Digital Commons Network^™

Keynote: Notions Of Writing Center Community And Some Challenges To Them, Carol Severino

The Writing Center Journal

It is crucial for writing center professionals who discuss community to ask ourselves what we mean by the term as applied to writing centers. In this keynote, I explore various notions of community that are influenced by writing center growth, expansion, and complexity, especially in relation to Iowa’s writing center. After relating a personal story about our new tutors’ traditional notion of community and an account of our own center’s expansion and growing complexity over the decades, which challenges their traditional notion, I discuss other obstacles to community, bringing in the critiques of writing center scholars. Finally, I synthesize what …

Solving The Problem Of The Reading Achievement Gap Among Spanish-Speaking English Language Learners In A West Texas Elementary School: An Applied Study, Narichica V. Handy

Doctoral Dissertations and Projects

The purpose of this study was to solve the problem of low reading achievement among English language learners at Wiley Elementary School in West Texas. A multi-method design was used, consisting of both qualitative and quantitative approaches. The first approach involved semistructured interviews with campus administrators, campus teaching coaches, and dual language teachers. The second approach involved conducting a focus group with campus administrators, campus teaching coaches, and dual language teachers. The third approach consisted of a document review of the State of Texas Assessments of Academic Readiness reading results. The findings resulted in several recommendations for solving the problem …

Rapid, High Throughput, Automated Detection Of Sars-Cov-2 Neutralizing Antibodies Against Wuhan-Wt, Delta And Omicron Ba1, Ba2 Spike Trimers, Narayanaiah Cheedarla, Hans P Verkerke, Sindhu Potlapalli, Kaleb Benjamin Mclendon, Anamika Patel, Filipp Frank, William Henry O'Sick, Suneethamma Cheedarla, Tyler Jon Baugh, Gregory L Damhorst, Huixia Wu, Daniel Graciaa, Fuad Hudaib, David N Alter, Janetta Bryksin, Eric A Ortlund, Jeanette Guarner, Sara Auld, Sarita Shah, Wilbur Lam, Dawn Mattoon, Joseph M Johnson, David H Wilson, Madhav V Dhodapkar, Sean R Stowell, Andrew S Neish, John D Roback

Faculty, Staff and Student Publications

Traditional cellular and live-virus methods for detection of SARS-CoV-2 neutralizing antibodies (nAbs) are labor- and time-intensive, and thus not suited for routine use in the clinical lab to predict vaccine efficacy and natural immune protection. Here, we report the development and validation of a rapid, high throughput method for measuring SARS-CoV-2 nAbs against native-like trimeric spike proteins. This assay uses a blockade of human angiotensin converting enzyme 2 (hACE-2) binding (BoAb) approach in an automated digital immunoassay on the Quanterix HD-X platform. BoAb assays using Wuhan-WT (vaccine strain), delta (B.1.167.2), omicron BA1 and BA2 variant viral strains showed strong correlation …

Allogeneic Hematopoietic Cell Transplantation For Blastic Plasmacytoid Dendritic Cell Neoplasm: A Cibmtr Analysis, Hemant S. Murthy, Mei-Jie Zhang, Karen Chen, Sairah Ahmed, Uday Deotare, Siddhartha Ganguly, Ankit Kansagra, Fotios V. Michelis, Taiga Nishihori, Mrinal Patnaik, Muhammad Bilal Abid, Mahmoud Aljurf, Yasuyuki Arai, Ulrike Bacher, Talha Badar, Sherif M. Badawy, Karen Ballen, Minoo Battiwalla, Amer Beitinjaneh, Nelli Bejanyan, Vijaya Raj Bhatt, Valerie I. Brown, Rodrigo Martino, Jean-Yves Cahn, Paul Castillo, Jan Cerny, Saurabh Chhabra, Edward Copelan, Andrew Daly, Bhagirathbhai Dholaria, Miguel Angel Diaz Perez, César O. Freytes, Michael R. Grunwald, Shahrukh Hashmi, Gerhard C. Hildebrandt, Omer Jamy, Jacinth Joseph, Christopher G. Kanakry, Nandita Khera, Maxwell M. Krem, Yachiyo Kuwatsuka, Hillard M. Lazarus, Lazaros J. Lekakis, Hongtao Liu, Dipenkumar Modi, Pashna N. Munshi, Alberto Mussetti, Neil D. Palmisiano, Sagar S. Patel, David A. Rizzieri, Sachiko Seo, Mithun Vinod Shah, Akshay Sharma, Melhm Sohl, Scott R. Solomon, Matthew Ulrickson, Celalettin Ustun, Marjolein Van Der Poel, Leo F. Verdonck, John L. Wagner, Trent Wang, Baldeep Wirk, Amer Zeidan, Mark Litzow, Partow Kebriaei, Christopher S. Hourigan, Daniel J. Weisdorf, Wael Saber, Mohamed A. Kharfan-Dabaja

