Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2023

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 74161 - 74190 of 77355

Full-Text Articles in Entire DC Network

Length-Weight Relationships And Relative Condition Factors Of Three Coral-Associated Lutjanus Species From Terengganu Waters Of The South China Sea, Malaysia, Md. Moshiur Rahman, Nur Asma Ariffin, Ying Giat Seah, Tun Nurul Aimi Mat Jaafar, Ahasan Habib Jan 2023

Length-Weight Relationships And Relative Condition Factors Of Three Coral-Associated Lutjanus Species From Terengganu Waters Of The South China Sea, Malaysia, Md. Moshiur Rahman, Nur Asma Ariffin, Ying Giat Seah, Tun Nurul Aimi Mat Jaafar, Ahasan Habib

Turkish Journal of Zoology

The present study offers the first report of length-weight relationships (LWRs) and relative condition factor (K$_{n}$) of coralassociated snapper fishes namely: Lutjanus johnii, L. quinquelineatus, and L. xanthopinnis collected from Pulau Kambing fish landing port, Terengganu waters of South China Sea, Malaysia. This study also offers a new maximum total length of 26.8 cm (standard length of 21.3 cm) for L. xanthopinnis. A total of 861 specimens were collected monthly from March 2022 to February 2023 that were caught by using different types of fishing gear such as gill nets (mesh size 45-48 mm), hooks (numbers 9-12), and …

Go to article

The Impact Of Bracing On Kinesiophobia And Recovery In Acl Reconstruction Patients: A Case Study, N Valdecanas, K Neelon, K Braunreiter Jan 2023

The Impact Of Bracing On Kinesiophobia And Recovery In Acl Reconstruction Patients: A Case Study, N Valdecanas, K Neelon, K Braunreiter

Clinical Practice in Athletic Training

Introduction: With 100,000 to 200,000 cases reported in the U.S. yearly, the anterior cruciate ligament (ACL) is a commonly torn structure in the knee among contact and non-contact sports. As medical research on ACL injuries grows, ACL reconstruction (ACLR) continues to be the preferred surgical intervention. Due to extensive rehabilitation timeline requirements, ACLR patients may face physical and psychosocial circumstances affecting their overall recovery. At any point in rehabilitation the patient may experience kinesiophobia, or an irrational fear relating to further injury from participation in physical movement, especially with return to running, jumping, and sports-specific programs. Functional bracing has been …

Go to article

Twelfth Rib Avulsion Fracture In A Collegiate Baseball Pitcher: A Case Report., L K. Warner, A P. Jacobsen, R M. Galbraith, C Hodges, B J. Warner, S A. Cage Jan 2023

Twelfth Rib Avulsion Fracture In A Collegiate Baseball Pitcher: A Case Report., L K. Warner, A P. Jacobsen, R M. Galbraith, C Hodges, B J. Warner, S A. Cage

Clinical Practice in Athletic Training

Background: A 21-year-old male collegiate baseball player reported to the athletic training staff after experiencing acute pain in his left side following throwing a pitch. The patient experienced immediate difficulty with active lateral flexion and trunk rotation. Palpation revealed spasm and tenderness along the internal and external oblique muscle. The patient reported having subluxed a rib on a previous occasion. While the pain experienced was similar, the patient stated that there was more pain along the muscle bellies of the internal and external oblique muscles compared to the previous injury. No difficulties with breathing, bowel movements, or urination were reported. …

Go to article

The Diagnosis, Rehabilitation, And Treatment Of Posterior Impingement In A High School Baseball Pitcher, K Tisdale Jan 2023

The Diagnosis, Rehabilitation, And Treatment Of Posterior Impingement In A High School Baseball Pitcher, K Tisdale

Clinical Practice in Athletic Training

Introduction: Posterior impingement, also known as internal impingement, is a type of secondary impingement that is caused by overuse and repetitive movements of the shoulder overhead during motions such as throwing, spiking, etc. A combination of shoulder abduction and external rotation produces impingement of the infraspinatus and/or of the supraspinatus against the posterior-superior glenoid. Posterior impingement is common in overhead athletes, and this mechanism is usually seen during the cocking phase of throwing. Someone suffering from posterior impingement may complain of posterior shoulder pain, posterior stiffness and decline in performance. Patient Information: In this case study, a 15- year-old male …

Go to article

Acute Management Of An Abdominal Cavity Perforation In A Collegiate Baseball Pitcher: A Case Report., D M. Gallegos, A P. Jacobsen, R M. Galbraith, R L. Peebles, B J. Warner, S A. Cage Jan 2023

