridget Burton, Megan Isaacs, Emily Brogan, Kirstine Shrubsole, Monique F. Kilkenny, Emma Power, Erin Godecke, Dominique A. Cadilhac, David Copland, Sarah J. Wallace

Research outputs 2022 to 2026

Background: Aphasia is a common consequence of stroke, and people who live with this condition experience poor outcomes. Adherence to clinical practice guidelines can promote high-quality service delivery and optimize patient outcomes. However, there are currently no high-quality guidelines specific to post-stroke aphasia management. Aims: To identify and evaluate recommendations from high-quality stroke guidelines that can inform aphasia management. Summary of review: We conducted an updated systematic review in accordance with PRISMA guidelines to identify high-quality clinical guidelines published between January 2015 and October 2022. Primary searches were performed using electronic databases: PubMed, EMBASE, CINAHL, and Web of Science. Gray …

Student Motivations, Perceptions And Opinions Of Participating In Student Evaluation Of Teaching Surveys: A Scoping Review, Daniel Sullivan, Richard Lakeman, Debbie Massey, Dima Nasrawi, Marion Tower, Megan Lee

Research outputs 2022 to 2026

Several times each year the teaching performance of academics at higher education institutions are evaluated through anonymous, online student evaluation of teaching (SET) surveys. Universities use SETs to inform decisions about staff promotion and tenure, but low student participation levels make the surveys impractical for this use. This scoping review aims to explore student motivations, perceptions and opinions of SET survey completion. Five EBSCO® databases were searched using key words. Thematic analysis of a meta-synthesis of qualitative findings derived from 21 papers identified five themes: (i) the value students’ place on SET, (ii) the knowledge that SET responses are acted …

North-Central Nigerian Women’S Experiences Of Obstetric Fistula Risk Factors And Their Perceived Treatment Services: An Interpretive Description, Lydia Babatunde Bulndi, Sara J. Bayes, Esther A. Adama, Deborah M. Ireson

Research outputs 2022 to 2026

Background

An obstetric fistula also known as vesico vaginal fistula (VVF), or recto-vaginal fistula (RVF) is an abnormal opening between the urogenital tract and intestinal tract caused by prolonged obstructed labour; when the head of the baby presses on the soft tissues in the pelvis leading to loss of blood flow to the women’s bladder, vagina, and rectum. This can cause necrosis of the soft tissues resulting in debilitating fistula formations.

Aim

This study aimed to uncover North-central Nigerian women’s experiences of obstetric fistula and their perceived treatment services.

Design

Qualitative, interpretive descriptive methodology underpinned by symbolic interactionism involving face-to-face …

“A Source Of Empowerment And Well-Being”: Experiences Of A Dance And Yoga Intervention For Young Girls With Functional Abdominal Pain Disorders, Sofie Högström, Mats Eriksson, Evalotte Mörelius, Anna Duberg

Research outputs 2022 to 2026

Background: Functional abdominal pain disorders are common among children and adolescents worldwide and effective treatments are needed to alleviate suffering for these children and their families. This study aimed to explore the experience of participating in a combined dance and yoga intervention from the perspectives of girls aged 9–13 years with functional abdominal pain disorders. Materials and Methods: A randomized controlled trial called Just in TIME (Try, Identify, Move and Enjoy) recruited 121 girls aged 9–13 years with functional abdominal pain disorders. The eight-month intervention combined dance and yoga twice a week, focusing on enjoyment, socialization and playful creativity in …

Assessing Children To Identify Developmental Coordination Disorder: A Survey Of Occupational Therapists In Australia, Jacqui Hunt, Jill Zwicker, Erin Godecke, Annette Raynor

Research outputs 2022 to 2026

Background: Developmental coordination disorder (DCD), a prevalent neurodevelopmental disorder with motor and psychosocial consequences, can significantly impact children's quality of life. In Australia, most children with diagnosed/suspected DCD have received occupational therapy services, more so than any other health service. As such, occupational therapists are key in identification and treatment and require a sound knowledge of diagnostic criteria and the best evidence for practice. This study explored current occupational therapy services for children with DCD. Areas for development are identified to improve the identification of, and subsequent intervention for, children with DCD. Methods: In this cross-sectional study, an online survey …

Feasibility Of Supervised Telehealth Exercise For Patients With Advanced Melanoma Receiving Checkpoint Inhibitor Therapy, Brendan J. Crosby, Robert U. Newton, Daniel A. Galvão, Dennis R. Taaffe, Pedro Lopez Da Cruz, Tarek M. Meniawy, Muhammad A. Khattak, Wei-Sen Lam, Elin S. Gray, Favil Singh