Department of Medical Oncology Faculty Papers

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy with a poor prognosis and considered incurable with conventional chemotherapy. Small observational studies reported allogeneic hematopoietic cell transplantation (allo-HCT) offers durable remissions in patients with BPDCN. We report an analysis of patients with BPDCN who received an allo-HCT, using data reported to the Center for International Blood and Marrow Transplant Research (CIBMTR). We identified 164 patients with BPDCN from 78 centers who underwent allo-HCT between 2007 and 2018. The 5-year overall survival (OS), disease-free survival (DFS), relapse, and nonrelapse mortality (NRM) rates were 51.2% (95% confidence interval [CI], 42.5-59.8), …

Communication And Community: The Impact Of Closed Facebook Groups On Athletic Trainers, Allison M. Schwartz-Strickland

Doctoral Dissertations and Projects

This qualitative research study will use semi-structured interviews to explore the motivations of athletic trainers using social media for professional collaboration. The socio-psychological tradition is used to frame the study. Communities of practice, uses and gratification theory, and the Wisdom of the Crowd model are used as the guiding theoretical perspectives as they provide a framework for understanding how and why athletic trainers use social media. This qualitative study sought to show the impact of closed Facebook Group participation on athletic trainers. How athletic trainers understand patient privacy laws when participating in closed Facebook groups for athletic trainers will also …

Current Management Issues In Health Information Technology, Gladys Dadson

Doctoral Dissertations and Projects

Health information technology can improve quality care delivery, thereby boosting the healthcare business reputation. However, it can negatively affect quality care delivery and lead to a negative business reputation if not efficiently managed. This single qualitative study aimed to explore the causes of the inefficiencies in managing health information technology and strategies that healthcare organizations use to ensure its efficiencies. In a purposive sample, the researcher conducted telephone interviews with twenty-one participants from Lancaster General Hospital. The participants comprised medical doctors, Doctor of Nursing practitioners, managers of health informatics, and informatics specialists working in various divisions and E-health operations. Other …

The Perspectives Of Ghanaian Political Leaders And Citizens Concerning The Development And Implementation Of The Ghana Vision 2020 Development Plan, Kwame Aduhene-Kwarteng

Doctoral Dissertations and Projects

The purpose of this qualitative research case study is to collect, investigate, and assess Ghanaian citizens’ and political leaders’ perspectives and viewpoints regarding the success or failure of Ghana Vision 2020 and the challenges facing developing nations. The study used a descriptive approach to examine Ghana’s Vision 2020 and the country’s development challenges using a descriptive methodology and primary and secondary sources. The 105 participants for the study included 65 males and 40 females living in Ghana. The theoretical framework of this study are modernization, globalization, and dependency theories. To that end, the study set out to investigate the question: …

A Qualitative Study Of Music Therapy's Effectiveness On Treating Ptsd, Shariee Jones

Doctoral Dissertations and Projects

The purpose of this descriptive phenomenological study in this qualitative research described how music therapy has been beneficial to the treatment of trauma survivors suffering from post-traumatic stress disorder. The research in this study consisted of six participants and previous research to show how music therapy has been effective in treating PTSD. The six participants were individually interviewed based on their prior experiences with music therapy from Board Certified Music Therapists. For years, the U.S. Department of Veteran Affairs have used music therapy to treat trauma survivors with complementary and alternative medical treatment. Several studies have been done on music …

Motivation In Student Retention: A Phenomenology Of Non-Traditional Undergraduate Students In Online Learning, Jasmine Monique Reynolds

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenology study was to understand the experiences of non-traditional undergraduate students taking online courses at a public or a private university in Virginia. The self-determination theory, which guided this study, explained the motivated behaviors of intrinsic and extrinsic needs that affect the determination in non-traditional students completing a task. Self-determination theory provided the theoretical framework to answer the central research question for this study as well as the sub-questions: (1) What are the lived experiences of non-traditional students while taking online courses at a public or private university in Virginia? (2) What influences non-traditional students …