Acute Management Of An Abdominal Cavity Perforation In A Collegiate Baseball Pitcher: A Case Report., D M. Gallegos, A P. Jacobsen, R M. Galbraith, R L. Peebles, B J. Warner, S A. Cage

Clinical Practice in Athletic Training

Background: A 21-year-old male collegiate baseball player was performing warm up exercises when he tripped backwards onto one of the team’s pitching machines that had been laid on its side. Upon falling backward, the patient sustained a puncture wound through the left buttock from one of the machine’s handles. Unaware of the injury, the patient’s teammates lifted him off of the machine and retrieved the athletic trainer. Evaluation revealed a deep wound with visible adipose tissue and musculature. At this time, the patient was immediately transported to the emergency department of the local hospital, and team physicians were informed to …

Go to article

Hook Of The Hamate Fracture In A Collegiate Baseball Player Preceded By A Hamate Stress Fracture, H N. Parker, R M. Galbraith, A P. Jacobsen, C Hodges, B J. Warner, S A. Cage Jan 2023

Hook Of The Hamate Fracture In A Collegiate Baseball Player Preceded By A Hamate Stress Fracture, H N. Parker, R M. Galbraith, A P. Jacobsen, C Hodges, B J. Warner, S A. Cage

Clinical Practice in Athletic Training

Background: A 21-year-old male collegiate baseball player reported to the athletic training staff complaining of pain along the hypothenar eminence of the left hand. The patient’s pain was intensified when swinging a bat but remained constant even at rest. The patient reported symptoms beginning approximately three weeks prior to being evaluated by the athletic training staff, but delaying reporting symptoms in order to continue playing. Physical exam revealed tenderness over the hook of the hamate and hypothenar eminence, decreased active wrist extension, decreased grip strength, and pain with resisted pronation and supination. At this time, the patient was removed from …

Go to article

Slowing It Down: The Impact Of A Core Stabilization Program Of Hypermobile Sprinters, T Spears, J Gonzalez-Pons, J Debose Jan 2023

Slowing It Down: The Impact Of A Core Stabilization Program Of Hypermobile Sprinters, T Spears, J Gonzalez-Pons, J Debose

Clinical Practice in Athletic Training

Background: Low back pain (LBP) is a common complaint in sprinters, and it can present itself in many ways. One study published in 2019 surveyed 2539 runners; 22.6% of them reported LBP of some kind at least once within that year.5 LBP can occur in sprinters for many reasons. One study noted that muscle weakness, imbalance, and improper recruitment of hip and/or core musculature are a few sources of LBP in athletes.4 The aim of this study is to examine the effectiveness of a core stabilization program on athletes suffering from lumbar facet hypermobility. Differential Diagnosis: Conditions that are typically …

Go to article

Drug Interaction Potential Of Ankaferd Blood Stopper® In Human Hepatocarcinoma Cells, Asli Semi̇z Jan 2023

Drug Interaction Potential Of Ankaferd Blood Stopper® In Human Hepatocarcinoma Cells, Asli Semi̇z

Turkish Journal of Medical Sciences

Background/aim: Ankaferd blood stopper® (ABS) is an herbal extract consisting of mixtures of Alpinia officinarum, Gycyrrhiza glabra, Vitis vinifera, Thymus vulgaris, and Urtica dioica plants and has been used in recent years in Turkish medicine as a hemostatic agent. Despite its extensive usage, there is no information available about the drug interaction in HepG2 cells. The current work evaluated the effect of ABS on the expression of CYP1A1-1A2, CYP2E1, and CYP3A4 isozymes that are primarily involved in drug and carcinogen metabolism. Materials and methods: We selected HepG2 cells as in vitro cellular models of the human liver. The cells were …

Go to article

Low Ferritin Count In Female Collegiate Soccer Player Presents As Concussion, E N. Nelson, T D. Pitcock, M K. Knoblauch, L J. Harrison Jan 2023

Low Ferritin Count In Female Collegiate Soccer Player Presents As Concussion, E N. Nelson, T D. Pitcock, M K. Knoblauch, L J. Harrison

Clinical Practice in Athletic Training

Background: Women’s soccer leads the National Collegiate Athletic Association for having the highest number of concussions in female sports. Common symptoms of concussion can include light headedness, headaches, and dizziness, but these symptoms are not exclusive to concussions. Female athletes may experience nutritional deficits that can lead to a wide range of symptoms mimicking those commonly experienced with a concussion such as headaches, dizziness, and fatigue. The patient in this case is a 21- year-old female soccer athlete who presented with sensitivity to light, light headedness, nausea, and fatigue after experiencing repeated ‘headers’ as well as a collision during a …