Research outputs 2022 to 2026

Purpose: To determine the feasibility, safety and preliminary efficacy of a telehealth supervised exercise programme in patients with advanced melanoma receiving checkpoint inhibitor therapy. Methods: A 8-week non-randomised feasibility pilot trial utilising a telehealth delivered multimodal exercise programme undertaken thrice weekly with assessments at baseline and post-intervention. The study was considered feasible if there were no severe or life-threatening adverse events as a result of exercise, and three or more of the following criteria were met: the recruitment rate was > 50%, completion rate was > 80%, median programme attendance was > 75%, median exercise compliance > 75%, and average tolerance was > 70%. Preliminary …

Profiling Ambivalence In The Context Of Nonsuicidal Self-Injury, Nicole Gray, Hannah Uren, Ethan James Pemberton, Mark Boyes

Research outputs 2022 to 2026

Background: We aimed to identify profiles of ambivalence among individuals with a history of non-suicidal self-injury (NSSI) and tested whether profiles differed across various theoretically informed constructs: NSSI-related characteristics, cognitive (outcome expectancies, self-efficacy to resist NSSI), emotional (psychological distress, difficulties in emotion regulation), personality, and incentives to engage/not engage in NSSI. Methods: Individuals with a lifetime history of NSSI (n = 224) reported the extent to which they wanted to and did not want to engage in NSSI and completed well-validated measures of the constructs of interest. Results: Latent profile analysis indicated four ambivalence profiles (avoid: n = 39; moderately …

Protective Indigenous Collective Value Of Ubuntu And Child Neglect: Implications For Rural Child Protection Practice, Alhassan Abdullah, Hajara Bentum, Margarita Frederico, Felix Mensah, Lucy P. Jordan, Clifton R. Emery

Research outputs 2022 to 2026

Theories on collective efficacy and social support suggest that indigenous values that support collective practices and sanction community obligations to childcare would be protective against child neglect. Likewise, new qualitative findings show that collective values are stronger in rural areas than in urban. This study tested the claims that the value of Ubuntu, which is a symbolic cultural value of ‘being for others’, will be protective against the likelihood of neglect; this relationship will be stronger in rural compared with urban communities in Ghana. Using data obtained from a nationally representative sample of 1100 mothers (from 22 communities) in Ghana, …

Structured Dialogue State Management For Task-Oriented Dialogue Systems, Anh Duong Trinh

Doctoral

Human-machine conversational agents have developed at a rapid pace in recent years, bolstered through the application of advanced technologies such as deep learning. Today, dialogue systems are useful in assisting users in various activities, especially task-oriented dialogue systems in specific dialogue domains. However, they continue to be limited in many ways. Arguably the biggest challenge lies in the complexity of natural language and interpersonal communication, and the lack of human context and knowledge available to these systems. This leads to the question of whether dialogue systems, and in particular task-oriented dialogue systems, can be enhanced to leverage various language properties. …

Towards The Development Of A Balanced Legislative Framework For Consumer Data Protection In Electronic Commerce: The Case Of The Sultanate Of Oman, Talib Al Kharusi

Doctoral

This research aims to investigate whether the law as it currently stands in Oman provides adequate legal protection for personal data, to determine the current obstacles facing the electronic commerce sector, and to identify ways of overcoming such challenges. The empirical focus of this study will be electronic commerce transactions between companies and consumers. In this regard, the research will explore the perceptions of the main stakeholders towards privacy regulation and what implications these have for the growth of electronic commerce in Oman. The privacy that this research aims to explore is a complex issue since it concerns human feelings …

Novel Therapeutic Approaches To Treat Brain Cancer Combining 3d Cell Culture Models, Cold Atmospheric Plasma And Airborne Acoustic, Janith Wanigasekara

Doctoral

Glioblastoma (GBM), an adult-type diffuse grade 4 glioma (IDH wild type), is the most prevalent, aggressive, fatal, highly vascularized, malignant primary brain tumour in adults with a poor prognosis. Despite existing therapies such as surgical resection, radiation therapy and chemotherapy such as temozolomide (TMZ), patient survival remains largely unchanged over the last three decades. There is an urgent need for novel and effective therapeutic strategies that can overcome drug resistance, cross the blood brain barrier, and minimise off-target side effects that can negatively impact a patient's quality of life. The high failure rate of clinical trials is due to inefficient …

A Qualitative Functional Analysis Of Academic Procrastination Among Irish Undergraduate Students, Gráinne Carthy