The Therapeutic Church, Isidro Morell

Doctoral Dissertations and Projects

This project aims to develop Nexus Point Church as a therapeutic environment. The Therapeutic Church environment is a supportive community, one member to another, ministering to each other empathetically, not service dependent or a dispenser of services. It is “Pew Neighbor” supportive and crisis intervention ready. The Therapeutic Church provides a therapeutic environment that heals interactively in spirit, mind, body, and relationship to improve the quality of life for the church member and those seeking help. This project identifies members as “Pew Neighbors” due to the proximity and continual closeness shared with those within the church community. Pew neighbors serve …

Resilience Through Relocation In Older Adulthood: An Interpretative Phenomenological Analysis, Holly Walker

Doctoral Dissertations and Projects

Resilience, the process and outcome of successful adaptation to a stressor, is important to maintain wellbeing through stressors such as relocation. Relocation is a common experience in late adulthood which can cause significant stress. The purpose of this study was to explore the lived experience of resilience and its relationship to strengths and resources following relocation in older adulthood. The research questions regarded participants’ description of experiencing resilience after relocation and strengths and resources that contributed to that experience. Data collection consisted of semi-structured interviews with a criterion sample of six adults aged 65 and older who had relocated within …

Sex And Violence: An Exploratory Study Of Changes In Male And Female Violent Offenders' Choices Of Weapon And Victim Over Time, Lindsey Hutton Nagle

Doctoral Dissertations and Projects

Violent offenses are part of the history of humankind, and as such, both male and female violent offenders have perpetrated these acts, often with gender differences between male and female offenders present. As more women leave the home and enter the workplace, the gap in gender roles has narrowed, so it follows that this narrowing may also be reflected in the actions of violent offenders. Although there are various explanations for the narrowing of the gender gap in crime, understanding the differences between male and female offenders can help inform gender-based interventions. To address this idea, the type of weapon …

Effectiveness Of Post-Abortion Bible Studies On Self-Forgiveness And Depression, Karen Haaland Hubbard

Doctoral Dissertations and Projects

Pro-choice and pro-life perspectives differ regarding adverse emotional symptoms after abortion. Pro-choice researchers maintain that abortion presents no more risk of emotional distress than carrying an unplanned pregnancy to term. However, pro-life researchers discuss evidence that abortion does increase the risk of adverse emotional symptoms that persist long after the abortion. Since many women seek faith-based interventions, the purpose of the current study was to examine the effectiveness of the post-abortion Bible study, Forgiven and Set Free by Linda Cochrane, in decreasing depression and increasing self-forgiveness. The first research question was, “Does participation in a post-abortion Bible study increase post-abortive …

Promises Made, Promises Kept? A Phenomenological Study Exploring The Experiences Of California Community College Promise Program Students And Their Pursuit Of A Bachelor's Degree, Eric R. Garcia

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the experiences of students formally enrolled in a California community college promise program at Mountain View Community College, Lakeview Community College, Hillcrest Community College, and Ocean Valley Community College, each located in Southern California. The theoretical framework guiding this study was grounded in Astin’s theory of student involvement which provided a lens to analyze the experiences of promise students and their pursuit of bachelor’s degrees. The central research question under investigation was: What do promise program students previously enrolled at a California community college that have transferred to a four-year …

A Phenomenological Study Exploring The Meaning Of First-Generation Students And Adjunct Faculty Relationships In Higher Education, Melissa Greenlee-Rasnake

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to explore how the first-generation student describes the meaning of developing a relationship with adjunct instructors at a community college and how this relationship influences their academic development and institutional sense of belonging. For the purpose of this study, the first-generation student and adjunct faculty relationship was defined as the formal and informal contact between the student and the faculty member. The theory guiding this study was that of proximal process and campus ecology developed by Urie Bronfenbrenner (1979) as it explores the importance of how the student’s environment and relationships influence their …

The Relationship Of Grit And Social Media Addiction For College Students, Tobias K. England

Doctoral Dissertations and Projects

This quantitative study explored the relationship between grit and social media. Researchers have noted a significant increase in the use of social media among college students that often results in negative outcomes, both personally and academically. Previous studies have shown that grit is a trait that negatively relates to various types of addictive behavior. However, little is known about the correlation between grit and social media addiction specifically. The purpose of this study was to determine the relationship between grit and social media addiction. This study collected data from the student populations of three private colleges and followed a correlational …