Go to article

Cover And Contents Jan 2023

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Go to article

Improvement In Endothelial Function In Hypertensive Patients After Ramadan Fasting: Effects Of Cortisol, Erkan Demi̇rci̇, Eyüp Özkan Jan 2023

Improvement In Endothelial Function In Hypertensive Patients After Ramadan Fasting: Effects Of Cortisol, Erkan Demi̇rci̇, Eyüp Özkan

Turkish Journal of Medical Sciences

Background/aim: There are studies on the effects of Ramadan fasting (RF), which is one of the intermittent fasting diets, on both hypertension and endothelial function. However, the relationship between possible improvements in endothelial function and blood pressure after RF is not clear. In this study, we aimed to evaluate the effects of RF on blood pressure and endothelial dysfunction in patients with arterial hypertension (HT). Materials and methods: Sixty-four HT patients, aged 45-65, who were followed up in the Cardiology Department of Kayseri City Hospital and fasted during Ramadan between 13 April and 13 May 2021 with their self-consents were …

Go to article

A Prospective Study For An Alternative Probe Site For Pulse Oximetry Measurement In Male Patients With Severe Burn Trauma: Penile Shaft, Yeşi̇m Andiran Şenayli, Gülsen Keski̇n, Mi̇ne Akin, Ati̇lla Şenayli, Rabi̇a Ata, Gökhan Demi̇rtaş, Emrah Şenel Jan 2023

A Prospective Study For An Alternative Probe Site For Pulse Oximetry Measurement In Male Patients With Severe Burn Trauma: Penile Shaft, Yeşi̇m Andiran Şenayli, Gülsen Keski̇n, Mi̇ne Akin, Ati̇lla Şenayli, Rabi̇a Ata, Gökhan Demi̇rtaş, Emrah Şenel

Turkish Journal of Medical Sciences

Background/aim: Authors widely use pulse oximetry in clinical monitoring of heart rate (HR) and peripheral oxygen saturation (SpO2) by attachment to the fingers; however, there can be a need for an alternative attachment site, especially for burned patients. We investigate the availability of a pulse oximeter probe attached to the penile shaft as an alternative site in pediatric male patients if all extremities became unavailable for pulse oximetry measurement due to severe burn and/or trauma. Materials and methods: We designed a prospective comparative study in a training and research hospital. After local ethical committee approval, pediatric male cases eligible for …

Go to article

Resveratrol Attenuated High Intensity Exercise Training-Induced Inflammation And Ferroptosis Via Nrf2/Fth1/Gpx4 Pathway In Intestine Of Mice, Zhe Xu, Xiaonan Sun, Bin Ding, Ming Zi, Yan Ma Jan 2023

Resveratrol Attenuated High Intensity Exercise Training-Induced Inflammation And Ferroptosis Via Nrf2/Fth1/Gpx4 Pathway In Intestine Of Mice, Zhe Xu, Xiaonan Sun, Bin Ding, Ming Zi, Yan Ma

Turkish Journal of Medical Sciences

Background/aim: Moderate exercise has beneficial effects for human health and is helpful for the protection against several diseases. However, high intensity exercise training caused gastrointestinal syndrome. Resveratrol, a plant extract, plays a vital role in protecting various organs. However, whether resveratrol protected mice against high intensity exercise training-induced intestinal damage remains unclear. In this study, our objective was to investigate the protective effects and mechanism of resveratrol in high intensity exercise training-treated mice. Materials and methods: Mice were treated with swimming exercise protocol and/or resveratrol (15 mg/kg/day) for 28 consecutive days. Then, the mice were sacrificed, and a series of …

Go to article

Screening Of Antigliadin And Antitissue Transglutaminase Antibodies In Patients With Chronic Plaque Psoriasis: A Case-Control Study, Burhan Engi̇n, Chinara Huseynova, Tümay Ak, Ali̇ Yağiz Ayla, Günay Can, Serdal Uğurlu Jan 2023

Screening Of Antigliadin And Antitissue Transglutaminase Antibodies In Patients With Chronic Plaque Psoriasis: A Case-Control Study, Burhan Engi̇n, Chinara Huseynova, Tümay Ak, Ali̇ Yağiz Ayla, Günay Can, Serdal Uğurlu