Masters

Academic procrastination involves the needless postponement of academic tasks at the expense of one’s academic goals. Informed by the principles of Acceptance Commitment Therapy, this study explored students’ experiences of academic procrastination in an Irish undergraduate sample. Over two studies, semi structured interviews were used to explore the common scenarios in which students tended to procrastinate, and also the scenarios which by contrast tended to motivate relatively immediate academic engagement. Study 1 involved interviewing twelve participants who had been recruited from online lectures. After noting the potential for self-selection bias in this recruitment strategy, study 2 specifically recruited seven participants …

An Exploration Of Practitioners’ Experiences Of Delivering Digital Social Care Interventions To Children And Families During The Covid-19 Pandemic: Mixed Methods Study, Grainne Hickey, Claire Dunne, Lauren Maguire, Niamh Mccarthy

Articles

Digital technology is an increasingly prominent feature of health care delivery; however, social care has remained less digitized than other systems [1]. As an allied health profession, child and family social care practice is aimed at supporting the welfare and safety of vulnerable children and families. Similar to many other health professionals, social care practitioners develop an understanding of clients’ needs and provide support through the development of interpersonal relationships [2]. Traditionally, this involves physical proximity and face-to-face interaction, often in the context of the home environment [3]. Digital technologies, however, have crept into the delivery of social care interventions …

Silver(I) 1,10-Phenanthroline Complexes Are Active Against Fonsecaea Pedrosoi Viability And Negatively Modulate Its Potential Virulence Attributes, Ingrid S. Sousa Ingrid S. Sousa, Tatiana D.P. Vieira, Rubem F. S. Menna-Barreto, Allan J. Guimarães, Pauraic Mccarron, Malachy Mccann, Michael Devereux, André L. S. Santos, Lucimar F. Kneipp

Articles

The genus Fonsecaea is one of the etiological agents of chromoblastomycosis (CBM), a chronic subcutaneous disease that is difficult to treat. This work aimed to evaluate the effects of copper(II), manganese(II) and silver(I) complexes coordinated with 1,10-phenanthroline (phen)/1,10- phenanthroline-5,6-dione (phendione) on Fonsecaea spp. Our results revealed that most of these complexes were able to inhibit F. pedrosoi, F. monophora and F. nubica conidial viability with minimum inhibitory concentration (MIC) values ranging from 0.6 to 100 M. The most effective complexes against F. pedrosoi planktonic conidial cells, the main etiologic agent of CBM, were [Ag(phen)2]ClO4 and [Ag2(3,6,9-tdda)(phen)4].EtOH, (tdda: 3,6,9-trioxaundecanedioate), displaying MIC …

Synthesis, Characterisation, And Solution Behaviour Of Ag(I) Bis(Phenanthroline‑Oxazine) Complexes And The Evaluation Of Their Biological Activity Against The Pathogenic Yeast Candida Albicans, Clara Evans, Muhib Ahmed, Malachy Mccann, Kevin Kavanagh, Michael Devereux, Denise Rooney Denise Rooney, Frances Heaney

Articles

Three Ag(I) bis(phenanthroline-oxazine) complexes with varying lipophilicity were synthesised and characterised. The solution stoichiometry of 1:2 Ag(I):ligand was determined for each complex by the continuous variation Job's plot method using NMR spectroscopy. NMR studies were also carried out to investigate the fluxional behaviour of the Ag(I) complexes in solution. The biological activity of the silver(I) complexes and the corresponding ligands towards a clinical strain of Candida albicans MEN was studied using broth microdilution assays. Testing showed the choice of media and the duration of incubation were key determinants of the inhibitory behaviour towards Candida albicans, however, the difference between freshly …

Hospital Outcomes In Patients Hospitalized For Covid-19 Pneumonia: The Effect Of Sars-Cov-2 Vaccination And Vitamin D Status, Martyna Sanecka, Modar Youssef, Mohammad Abdulsalam, Syed F. Raza, Abdul Qadeer, Julia Ioana, Alya Aldoresi, Syed I. Shah, Abdul Al Lawati, Joseph Feely, William P. Tormey, Eoghan O'Neill, Liam J. Cormican, Eoin P. Judge, Daniel Mccartney, John L. Faul

Articles

SARS-CoV-2 vaccination promises to improve outcomes for patients with COVID-19 pneumonia (most notably those with advanced age and at high risk for severe disease). Here, we examine serum 25-Hydroxyvitamin D (25(OH)D) status and outcomes in both old (>70 years) and young vaccinated (n = 80) and unvaccinated (n = 91) subjects, who were hospitalized due to COVID- 19 pneumonia in a single center (Connolly Hospital Dublin). Outcomes included ICU admission and mortality. Serum 25(OH)D levels were categorized as D30 (/L), D40 (30–49.99 nmol/L) and D50 (50 nmol/L). In multivariate analyses, D30 was independently associated with ICU admission (OR: 6.87 …