Multi-Site Identification And Generalization Of Clusters Of Walking Behaviors In Individuals With Chronic Stroke And Neurotypical Controls, Natalia Sánchez, Nicolas Schweighofer, Sara J. Mulroy, Ryan T. Roemmich, Trisha M. Keshar, Gelsy Torres-Oviedo, Beth E. Fisher, James M. Finley, Carolee J. Winstein

Physical Therapy Faculty Articles and Research

Background

Objectives

Methods

Perspective On The Utilization And The Outcome Of Digital Tools To Manage Chronic Diseases, Narjodh Singh

Applied Research Projects

The increasing aging population and the prevalence of chronic diseases among lower socioeconomic groups have led to higher healthcare spending on chronic care management. In this paper, the study revolves around the utilization of Information and Communication Technology (ICT) for the management of chronic diseases, with a particular focus on the elderly population. The study examines various digital health interventions, including eHealth, mHealth, electronic health records, remote monitoring, wearable devices, clinical decision support systems, telehealth, and telemedicine, in the context of chronic disease management. The opportunities, strengths, and weaknesses of digital technology are discussed, highlighting the potential benefits of ICT …

Evaluating The Contamination By Indoor Dust In Dubai, Yousef Nazzal, Alina Bărbulescu, Manish Sharma, Fares Howari, Muhammad Naseem

All Works

Nowadays, people spend most of their time indoors. Despite constantly cleaning these spaces, dust apparition cannot be avoided. Since dust can contain chemical elements that negatively impact people's health, we propose the analysis of the metals from the indoor dust component collected in different locations in Dubai, UAE. Multivariate statistics (correlation matrix, clustering) and quality indicators (QI)-Igeo, PI, EF, PLI, Nemerow-were used to assess the contamination level with different metals in the dust. We proposed two new QIs (CPI and AQI) and compared the results with those provided by the most used indices-PLI and Nemerow. It is shown that high …

121st Sibley Lecture: American Democracy In Peril, J. Michael Luttig

Georgia Law Review

No abstract provided.

Confusing Cy Près, Christopher J. Ryan Jr.

Georgia Law Review

American courts have increasingly considered the possibility of prolonging the life of charitable trusts through cy près and the closely related doctrine of equitable deviation. This requires courts to interpret the material purposes of trusts and even the administrative terms on which settlors of charitable trusts condition gifts in trust made for public benefit. Yet, the implicit reasons why courts might invoke cy près to change a charitable trust’s material purpose have not been explored in significant depth heretofore—and neither has a common but vexing trend of courts conflating cy près with deviation, which negatively impacts charitable trust-making.

I analyze …

The Applications Docket, Greg Goelzhauser

Georgia Law Review

The Supreme Court’s applications docket, often misleadingly called the “shadow docket” or “emergency docket,” is controversial, complex, and poorly understood. Using original data spanning nearly two decades, I unravel the docket’s empirical foundations. Applications practice changed fundamentally in recent years. Contrary to conventional wisdom, dispositions declined on average, but this conceals divergent trends: among applications involving stays and injunctions, capital dispositions decreased while noncapital dispositions increased. Moreover, noncapital applications now comprise a larger share of the docket than capital applications. This shift enhances docket salience because, as I show, most capital applications are denied simultaneous to denying plenary review, while …

Title Ix At Fifty: Reimagining Institutional Liability Under Karasek's Pre-Assault Theory, Delaney R. Davis

Georgia Law Review

Unfortunately, sexual misconduct remains a pervasive problem on college campuses throughout the country. While victims of sexual harassment and assault can report these incidents to their university, these institutions often fail to respond adequately. Investigations into the alleged misconduct are often unnecessarily delayed and school officials neglect to inform victims about the status of their cases. Even more troubling, institutions opt to impose informal sanctions on perpetrators without consulting victims. In such instances, students can hold educational institutions accountable for these deficiencies by suing under Title IX. This is easier said than done. Typically, a plaintiff must prove that their …

20231117_Hslic Scholarship Day, Amy Weig-Pickering

HSLIC Blog Post

No abstract provided.