Turkish Journal of Medical Sciences

Background/aim: In this study, we aimed to investigate different types of celiac antibodies in psoriasis patients and to see if the presence of the antibodies was associated with other variables. Materials and methods: We included patients with plaque psoriasis who were followed up in our dermatology clinic between February 2019 and February 2021 and added a healthy control group for comparison. The antibodies studied were serum antitissue transglutaminase (tTG)-IgA, tTG-IgG, antigliadin antibody (AGA)-IgA, and AGA-IgG. The patients' records were used to note age, sex, the pattern of psoriasis involvement, psoriasis area and severity index (PASI), presence of hypertension, presence of …

Go to article

Could Maternal Serum Mfg-E8 Level Predict Adverse First Trimester Pregnancy Outcome? A Preliminary Study, Bi̇rcan Elçi̇, Zeynep Yalçinkaya, Ercan Teki̇n, Şükrü Bakirci, Cemi̇le Dayangan Sayan, Üçler Kisa, Merti̇han Kurdoğlu, Zehra Sema Özkan, Nevi̇n Sağsöz Jan 2023

Could Maternal Serum Mfg-E8 Level Predict Adverse First Trimester Pregnancy Outcome? A Preliminary Study, Bi̇rcan Elçi̇, Zeynep Yalçinkaya, Ercan Teki̇n, Şükrü Bakirci, Cemi̇le Dayangan Sayan, Üçler Kisa, Merti̇han Kurdoğlu, Zehra Sema Özkan, Nevi̇n Sağsöz

Turkish Journal of Medical Sciences

Background/aim: Milk fat globule-epidermal growth factor 8 (MFG-E8) is expressed in the endometrial epithelium and its expression increases during the implantation process. Due to this knowledge, we aimed to investigate the maternal serum MFG-E8 levels on both healthy pregnant women in the first trimester and pregnant women complicated with missed abortion and threatened abortion in the first trimester. Materials and methods: This prospective, cross-sectional study was conducted in a tertiary referral hospital, department of obstetrics between July 2020 and February 2021 after ethical committee approval. The study population was consisted of 30 healthy pregnant women (HP) in the first trimester, …

Go to article

Effects Of Testosterone Treatment On Anal Sphincter Damage Repair In Ovariectomized Rats, İrem Şenyuva, Duygu Baki̇ Acar, Hasan Hüseyi̇n Demi̇rel, Ece Tunç Jan 2023

Effects Of Testosterone Treatment On Anal Sphincter Damage Repair In Ovariectomized Rats, İrem Şenyuva, Duygu Baki̇ Acar, Hasan Hüseyi̇n Demi̇rel, Ece Tunç

Turkish Journal of Medical Sciences

Background/aim: Fecal incontinence (FI) generally occurs with anal sphincter damage caused by vaginal delivery in women, obvious FI can develop in the postmenopausal stage. This pelvic floor dysfunction has no rational medical therapeutic options. We investigated the effect of testosterone treatment on the anal sphincter structure, serum thiol/disulfide levels, uterine tissue, and body composition in female rats in an experimental menopause-FI model. Materials and methods: The animal experiments were performed between September and November 2020 at Experimental Animal Application and Research Center, Afyon Kocatepe University, Afyonkarahisar, Turkey. Thirty-two female rats were divided into four groups: sham, saline, 10 mg/kg testosterone …

Go to article

The Diagnostic Value Of N-Terminal Probrain Natriuretic Peptides To Differentiate Neonatal Pneumoniae And Transient Tachypnea Of The Newborn, Zeynep Arslan, Serdar Alan, Di̇dem Ali̇efendi̇oğlu Jan 2023

The Diagnostic Value Of N-Terminal Probrain Natriuretic Peptides To Differentiate Neonatal Pneumoniae And Transient Tachypnea Of The Newborn, Zeynep Arslan, Serdar Alan, Di̇dem Ali̇efendi̇oğlu

Turkish Journal of Medical Sciences

Background/aim: The primary objective of the study was to determine the diagnostic value of serum N-terminal probrain natriuretic peptide (NT-proBNP) levels to differentiate neonatal pneumonia (NP) and transient tachypnea of the newborn (TTN). The secondary objective was to investigate the prognostic role of NT-proBNP levels in neonates with severe respiratory distress (RD). Materials and methods: A prospective, observational, single-blinded study involving 58 late preterm and term newborns who were diagnosed with TTN or NP was conducted between June 2020 and June 2021 at a level-3 neonatal intensive care unit in Kırıkkale University Faculty of Medicine. TTN and NP groups were …