Peptidases Are Potential Targets Of Copper(Ii)-1,10-Phenanthroline-5,6-Dione Complex, A Promising And Potent New Drug Against Trichomonas Vaginalis, Graziela Vargas Rigo, Fernando Gomes Cardoso, Matheus Menonca Pereira, Michael Devereux, Malachy Mccann, Andre L.S. Santos, Tiana Tasca

Articles

Trichomonas vaginalis is responsible for 156 million new cases per year worldwide. When present asymptomatically, the parasite can lead to serious complications, such as development of cervical and prostate cancer. As infection increases the acquisition and transmission of HIV, the control of trichomoniasis represents an important niche for the discovery and development of new antiparasitic molecules. This urogenital parasite synthesizes several molecules that allow the establishment and pathogenesis of infection. Among them, peptidases occupy key roles as virulence factors, and the inhibition of these enzymes has become an important mechanism for modulating pathogenesis. Based on these premises, our group recently …

Structural And Solution Speciation Studies On Selected [Cu(Nn)(Oo)] Complexes And An Investigation Of Their Biomimetic Activity, Ros Generation And Their Cytotoxicity In Normoxic, Hypoxic And Anoxic Environments In Mcf-7 Breast Cancer-Derived Cells, Hollie Jenkins

Articles

Reactive oxygen species(ROS) generation with subsequent DNA damage is one of the principle mechanisms of action assigned to copper-based anticancer complexes. The efficacy of this type of chemotherapeutic may be reduced in the low oxygen environment of tumours. In this study the cytotoxicity of three complexes, [Cu(dips)(phen)] (1), [Cu(ph)(phen)]·2H2O (2) and [Cu(ph)(bpy)]·H2O (3) (disp: 3,5-diisopropylsalicylate, phen: 1,10- phenanthroline, ph: phthalate, bpy: 2,2′-bipyridyl) were assessed for anticancer activity in the breast-cancer derived MCF-7 line under normoxic, hypoxic and anoxic conditions. In an immortalised keratinocyte HaCaT cell line, the cytotoxicity of complexes 2 and 3 was significantly reduced under both normoxic and …

The Iris Clinic: A Protocol For A Mixed-Methods Study Evaluating The Management Of Hyperemesis Gravidarum, Eileen O'Brien, Jean Doherty, Sarah Louise Killeen, Melanie Bennett, Lillian Murtagh, Sinead Curran, Suzanne Murphy, Helen Mchale, Lucille Sheehy

Articles

Hyperemesis Gravidarum (HG) is a severe form of nausea and vomiting in pregnancy that affects 0.3–3% of women and has profound nutritional, physical and psychological consequences. Research is lacking regarding the most effective management of the condition. In response to patient feedback, a multidisciplinary HG day-case service (IRIS Clinic) was launched in 2020 at The National Maternity Hospital, Ireland. The clinic provides routine, day-case care in a comfortable space with pre-booked appointments. The MDT involves midwives, dietitians, perinatal mental health, obstetrics and pharmacy, and the nature of the clinic enables peer-to-peer support. As this clinic is the first of its …

A Qualitative Analysis Of Women's Postnatal Experiences Of Breastfeeding Supports During The Perinatal Period In Ireland, Niamh Lawlor, Lucia Prihodova, Deborah Byrne, Megan Etherton, Felicienne Rahill, Catie Wilson, Elizabeth J. O'Sullivan

Articles

Ireland has among the lowest rates of breastfeeding worldwide. Despite policies to support breastfeeding, breastfeeding initiation and exclusivity remain low in Ireland. Greater knowledge about support received in the maternity unit may—in part—shed light on why this is so. Our aim was to analyse women's experiences of the breastfeeding supports available in the early postnatal period in Ireland. We conducted an analysis of an open-ended question on a cross-sectional survey about breastfeeding support conducted in the Republic of Ireland in 2022. Participants were asked to provide comments about the breastfeeding support they received in the maternity unit or during your …

Comprehensive Genomic Characterization Of Cronobacter Sakazakii Isolates From Infant Formula Processing Facilities Using Whole-Genome Sequencing, Zeinab E.Mousavi, Leonard Koolman, Guerrino Macori, Séamus Fanning, Francis Butler, University College Dublin