The Transcription Factor Irf4 Determines The Anti-Tumor Immunity Of Cd8+ T Cells, Hui Yan, Yulin Dai, Xiaolong Zhang, Hedong Zhang, Xiang Xiao, Jinfei Fu, Dawei Zou, Anze Yu, Tao Jiang, Xian C Li, Zhongming Zhao, Wenhao Chen

Faculty, Staff and Student Publications

Understanding the factors that regulate T cell infiltration and functional states in solid tumors is crucial for advancing cancer immunotherapies. Here, we discovered that the expression of interferon regulatory factor 4 (IRF4) was a critical T cell intrinsic requirement for effective anti-tumor immunity. Mice with T-cell-specific ablation of IRF4 showed significantly reduced T cell tumor infiltration and function, resulting in accelerated growth of subcutaneous syngeneic tumors and allowing the growth of allogeneic tumors. Additionally, engineered overexpression of IRF4 in anti-tumor CD8+ T cells that were adoptively transferred significantly promoted their tumor infiltration and transition from a naive/memory-like cell state into …

Interplay Of Gut Microbiota And Host Epithelial Mitochondrial Dysfunction Is Necessary For The Development Of Spontaneous Intestinal Inflammation In Mice, Kibrom M Alula, Alexander S Dowdell, Brittany Lebere, J Scott Lee, Cassandra L Levens, Kristine A Kuhn, Benny A Kaipparettu, Winston E Thompson, Richard S Blumberg, Sean P Colgan, Arianne L Theiss

Faculty, Staff and Students Publications

Background: Intestinal epithelial cell (IEC) mitochondrial dysfunction involvement in inflammatory bowel diseases (IBD), including Crohn's disease affecting the small intestine, is emerging in recent studies. As the interface between the self and the gut microbiota, IECs serve as hubs of bidirectional cross-talk between host and luminal microbiota. However, the role of mitochondrial-microbiota interaction in the ileum is largely unexplored. Prohibitin 1 (PHB1), a chaperone protein of the inner mitochondrial membrane required for optimal electron transport chain function, is decreased during IBD. We previously demonstrated that mice deficient in PHB1 specifically in IECs (Phb1i∆IEC) exhibited mitochondrial impairment, Paneth cell defects, gut …

The Eye Has It!, Adriana Sarmiento Clemente, Katherine J Williams, Richard C Allen, Morven S Edwards

Faculty, Staff and Students Publications

No abstract provided.

Efficient Thorax Disease Classification And Localization Using Dcnn And Chest X-Ray Images, Zeeshan Ahmad, Ahmad Kamran Malik, Nafees Qamar, Saif Ul Islam

Psychology Department Faculty Journal Articles

Thorax disease is a life-threatening disease caused by bacterial infections that occur in the lungs. It could be deadly if not treated at the right time, so early diagnosis of thoracic diseases is vital. The suggested study can assist radiologists in more swiftly diagnosing thorax disorders and in the rapid airport screening of patients with a thorax disease, such as pneumonia. This paper focuses on automatically detecting and localizing thorax disease using chest X-ray images. It provides accurate detection and localization using DenseNet-121 which is foundation of our proposed framework, called Z-Net. The proposed framework utilizes the weighted cross-entropy loss …

2023 November 27 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

Mycoplasma Genitalium In The Us (Mygenius): Surveillance Data From Sexual Health Clinics In 4 Us Regions, Lisa E Manhart, Gina Leipertz, Olusegun O Soge, Stephen J Jordan, Candice Mcneil, Preeti Pathela, Hilary Reno, Karen Wendel, Anika Parker, William M Geisler, Damon Getman, Matthew R Golden, Mygenius Study Team

2020-Current year OA Pubs

BACKGROUND: Mycoplasma genitalium (MG) is on the CDC Watch List of Antimicrobial Resistance Threats, yet there is no systematic surveillance to monitor change.

METHODS: We initiated surveillance in sexual health clinics in 6 cities, selecting a quota sample of urogenital specimens tested for gonorrhea and/or chlamydia. We abstracted patient data from medical records and detected MG and macrolide-resistance mutations (MRMs) by nucleic acid amplification testing. We used Poisson regression to estimate adjusted prevalence ratios (aPRs) and 95% CIs, adjusting for sampling criteria (site, birth sex, symptom status).

RESULTS: From October-December 2020 we tested 1743 urogenital specimens: 57.0% from males, 46.1% …