Go to article

What Is The Yield Of Ebus-Tbna For Re-Evaluation Of Previously Treated Non-Small-Cell Lung Cancer?, Ayperi̇ Öztürk, Tuğba Çi̇çek, Aydin Yilmaz Jan 2023

What Is The Yield Of Ebus-Tbna For Re-Evaluation Of Previously Treated Non-Small-Cell Lung Cancer?, Ayperi̇ Öztürk, Tuğba Çi̇çek, Aydin Yilmaz

Turkish Journal of Medical Sciences

Background/aAim: Locoregional recurrence in lung cancer still remains an important problem. We aimed to indicate the effectiveness of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for reevaluation in previously treated nonsmall cell lung cancer (NSCLC). Materials and methods: NSCLC patients who underwent EBUS for rebiopsy of suspicious recurrent or progressive lesions between January 2010 and June 2017 were reviewed. Patients were categorized into two groups based on the previous treatment modalities: Group 1 (G1) consisted of patients who had been treated with chemoradiotherapy, and Group 2 (G2) consisted of patients who had undergone radical surgery. Results: Of 115 patients, 100 patients …

Go to article

Turkish Validity And Reliability Of The Level Of Sitting Scale In Children With Cerebral Palsy, Kami̇le Uzun Akkaya, Sabi̇ha Bezgi̇n, Debra Field, Bülent Elbasan Jan 2023

Turkish Validity And Reliability Of The Level Of Sitting Scale In Children With Cerebral Palsy, Kami̇le Uzun Akkaya, Sabi̇ha Bezgi̇n, Debra Field, Bülent Elbasan

Turkish Journal of Medical Sciences

Background/aim: The Level of Sitting Scale (LSS) is a valid and reliable classification index that categorizes sitting ability. The aim of this study is to establish the Turkish validity and reliability of the LSS in children with cerebral palsy (CP). Materials and methods: In total, 165 children (75 girls and 90 boys) between the ages of 4 and 18 years who were diagnosed with CP were included in the study. All children were evaluated by two independent physiotherapists for the interrater reliability analysis of the LSS and were reevaluated 1 week later by the same physiotherapist for the intrarater reliability …

Go to article

The Reliability And Validity Of The Turkish Version Of The Self-Administered Neck Mobility Assessment Tool (S-Rom-Neck) In Patients With Chronic Neck Pain, Fati̇h Özden, Emi̇ne Aslan Telci̇, Serbay Şekeröz, Nuray Akkaya Jan 2023

The Reliability And Validity Of The Turkish Version Of The Self-Administered Neck Mobility Assessment Tool (S-Rom-Neck) In Patients With Chronic Neck Pain, Fati̇h Özden, Emi̇ne Aslan Telci̇, Serbay Şekeröz, Nuray Akkaya

Turkish Journal of Medical Sciences

Background/aim: The self-administered neck mobility assessment tool (S-ROM-Neck) is the subjective cervical region range of motion (S-ROM) assessment scale. The study aimed to demonstrate the reliability and validity of the Turkish version of the S-ROM-Neck in patients with chronic neck pain. Materials and methods: A cross-sectional study was conducted with a total of 60 chronic neck pain patients in the Physical Therapy and Rehabilitation Clinic of Pamukkale University Hospital between January and August 2021. The mean age of the individuals was 34.1 ± 9.9 years. Patients were assessed with S-ROM-Neck twice to prove the test-retest reliability. In addition, Visual Analogue …

Go to article

The Effects Of Early Short-Term Insulin Treatment Vs. Glimepiride On Beta Cell Function In Newly Diagnosed Type 2 Diabetes With Hba1c Above 9%, Jelena Stojanovic, Marina Andjelic-Jelic, Miljanka Vuksanovic, Milica Marjanovic-Petkovic, Biljana Jojic, Marko Stojanovic, Teodora Beljic-Zivkovic Jan 2023

The Effects Of Early Short-Term Insulin Treatment Vs. Glimepiride On Beta Cell Function In Newly Diagnosed Type 2 Diabetes With Hba1c Above 9%, Jelena Stojanovic, Marina Andjelic-Jelic, Miljanka Vuksanovic, Milica Marjanovic-Petkovic, Biljana Jojic, Marko Stojanovic, Teodora Beljic-Zivkovic