Articles

Cronobacter sakazakii is an opportunistic pathogen linked to outbreaks in powdered infant formula (PIF), primarily causing meningitis and necrotizing enterocolitis. Whole-genome sequencing (WGS) was used to characterize 18 C. sakazakii strains isolated from PIF (powdered infant formula) manufacturing plants (2011–2015). Sequence Type (ST) 1 was identified as the dominant sequence type, and all isolates carried virulence genes for chemotaxis, flagellar motion, and heat shock proteins. Multiple antibiotic resistance genes were detected, with all isolates exhibiting resistance to Cephalosporins and Tetracycline. A significant correlation existed between genotypic and phenotypic antibiotic resistance. The plasmid Col(pHAD28) was identified in the isolates recovered from …

Adolescent Overweight And Obesity In Ireland—Trends And Sociodemographic Associations Between 1990 And 2020, Aoibhín Moore Heslin, Aisling O'Donnell, Laura Kehoe, Janette Walton, Albert Flynn, John Kearney, Breige Mcnulty

Articles

Background: Overweight and obesity in adolescence is a growing issue and can have a range of both short- and long-term consequences on health. Objectives: To analyse trends in adolescent weight status in Ireland across a 30-year period and to examine the influence of sociodemographic factors on overweight/obesity in Irish adolescents over time. Methods: Body composition and body mass index weight status of Irish adolescents were compared using data from three nationally representative, cross-sectional Irish national food consumption surveys from 1990, 2006 and 2020. Adjusted analysis of associations between socio-demographic factors with the risk of adolescent overweight/obesity at each time point …

Exploring The Impact Of Noise And Degradations On Heart Sound Classification Models, Davoud Shariat Panah, Andrew Hines, Susan Mckeever

Articles

The development of data-driven heart sound classification models has been an active area of research in recent years. To develop such data-driven models in the first place, heart sound signals need to be captured using a signal acquisition device. However, it is almost impossible to capture noise-free heart sound signals due to the presence of internal and external noises in most situations. Such noises and degradations in heart sound signals can potentially reduce the accuracy of data-driven classification models. Although different techniques have been proposed in the literature to address the noise issue, how and to what extent different noise …

Persuasive Communication Systems: A Machine Learning Approach To Predict The Effect Of Linguistic Styles And Persuasion Techniques, Annye Braca, Pierpaolo Dondio

Articles

Prediction is a critical task in targeted online advertising, where predictions better than random guessing can translate to real economic return. This study aims to use machine learning (ML) methods to identify individuals who respond well to certain linguistic styles/persuasion techniques based on Aristotle’s means of persuasion, rhetorical devices, cognitive theories and Cialdini’s principles, given their psychometric profile.

Detection Of Grape Clusters In Images Using Convolutional Neural Network, Mohammad Osama Shahzad, Anas Bin Aqeel, Waqar Shahid Qureshi

Articles

Convolutional Neural Networks and Deep Learning have revolutionized every field since their inception. Agriculture has also been reaping the fruits of developments in mentioned fields. Technology is being revolutionized to increase yield, save water wastage, take care of diseased weeds, and also increase the profit of farmers. Grapes are among the highest profit-yielding and important fruit related to the juice industry. Pakistan being an agricultural country, can widely benefit by cultivating and improving grapes per hectare yield. The biggest challenge in harvesting grapes to date is to detect their cluster successfully; many approaches tend to answer this problem by harvest …

Nesnet: A Deep Network For Estimating Near-Surface Pollutant Concentrations, Prasanjit Dey, Bibhash Pran Das, Yee Hui Lee, Soumyabrata Dev

Articles

Atmospheric pollution has become a serious threat in recent years. The advancements and expansion of industrial activity and civilization have been the major catalysts. With serious consequences like climate change and global warming, the onset of which is already being observed, keeping a check on atmospheric pollutant levels is now more important than ever. Trace gases play a major role in atmospheric chemistry. Many of these are also regarded as major atmospheric pollutants. The concentration of gases, such as (SO2), (O3), (NO2), etc., are indicators of air quality. Therefore, in this study, we primarily concern ourselves with concentrations of NO2, …

A Multidimensionality Reduction Approach To Rainfall Prediction, Menatallah Abdel Azeem, Prasanjit Dey, Soumyabrata Dev

Articles

The rainfall has an impact on various fields and industries, including transportation, construction, tourism, health, and wildlife preservation. Accurate rainfall prediction is essential for mitigating the negative impact of rainfall on these sectors. However, previous studies on rainfall prediction have been mainly based on datasets from North America, Europe, Australia, and Central Asia, covering different periods. This study proposes using weather datasets covering the past 5 to 10 years to capture recent patterns in weather data. Additionally, the curse of dimensionality can impact model performance and lead to overfitting. Therefore, this study proposes utilizing dimensionality reduction techniques to ensure that …