Turkish Journal of Medical Sciences

Background/aim: Type 2 diabetes mellitus (T2D) is a complex metabolic impairment. Beta cell (BC) failure is the most challenging among its pathogenetic mechanisms. Recognizing reversible contributors to BC failure could guide individualized approach to early T2D treatment. The aim of this study was to compare early short-term insulin treatment vs. glimepiride, both added to metformin, on BC function, glycemic and lipid control, during 12-month follow-up. Patients and methods: Eighty newly diagnosed T2D patients, 30-65 years of age, presenting with HbA1c ≥ 9% were enrolled in the study. They were randomly assigned to single-month initial insulin therapy (INS) added to metformin, …

Go to article

Investigation Of The Value Of Hematological Biomarkers In The Clinical Differential Diagnosis Of Igg4-Rd, Hazan Karadeni̇z, Aslihan Avanoğlu Güler, Riza Can Kardaş, Muzaffer Karadeni̇z, Hati̇ce Paşaoğlu, Hami̇t Küçük, Berna Göker, Abdurrahman Tufan, Mehmet Aki̇f Öztürk Jan 2023

Investigation Of The Value Of Hematological Biomarkers In The Clinical Differential Diagnosis Of Igg4-Rd, Hazan Karadeni̇z, Aslihan Avanoğlu Güler, Riza Can Kardaş, Muzaffer Karadeni̇z, Hati̇ce Paşaoğlu, Hami̇t Küçük, Berna Göker, Abdurrahman Tufan, Mehmet Aki̇f Öztürk

Turkish Journal of Medical Sciences

Background/aim: IgG4- related disease (IgG4- RD) is a systemic fibroinflammatory disease whose pathogenesis has not been completely elucidated. Due to the novelty and complexity of the diagnostic criteria, it is difficult to distinguish from the diseases included in the differential diagnosis without tissue biopsy. This study aimed to discover new biomarkers that can help for disease diagnosis and its differential diagnosis by reviewing the relationships between neutrophil-lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI). Materials and methods: Thirty IgG4- RD, 38 granulomatous polyangiitis (GPA), and 46 sarcoidosis patients presenting to the …

Go to article

The Effect Of Different Boron Compounds On Nutrient Digestibility, Intestinal Nutrient Transporters, And Liver Lipid Metabolism, Emre Şahi̇n, Cemal Orhan, Füsun Erten, Fi̇kretti̇n Şahi̇n, Nurhan Şahi̇n, Kazi̇m Şahi̇n Jan 2023

The Effect Of Different Boron Compounds On Nutrient Digestibility, Intestinal Nutrient Transporters, And Liver Lipid Metabolism, Emre Şahi̇n, Cemal Orhan, Füsun Erten, Fi̇kretti̇n Şahi̇n, Nurhan Şahi̇n, Kazi̇m Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: Gastrointestinal health is essential for maintaining a healthy lifestyle. Improving nutrient absorption and energy metabolism are the critical targets for intestinal health. This study aimed to determine the effects of different boron (B) derivatives on nutrient digestibility, intestinal nutrient transporters, and lipid metabolism in rats. Materials and methods: Twenty-one rats were allocated to three groups (n = 7) as follows: (i) Control, (ii) Sodium pentaborate pentahydrate (SPP), and (iii) boric acid (BA). The rats were fed a chow diet (AIN-93M) and supplemented with 8 mg/kg elemental B from SPP (45.2 mg/kg BW) and BA (42.7 mg/kg BW) via oral …

Go to article

Effectiveness Of Ultrasonography-Guided Caudal Epidural Steroid Injection Compared To The Fluoroscopic Application, Emrullah Cem Kesi̇lmez, Kasim Zafer Yüksel, Ayşe Azak Bozan, Cengi̇zhan Yavuz Jan 2023

Effectiveness Of Ultrasonography-Guided Caudal Epidural Steroid Injection Compared To The Fluoroscopic Application, Emrullah Cem Kesi̇lmez, Kasim Zafer Yüksel, Ayşe Azak Bozan, Cengi̇zhan Yavuz

Turkish Journal of Medical Sciences

Background/aim: Caudal epidural steroid injection (CESI) has been increasingly used for treating lower back pain. However, there is still significant controversy about the efficacy and safety of different imaging techniques used to guide CESI. In this context, the objective of this study is to compare the efficacies of fluoroscopy- and ultrasonography-guided CESI in patients with chronic lower back pain. Materials and methods: The population of this retrospective, observational study consisted of all consecutive patients who underwent CESI for lower back pain between 2018 and 2020. Of the 371 patients included in the study sample, 192 had undergone fluoroscopy- guided CESI …

Go to article

A National, Multicenter, Retrospective Study Evaluating Retention Rate And Efficacy Of Tocilizumab Treatment In Patients With Active Rheumatoid Arthritis Who Had An Inadequate Response To Csdmards And/Or Tnf Inhibitors, Güzi̇de Nevsun İnanç, Mustafa Ender Terzi̇oğlu, Yusuf Karabulut, Zevcet Yilmaz, Emi̇ne Fi̇gen Tarhan, Mehmet Emi̇n Eneci̇k, Ali̇ Şahi̇n, Adem Küçük, Ayşe Ayan, Meti̇n Özgen, Uğur Karasu, Servet Yolbaş Jan 2023

A National, Multicenter, Retrospective Study Evaluating Retention Rate And Efficacy Of Tocilizumab Treatment In Patients With Active Rheumatoid Arthritis Who Had An Inadequate Response To Csdmards And/Or Tnf Inhibitors, Güzi̇de Nevsun İnanç, Mustafa Ender Terzi̇oğlu, Yusuf Karabulut, Zevcet Yilmaz, Emi̇ne Fi̇gen Tarhan, Mehmet Emi̇n Eneci̇k, Ali̇ Şahi̇n, Adem Küçük, Ayşe Ayan, Meti̇n Özgen, Uğur Karasu, Servet Yolbaş

Turkish Journal of Medical Sciences

Background/aim: To describe the disease activity and retention rate in rheumatoid arthritis (RA) patients with inadequate response (IR) to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) and/or tumor necrosis factor inhibitors (TNFis) who were prescribed tocilizumab (TCZ) as first-line or second-line biologic treatment in real-world setting. Materials and methods: Data gathered from patients' files was used in a multicenter and retrospective context. Retention rates and the Disease Activity Score in 28 joints with CRP (DAS28-CRP) were evaluated at time points. The relationship of drug efficacy with factors such as smoking, obesity, and previous use of TNFis was also examined. Results: One …

Go to article

Exosome-Mediated Long Noncoding Rna (Lncrna) Part1 Suppresses Malignant Progression Of Oral Squamous Cell Carcinoma Via Mir-17-5p/Socs6 Axis, Yuheng Du, Yanjie Shuai, Hongling Wang, Huisheng Li, Yajing Li Jan 2023

Exosome-Mediated Long Noncoding Rna (Lncrna) Part1 Suppresses Malignant Progression Of Oral Squamous Cell Carcinoma Via Mir-17-5p/Socs6 Axis, Yuheng Du, Yanjie Shuai, Hongling Wang, Huisheng Li, Yajing Li

Turkish Journal of Medical Sciences

Background/aim: Exosomes derived from oral squamous cell carcinoma (OSCC) could modulate OSCC development. This study aimed to explore effects of exosome-mediated lncRNA PART1 on OSCC cells. Materials and methods: This study was performed in Tianjin Medical University Cancer Institute from February 2021 to March 2022. Bioinformatic analysis was performed on the public database GEPIA (http://gepia.cancer-pku.cn/). Exosomes isolated from cell lines squamous cell carcinoma 9 (SCC9) and Centre Antoine Lacassagne-27 (CAL27) were identified by transmission electron microscope and western blot. Exosome-mediated lncRNA PART1, microRNA-17-5p(miR-17-5p) and suppressor of cytokine signaling 6(SOCS6) RNA expressions were assessed by quantitative reverse transcription polymerase chain reaction …

Go to article

Evaluation Of Treatment Regimens And Long-Term Clinical Outcomes In Patients With Isoniazid-Resistant Pulmonary Tuberculosis: A 5-Year Follow-Up, Ayşe Feyza Aslan, Medi̇ha Gönenç Ortaköylü, Belma Akbaba Bağci, Sezer Toprak Jan 2023

Evaluation Of Treatment Regimens And Long-Term Clinical Outcomes In Patients With Isoniazid-Resistant Pulmonary Tuberculosis: A 5-Year Follow-Up, Ayşe Feyza Aslan, Medi̇ha Gönenç Ortaköylü, Belma Akbaba Bağci, Sezer Toprak

Turkish Journal of Medical Sciences

Background/aim: Considering its early bactericidal activity, isoniazid (H) is an important first-line agent in tuberculosis (TB) treatment. The aim of this study was to evaluate the treatment regimens and results of H-resistant pulmonary TB patients. Materials and methods: We retrospectively evaluated treatment regimens and results of 188 H-resistant pulmonary TB patients who were treated in our center between January 2015 and December 2017. Treatment regimens applied were noted and treatment outcomes were recorded. The long-term results were evaluated. Results: Totally 174 (92.6%) of 188 patients with H-resistant pulmonary TB achieved treatment success. Ninety-seven patients (51.6%) were cured and 77 patients …

Go to article

T1 Relaxation Time Is Prolonged In Healthy Aging: A Whole Brain Study, Hayri̇ye Aktaş Di̇nçer, Ahmet Muhteşem Ağildere, Di̇dem Gökçay Jan 2023

T1 Relaxation Time Is Prolonged In Healthy Aging: A Whole Brain Study, Hayri̇ye Aktaş Di̇nçer, Ahmet Muhteşem Ağildere, Di̇dem Gökçay

Turkish Journal of Medical Sciences

Background/aim: Measurement of tissue characteristics such as the longitudinal relaxation time (T1) provides complementary information to the volumetric and surface based structural analyses. We aimed to investigate T1 relaxation time characteristics in healthy aging via an exploratory design in the whole brain. The data processing pipeline was designed to minimize errors related to aging effects such as atrophy. Materials and methods: Sixty healthy participants underwent MRI scanning (28 F, 32 M, age range: 18-78, 30 young and 30 old) in November 2017-March 2018 at the Bilkent University UMRAM Center. Four images with varying flip angles with FLASH (fast low angle …

Go to article

The Role Of Endobronchial Ultrasonography Elastography In The Diagnosis Of Hilar And Mediastinal Lymph Nodes, Bariş Demi̇rkol, Eli̇f Tanriverdi̇, Şule Gül, Aysu Si̇nem Koç, Eli̇fe Akgün, Aytül Hande Yardimci, Kürşad Nuri̇ Baydi̇li̇, Erdoğan Çeti̇nkaya Jan 2023

The Role Of Endobronchial Ultrasonography Elastography In The Diagnosis Of Hilar And Mediastinal Lymph Nodes, Bariş Demi̇rkol, Eli̇f Tanriverdi̇, Şule Gül, Aysu Si̇nem Koç, Eli̇fe Akgün, Aytül Hande Yardimci, Kürşad Nuri̇ Baydi̇li̇, Erdoğan Çeti̇nkaya

Turkish Journal of Medical Sciences

Background/aim: Endobronchial ultrasonography (EBUS) is a minimally invasive diagnostic tool in the diagnosis of mediastinal lymph nodes (LNs) and has sonographic features. We aimed to investigate the diagnostic accuracy of EBUS elastography, which evaluates tissue compressibility integrated into EBUS, on malignant vs. benign mediastinal-hilar LNs. Materials and methods: A single-center, prospective study was conducted at the University of Health Sciences Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital between 01/10/2019 and 15/11/2019. The features of 219 LNs evaluated by thoracic computed tomography (CT), positron emission tomography (PET)/CT, EBUS sonography and EBUS elastography were recorded. The LNs sampled by …

Go to article

Clinical Characteristics And Outcomes Of Continuous Renal Replacement Therapy Performed On Younger Children Weighing Up To 10 Kg, Emrah Gün, Anar Gurbanov, Özlem Saritaş Naki̇p, Ahmet Yöntem, Ayşen Durak Aslan, Edi̇n Botan, Fevzi̇ Kahveci̇, Serhan Özcan, Ebru Azapağasi, Serhat Emeksi̇z, Mutlu Uysal Yazici, Selman Kesi̇ci̇, Özden Özgür Horoz, Ömer Erdeve, Benan Bayrakci̇ Jan 2023

Clinical Characteristics And Outcomes Of Continuous Renal Replacement Therapy Performed On Younger Children Weighing Up To 10 Kg, Emrah Gün, Anar Gurbanov, Özlem Saritaş Naki̇p, Ahmet Yöntem, Ayşen Durak Aslan, Edi̇n Botan, Fevzi̇ Kahveci̇, Serhan Özcan, Ebru Azapağasi, Serhat Emeksi̇z, Mutlu Uysal Yazici, Selman Kesi̇ci̇, Özden Özgür Horoz, Ömer Erdeve, Benan Bayrakci̇

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the clinical features, modality, complications, and effecting factors on the survival of children weighing up to 10 kg who received continuous renal replacement therapy (CRRT). Materials and methods: This study was a retrospective observational study conducted in five pediatric intensive care units in tertiary hospitals in Turkey between January 2015 and December 2019. Results: One hundred and forty-one children who underwent CRRT were enrolled in the study. The median age was 6 (range, 2-12) months, and 74 (52.5%) were male. The median weight of the patients was 6 (range, 4-8.35) kg and 52 (36.9%) …

Go to article

First Prev Next Last